Antibiotics, Vol. 9, Pages 677: Effect of Adjuvants on Oxytetracycline Uptake upon Foliar Application in Citrus Antibiotics doi: 10.3390/antibiotics9100677 Authors: Nabil Killiny Faraj Hijaz Pedro Gonzalez-Blanco Shelley E. Jones Myrtho O. Pierre Christopher I. Vincent Recently in Florida, foliar treatments using products with the antibiotics oxytetracyclineand streptomycin have been approved for the treatment of citrus Huanglongbing (HLB), which iscaused by the putative...
Tue Oct 06, 2020 03:00
Antibiotics, Vol. 9, Pages 676: Some Suggestions from PK/PD Principles to Contain Resistance in the Clinical Setting—Focus on ICU Patients and Gram-Negative Strains Antibiotics doi: 10.3390/antibiotics9100676 Authors: Chiara Adembri Andrea Novelli Stefania Nobili The containment of the phenomenon of resistance towards antimicrobials is a priority, especially in preserving molecules acting against Gram-negative pathogens, which represent the isolates more frequently found in the...
Tue Oct 06, 2020 03:00
Antibodies, Vol. 9, Pages 51: Anti gC1qR/p32/HABP1 Antibody Therapy Decreases Tumor Growth in an Orthotopic Murine Xenotransplant Model of Triple Negative Breast Cancer Antibodies doi: 10.3390/antib9040051 Authors: Ellinor I. Peerschke Elisa de Stanchina Qing Chang Katia Manova-Todorova Afsar Barlas Anne G. Savitt Brian V. Geisbrecht Berhane Ghebrehiwet gC1qR is highly expressed in breast cancer and plays a role in cancer cell proliferation. This study explored therapy...
Tue Oct 06, 2020 03:00
Antioxidants, Vol. 9, Pages 956: The Preventive Effects of Xanthohumol on Vascular Calcification Induced by Vitamin D3 Plus Nicotine Antioxidants doi: 10.3390/antiox9100956 Authors: Shu-Fen Liou Thi Tuyet Ngan Nguyen Jong-Hau Hsu Erna Sulistyowati Shang-En Huang Bin-Nan Wu Ming-Chung Lin Jwu-Lai Yeh Vascular calcification (VC) is highly prevalent in patients with atherosclerosis, chronic kidney disease, diabetes mellitus, and hypertension. In blood vessels, VC is...
Tue Oct 06, 2020 03:00
Antioxidants, Vol. 9, Pages 955: Colon Bioaccessibility under In Vitro Gastrointestinal Digestion of a Red Cabbage Extract Chemically Profiled through UHPLC-Q-Orbitrap HRMS Antioxidants doi: 10.3390/antiox9100955 Authors: Luana Izzo Yelko Rodríguez-Carrasco Severina Pacifico Luigi Castaldo Alfonso Narváez Alberto Ritieni Red cabbage is a native vegetable of the Mediterranean region that represents one of the major sources of anthocyanins. The aim of this research is to...
Tue Oct 06, 2020 03:00
Atmosphere, Vol. 11, Pages 1064: PlanetCARMA: A New Framework for Studying the Microphysics of Planetary Atmospheres Atmosphere doi: 10.3390/atmos11101064 Authors: Erika Barth The Community Aerosol and Radiation Model for Atmospheres (CARMA) has been updated to apply to atmospheres of the Solar System outside of Earth. CARMA, as its name suggests, is a coupled aerosol microphysics and radiative transfer model and includes the processes of nucleation, condensation, evaporation, coagulation,...
Tue Oct 06, 2020 03:00
Atmosphere, Vol. 11, Pages 1063: Comparison of Key Characteristics of Remarkable SSW Events in the Southern and Northern Hemisphere Atmosphere doi: 10.3390/atmos11101063 Authors: Michal Kozubek Jan Lastovicka Peter Krizan An exceptionally strong sudden stratospheric warming (SSW) in the Southern Hemisphere (SH) during September 2019 was observed. Because SSW in the SH is very rare, comparison with the only recorded major SH SSW is done. According to World Meteorological Organization...
Tue Oct 06, 2020 03:00
Atmosphere, Vol. 11, Pages 1062: High-Resolution COSMO-CLM Modeling and an Assessment of Mesoscale Features Caused by Coastal Parameters at Near-Shore Arctic Zones (Kara Sea) Atmosphere doi: 10.3390/atmos11101062 Authors: Vladimir Platonov Alexander Kislov Coastal Arctic regions are characterized by severe mesoscale weather events that include extreme wind speeds, and the rugged shore conditions, islands, and mountain ranges contribute to mesoscale event formation. High-resolution...
Tue Oct 06, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 153: African American College Students’ Drinking Behaviors and Their Relationship to Self-Efficacy and Positive or Negative Expectancies Regarding Alcohol Consumption Behavioral Sciences doi: 10.3390/bs10100153 Authors: Patrice R. Jenkins Pedro M. Hernandez Chaiqua A. Harris College students’ alcohol consumption remains a significant concern for colleges and universities. However, most research overwhelmingly utilizes White samples...
Tue Oct 06, 2020 03:00
Biology, Vol. 9, Pages 325: Machine Learning Model for Identifying Antioxidant Proteins Using Features Calculated from Primary Sequences Biology doi: 10.3390/biology9100325 Authors: Luu Ho Thanh Lam Ngoc Hoang Le Le Van Tuan Ho Tran Ban Truong Nguyen Khanh Hung Ngan Thi Kim Nguyen Luong Huu Dang Nguyen Quoc Khanh Le Antioxidant proteins are involved importantly in many aspects of cellular life activities. They protect the cell and DNA from oxidative substances (such...
Tue Oct 06, 2020 03:00
Biomedicines, Vol. 8, Pages 395: Humanization of Drosophila Gαo to Model GNAO1 Paediatric Encephalopathies Biomedicines doi: 10.3390/biomedicines8100395 Authors: Mikhail Savitsky Gonzalo P. Solis Mikhail Kryuchkov Vladimir L. Katanaev Several hundred genes have been identified to contribute to epilepsy—the disease affecting 65 million people worldwide. One of these genes is GNAO1 encoding Gαo, the major neuronal α-subunit of heterotrimeric G proteins....
Tue Oct 06, 2020 03:00
Biomedicines, Vol. 8, Pages 393: Questioning Cause and Effect: Children with Severe Asthma Exhibit High Levels of Inflammatory Biomarkers Including Beta-Hexosaminidase, but Low Levels of Vitamin A and Immunoglobulins Biomedicines doi: 10.3390/biomedicines8100393 Authors: Amali E. Samarasinghe Rhiannon R. Penkert Julia L. Hurwitz Robert E. Sealy Kim S. LeMessurier Catherine Hammond Patricia J. Dubin D. Betty Lew Asthma affects over 8% of the pediatric population in...
Tue Oct 06, 2020 03:00
Biomedicines, Vol. 8, Pages 394: Astrocytes: News about Brain Health and Diseases Biomedicines doi: 10.3390/biomedicines8100394 Authors: Jacopo Meldolesi Astrocytes, the most numerous glial cells in the brains of humans and other mammalian animals, have been studied since their discovery over 100 years ago. For many decades, however, astrocytes were believed to operate as a glue, providing only mechanical and metabolic support to adjacent neurons. Starting from a “revolution”...
Tue Oct 06, 2020 03:00
Biomolecules, Vol. 10, Pages 1413: Evolutionary Study of Disorder in Protein Sequences Biomolecules doi: 10.3390/biom10101413 Authors: Kristina Kastano Gábor Erdős Pablo Mier Gregorio Alanis-Lobato Vasilis J. Promponas Zsuzsanna Dosztányi Miguel A. Andrade-Navarro Intrinsically disordered proteins (IDPs) contain regions lacking intrinsic globular structure (intrinsically disordered regions, IDRs). IDPs are present across the tree of life, with great variability of IDR...
Tue Oct 06, 2020 03:00
Biomolecules, Vol. 10, Pages 1414: Changes in the Systemic Expression of Sirtuin-1 and Oxidative Stress after Intravitreal Anti-Vascular Endothelial Growth Factor in Patients with Retinal Vein Occlusion Biomolecules doi: 10.3390/biom10101414 Authors: Hwang Chang Lin Peng Chien Tsai Chen Chen Hsu Objectives: Retinal vein occlusions (RVO) are associated with systemic risk factors. However, the ocular occlusive events might also influence a patient’s...
Tue Oct 06, 2020 03:00
Biomolecules, Vol. 10, Pages 1412: Detection and Characterization of Antibacterial Siderophores Secreted by Endophytic Fungi from Cymbidium aloifolium Biomolecules doi: 10.3390/biom10101412 Authors: Srinivas Chowdappa Shubha Jagannath Narasimhamurthy Konappa Arakere C. Udayashankar Sudisha Jogaiah Endophytic fungi from orchid plants are reported to secrete secondary metabolites which include bioactive antimicrobial siderophores. In this study endophytic fungi capable of secreting...
Tue Oct 06, 2020 03:00
Biomolecules, Vol. 10, Pages 1411: Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate Biomolecules doi: 10.3390/biom10101411 Authors: Giacomo Parisi Ida Freda Cécile Exertier Cristina Cecchetti Elena Gugole Gabriele Cerutti Lucia D’Auria Alberto Macone Beatrice Vallone Carmelinda Savino Linda Celeste Montemiglio The cytochrome P450 OleP catalyzes the epoxidation of aliphatic carbons on both the aglycone 8.8a-deoxyoleandolide...
Tue Oct 06, 2020 03:00
Brain Sciences, Vol. 10, Pages 711: Alternative Microstructural Measures to Complement Diffusion Tensor Imaging in Migraine Studies with Standard MRI Acquisition Brain Sciences doi: 10.3390/brainsci10100711 Authors: Planchuelo-Gómez García-Azorín Guerrero Luis-García Rodríguez Aja-Fernández The white matter state in migraine has been investigated using diffusion tensor imaging (DTI) measures, but results using this technique are conflicting. To overcome DTI measures,...
Tue Oct 06, 2020 03:00
Brain Sciences, Vol. 10, Pages 710: Age-Dependent Auditory Processing Deficits after Cochlear Synaptopathy Depend on Auditory Nerve Latency and the Ability of the Brain to Recruit LTP/BDNF Brain Sciences doi: 10.3390/brainsci10100710 Authors: Philine Marchetta Daria Savitska Angelika Kübler Giulia Asola Marie Manthey Dorit Möhrle Thomas Schimmang Lukas Rüttiger Marlies Knipper Wibke Singer Age-related decoupling of auditory nerve fibers from hair cells (cochlear...
Tue Oct 06, 2020 03:00
Brain Sciences, Vol. 10, Pages 709: Tractography-Based Analysis of Morphological and Anatomical Characteristics of the Uncinate Fasciculus in Human Brains Brain Sciences doi: 10.3390/brainsci10100709 Authors: Sara Kierońska Paweł Sokal Marta Dura Magdalena Jabłońska Marcin Rudaś Renata Jabłońska (1) Background: The uncinate fasciculus (UF) is a white matter bundle connecting the prefrontal cortex and temporal lobe. The functional role of the uncinate fasciculus is still...
Tue Oct 06, 2020 03:00
Cancers, Vol. 12, Pages 2876: Blockage of Store-Operated Ca2+ Influx by Synta66 is Mediated by Direct Inhibition of the Ca2+ Selective Orai1 Pore Cancers doi: 10.3390/cancers12102876 Authors: Linda Waldherr Adela Tiffner Deepti Mishra Matthias Sallinger Romana Schober Irene Frischauf Tony Schmidt Verena Handl Peter Sagmeister Manuel Köckinger Isabella Derler Muammer Üçal Daniel Bonhenry Silke Patz Rainer Schindl The Ca2+ sensor STIM1 and the...
Tue Oct 06, 2020 03:00
Cancers, Vol. 12, Pages 2872: The Antidiabetic Agent Acarbose Improves Anti-PD-1 and Rapamycin Efficacy in Preclinical Renal Cancer Cancers doi: 10.3390/cancers12102872 Authors: Rachael M. Orlandella William J. Turbitt Justin T. Gibson Shannon K. Boi Peng Li Daniel L. Smith Lyse A. Norian Although immune checkpoint inhibitors and targeted therapeutics have changed the landscape of treatment for renal cell carcinoma (RCC), most patients do not experience significant...
Tue Oct 06, 2020 03:00
Cancers, Vol. 12, Pages 2874: DNA Repair Expression Profiling to Identify High-Risk Cytogenetically Normal Acute Myeloid Leukemia and Define New Therapeutic Targets Cancers doi: 10.3390/cancers12102874 Authors: Ludovic Gabellier Caroline Bret Guillaume Bossis Guillaume Cartron Jérôme Moreaux Cytogenetically normal acute myeloid leukemias (CN-AML) represent about 50% of total adult AML. Despite the well-known prognosis role of gene mutations such as NPM1 mutations of FLT3...
Tue Oct 06, 2020 03:00
Cancers, Vol. 12, Pages 2873: Association of Common Variants of TNFSF13 and TNFRSF13B Genes with CLL Risk and Clinical Picture, as Well as Expression of Their Products—APRIL and TACI Molecules Cancers doi: 10.3390/cancers12102873 Authors: Monika Jasek Agnieszka Bojarska-Junak Maciej Sobczyński Marta Wagner Sylwia Chocholska Jacek Roliński Dariusz Wołowiec Lidia Karabon Interactions between APRIL (TNFSF13) and its receptor TACI (TNFRSF13B) are implicated in providing...
Tue Oct 06, 2020 03:00
Cancers, Vol. 12, Pages 2871: High G2M Pathway Score Pancreatic Cancer is Associated with Worse Survival, Particularly after Margin-Positive (R1 or R2) Resection Cancers doi: 10.3390/cancers12102871 Authors: Masanori Oshi Stephanie Newman Yoshihisa Tokumaru Li Yan Ryusei Matsuyama Itaru Endo Matthew H.G. Katz Kazuaki Takabe Pancreatic cancer is highly mortal due to uncontrolled cell proliferation. The G2M checkpoint pathway is an essential part of the cell cycle....
Tue Oct 06, 2020 03:00
Cancers, Vol. 12, Pages 2875: Current Multimodality Treatments Against Brain Metastases from Renal Cell Carcinoma Cancers doi: 10.3390/cancers12102875 Authors: Yoshiyuki Matsui In patients with renal cell carcinoma, brain metastasis is generally one of the poor prognostic factors. However, the recent introduction of molecular target therapy and immune checkpoint inhibitor has remarkably advanced the systemic treatment of metastatic renal cell carcinoma and prolonged the patients’...
Tue Oct 06, 2020 03:00
Cancers, Vol. 12, Pages 2870: Tumor Microenvironment: Implications in Melanoma Resistance to Targeted Therapy and Immunotherapy Cancers doi: 10.3390/cancers12102870 Authors: Italia Falcone Fabiana Conciatori Chiara Bazzichetto Gianluigi Ferretti Francesco Cognetti Ludovica Ciuffreda Michele Milella Antitumor therapies have made great strides in recent decades. Chemotherapy, aggressive and unable to discriminate cancer from healthy cells, has given way to personalized...
Tue Oct 06, 2020 03:00
Cancers, Vol. 12, Pages 2869: Pterostilbene Sensitizes Cisplatin-Resistant Human Bladder Cancer Cells with Oncogenic HRAS Cancers doi: 10.3390/cancers12102869 Authors: Yi-Ting Chen Zi-Yi Huang Han-Hsuan Tang Wan-Ting Kuo Shan-Ying Wu Sheng-Hui Lan Kai-Hsun Chang Pin-Lun Lin Ming-Fen Lee Hung-Chi Cheng Hsiao-Sheng Liu Chi-Ying F. Huang Guan-Cheng Huang Chun-Li Su Analysis of various public databases revealed that HRAS gene mutation frequency and...
Tue Oct 06, 2020 03:00
Cancers, Vol. 12, Pages 2868: G-CSF and G-CSFR Induce a Pro-Tumorigenic Macrophage Phenotype to Promote Colon and Pancreas Tumor Growth Cancers doi: 10.3390/cancers12102868 Authors: Ioannis Karagiannidis Eliane de Santana Van Vilet Erika Said Abu Egal Brandon Phinney Damian Jacenik Eric R. Prossnitz Ellen J. Beswick Tumor-associated macrophages (TAMs) in the gastrointestinal tumor microenvironment (TME) are known to polarize into populations exhibiting pro- or anti-tumoral...
Tue Oct 06, 2020 03:00
Cancers, Vol. 12, Pages 2867: Testis Sparing Surgery in Pediatric Testicular Tumors Cancers doi: 10.3390/cancers12102867 Authors: Cezanne D. Kooij Caroline C.C. Hulsker Mariëtte E.G. Kranendonk József Zsiros Annemieke S. Littooij Leendert H.J. Looijenga Aart J. Klijn Annelies M.C. Mavinkurve-Groothuis Objective: The purpose of this review is to evaluate the outcomes of testis sparing surgery (TSS) and to investigate under which circumstances TSS can be considered...
Tue Oct 06, 2020 03:00
Cells, Vol. 9, Pages 2246: Protein O-GlcNAcylation Promotes Trophoblast Differentiation at Implantation Cells doi: 10.3390/cells9102246 Authors: Ruane Tan Adlam Kimber Brison Aplin Westwood Embryo implantation begins with blastocyst trophectoderm (TE) attachment to the endometrial epithelium, followed by the breaching of this barrier by TE-derived trophoblast. Dynamic protein modification with O-linked β-N-acetylglucosamine (O-GlcNAcylation) is mediated...
Tue Oct 06, 2020 03:00
Cells, Vol. 9, Pages 2244: Playing Jekyll and Hyde—The Dual Role of Lipids in Fatty Liver Disease Cells doi: 10.3390/cells9102244 Authors: Martijn R. Molenaar Louis C. Penning J. Bernd Helms Lipids play Jekyll and Hyde in the liver. On the one hand, the lipid-laden status of hepatic stellate cells is a hallmark of healthy liver. On the other hand, the opposite is true for lipid-laden hepatocytes—they obstruct liver function. Neglected lipid accumulation in hepatocytes...
Tue Oct 06, 2020 03:00
Cells, Vol. 9, Pages 2243: Long-Term Low-Dose Delta-9-Tetrahydrocannbinol (THC) Administration to Simian Immunodeficiency Virus (SIV) Infected Rhesus Macaques Stimulates the Release of Bioactive Blood Extracellular Vesicles (EVs) that Induce Divergent Structural Adaptations and Signaling Cues Cells doi: 10.3390/cells9102243 Authors: Yuan Lyu Steven Kopcho Mahesh Mohan Chioma M. Okeoma Blood extracellular vesicles (BEVs) carry bioactive cargo (proteins, genetic materials, lipids,...
Tue Oct 06, 2020 03:00
Cells, Vol. 9, Pages 2245: Involvement of Actin and Actin-Binding Proteins in Carcinogenesis Cells doi: 10.3390/cells9102245 Authors: Magdalena Izdebska Wioletta Zielińska Marta Hałas-Wiśniewska Alina Grzanka The actin cytoskeleton plays a crucial role in many cellular processes while its reorganization is important in maintaining cell homeostasis. However, in the case of cancer cells, actin and ABPs (actin-binding proteins) are involved in all stages of carcinogenesis. Literature...
Tue Oct 06, 2020 03:00
Cells, Vol. 9, Pages 2242: A Zebrafish Model of Retinitis Pigmentosa Shows Continuous Degeneration and Regeneration of Rod Photoreceptors Cells doi: 10.3390/cells9102242 Authors: Abirami Santhanam Eyad Shihabeddin Joshua A. Atkinson Duc Nguyen Ya-Ping Lin John O’Brien More than 1.5 million people suffer from Retinitis Pigmentosa, with many experiencing partial to complete vision loss. Regenerative therapies offer some hope, but their development is challenged by the limited...
Tue Oct 06, 2020 03:00
Children, Vol. 7, Pages 171: Non-Contact Video-Based Neonatal Respiratory Monitoring Children doi: 10.3390/children7100171 Authors: Scott L. Rossol Jeffrey K. Yang Caroline Toney-Noland Janine Bergin Chandan Basavaraju Pavan Kumar Henry C. Lee Respiratory rate (RR) has been shown to be a reliable predictor of cardio-pulmonary deterioration, but standard RR monitoring methods in the neonatal intensive care units (NICU) with contact leads have been related to iatrogenic...
Tue Oct 06, 2020 03:00
Children, Vol. 7, Pages 170: Preschool Teachers’ Beliefs towards Children with Autism Spectrum Disorder (ASD) in Yemen Children doi: 10.3390/children7100170 Authors: Sahar Mohammed Taresh Nor Aniza Ahmad Samsilah Roslan Aini Marina Ma’rof It is perplexing that some preschool teachers not only advise parents who have children with autism spectrum disorder (ASD) to go to religious healers, but also attribute such neurological disorders to the curse of the “evil eye”...
Tue Oct 06, 2020 03:00
Clean Technol., Vol. 2, Pages 406-421: Development of a Low-Cost Experimental Procedure for the Production of Laboratory Samples of Torrefied Biomass Clean Technologies doi: 10.3390/cleantechnol2040025 Authors: Leonel J. R. Nunes Jorge M. C. Ribeiro Letícia C. R. Sá Liliana M. E. F. Loureiro Radu Godina João C. O. Matias Currently, the search for alternative sources of energy is not only due to the scarcity of non-renewable sources, since these still have an availability...
Tue Oct 06, 2020 03:00
Clean Technol., Vol. 2, Pages 392-405: Evaluating the Emissions of the Heat Supplied by District Heating Networks through A Life Cycle Perspective Clean Technologies doi: 10.3390/cleantechnol2040024 Authors: Francesco Neirotti Michel Noussan Marco Simonetti The Life Cycle Assessment methodology has proven to be effective in evaluating the impacts of goods production throughout their life cycle. While many studies are available on specific products, in recent years a growing interest...
Tue Oct 06, 2020 03:00
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