Antibiotics, Vol. 8, Pages 268: Development, Validation, and Stability Assessment Application of RP-HPLC-DAD Method for Quantification of Ampicillin in Total Parenteral Nutrition Admixtures Antibiotics doi: 10.3390/antibiotics8040268 Authors: Maciej Stawny Aleksandra Gostyńska Katarzyna Dettlaff Anna Jelińska Marta Kościelniak Magdalena Ogrodowczyk Background: The administration of total parenteral nutrition (TPN) is a common procedure in intensive care units, where the...
Sun Dec 15, 2019 02:00
Antibiotics, Vol. 8, Pages 267: Exclusive Production of Gentamicin C1a from Micromonospora purpurea by Metabolic Engineering Antibiotics doi: 10.3390/antibiotics8040267 Authors: Zeng Wei Xianai Shi Rong Lian Weibin Wang Wenrong Hong Shaobin Guo Gentamicin C1a is an important precursor to the synthesis of etimicin, a potent antibiotic. Wild type Micromonospora purpurea Gb1008 produces gentamicin C1a, besides four other gentamicin C components: C1, C2, C2a, and C2b. While...
Sat Dec 14, 2019 02:00
Antibiotics, Vol. 8, Pages 266: The Inc FII Plasmid and its Contribution in the Transmission of blaNDM-1 and blaKPC-2 in Klebsiella pneumoniae in Egypt Antibiotics doi: 10.3390/antibiotics8040266 Authors: Mohamed Ali Waly Halby El-Baky The emergence of blaKPC-2 and blaNDM-1 producing Klebsiella pneumoniae represents a great problem in many Egyptian hospitals. One hundred and twenty-six K. pneumoniae isolates from patients admitted to Assiut University Hospital were identified...
Fri Dec 13, 2019 02:00
Antibiotics, Vol. 8, Pages 265: Short Chain Fatty Acids Commonly Produced by Gut Microbiota Influence Salmonella enterica Motility, Biofilm Formation, and Gene Expression Antibiotics doi: 10.3390/antibiotics8040265 Authors: Alexandre Lamas Patricia Regal Beatriz Vázquez Alberto Cepeda Carlos Manuel Franco Short chain fatty acids (SCFAs) are commonly produced by healthy gut microbiota and they have a protective role against enteric pathogens. SCFAs also have direct antimicrobial...
Fri Dec 13, 2019 02:00
Antibiotics, Vol. 8, Pages 264: Factors Influencing the Onset of Intra- and Post- Operative Complications Following Tooth Exodontia: Retrospective Survey on 1701 Patients Antibiotics doi: 10.3390/antibiotics8040264 Authors: Erica Vettori Fulvia Costantinides Vanessa Nicolin Roberto Rizzo Giuseppe Perinetti Michele Maglione Roberto Di Lenarda Complications after tooth extraction may occur because of several factors correlated to the patient’s medical history,...
Fri Dec 13, 2019 02:00
Antibiotics, Vol. 8, Pages 263: Knowledge, Perceptions and Practices of Community Pharmacists Towards Antimicrobial Stewardship: A Systematic Scoping Review Antibiotics doi: 10.3390/antibiotics8040263 Authors: Saha Barton Promite Mazza The scope of antimicrobial stewardship (AMS) surveys on community pharmacists (CPs) is uncertain. This study examines the breadth and quality of AMS survey tools measuring the stewardship knowledge, perceptions and practices (KPP) of CPs and...
Thu Dec 12, 2019 02:00
Antibiotics, Vol. 8, Pages 262: Tracing Penicillin Movement in Citrus Plants Using Fluorescence-Labeled Penicillin Antibiotics doi: 10.3390/antibiotics8040262 Authors: Killiny Gonzalez-Blanco Santos-Ortega Al-Rimawi Levy Hijaz Albrecht Batuman Huánglóngbìng (HLB), citrus greening, is one of the most destructive diseases of citrus plants worldwide. In North America, HLB is caused by the phloem-limited bacterium Candidatus Liberibacter...
Thu Dec 12, 2019 02:00
Antioxidants, Vol. 8, Pages 646: Phenolic Constituents of Chrysophyllum oliviforme L. Leaf Down-Regulate TGF-β Expression and Ameliorate CCl4-Induced Liver Fibrosis: Evidence from In Vivo and In Silico Studies Antioxidants doi: 10.3390/antiox8120646 Authors: Seham S. El-Din El-Hawary Soheir M. El Zalabani Nabil M. Selim Marwa A. Ibrahim Fatma A. Wahba Shymaa A. El Badawy Nariman El Sayed Mahdy Aziz Yasri Mansour Sobeh The prevalence of hepatic diseases globally...
Sun Dec 15, 2019 02:00
Antioxidants, Vol. 8, Pages 645: Ascorbic Acid—The Little-Known Antioxidant in Woody Plants Antioxidants doi: 10.3390/antiox8120645 Authors: Karolina Bilska Natalia Wojciechowska Shirin Alipour Ewa Marzena Kalemba Reactive oxygen species (ROS) are constantly produced by metabolically active plant cells. The concentration of ROS may determine their role, e.g., they may participate in signal transduction or cause oxidative damage to various cellular components. To ensure cellular...
Sat Dec 14, 2019 02:00
Antioxidants, Vol. 8, Pages 644: Protective Effects of Unsaponifiable Matter from Perilla Seed Meal on UVB-induced Damages and the Underlying Mechanisms in Human Skin Fibroblasts Antioxidants doi: 10.3390/antiox8120644 Authors: Hana Lee Jeehye Sung Younghwa Kim Heon Sang Jeong Junsoo Lee Unsaponifiable matter (USM) from perilla seed meal contains numerous phytochemicals, including tocopherols, phytosterols, squalene, and policosanols, that exhibit antioxidant and health-promoting...
Fri Dec 13, 2019 02:00
Antioxidants, Vol. 8, Pages 643: Effects of Very Low Calorie Ketogenic Diet on the Orexinergic System, Visceral Adipose Tissue, and ROS Production Antioxidants doi: 10.3390/antiox8120643 Authors: Anna Valenzano Rita Polito Valentina Trimigno Antonella Di Palma Fiorenzo Moscatelli Gaetano Corso Francesco Sessa Monica Salerno Angelo Montana Nunzio Di Nunno Marinella Astuto Aurora Daniele Marco Carotenuto Giovanni Messina Giuseppe Cibelli Vincenzo...
Fri Dec 13, 2019 02:00
Antioxidants, Vol. 8, Pages 642: Dietary Antioxidants: Micronutrients and Antinutrients in Physiology and Pathology Antioxidants doi: 10.3390/antiox8120642 Authors: Ilaria Peluso This Special Issue aimed to clarify the distinction between micronutrients and antinutrients and their different roles in physiology and pathology, considering the European Food Safety Authority (EFSA) criteria for health claims [...]
Fri Dec 13, 2019 02:00
Antioxidants, Vol. 8, Pages 641: Assessment of Subcellular ROS and NO Metabolism in Higher Plants: Multifunctional Signaling Molecules Antioxidants doi: 10.3390/antiox8120641 Authors: Kohli Khanna Bhardwaj Abd_Allah Ahmad Corpas Reactive oxygen species (ROS) and nitric oxide (NO) are produced in all aerobic life forms under both physiological and adverse conditions. Unregulated ROS/NO generation causes nitro-oxidative damage, which has a detrimental impact on the...
Thu Dec 12, 2019 02:00
Antioxidants, Vol. 8, Pages 639: Manganese Porphyrin-Based SOD Mimetics Produce Polysulfides from Hydrogen Sulfide Antioxidants doi: 10.3390/antiox8120639 Authors: Kenneth R. Olson Yan Gao Faihaan Arif Shivali Patel Xiaotong Yuan Varun Mannam Scott Howard Ines Batinic-Haberle Jon Fukuto Magdalena Minnion Martin Feelisch Karl D. Straub Manganese-centered porphyrins (MnPs), MnTE-2-PyP5+ (MnTE), MnTnHex-2-PyP5+ (MnTnHex), and MnTnBuOE-2-PyP5+ (MnTnBuOE)...
Thu Dec 12, 2019 02:00
Antioxidants, Vol. 8, Pages 640: The Influence of Light on Reactive Oxygen Species and NF-кB in Disease Progression Antioxidants doi: 10.3390/antiox8120640 Authors: Naresh Kumar Rajendran Blassan P. George Rahul Chandran Ivan Mfouo Tynga Nicolette Houreld Heidi Abrahamse Reactive oxygen species (ROS) are important secondary metabolites that play major roles in signaling pathways, with their levels often used as analytical tools to investigate various cellular scenarios....
Thu Dec 12, 2019 02:00
Atmosphere, Vol. 10, Pages 815: Observed Changes in Temperature and Precipitation Extremes Over the Yarlung Tsangpo River Basin during 1970–2017 Atmosphere doi: 10.3390/atmos10120815 Authors: Chunyu Liu Yungang Li Xuan Ji Xian Luo Mengtao Zhu Twenty-five climate indices based on daily maximum and minimum temperature and precipitation at 15 meteorological stations were examined to investigate changes in temperature and precipitation extremes over the Yarlung Tsangpo River...
Sun Dec 15, 2019 02:00
Atmosphere, Vol. 10, Pages 814: Remote Sensing of Clouds Atmosphere doi: 10.3390/atmos10120814 Authors: Filomena Romano This special issue collects four original and review articles dealing with different cloud aspects, from microphysical properties to macrophysical features [...]
Sun Dec 15, 2019 02:00
Atmosphere, Vol. 10, Pages 813: The Relationship between the Wintertime Cold Extremes over East Asia with Large-Scale Atmospheric and Oceanic Teleconnections Atmosphere doi: 10.3390/atmos10120813 Authors: Yang Xie Gao The influence of large-scale teleconnection patterns, Western Pacific (WP), Arctic Oscillation (AO) and El Niño-Southern Oscillation (ENSO), on the minimum surface air temperature (Tmin) anomalies and extremes over East Asia during the boreal winter...
Sat Dec 14, 2019 02:00
Atmosphere, Vol. 10, Pages 812: Discontinuities in the Ozone Concentration Time Series from MERRA 2 Reanalysis Atmosphere doi: 10.3390/atmos10120812 Authors: Peter Krizan Michal Kozubek Jan Lastovicka Artificial discontinuities in time series are a great problem for trend analysis because they influence the values of the trend and its significance. The aim of this paper is to investigate their occurrence in the Modern-Era Retrospective analysis for Research and Applications, version...
Sat Dec 14, 2019 02:00
Atmosphere, Vol. 10, Pages 811: Sodar Observation of the ABL Structure and Waves over the Black Sea Offshore Site Atmosphere doi: 10.3390/atmos10120811 Authors: Vasily Lyulyukin Margarita Kallistratova Daria Zaitseva Dmitry Kuznetsov Arseniy Artamonov Irina Repina Igor Petenko Rostislav Kouznetsov Artem Pashkin Sodar investigations of the breeze circulation and vertical structure of the atmospheric boundary layer (ABL) were carried out in the coastal zone of the...
Sat Dec 14, 2019 02:00
Atmosphere, Vol. 10, Pages 810: Convective Shower Characteristics Simulated with the Convection-Permitting Climate Model COSMO-CLM Atmosphere doi: 10.3390/atmos10120810 Authors: Purr Brisson Ahrens This paper evaluates convective precipitation as simulated by the convection-permitting climate model (CPM) Consortium for Small-Scale Modeling in climate mode (COSMO-CLM) (with 2.8 km grid-spacing) over Germany in the period 2001–2015. Characteristics of simulated convective...
Fri Dec 13, 2019 02:00
Atmosphere, Vol. 10, Pages 809: Rainfall and Flooding in Coastal Tourist Areas of the Canary Islands (Spain) Atmosphere doi: 10.3390/atmos10120809 Authors: López Díez Máyer Suárez Díaz Pacheco Dorta Antequera Coastal spaces exploited for tourism tend to be developed rapidly and with a desire to maximise profit, leading to diverse environmental problems, including flooding. As the origin of flood events is usually associated with intense precipitation episodes, this study...
Fri Dec 13, 2019 02:00
Atmosphere, Vol. 10, Pages 808: Cloud Occurrence Frequency at Puy de Dôme (France) Deduced from an Automatic Camera Image Analysis: Method, Validation, and Comparisons with Larger Scale Parameters Atmosphere doi: 10.3390/atmos10120808 Authors: Jean-Luc Baray Asmaou Bah Philippe Cacault Karine Sellegri Jean-Marc Pichon Laurent Deguillaume Nadège Montoux Vincent Noel Geneviève Seze Franck Gabarrot Guillaume Payen Valentin Duflot We present a simple algorithm...
Fri Dec 13, 2019 02:00
Atmosphere, Vol. 10, Pages 807: On the Constellation Design of Multi-GNSS Reflectometry Mission Using the Particle Swarm Optimization Algorithm Atmosphere doi: 10.3390/atmos10120807 Authors: Yi Han Jia Luo Xiaohua Xu Due to the great success of the CYclone Global Navigation Satellite System (CYGNSS) mission, the follow-on GNSS Reflectometry (GNSS-R) missions are being planned. In the perceivable future, signal sources for GNSS-R missions can originate from multiple global navigation...
Fri Dec 13, 2019 02:00
Atmosphere, Vol. 10, Pages 806: Relating Moisture Transport to Stable Water Vapor Isotopic Variations of Ambient Wintertime along the Western Coast of Korea Atmosphere doi: 10.3390/atmos10120806 Authors: Kim Han Hur Yoshimura Lee Atmospheric water vapor transfers energy, causes meteorological phenomena and can be modified by climate change in the western coast region of Korea. In Korea, previous studies have utilized precipitation isotopic compositions in the water cycle...
Thu Dec 12, 2019 02:00
Atmosphere, Vol. 10, Pages 805: Impact of Effective Roughness Length on Mesoscale Meteorological Simulations over Heterogeneous Land Surfaces in Taiwan Atmosphere doi: 10.3390/atmos10120805 Authors: Cheng Lin Wang Tsai Tsuang Lin The Weather Research and Forecasting (WRF) modeling system obtains the aerodynamic roughness length (z0) from a land use (LU) lookup table. The effective aerodynamic roughness length (z0eff) was estimated for the island of Taiwan by considering...
Thu Dec 12, 2019 02:00
Atmosphere, Vol. 10, Pages 803: Hierarchical Modeling of Solar System Planets with Isca Atmosphere doi: 10.3390/atmos10120803 Authors: Stephen I. Thomson Geoffrey K. Vallis We describe the use of Isca for the hierarchical modeling of Solar System planets, with particular attention paid to Earth, Mars, and Jupiter. Isca is a modeling framework for the construction and use of models of planetary atmospheres at varying degrees of complexity, from featureless model planets with an atmosphere...
Thu Dec 12, 2019 02:00
Atmosphere, Vol. 10, Pages 802: Evaluation of the Rossby Centre Regional Climate Model Rainfall Simulations over West Africa Using Large-Scale Spatial and Temporal Statistical Metrics Atmosphere doi: 10.3390/atmos10120802 Authors: Gnim Tchalim Gnitou Tinghuai Ma Guirong Tan Brian Ayugi Isaac Kwesi Nooni Alia Alabdulkarim Yuan Tian Climate models are usually evaluated to understand how well the modeled data reproduce specific application-related features. In Africa,...
Thu Dec 12, 2019 02:00
Atmosphere, Vol. 10, Pages 804: Evaluation of Near-Surface Wind Speed Changes during 1979 to 2011 over China Based on Five Reanalysis Datasets Atmosphere doi: 10.3390/atmos10120804 Authors: Jiang Yu Tianjun Zhou Zhihong Jiang Liwei Zou Wind speed data derived from reanalysis datasets has been used in the plan and design of wind farms in China, but the quality of these kinds of data over China remains unknown. In this study, the performances of five sets of reanalysis data, including...
Thu Dec 12, 2019 02:00
Behavioral Sciences, Vol. 9, Pages 159: Strategies of Speech Interaction between Adults and Preschool Children with Typical and Atypical Development Behavioral Sciences doi: 10.3390/bs9120159 Authors: Elena Lyakso Olga Frolova Aleksey Grigorev Viktor Gorodnyi Aleksandr Nikolaev The goal of this research is to study the speech strategies of adults’ interactions with 4–7-year-old children. The participants are “mother–child”...
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Behavioral Sciences, Vol. 9, Pages 158: Experimental Research into Conscious Self-Regulation in First-Graders with Developmental Delay Behavioral Sciences doi: 10.3390/bs9120158 Authors: Babkina The underdeveloped conscious self-regulation of actions plays a primary role in the disorder-related character of children with developmental delay (DD). This study aimed to analyze and systematize specific occurrences of conscious self-regulation in children’s DD-affected cognitive...
Sun Dec 15, 2019 02:00
Behavioral Sciences, Vol. 9, Pages 154: How Decisiveness, Self-Efficacy, Curiosity and Independent and Interdependent Self-Construals Are Related to Future Hopefulness among Senior Students Behavioral Sciences doi: 10.3390/bs9120154 Authors: Hakan Remzi Öztekin Fatih Bayraktar Hope is a future-oriented reasoning that influences psychological assets of individuals. A hopeful standing towards the future can positively influence individual well-being. Different standings in terms of...
Sat Dec 14, 2019 02:00
Behavioral Sciences, Vol. 9, Pages 156: Examining the Convergent Validity of the Triarchic Psychopathy Measure Using a Sample of Incarcerated and on Probation Lithuanian Juveniles Behavioral Sciences doi: 10.3390/bs9120156 Authors: Laura Ustinavičiūtė Alfredas Laurinavičius Virginija Klimukienė Ilona Laurinaitytė Mykolas Baltrūnas The Triarchic Psychopathy Measure (TriPM) is based on the triarchic psychopathy model proposed by Patrick, Fowles, and Krueger in 2009. This paper...
Sat Dec 14, 2019 02:00
Behavioral Sciences, Vol. 9, Pages 157: Designing a Scale to Assess Dialectical Thinking: Link to ECERS-R Items Behavioral Sciences doi: 10.3390/bs9120157 Authors: Nikolay Veraksa Olga Shiyan Ekaterina Sviridova Dialectical thinking is gaining wide circulation as part of personal and social preschool child development in modern society, which makes all the more urgent the task of designing a tool to evaluate the extent to which the educational environment in a pre-school establishment...
Sat Dec 14, 2019 02:00
Behavioral Sciences, Vol. 9, Pages 155: Classification of Participants Based on Increase–Decrease Rate Model of Reaction Time to Personality Trait Words Behavioral Sciences doi: 10.3390/bs9120155 Authors: Kouhei Matsuda Emi Sato In this experiment, we tried to measure personality by reaction time (RT) to stimuli of personality trait words. There were interindividual and intraindividual differences in the factors that caused the reaction time to fluctuate. The intraindividual differences...
Sat Dec 14, 2019 02:00
Behavioral Sciences, Vol. 9, Pages 153: Parents’ Personality, Marriage Satisfaction, Stress, and Punishment of Children in the Family Behavioral Sciences doi: 10.3390/bs9120153 Authors: Mikhail Chumakov Daria Chumakova The objective of the research is to ascertain whether emotional and volitional characteristics of the individual affect the frequency of punishment in the family (for example, prohibition to watch TY for some time, pocket money reduction, request for an apology). These...
Thu Dec 12, 2019 02:00
Bioengineering, Vol. 6, Pages 114: Quantitative CPP Evaluation from Risk Assessment Using Integrated Process Modeling Bioengineering doi: 10.3390/bioengineering6040114 Authors: Daniel Borchert Thomas Zahel Yvonne E. Thomassen Christoph Herwig Diego A. Suarez-Zuluaga Risk assessments (RAs) are frequently conducted to assess the potential effect of process parameters (PPs) on product quality attributes (e.g., a critical quality attribute (CQA)). To evaluate the PPs criticality...
Fri Dec 13, 2019 02:00
Bioengineering, Vol. 6, Pages 113: Engineered 3D Polymer and Hydrogel Microenvironments for Cell Culture Applications Bioengineering doi: 10.3390/bioengineering6040113 Authors: Daniel Fan Urs Staufer Angelo Accardo The realization of biomimetic microenvironments for cell biology applications such as organ-on-chip, in vitro drug screening, and tissue engineering is one of the most fascinating research areas in the field of bioengineering. The continuous evolution of additive manufacturing...
Fri Dec 13, 2019 02:00
Biomedicines, Vol. 7, Pages 100: Engineering Requirements of a Herpes Simplex Virus Patient Registry: Discovery Phase of a Real-World Evidence Platform to Advance Pharmacogenomics and Personalized Medicine Biomedicines doi: 10.3390/biomedicines7040100 Authors: Svitlana Surodina Ching Lam Caroline de Cock Michelle van Velthoven Madison Milne-Ives Edward Meinert Comprehensive pharmacogenomic understanding requires both robust genomic and demographic data. Patient registries...
Sun Dec 15, 2019 02:00
Biomedicines, Vol. 7, Pages 99: Global Burden of Alcohol Use Disorders and Alcohol Liver Disease Biomedicines doi: 10.3390/biomedicines7040099 Authors: Jürgen Rehm Kevin D. Shield Alcohol use is a major risk factor for burden of mortality and morbidity. Alcoholic liver disease (ALD) and alcohol use disorders (AUDs) are important disease outcomes caused by alcohol use. We will describe the global mortality and burden of disease in disability-adjusted life years for ALD and AUDs, based...
Fri Dec 13, 2019 02:00
Biomedicines, Vol. 7, Pages 98: The Chemistry, Pharmacology and Therapeutic Potential of the Edible Mushroom Dictyophora indusiata (Vent ex. Pers.) Fischer (Synn. Phallus indusiatus) Biomedicines doi: 10.3390/biomedicines7040098 Authors: Habtemariam Dictyophora indusiata (Vent. Ex. Pers.) Fischer or Phallus indusiatus is an edible member of the higher mushroom phylum of Basidiomycetes. Known for its morphological elegance that gave it the names bridal veil fungus, veiled lady or queen...
Thu Dec 12, 2019 02:00
Biomolecules, Vol. 9, Pages 878: Hypertrophic Cardiomyopathy: An Overview of Genetics and Management
Biomolecules, Vol. 9, Pages 878: Hypertrophic Cardiomyopathy: An Overview of Genetics and Management Biomolecules doi: 10.3390/biom9120878 Authors: Polakit Teekakirikul Wenjuan Zhu Helen C. Huang Erik Fung Hypertrophic cardiomyopathy (HCM) is a genetically heterogeneous cardiac muscle disorder with a diverse natural history, characterized by unexplained left ventricular hypertrophy (LVH), with histopathological hallmarks including myocyte enlargement, myocyte disarray and myocardial...
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Biomolecules, Vol. 9, Pages 877: High-Fat Diet Affects Ceramide Content, Disturbs Mitochondrial Redox Balance, and Induces Apoptosis in the Submandibular Glands of Mice Biomolecules doi: 10.3390/biom9120877 Authors: Anna Zalewska Mateusz Maciejczyk Julita Szulimowska Monika Imierska Agnieszka Błachnio-Zabielska This is the first study to investigate the relationship between ceramides, the mitochondrial respiratory system, oxidative stress, inflammation, and apoptosis in the...
Sun Dec 15, 2019 02:00
Biomolecules, Vol. 9, Pages 876: Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPase Biomolecules doi: 10.3390/biom9120876 Authors: Mike Blueggel Johannes van den Boom Hemmo Meyer Peter Bayer Christine Beuck AAA+ ATPase p97/valosin-containing protein (VCP)/Cdc48 is a key player in various cellular stress responses in which it unfolds ubiquitinated proteins to facilitate their degradation by the proteasome....
Sat Dec 14, 2019 02:00
Biomolecules, Vol. 9, Pages 875: The IκB Kinase Inhibitor ACHP Targets the STAT3 Signaling Pathway in Human Non-Small Cell Lung Carcinoma Cells Biomolecules doi: 10.3390/biom9120875 Authors: Jong Hyun Lee Chakrabhavi Dhananjaya Mohan Salundi Basappa Shobith Rangappa Arunachalam Chinnathambi Tahani Awad Alahmadi Sulaiman Ali Alharbi Alan Prem Kumar Gautam Sethi Kwang Seok Ahn Kanchugarakoppal S Rangappa STAT3 is an oncogenic transcription factor that regulates...
Fri Dec 13, 2019 02:00
Biomolecules, Vol. 9, Pages 873: Retinoic Acid Signaling Is Associated with Cell Proliferation, Muscle Cell Dedifferentiation, and Overall Rudiment Size during Intestinal Regeneration in the Sea Cucumber, Holothuria glaberrima Biomolecules doi: 10.3390/biom9120873 Authors: Jorge Viera-Vera José E. García-Arrarás Almost every organism has the ability of repairing damaged tissues or replacing lost and worn out body parts, nevertheless the degree of the response substantially differs...
Fri Dec 13, 2019 02:00
Biomolecules, Vol. 9, Pages 874: Expression of a Chromoplast-Specific Lycopene β-Cyclase Gene (CYC-B) Is Implicated in Carotenoid Accumulation and Coloration in the Loquat Biomolecules doi: 10.3390/biom9120874 Authors: Min Hong Zhuo-Heng Chi Yong-Qing Wang Yue-Ming Tang Qun-Xian Deng Ming-Yang He Ri-Kui Wang Yi-Zhong He Carotenoids are the principal pigments in the loquat. Although the metabolic pathway of plant carotenoids has been extensively investigated, few...
Fri Dec 13, 2019 02:00
Biomolecules, Vol. 9, Pages 871: Lagerstroemia speciosa (L.) Pers Leaf Extract Attenuates Lung Tumorigenesis via Alleviating Oxidative Stress, Inflammation and Apoptosis Biomolecules doi: 10.3390/biom9120871 Authors: Mousa El-Sammad Abdel-Halim Anwar Khalil Nawwar Hashim Elsayed Hassan One of the major etiological factors that account for lung cancer is tobacco use. Benzo(a)pyrene [B(a)P], one of the main constituents of tobacco smoke, has a key role...
Thu Dec 12, 2019 02:00
Biomolecules, Vol. 9, Pages 872: RSM–GA Based Optimization of Bacterial PHA Production and In Silico Modulation of Citrate Synthase for Enhancing PHA Production Biomolecules doi: 10.3390/biom9120872 Authors: Rao Haque El-Enshasy Singh Mishra The inexhaustible nature and biodegradability of bioplastics like polyhydroxyalkanoates (PHAs) make them suitable assets to replace synthetic plastics. The eventual fate of these eco-friendly and non-toxic bioplastics relies upon...
Thu Dec 12, 2019 02:00
Biomolecules, Vol. 9, Pages 870: Biological Evaluation, Molecular Docking, and SAR Studies of Novel 2-(2,4-Dihydroxyphenyl)-1H- Benzimidazole Analogues Biomolecules doi: 10.3390/biom9120870 Authors: Matysiak Skrzypek Karpińska Czarnecka Szymański Bajda Niewiadomy In the present study, new 4-(1H-benzimidazol-2-yl)-benzene-1,3-diols, modified in both rings, have been synthesized and their efficacies as acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE)...
Thu Dec 12, 2019 02:00
Biomolecules, Vol. 9, Pages 869: The Integrity of α-β-α Sandwich Conformation Is Essential for a Novel Adjuvant TFPR1 to Maintain Its Adjuvanticity Biomolecules doi: 10.3390/biom9120869 Authors: Li Ning Wang Zhu Guo Li Zhou Kou TFPR1 is a novel peptide vaccine adjuvant we recently discovered. To define the structural basis and optimize its application as an adjuvant, we designed three different truncated fragments that have removed dominant B epitopes on...
Thu Dec 12, 2019 02:00
Biomolecules, Vol. 9, Pages 868: Generation of Lamprey Monoclonal Antibodies (Lampribodies) Using the Phage Display System Biomolecules doi: 10.3390/biom9120868 Authors: Hassan Hansen Herrin Amemiya The variable lymphocyte receptors (VLRs) consist of leucine rich repeats (LRRs) and comprise the humoral antibodies produced by lampreys and hagfishes. The diversity of the molecules is generated by stepwise genomic rearrangements of LRR cassettes dispersed throughout the VLRB...
Thu Dec 12, 2019 02:00
Biomolecules, Vol. 9, Pages 867: The Interplay between Retinal Pathways of Cholesterol Output and Its Effects on Mouse Retina Biomolecules doi: 10.3390/biom9120867 Authors: Alexey M. Petrov Artem A. Astafev Natalia Mast Aicha Saadane Nicole El-Darzi Irina A. Pikuleva In mammalian retina, cholesterol excess is mainly metabolized to oxysterols by cytochromes P450 27A1 (CYP27A1) and 46A1 (CYP46A1) or removed on lipoprotein particles containing apolipoprotein E (APOE). In...
Thu Dec 12, 2019 02:00
Biomolecules, Vol. 9, Pages 865: Long-Lasting Effects of GSPE on Ileal GLP-1R Gene Expression Are Associated with a Hypomethylation of the GLP-1R Promoter in Female Wistar Rats Biomolecules doi: 10.3390/biom9120865 Authors: Iris Ginés Katherine Gil-Cardoso Claudio D’Addario Anastasia Falconi Fabio Bellia M Teresa Blay Ximena Terra Anna Ardévol Montserrat Pinent Raúl Beltrán-Debón Flavonoids have been shown to modulate GLP-1 in obesity. GLP-1 induces some of...
Thu Dec 12, 2019 02:00
Biomolecules, Vol. 9, Pages 864: Critical Factors in Human Antizymes that Determine the Differential Binding, Inhibition, and Degradation of Human Ornithine Decarboxylase Biomolecules doi: 10.3390/biom9120864 Authors: Ju-Yi Hsieh Yen-Chin Liu I-Ting Cheng Chu-Ju Lee Yu-Hsuan Wang Yi-Shiuan Fang Yi-Liang Liu Guang-Yaw Liu Hui-Chih Hung Antizyme (AZ) is a protein that negatively regulates ornithine decarboxylase (ODC). AZ achieves this inhibition by binding to ODC...
Thu Dec 12, 2019 02:00
Biomolecules, Vol. 9, Pages 866: Model of Early Stage Intermediate in Respect to Its Final Structure
Biomolecules, Vol. 9, Pages 866: Model of Early Stage Intermediate in Respect to Its Final Structure Biomolecules doi: 10.3390/biom9120866 Authors: Piotr Fabian Katarzyna Stapor Irena Roterman The model, describing a method of determining the structure of an early intermediate in the process of protein folding to analyze nonredundant PDB protein bases, allows determining the relationship between the sequence of tetrapeptides and their structural forms expressed by structural codes....
Thu Dec 12, 2019 02:00
Biosensors, Vol. 9, Pages 143: A Critical Comparison between Flow-through and Lateral Flow Immunoassay Formats for Visual and Smartphone-Based Multiplex Allergen Detection Biosensors doi: 10.3390/bios9040143 Authors: Ross Salentijn Nielen (1) Background: The lack of globally standardized allergen labeling legislation necessitates consumer-focused multiplexed testing devices. These should be easy to operate, fast, sensitive and robust. (2) Methods: Herein, we describe the development...
Thu Dec 12, 2019 02:00
Brain Sciences, Vol. 9, Pages 378: Reduced Apoptotic Injury by Phenothiazine in Ischemic Stroke through the NOX-Akt/PKC Pathway Brain Sciences doi: 10.3390/brainsci9120378 Authors: Tong Elkin Peng Shen Li Guan Ji Wei Geng Ding Phenothiazine treatment has been shown to reduce post-stroke ischemic injury, though the underlying mechanism remains unclear. This study sought to confirm the neuroprotective effects of phenothiazines and to explore the role...
Sun Dec 15, 2019 02:00
Brain Sciences, Vol. 9, Pages 377: Characteristics of the Uncinate Fasciculus and Cingulum in Patients with Mild Cognitive Impairment: Diffusion Tensor Tractography Study Brain Sciences doi: 10.3390/brainsci9120377 Authors: Chan-Hyuk Park Su-Hong Kim Han-Young Jung Many studies have examined the relationship between cognition, and the cingulum and uncinate fasciculus (UF). In this study, diffusion tensor tractography (DTT) was used to investigate the correlation between fractional-anisotropy...
Sat Dec 14, 2019 02:00
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