IJERPH, Vol. 17, Pages 842: Keeping People with Dementia or Mild Cognitive Impairment in Employment: A Literature Review on Its Determinants International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030842 Authors: Silvaggi Leonardi Tiraboschi Muscio Toppo Raggi Background: Approximately 10–20% of people with early onset dementias (EOD) or mild cognitive impairment (MCI) are aged under 65 and, due to extended working life and...
Wed Jan 29, 2020 02:00
IJERPH, Vol. 17, Pages 832: Differences among Saudi and Expatriate Students: Body Composition Indices, Sitting Time Associated with Media Use and Physical Activity Pattern International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030832 Authors: Alghadir Iqbal Gabr Background: Being overweight at a young age is a predictor of developing obesity and related complications later in adulthood, posing a high risk to public health. Various ethnic subgroups...
Wed Jan 29, 2020 02:00
IJERPH, Vol. 17, Pages 835: Impact of Nurse-Patient Relationship on Quality of Care and Patient Autonomy in Decision-Making International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030835 Authors: Jesús Molina-Mula Julia Gallo-Estrada Background: The patient is observed to acquire a passive role and the nurse an expert role with a maternalistic attitude. This relationship among others determines the capacity for autonomy in the decision making of patients....
Wed Jan 29, 2020 02:00
IJERPH, Vol. 17, Pages 833: “Our Tradition Our Enemy”: A Qualitative Study of Barriers to Women’s HIV Care in Jimma, Southwest Ethiopia International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030833 Authors: Gesesew Lyon Ward Woldemichael Mwanri Evidence exists that suggests that women are vulnerable to negative HIV treatment outcomes worldwide. This study explored barriers to treatment outcomes of women in Jimma, Southwest Ethiopia. We...
Wed Jan 29, 2020 02:00
IJERPH, Vol. 17, Pages 837: Sport Education and Sportsmanship Orientations: An Intervention in High School Students International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030837 Authors: Burgueño Medina-Casaubón One of the main goals for physical education is to develop the students’ moral and ethical domain, where sportsmanship promotion is considered a key curricular component to tackle the achievement of this goal. This research aims...
Wed Jan 29, 2020 02:00
IJERPH, Vol. 17, Pages 834: Association between Sudden Sensorineural Hearing Loss and Preexisting Thyroid Diseases: A Nationwide Case-Control Study in Taiwan International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030834 Authors: Tsai Chang Hsu Yang Liu Tsai Chang Lee Huang Lin Luan Background: Little evidence is available about the risk of sudden sensorineural hearing loss (SSNHL) in patients with thyroid diseases....
Wed Jan 29, 2020 02:00
IJERPH, Vol. 17, Pages 840: Supervision Incivility and Employee Psychological Safety in the Workplace International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030840 Authors: Liu Yu Chen He Much of the supervision incivility research has focused on the supervisor-subordinate dyad when examining the effects of supervision incivility on employee outcomes. Our study examines a trickle-down effect of supervision incivility across three hierarchical...
Wed Jan 29, 2020 02:00
IJERPH, Vol. 17, Pages 844: Problematic Smartphone Use and Mental Health in Chinese Adults: A Population-Based Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030844 Authors: Ningyuan Guo Tzu Tsun Luk Sai Yin Ho Jung Jae Lee Chen Shen John Oliffe Sophia Siu-Chee Chan Tai Hing Lam Man Ping Wang Problematic smartphone use (PSU) has been associated with anxiety and depression, but few explored its mental well-being correlates...
Wed Jan 29, 2020 02:00
IJERPH, Vol. 17, Pages 845: Pollution Characteristics of Microplastics in Soils in Southeastern Suburbs of Baoding City, China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030845 Authors: Chuan Du Handong Liang Zhanping Li Jie Gong Microplastics (MPs) are emerging pollutants that exist in different environmental media. Because of their wide range and large potential environmental hazards, they have attracted widespread attention in recent...
Wed Jan 29, 2020 02:00
IJERPH, Vol. 17, Pages 830: Global Research Trends and Hotspots on Submarine Groundwater Discharge (SGD): A Bibliometric Analysis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030830 Authors: Qian Ma Yan Zhang Submarine groundwater discharge (SGD), a major component of the hydrological cycle, has significant impacts on the sustainable development of the marine environment. This study aimed to examine the literature characteristics and research...
Wed Jan 29, 2020 02:00
IJERPH, Vol. 17, Pages 829: Some Interval-Valued Intuitionistic Fuzzy Dombi Heronian Mean Operators and their Application for Evaluating the Ecological Value of Forest Ecological Tourism Demonstration Areas International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030829 Authors: Wu Wei Wu Wei With China’s sustained economic development and constant increase in national income, Chinese nationals’ tourism consumption rate increases....
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 894: Molecular Imaging of Pulmonary Inflammation and Infection International Journal of Molecular Sciences doi: 10.3390/ijms21030894 Authors: Giraudo Evangelista Fraia Lupi Quaia Cecchin Casali Infectious and inflammatory pulmonary diseases are a leading cause of morbidity and mortality worldwide. Although infrequently used in this setting, molecular imaging may significantly contribute to their diagnosis using techniques like single photon...
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IJMS, Vol. 21, Pages 889: Comparative Efficacy and Safety of Dupilumab and Benralizumab in Patients with Inadequately Controlled Asthma: A Systematic Review International Journal of Molecular Sciences doi: 10.3390/ijms21030889 Authors: Ando Tanaka Sagara No head-to-head trials have compared the efficacy and safety between the licensed dosage and administration dosage of dupilumab and benralizumab for inadequately controlled asthma. We conducted an indirect treatment comparison...
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IJMS, Vol. 21, Pages 881: High-Mobility Group Box 1 Protein Signaling in Painful Diabetic Neuropathy
IJMS, Vol. 21, Pages 881: High-Mobility Group Box 1 Protein Signaling in Painful Diabetic Neuropathy International Journal of Molecular Sciences doi: 10.3390/ijms21030881 Authors: Thakur Sadanandan Chattopadhyay Diabetes is a global epidemic and more than 50% diabetic patients are also diagnosed with neuropathy, which greatly affects the quality of life of the patients. Available treatments are not always successful due to the limited efficacy and complications, such as addiction...
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IJMS, Vol. 21, Pages 891: The Pathogenic Role of Very Low Density Lipoprotein on Atrial Remodeling in the Metabolic Syndrome International Journal of Molecular Sciences doi: 10.3390/ijms21030891 Authors: Lee Lin Atrial fibrillation (AF) is the most common persistent arrhythmia, and can lead to systemic thromboembolism and heart failure. Aging and metabolic syndrome (MetS) are major risks for AF. One of the most important manifestations of MetS is dyslipidemia, but its correlation...
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IJMS, Vol. 21, Pages 892: Proteomic and Genomic Changes in Tau Protein, which are Associated with Alzheimer’s Disease After Ischemia-Reperfusion Brain Injury International Journal of Molecular Sciences doi: 10.3390/ijms21030892 Authors: Ułamek-Kozioł Czuczwar Januszewski Pluta Recent evidence suggests that transient ischemia of the brain with reperfusion in humans and animals is associated with the neuronal accumulation of neurotoxic molecules associated with Alzheimer’s...
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IJMS, Vol. 21, Pages 893: Elucidating Binding Sites and Affinities of ERα Agonists and Antagonists to Human Alpha-Fetoprotein by In Silico Modeling and Point Mutagenesis International Journal of Molecular Sciences doi: 10.3390/ijms21030893 Authors: Moldogazieva Ostroverkhova Kuzmich Kadochnikov Terentiev Porozov Alpha-fetoprotein (AFP) is a major embryo- and tumor-associated protein capable of binding and transporting a variety of hydrophobic ligands, including estrogens....
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IJMS, Vol. 21, Pages 895: Human Tyrosinase: Temperature-Dependent Kinetics of Oxidase Activity International Journal of Molecular Sciences doi: 10.3390/ijms21030895 Authors: II Kassouf Dolinska Anderson Sergeev Human tyrosinase (Tyr) is involved in pigment biosynthesis, where mutations in its corresponding gene TYR have been linked to oculocutaneous albinism 1, an autosomal recessive disorder. Although the enzymatic capabilities of Tyr have been well-characterized, the...
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IJMS, Vol. 21, Pages 897: Hepatitis C Virus p7 Induces Membrane Permeabilization by Interacting with Phosphatidylserine International Journal of Molecular Sciences doi: 10.3390/ijms21030897 Authors: Lee Lee You Kim Yoo Hepatitis C virus (HCV) p7 is known to be a nonselective cation channel for HCV maturation. Because the interaction of HCV proteins with host lipids in the endoplasmic reticulum membrane is crucial for the budding process, the identification of p7–lipid...
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IJMS, Vol. 21, Pages 898: Differential Effects of 2-Hydroxypropyl-Cyclodextrins on Lipid Accumulation in Npc1-Null Cells International Journal of Molecular Sciences doi: 10.3390/ijms21030898 Authors: Hoque Kondo Sakata Yamada Fukaura Higashi Motoyama Arima Higaki Hayashi Komiya Ishitsuka Irie Niemann–Pick disease type C (NPC) is an autosomal recessive disorder characterized by abnormal accumulation of free cholesterol and sphingolipids...
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IJMS, Vol. 21, Pages 890: Estradiol-17β-Induced Changes in the Porcine Endometrial Transcriptome In Vivo International Journal of Molecular Sciences doi: 10.3390/ijms21030890 Authors: Kaczynski Bauersachs Baryla Goryszewska Muszak Grzegorzewski Waclawik Estradiol-17β (E2) is a key hormone regulating reproductive functions in females. In pigs, E2, as the main conceptus signal, initiates processes resulting in prolonged corpus luteum function, embryo development,...
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IJMS, Vol. 21, Pages 887: Lipidated Analogs of the LL-37-Derived Peptide Fragment KR12—Structural Analysis, Surface-Active Properties and Antimicrobial Activity International Journal of Molecular Sciences doi: 10.3390/ijms21030887 Authors: Kamysz Sikorska Jaśkiewicz Bauer Neubauer Bartoszewska Barańska-Rybak Kamysz An increasing number of multidrug-resistant pathogens is a serious problem of modern medicine and new antibiotics are highly demanded. In this...
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IJMS, Vol. 21, Pages 884: Genetic Dissection of Alzheimer’s Disease Using Drosophila Models International Journal of Molecular Sciences doi: 10.3390/ijms21030884 Authors: Jeon Lee Choi Won Cho Alzheimer’s disease (AD), a main cause of dementia, is the most common neurodegenerative disease that is related to abnormal accumulation of the amyloid β (Aβ) protein. Despite decades of intensive research, the mechanisms underlying AD remain elusive,...
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IJMS, Vol. 21, Pages 886: Differential Effects of Dietary Supplementation of Krill Meal, Soybean Meal, Butyrate, and Bactocell® on the Gene Expression of Atlantic Salmon Head Kidney International Journal of Molecular Sciences doi: 10.3390/ijms21030886 Authors: Jalili Gerdol Greco Pallavicini Buonocore Scapigliati Picchietti Esteban Rye Bones The head kidney is a key organ that plays a fundamental role in the regulation of the fish immune response...
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IJMS, Vol. 21, Pages 885: IBTK Haploinsufficiency Affects the Tumor Microenvironment of Myc-Driven Lymphoma in E-myc Mice International Journal of Molecular Sciences doi: 10.3390/ijms21030885 Authors: Vecchio Fiume Mignogna Iaccino Mimmi Maisano Trapasso Quinto The tumor microenvironment is a dynamic and interactive supporting network of various components, including blood vessels, cytokines, chemokines, and immune cells, which sustain the tumor cell’s...
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IJMS, Vol. 21, Pages 888: Integrin Signaling in Glioma Pathogenesis: From Biology to Therapy International Journal of Molecular Sciences doi: 10.3390/ijms21030888 Authors: Ellert-Miklaszewska Poleszak Pasierbinska Kaminska Integrins are a large family of transmembrane adhesion receptors, which play a key role in interactions of a cell with the surrounding stroma. Integrins are comprised of non-covalently linked α and β chains, which form heterodimeric...
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IJMS, Vol. 21, Pages 883: Rapid and Effective Generation of Nanobody Based CARs using PCR and Gibson Assembly International Journal of Molecular Sciences doi: 10.3390/ijms21030883 Authors: De Munter Van Parys Bral Ingels Goetgeluk Bonte Pille Billiet Weening Verhee Van der Heyden Taghon Leclercq Kerre Tavernier Vandekerckhove Recent approval of chimeric antigen receptor (CAR) T cell therapy by the European Medicines Agency...
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IJMS, Vol. 21, Pages 882: Nitric Oxide and Hydrogen Peroxide Signaling in Extractive Shiraia Fermentation by Triton X-100 for Hypocrellin A Production International Journal of Molecular Sciences doi: 10.3390/ijms21030882 Authors: Li Wang Ma Wang Zheng Shiraia mycelial culture is a promising biotechnological alternative for the production of hypocrellin A (HA), a new photosensitizer for anticancer photodynamic therapy (PDT). The extractive fermentation of intracellular...
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IJMS, Vol. 21, Pages 880: High Diagnostic Accuracy of RT-QuIC Assay in a Prospective Study of Patients with Suspected sCJD International Journal of Molecular Sciences doi: 10.3390/ijms21030880 Authors: Fiorini Iselle Perra Bongianni Capaldi Sacchetto Ferrari Mombello Vascellari Testi Monaco Zanusso The early and accurate in vivo diagnosis of sporadic Creutzfeldt–Jakob disease (sCJD) is essential in order to differentiate CJD from...
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IJMS, Vol. 21, Pages 879: The Role of Immune Checkpoint Blockade in Uveal Melanoma International Journal of Molecular Sciences doi: 10.3390/ijms21030879 Authors: Wessely Steeb Erdmann Heinzerling Vera Schlaak Berking Heppt Uveal melanoma (UM) represents the most common intraocular malignancy in adults and accounts for about 5% of all melanomas. Primary disease can be effectively controlled by several local therapy options, but UM has a high potential for...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 878: The miRNAs Role in Melanoma and in Its Resistance to Therapy International Journal of Molecular Sciences doi: 10.3390/ijms21030878 Authors: Varrone Caputo Melanoma is the less common but the most malignant skin cancer. Since the survival rate of melanoma metastasis is about 10–15%, many different studies have been carried out in order to find a more effective treatment. Although the development of target-based therapies and immunotherapeutic strategies...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 876: (+)-Usnic Acid Induces ROS-dependent Apoptosis via Inhibition of Mitochondria Respiratory Chain Complexes and Nrf2 Expression in Lung Squamous Cell Carcinoma International Journal of Molecular Sciences doi: 10.3390/ijms21030876 Authors: Qi Lu Huang Zhang Song Liu Lung squamous cell carcinoma (LUSC) has a poor prognosis, in part due to poor therapeutic response and limited therapeutic alternatives. Lichens are symbiotic organisms, producing...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 867: The Peroxisomal PTS1-Import Defect of PEX1- Deficient Cells Is Independent of Pexophagy in Saccharomyces cerevisiae International Journal of Molecular Sciences doi: 10.3390/ijms21030867 Authors: Mastalski Brinkmeier Platta The important physiologic role of peroxisomes is shown by the occurrence of peroxisomal biogenesis disorders (PBDs) in humans. This spectrum of autosomal recessive metabolic disorders is characterized by defective peroxisome assembly...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 868: GM1 Ganglioside Is A Key Factor in Maintaining the Mammalian Neuronal Functions Avoiding Neurodegeneration International Journal of Molecular Sciences doi: 10.3390/ijms21030868 Authors: Chiricozzi Lunghi Biase Fazzari Sonnino Mauri Many species of ganglioside GM1, differing for the sialic acid and ceramide content, havebeen characterized and their physico‐chemical properties have been studied in detail since 1963.Scientists were immediately...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 869: Cationic Polymer Nanoparticles-Mediated Delivery of miR-124 Impairs Tumorigenicity of Prostate Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms21030869 Authors: Conte Valentino Di Cristo Peluso Cerruti Di Salle Calarco MicroRNAs (miRNAs) play a pivotal role in regulating the expression of genes involved in tumor development, invasion, and metastasis. In particular, microRNA-124 (miR-124) modulates the expression...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 870: Interplay between BRCA1 and GADD45A and Its Potential for Nucleotide Excision Repair in Breast Cancer Pathogenesis International Journal of Molecular Sciences doi: 10.3390/ijms21030870 Authors: Pietrasik Zajac Morawiec Soszynski Fila Blasiak A fraction of breast cancer cases are associated with mutations in the BRCA1 (BRCA1 DNA repair associated, breast cancer type 1 susceptibility protein) gene, whose mutated product may disrupt the repair...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 875: Poly(ADP-Ribose) Polymerase-3 Regulates Regeneration in Planarians International Journal of Molecular Sciences doi: 10.3390/ijms21030875 Authors: Barghouth Karabinis Venegas Oviedo Protein ADP-ribosylation is a reversible post-translational modification (PTM) process that plays fundamental roles in cell signaling. The covalent attachment of ADP ribose polymers is executed by PAR polymerases (PARP) and it is essential for chromatin organization,...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 871: The Biofunctional Effects of Mesima as a Radiosensitizer for Hepatocellular Carcinoma International Journal of Molecular Sciences doi: 10.3390/ijms21030871 Authors: Jeong Oh Yoo Lim Kim The tropical basidiomycete fungus Phellinus linteus (Mesima) exhibits anti-tumor, anti-angiogenic, and immunomodulatory properties in various cancers including prostate, colon, and lung cancer along with melanoma by, for example, inducing apoptosis or cell cycle...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 872: Roles of Brassinosteroids in Plant Reproduction International Journal of Molecular Sciences doi: 10.3390/ijms21030872 Authors: Li He Brassinosteroids (BRs) are a group of steroid hormones, essentially important for plant development and growth. BR signaling functions to promote cell expansion and cell division, and plays a role in etiolation and reproduction. As the phytohormone originally identified in the pollen grains of Brassica napus, BR promotes the...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 873: Optimization of Chitosan–Alginate Microparticles for Delivery of Mangostins to the Colon Area Using Box–Behnken Experimental Design International Journal of Molecular Sciences doi: 10.3390/ijms21030873 Authors: Mulia Singarimbun Krisanti Chitosan-alginate microparticles loaded with hydrophobic mangostins present in the mangosteen rind extract have been formulated and optimized for colon-targeted bioactive drug delivery systems. The chitosan–mangostin...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 874: Degradation of Human Serum Albumin by Infrared Free Electron Laser Enhanced by Inclusion of a Salen-Type Schiff Base Zn (II) Complex International Journal of Molecular Sciences doi: 10.3390/ijms21030874 Authors: Onami Kawasaki Aizawa Haraguchi Akitsu Tsukiyama Palafox A salen-type Schiff base Zn(II) complex included in human serum albumin (HSA) protein was examined by UV-Vis, circular dichroism (CD), and fluorescence (PL) spectra. The...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 877: miR-20b and miR-451a Are Involved in Gastric Carcinogenesis through the PI3K/AKT/mTOR Signaling Pathway: Data from Gastric Cancer Patients, Cell Lines and Ins-Gas Mouse Model International Journal of Molecular Sciences doi: 10.3390/ijms21030877 Authors: Streleckiene Inciuraite Juzenas Salteniene Steponaitiene Gyvyte Kiudelis Leja Ruzgys Satkauskas Kupcinskiene Franke Thon Link Kupcinskas Skieceviciene ...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 863: Genome-Wide Characterization and Analysis of CIPK Gene Family in Two Cultivated Allopolyploid Cotton Species: Sequence Variation, Association with Seed Oil Content, and the Role of GhCIPK6 International Journal of Molecular Sciences doi: 10.3390/ijms21030863 Authors: Cui Su Wang Jia Wu Pei Zhang Yu Calcineurin B-like protein-interacting protein kinases (CIPKs), as key regulators, play an important role in plant growth and development...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 864: Whey-Derived Peptides Interactions with ACE by Molecular Docking as a Potential Predictive Tool of Natural ACE Inhibitors International Journal of Molecular Sciences doi: 10.3390/ijms21030864 Authors: Chamata Watson Jauregi Several milk/whey derived peptides possess high in vitro angiotensin I-converting enzyme (ACE) inhibitory activity. However, in some cases, poor correlation between the in vitro ACE inhibitory activity and the in vivo antihypertensive...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 865: Impact of Janus Kinase Inhibition with Tofacitinib on Fundamental Processes of Bone Healing International Journal of Molecular Sciences doi: 10.3390/ijms21030865 Authors: Gaber Brinkman Pienczikowski Diesing Damerau Pfeiffenberger Lang Ohrndorf Burmester Buttgereit Hoff Both inflammatory diseases like rheumatoid arthritis (RA) and anti-inflammatory treatment of RA with glucocorticoids (GCs) or non-steroidal anti-inflammatory...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 866: Reduced miR-26b Expression in Megakaryocytes and Platelets Contributes to Elevated Level of Platelet Activation Status in Sepsis International Journal of Molecular Sciences doi: 10.3390/ijms21030866 Authors: Bernadett Szilágyi Zsolt Fejes Szilárd Póliska Marianna Pócsi Zsolt Czimmerer Andreas Patsalos Ferenc Fenyvesi Ágnes Rusznyák György Nagy György Kerekes Mariann Berhés Ildikó Szűcs Satya P. Kunapuli János Kappelmayer Béla...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 862: Azalomycin F5a Eradicates Staphylococcus aureus Biofilm by Rapidly Penetrating and Subsequently Inducing Cell Lysis International Journal of Molecular Sciences doi: 10.3390/ijms21030862 Authors: Ganjun Yuan Pingyi Li Xuejie Xu Peibo Li Qiwang Zhong Su He Houqin Yi Wenfang Yi Yingying Guan Zezhang Tom Wen Antimicrobial resistance has emerged as a serious threat to public health. Bacterial biofilm, as a natural lifestyle, is a major...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 857: Protective Effects of Zerumbone on Colonic Tumorigenesis in Enterotoxigenic Bacteroides fragilis (ETBF)-Colonized AOM/DSS BALB/c Mice International Journal of Molecular Sciences doi: 10.3390/ijms21030857 Authors: Hwang Jo Hong Park Lee Rhee Chronic inflammation has been linked to colitis-associated colorectal cancer in humans. The human symbiont enterotoxigenic Bacteroides fragilis (ETBF), a pro-carcinogenic bacterium, has the potential...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 858: Influence of Germline Genetics on Tacrolimus Pharmacokinetics and Pharmacodynamics in Allogeneic Hematopoietic Stem Cell Transplant Patients International Journal of Molecular Sciences doi: 10.3390/ijms21030858 Authors: Zhu Patel Miller Torrice Aggarwal Alexander Armistead Coghill Grgic Jamieson Ptachcinski Riches Serody Schmitz Shaw Shea Suzuki Vincent Wood Rao Wiltshire Crona ...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 860: Molecular Interactions of Carbapenem Antibiotics with the Multidrug Efflux Transporter AcrB of Escherichia coli International Journal of Molecular Sciences doi: 10.3390/ijms21030860 Authors: Atzori Malloci Cardamone Bosin Vargiu Ruggerone The drug/proton antiporter AcrB, engine of the major efflux pump AcrAB(Z)-TolC of Escherichia coli and other bacteria, is characterized by its impressive ability to transport chemically diverse compounds,...
Wed Jan 29, 2020 02:00
IJMS, Vol. 21, Pages 859: The Roles of Lipoprotein in Psoriasis International Journal of Molecular Sciences doi: 10.3390/ijms21030859 Authors: Shih Chen Chu Wang Huang Lee The association between psoriasis and cardiovascular disease risk has been supported by recent epidemiological data. Patients with psoriasis have an increased adjusted relative risk for myocardial infarction. As such, the cardiovascular risk conferred by severe psoriasis may be comparable to what...
Wed Jan 29, 2020 02:00
JCM, Vol. 9, Pages 375: C3d-Positive Preformed DSAs Tend to Persist and Result in a Higher Risk of AMR after Kidney Transplants Journal of Clinical Medicine doi: 10.3390/jcm9020375 Authors: Choi Lee Park Kim Jang Huh Kang C3d-binding assays have been introduced as methods for the prediction of the presence of complement-binding functional antibodies; however, the prognostic value of C3d-positive preformed donor-specific antibodies (pDSAs) has not been fully evaluated....
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JCM, Vol. 9, Pages 373: Levosimendan Improves Oxidative Balance in Cardiogenic Shock/Low Cardiac Output Patients Journal of Clinical Medicine doi: 10.3390/jcm9020373 Authors: Grossini Farruggio Pierelli Bolzani Rossi Pollesello Monaco The beneficial effects exerted by levosimendan against cardiac failure could be related to the modulation of oxidative balance. We aimed to examine the effects of levosimendan in patients with cardiogenic shock or low cardiac output...
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JCM, Vol. 9, Pages 372: Loss-of-Function Variants in Cytoskeletal Genes Are Associated with Early-Onset Atrial Fibrillation Journal of Clinical Medicine doi: 10.3390/jcm9020372 Authors: Vad Paludan-Müller Ahlberg Kalstø Ghouse Andreasen Haunsø Tveit Sajadieh Christophersen Svendsen Olesen Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it is associated with an increased risk of heart failure, stroke, dementia, and death....
Wed Jan 29, 2020 02:00
JCM, Vol. 9, Pages 370: Analysis of De Novo Mutations in Sporadic Cardiomyopathies Emphasizes Their Clinical Relevance and Points to Novel Candidate Genes Journal of Clinical Medicine doi: 10.3390/jcm9020370 Authors: Franaszczyk Truszkowska Chmielewski Rydzanicz Kosinska Rywik Biernacka Spiewak Kostrzewa Stepien-Wojno Stawinski Bilinska Krajewski Zielinski Lutynska Bilinska Ploski The vast majority of cardiomyopathies have...
Wed Jan 29, 2020 02:00
JCM, Vol. 9, Pages 371: Percutaneous Endoscopic Cervical Discectomy Versus Anterior Cervical Discectomy and Fusion: A Comparative Cohort Study with a Five-Year Follow-Up Journal of Clinical Medicine doi: 10.3390/jcm9020371 Authors: Ahn Keum Shin Percutaneous endoscopic cervical discectomy (PECD) is an effective minimally invasive surgery for soft cervical disc herniation in properly selected cases. The current gold standard is anterior cervical discectomy and fusion (ACDF)....
Wed Jan 29, 2020 02:00
JCM, Vol. 9, Pages 369: Metagenomic Analysis of Duodenal Microbiota Reveals a Potential Biomarker of Dysbiosis in the Course of Obesity and Type 2 Diabetes: A Pilot Study Journal of Clinical Medicine doi: 10.3390/jcm9020369 Authors: Sroka-Oleksiak Młodzińska Bulanda Salamon Major Stanek Gosiewski Numerous scientific studies confirm that, apart from environmental and genetic factors, a significant role is played by gastrointestinal microbiota in the aetiology...
Wed Jan 29, 2020 02:00
JCM, Vol. 9, Pages 368: Comparison of the Genomic Profile of Cancer Stem Cells and Their Non-Stem Counterpart: The Case of Ovarian Cancer Journal of Clinical Medicine doi: 10.3390/jcm9020368 Authors: Mazzoldi Pastò Pilotto Minuzzo Piga Palumbo Carella Frezzini Nicoletto Amadori Indraccolo The classical cancer stem cell (CSC) model places CSCs at the apex of a hierarchical scale, suggesting different genetic alterations in non-CSCs compared to...
Wed Jan 29, 2020 02:00
JCM, Vol. 9, Pages 366: Body-Mass-Index Associated Differences in Ortho‐ and Retronasal Olfactory Function and the Individual Significance of Olfaction in Health and Disease Journal of Clinical Medicine doi: 10.3390/jcm9020366 Authors: Besser Erlacher Aydinkoc-Tuzcu Liu Pablik Niebauer Koenighofer Renner Mueller Odor (including flavor) perception plays a major role in dietary behavior. Orthonasal olfactory function (OOF) has been shown to decrease in...
Wed Jan 29, 2020 02:00
JCM, Vol. 9, Pages 367: Using Whole Breast Ultrasound Tomography to Improve Breast Cancer Risk Assessment: A Novel Risk Factor Based on the Quantitative Tissue Property of Sound Speed Journal of Clinical Medicine doi: 10.3390/jcm9020367 Authors: Duric Sak Fan Pfeiffer Littrup Simon Gorski Ali Purrington Brem Sherman Gierach Mammographic percent density (MPD) is an independent risk factor for developing breast cancer, but its inclusion in clinical...
Wed Jan 29, 2020 02:00
JCM, Vol. 9, Pages 365: Shoulder Muscle Strength and Neuromuscular Activation 2 Years after Reverse Shoulder Prosthesis—An Experimental Case Control Study Journal of Clinical Medicine doi: 10.3390/jcm9020365 Authors: Rienmüller Maffiuletti Schwyzer Eggspühler Although reverse shoulder arthroplasty (RSA) has shown successful postoperative outcomes, little is known about compensatory activation patterns of remaining shoulder muscles following RSA. The purpose of this experimental...
Wed Jan 29, 2020 02:00
JCM, Vol. 9, Pages 364: Validation of Deep Learning-Based Artifact Correction on Synthetic FLAIR Images in a Different Scanning Environment Journal of Clinical Medicine doi: 10.3390/jcm9020364 Authors: Ryu Baek Gho Ryu Kim Park Ha Cho Lee We investigated the capability of a trained deep learning (DL) model with a convolutional neural network (CNN) in a different scanning environment in terms of ameliorating the quality of synthetic fluid-attenuated inversion...
Wed Jan 29, 2020 02:00
JFMK, Vol. 5, Pages 9: Massage Therapy Modulates Inflammatory Mediators Following Sprint Exercise in Healthy Male Athletes Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5010009 Authors: White West Caterini Battista Rhind Wells Massage therapy is a common postexercise muscle recovery modality; however, its mechanisms of efficacy are uncertain. We evaluated the effects of massage on systemic inflammatory responses to exercise and postexercise muscle...
Wed Jan 29, 2020 02:00
Medicina, Vol. 56, Pages 57: Overexpression of KLF17 Predicts a Favorable Prognosis in Patients with Oral Squamous Cell Carcinoma: A Retrospective Study Medicina doi: 10.3390/medicina56020057 Authors: Lee Chan Yeh Lee Sung Background and Objectives: Patients with oral squamous cell carcinoma (OSCC), a common malignancy in Asian countries, have a poor prognosis. We investigated the role of Krüppel-like factor 17 (KLF17) and its prognostic significance in OSCC....
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Medicina, Vol. 56, Pages 55: Antibacterial Properties of Nanoparticles in Dental Restorative Materials. A Systematic Review and Meta-Analysis Medicina doi: 10.3390/medicina56020055 Authors: Ferrando-Magraner Bellot-Arcís Paredes-Gallardo Almerich-Silla García-Sanz Fernández-Alonso Montiel-Company Background and Objectives: Nanotechnology has become a significant area of research focused mainly on increasing the antibacterial and mechanical properties of dental...
Wed Jan 29, 2020 02:00
Medicina, Vol. 56, Pages 56: Development of a Knee Joint CT-FEM Model in Load Response of the Stance Phase During Walking Using Muscle Exertion, Motion Analysis, and Ground Reaction Force Data Medicina doi: 10.3390/medicina56020056 Authors: Watanabe Mutsuzaki Fukaya Aoyama Nakajima Sekine Mori Background and objectives: There are no reports on articular stress distribution during walking based on any computed tomography (CT)-finite element model (CT-FEM). This...
Wed Jan 29, 2020 02:00
Metabolites, Vol. 10, Pages 53: Metabolomic Profiling of Wildtype and Transgenic Giardia lamblia Strains by 1H HR-MAS NMR Spectroscopy Metabolites doi: 10.3390/metabo10020053 Authors: Müller Vermathen Leitsch Vermathen Müller Giardia lamblia, a causative agent of persistent diarrhea in humans, domestic animals, and cattle, is usually treated with nitro compounds. Consequently, enzymes involved in anaerobic nitro reduction have been investigated in detail as potential...
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Metabolites, Vol. 10, Pages 51: Toward a Standardized Strategy of Clinical Metabolomics for the Advancement of Precision Medicine Metabolites doi: 10.3390/metabo10020051 Authors: Long Nghi Kang Anh Kim Park Kwon Despite the tremendous success, pitfalls have been observed in every step of a clinical metabolomics workflow, which impedes the internal validity of the study. Furthermore, the demand for logistics, instrumentations, and computational resources for metabolic...
Wed Jan 29, 2020 02:00
Metabolites, Vol. 10, Pages 52: Metabolomics as an Emerging Tool for the Study of Plant–Pathogen Interactions Metabolites doi: 10.3390/metabo10020052 Authors: Castro-Moretti Gentzel Mackey Alonso Plants defend themselves from most microbial attacks via mechanisms including cell wall fortification, production of antimicrobial compounds, and generation of reactive oxygen species. Successful pathogens overcome these host defenses, as well as obtain nutrients from the host....
Wed Jan 29, 2020 02:00
Microorganisms, Vol. 8, Pages 189: Preliminary Evaluation of the Safety and Probiotic Potential of Akkermansia muciniphila DSM 22959 in Comparison with Lactobacillus rhamnosus GG. Microorganisms doi: 10.3390/microorganisms8020189 Authors: Cozzolino Vergalito Tremonte Iorizzo Lombardi Sorrentino Luongo Coppola Marco Succi In this study, for the first time, we examined some of the physico-chemical properties of the cell surface of Akkermansia muciniphila...
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Microorganisms, Vol. 8, Pages 188: Long-Term Mesophilic Anaerobic Co-Digestion of Swine Manure with Corn Stover and Microbial Community Analysis Microorganisms doi: 10.3390/microorganisms8020188 Authors: Wang Lim Duong Zhang Xu Yan Mei Wang Long-term anaerobic co-digestion of swine manure (SM) and corn stover (CS) was conducted using semi-continuously loaded digesters under mesophilic conditions. A preliminary test was first conducted to test the effects...
Wed Jan 29, 2020 02:00
Microorganisms, Vol. 8, Pages 187: Uptake of Inorganic and Organic Nitrogen Sources by Dinophysis acuminata and D. acuta Microorganisms doi: 10.3390/microorganisms8020187 Authors: García-Portela Reguera Gago Gac Rodríguez Dinoflagellate species of Dinophysis are obligate mixotrophs that require light, nutrients, and prey for sustained growth. Information about their nitrogenous nutrient preferences and their uptake kinetics are scarce. This study aimed to determine the...
Wed Jan 29, 2020 02:00
Molbank, Vol. 2020, Article M1113: 1-Phenyl-8-[[4-(pyrrolo[1,2-a]quinoxalin-4-yl)phenyl]methyl]-1,3,8-triazaspiro[4.5]decan-4-one: Synthesis, Crystal Structure and Anti-Leukemic Activity Molbank doi: 10.3390/M1113 Authors: Guillon Savrimoutou Rubio Moreau Pinaud Marchivie Desplat 1-Phenyl-8-[[4-(pyrrolo[1,2-a]quinoxalin-4-yl)phenyl]methyl]-1,3,8-triazaspiro[4.5]decan-4-one has been successfully synthesized via a multi-step pathway starting from 2-nitroaniline....
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 597: A Self-Healing Polymer with Fast Elastic Recovery upon Stretching Molecules doi: 10.3390/molecules25030597 Authors: Pei-Chen Zhao Wen Li Wei Huang Cheng-Hui Li The design of polymers that exhibit both good elasticity and self-healing properties is a highly challenging task. In spite of this, the literature reports highly stretchable self-healing polymers, but most of them exhibit slow elastic recovery behavior, i.e., they can only recover to their...
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Molecules, Vol. 25, Pages 596: Pleiotropic Biological Effects of Dietary Phenolic Compounds and their Metabolites on Energy Metabolism, Inflammation and Aging Molecules doi: 10.3390/molecules25030596 Authors: María del Carmen Villegas-Aguilar Álvaro Fernández-Ochoa María de la Luz Cádiz-Gurrea Sandra Pimentel-Moral Jesús Lozano-Sánchez David Arráez-Román Antonio Segura-Carretero Dietary phenolic compounds are considered as bioactive compounds that have effects in different...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 595: Thymol Chemotype Origanum vulgare L. Essential Oil as a Potential Selective Bio-Based Herbicide on Monocot Plant Species Molecules doi: 10.3390/molecules25030595 Authors: Gruľová Caputo Elshafie Baranová De Martino Sedlák Gogaľová Poráčová Camele De Feo Searching for new bio-based herbicides is crucial for decreasing chemical pollution, protecting the environment, and sustaining biodiversity. Origanum vulgare is considered...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 594: Gut Microbiota and Its Metabolites in Atherosclerosis Development Molecules doi: 10.3390/molecules25030594 Authors: Pieczynska Yang Petrykowski Horbanczuk Atanasov Horbanczuk : Gut microbiota metabolites have a great influence on host digestive function and body health itself. The effects of intestinal microbes on the host metabolism and nutrients absorption are mainly due to regulatory mechanisms related to serotonin, cytokines, and...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 592: Effective Biobased Phosphorus Flame Retardants from Starch-Derived bis-2,5-(Hydroxymethyl)Furan Molecules doi: 10.3390/molecules25030592 Authors: Howell Han A series of biobased phosphorus flame retardants has been prepared by converting starch-derived bis-2,5-(hydroxymethyl)furan to the corresponding diacrylate followed by Michael addition of phosphite to generate derivatives with phosphorus moieties attached via P–C bonds. All compounds...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 589: Cytotoxic and Anti-Inflammatory Effects of Ent-Kaurane Derivatives Isolated from the Alpine Plant Sideritis hyssopifolia Molecules doi: 10.3390/molecules25030589 Authors: Axelle Aimond Kevin Calabro Coralie Audoin Elodie Olivier Mélody Dutot Pauline Buron Patrice Rat Olivier Laprévote Soizic Prado Emmanuel Roulland Olivier P. Thomas Grégory Genta-Jouve This paper reports the isolation and structural characterization of four...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 593: A Versatile Approach to Access Trimetallic Complexes Based on Trisphosphinite Ligands Molecules doi: 10.3390/molecules25030593 Authors: Juan Miranda-Pizarro Macarena G. Alférez M. Dolores Fernández-Martínez Eleuterio Álvarez Celia Maya Jesús Campos A straightforward method for the preparation of trisphosphinite ligands in one step, using only commercially available reagents (1,1,1-tris(4-hydroxyphenyl)ethane and chlorophosphines) is described....
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 590: The Possible Role of the Nitroso-Sulfide Signaling Pathway in the Vasomotoric Effect of Garlic Juice Molecules doi: 10.3390/molecules25030590 Authors: Berenyiova Grman Misak Golas Cuchorova Cacanyiova The beneficial cardiovascular effects of garlic have been reported in numerous studies. The major bioactive properties of garlic are related to organic sulfides. This study aimed to investigate whether garlic juice works exclusively due...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 588: Characterization of Lysine Acetyltransferase Activity of Recombinant Human ARD1/NAA10 Molecules doi: 10.3390/molecules25030588 Authors: Tam Thuy Lu Vo Ji-Hyeon Park Eun Ji Lee Yen Thi Kim Nguyen Byung Woo Han Hien Thi Thu Nguyen Kyo Cheol Mun Eunyoung Ha Taeg Kyu Kwon Kyu-Won Kim Chul-Ho Jeong Ji Hae Seo Arrest defective 1 (ARD1), also known as N(alpha)-acetyltransferase 10 (NAA10) was originally identified as an N-terminal...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 585: ICT and AIE Characteristics Two Cyano-Functionalized Probes and Their Photophysical Properties, DFT Calculations, Cytotoxicity, and Cell Imaging Applications Molecules doi: 10.3390/molecules25030585 Authors: Tarai Huang Das Pan Zhang Gu Yan Qu Yang Two probes, AIE-1 and AIE-2, were synthesized to investigate the effect of substitutional functional group on aggregation (aggregation-caused quenching (ACQ) or aggregation-induced...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 586: The In Vitro Activity of Essential Oils against Helicobacter pylori Growth and Urease Activity Molecules doi: 10.3390/molecules25030586 Authors: Korona-Glowniak Glowniak-Lipa Ludwiczuk Baj Malm The anti-H. pylori properties of 26 different commercial essential oils were examined in vitro by MIC (minimal inhibitory concentration) determination for the reference strain H. pylori ATCC 43504. We selected 9 essential oils with different anti-Helicobacter...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 583: Diagnostic Potential of FT-IR Fingerprinting in Botanical Origin Evaluation of Laurus nobilis L. Essential Oil is Supported by GC-FID-MS Data Molecules doi: 10.3390/molecules25030583 Authors: Ordoudi Papapostolou Kokkini Tsimidou The last years, non-targeted fingerprinting by Fourier-transform infrared (FT-IR) spectroscopy has gained popularity as an alternative to classical gas chromatography (GC)-based methods because it may allow fast, green,...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 587: Assessment of Pesticide Residue Content in Polish Agricultural Soils Molecules doi: 10.3390/molecules25030587 Authors: Ukalska-Jaruga Smreczak Siebielec Pesticides belong to a group of xenobiotics harmful to humans and wildlife, whose fate and activity depends on their susceptibility to degradation. Therefore, the monitoring of their residue level in agricultural soils is very important because it provides very valuable information on the actual...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 584: Excited State Lifetimes of Sulfur-Substituted DNA and RNA Monomers Probed Using the Femtosecond Fluorescence Up-Conversion Technique Molecules doi: 10.3390/molecules25030584 Authors: Brister Gustavsson Crespo-Hernández Sulfur-substituted DNA and RNA nucleobase derivatives (a.k.a., thiobases) are an important family of biomolecules. They are used as prodrugs and as chemotherapeutic agents in medical settings, and as photocrosslinker molecules in...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 591: Development and Application of a Novel QuEChERS Method for Monitoring of Tributyltin and Triphenyltin in Bottom Sediments of the Odra River Estuary, North Westernmost Part of Poland Molecules doi: 10.3390/molecules25030591 Authors: Kucharski Drzewicz Nałęcz-Jawecki Mianowicz Skowronek Giebułtowicz A Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) extraction method combined with Liquid Chromatography-Tandem Mass Spectrometry...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 578: Small Molecules Targeting the Specific Domains of Histone-Mark Readers in Cancer Therapy Molecules doi: 10.3390/molecules25030578 Authors: Huihui Zhu Tao Wei Yong Cai Jingji Jin Epigenetic modifications (or epigenetic tags) on DNA and histones not only alter the chromatin structure, but also provide a recognition platform for subsequent protein recruitment and enable them to acquire executive instructions to carry out specific intracellular biological...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 582: Induced Hydrophilicity and In Vitro Preliminary Osteoblast Response of Polyvinylidene Fluoride (PVDF) Coatings Obtained via MAPLE Deposition and Subsequent Thermal Treatment Molecules doi: 10.3390/molecules25030582 Authors: Dumitrescu Neacsu Necula Bonciu Marascu Cimpean Moldovan Rotaru Dinca Dinescu Recent advancements in biomedicine have focused on designing novel and stable interfaces that can drive a specific cellular...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 581: Iron(II) Spin Crossover Complexes with 4,4’-Dipyridylethyne—Crystal Structures and Spin Crossover with Hysteresis Molecules doi: 10.3390/molecules25030581 Authors: Dankhoff Lochenie Weber Three new iron(II) 1D coordination polymers with cooperative spin crossover behavior showing thermal hysteresis loops were synthesized using N2O2 Schiff base-like equatorial ligands and 4,4’-dipyridylethyne as a bridging, rigid axial linker. One of those...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 580: Amyloid-beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro
Molecules, Vol. 25, Pages 580: Amyloid-beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro Molecules doi: 10.3390/molecules25030580 Authors: Köppen Schulze Machner Wermann Eichentopf Guthardt Hähnel Klehm Kriegeskorte Hartlage-Rübsamen Morawski von Hörsten Demuth Roßner Schilling Alzheimer’s disease (AD) and Parkinson’s disease (PD), including dementia with Lewy bodies (DLB), account for the majority...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 577: Phytochemistry and Comprehensive Chemical Profiling Study of Flavonoids and Phenolic Acids in the Aerial Parts of Allium Mongolicum Regel and Their Intestinal Motility Evaluation Molecules doi: 10.3390/molecules25030577 Authors: Yongzhe Dong Jingya Ruan Zhijuan Ding Wei Zhao Mimi Hao Ying Zhang Hongyu Jiang Yi Zhang Tao Wang To clarify whether flavonoids and phenols in Allium mongolicum Regel have the effect of improving gastrointestinal...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 579: Spectroscopic Methods Used in Implant Material Studies Molecules doi: 10.3390/molecules25030579 Authors: Lach Jurczak Karska Kubiś Szymańska Rodziewicz-Motowidło It is recognized that interactions between most materials are governed by their surface properties and manifest themselves at the interface formed between them. To gain more insight into this thin layer, several methods have been deployed. Among them, spectroscopic methods...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 576: Naphthoquinone Derivatives with Anti-Inflammatory Activity from Mangrove-Derived Endophytic Fungus Talaromyces sp. SK-S009 Molecules doi: 10.3390/molecules25030576 Authors: Hongju Liu Chong Yan Changqun Li Tingting You Zhigang She Twelve 1, 4-naphthoquinone derivatives, including two new (1 and 2) and 10 known (3–12), were obtained from endophytic fungus Talaromyces sp. SK-S009 isolated from the fruit of Kandelia obovata. All structures...
Wed Jan 29, 2020 02:00
Molecules, Vol. 25, Pages 575: Molecular Mechanisms of the Anti-Cancer Effects of Isothiocyanates from Cruciferous Vegetables in Bladder Cancer Molecules doi: 10.3390/molecules25030575 Authors: Mastuo Miyata Yuno Mukae Otsubo Mitsunari Ohba Sakai Abstract: Bladder cancer (BC) is a representative of urological cancer with a high recurrence and metastasis potential. Currently, cisplatin-based chemotherapy and immune checkpoint inhibitors are used as standard...
Wed Jan 29, 2020 02:00
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