Microorganisms, Vol. 8, Pages 1560: The Neutrophil-to-Monocyte Ratio and Lymphocyte-to-Neutrophil Ratio at Admission Predict In-Hospital Mortality in Mexican Patients with Severe SARS-CoV-2 Infection (Covid-19) Microorganisms doi: 10.3390/microorganisms8101560 Authors: Salma A. Rizo-Téllez Lucia A. Méndez-García Cruz Flores-Rebollo Fernando Alba-Flores Raúl Alcántara-Suárez Aarón N. Manjarrez-Reyna Neyla Baltazar-López Verónica A. Hernández-Guzmán José I. León-Pedroza...
Sat Oct 10, 2020 03:00
Microorganisms, Vol. 8, Pages 1561: Population Genomic Analysis of Mycoplasma bovis Elucidates Geographical Variations and Genes associated with Host-Types Microorganisms doi: 10.3390/microorganisms8101561 Authors: Kumar Register Christopher-Hennings Moroni Gioia Garcia-Fernandez Nelson Jelinski Lysnyansky Bayles Alt Scaria : Among more than twenty species belonging to the class Mollecutes, Mycoplasma bovis is the most common cause of bovine...
Sat Oct 10, 2020 03:00
Microorganisms, Vol. 8, Pages 1558: The hns Gene of Escherichia coli Is Transcriptionally Down-Regulated by (p)ppGpp Microorganisms doi: 10.3390/microorganisms8101558 Authors: Brandi Giangrossi Fabbretti Falconi Second messenger nucleotides, such as guanosine penta- or tetra-phosphate, commonly referred to as (p)ppGpp, are powerful signaling molecules, used by all bacteria to fine-tune cellular metabolism in response to nutrient availability. Indeed, under nutritional starvation,...
Sat Oct 10, 2020 03:00
Microorganisms, Vol. 8, Pages 1557: Sphingopyxis sp. Strain OPL5, an Isoprene-Degrading Bacterium from the Sphingomonadaceae Family Isolated from Oil Palm Leaves Microorganisms doi: 10.3390/microorganisms8101557 Authors: Larke-Mejía Carrión Crombie McGenity Murrell The volatile secondary metabolite, isoprene, is released by trees to the atmosphere in enormous quantities, where it has important effects on air quality and climate. Oil palm trees, one of the highest isoprene...
Sat Oct 10, 2020 03:00
Microorganisms, Vol. 8, Pages 1559: Optimized Production of a Redox Metabolite (pyocyanin) by Pseudomonas aeruginosa NEJ01R Using a Maize By-Product Microorganisms doi: 10.3390/microorganisms8101559 Authors: Francisco Javier Bacame-Valenzuela Jesús Alberto Pérez-Garcia Mayra Leticia Figueroa-Magallón Fabricio Espejel-Ayala Luis Antonio Ortiz-Frade Yolanda Reyes-Vidal Pseudomonas aeruginosa metabolizes pyocyanin, a redox molecule related to diverse biological activities....
Sat Oct 10, 2020 03:00
Microorganisms, Vol. 8, Pages 1556: Differential Pathogenic Gene Expression of E. histolytica in Patients with Different Clinical Forms of Amoebiasis Microorganisms doi: 10.3390/microorganisms8101556 Authors: Enrique González-Rivas Miriam Nieves-Ramírez Ulises Magaña Patricia Morán Liliana Rojas-Velázquez Eric Hernández Angélica Serrano-Vázquez Oswaldo Partida Horacio Pérez-Juárez Cecilia Ximénez The etiological agent of human amoebiasis is the protozoan parasite...
Fri Oct 09, 2020 03:00
Microorganisms, Vol. 8, Pages 1555: Clinical Relevance of Antibiotic Susceptibility Profiles for Screening Gram-negative Microorganisms Resistant to Beta-Lactam Antibiotics Microorganisms doi: 10.3390/microorganisms8101555 Authors: Francisco Montiel-Riquelme Elisabeth Calatrava-Hernández Miguel Gutiérrez-Soto Manuela Expósito-Ruiz José María Navarro-Marí José Gutiérrez-Fernández The increasing resistance to antibiotics is compromising the empirical treatment of infections...
Fri Oct 09, 2020 03:00
Microorganisms, Vol. 8, Pages 1554: HybridMine: A Pipeline for Allele Inheritance and Gene Copy Number Prediction in Hybrid Genomes and Its Application to Industrial Yeasts Microorganisms doi: 10.3390/microorganisms8101554 Authors: Soukaina Timouma Jean-Marc Schwartz Daniela Delneri Genome-scale computational approaches are opening opportunities to model and predict favorable combination of traits for strain development. However, mining the genome of complex hybrids is not currently...
Fri Oct 09, 2020 03:00
Microorganisms, Vol. 8, Pages 1553: Seroprevalence and Associated Risk Factors of Bovine Brucellosis at the Wildlife-Livestock-Human Interface in Rwanda Microorganisms doi: 10.3390/microorganisms8101553 Authors: Jean Bosco Ntivuguruzwa Francis Babaman Kolo Richard Simba Gashururu Lydia Umurerwa Charles Byaruhanga Henriette van Heerden Bovine brucellosis is endemic in Rwanda; however, little information is available on seroprevalence and risk factors. Therefore, a cross-sectional...
Fri Oct 09, 2020 03:00
Molecules, Vol. 25, Pages 4629: A Template-Based Approach for Guiding and Refining the Development of Cinnamon-Based Phenylpropanoids as Drugs Molecules doi: 10.3390/molecules25204629 Authors: Ngoc Uy Nguyen Brendan David Stamper Background: Structure-activity relationships describe the relationship between chemical structure and biologic activity and are capable of informing deliberate structural modifications to a molecule in order enhance drug properties. Methods: Here, we present...
Sun Oct 11, 2020 03:00
Molecules, Vol. 25, Pages 4628: Response Surface Optimization of Oil Removal Using Synthesized Polypyrrole-Silica Polymer Composite Molecules doi: 10.3390/molecules25204628 Authors: Oisaemi Uduagele Izevbekhai Wilson Mugera Gitari Nikita Tawanda Tavengwa Wasiu Babatunde Ayinde Rabelani Mudzielwana The severity of oil pollution, brought about by improper management, increases daily with an increase in the exploration and usage of oil, especially with an increase in industrialization....
Sun Oct 11, 2020 03:00
Molecules, Vol. 25, Pages 4627: Molecular Sensing with Host Systems for Hyperpolarized 129Xe Molecules doi: 10.3390/molecules25204627 Authors: Jayapaul Schröder Hyperpolarized noble gases have been used early on in applications for sensitivity enhanced NMR. 129Xe has been explored for various applications because it can be used beyond the gas-driven examination of void spaces. Its solubility in aqueous solutions and its affinity for hydrophobic binding pockets allows “functionalization”...
Sun Oct 11, 2020 03:00
Molecules, Vol. 25, Pages 4626: Preventative and Therapeutic Potential of Flavonoids in Peptic Ulcers Molecules doi: 10.3390/molecules25204626 Authors: Wenji Zhang Yingyi Lian Qiuhua Li Lingli Sun Ruohong Chen Xingfei Lai Zhaoxiang Lai Erdong Yuan Shili Sun Peptic ulcer disease is a common gastrointestinal tract disorder that affects up to 20% of the population of the world. Treatment of peptic ulcer remains challenging due to the limited effectiveness and severe...
Sun Oct 11, 2020 03:00
Molecules, Vol. 25, Pages 4625: Bioanalytical Method Using Ultra-High-Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry (UHPL-CHRMS) for the Detection of Metformin in Human Plasma Molecules doi: 10.3390/molecules25204625 Authors: Ye-Ji Kang Hyeon-Cheol Jeong Tae-Eun Kim Kwang-Hee Shin Metformin is the first-line medicine for the treatment of type 2 diabetes. Drug interactions between metformin and other drugs, food, or beverages cannot only cause...
Sun Oct 11, 2020 03:00
Molecules, Vol. 25, Pages 4624: Drug-Eluting Stents and Balloons—Materials, Structure Designs, and Coating Techniques: A Review Molecules doi: 10.3390/molecules25204624 Authors: I. Rykowska I. Nowak R. Nowak Controlled drug delivery is a matter of interest to numerous scientists from various domains, as well as an essential issue for society as a whole. In the treatment of many diseases, it is crucial to control the dosing of a drug for a long time and thus maintain its optimal...
Sun Oct 11, 2020 03:00
Molecules, Vol. 25, Pages 4623: In Silico Molecular Study of Tryptophan Bitterness Molecules doi: 10.3390/molecules25204623 Authors: Antonella Di Pizio Alessandro Nicoli Tryptophan is an essential amino acid, required for the production of serotonin. It is the most bitter amino acid and its bitterness was found to be mediated by the bitter taste receptor TAS2R4. Di-tryptophan has a different selectivity profile and was found to activate three bitter taste receptors, whereas tri-tryptophan...
Sun Oct 11, 2020 03:00
Molecules, Vol. 25, Pages 4622: Ultrastructure of Cells and Microanalysis in Malus domestica Borkh. ‘Szampion’ Fruit in Relation to Varied Calcium Foliar Feeding Molecules doi: 10.3390/molecules25204622 Authors: Piotr Kowalik Tomasz Lipa Zenia Michałojć Mirosława Chwil Calcium is one of the most poorly reutilized nutrients. Its deficiencies cause various physiological disturbances and, consequently, reduce the quantity and quality of yields. Reduced content of Ca2+ ions in cells...
Sun Oct 11, 2020 03:00
Molecules, Vol. 25, Pages 4618: N-Alkylated Iminosugar Based Ligands: Synthesis and Inhibition of Human Lysosomal β-Glucocerebrosidase Molecules doi: 10.3390/molecules25204618 Authors: Andreas Wolfsgruber Martin Thonhofer Patrick Weber Seyed A. Nasseri Roland Fischer Michael Schalli Arnold E. Stütz Stephen G. Withers Tanja M. Wrodnigg The scope of a series of N-alkylated iminosugar based inhibitors in the d-gluco as well as d-xylo configuration towards their interaction...
Sun Oct 11, 2020 03:00
Molecules, Vol. 25, Pages 4617: Photoprotective Role of Neoxanthin in Plants and Algae Molecules doi: 10.3390/molecules25204617 Authors: Chiara Giossi Paulo Cartaxana Sónia Cruz Light is a paramount parameter driving photosynthesis. However, excessive irradiance leads to the formation of reactive oxygen species that cause cell damage and hamper the growth of photosynthetic organisms. Xanthophylls are key pigments involved in the photoprotective response of plants and algae to excessive...
Sun Oct 11, 2020 03:00
Molecules, Vol. 25, Pages 4620: Biomedical Science to Tackle the COVID-19 Pandemic: Current Status and Future Perspectives Molecules doi: 10.3390/molecules25204620 Authors: Zamora-Ledezma C. Medina Sinche Vispo Dahoumane Alexis The coronavirus infectious disease (COVID-19) pandemic emerged at the end of 2019, and was caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which has resulted in an unprecedented health and economic crisis worldwide....
Sun Oct 11, 2020 03:00
Molecules, Vol. 25, Pages 4619: Imipramine Inhibits Migration and Invasion in Metastatic Castration-Resistant Prostate Cancer PC-3 Cells via AKT-Mediated NF-κB Signaling Pathway Molecules doi: 10.3390/molecules25204619 Authors: Lim Park Kim Kim Imipramine (IMI) is a tricyclic synthetic antidepressant that is used to treat chronic psychiatric disorders, including depression and neuropathic pain. IMI also has inhibitory effects against various cancer types, including prostate...
Sun Oct 11, 2020 03:00
Molecules, Vol. 25, Pages 4621: Antibody-Targeted Imaging of Gastric Cancer Molecules doi: 10.3390/molecules25204621 Authors: Komal Mandleywala Shayla Shmuel Patricia M. R. Pereira Jason S. Lewis The specificity of antibodies for antigens overexpressed or uniquely expressed in tumor cells makes them ideal candidates in the development of bioconjugates for tumor imaging. Molecular imaging can aid clinicians in the diagnosis of gastric tumors and in selecting patients for therapies...
Sun Oct 11, 2020 03:00
Molecules, Vol. 25, Pages 4616: Silver Fir (Abies alba L.) Polyphenolic Extract Shows Beneficial Influence on Chondrogenesis In Vitro under Normal and Inflammatory Conditions Molecules doi: 10.3390/molecules25204616 Authors: Mateja Sirše Samo K. Fokter Borut Štrukelj Janja Zupan Several plant polyphenols have been shown to reduce osteoarthritis symptoms due to their antioxidant, anti-inflammatory and immunomodulatory properties. We investigated the effects of two different polyphenolic...
Sun Oct 11, 2020 03:00
Molecules, Vol. 25, Pages 4615: Nutritional Enhancement of Farmed Salmon Meat via Non-GMO Nannochloropsis Gaditana: Eicosapentaenoic Acid (EPA, 20:5 n-3), Docosapentaenoic Acid (DPA, 22:5 n-3) and Vitamin D3 for Human Health Molecules doi: 10.3390/molecules25204615 Authors: Ivonne Lozano-Muñoz Susana Muñoz Nelson F. Díaz Alberto Medina Jazmín Bazaes Carlos Riquelme Omega-3 long-chain polyunsaturated fatty acids (n-3 LC PUFAs) and vitamin D3 are essential components of...
Sat Oct 10, 2020 03:00
Molecules, Vol. 25, Pages 4614: Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin Transporter, Dopamine D2 Receptor, and Mao-A Enzyme: In the Pursuit for Potential Multitarget Directed Ligands Molecules doi: 10.3390/molecules25204614 Authors: Christopher Cerda-Cavieres Gabriel Quiroz Patricio Iturriaga-Vásquez Julio Rodríguez-Lavado Jazmín Alarcón-Espósito Claudio Saitz Carlos D. Pessoa-Mahana Hery Chung Ramiro Araya-Maturana...
Sat Oct 10, 2020 03:00
Molecules, Vol. 25, Pages 4612: The Chemical Composition of Brazilian Green Propolis and Its Protective Effects on Mouse Aortic Endothelial Cells against Inflammatory Injury Molecules doi: 10.3390/molecules25204612 Authors: Xiaolan Xu Bo Yang Danfeng Wang Yuxuan Zhu Xiaoqing Miao Wenchao Yang Propolis has a very complex composition, with antibacterial, anti-inflammatory and other properties. To determine the composition of ethanol extracts of Brazilian green propolis (EEP-B)...
Sat Oct 10, 2020 03:00
Molecules, Vol. 25, Pages 4613: Nanoformulations to Enhance the Bioavailability and Physiological Functions of Polyphenols Molecules doi: 10.3390/molecules25204613 Authors: Bingyan Yang Yixin Dong Fei Wang Yu Zhang Polyphenols are micronutrients that are widely present in human daily diets. Numerous studies have demonstrated their potential as antioxidants and anti-inflammatory agents, and for cancer prevention, heart protection and the treatment of neurodegenerative diseases....
Sat Oct 10, 2020 03:00
Molecules, Vol. 25, Pages 4611: Validated Reversed-Phase Liquid Chromatographic Method with Gradient Elution for Simultaneous Determination of the Antiviral Agents: Sofosbuvir, Ledipasvir, Daclatasvir, and Simeprevir in Their Dosage Forms Molecules doi: 10.3390/molecules25204611 Authors: Essam Ezzeldin Nisreen F. Abo-Talib Marwa H. Tammam Yousif A. Asiri Abd El-Galil E. Amr Abdulrahman A. Almehizia A simple, rapid, sensitive, and precise reversed-phase liquid chromatographic...
Sat Oct 10, 2020 03:00
Molecules, Vol. 25, Pages 4607: Effect of Different Enological Tannins on Oxygen Consumption, Phenolic Compounds, Color and Astringency Evolution of Aglianico Wine Molecules doi: 10.3390/molecules25204607 Authors: Picariello Rinaldi Forino Errichiello Moio Gambuti Background: In the wine industry, in addition to condensed tannins of grape origin, other commercial tannins are commonly used. However, the influence of oxygen uptake related to different tannin additions...
Sat Oct 10, 2020 03:00
Molecules, Vol. 25, Pages 4609: Improvement of Chemical Composition of Tisochrysis lutea Grown Mixotrophically under Nitrogen Depletion towards Biodiesel Production Molecules doi: 10.3390/molecules25204609 Authors: Almutairi : In the present study, the marine microalga Tisochrysis lutea was cultivated mixotrophically in F2 growth medium with sodium acetate as exogenous carbon source. The medium was composed of different concentrations of nitrogen to determine the impact of nitrogen...
Sat Oct 10, 2020 03:00
Molecules, Vol. 25, Pages 4608: Extract Derived from Cedrus atlantica Acts as an Antitumor Agent on Hepatocellular Carcinoma Growth In Vitro and In Vivo Molecules doi: 10.3390/molecules25204608 Authors: Huang Chang Lee Sheu Li Weng Hsiao Tsai Cedrus atlantica is widely used in herbal medicine. However, the anti-cancer activity of C. atlantica extract (CAt extract) has not been clarified in hepatocellular carcinoma. In the study, we elucidated the anti-hepatoma...
Sat Oct 10, 2020 03:00
Molecules, Vol. 25, Pages 4606: Significance of Targeting VEGFR-2 and Cyclin D1 in Luminal-A Breast Cancer Molecules doi: 10.3390/molecules25204606 Authors: Abdalla Qattan Malki Shahid Hossain Ahmed The hormonal luminal-A is the most pre-dominant sub type of breast cancer (BC), and it is associated with a high level of cyclin D1 in Saudi patients. Tamoxifen is the golden therapy for hormonal BC, but resistance of cancer cells to tamoxifen contributes to the recurrence...
Sat Oct 10, 2020 03:00
Molecules, Vol. 25, Pages 4610: An EGF- and Curcumin-Co-Encapsulated Nanostructured Lipid Carrier Accelerates Chronic-Wound Healing in Diabetic Rats Molecules doi: 10.3390/molecules25204610 Authors: Lee Jeong Na Kim Lee Cho Nanostructured lipid carriers (NLC) are capable of encapsulating hydrophilic and lipophilic drugs. The present study developed an NLC containing epidermal growth factor (EGF) and curcumin (EGF–Cur-NLC). EGF–Cur-NLC was prepared...
Sat Oct 10, 2020 03:00
Molecules, Vol. 25, Pages 4605: Morphology, Surface Structure and Water Adsorption Properties of TiO2 Nanoparticles: A Comparison of Different Commercial Samples Molecules doi: 10.3390/molecules25204605 Authors: Lorenzo Mino Chiara Negri Rosangela Santalucia Giuseppina Cerrato Giuseppe Spoto Gianmario Martra Water is a molecule always present in the reaction environment in photocatalytic and biomedical applications of TiO2 and a better understanding of its interaction...
Sat Oct 10, 2020 03:00
Molecules, Vol. 25, Pages 4604: Protease Inhibitory Effect of Natural Polyphenolic Compounds on SARS-CoV-2: An In Silico Study Molecules doi: 10.3390/molecules25204604 Authors: Rajveer Singh Anupam Gautam Shivani Chandel Arijit Ghosh Dhritiman Dey Syamal Roy Velayutham Ravichandiran Dipanjan Ghosh The current pandemic, caused by SARS-CoV-2 virus, is a severe challenge for human health and the world economy. There is an urgent need for development of drugs that can...
Sat Oct 10, 2020 03:00
Molecules, Vol. 25, Pages 4603: Ethylchloroformate Derivatization for GC–MS Analysis of Resveratrol Isomers in Red Wine Molecules doi: 10.3390/molecules25204603 Authors: Elisa Di Fabio Alessio Incocciati Federica Palombarini Alberto Boffi Alessandra Bonamore Alberto Macone Resveratrol (3,5,4′-trihydroxystilbene) is a natural compound that can be found in high concentrations in red wine and in many typical foods found in human diet. Over the past decades, resveratrol...
Fri Oct 09, 2020 03:00
Molecules, Vol. 25, Pages 4601: Electrochemotherapy Using Doxorubicin and Nanosecond Electric Field Pulses: A Pilot In Vivo Study Molecules doi: 10.3390/molecules25204601 Authors: Novickij Malyško Želvys Balevičiūtė Zinkevičienė Novickij Girkontaitė Pulsed electric field (PEF) is frequently used for intertumoral drug delivery resulting in a well-known anticancer treatment—electrochemotherapy. However, electrochemotherapy is associated with microsecond...
Fri Oct 09, 2020 03:00
Molecules, Vol. 25, Pages 4600: Mass Spectrometry Imaging of Flavonols and Ellagic Acid Glycosides in Ripe Strawberry Fruit Molecules doi: 10.3390/molecules25204600 Authors: Hirofumi Enomoto Flavonols and ellagic acid glycosides are major phenolic compounds in strawberry fruit. They have antioxidant activity, show protective functions against abiotic and biotic stress, and provide health benefits. However, their spatial distribution in ripe fruit has not been understood. Therefore, matrix-assisted...
Fri Oct 09, 2020 03:00
Molecules, Vol. 25, Pages 4602: Nanohydroxyapatite-Mediated Imatinib Delivery for Specific Anticancer Applications Molecules doi: 10.3390/molecules25204602 Authors: Paulina Sobierajska Anna Serwotka-Suszczak Damian Szymanski Krzysztof Marycz Rafal J. Wiglusz In the present study, a nanoapatite-mediated delivery system for imatinib has been proposed. Nanohydroxyapatite (nHAp) was obtained by co-precipitation method, and its physicochemical properties in combination with imatinib...
Fri Oct 09, 2020 03:00
Molecules, Vol. 25, Pages 4599: Full-Spectrum Analysis of Bioactive Compounds in Rosemary (Rosmarinus officinalis L.) as Influenced by Different Extraction Methods Molecules doi: 10.3390/molecules25204599 Authors: Sharma Velamuri Fagan Schaefer Rosmarinus officinalis is a potent antioxidant herb rich in polyphenols. Ultra-high-performance liquid chromatography, coupled with electrospray ionization and quadrupole-time of flight mass spectrometry (UHPLC-ESI-QTOF-MS), enables...
Fri Oct 09, 2020 03:00
Molecules, Vol. 25, Pages 4597: NMR as a “Gold Standard” Method in Drug Design and Discovery Molecules doi: 10.3390/molecules25204597 Authors: Emwas Szczepski Poulson Chandra McKay Dhahri Alahmari Jaremko Lachowicz Jaremko Studying disease models at the molecular level is vital for drug development in order to improve treatment and prevent a wide range of human pathologies. Microbial infections are still a major challenge because pathogens rapidly...
Fri Oct 09, 2020 03:00
Molecules, Vol. 25, Pages 4596: Investigating the Modes of Action of the Antimicrobial Chalcones BC1 and T9A Molecules doi: 10.3390/molecules25204596 Authors: Luana G. Morão André S. G. Lorenzoni Parichita Chakraborty Gabriela M. Ayusso Lucia B. Cavalca Mariana B. Santos Beatriz C. Marques Guilherme Dilarri Caio Zamuner Luis O. Regasini Henrique Ferreira Dirk-Jan Scheffers Xanthomonas citri subsp. citri (X. citri) is an important phytopathogen and causes...
Fri Oct 09, 2020 03:00
Molecules, Vol. 25, Pages 4598: Conversion of CO2 into Chloropropene Carbonate Catalyzed by Iron (II) Phthalocyanine Hypercrosslinked Porous Organic Polymer Molecules doi: 10.3390/molecules25204598 Authors: Maya Valverde-González Iglesias Commercial iron (II) phthalocyanine (FePc) was knitted with biphenyl using a Friedel–Crafts reaction to yield a micro-meso porous organic polymer (FePc-POP) with a specific surface area of 427 m2/g and 5.42% of iron loading. This...
Fri Oct 09, 2020 03:00
Molecules, Vol. 25, Pages 4595: Bis-Phenoxo-CuII2 Complexes: Formal Aromatic Hydroxylation via Aryl-CuIII Intermediate Species Molecules doi: 10.3390/molecules25204595 Authors: Xavi Ribas Raül Xifra Xavier Fontrodona Ullmann-type copper-mediated arylC-O bond formation has attracted the attention of the catalysis and organometallic communities, although the mechanism of these copper-catalyzed coupling reactions remains a subject of debate. We have designed well-defined triazamacrocyclic-based...
Fri Oct 09, 2020 03:00
Molecules, Vol. 25, Pages 4594: Loseolamycins: A Group of New Bioactive Alkylresorcinols Produced after Heterologous Expression of a Type III PKS from Micromonospora endolithica Molecules doi: 10.3390/molecules25204594 Authors: Constanze Lasch Nils Gummerlich Maksym Myronovskyi Anja Palusczak Josef Zapp Andriy Luzhetskyy Natural products are a valuable source of biologically active compounds with potential applications in medicine and agriculture. Unprecedented scaffold...
Fri Oct 09, 2020 03:00
Molecules, Vol. 25, Pages 4593: Enzyme Stability in Nanoparticle Preparations Part 1: Bovine Serum Albumin Improves Enzyme Function Molecules doi: 10.3390/molecules25204593 Authors: Jason Thomas Duskey Federica da Ros Ilaria Ottonelli Barbara Zambelli Maria Angela Vandelli Giovanni Tosi Barbara Ruozi Enzymes have gained attention for their role in numerous disease states, calling for research for their efficient delivery. Loading enzymes into polymeric nanoparticles...
Fri Oct 09, 2020 03:00
Molecules, Vol. 25, Pages 4592: Water Extract of Lotus Leaf Alleviates Dexamethasone-Induced Muscle Atrophy via Regulating Protein Metabolism-Related Pathways in Mice Molecules doi: 10.3390/molecules25204592 Authors: Sang Hee Park Jieun Oh Minkyeong Jo Jin Kyeong Kim Dong Seon Kim Han Gyung Kim Keejung Yoon Yoonyong Yang Jeong-ho Geum Jung-Eun Kim Su-Young Choi Ji Hye Kim Jae Youl Cho Muscle atrophy is an abnormal condition characterized by loss of...
Fri Oct 09, 2020 03:00
Nanomaterials, Vol. 10, Pages 2004: Recent Advances of Graphene-Derived Nanocomposites in Water-Based Drilling Fluids Nanomaterials doi: 10.3390/nano10102004 Authors: Rabia Ikram Badrul Mohamed Jan Jana Vejpravova M. Iqbal Choudhary Zaira Zaman Chowdhury Nanocomposite materials have distinctive potential for various types of captivating usage in drilling fluids as a well-designed solution for the petroleum industry. Owing to the improvement of drilling fluids, it is of great...
Sun Oct 11, 2020 03:00
Nanomaterials, Vol. 10, Pages 2003: Maximizing the Field Emission Performance of Graphene Arrays Nanomaterials doi: 10.3390/nano10102003 Authors: Kaiqiang Yang Jianlong Liu Ruirui Jiang Yubing Gong Baoqing Zeng Jianjun Yang Feng Chi Liming Liu To design efficient and powerful field emission cathodes, the screening effect is of great importance and should be traded off between screening and emitter number. It has long been found that to achieve maximum emission efficiency...
Sun Oct 11, 2020 03:00
Nanomaterials, Vol. 10, Pages 2002: Rational Regulation of Surface Free Radicals on TiO2 Nanotube Arrays via Ag2O–AgBiO3 towards Enhanced Selective Photoelectrochemical Detection Nanomaterials doi: 10.3390/nano10102002 Authors: Yajun Pang Hao Chen Jin Yang Bo Wang Zhenyu Yang Jun Lv Zhenghui Pan Guangqing Xu Zhehong Shen Yucheng Wu Due to integrated advances in photoelectrochemical (PEC) functionalities for environment detection applications, one-dimensional...
Sun Oct 11, 2020 03:00
Nanomaterials, Vol. 10, Pages 2001: Novel Crown Cement Containing Antibacterial Monomer and Calcium Phosphate Nanoparticles Nanomaterials doi: 10.3390/nano10102001 Authors: Rashed AlSahafi Abdulrahman A. Balhaddad Heba Mitwalli Maria Salem Ibrahim Mary Anne S. Melo Thomas W. Oates Hockin H.K. Xu Michael D. Weir Oral biofilm accumulation at the tooth–restoration interface often leads to recurrent dental caries and restoration failure. The objectives of this...
Sun Oct 11, 2020 03:00
Nanomaterials, Vol. 10, Pages 1999: Structures and Properties of the Self-Assembling Diphenylalanine Peptide Nanotubes Containing Water Molecules: Modeling and Data Analysis Nanomaterials doi: 10.3390/nano10101999 Authors: Vladimir Bystrov Jose Coutinho Pavel Zelenovskiy Alla Nuraeva Svitlana Kopyl Olga Zhulyabina Vsevolod Tverdislov The structures and properties of the diphenylalanine (FF) peptide nanotubes (PNTs), both L-chiral and D-chiral (L-FF and D-FF) and empty...
Sat Oct 10, 2020 03:00
Nanomaterials, Vol. 10, Pages 1997: The Influence of Ozonated Olive Oil-Loaded and Copper-Doped Nanohydroxyapatites on Planktonic Forms of Microorganisms Nanomaterials doi: 10.3390/nano10101997 Authors: Wojciech Zakrzewski Maciej Dobrzynski Joanna Nowicka Magdalena Pajaczkowska Maria Szymonowicz Sara Targonska Paulina Sobierajska Katarzyna Wiglusz Wojciech Dobrzynski Adam Lubojanski Sebastian Fedorowicz Zbigniew Rybak Rafal J. Wiglusz The research...
Sat Oct 10, 2020 03:00
Nanomaterials, Vol. 10, Pages 1998: Formation of Periodic Nanoridge Patterns by Ultrashort Single Pulse UV Laser Irradiation of Gold Nanomaterials doi: 10.3390/nano10101998 Authors: Blumenstein Garcia Rethfeld Simon Ihlemann Ivanov Abstract: A direct comparison of simulation and experimental results of UV laser-induced surface nanostructuring of gold is presented. Theoretical simulations and experiments are performed on an identical spatial scale. The experimental...
Sat Oct 10, 2020 03:00
Nanomaterials, Vol. 10, Pages 2000: Polydopamine-Modified Metal–Organic Frameworks, NH2-Fe-MIL-101, as pH-Sensitive Nanocarriers for Controlled Pesticide Release Nanomaterials doi: 10.3390/nano10102000 Authors: Shan Xu Zhang Chen Bilal Niu Cao Huang : Recently, metal–organic frameworks (MOFs) have become a dazzling star among porous materials used in many fields. Considering their intriguing features, MOFs have great prospects for application in...
Sat Oct 10, 2020 03:00
Nanomaterials, Vol. 10, Pages 1995: Onion-Structured Si Anode Constructed with Coating by Li4Ti5O12 and Cyclized-Polyacrylonitrile for Lithium-Ion Batteries Nanomaterials doi: 10.3390/nano10101995 Authors: Arailym Nurpeissova Aliya Mukanova Gulnur Kalimuldina Nurzhan Umirov Sung-Soo Kim Zhumabay Bakenov Low dimensional Si-based materials are very promising anode candidates for the next-generation lithium-ion batteries. However, to satisfy the ever-increasing demand in...
Sat Oct 10, 2020 03:00
Nanomaterials, Vol. 10, Pages 1996: Interface-Induced Near-Infrared Response of Gold-Silica Hybrid Nanoparticles Antennas Nanomaterials doi: 10.3390/nano10101996 Authors: Atta Ur Rahman Junping Geng Sami Ur Rehman Muhammad Javid Iqbal Ronghong Jin We proposed an IR absorber hybrid nanoantenna comprise of two overlapping gold nanoparticles residing over larger a silica nanoparticle. A wet chemical route was employed to prepare the hybrid structure of nanoantenna. High-resolution...
Sat Oct 10, 2020 03:00
Nanomaterials, Vol. 10, Pages 1994: Preparations of NiFe2O4 Yolk-Shell@C Nanospheres and Their Performances as Anode Materials for Lithium-Ion Batteries Nanomaterials doi: 10.3390/nano10101994 Authors: Tianli Liu Qinghua Gong Pei Cao Xuefeng Sun Jing Ren Shaonan Gu Guowei Zhou At present, lithium-ion batteries (LIBs) have received widespread attention as substantial energy storage devices; thus, their electrochemical performances must be continuously researched and...
Fri Oct 09, 2020 03:00
Nanomaterials, Vol. 10, Pages 1993: Sensitive SQUID Bio-Magnetometry for Determination and Differentiation of Biogenic Iron and Iron Oxide Nanoparticles in the Biological Samples Nanomaterials doi: 10.3390/nano10101993 Authors: Martin Škrátek Andrej Dvurečenskij Michal Kluknavský Andrej Barta Peter Bališ Andrea Mičurová Alexander Cigáň Anita Eckstein-Andicsová Ján Maňka Iveta Bernátová This study aimed to develop the method for determination of the ultra-small...
Fri Oct 09, 2020 03:00
Nanomaterials, Vol. 10, Pages 1989: Design and Synthesis of Novel 2D Porous Zinc Oxide-Nickel Oxide Composite Nanosheets for Detecting Ethanol Vapor Nanomaterials doi: 10.3390/nano10101989 Authors: Yuan-Chang Liang Yen-Cheng Chang Wei-Cheng Zhao The porous zinc oxide-nickel oxide (ZnO-NiO) composite nanosheets were synthesized via sputtering deposition of NiO thin film on the porous ZnO nanosheet templates. Various NiO film coverage sizes on porous ZnO nanosheet templates were...
Fri Oct 09, 2020 03:00
Nanomaterials, Vol. 10, Pages 1992: Temperature Sensing in the Short-Wave Infrared Spectral Region Using Core-Shell NaGdF4:Yb3+, Ho3+, Er3+@NaYF4 Nanothermometers Nanomaterials doi: 10.3390/nano10101992 Authors: Daria Pominova Vera Proydakova Igor Romanishkin Anastasia Ryabova Sergei Kuznetsov Oleg Uvarov Pavel Fedorov Victor Loschenov The short-wave infrared region (SWIR) is promising for deep-tissue visualization and temperature sensing due to higher penetration...
Fri Oct 09, 2020 03:00
Nanomaterials, Vol. 10, Pages 1990: Surface Modification and Enhancement of Ferromagnetism in BiFeO3 Nanofilms Deposited on HOPG Nanomaterials doi: 10.3390/nano10101990 Authors: Shikhgasan Ramazanov Dinara Sobola Farid Orudzhev Alexandr Knápek Josef Polčák Potoček Pavel Kaspar Rashid Dallaev BiFeO3 (BFO) films on highly oriented pyrolytic graphite (HOPG) substrate were obtained by the atomic layer deposition (ALD) method. The oxidation of HOPG leads to the formation...
Fri Oct 09, 2020 03:00
Nanomaterials, Vol. 10, Pages 1991: Enhancing Methane Aromatization Performance by Reducing the Particle Size of Molybdenum Oxide Nanomaterials doi: 10.3390/nano10101991 Authors: Jing Hu Jinghai Liu Jinglin Liu Yangyang Li Peihe Li Yin Wang Jingqi Guan Qiubin Kan Efficient use of natural gas to produce aromatics is an attractive subject; the process requires catalysts that possess high-performance active sites to activate stable C–H bonds. Here, we report...
Fri Oct 09, 2020 03:00
Nanomaterials, Vol. 10, Pages 1988: Ni-Cu Nanoparticles and Their Feasibility for Magnetic Hyperthermia Nanomaterials doi: 10.3390/nano10101988 Authors: Bianca P. Meneses-Brassea Edgar A. Borrego Dawn S. Blazer Mohamed F. Sanad Shirin Pourmiri Denisse A. Gutierrez Armando Varela-Ramirez George C. Hadjipanayis Ahmed A. El-Gendy Ni-Cu nanoparticles have been synthesized by reducing Ni and Cu from metal precursors using a sol–gel route followed by annealing...
Fri Oct 09, 2020 03:00
Nutrients, Vol. 12, Pages 3096: Protective Effect of Vitis labrusca Leaves Extract on Cardiovascular Dysfunction through HMGB1-TLR4-NFκB Signaling in Spontaneously Hypertensive Rats Nutrients doi: 10.3390/nu12103096 Authors: Hye Yoom Kim Mi Hyeon Hong Jung Joo Yoon Dae Sung Kim Se Won Na Youn Jae Jang Yun Jung Lee Dae Gill Kang Ho Sub Lee The Vitis labrusca is a grapevine that has antioxidant, neuroprotective, hepatoprotective, and anticarcinogenic activity. However,...
Sun Oct 11, 2020 03:00
Nutrients, Vol. 12, Pages 3091: The Association between Nutritional Status and In-Hospital Mortality among Patients with Acute Coronary Syndrome—A Result of the Retrospective Nutritional Status Heart Study (NSHS) Nutrients doi: 10.3390/nu12103091 Authors: Michał Czapla Piotr Karniej Raúl Juárez-Vela Katarzyna Łokieć Background: Nutritional status is related to the prognosis and the length of hospitalization of individuals with myocardial infarction. This study aimed to assess...
Sun Oct 11, 2020 03:00
Nutrients, Vol. 12, Pages 3094: Maternal Arsenic Exposure and Gestational Diabetes: A Systematic Review and Meta-Analysis Nutrients doi: 10.3390/nu12103094 Authors: Noemi Salmeri Roberta Villanacci Jessica Ottolina Ludovica Bartiromo Paolo Cavoretto Carolina Dolci Rosalba Lembo Matteo Schimberni Luca Valsecchi Paola Viganò Massimo Candiani Gestational diabetes mellitus (GDM) is a metabolic complication associated with adverse outcomes for mother and fetus....
Sun Oct 11, 2020 03:00
Nutrients, Vol. 12, Pages 3093: Evolution of Resting Energy Expenditure, Respiratory Quotient, and Adiposity in Infants Recovering from Corrective Surgery of Major Congenital Gastrointestinal Tract Anomalies: A Cohort Study Nutrients doi: 10.3390/nu12103093 Authors: Luís Pereira-da-Silva Susana Barradas Ana Catarina Moreira Marta Alves Ana Luisa Papoila Daniel Virella Gonçalo Cordeiro-Ferreira This cohort study describes the evolution of resting energy expenditure (REE),...
Sun Oct 11, 2020 03:00
Nutrients, Vol. 12, Pages 3095: Quercetin Intervention Alleviates Offspring’s Oxidative stress, Inflammation, and Tight Junction Damage in the Colon Induced by Maternal Fine Particulate Matter (PM2.5) Exposure through the Reduction of Bacteroides Nutrients doi: 10.3390/nu12103095 Authors: Liu Zhou Qin Yu Li Chen Xu The influences of maternal fine particulate matter (PM2.5) exposure on intestinal oxidative stress, inflammation, tight junctions, and gut microbiota...
Sun Oct 11, 2020 03:00
Nutrients, Vol. 12, Pages 3086: The Effect of Fermented Porcine Placental Extract on Fatigue-Related Parameters in Healthy Adults: A Double-Blind, Randomized, Placebo-Controlled Trial Nutrients doi: 10.3390/nu12103086 Authors: Yoon Han Hwang Lee Kim Kim Kim Song : Background: Fatigue is one of the major health conditions induced by excessive stress or abnormal immune function or defective antioxidant systems. Placental extract has been reported to have various...
Sun Oct 11, 2020 03:00
Nutrients, Vol. 12, Pages 3088: Endoplasmic Reticulum Stress Affects Cholesterol Homeostasis by Inhibiting LXRα Expression in Hepatocytes and Macrophages Nutrients doi: 10.3390/nu12103088 Authors: Tian Wang Yiyang Zhao Zhongsheng You Xiatian Li Mingdi Xiong Hua Li Nianlong Yan Atherosclerosis (AS) is the most common cardiovascular disease, and reverse cholesterol transport (RCT) plays an important role in maintaining cholesterol homeostasis. Both endoplasmic reticulum...
Sun Oct 11, 2020 03:00
Nutrients, Vol. 12, Pages 3089: Daily Oral Administration of Protease-Treated Royal Jelly Protects Against Denervation-Induced Skeletal Muscle Atrophy Nutrients doi: 10.3390/nu12103089 Authors: Tomohiko Shirakawa Aki Miyawaki Takuma Matsubara Nobuaki Okumura Hideto Okamoto Naoya Nakai Thira Rojasawasthien Kazumasa Morikawa Asako Inoue Akino Goto Ayako Washio Toshiyuki Tsujisawa Tatsuo Kawamoto Shoichiro Kokabu Honeybees produce royal jelly (RJ)...
Sun Oct 11, 2020 03:00
Nutrients, Vol. 12, Pages 3090: Daily Consumption of Coffee and Eating Bread at Breakfast Time Is Associated with Lower Visceral Adipose Tissue and with Lower Prevalence of Both Visceral Obesity and Metabolic Syndrome in Japanese Populations: A Cross-Sectional Study Nutrients doi: 10.3390/nu12103090 Authors: Teruhide Koyama Mizuho Maekawa Etsuko Ozaki Nagato Kuriyama Ritei Uehara Background: The study aimed to investigate the association between daily consumption of coffee...
Sun Oct 11, 2020 03:00
Nutrients, Vol. 12, Pages 3087: Why Are Branched-Chain Amino Acids Increased in Starvation and Diabetes? Nutrients doi: 10.3390/nu12103087 Authors: Milan Holeček Branched-chain amino acids (BCAAs; valine, leucine, and isoleucine) are increased in starvation and diabetes mellitus. However, the pathogenesis has not been explained. It has been shown that BCAA catabolism occurs mostly in muscles due to high activity of BCAA aminotransferase, which converts BCAA and α-ketoglutarate...
Sun Oct 11, 2020 03:00
Nutrients, Vol. 12, Pages 3092: Dose–Response Relationship between Western Diet and Being Overweight among Teachers in Malaysia Nutrients doi: 10.3390/nu12103092 Authors: Jui Yee Eng Foong Ming Moy Awang Bulgiba Sanjay Rampal The rising prevalence of overweight and obesity is partly due to nutrition transition. The reported association between dietary patterns and overweight/obesity has been controversial because of inconsistent results and weak observed associations. Although...
Sun Oct 11, 2020 03:00
Nutrients, Vol. 12, Pages 3085: Macroalgae—A Sustainable Source of Chemical Compounds with Biological Activities Nutrients doi: 10.3390/nu12103085 Authors: Elena-Suzana Biris-Dorhoi Delia Michiu Carmen R. Pop Ancuta M. Rotar Maria Tofana Oana L. Pop Sonia A. Socaci Anca C. Farcas Nowadays, one of the most important research directions that concerns the scientific world is to exploit the earth’s resources in a sustainable way. Considering the increasing...
Sun Oct 11, 2020 03:00
Nutrients, Vol. 12, Pages 3084: Nutrition Behaviors in Polish Adults before and during COVID-19 Lockdown Nutrients doi: 10.3390/nu12103084 Authors: Błaszczyk-Bębenek Jagielski Bolesławska Jagielska Nitsch-Osuch Kawalec Unexpected isolation, which has not yet been seen on a global scale, has created the conditions for evaluating nutrition in a situation of reduced spatial activity. The study aimed to assess the influence of lockdown on selected eating habits of Polish...
Sat Oct 10, 2020 03:00
Nutrients, Vol. 12, Pages 3082: Relationship between Wine Consumption, Diet and Microbiome Modulation in Alzheimer’s Disease Nutrients doi: 10.3390/nu12103082 Authors: Moreno-Arribas Bartolomé Peñalvo Pérez-Matute Motilva Alzheimer’s disease (AD) is a progressive neurodegenerative disorder leading to the most common form of dementia in elderly people. Modifiable dietary and lifestyle factors could either accelerate or ameliorate the aging process and the risk...
Sat Oct 10, 2020 03:00
Nutrients, Vol. 12, Pages 3083: Telephone-Delivered Dietary Intervention in Patients with Age-Related Macular Degeneration: 3-Month Post-Intervention Findings of a Randomised Controlled Trial Nutrients doi: 10.3390/nu12103083 Authors: Tang Mitchell Liew Burlutsky Flood Gopinath There is an evidence–practice gap between the dietary recommendations for age-related macular degeneration (AMD) presented in the literature and those practiced by patients. This...
Sat Oct 10, 2020 03:00
Nutrients, Vol. 12, Pages 3079: Beneficial Role of Replacing Dietary Saturated Fatty Acids with Polyunsaturated Fatty Acids in the Prevention of Sarcopenia: Findings from the NU-AGE Cohort Nutrients doi: 10.3390/nu12103079 Authors: Diego Montiel-Rojas Aurelia Santoro Andreas Nilsson Claudio Franceschi Miriam Capri Alberto Bazzocchi Giuseppe Battista Lisette C. P. G. M. de Groot Edith J. M. Feskens Agnes A.M. Berendsen Agata Bialecka-Debek Olga Surala Barbara...
Fri Oct 09, 2020 03:00
Nutrients, Vol. 12, Pages 3080: Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human Nutrients doi: 10.3390/nu12103080 Authors: Hye Jin Jee Sang Goo Lee Katrina Joy Bormate Yi-Sook Jung Caffeine occurs naturally in various foods, such as coffee, tea, and cocoa, and it has been used safely as a mild stimulant for a long time. However, excessive caffeine consumption (1~1.5 g/day) can cause caffeine poisoning (caffeinism),...
Fri Oct 09, 2020 03:00
Nutrients, Vol. 12, Pages 3081: Brief Hospital Supervision of Exercise and Diet During Adjuvant Breast Cancer Therapy Is Not Enough to Relieve Fatigue: A Multicenter Randomized Controlled Trial Nutrients doi: 10.3390/nu12103081 Authors: William Jacot Antoine Arnaud Marta Jarlier Claudia Lefeuvre-Plesse Philippe Dalivoust Pierre Senesse Ahmed Azzedine Olivier Tredan Sophie Sadot-Lebouvier Sébastien Mas Marion Carayol Jean-Pierre Bleuse Sophie Gourgou Chloé...
Fri Oct 09, 2020 03:00
Nutrients, Vol. 12, Pages 3078: Demographic, Behavioural and Anthropometric Correlates of Food Liking: A Cross-sectional Analysis of Young Adults Nutrients doi: 10.3390/nu12103078 Authors: K.M. Livingstone H. Pnosamy LJ. Riddell S. Cicerale The degree to which foods are liked or disliked is associated with dietary intake and health behaviours. However, most food liking research has focused on single foods and nutrients and few studies have examined associations with demographics...
Fri Oct 09, 2020 03:00
Nutrients, Vol. 12, Pages 3077: Mikania micrantha Extract Inhibits HMG-CoA Reductase and ACAT2 and Ameliorates Hypercholesterolemia and Lipid Peroxidation in High Cholesterol-Fed Rats Nutrients doi: 10.3390/nu12103077 Authors: Azlinda Ibrahim Nurul Husna Shafie Norhaizan Mohd Esa Siti Raihanah Shafie Hasnah Bahari Maizaton Atmadini Abdullah The present study aimed to determine the effect of an ethyl acetate extract of Mikania micrantha stems (EAMMS) in hypercholesterolemia-induced...
Fri Oct 09, 2020 03:00
Nutrients, Vol. 12, Pages 3076: What Do Polish Parents and Caregivers Think of Dietary Supplements for Children Aged 3–12? Nutrients doi: 10.3390/nu12103076 Authors: Agnieszka Piekara Małgorzata Krzywonos Monika Kaczmarczyk Background: The aim of this study was to specify the amounts and the types of dietary supplements (DS) taken by children and define the attitudes of caregivers towards DS and towards administering them to children aged 3–12. An analysis of the reasons...
Fri Oct 09, 2020 03:00
Pathogens, Vol. 9, Pages 832: Clinical Characteristics of Acute Hepatitis E and Their Correlation with HEV Genotype 3 Subtypes in Italy Pathogens doi: 10.3390/pathogens9100832 Authors: Claudia Minosse Elisa Biliotti Daniele Lapa Alessia Rianda Mauro Marchili Ilaria Luzzitelli Maria Rosaria Capobianchi Fiona McPhee Anna Rosa Garbuglia Gianpiero D’Offizi Genotype 3 (GT3) is responsible for most European autochthonous hepatitis E virus (HEV) infections. This study...
Sun Oct 11, 2020 03:00
Pathogens, Vol. 9, Pages 831: Bacteriophage Cocktail for the Prevention of Multiple-Antibiotic-Resistant and Mono-Phage-Resistant Vibrio coralliilyticus Infection in Pacific Oyster (Crassostrea gigas) Larvae Pathogens doi: 10.3390/pathogens9100831 Authors: Kim Jun Giri Kim Kim Kwon Lee Chi Park Vibrio coralliilyticus (V. coralliilyticus) is a pathogen that causes mass mortality in marine bivalve hatcheries worldwide. In this study, we used a bacteriophage...
Sun Oct 11, 2020 03:00
Pathogens, Vol. 9, Pages 828: Increased Serum IgG4 Associates with Asthma and Tissue Eosinophilia in Chronic Rhinosinusitis Patients Pathogens doi: 10.3390/pathogens9100828 Authors: Ramezanpour Hu Lau Liu De Silva Bolt Patterson Rischmueller Psaltis Wormald Lester Vreugde Chronic Rhinosinusitis (CRS) is a multifactorial disease where microorganisms’ innate and adaptive immunity can play a role. This study assessed the total IgG,...
Sat Oct 10, 2020 03:00
Pathogens, Vol. 9, Pages 830: Feed Supplementation with a Commercially Available Probiotic Solution Does Not Alter the Composition of the Microbiome in the Biofilters of Recirculating Aquaculture Systems Pathogens doi: 10.3390/pathogens9100830 Authors: Simon Menanteau-Ledouble Rui A. Gonçalves Mansour El-Matbouli Recirculating aquaculture relies on the treatment of ammonia compounds from the water by a bacterial flora growing inside biofilters. Another increasingly common practice...
Sat Oct 10, 2020 03:00
Pathogens, Vol. 9, Pages 829: Genomic Diversity and Hotspot Mutations in 30,983 SARS-CoV-2 Genomes: Moving Toward a Universal Vaccine for the “Confined Virus”? Pathogens doi: 10.3390/pathogens9100829 Authors: Tarek Alouane Meriem Laamarti Abdelomunim Essabbar Mohammed Hakmi El Mehdi Bouricha M. W. Chemao-Elfihri Souad Kartti Nasma Boumajdi Houda Bendani Rokia Laamarti Fatima Ghrifi Loubna Allam Tarik Aanniz Mouna Ouadghiri Naima El Hafidi Rachid...
Sat Oct 10, 2020 03:00
Pathogens, Vol. 9, Pages 827: Extracts from Six Native Plants of the Yucatán Peninsula Hinder Mycelial Growth of Fusarium equiseti and F. oxysporum, Pathogens of Capsicum chinense Pathogens doi: 10.3390/pathogens9100827 Authors: Cruz-Cerino Cristóbal-Alejo Ruiz-Carrera Carnevali Vera-Ku Martín Reyes Gamboa-Angulo Fusarium equiseti strain FCHE and Fusarium oxysporum strain FCHJ were isolated from the roots of wilting habanero pepper (Capsicum chinense Jacq.)...
Sat Oct 10, 2020 03:00
Pathogens, Vol. 9, Pages 826: Structural and Functional Analysis of BBA03, Borrelia burgdorferi Competitive Advantage Promoting Outer Surface Lipoprotein Pathogens doi: 10.3390/pathogens9100826 Authors: Fridmanis Bobrovs Brangulis Tārs Jaudzems BBA03 is a Borrelia burgdorferi outer surface lipoprotein encoded on one of the most conserved plasmids in Borrelia genome, linear plasmid 54 (lp54). Although many of its genes have been identified as contributing or essential...
Fri Oct 09, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 299: The Principles, Mechanisms, and Benefits of Unconventional Agents in the Treatment of Biofilm Infection Pharmaceuticals doi: 10.3390/ph13100299 Authors: Jasminka Talapko Ivana Škrlec Today, researchers are looking at new ways to treat severe infections caused by resistance to standard antibiotic therapy. This is quite challenging due to the complex and interdependent relationships involved: the cause of infection–the patient–antimicrobial...
Sat Oct 10, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 300: Characterization of iRGD-Ligand Modified Arginine-Histidine-Rich Peptides for Nucleic Acid Therapeutics Delivery to αvβ3 Integrin-Expressing Cancer Cells Pharmaceuticals doi: 10.3390/ph13100300 Authors: Egorova Selutin Maretina Selkov Baranov Kiselev Efficient and specific delivery of nucleic acid (NA) therapeutics to tumor cells is extremely important for cancer gene therapy. Various therapeutic strategies include delivery of...
Sat Oct 10, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 298: Impact of S1P Mimetics on Mesenteric Ischemia/Reperfusion Injury Pharmaceuticals doi: 10.3390/ph13100298 Authors: Potì Giorgio Zini Nofer Vivo Palese Ballabeni Barocelli Bertoni Mesenteric ischemia/reperfusion (I/R), following the transient deprivation of blood flow to the gut, triggers an acute flogistic process involving the disruption of endothelial and epithelial barriers integrity, the activation of immune cells,...
Fri Oct 09, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 297: Disruption of Cholinergic Circuits as an Area for Targeted Drug Treatment of Alzheimer’s Disease: In Vivo Assessment of Short-Term Plasticity in Rat Brain Pharmaceuticals doi: 10.3390/ph13100297 Authors: Vergine Chavushyan Ani Soghomonyan Gohar Karapetyan Karen Simonyan Konstantin Yenkoyan The search for new therapeutics for the treatment of Alzheimer’s disease (AD) is still in progress. Aberrant pathways of synaptic transmission...
Fri Oct 09, 2020 03:00
Pharmaceutics, Vol. 12, Pages 958: Multivariate Analytical Approaches to Identify Key Molecular Properties of Vehicles, Permeants and Membranes That Affect Permeation through Membranes Pharmaceutics doi: 10.3390/pharmaceutics12100958 Authors: Omaima N. Najib Stewart B. Kirton Gary P. Martin Michelle J. Botha Al-Sayed Sallam Darragh Murnane There has been considerable recent interest in employing computer models to investigate the relationship between the structure of a...
Sun Oct 11, 2020 03:00
Pharmaceutics, Vol. 12, Pages 957: Mesoporous Silica Nanoparticles as Theranostic Antitumoral Nanomedicines Pharmaceutics doi: 10.3390/pharmaceutics12100957 Authors: Alejandro Baeza Maria Vallet-Regí Nanoparticles have become a powerful tool in oncology not only as carrier of the highly toxic chemotherapeutic drugs but also as imaging contrast agents that provide valuable information about the state of the disease and its progression. The enhanced permeation and retention effect for...
Sun Oct 11, 2020 03:00
Pharmaceutics, Vol. 12, Pages 956: The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells Pharmaceutics doi: 10.3390/pharmaceutics12100956 Authors: Usama A. Fahmy Hibah M. Aldawsari Shaimaa M. Badr-Eldin Osama A. A. Ahmed Nabil A. Alhakamy Helal H. Alsulimani Filippo Caraci Giuseppe Caruso Febuxostat (FBX) is a drug able to inhibit xanthine oxidase and reduce uric acid production commonly...
Sun Oct 11, 2020 03:00
Pharmaceutics, Vol. 12, Pages 959: Pharmaceutical Hydrates Analysis—Overview of Methods and Recent Advances Pharmaceutics doi: 10.3390/pharmaceutics12100959 Authors: Jurczak Mazurek Szeleszczuk Pisklak Zielińska-Pisklak This review discusses a set of instrumental and computational methods that are used to characterize hydrated forms of APIs (active pharmaceutical ingredients). The focus has been put on highlighting advantages as well as on presenting some limitations...
Sun Oct 11, 2020 03:00
Pharmaceutics, Vol. 12, Pages 955: Therapeutic Interventions into Innate Immune Diseases by Means of Aptamers Pharmaceutics doi: 10.3390/pharmaceutics12100955 Authors: Yasmeen Seo Javaid Kim Choi The immune system plays a crucial role in the body’s defense system against various pathogens, such as bacteria, viruses, and parasites, as well as recognizes non-self- and self-molecules. The innate immune system is composed of special receptors known as pattern recognition...
Sun Oct 11, 2020 03:00
Pharmaceutics, Vol. 12, Pages 954: Effective Dispensing Methods for Loading Drugs Only to the Tip of DNA Microneedles Pharmaceutics doi: 10.3390/pharmaceutics12100954 Authors: Bok Zhao Hwang Kang Jeon Ko Jeong Song Lim Jeong Here, we propose a novel and simple method to efficiently capture the diffusion of fluorescein isothiocyanate (FITC)-dextran from a biocompatible substance and load the drug only to the tip of DNA microneedles. A dispensing and...
Sat Oct 10, 2020 03:00
Pharmaceutics, Vol. 12, Pages 951: Gellan Gum Promotes the Differentiation of Enterocytes from Human Induced Pluripotent Stem Cells Pharmaceutics doi: 10.3390/pharmaceutics12100951 Authors: Shimeng Qiu Tomoki Kabeya Isamu Ogawa Shiho Anno Hisato Hayashi Tatsuro Kanaki Tadahiro Hashita Takahiro Iwao Tamihide Matsunaga The evaluation of drug pharmacokinetics in the small intestine is critical for developing orally administered drugs. Caucasian colon adenocarcinoma...
Sat Oct 10, 2020 03:00
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