Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. cAMP response element binding protein (CREB)-regulated transcription coactivator 2 (CRTC2), a member of the novel CRTC family of transcriptional coactivators that activates basic leucine zipper transcription factors, including CREB, is overexpressed in many carcinomas, including colon cancer. Phosphorylation of CRTC2 protein at different residues is important for its subcellular localization and activity. However,...
Thu Oct 01, 2020 12:54
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020.
Thu Oct 01, 2020 12:52
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Neuroblastoma (NB) is a rare type of cancer but frequently occurred in children. However, it is still unclear whether circular RNAs (circRNAs) play key roles in NB tumorigenesis or progression. In this study, we identified 39,022 circRNAs across the 39 neuroblastoma and 2 normal cell lines. With the gene and circRNA expression data, we classified the NB cell lines, identified and characterized the functional circRNAs...
Thu Oct 01, 2020 12:31
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