Pathogens, Vol. 8, Pages 281: A Recombinant Influenza A/H1N1 Carrying A Short Immunogenic Peptide of MERS-CoV as Bivalent Vaccine in BALB/c Mice Pathogens doi: 10.3390/pathogens8040281 Authors: Shehata Kandeil Mostafa Mahmoud Gomaa El-Shesheny Webby Kayali Ali Middle East Respiratory Syndrome Coronavirus (MERS-CoV) became a global human health threat since its first documentation in humans in 2012. An efficient vaccine for the prophylaxis of humans in...
Pathogens, Vol. 8, Pages 280: A Dual Role for Macrophages in Modulating Lung Tissue Damage/Repair during L2 Toxocara canis Infection Pathogens doi: 10.3390/pathogens8040280 Authors: Berenice Faz-López Héctor Mayoral-Reyes Rogelio Hernández-Pando Pablo Martínez-Labat Derek M. McKay Itzel Medina-Andrade Jonadab E. Olguín Luis I. Terrazas Macrophages that are classically activated (M1) through the IFN-γ/STAT1 signaling pathway have a major role in mediating...
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Pharmaceuticals, Vol. 12, Pages 176: In Vitro Characterization and Stability Profiles of Antibody–Fluorophore Conjugates Derived from Interchain Cysteine Cross-Linking or Lysine Bioconjugation Pharmaceuticals doi: 10.3390/ph12040176 Authors: Martin Brachet Colas Allard-Vannier Kizlik-Masson Esnault Respaud Denevault-Sabourin Chourpa Gouilleux-Gruart Viaud-Massuard Joubert Fluorescent labelling of monoclonal antibodies (mAbs) is classically...
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Pharmaceutics, Vol. 11, Pages 643: Development of a Phosphoric Acid-Mediated Hyaluronic Acid Gel Sheet for Efficient Transdermal Delivery of Alendronate for Anti-Osteoporotic Therapy Pharmaceutics doi: 10.3390/pharmaceutics11120643 Authors: Naito Katsumi Yoneto Omura Nishidono Kamei Mizoguchi Tamba Tanaka Morishita Yamamoto For efficient transdermal delivery of alendronate (ALN) for anti-osteoporotic therapy, we developed a hyaluronic acid (HA)...
Pharmaceutics, Vol. 11, Pages 642: Targeting Human Thrombus by Liposomes Modified with Anti-Fibrin Protein Binders Pharmaceutics doi: 10.3390/pharmaceutics11120642 Authors: Petroková Mašek Kuchař Vítečková Wünschová Štikarová Bartheldyová Kulich Hubatka Kotouček Knotigová Vohlídalová Héžová Mašková Macaulay Dyr Raška Mikulík Malý Turánek Development of tools for direct thrombus imaging represents a key step for...
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Pharmacy, Vol. 7, Pages 162: Clinical Pharmacy Activities Documented (ClinPhADoc): Development, Reliability and Acceptability of a Documentation Tool for Community Pharmacists Pharmacy doi: 10.3390/pharmacy7040162 Authors: Hamada Quintana Bárcena Maes Bugnon Berger Documentation of community pharmacists’ clinical activities, such as the identification and management of drug-related problems (DRPs), is recommended. However, documentation is not systematic in...
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Plants, Vol. 8, Pages 565: Innovative RNAi Strategies and Tactics to Tackle Plum Pox Virus (PPV) Genome in Prunus domestica-Plum Plants doi: 10.3390/plants8120565 Authors: Ravelonandro Scorza Briard We developed an innovative RNAi concept based on two gene constructs built from the capsid gene (CP) cistron of the Plum pox virus (PPV) genome. First, designated as amiCPRNA, a potential molecule interfering with PPV genome translation and the second one is the ami-siCPRNA to target...
Plants, Vol. 8, Pages 564: Epigenetics Regulates Reproductive Development in Plants Plants doi: 10.3390/plants8120564 Authors: Qiang Han Arthur Bartels Xi Cheng Angela Meyer Yong-Qiang Charles An Tzung-Fu Hsieh Wenyan Xiao Seed, resulting from reproductive development, is the main nutrient source for human beings, and reproduction has been intensively studied through genetic, molecular, and epigenetic approaches. However, how different epigenetic pathways crosstalk...
Plants, Vol. 8, Pages 563: Faster Removal of 2-Phosphoglycolate through Photorespiration Improves Abiotic Stress Tolerance of Arabidopsis Plants doi: 10.3390/plants8120563 Authors: Stefan Timm Franziska Woitschach Carolin Heise Martin Hagemann Hermann Bauwe Photorespiration metabolizes 2-phosphoglyolate (2-PG) to avoid inhibition of carbon assimilation and allocation. In addition to 2-PG removal, photorespiration has been shown to play a role in stress protection. Here, we...
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Religions, Vol. 10, Pages 655: Introduction to “Religions in Shakespeare’s Writings” Religions doi: 10.3390/rel10120655 Authors: Urban This special issue of Religions on “Religions in Shakespeare’s Writings” invited contributors to explore the gamut of religious issues and characterizations throughout Shakespeare’s writings [...]
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Risks, Vol. 7, Pages 118: The Effect of Jumps in the Crude Oil Market on the Sovereign Risks of Major Oil Exporters Risks doi: 10.3390/risks7040118 Authors: Elie Bouri We study the jump behaviour in the sovereign risks of major oil-exporting countries and examine whether it is affected by jumps in the price and volatility of crude oil. Data used are daily from 14 February 2011, to 31 July 2019. We detect the presence of jumps in many oil exporters and find evidence of less frequent jumps...
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Social Sciences, Vol. 8, Pages 325: Introduction to Special Issue on Personal Essays in Social Science Social Sciences doi: 10.3390/socsci8120325 Authors: Pooja Sawrikar Donna McAuliffe I called this Special Issue because three of my own personal essays (Sawrikar 2018a, 2018b, 2018c) were rejected 18 times between them by scholarly journals. [...]
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Technologies, Vol. 7, Pages 83: Compensation for Geometrical Deviations in Additive Manufacturing Technologies doi: 10.3390/technologies7040083 Authors: Christoph Hartmann Philipp Lechner Benjamin Himmel Yannick Krieger Tim C. Lueth Wolfram Volk The design of additive manufacturing processes, especially for batch production in industrial practice, is of high importance for the propagation of new additive manufacturing technology. Manual redesign procedures of the additive...
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Toxins, Vol. 11, Pages 702: Immunogenic Properties of Recombinant Enzymes from Bothrops Ammodytoides Towards the Generation of Neutralizing Antibodies against Its Own Venom Toxins doi: 10.3390/toxins11120702 Authors: Clement Corrales-García Bolaños Corzo Villegas Bothropic venoms contain enzymes such as metalloproteases, serine-proteases, and phospholipases, which acting by themselves, or in synergism, are the cause of the envenomation symptoms and death. Here, two mRNA...
Toxins, Vol. 11, Pages 700: In-vitro Application of a Qatari Burkholderia cepacia strain (QBC03) in the Biocontrol of Mycotoxigenic Fungi and in the Reduction of Ochratoxin A biosynthesis by Aspergillus carbonarius Toxins doi: 10.3390/toxins11120700 Authors: Zeidan Ul-Hassan Al-Thani Migheli Jaoua Mycotoxins are secondary metabolites produced by certain filamentous fungi, causing human and animal health issues upon the ingestion of contaminated food and feed. Among...
Toxins, Vol. 11, Pages 701: Use of Competitive Filamentous Fungi as an Alternative Approach for Mycotoxin Risk Reduction in Staple Cereals: State of Art and Future Perspectives Toxins doi: 10.3390/toxins11120701 Authors: Sarrocco Mauro Battilani Among plant fungal diseases, those affecting cereals represent a huge problem in terms of food security and safety. Cereals, such as maize and wheat, are very often targets of mycotoxigenic fungi. The limited availability of chemical...
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Viruses, Vol. 11, Pages 1117: Ebola Virus Uptake into Polarized Cells from the Apical Surface Viruses doi: 10.3390/v11121117 Authors: Hu Wang Li Zhang Zhang Zhang Cui Ebola virus (EBOV) causes severe hemorrhagic fever with high mortality rates. EBOV can infect many types of cells. During severe EBOV infection, polarized epithelial and endothelial cells are damaged, which promotes vascular instability and dysregulation. However, the mechanism causing these symptoms...
Viruses, Vol. 11, Pages 1116: Crocodilepox Virus Evolutionary Genomics Supports Observed Poxvirus Infection Dynamics on Saltwater Crocodile (Crocodylus porosus) Viruses doi: 10.3390/v11121116 Authors: Sarker Isberg Moran Araujo Elliott Melville Beddoe Helbig Saltwater crocodilepox virus (SwCRV), belonging to the genus Crocodylidpoxvirus, are large DNA viruses posing an economic risk to Australian saltwater crocodile (Crocodylus porosus) farms by extending...
Viruses, Vol. 11, Pages 1115: Isolation and Characterization of a Novel Klebsiella pneumoniae N4-like Bacteriophage KP8 Viruses doi: 10.3390/v11121115 Authors: Morozova Babkin Kozlova Baykov Bokovaya Tikunov Ushakova Bardasheva Ryabchikova Zelentsova Tikunova Klebsiella pneumoniae is a common pathogen, associated with a wide spectrum of infections, and clinical isolates of K. pneumoniae often possess multiple antibiotic resistances. Here, we describe...
Viruses, Vol. 11, Pages 1114: Equine Mx1 Restricts Influenza A Virus Replication by Targeting at Distinct Site of its Nucleoprotein Viruses doi: 10.3390/v11121114 Authors: Fatima Zhang Zhang Wang Xu Chu Ji Wang Interferon-mediated host factors myxovirus (Mx) proteins are key features in regulating influenza A virus (IAV) infections. Viral polymerases are essential for viral replication. The Mx1 protein has been known to interact with viral nucleoprotein (NP)...
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Water, Vol. 11, Pages 2548: Evaluation of MAR Methods for Semi-Arid, Cold Regions Water doi: 10.3390/w11122548 Authors: Narantsogt Morhlok Mongolia is a semi-arid, highly continental region with highly variable precipitation andriver discharge. The groundwater aquifer located near Ulaanbaatar, the capital city of Mongolia, isthe only one source for city water supply consumption, and it is important to ensure thatgroundwater is available now and in the future. The main watercourse...
Water, Vol. 11, Pages 2547: North German Lowland Lakes Miss Ecological Water Quality Standards—A Lake Type Specific Analysis Water doi: 10.3390/w11122547 Authors: Rücker Nixdorf Quiel Grüneberg Despite great efforts in point source reductions due to improved wastewater treatment since 1990, more than 70% of the lakes in Germany have not yet achieved the “good ecological status” according to the European Water Framework Directive (WFD). To elicit lake...
Water, Vol. 11, Pages 2545: Effect of Urban Stormwater Road Runoff of Different Land Use Types on an Urban River in Shenzhen, China Water doi: 10.3390/w11122545 Authors: Liu Wang Yu Chen Du Qu Peng Zhang Gui Urban storm runoff is a major source of pollutants in receiving water bodies. To assess the impact of urban stormwater runoff on an urban river, the runoff process of total suspended solids (TSS), chemical oxygen demand (COD), ammonium (NH4), and...
Water, Vol. 11, Pages 2546: Water Footprint Assessment of Eggs in a Parent-Stock Layer Breeder Farm Water doi: 10.3390/w11122546 Authors: Xing Zheng Li Liu Zhang Egg production and consumption of eggs in China account for about 40% of the global total, and this constitutes a significant demand for water resources. The shortage of water resources in China means egg production in this country has serious water challenges. However, there are few studies concerning water...
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