IJMS, Vol. 21, Pages 7304: A Perspective on Therapeutic Pan-Resistance in Metastatic Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21197304 Authors: Dimitrios Korentzelos Amanda M. Clark Alan Wells Metastatic spread represents the leading cause of disease-related mortality among cancer patients. Many cancer patients suffer from metastatic relapse years or even decades after radical surgery for the primary tumor. This clinical phenomenon is explained by the...
Sat Oct 03, 2020 03:00
IJMS, Vol. 21, Pages 7302: Role of Neuroendocrine, Immune, and Autonomic Nervous System in Anorexia Nervosa-Linked Cardiovascular Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21197302 Authors: Nikola Sekaninova Lucia Bona Olexova Zuzana Visnovcova Igor Ondrejka Ingrid Tonhajzerova Anorexia nervosa represents a severe mental disorder associated with food avoidance and malnutrition. In patients suffering from anorexia nervosa, cardiovascular complications...
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7303: Enhanced Cycling Performance of Rechargeable Zinc–Air Flow Batteries Using Potassium Persulfate as Electrolyte Additive International Journal of Molecular Sciences doi: 10.3390/ijms21197303 Authors: Ramin Khezri Soraya Hosseini Abhishek Lahiri Shiva Rezaei Motlagh Mai Thanh Nguyen Tetsu Yonezawa Soorathep Kheawhom Zinc–air batteries (ZABs) offer high specific energy and low-cost production. However, rechargeable ZABs suffer from...
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7301: Preconditioned and Genetically Modified Stem Cells for Myocardial Infarction Treatment International Journal of Molecular Sciences doi: 10.3390/ijms21197301 Authors: Kamila Raziyeva Aiganym Smagulova Yevgeniy Kim Saltanat Smagul Ayan Nurkesh Arman Saparov Ischemic heart disease and myocardial infarction remain leading causes of mortality worldwide. Existing myocardial infarction treatments are incapable of fully repairing and regenerating the...
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7299: The Effects of Immune System Modulation on Prion Disease Susceptibility and Pathogenesis International Journal of Molecular Sciences doi: 10.3390/ijms21197299 Authors: Neil A. Mabbott Barry M. Bradford Reiss Pal Rachel Young David S. Donaldson Prion diseases are a unique group of infectious chronic neurodegenerative disorders to which there are no cures. Although prion infections do not stimulate adaptive immune responses in infected individuals,...
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7300: Adenosine Metabolism in the Cerebral Cortex from Several Mice Models during Aging International Journal of Molecular Sciences doi: 10.3390/ijms21197300 Authors: Alejandro Sánchez-Melgar José Luis Albasanz Mercè Pallàs Mairena Martín Adenosine is a neuromodulator that has been involved in aging and neurodegenerative diseases as Alzheimer’s disease (AD). In the present work, we analyzed the possible modulation of purine metabolites, 5’nucleotidase...
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7298: Quantitative Synaptic Biology: A Perspective on Techniques, Numbers and Expectations International Journal of Molecular Sciences doi: 10.3390/ijms21197298 Authors: Sofiia Reshetniak Rubén Fernández-Busnadiego Marcus Müller Silvio O. Rizzoli Christian Tetzlaff Synapses play a central role for the processing of information in the brain and have been analyzed in countless biochemical, electrophysiological, imaging, and computational studies. The functionality...
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7292: The Progression of Hemophilic Arthropathy: The Role of Biomarkers International Journal of Molecular Sciences doi: 10.3390/ijms21197292 Authors: Gianluigi Pasta Salvatore Annunziata Alberto Polizzi Laura Caliogna Eugenio Jannelli Alessandro Minen Mario Mosconi Francesco Benazzo Matteo Nicola Dario Di Minno Background: Hemophilia A and B are X-linked congenital bleeding disorders characterized by recurrent hemarthroses leading to specific...
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7296: Transcriptomic Analysis and Specific Expression of Transcription Factor Genes in the Root and Sporophyll of Dryopteris fragrans (L.) Schott International Journal of Molecular Sciences doi: 10.3390/ijms21197296 Authors: Lingling Chen Dongrui Zhang Chunhua Song Hemeng Wang Xun Tang Ying Chang Background: Dryopteris fragrans, which is densely covered with glandular trichomes, is considered to be one of the ferns with the most medicinal potential....
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7297: Effects of Fluoride Long-Term Exposure over the Cerebellum: Global Proteomic Profile, Oxidative Biochemistry, Cell Density, and Motor Behavior Evaluation International Journal of Molecular Sciences doi: 10.3390/ijms21197297 Authors: Géssica Oliveira Lopes Maria Karolina Martins Ferreira Lodinikki Davis Leonardo Oliveira Bittencourt Walessa Alana Bragança Aragão Aline Dionizio Marília Afonso Rabelo Buzalaf Maria Elena Crespo-Lopez Cristiane...
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7294: Inhibition of Orbivirus Replication by Aurintricarboxylic Acid International Journal of Molecular Sciences doi: 10.3390/ijms21197294 Authors: Celia Alonso Sergio Utrilla-Trigo Eva Calvo-Pinilla Luis Jiménez-Cabello Javier Ortego Aitor Nogales Bluetongue virus (BTV) and African horse sickness virus (AHSV) are vector-borne viruses belonging to the Orbivirus genus, which are transmitted between hosts primarily by biting midges of the genus Culicoides....
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7293: The Roles of SPOP in DNA Damage Response and DNA Replication International Journal of Molecular Sciences doi: 10.3390/ijms21197293 Authors: Masashi Maekawa Shigeki Higashiyama Speckle-type BTB/POZ protein (SPOP) is a substrate recognition receptor of the cullin-3 (CUL3)/RING type ubiquitin E3 complex. To date, approximately 30 proteins have been identified as ubiquitinated substrates of the CUL3/SPOP complex. Pathologically, missense mutations in the substrate-binding...
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7295: Role of Human Leukocyte Antigen System as A Predictive Biomarker for Checkpoint-Based Immunotherapy in Cancer Patients International Journal of Molecular Sciences doi: 10.3390/ijms21197295 Authors: Sabbatino Liguori Polcaro Salvato Caramori Salzano Casolaro Stellato Col Pepe Recent advances in cancer immunotherapy have clearly shown that checkpoint-based immunotherapy is effective in a small subgroup of cancer patients....
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7291: Diverse Physiological Functions and Regulatory Mechanisms for Signal-Transducing Small GTPases International Journal of Molecular Sciences doi: 10.3390/ijms21197291 Authors: Takaya Satoh Diverse GTPases act as signal transducing enzymes in a variety of organisms and cell types [...]
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7289: Cytosolic Sensors for Pathogenic Viral and Bacterial Nucleic Acids in Fish International Journal of Molecular Sciences doi: 10.3390/ijms21197289 Authors: Miriam Mojzesz Krzysztof Rakus Magdalena Chadzinska Kentaro Nakagami Gouranga Biswas Masahiro Sakai Jun-ichi Hikima Recognition of the non-self signature of invading pathogens is a crucial step for the initiation of the innate immune mechanisms of the host. The host response to viral and...
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7290: Retinal Degeneration and Alzheimer’s Disease: An Evolving Link International Journal of Molecular Sciences doi: 10.3390/ijms21197290 Authors: Ajay Ashok Neena Singh Suman Chaudhary Vindhya Bellamkonda Alexander E. Kritikos Aaron S. Wise Neil Rana Dallas McDonald Rithvik Ayyagari Age-related macular degeneration (AMD) and glaucoma are degenerative conditions of the retina and a significant cause of irreversible blindness in developed...
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7287: MiRNAs as Noninvasive Biomarkers and Therapeutic Agents of Pituitary Adenomas International Journal of Molecular Sciences doi: 10.3390/ijms21197287 Authors: Ozal Beylerli Narasimha M. Beeraka Ilgiz Gareev Valentin Pavlov Guang Yang Yanchao Liang Gjumrakch Aliev Pituitary adenoma (PA) accounts for 10–15% of all intracranial neoplasms. Even though most pituitary adenomas are benign, it is known that almost 35% of them exhibit an aggressive...
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7288: Pathway Analysis of Selected Circulating miRNAs in Plasma of Breast Cancer Patients: A Preliminary Study International Journal of Molecular Sciences doi: 10.3390/ijms21197288 Authors: Veronika Holubekova Zuzana Kolkova Marian Grendar Dusan Brany Dana Dvorska Igor Stastny Marianna Jagelkova Katarina Zelinova Marek Samec Alena Liskova Zuzana Laucekova Erik Kudela Martina Bobrovska Michal Kalman Pavol Zubor Zuzana Dankova...
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7286: Age- and Phenotype-Dependent Changes in Circulating MMP-2 and MMP-9 Activities in Normotensive and Hypertensive Rats International Journal of Molecular Sciences doi: 10.3390/ijms21197286 Authors: Marta Kollarova Angelika Puzserova Peter Balis Dominika Radosinska Lubomira Tothova Monika Bartekova Miroslav Barancik Jana Radosinska Matrix metalloproteinases (MMPs) are important in the pathogenesis of numerous diseases. The present study aimed...
Fri Oct 02, 2020 03:00
IJMS, Vol. 21, Pages 7285: Insights into Species Preservation: Cryobanking of Rabbit Somatic and Pluripotent Stem Cells International Journal of Molecular Sciences doi: 10.3390/ijms21197285 Authors: Lucie Gavin-Plagne Florence Perold Pierre Osteil Sophie Voisin Synara Cristina Moreira Quitterie Combourieu Véronique Saïdou Magali Mure Gérard Louis Anne Baudot Samuel Buff Thierry Joly Marielle Afanassieff Induced pluripotent stem cells (iPSCs) are obtained...
Fri Oct 02, 2020 03:00
JCDD, Vol. 7, Pages 42: Embryonic Mouse Cardiodynamic OCT Imaging Journal of Cardiovascular Development and Disease doi: 10.3390/jcdd7040042 Authors: Andrew L. Lopez Shang Wang Irina V. Larina The embryonic heart is an active and developing organ. Genetic studies in mouse models have generated great insight into normal heart development and congenital heart defects, and suggest mechanical forces such as heart contraction and blood flow to be implicated in cardiogenesis and disease....
Sun Oct 04, 2020 03:00
JCDD, Vol. 7, Pages 41: Cauterization as a Simple Method for Regeneration Studies in the Zebrafish Heart Journal of Cardiovascular Development and Disease doi: 10.3390/jcdd7040041 Authors: Papa K. Van Dyck Natasha Hockaden Emma C. Nelson Alyssa R. Koch Kamil L. Hester Neil Pillai Gabrielle C. Coffing Alan R. Burns Pascal J. Lafontant In the last two decades, the zebrafish has emerged as an important model species for heart regeneration studies. Various approaches...
Sat Oct 03, 2020 03:00
JCM, Vol. 9, Pages 3206: Physical Activity in 6.5-Year-Old Children Born Extremely Preterm Journal of Clinical Medicine doi: 10.3390/jcm9103206 Authors: Jenny Svedenkrans Örjan Ekblom Magnus Domellöf Vineta Fellman Mikael Norman Kajsa Bohlin Physical activity (PA) can prevent cardiovascular diseases. Because of increased risks of impairments affecting motor activity, PA in children born preterm may differ from that in children born at term. In this prospective cohort study,...
Sun Oct 04, 2020 03:00
JCM, Vol. 9, Pages 3205: Relationship between Apical Periodontitis and Metabolic Syndrome and Cardiovascular Events: A Cross-Sectional Study Journal of Clinical Medicine doi: 10.3390/jcm9103205 Authors: Beatriz González-Navarro Juan José Segura-Egea Albert Estrugo-Devesa Xavier Pintó-Sala Enric Jane-Salas Mari Carmen Jiménez-Sánchez Daniel Cabanillas-Balsera José López-López Aim: Both apical periodontitis (AP) and metabolic syndrome (MetS) are associated with atherosclerotic...
Sun Oct 04, 2020 03:00
JCM, Vol. 9, Pages 3204: Systemic Urate Deposition: An Unrecognized Complication of Gout? Journal of Clinical Medicine doi: 10.3390/jcm9103204 Authors: Puja Khanna Richard J. Johnson Bradley Marder Brian LaMoreaux Ada Kumar Gout, an inflammatory arthritis, affects over nine million people in the US with increasing prevalence. Some medical societies do not recommend treating gout unless it is recurrent. While soft tissue urate deposits (tophi), resultant bone erosions, and...
Sat Oct 03, 2020 03:00
JCM, Vol. 9, Pages 3203: Association between Hemiarthroplasty vs Total Hip Arthroplasty and Major Surgical Complications among Patients with Femoral Neck Fracture Journal of Clinical Medicine doi: 10.3390/jcm9103203 Authors: Takahisa Ogawa Toshitaka Yoshii Mutsuko Moriwaki Shingo Morishita Yoto Oh Kazumasa Miyatake Ara Nazarian Koichiro Shiba Atsushi Okawa Kiyohide Fushimi Takeo Fujiwara Previous studies have shown better clinical outcomes after total hip...
Sat Oct 03, 2020 03:00
JCM, Vol. 9, Pages 3202: Independent Predictors of Mortality in Torso Trauma Injuries Journal of Clinical Medicine doi: 10.3390/jcm9103202 Authors: Roberto Bini Caterina Accardo Stefano Granieri Fabrizio Sammartano Stefania Cimbanassi Federica Renzi Francesca Bindi Laura Briani Osvaldo Chiara Noncompressible torso injuries (NCTIs) represent a trauma-related condition with high lethality. This study’s aim was to identify potential prediction factors of...
Sat Oct 03, 2020 03:00
JCM, Vol. 9, Pages 3201: Circulating Soluble Urokinase-Type Plasminogen Activator Receptor Levels Reflect Renal Function in Newly Diagnosed Patients with Multiple Myeloma Treated with Bortezomib-Based Induction Journal of Clinical Medicine doi: 10.3390/jcm9103201 Authors: Evangelos Terpos Ioannis Ntanasis-Stathopoulos Gerasimos-Petros Papassotiriou Efstathios Kastritis Alexandra Margeli Nikolaos Kanellias Evangelos Eleutherakis-Papaiakovou Magdalini Migkou Despina Fotiou...
Sat Oct 03, 2020 03:00
JCM, Vol. 9, Pages 3199: The Association Between Delivery of Small-for-Gestational-Age Neonate and Their Risk for Long-Term Neurological Morbidity Journal of Clinical Medicine doi: 10.3390/jcm9103199 Authors: Hadar Sheiner Wainstock Small-for-gestational-age (SGA) is defined as a birth weight below the 10th or below the 5th percentile for a specific gestational age and sex. Previous studies have demonstrated an association between SGA neonates and long-term pediatric morbidity....
Fri Oct 02, 2020 03:00
JCM, Vol. 9, Pages 3198: Resting-State Functional Connectivity and Scholastic Performance in Preadolescent Children: A Data-Driven Multivoxel Pattern Analysis (MVPA) Journal of Clinical Medicine doi: 10.3390/jcm9103198 Authors: Daniel R. Westfall Sheeba A. Anteraper Laura Chaddock-Heyman Eric S. Drollette Lauren B. Raine Susan Whitfield-Gabrieli Arthur F. Kramer Charles H. Hillman Scholastic performance is the key metric by which schools measure student’s...
Fri Oct 02, 2020 03:00
JCM, Vol. 9, Pages 3200: The Quality of Life and Psychosocial Implications of Cancer-Related Lower-Extremity Lymphedema: A Systematic Review of the Literature Journal of Clinical Medicine doi: 10.3390/jcm9103200 Authors: Bowman Piedalue Baydoun Carlson Lower-extremity lymphedema (LEL) is a progressive, lifelong complication of cancer that places a substantial burden upon cancer survivors’ quality of life (QOL) and psychosocial well-being. Despite its prevalence,...
Fri Oct 02, 2020 03:00
JCM, Vol. 9, Pages 3197: The Impact of Virtual Reality Training on the Quality of Real Antromastoidectomy Performance Journal of Clinical Medicine doi: 10.3390/jcm9103197 Authors: Wojciech Gawęcki Magdalena Węgrzyniak Patrycja Mickiewicz Maria Bratumiła Gawłowska Marcin Talar Małgorzata Wierzbicka Background: The aim of this paper is to analyze the results of virtual reality (VR) antromastoidectomy simulation training and the transferability of the obtained skills to real...
Fri Oct 02, 2020 03:00
JCM, Vol. 9, Pages 3196: Whole Ovary Cryopreservation and Transplantation: A Systematic Review of Challenges and Research Developments in Animal Experiments and Humans Journal of Clinical Medicine doi: 10.3390/jcm9103196 Authors: Camille Hossay Jacques Donnez Marie-Madeleine Dolmans Ovarian tissue cryopreservation and transplantation is the only fertility preservation option that enables both restoration of fertility and resumption of ovarian endocrine function, avoiding the morbidity...
Fri Oct 02, 2020 03:00
JDB, Vol. 8, Pages 22: Exploring the Expression of Cardiac Regulators in a Vertebrate Extremophile: The Cichlid Fish Oreochromis (Alcolapia) alcalica Journal of Developmental Biology doi: 10.3390/jdb8040022 Authors: Gemma Sutton Lewis J. White Antonia G.P. Ford Asilatu Shechonge Julia J. Day Kanchon K. Dasmahapatra Mary E. Pownall Although it is widely accepted that the cellular and molecular mechanisms of vertebrate cardiac development are evolutionarily conserved,...
Sun Oct 04, 2020 03:00
JFB, Vol. 11, Pages 73: Hierarchical Surface Texturing of Hydroxyapatite Ceramics: Influence on the Adhesive Bonding Strength of Polymeric Polycaprolactone Journal of Functional Biomaterials doi: 10.3390/jfb11040073 Authors: Jonas Biggemann Philipp Müller David Köllner Swantje Simon Patrizia Hoffmann Paula Heik Jung Heon Lee Tobias Fey The tailored manipulation of ceramic surfaces gained recent interest to optimize the performance and lifetime of composite materials...
Sat Oct 03, 2020 03:00
JoF, Vol. 6, Pages 206: Fungi–Nematode Interactions: Diversity, Ecology, and Biocontrol Prospects in Agriculture Journal of Fungi doi: 10.3390/jof6040206 Authors: Ying Zhang Shuoshuo Li Haixia Li Ruirui Wang Ke-Qin Zhang Jianping Xu Fungi and nematodes are among the most abundant organisms in soil habitats. They provide essential ecosystem services and play crucial roles for maintaining the stability of food-webs and for facilitating nutrient cycling. As two of the very...
Sun Oct 04, 2020 03:00
JoF, Vol. 6, Pages 205: Landscape Connectivity Limits the Predicted Impact of Fungal Pathogen Invasion Journal of Fungi doi: 10.3390/jof6040205 Authors: Zhimin Li An Martel Sergé Bogaerts Bayram Göçmen Panayiotis Pafilis Petros Lymberakis Tonnie Woeltjes Michael Veith Frank Pasmans Infectious diseases are major drivers of biodiversity loss. The risk of fungal diseases to the survival of threatened animals in nature is determined by a complex interplay between...
Sat Oct 03, 2020 03:00
JoF, Vol. 6, Pages 204: Chromoblastomycosis in an Endemic Area of Brazil: A Clinical-Epidemiological Analysis and a Worldwide Haplotype Network Journal of Fungi doi: 10.3390/jof6040204 Authors: Daniel Wagner C. L. Santos Vania Aparecida Vicente Vinicius Almir Weiss G. Sybren de Hoog Renata R. Gomes Edith M. M. Batista Sirlei Garcia Marques Flávio de Queiroz-Telles Arnaldo Lopes Colombo Conceição de Maria Pedrozo e Silva de Azevedo Chromoblastomycosis (CBM)...
Sat Oct 03, 2020 03:00
JoF, Vol. 6, Pages 203: A Novel Secreted Cysteine-Rich Anionic (Sca) Protein from the Citrus Postharvest Pathogen Penicillium digitatum Enhances Virulence and Modulates the Activity of the Antifungal Protein B (AfpB) Journal of Fungi doi: 10.3390/jof6040203 Authors: Garrigues Marcos Manzanares Gandía Antifungal proteins (AFPs) from ascomycete fungi could help the development of antimycotics. However, little is known about their biological role or functional interactions...
Fri Oct 02, 2020 03:00
J. Imaging, Vol. 6, Pages 103: Fusion of External and Internal Prior Information for the Removal of Gaussian Noise in Images Journal of Imaging doi: 10.3390/jimaging6100103 Authors: Ali S. Awad In this paper, a new method for the removal of Gaussian noise based on two types of prior information is described. The first type of prior information is internal, based on the similarities between the pixels in the noisy image, and the other is external, based on the index or pixel location...
Sun Oct 04, 2020 03:00
JPM, Vol. 10, Pages 155: Radiation Biomarkers in Large Scale Human Health Effects Studies Journal of Personalized Medicine doi: 10.3390/jpm10040155 Authors: Jayne Moquet Kai Rothkamm Stephen Barnard Elizabeth Ainsbury Following recent developments, the RENEB network (Running the European Network of biological dosimetry and physical retrospective dosimetry) is in an excellent position to carry out large scale molecular epidemiological studies of ionizing radiation effects, with...
Sat Oct 03, 2020 03:00
JPM, Vol. 10, Pages 154: Establishment of a Pharmacogenetics Service Focused on Optimizing Existing Pharmacogenetic Testing at a Large Academic Health Center Journal of Personalized Medicine doi: 10.3390/jpm10040154 Authors: Amy L. Pasternak Kristen M. Ward Mohammad B. Ateya Hae Mi Choe Amy N. Thompson John S. Clark Vicki Ellingrod Multiple groups have described strategies for clinical implementation of pharmacogenetics (PGx) that often include internal laboratory tests...
Sat Oct 03, 2020 03:00
JPM, Vol. 10, Pages 151: The Genetics of Spondyloarthritis Journal of Personalized Medicine doi: 10.3390/jpm10040151 Authors: Roberto Díaz-Peña Patricia Castro-Santos Josefina Durán Catalina Santiago Alejandro Lucia The term spondyloarthritis (SpA) encompasses a group of chronic inflammatory diseases with common features in terms of clinical presentation and genetic predisposition. SpA is characterized by inflammation of the spine and peripheral joints, and is also be associated...
Fri Oct 02, 2020 03:00
JPM, Vol. 10, Pages 153: Thoracic Aortic Aneurysm and Factors Affecting Aortic Dissection Journal of Personalized Medicine doi: 10.3390/jpm10040153 Authors: Petr V. Chumachenko Anton Yu. Postnov Alexandra G. Ivanova Olga I. Afanasieva Maksim A. Afanasiev Mariam Bagheri Ekta Vasily N. Sukhorukov Grigoriy I. Kheimets Igor A. Sobenin This study is aimed at investigating the relationship between inflammation, the number of vasa vasorum, and the presence of lipoprotein...
Fri Oct 02, 2020 03:00
JPM, Vol. 10, Pages 152: Multivariate Analysis of Fecal Metabolites from Children with Autism Spectrum Disorder and Gastrointestinal Symptoms before and after Microbiota Transfer Therapy Journal of Personalized Medicine doi: 10.3390/jpm10040152 Authors: Fatir Qureshi James Adams Kathryn Hanagan Dae-Wook Kang Rosa Krajmalnik-Brown Juergen Hahn Fecal microbiota transplant (FMT) holds significant promise for patients with Autism Spectrum Disorder (ASD) and gastrointestinal...
Fri Oct 02, 2020 03:00
Life, Vol. 10, Pages 230: Plasma Long Noncoding RNA LeXis is a Potential Diagnostic Marker for Non-Alcoholic Steatohepatitis Life doi: 10.3390/life10100230 Authors: Jung Gil Park Gyeonghwa Kim Se Young Jang Yu Rim Lee Eunhye Lee Hye Won Lee Man-Hoon Han Jae Min Chun Young Seok Han Jun Sik Yoon Min Kyu Kang Young Oh Kweon Won Young Tak Soo Young Park Keun Hur Non-invasive diagnostic markers are needed to ease the diagnosis of non-alcoholic steatohepatitis...
Sat Oct 03, 2020 03:00
Life, Vol. 10, Pages 229: Whole Genome Sequencing and Comparative Genome Analysis of the Halotolerant Deep Sea Black Yeast Hortaea werneckii Life doi: 10.3390/life10100229 Authors: Orazio Romeo Alessia Marchetta Domenico Giosa Letterio Giuffrè Clara Urzì Filomena De Leo Hortaea werneckii, an extreme halotolerant black yeast in the order of Capnodiales, was recently isolated from different stations and depths in the Mediterranean Sea, where it was shown to be the dominant...
Fri Oct 02, 2020 03:00
Life, Vol. 10, Pages 228: The Application of Next-Generation Sequencing to Define Factors Related to Oral Cancer and Discover Novel Biomarkers Life doi: 10.3390/life10100228 Authors: Soyeon Kim Joo Won Lee Young-Seok Park Despite the introduction of next-generation sequencing in the realm of DNA sequencing technology, it is not often used in the investigation of oral squamous cell carcinoma (OSCC). Oral cancer is one of the most frequently occurring malignancies in some parts of...
Fri Oct 02, 2020 03:00
Medicina, Vol. 56, Pages 519: Ticagrelor as an Alternative Antiplatelet Therapy in Cardiac Patients Non-Sensitive to Aspirin Medicina doi: 10.3390/medicina56100519 Authors: Hamzah Khan Reid Gallant Shubha Jain Mohammed Al-Omran Charles De Mestral Elisa Greco Mark Wheatcroft Ashraf Alazonni Rawand Abdin Margaret L. Rand Heyu Ni Mohammad Qadura Background and Objectives: Aspirin (acetylsalicylic acid—ASA) is a first-line antiplatelet therapy provided...
Fri Oct 02, 2020 03:00
Medicina, Vol. 56, Pages 518: Computed Tomography Diagnostic of Uncommon Case of Osteopetrosis in 80-Year-Old Man—Case Report Medicina doi: 10.3390/medicina56100518 Authors: Witold Krupski Joanna Kruk-Bachonko Marcin R. Tatara Background and Objectives: During osteopetrosis course, impaired bone remodeling induces skeletal osteosclerosis and abnormally dense bones, which, however, are brittle and susceptible to low-energy fractures. In this study, radiological evaluation and densitometric...
Fri Oct 02, 2020 03:00
Medicina, Vol. 56, Pages 517: Safety and Efficacy of Nontuberculous Mycobacteria Treatment among Elderly Patients Medicina doi: 10.3390/medicina56100517 Authors: Yoshitaka Uchida Jiro Terada Tetsuya Homma Hatsuko Mikuni Kuniaki Hirai Haruhisa Saito Ryoichi Honda Hironori Sagara Background and objectives: Incidence rates of pulmonary nontuberculous mycobacterial (NTM) disease have been increasing, especially in the elderly population. Given the limited evidence regarding...
Fri Oct 02, 2020 03:00
Membranes, Vol. 10, Pages 274: Membranes for Modelling Cardiac Tissue Stiffness In Vitro Based on Poly(trimethylene carbonate) and Poly(ethylene glycol) Polymers Membranes doi: 10.3390/membranes10100274 Authors: Iris Allijn Marcelo Ribeiro André Poot Robert Passier Dimitrios Stamatialis Despite the increased expenditure of the pharmaceutical industry on research and development, the number of drugs for cardiovascular diseases that reaches the market is decreasing. A major...
Sat Oct 03, 2020 03:00
Membranes, Vol. 10, Pages 273: Vertically Aligned Carbon Nanotube Membranes: Water Purification and Beyond Membranes doi: 10.3390/membranes10100273 Authors: Jeong Hoon Lee Han-Shin Kim Eun-Tae Yun So-Young Ham Jeong-Hoon Park Chang Hoon Ahn Sang Hyup Lee Hee-Deung Park Vertically aligned carbon nanotube (VACNT) membranes have attracted significant attention for water purification owing to their ultra-high water permeability and antibacterial properties. In this paper,...
Fri Oct 02, 2020 03:00
Metabolites, Vol. 10, Pages 395: The Bioassay-Guided Fractionation and Identification of Potent Acetylcholinesterase Inhibitors from Narcissus c.v. ‘Hawera’ Using Optimized Vacuum Liquid Chromatography, High Resolution Mass Spectrometry and Bioautography Metabolites doi: 10.3390/metabo10100395 Authors: Tomasz Mroczek Aleksandra Dymek Jarosław Widelski Krzysztof Kamil Wojtanowski Bioassay-guided isolation of bioactive compound is a modern and efficient technique in metabolites...
Sun Oct 04, 2020 03:00
Metabolites, Vol. 10, Pages 394: Molecular Chaperones: Molecular Assembly Line Brings Metabolism and Immunity in Shape Metabolites doi: 10.3390/metabo10100394 Authors: Haoxin Zhao Lydia N. Raines Stanley Ching-Cheng Huang Molecular chaperones are a set of conserved proteins that have evolved to assist the folding of many newly synthesized proteins by preventing their misfolding under conditions such as elevated temperatures, hypoxia, acidosis and nutrient deprivation. Molecular...
Sat Oct 03, 2020 03:00
Metabolites, Vol. 10, Pages 393: BALSAM—An Interactive Online Platform for Breath Analysis, Visualization and Classification Metabolites doi: 10.3390/metabo10100393 Authors: Philipp Weber Josch Konstantin Pauling Markus List Jan Baumbach The field of breath analysis lacks a fully automated analysis platform that enforces machine learning good practice and enables clinicians and clinical researchers to rapidly and reproducibly discover metabolite patterns in diseases. We present...
Fri Oct 02, 2020 03:00
Metabolites, Vol. 10, Pages 392: Daily Use of Extra Virgin Olive Oil with High Oleocanthal Concentration Reduced Body Weight, Waist Circumference, Alanine Transaminase, Inflammatory Cytokines and Hepatic Steatosis in Subjects with the Metabolic Syndrome: A 2-Month Intervention Study Metabolites doi: 10.3390/metabo10100392 Authors: Angelo M. Patti Giuseppe Carruba Arrigo F. G. Cicero Maciej Banach Dragana Nikolic Rosaria V. Giglio Antonino Terranova Maurizio Soresi Lydia...
Fri Oct 02, 2020 03:00
Microorganisms, Vol. 8, Pages 1525: Proteotyping Environmental Microorganisms by Phylopeptidomics: Case Study Screening Water from a Radioactive Material Storage Pool Microorganisms doi: 10.3390/microorganisms8101525 Authors: Hayoun Pible Petit Allain Jouffret Culotta Rivasseau Armengaud Alpha-Bazin The microbial diversity encompassed by the environmental biosphere is largely unexplored, although it represents an extensive source of new knowledge and...
Sun Oct 04, 2020 03:00
Microorganisms, Vol. 8, Pages 1524: Antiviral Effects of Curcumin on Adenovirus Replication Microorganisms doi: 10.3390/microorganisms8101524 Authors: Morgan R. Jennings Robin J. Parks Human adenovirus (HAdV) is a common pathogen that can cause severe morbidity and mortality in certain populations, including pediatric, geriatric, and immunocompromised patients. Unfortunately, there are no approved therapeutics to combat HAdV infections. Curcumin, the primary curcuminoid compound found...
Sun Oct 04, 2020 03:00
Microorganisms, Vol. 8, Pages 1526: A New Endemic of Concomitant Nonalcoholic Fatty Liver Disease and Chronic Hepatitis B Microorganisms doi: 10.3390/microorganisms8101526 Authors: Hanif Khan Ali Shah Satiya Lau Aslam Hepatitis B virus (HBV) infection remains a global public problem despite the availability of an effective vaccine. In the past decades, nonalcoholic fatty liver disease (NAFLD) has surpassed HBV as the most common cause of chronic liver disease...
Sun Oct 04, 2020 03:00
Microorganisms, Vol. 8, Pages 1521: Vaccines against Meningococcal Diseases Microorganisms doi: 10.3390/microorganisms8101521 Authors: Pizza Bekkat-Berkani Rappuoli Neisseria meningitidis is the main cause of meningitis and sepsis, potentially life-threatening conditions. Thanks to advancements in vaccine development, vaccines are now available for five out of six meningococcal disease-causing serogroups (A, B, C, W, and Y). Vaccination programs with monovalent meningococcal...
Sat Oct 03, 2020 03:00
Microorganisms, Vol. 8, Pages 1523: In Sulfolobus solfataricus, the Poly(ADP-Ribose) Polymerase-Like Thermoprotein Is a Multifunctional Enzyme Microorganisms doi: 10.3390/microorganisms8101523 Authors: Anna De Maio Elena Porzio Sergio Rotondo Anna Rita Bianchi Maria Rosaria Faraone-Mennella In Sulfolobus solfataricus, Sso, the ADP-ribosylating thermozyme is known to carry both auto- and heteromodification of target proteins via short chains of ADP-ribose. Here, we provide...
Sat Oct 03, 2020 03:00
Microorganisms, Vol. 8, Pages 1522: Culturing Ancient Bacteria Carrying Resistance Genes from Permafrost and Comparative Genomics with Modern Isolates Microorganisms doi: 10.3390/microorganisms8101522 Authors: Pamela Afouda Grégory Dubourg Anthony Levasseur Pierre-Edouard Fournier Jeremy Delerce Oleg Mediannikov Seydina M. Diene Daniel Nahon Didier Bourlès Jean-Marc Rolain Didier Raoult Long considered to be a consequence of human antibiotics use by deduction,...
Sat Oct 03, 2020 03:00
Microorganisms, Vol. 8, Pages 1519: Long-Term Helicobacter pylori Infection Switches Gastric Epithelium Reprogramming Towards Cancer Stem Cell-Related Differentiation Program in Hp-Activated Gastric Fibroblast-TGFβ Dependent Manner Microorganisms doi: 10.3390/microorganisms8101519 Authors: Gracjana Krzysiek-Maczka Aneta Targosz Urszula Szczyrk Tomasz Wrobel Malgorzata Strzalka Tomasz Brzozowski Jaroslaw Czyz Agata Ptak-Belowska Helicobacter pylori (Hp)-induced inflammatory...
Fri Oct 02, 2020 03:00
Microorganisms, Vol. 8, Pages 1520: Genotypic and Phenotypic Characterization of Treponema phagedenis from Bovine Digital Dermatitis Microorganisms doi: 10.3390/microorganisms8101520 Authors: Hector M. Espiritu Lovelia L. Mamuad Su-jeong Jin Seon-ho Kim Seok-won Kwon Sang-suk Lee Sang-myeong Lee Yong-il Cho This study aimed to isolate and characterize Treponema spp. from bovine digital dermatitis (BDD)-infected dairy cattle. Seven isolates were characterized in this...
Fri Oct 02, 2020 03:00
Molecules, Vol. 25, Pages 4547: The Electric Field Responses of Inorganic Ionogels and Poly(ionic liquid)s Molecules doi: 10.3390/molecules25194547 Authors: Zhao Zhang Yin Dong Liu Ionic liquids (ILs) are a class of pure ions with melting points lower than 100 °C. They are getting more and more attention because of their high thermal stability, high ionic conductivity and dielectric properties. The unique dielectric properties aroused by the ion motion of ILs...
Sun Oct 04, 2020 03:00
Molecules, Vol. 25, Pages 4548: A Stable Coordination Polymer Based on Rod-Like Silver(I) Nodes with Contiguous Ag-S Bonding Molecules doi: 10.3390/molecules25194548 Authors: Betts Linder-Patton Sumby Silver(I)-based coordination polymers or metal-organic frameworks (MOFs) display useful antibacterial properties, whereby distinct materials with different bonding can afford control over the release of silver(I) ions. Such silver(I) materials are comprised of discrete secondary...
Sun Oct 04, 2020 03:00
Molecules, Vol. 25, Pages 4549: Regulation of Obesity by Antiangiogenic Herbal Medicines Molecules doi: 10.3390/molecules25194549 Authors: Shin Yoon Obesity is the result of an energy imbalance caused by an increased ratio of caloric intake to energy expenditure. In conjunction with obesity, related metabolic disorders, such as dyslipidemia, atherosclerosis, and type 2 diabetes, have become global health problems. Obesity progression is thought to be associated with angiogenesis...
Sun Oct 04, 2020 03:00
Molecules, Vol. 25, Pages 4546: Ethyne Functionalized Meso-Phenothiazinyl-Phenyl-Porphyrins: Synthesis and Optical Properties of Free Base Versus Protonated Species Molecules doi: 10.3390/molecules25194546 Authors: Eva Molnar Emese Gál Luiza Găină Castelia Cristea Luminița Silaghi-Dumitrescu Synthesis, structural characterization and photophysical properties for a series of new trans-A2B2- and A3B-type ethynyl functionalized meso-phenothiazinyl-phenyl porphyrin derivatives...
Sun Oct 04, 2020 03:00
Molecules, Vol. 25, Pages 4545: Potential Anti-Acetylcholinesterase Activity of Cassia timorensis DC. Molecules doi: 10.3390/molecules25194545 Authors: Nurul Amira Nurul Azman Maram B. Alhawarri Mira Syahfriena Amir Rawa Roza Dianita Amirah Mohd Gazzali Toshihiko Nogawa Habibah A. Wahab Seventeen methanol extracts from different plant parts of five different Cassia species, including C. timorensis, C. grandis, C. fistula, C. spectabilis, and C. alata were screened against...
Sun Oct 04, 2020 03:00
Molecules, Vol. 25, Pages 4544: The Self-Aggregation of Porphyrins with Multiple Chiral Centers in Organic/Aqueous Media: The Case of Sugar- and Steroid-Porphyrin Conjugates Molecules doi: 10.3390/molecules25194544 Authors: Manuela Stefanelli Federica Mandoj Gabriele Magna Raffaella Lettieri Mariano Venanzi Roberto Paolesse Donato Monti An overview of the solvent-driven aggregation of a series of chiral porphyrin derivatives studied by optical methods (UV/Vis, fluorescence,...
Sun Oct 04, 2020 03:00
Molecules, Vol. 25, Pages 4543: Volatile Compounds and Physicochemical Quality of Four Jabuticabas (Plinia sp.) Molecules doi: 10.3390/molecules25194543 Authors: Thais Pádua Freitas Isabela Barroso Taver Poliana Cristina Spricigo Lucas Bueno do Amaral Eduardo Purgatto Angelo Pedro Jacomino The jabuticaba is a native Brazilian fruit that has aroused worldwide interest in terms of its nutritional composition and biological activity. However, research on the profile of volatile...
Sat Oct 03, 2020 03:00
Molecules, Vol. 25, Pages 4541: Spectroscopic and In Vitro Investigations of Boron(III) Complex with Meso-4-Methoxycarbonylpropylsubstituted Dipyrromethene for Fluorescence Bioimaging Applications Molecules doi: 10.3390/molecules25194541 Authors: Galina Guseva Elena Antina Mikhail Berezin Svetlana Lisovskaya Roman Pavelyev Airat Kayumov Olga Lodochnikova Daut Islamov Konstantin Usachev Sergei Boichuk Liliya Nikitina This study focuses on the behavior of...
Sat Oct 03, 2020 03:00
Molecules, Vol. 25, Pages 4542: Cytochrome P450 Can Epoxidize an Oxepin to a Reactive 2,3-Epoxyoxepin Intermediate: Potential Insights into Metabolic Ring-Opening of Benzene Molecules doi: 10.3390/molecules25194542 Authors: Holly M. Weaver-Guevara Ryan W. Fitzgerald Noah A. Cote Arthur Greenberg Dimethyldioxirane epoxidizes 4,5-benzoxepin to form the reactive 2,3-epoxyoxepin intermediate followed by very rapid ring-opening to an o-xylylene that immediately isomerizes to the...
Sat Oct 03, 2020 03:00
Molecules, Vol. 25, Pages 4540: Synthesis, Characterisation and In Vitro Anticancer Activity of Catalytically Active Indole-Based Half-Sandwich Complexes Molecules doi: 10.3390/molecules25194540 Authors: Joan J. Soldevila-Barreda Kehinde B. Fawibe Maria Azmanova Laia Rafols Anaïs Pitto-Barry Uche B. Eke Nicolas P. E. Barry The synthesis, characterisation and evaluation of the in vitro cytotoxicity of four indole-based half-sandwich metal complexes towards two ovarian...
Sat Oct 03, 2020 03:00
Molecules, Vol. 25, Pages 4538: Polyphenol Composition and Antioxidant Potential of Instant Gruels Enriched with Lycium barbarum L. Fruit Molecules doi: 10.3390/molecules25194538 Authors: Olech Kasprzak Wójtowicz Oniszczuk Nowak Waksmundzka-Hajnos Combrzyński Gancarz Kowalska Krajewska Oniszczuk Goji fruit (Lycium barbarum L.) has been identified as a polyphenolic compound plant source of noted richness. It also contains polysaccharides, carotenoids,...
Sat Oct 03, 2020 03:00
Molecules, Vol. 25, Pages 4537: Glucosinolates: Natural Occurrence, Biosynthesis, Accessibility, Isolation, Structures, and Biological Activities Molecules doi: 10.3390/molecules25194537 Authors: Nguyen Stewart Lopez Ioannou Allais Glucosinolates (GSLs) are secondary plant metabolites abundantly found in plant order Brassicales. GSLs are constituted by an S-β-d-glucopyrano unit anomerically connected to O-sulfated (Z)-thiohydroximate moiety. The side-chain...
Sat Oct 03, 2020 03:00
Molecules, Vol. 25, Pages 4539: Design and Synthesis of a Chiral Halogen-Bond Donor with a Sp3-Hybridized Carbon–Iodine Moiety in a Chiral Fluorobissulfonyl Scaffold Molecules doi: 10.3390/molecules25194539 Authors: Uno Matsuzaki Shiro Shibata The first example of a chiral halogen-bond donor with a sp3-hybridized carbon–iodine moiety in a fluorobissulfonyl scaffold is described. The binaphthyl backbone was designed as a chiral source and the chiral halogen-bond...
Sat Oct 03, 2020 03:00
Molecules, Vol. 25, Pages 4535: Markovnikov-Type Hydrotrifluoromethylchalcogenation of Unactivated Terminal Alkenes with [Me4N][XCF3] (X = S, Se) and TfOH Molecules doi: 10.3390/molecules25194535 Authors: Jin Shi Cheng-Pan Zhang The first Markovnikov-type hydrotrifluoromethylselenolation of unactivated terminal alkenes with the readily accessible [Me4N][SeCF3] reagent and the superacid TfOH is reported. The reaction proceeded at room temperature under catalyst- and additive-free conditions...
Sat Oct 03, 2020 03:00
Molecules, Vol. 25, Pages 4536: Aluminium Binding to Modified Amyloid-β Peptides: Implications for Alzheimer’s Disease Molecules doi: 10.3390/molecules25194536 Authors: Mocanu Jureschi Drochioiu Aluminium (Al) is clearly neurotoxic and considerable evidence exists that Al may play a role in the aetiology or pathogenesis of Alzheimer’s disease (AD). Nevertheless, the link between AD pathology and Al is still open to debate. Therefore, we investigated here the interaction...
Sat Oct 03, 2020 03:00
Molecules, Vol. 25, Pages 4534: New Sustainable Process for Hesperidin Isolation and Anti-Ageing Effects of Hesperidin Nanocrystals Molecules doi: 10.3390/molecules25194534 Authors: Danijela Stanisic Leticia H. B. Liu Roney V. dos Santos Amanda F. Costa Nelson Durán Ljubica Tasic Hesperidin, a secondary orange (Citrus sinensis) metabolite, was extracted from orange bagasse. No organic solvents or additional energy consumption were used in the clean and sustainable process....
Sat Oct 03, 2020 03:00
Molecules, Vol. 25, Pages 4533: Transformed Shoots of Dracocephalum forrestii W.W. Smith from Different Bioreactor Systems as a Rich Source of Natural Phenolic Compounds Molecules doi: 10.3390/molecules25194533 Authors: Izabela Weremczuk-Jeżyna Paweł Lisiecki Weronika Gonciarz Łukasz Kuźma Magdalena Szemraj Magdalena Chmiela Izabela Grzegorczyk-Karolak Transformed shoots of the Tibetan medicinal plant Dracocephalum forrestii were cultured in temporary immersion bioreactors...
Sat Oct 03, 2020 03:00
Molecules, Vol. 25, Pages 4532: New Mesoporous Silica-Supported Organocatalysts Based on (2S)-(1,2,4-Triazol-3-yl)-Proline: Efficient, Reusable, and Heterogeneous Catalysts for the Asymmetric Aldol Reaction Molecules doi: 10.3390/molecules25194532 Authors: Omar Sánchez-Antonio Kevin A. Romero-Sedglach Erika C. Vázquez-Orta Eusebio Juaristi Novel organocatalytic systems based on the recently developed (S)-proline derivative (2S)-[5-(benzylthio)-4-phenyl-(1,2,4-triazol)-3-yl]-pyrrolidine...
Sat Oct 03, 2020 03:00
Molecules, Vol. 25, Pages 4531: Synthesis of New Imidazopyridine Nucleoside Derivatives Designed as Maribavir Analogues Molecules doi: 10.3390/molecules25194531 Authors: Georgios Papadakis Maria Gerasi Robert Snoeck Panagiotis Marakos Graciela Andrei Nikolaos Lougiakis Nicole Pouli The strong inhibition of Human Cytomegalovirus (HCMV) replication by benzimidazole nucleosides, like Triciribine and Maribavir, has prompted us to expand the structure–activity...
Sat Oct 03, 2020 03:00
Molecules, Vol. 25, Pages 4530: Caryocar brasiliense Cambess. Pulp Oil Supplementation Reduces Total Cholesterol, LDL-c, and Non-HDL-c in Animals Molecules doi: 10.3390/molecules25194530 Authors: Gabriela Torres Silva Carolina Di Pietro Fernandes Priscila Aiko Hiane Karine de Cássia Freitas Priscila Silva Figueiredo Aline Carla Inada Wander Fernando Filiú Iriani Rodrigues Maldonade Ângela Alves Nunes Lincoln Carlos Silva de Oliveira Anderson Rodrigues Lima Caires...
Sat Oct 03, 2020 03:00
Molecules, Vol. 25, Pages 4529: Volatile Phenols—Important Contributors to the Aroma of Plant-Derived Foods Molecules doi: 10.3390/molecules25194529 Authors: Andreas Schieber Matthias Wüst Volatile phenols like phenylpropanoid and benzoid compounds originate from the aromatic amino acid phenylalanine, which is biosynthesized via the shikimate/arogenate pathway. These volatile compounds contribute to the aroma of a number of economically important plant-derived foods like herbs, spices...
Fri Oct 02, 2020 03:00
Molecules, Vol. 25, Pages 4528: Phytochemical Identification, Acute, and Sub-Acute Oral Toxicity Studies of the Foliar Extract of Withania frutescens Molecules doi: 10.3390/molecules25194528 Authors: Abdelfattah EL Moussaoui Mohammed Bourhia Fatima Zahra Jawhari Hamza Mechchate Meryem Slighoua Ahmed Bari Riaz Ullah Hafiz Majid Mahmood Syed Saeed Ali Samir Ibenmoussa Dalila Bousta Amina Bari Withania frutescens (W. frutescens) is a medicinal plant widely...
Fri Oct 02, 2020 03:00
Molecules, Vol. 25, Pages 4527: Ring-Closing Metathesis Approaches towards the Total Synthesis of Rhizoxins Molecules doi: 10.3390/molecules25194527 Authors: Marc Liniger Christian M. Neuhaus Karl-Heinz Altmann Efforts are described towards the total synthesis of the bacterial macrolide rhizoxin F, which is a potent tubulin assembly and cancer cell growth inhibitor. A significant amount of work was expanded on the construction of the rhizoxin core macrocycle by ring-closing olefin...
Fri Oct 02, 2020 03:00
Molecules, Vol. 25, Pages 4525: Actions of FTY720 (Fingolimod), a Sphingosine-1-Phosphate Receptor Modulator, on Delayed-Rectifier K+ Current and Intermediate-Conductance Ca2+-Activated K+ Channel in Jurkat T-Lymphocytes Molecules doi: 10.3390/molecules25194525 Authors: Wei-Ting Chang Ping-Yen Liu Sheng-Nan Wu FTY720 (fingolimod), a modulator of sphingosine-1-phosphate receptors, is known to produce the immunomodulatory actions and to be beneficial for treating the relapsing multiple...
Fri Oct 02, 2020 03:00
Molecules, Vol. 25, Pages 4526: Synthesis of “All-Cis” Trihydroxypiperidines from a Carbohydrate-Derived Ketone: Hints for the Design of New β-Gal and GCase Inhibitors Molecules doi: 10.3390/molecules25194526 Authors: Maria Giulia Davighi Francesca Clemente Camilla Matassini Amelia Morrone Andrea Goti Macarena Martínez-Bailén Francesca Cardona Pharmacological chaperones (PCs) are small compounds able to rescue the activity of mutated lysosomal enzymes when used at subinhibitory...
Fri Oct 02, 2020 03:00
Molecules, Vol. 25, Pages 4524: Diradicalar Character and Ring Stability of Mesoionic Heterocyclic Oxazoles and Thiazoles by Ab Initio Mono and Multi-Reference Methods Molecules doi: 10.3390/molecules25194524 Authors: Antonio João da Silva Filho Lucinêz da Cruz Dantas Otávio Luís de Santana Mesoionics are neutral compounds that cannot be represented by a fully covalent or purely ionic structure. Among the possible mesomeric structures of these compounds are the diradical electronic...
Fri Oct 02, 2020 03:00
Molecules, Vol. 25, Pages 4523: BODIPY- and Porphyrin-Based Sensors for Recognition of Amino Acids and Their Derivatives Molecules doi: 10.3390/molecules25194523 Authors: Marco Farinone Karolina Urbańska Miłosz Pawlicki Molecular recognition is a specific non-covalent and frequently reversible interaction between two or more systems based on synthetically predefined character of the receptor. This phenomenon has been extensively studied over past few decades, being of particular...
Fri Oct 02, 2020 03:00
Molecules, Vol. 25, Pages 4521: Green Synthesis of Zinc Oxide Nanoparticles from Pomegranate (Punica granatum) Extracts and Characterization of Their Antibacterial Activity Molecules doi: 10.3390/molecules25194521 Authors: Ugochi Lydia Ifeanyichukwu Omolola Esther Fayemi Collins Njie Ateba This study assessed the antimicrobial efficacy of synthesized zinc oxide nanoparticles produced using aqueous extracts of pomegranate leaves and flowers designated ZnO-NPs-PL, ZnO-NPs-PF. In...
Fri Oct 02, 2020 03:00
Molecules, Vol. 25, Pages 4522: Application of Sorbents for Oil Spill Cleanup Focusing on Natural-Based Modified Materials: A Review Molecules doi: 10.3390/molecules25194522 Authors: Miltiadis Zamparas Dimitrios Tzivras Vassilios Dracopoulos Theophilos Ioannides Conventional synthetic sorbents for oil spill removal are the most widely applied materials, although they are not the optimal choices from an economic and environmental point of view. The use of inexpensive, abundant,...
Fri Oct 02, 2020 03:00
Molecules, Vol. 25, Pages 4520: Extraction Kinetics of Phenolic Antioxidants from the Hydro Distillation Residues of Rosemary and Effect of Pretreatment and Extraction Parameters Molecules doi: 10.3390/molecules25194520 Authors: Irini Psarrou Antigoni Oreopoulou Dimitrios Tsimogiannis Vassiliki Oreopoulou Rosemary residue, remaining after the distillation of essential oil, is currently unexploited, while it is a source of phenolic antioxidant components. This raw material was...
Fri Oct 02, 2020 03:00
Molecules, Vol. 25, Pages 4518: GaPO4 Single Crystals: Growth Condition by Hydrothermal Refluxing Method Molecules doi: 10.3390/molecules25194518 Authors: Denis Balitsky Etienne Philippot Vladimir Balitsky Ludmila Balitskaya Tatiana Setkova Tatiana Bublikova Philippe Papet Bulk GaPO4 is an advanced piezoelectric material operating under high temperatures according to the α-β phase transition at 970 °C. This work presents the technological...
Fri Oct 02, 2020 03:00
Molecules, Vol. 25, Pages 4519: Effect of Ligilactobacillus salivarius and Other Natural Components against Anaerobic Periodontal Bacteria Molecules doi: 10.3390/molecules25194519 Authors: Marzena Kucia Ewa Wietrak Mateusz Szymczak Paweł Kowalczyk In this present study, the bacteriostatic effect of Salistat SGL03 and the Lactobacillus salivarius strain contained in it was investigated in adults in in vivo and in vitro tests on selected red complex bacteria living in the subgingival...
Fri Oct 02, 2020 03:00
Molecules, Vol. 25, Pages 4516: Profiling Anticancer and Antioxidant Activities of Phenolic Compounds Present in Black Walnuts (Juglans nigra) Using a High-Throughput Screening Approach Molecules doi: 10.3390/molecules25194516 Authors: Khanh-Van Ho Anuradha Roy Sarah Foote Phuc H. Vo Namrita Lall Chung-Ho Lin Our recent studies have demonstrated multiple health-promoting benefits from black walnut kernels. These biological functions of black walnuts are likely associated...
Fri Oct 02, 2020 03:00
Molecules, Vol. 25, Pages 4517: Immunomodulative Effects of Chamaecyparis obtusa Essential Oil in Mouse Model of Allergic Rhinitis Molecules doi: 10.3390/molecules25194517 Authors: Seung-Heon Shin Mi-Kyung Ye Dong-Won Lee Mi-Hyun Che The present study aims to investigate the immunomodulatory effects of essential oil from Chamaecyparis obtusa (EOCO) in an ovalbumin (OVA)-induced allergic rhinitis (AR) mouse model. BALB/c mice were intraperitoneally sensitized and stimulated with...
Fri Oct 02, 2020 03:00
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