Κυριακή 15 Δεκεμβρίου 2019

Blood screening for heavy metals and organic pollutants in cancer patients exposed to toxic waste

Blood screening for heavy metals and organic pollutants in cancer patients exposed to toxic waste in southern Italy: A pilot study:

Journal of Cellular Physiology Blood screening for heavy metals and organic pollutants in cancer patients exposed to toxic waste in southern Italy: A pilot study
In Italy, in the eastern area of the Campania region, hazardous waste exposure has been suggested to associate with increased cancer development. We evaluated blood levels of heavy metals in 95 cancer patients residing in this area and in 27 healthy individuals. Our results showed high blood concentrations of heavy metals in some municipalities, including Giugliano, where Cd and Hg levels resulted significantly higher in cancer patients than in healthy controls.




Abstract

In Italy, in the eastern area of the Campania region, the illegal dumping and burning of waste have been documented, which could potentially affect the local population's health. In particular, toxic waste exposure has been suggested to associate with increased cancer development/mortality in these areas, although a causal link has not yet been established. In this pilot study, we evaluated blood levels of toxic heavy metals and persistent organic pollutants (POPs) in 95 patients with different cancer types residing in this area and in 27 healthy individuals. While we did not find any significant correlation between the blood levels of POPs and the provenance of the patients, we did observe high blood concentrations of heavy metals in some municipalities, including Giugliano, where many illegal waste disposal sites have previously been documented. Our results showed that patients with different cancer types from Giugliano had higher blood levels of heavy metals than healthy controls. Despite the obvious limitations of this exploratory study, our preliminary observations encourage further research assessing the possible association between exposure to hazardous waste, increased blood metals, and increased risk of cancer.

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