1am6cl-w1rla.htmlAmerican Journal of Otolaryngology_ Alert 23 January.eml 2ax0g5-8o5sa.htmlAnesthesiology Online First.eml 3azg4g-6fk2f.htmlAnnales de Dermatologie et de Vénéréologie _ Volume 147, Issue 1 Eaux thermales, thermes et thermalisme.eml 4ass6x-gk3ia.htmlAnnals of Tourism Research _ Volume 80.eml 5abkuk-w616x.htmlAntibiotics, Volume 9, Issue 1 (January 2020) Table of Contents.eml 6apnbw-ioslw.htmlAntioxidants, Volume 9, Issue 1 (January 2020) Table of Contents.eml 7ai9o2-grxwv.htmlArthroplasty,...
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LifeLife, Vol. 10, Pages 9: A Strategy for Combinatorial Cavity Design in De Novo ProteinsLife, Vol. 10, Pages 9: A Strategy for Combinatorial Cavity Design in De Novo Proteins Life doi: 10.3390/life10020009 Authors: Karas Hecht Protein sequence space is vast; nature uses only an infinitesimal fraction of possible sequences to sustain life. Are there solutions to biological problems other than those provided by nature? Can we create artificial proteins that sustain life? To investigate these questions,...
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AntioxidantsAntioxidants, Vol. 9, Pages 98: Improved Tetanic Force and Mitochondrial Calcium Homeostasis by Astaxanthin Treatment in Mouse Skeletal MuscleAntioxidants, Vol. 9, Pages 98: Improved Tetanic Force and Mitochondrial Calcium Homeostasis by Astaxanthin Treatment in Mouse Skeletal Muscle Antioxidants doi: 10.3390/antiox9020098 Authors: Sztretye Singlár Szabó Angyal Balogh Vakilzadeh Szentesi Dienes Csernoch Background: Astaxanthin (AX) a marine carotenoid is a powerful natural antioxidant...
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The impact of body mass index on severity of cervical spine fracture: A retrospective cohort study: Stephanie Choo, Nikhil Jain, Azeem Tariq Malik, Tania Gennell, Elizabeth YuJournal of Craniovertebral Junction and Spine 2019 10(4):224-228Background: No study has evaluated the relationship between increasing BMI and severity/type of cervical spine injuries.Aims and Objectives: The objective of our study was to study the impact of body mass index (BMI) on severity of cervical spine fracture.Methods:...
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Surgical, clinical, and radiological outcomes of occipitocervical fusion using the plate–screw–rod system with allograft in craniocervical instability: Mihir Upadhyaya, Sanyam Jain, Neilakuo Kire, Zahir Merchant, Vishal Kundnani, Ankit PatelJournal of Craniovertebral Junction and Spine 2019 10(4):216-223Objective: We evaluated surgical, clinical, and radiological outcomes of posterior occipitocervical fusion (OCF) using plate–rod–screw construct supplemented with allograft in cases of occipitocervical...
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Impact of imaging modality, age, and gender on craniocervical junction angles in adults without structural pathology: Ibrahim Hussain, Graham M Winston, Jacob Goldberg, Cloe Curri, Nicholas Williams, J Levi Chazen, Jeffrey P Greenfield, Ali A BaajJournal of Craniovertebral Junction and Spine 2019 10(4):240-246Context: Multiple angles of the craniocervical junction (CCJ) are associated with pathological conditions and surgical outcomes, including the clivo-axial angle (CXA), clival slope (CS), and...
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Lumbar radiculopathy: Outcome analysis following treatment by only fixation – A report of an early experience of 44 cases: Atul Goel, Abhinandan Patil, Abhidha Shah, Survendra Rai, Ravikiran Vutha, Shashi Ranjan, Nilesh Bakale, Tejas VajaJournal of Craniovertebral Junction and Spine 2019 10(4):203-209Objective: An alternative novel form of surgical treatment for patients having prolapsed or bulging intervertebral disc, with or without associated osteophyte, related lumbar radiculopathy by "only fixation"...
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Unstable Hangman's fracture: Anterior or posterior surgery?: Jwalant Yogesh Kumar Patel, Vishal G Kundnani, Suraj Kuriya, Saijyot Raut, Mohit MeenaJournal of Craniovertebral Junction and Spine 2019 10(4):210-215Context: Literature evaluating the efficacy and long-term clinico-radiological outcomes of anterior cervical discectomy and fusion (ACDF) and posterior fixation at C2–C3 for the treatment of unstable hangman's fractures is scanty.Aims: The aim of this study is to compare the efficacy, clinical-radiological...
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Nasogastric tube in anterior cervical spine surgery, is it necessary?: Arvind Gopalrao Kulkarni, Tushar Satish Kunder, Ashwinkumar V KhandgeJournal of Craniovertebral Junction and Spine 2019 10(4):199-202Background: The aim of this article was to verify the utility of nasogastric (NG) tube in primary anterior cervical surgeries. Palpating and identifying the NG tube introduced during induction is one of the ways of preventing esophageal injuries during surgery. It may also be used as a conduit for...
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Stent augmentation of an anterior odontoid screw for type 2 odontoid fracture-dislocation in the elderly population: Report of two cases and literature review: Saurabh Kapoor, Oded Herschkovich, Corrado Lucantoni, Bronek BoszczykJournal of Craniovertebral Junction and Spine 2019 10(4):254-258The fixation of type 2 odontoid fractures poses significant challenges in the elderly population due to coexistent osteoporosis and communition resulting in a high failure rate with conventional anterior screw...
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Tethered cord and Chiari formation: Analysis of treatment in a relatively rare clinical situation: Atul Goel, Shashi Ranjan, Abhidha Shah, Sagar Bhambere, Hardik DarjiJournal of Craniovertebral Junction and Spine 2019 10(4):247-249A 32-year-old male patient was operated for tethered cord associated with spinal lipoma. Further investigations showed the presence of basilar invagination, Chiari formation, and extensive syringomyelia. His neurological symptoms continued to worsen after the surgery, and...
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The use of platelet-rich fibrin in lumbar interbody fusion in lytic spondylolisthesis: Joseph Gamal Boktor, Ahmed Maher Sultan, Awf AlShahwani, Ahmed Samir Barakat, Wael Koptan, Yasser ElmiliguiJournal of Craniovertebral Junction and Spine 2019 10(4):234-239Study Design: This was a retrospective observational study.Aim: The aim of this study was to evaluate the effectiveness of applying the platelet-rich fibrin (PRF) with bone graft in accelerating the rate of lumbar interbody fusion.Settings and...
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Hypertension and proteinuria as clinical biomarkers of response to bevacizumab in glioblastoma patients: AbstractIntroductionArterial hypertension and proteinuria are common side effects of antiangiogenic treatment and might represent a biomarker of response in patients with glioblastoma. The aim of this study was to assess the impact of these side effects in predicting therapeutic response to second line chemotherapy with bevacizumab.MethodsWe evaluated clinical and survival data of glioblastoma...
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Rate of change in maximum 18 F-FDOPA PET uptake and non-enhancing tumor volume predict malignant transformation and overall survival in low-grade gliomas: AbstractPurposeTo examine whether the rate of change in maximum 18F-FDOPA PET uptake and the rate of change in non-enhancing tumor volume could predict malignant transformation and residual overall survival (OS) in low grade glioma (LGG) patients who received serial 18F-FDOPA PET and MRI scans.Methods27 LGG patients with ≥ 2 18F-FDOPA PET and MRI...
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Implantation of carmustine wafers (Gliadel ® ) for high-grade glioma treatment. A 9-year nationwide retrospective study: AbstractBackgroundCarmustine wafers (CW) are approved to treat newly or recurrent high-grade gliomas (HGG). Widespread use has been limited regarding some doubtful uncertainties about their efficacy, related increased risk of infection and expensive cost.ObjectiveTo describe the epidemiology of CW implantation, search for related complications, long-term survival and associated...
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Perioperative fatigue in patients with diffuse glioma: AbstractPurposeFew studies have assessed fatigue in relation to glioma surgery. The purpose of this study was to explore the prevalence of pre- and postoperative high fatigue, perioperative changes, and factors associated with pre- and postoperative high fatigue in patients undergoing primary surgery for diffuse glioma.MethodsA total of 112 adult patients were prospectively included. Patient-reported fatigue was assessed before and one month...
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Random X chromosome inactivation in patients with Klinefelter syndrome: AbstractBackgroundX chromosome inactivation (XCI) is an indispensable process in the development of human female embryos. Reportedly, XCI occurs when a blastocyst contains 10–12 embryonic progenitor cells. To date, it remains unclear whether XCI ratios are normally preserved in Klinefelter syndrome (KS) patients with 47,XXY karyotype.MethodsWe examined XCI ratios in 18 KS patients through DNA methylation analysis for the polymorphic...
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Childhood horse and donkey bites; a single tertiary health center experience in a rural area: Ibrahim Hakan Bucak, Kasım Turgut, Habip Almis, Mehmet TurgutAvicenna Journal of Medicine 2020 10(1):1-5Background: The aim of this study was to examine the characteristics of patients presenting to a pediatric emergency department in a rural province of Turkey due to horse and donkey bites and to analyze whether these features differ from those of more common animal bites in rural areas. Materials and Methods:...
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Work-related musculoskeletal disorders among clinical laboratory workers: Atheer F AlNekhilan, Anfal M AlTamimi, Bothainah Y AlAqeel, Alanoud A AlHawery, Shoog F AlFadhel, Emad M MasuadiAvicenna Journal of Medicine 2020 10(1):29-34Aims and Objectives: The aim of this study was to estimate the prevalence and risk factors of work-related musculoskeletal disorders (WMSDs) among clinical laboratory workers. Materials and Methods: This questionnaire-based cross-sectional study included the clinical laboratory...
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Status of 25-hydroxy vitamin D level in simple febrile seizures and its correlation with recurrence of seizures: Jehangir A Bhat, Tasleem Arif Bhat, Sajad A Sheikh, Zubair A Wani, Roshan AraAvicenna Journal of Medicine 2020 10(1):6-9Background: Febrile seizures are associated with a lot of modifiable and nonmodifiable risk factors. Extensive research is currently going on to discover more and more risk factors of febrile seizures, so that they can be modified to decrease their incidence and recurrence....
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Robot‐assisted gastrectomy for gastric cancer in a patient with a colostomy: A case report with adaptive techniques and technical points: AbstractRobot‐assisted surgery is considered a standard option for procedures on many organs. However, there are still few reports of useful adaptations for various patient conditions. We were able to safely perform robot‐assisted distal gastrectomy on a patient with a colostomy. A 75‐year‐old man presented with gastric cancer, type 0‐IIc, 2.5 cm in diameter. Before...
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Nano-graphene oxide/polyurethane nanofibers: mechanically flexible and myogenic stimulating matrix for skeletal tissue engineering: Journal of Tissue Engineering, Volume 11, Issue , January-December 2020. For skeletal muscle engineering, scaffolds that can stimulate myogenic differentiation of cells while possessing suitable mechanical properties (e.g. flexibility) are required. In particular, the elastic property of scaffolds is of importance which helps to resist and support the dynamic conditions...
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Clinical study of octacalcium phosphate and collagen composite in oral and maxillofacial surgery: Journal of Tissue Engineering, Volume 11, Issue , January-December 2020. Octacalcium phosphate and its collagen composite have been recognized as bone substitute materials possessing osteoconductivity and biodegradation properties. We evaluated the effectiveness of octacalcium phosphate and its collagen composite used for bone augmentation in major oral and maxillofacial surgeries in a clinical trial....
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Cyclin D1 and BRAF V600E Immunohistochemical Staining in Pulmonary Langerhans Cell Histiocytosis.: Related ArticlesCyclin D1 and BRAF V600E Immunohistochemical Staining in Pulmonary Langerhans Cell Histiocytosis.Histopathology. 2020 Jan 21;:Authors: Pors J, Churg AAbstract Pulmonary Langerhans Cell Histiocytosis (PLCH) is a form of Langerhans Cell Histiocytosis (LCH) that typically occurs in the lungs of adult cigarette smokers 1 . The pathogenesis of PLCH is unclear, but the discovery of...
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What We Can Find Beyond the Classic Neuroimaging Findings of Congenital Zika Virus Syndrome?: Related ArticlesWhat We Can Find Beyond the Classic Neuroimaging Findings of Congenital Zika Virus Syndrome?Eur Neurol. 2020 Jan 22;:1-8Authors: Niemeyer B, Hollanda R, Muniz B, Marchiori EAbstract BACKGROUND: In 1947, Zika virus (ZIKV) was first discovered in Monkeys, in Zika Forest, in Uganda, Africa. Five years later, (1952) the first human Zika infection was detected in Nigeria, Africa. After...
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Ferroptosis: a novel mechanism of artemisinin and its derivatives in cancer therapy.: Related ArticlesFerroptosis: a novel mechanism of artemisinin and its derivatives in cancer therapy.Curr Med Chem. 2020 Jan 21;:Authors: Zhu S, Yu Q, Huo C, Li Y, He L, Ran B, Chen J, Li Y, Liu WAbstract BACKGROUND: Artemisinin is a sesquiterpene lactone compound with a special peroxide bridge that is tightly linked to the cytotoxicity involved in fighting malaria and cancer. Artemisinin and its derivatives...
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Neuronal Development-Related miRNAs as Biomarkers for Alzheimer's disease, Depression, Schizophrenia and Ionizing Radiation Exposure.: Related ArticlesNeuronal Development-Related miRNAs as Biomarkers for Alzheimer's disease, Depression, Schizophrenia and Ionizing Radiation Exposure.Curr Med Chem. 2020 Jan 21;:Authors: Segaran RC, Chan LY, Wang H, Sethi G, Tang FRAbstract Radiation exposure may induce Alzheimer disease (AD), depression or schizophrenia. A number of experimental and clinical...
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Is Technical-grade Chlordane an Obesogen?: Related ArticlesIs Technical-grade Chlordane an Obesogen?Curr Med Chem. 2020 Jan 21;:Authors: Silva JF, Moreira BP, Rato L, Pereira ML, Oliveira PF, Alves MGAbstract The prevalence of obesity has tripled in recent decades and is now considered an alarming public health problem. In recent years, a group of endocrine disruptors, known as obesogens, have been directly linked to the obesity epidemic. Its etiology is generally associated with a sedentary...
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Monoclonal antibodies carried in drug delivery nanosystems as a strategy for cancer treatment.: Related ArticlesMonoclonal antibodies carried in drug delivery nanosystems as a strategy for cancer treatment.Curr Med Chem. 2020 Jan 21;:Authors: Silvestre ALP, Oshiro-Júnior JA, Garcia C, Turco BO, da Silva Leite JM, de Lima Damasceno BPG, Soares JCM, Chorilli MAbstract Monoclonal antibodies carried in nanosystems have been extensively studied and reported as a promising tool for the treatment...
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New aspects of monoamine oxidase B inhibitors: the key role of halogens to open the golden door.: Related ArticlesNew aspects of monoamine oxidase B inhibitors: the key role of halogens to open the golden door.Curr Med Chem. 2020 Jan 21;:Authors: Mathew B, Carradori S, Guglielmi P, Sahab Uddin M, Kim HAbstract A large plethora of drugs and promising lead compounds contain halogens in their structures. The introduction of such moieties strongly modulates their physical-chemical features as...
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Case of extranodal natural killer/T-cell lymphoma, nasal type with CCR3 and CXCR3 expression.: Related ArticlesCase of extranodal natural killer/T-cell lymphoma, nasal type with CCR3 and CXCR3 expression.Clin Exp Dermatol. 2020 Jan 21;:Authors: Omori I, Kamijo H, Suga H, Miyagaki T, Taoka K, Toyama K, Kurokawa M, Sato SAbstract Extranodal natural killer/T-cell lymphoma, nasal type (ENKL), is a rare non-Hodgkin`s lymphoma which is strongly associated with latent infection of Epstein-Barr virus...
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First reported cases of Actinic folliculitis treated successfully with topical retinoid.: Related ArticlesFirst reported cases of Actinic folliculitis treated successfully with topical retinoid.Clin Exp Dermatol. 2020 Jan 22;:Authors: Rahman S, Powell J, Al-Ismail DAbstract Actinic Folliculitis (AF) is a rare recurrent seasonal photodermatosis, relatively newly characterised by non pruritic, monomorphic pustules and papules appearing 4 - 24 hours after exposure to sunlight. Lesions usually...
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Efficacy and Safety of Duvelisib Following Disease Progression on Ofatumumab in Patients with Relapsed/Refractory CLL or SLL in the DUO Crossover Extension Study.: Related ArticlesEfficacy and Safety of Duvelisib Following Disease Progression on Ofatumumab in Patients with Relapsed/Refractory CLL or SLL in the DUO Crossover Extension Study.Clin Cancer Res. 2020 Jan 21;:Authors: Davids MS, Kuss BJ, Hillmen P, Montillo M, Moreno C, Essell J, Lamanna N, Nagy Z, Tam CS, Stilgenbauer S, Ghia P, Delgado...
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[Digitalization and use of artificial intelligence in microvascular reconstructive facial surgery].: Related Articles[Digitalization and use of artificial intelligence in microvascular reconstructive facial surgery].Chirurg. 2020 Jan 21;:Authors: Goetze E, Thiem DGE, Gielisch M, Al-Nawas B, Kämmerer PWAbstract BACKGROUND: When using digitalization and artificial intelligence (AI), large amounts of data (big data) are produced, which can be processed by computers and used in the field of microvascular-reconstructive...
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[Artificial intelligence in general and visceral surgery].: Related Articles[Artificial intelligence in general and visceral surgery].Chirurg. 2020 Jan 21;:Authors: Wilhelm D, Ostler D, Müller-Stich B, Lamadé W, Stier A, Feußner HAbstract Artificial intelligence procedures will find special fields of application also in general and visceral surgery. These will not only be limited to intraoperative surgical applications but also extend to perioperative processes, education and training as...
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[Fournier's gangrene as special form of necrotizing fasciitis].: Related Articles[Fournier's gangrene as special form of necrotizing fasciitis].Chirurg. 2020 Jan 21;:Authors: Maier S, Eckmann CAbstract Fournier's gangrene is a special form of necrotizing soft tissue infection (NSTI) and can affect the genital, perineal and perianal regions. Although the disease is named after Fournier, it was first documented by Baurienne in 1764. He described it as idiopathic rapidly progressive gangrene...
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Impaired Saccade Adaptation in Tremor-Dominant Cervical Dystonia-Evidence for Maladaptive Cerebellum.: Related ArticlesImpaired Saccade Adaptation in Tremor-Dominant Cervical Dystonia-Evidence for Maladaptive Cerebellum.Cerebellum. 2020 Jan 22;:Authors: Mahajan A, Gupta P, Jacobs J, Marsili L, Sturchio A, Jinnah HA, Espay AJ, Shaikh AGAbstract We examined the role of the cerebellum in patients with tremor-dominant cervical dystonia by measuring the adaptive capacity of rapid reflexive eye...
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p62 promotes bladder cancer cell growth by activating KEAP1/NRF2-dependent antioxidative response.: Related Articlesp62 promotes bladder cancer cell growth by activating KEAP1/NRF2-dependent antioxidative response.Cancer Sci. 2020 Jan 22;:Authors: Li T, Jiang D, Wu KAbstract p62 is associated with two major cellular defense mechanisms against metabolic and oxidative stress, autophagy and the Kelch-like ECH-associated protein 1(KEAP1)-NF-E2-related factor 2 (NRF2) system. Recent studies indicate...
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Modulation of Nqo1 Activity Intercepts Anoikis Resistance and Reduces Metastatic Potential of Hepatocellular Carcinoma.: Related ArticlesModulation of Nqo1 Activity Intercepts Anoikis Resistance and Reduces Metastatic Potential of Hepatocellular Carcinoma.Cancer Sci. 2020 Jan 22;:Authors: Shimokawa M, Yoshizumi T, Itoh S, Iseda N, Sakata K, Yugawa K, Toshima T, Harada N, Ikegami T, Mori MAbstract The processing of intracellular reactive oxygen species (ROS) by nuclear factor erythroid-derived...
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Interactions between Auditory and Vestibular Modalities during Stimulation with a Combined Vestibular and Cochlear Prosthesis.: Related ArticlesInteractions between Auditory and Vestibular Modalities during Stimulation with a Combined Vestibular and Cochlear Prosthesis.Audiol Neurootol. 2020 Jan 22;25(1-2):96-108Authors: Phillips JO, Ling L, Nowack A, Rebollar B, Rubinstein JTAbstract BACKGROUND: A combined vestibular and cochlear prosthesis may restore hearing and balance to patients who...
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Home-based evaluation of executive function (Home-MET) for older adults with mild cognitive impairment.: Related ArticlesHome-based evaluation of executive function (Home-MET) for older adults with mild cognitive impairment.Arch Gerontol Geriatr. 2020 Jan 16;87:104012Authors: Lai FH, Yan EW, Yu KKAbstract INTRODUCTION: Executive function helps older adults maintain their activities of daily living by making plans, setting goals, and carrying them out successfully. It is important for their...
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Development and Validation of the BREAST-Q Breast-Conserving Therapy Module.: Related ArticlesDevelopment and Validation of the BREAST-Q Breast-Conserving Therapy Module.Ann Surg Oncol. 2020 Jan 21;:Authors: Klassen AF, Dominici L, Fuzesi S, Cano SJ, Atisha D, Locklear T, Gregorowitsch ML, Tsangaris E, Morrow M, King T, Pusic ALAbstract BACKGROUND: In breast cancer surgery, patient-reported outcome measures are needed to measure outcomes best reported by patients (e.g., psychosocial well-being)....
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Toxicity of Immune Checkpoint Inhibitors: Considerations for the Surgeon.: Related ArticlesToxicity of Immune Checkpoint Inhibitors: Considerations for the Surgeon.Ann Surg Oncol. 2020 Jan 21;:Authors: Helmink BA, Roland CL, Kiernan CM, Wargo JAAbstract BACKGROUND: The use of immunotherapeutic agents, specifically immune checkpoint inhibitors (ICIs) for solid malignancies, is rapidly rising, and many new agents and treatment combinations are in development. However, ICIs have a unique side-effect...
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Validation of a Novel Nomogram for Prediction of Local Relapse after Surgery for Invasive Breast Carcinoma.: Related ArticlesValidation of a Novel Nomogram for Prediction of Local Relapse after Surgery for Invasive Breast Carcinoma.Ann Surg Oncol. 2020 Jan 21;:Authors: Corso G, Maisonneuve P, Massari G, Invento A, Pravettoni G, De Scalzi A, Intra M, Galimberti V, Morigi C, Lauretta M, Sacchini V, Veronesi PAbstract BACKGROUND: Around 7% of women who undergo breast-conserving surgery (BCS)...
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Extent of Peritoneal Resection for Peritoneal Metastases: Looking Beyond a Complete Cytoreduction.: Related ArticlesExtent of Peritoneal Resection for Peritoneal Metastases: Looking Beyond a Complete Cytoreduction.Ann Surg Oncol. 2020 Jan 21;:Authors: Bhatt A, Glehen OAbstract Completeness of cytoreduction is one of the most important prognostic factors impacting outcomes of cytoreductive surgery (CRS). To what extent the surrounding normal peritoneum needs to be removed is not known. We...
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Four-Point Computed Tomography Scores for Evaluation of Occult Peritoneal Metastasis in Patients with Gastric Cancer: A Region-to-Region Comparison with Staging Laparoscopy.: Related ArticlesFour-Point Computed Tomography Scores for Evaluation of Occult Peritoneal Metastasis in Patients with Gastric Cancer: A Region-to-Region Comparison with Staging Laparoscopy.Ann Surg Oncol. 2020 Jan 21;:Authors: Li ZY, Tang L, Li ZM, Li YL, Fu J, Zhang Y, Li XT, Ying XJ, Ji JFAbstract BACKGROUND: Preoperative...
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External Approach to Buccal Fat Excision in Facelift: Anatomy and Technique.: Related ArticlesExternal Approach to Buccal Fat Excision in Facelift: Anatomy and Technique.Aesthet Surg J. 2020 Jan 22;:Authors: Surek CC, Kochuba AL, Said SA, Cho KH, Swanson M, Duraes E, McBride J, Drake RL, Zins JEAbstract BACKGROUND: Masculinization of the face is a common finding in facelift patients. It is attributed to deflation and decent of the midface-jowls coupled with skin laxity. Fullness is evident...
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Sensitivity of the Nipple-Areola Complex in Reduction Mammaplasty Following Periareolar Dermis Section.: Related ArticlesSensitivity of the Nipple-Areola Complex in Reduction Mammaplasty Following Periareolar Dermis Section.Aesthet Surg J. 2020 Jan 22;:Authors: de Sá JZ, Braga ACCR, Barreto RHC, Ramos ADS, de Oliveira Rodrigues AE, Santa-Cruz F, Aguiar JLAAbstract BACKGROUND: Preservation of the periareolar dermis, after de-epithelization in reduction mammaplasty, may result in a limitation...
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Incidence and Radiological Findings of Incidental Sinus Opacifications in Patients Undergoing Septoplasty or Septorhinoplasty.: Related ArticlesIncidence and Radiological Findings of Incidental Sinus Opacifications in Patients Undergoing Septoplasty or Septorhinoplasty.Ann Otol Rhinol Laryngol. 2020 Feb;129(2):122-127Authors: Kim SH, Oh JS, Jang YJAbstract OBJECTIVES: Although the routine use of computed tomography (CT) is controversial, it is employed in the preoperative screening of patients...
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Duration of one-lung ventilation as a risk factor for postoperative pulmonary complications after McKeown esophagectomy.: Related ArticlesDuration of one-lung ventilation as a risk factor for postoperative pulmonary complications after McKeown esophagectomy.Tumori. 2020 Jan 22;:300891619900805Authors: Lai G, Guo N, Jiang Y, Lai J, Li Y, Lai RAbstract OBJECTIVE: To assess whether the duration of one-lung ventilation (OLV) affects postoperative pulmonary complications after McKeown esophagectomy...
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Effects of the Carrier Phrase on Word Recognition Performances by Younger and Older Listeners Using Two Stimulus Paradigms.: Related ArticlesEffects of the Carrier Phrase on Word Recognition Performances by Younger and Older Listeners Using Two Stimulus Paradigms.J Am Acad Audiol. 2020 Jan 22;:0Authors: Wilson RH, Sanchez VAAbstract BACKGROUND: In the 1950s, with monitored live voice testing, the vu meter time constant and the short durations and amplitude modulation characteristics of monosyllabic...
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Congenital heart disease in children: Orofacial myofunctional aspects, eating behavior and facial temperature.: Related ArticlesCongenital heart disease in children: Orofacial myofunctional aspects, eating behavior and facial temperature.Int J Pediatr Otorhinolaryngol. 2020 Jan 15;131:109883Authors: Barbosa MDG, Castelo PM, Ferreira CLP, Haddad DS, Chiari BM, Santana MV, Bommarito SAbstract OBJECTIVE: To characterize the eating behavior, orofacial, speech myofunctional conditions, and facial...
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Significance of bulky mass and residual tumor-Treated with or without consolidative radiotherapy-To the risk of relapse in DLBCL patients.: Related ArticlesSignificance of bulky mass and residual tumor-Treated with or without consolidative radiotherapy-To the risk of relapse in DLBCL patients.Cancer Med. 2020 Jan 22;:Authors: Tokola S, Kuitunen H, Turpeenniemi-Hujanen T, Kuittinen OAbstract Bulky and residual tumor are considered to increase the risk of relapse in diffuse large B-cell lymphoma...
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ELF1-mediated LUCAT1 promotes choroidal melanoma by modulating RBX1 expression.: Related ArticlesELF1-mediated LUCAT1 promotes choroidal melanoma by modulating RBX1 expression.Cancer Med. 2020 Jan 22;:Authors: Wang L, Tang D, Wu T, Sun FAbstract Long noncoding RNAs (lncRNAs) are essential regulators of gene expression and biological behaviors. However, the contribution of lncRNA LUCAT1 to choroidal melanoma (CM) remains unexplored. Here, we examined the expression of LUCAT1 in CM cells by...
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Accuracy and Reliability of Smartphone Self-Test Audiometry in Community Clinics in Low Income Settings: A Comparative Study.: Related ArticlesAccuracy and Reliability of Smartphone Self-Test Audiometry in Community Clinics in Low Income Settings: A Comparative Study.Ann Otol Rhinol Laryngol. 2020 Jan 22;:3489420902162Authors: Sandström J, Swanepoel D, Laurent C, Umefjord G, Lundberg TAbstract BACKGROUND: There is a lack of hearing health care globally, and tele-audiology and mobile technologies...
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Chemical, Electrical and Tactile Sensitivity Changes After Middle Ear Surgery.: Related ArticlesChemical, Electrical and Tactile Sensitivity Changes After Middle Ear Surgery.Ann Otol Rhinol Laryngol. 2020 Jan 22;:3489419901136Authors: Pellegrino R, Hummel TAbstract OBJECTIVE/HYPOTHESIS: Taste disturbances are often seen in patients after middle ear surgery due to the stress received by an unprotected chorda tympani. It has also been reported that loss in tactile sensitivity may accompany...
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A tonal-language benefit for pitch in normally-hearing and cochlear-implanted children.: Related ArticlesA tonal-language benefit for pitch in normally-hearing and cochlear-implanted children.Sci Rep. 2019 01 14;9(1):109Authors: Deroche MLD, Lu HP, Kulkarni AM, Caldwell M, Barrett KC, Peng SC, Limb CJ, Lin YS, Chatterjee MAbstract In tonal languages, voice pitch inflections change the meaning of words, such that the brain processes pitch not merely as an acoustic characterization of sound...
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Recellularization of auricular cartilage via elastase-generated channels.: Related ArticlesRecellularization of auricular cartilage via elastase-generated channels.Biofabrication. 2019 04 26;11(3):035012Authors: Lehmann J, Nürnberger S, Narcisi R, Stok KS, van der Eerden BCJ, Koevoet WJLM, Kops N, Ten Berge D, van Osch GJAbstract Decellularized tissue matrices are promising substrates for tissue generation by stem cells to replace poorly regenerating tissues such as cartilage. However, the...
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Mucormycosis diagnosed during induction chemotherapy in five pediatric patients with acute lymphoblastic leukemia.: Related ArticlesMucormycosis diagnosed during induction chemotherapy in five pediatric patients with acute lymphoblastic leukemia.Pediatr Blood Cancer. 2019 09;66(9):e27834Authors: Aftandilian C, Eguiguren L, Mathew R, Messner AAbstract Mucormycosis in pediatric oncology patients is a rare invasive fungal infection associated with significant morbidity and mortality. We describe...
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The etiological evaluation of sensorineural hearing loss in children.: Related ArticlesThe etiological evaluation of sensorineural hearing loss in children.Eur J Pediatr. 2019 Aug;178(8):1195-1205Authors: van Beeck Calkoen EA, Engel MSD, van de Kamp JM, Yntema HG, Goverts ST, Mulder MF, Merkus P, Hensen EFAbstract This study aims to evaluate the etiology of pediatric sensorineural hearing loss (SNHL). A total of 423 children with SNHL were evaluated, with the focus on the determination...
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Risk and Prognostic Factors for Rupture of Intracranial Aneurysms During Endovascular Embolization.: Related ArticlesRisk and Prognostic Factors for Rupture of Intracranial Aneurysms During Endovascular Embolization.World Neurosurg. 2019 Sep;129:e641-e649Authors: Jiang C, Luan D, Wang C, Liu Q, Han J, Li GAbstract OBJECTIVE: Intraoperative aneurysm rupture (IPR) always results in a poor prognosis for the patient. However, the risk factors of IPR are unclear. In this article, the risk factors...
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Periorbital dermatitis in patients receiving docetaxel in combination chemotherapy.: Related ArticlesPeriorbital dermatitis in patients receiving docetaxel in combination chemotherapy.BMJ Case Rep. 2019 Jul 21;12(7):Authors: Tabata MM, Kwong BAbstract Recognition of new cutaneous side effects of combination chemotherapy can help prevent unnecessary cessation or reduction of cancer therapy. Periorbital rash has not been found with docetaxel alone, but here, we report it as a result of combination...
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Assessment of Tracheostomy and Laryngectomy Knowledge among Non-Otolaryngology Physicians.: Related ArticlesAssessment of Tracheostomy and Laryngectomy Knowledge among Non-Otolaryngology Physicians.Ann Otol Rhinol Laryngol. 2020 Feb;129(2):115-121Authors: Hsieh TY, Timbang L, Kuhn M, Brodie H, Squires LAbstract OBJECTIVE: Identify knowledge deficits about alternate airways (AAs) (tracheostomy and laryngectomy) among physicians across multiple specialties a tertiary institution and to assess...
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Does Insurance Status Impact Delivery of Care with Upper Airway Stimulation for OSA?: Related ArticlesDoes Insurance Status Impact Delivery of Care with Upper Airway Stimulation for OSA?Ann Otol Rhinol Laryngol. 2020 Feb;129(2):128-134Authors: Patel J, Topf MC, Huntley C, Boon MAbstract OBJECTIVE: To understand differences in patient demographics, insurance-related treatment delays, and average waiting times for Medicare and private insurance patients undergoing upper airway stimulation...
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Metastatic non-muscle invasive bladder can-cer with cervical lymph node metastasis.: Related ArticlesMetastatic non-muscle invasive bladder can-cer with cervical lymph node metastasis.Int Braz J Urol. 2019 Nov-Dec;45(6):1270-1274Authors: Garrido-Abad P, Martin LG, Zarra KV, Menendez AD, Arjona MFAbstract Bladder cancer is a common cancer that may present as superficial, invasive, or metastatic disease. Non-muscle-invasive bladder cancer (NMIBC) represents the majority of bladder cancer diagnoses,...
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The Role of Vitamin D in Primary Headache-from Potential Mechanism to Treatment.: Related ArticlesThe Role of Vitamin D in Primary Headache-from Potential Mechanism to Treatment.Nutrients. 2020 Jan 17;12(1):Authors: Nowaczewska M, Wiciński M, Osiński S, Kaźmierczak HAbstract Some studies have suggested a link between vitamin D and headache; however, the underlying physiological mechanisms are unclear. We aimed to summarize the available evidence on the relationship between vitamin D and the...
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The Long Non-Coding RNA Prader Willi/Angelman Region RNA5 (PAR5) Is Downregulated in Anaplastic Thyroid Carcinomas Where It Acts as a Tumor Suppressor by Reducing EZH2 Activity.: Related ArticlesThe Long Non-Coding RNA Prader Willi/Angelman Region RNA5 (PAR5) Is Downregulated in Anaplastic Thyroid Carcinomas Where It Acts as a Tumor Suppressor by Reducing EZH2 Activity.Cancers (Basel). 2020 Jan 17;12(1):Authors: Pellecchia S, Sepe R, Decaussin-Petrucci M, Ivan C, Shimizu M, Coppola C, Testa D, Calin...
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Dual vascular free transverse rectus abdominis myocutaneous flap for hemifacial reconstruction in a vessel-depleted neck.: Related ArticlesDual vascular free transverse rectus abdominis myocutaneous flap for hemifacial reconstruction in a vessel-depleted neck.Arch Plast Surg. 2020 Jan;47(1):88-91Authors: Lee SH, You HJ, Lee YH, Kim DWAbstract Cutaneous squamous cell carcinoma (SCC) is the second most common skin malignancy. This report describes the case of an unusual extensive SCC involving...
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Cone-Beam Computed Tomography Incidental Findings in Individuals With Cleft Lip and Palate.: Related ArticlesCone-Beam Computed Tomography Incidental Findings in Individuals With Cleft Lip and Palate.Cleft Palate Craniofac J. 2020 Jan 22;:1055665619897469Authors: Santos G, Ickow I, Job J, Brooker JE, Dvoracek LA, Rigby E, Shah N, Chen W, Branstetter B, Schuster LAAbstract OBJECTIVES: The use of cone-beam computed tomography (CBCT) is well-established in clinical practice. This study seeks...
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Radiation dose-painting with protons vs. photons for head-and-neck cancer.: Related ArticlesRadiation dose-painting with protons vs. photons for head-and-neck cancer.Acta Oncol. 2020 Jan 21;:1-9Authors: Håkansson K, Smulders B, Specht L, Zhu M, Friborg J, Rasmussen JH, Bentzen SM, Vogelius IRAbstract Background: Dose-painting has recently been investigated in early-phase trials in head-and-neck cancer (HNC) with the aim of improving local tumor control. At the same time proton therapy has...
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Do patients benefit from physiotherapy for shoulder dysfunction following neck dissection? A systematic review.: Related ArticlesDo patients benefit from physiotherapy for shoulder dysfunction following neck dissection? A systematic review.J Laryngol Otol. 2020 Jan 22;:1-5Authors: Harris ASAbstract OBJECTIVE: Accessory nerve palsy affects a proportion of patients following neck dissection, and results in shoulder dysfunction and regional pain. This project aimed to establish the evidence...
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Otogenic intracranial complications: a 10-year retrospective review in KwaZulu-Natal, South Africa.: Related ArticlesOtogenic intracranial complications: a 10-year retrospective review in KwaZulu-Natal, South Africa.J Laryngol Otol. 2020 Jan 22;:1-5Authors: Khuzwayo ZB, Enicker BAbstract OBJECTIVES: To analyse the data for patients with otogenic intracranial complications during the study period and draw a comparison with internationally published literature. METHOD: A retrospective,...
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Eustachian tube dysfunction in candidates for surgery for obstructive sleep apnoea syndrome.: Related ArticlesEustachian tube dysfunction in candidates for surgery for obstructive sleep apnoea syndrome.J Laryngol Otol. 2020 Jan 22;:1-5Authors: Ungar OJ, Rosenzweig E, Betito HR, Cavel O, Oron Y, Handzel OAbstract BACKGROUND: Defining the risk factors for Eustachian tube dysfunction can facilitate its prevention. It is hypothesised that Eustachian tube dysfunction as measured by the Eustachian...
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CUE-101, a Novel HPV16 E7-pHLA-IL-2-Fc Fusion Protein, Enhances Tumor Antigen Specific T Cell Activation for the Treatment of HPV16-Driven Malignancies.: Related ArticlesCUE-101, a Novel HPV16 E7-pHLA-IL-2-Fc Fusion Protein, Enhances Tumor Antigen Specific T Cell Activation for the Treatment of HPV16-Driven Malignancies.Clin Cancer Res. 2020 Jan 21;:Authors: Quayle SN, Girgis N, Thapa DR, Merazga Z, Kemp MM, Histed A, Zhao F, Moreta M, Ruthardt P, Hulot S, Nelson A, Kraemer LD, Beal DR, Witt L,...
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Effect of pterygopalatine blockade on perioperative stress and inflammatory outcomes following paediatric cataract surgery.: Related ArticlesEffect of pterygopalatine blockade on perioperative stress and inflammatory outcomes following paediatric cataract surgery.Reg Anesth Pain Med. 2020 Jan 20;:Authors: Oleshchenko I, Cok OY, Iureva T, Zabolotskii D, Kripak AAbstract BACKGROUND: General anesthesia is required to perform pediatric cataract surgery. To reduce severity of surgical intervention...
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A nationwide population-based study to access the risk of metachronous esophageal cancers in head and neck cancer survivors.: Related ArticlesA nationwide population-based study to access the risk of metachronous esophageal cancers in head and neck cancer survivors.Sci Rep. 2020 Jan 21;10(1):884Authors: Tseng CM, Wang HH, Lee CT, Tai CM, Tseng CH, Chen CC, Tsai YN, Chen TH, Hsu MH, Wang CC, Hwang TZ, Wang HP, Wang WLAbstract How long esophageal screening should be performed for, and on which...
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A treatise on endothelial biology and exosomes: homage to Theresa Maria Listowska Whiteside.: Related ArticlesA treatise on endothelial biology and exosomes: homage to Theresa Maria Listowska Whiteside.HNO. 2020 Jan 21;:Authors: Ludwig N, Lotze MTAbstract Exosomes are the current primary research focus of Dr. Theresa L. Whiteside. They are key mediators of intercellular communication in the head and neck, as well as other sites. Their effects in the tumor microenvironment are manifold and...
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Efficacy and Timing of Neonatal Ear Correction Molding.: Related ArticlesEfficacy and Timing of Neonatal Ear Correction Molding.Aesthetic Plast Surg. 2020 Jan 21;:Authors: Zhuang Q, Wei N, Zhou Q, Wang H, Wu Y, Chen Z, Yu D, Wang P, Shi HAbstract BACKGROUND AND AIM: Given the incidence of congenital auricular anomalies varies racially, this study aimed to investigate the efficacy and timing of ear correction molding in infants with auricular anomalies. MATERIALS AND METHODS: A total...
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Safety of radiotherapy for hemodialysis patients with cancer.: Related ArticlesSafety of radiotherapy for hemodialysis patients with cancer.Int J Clin Oncol. 2020 Jan 21;:Authors: Hirota H, Ito K, Kageyama SI, Tamamoto F, Karasawa K, Yoshimura RAbstract BACKGROUND: The number of hemodialysis (HD) patients is increasing worldwide, and they are at a higher risk of cancer than the general population. Because HD patients are more likely to have inflammation, radiotherapy (RT)-induced adverse...
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Thyroglossal Duct Cyst Occupying Posterior Hyoid Space with Endolaryngeal Extension Presenting After Neck Trauma.: Related ArticlesThyroglossal Duct Cyst Occupying Posterior Hyoid Space with Endolaryngeal Extension Presenting After Neck Trauma.Ann Otol Rhinol Laryngol. 2020 Jan 22;:3489419901140Authors: Bosco S, Cohn JE, Evarts M, Papajohn P, Lesser RAbstract OBJECTIVE: Thyroglossal duct cysts are the most common congenital neck mass. They typically present as a painless midline neck mass...
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Accuracy of WatchPAT for the Diagnosis of Obstructive Sleep Apnea in Patients with Chronic Obstructive Pulmonary Disease.: Related ArticlesAccuracy of WatchPAT for the Diagnosis of Obstructive Sleep Apnea in Patients with Chronic Obstructive Pulmonary Disease.COPD. 2020 Jan 22;:1-6Authors: Jen R, Orr JE, Li Y, DeYoung P, Smales E, Malhotra A, Owens RLAbstract The co-existence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA), termed the overlap syndrome (OVS),...
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Downregulation of long non-coding RNA NR2F2-AS1 inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cells by upregulating the expression of PTEN.: Related ArticlesDownregulation of long non-coding RNA NR2F2-AS1 inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cells by upregulating the expression of PTEN.Oncol Lett. 2020 Feb;19(2):1145-1150Authors: Qin H, Qin CAbstract The novel long non-coding RNA NR2F2-AS1 has been characterized as an oncogene...
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Expression of miR-34a and Ki67 in nasopharyngeal carcinoma and the relationship with clinicopathological features and prognosis.: Related ArticlesExpression of miR-34a and Ki67 in nasopharyngeal carcinoma and the relationship with clinicopathological features and prognosis.Oncol Lett. 2020 Feb;19(2):1273-1280Authors: Wei L, Shi C, Zhang YAbstract Expression levels of miR-34a and Ki67 in nasopharyngeal carcinoma (NPC) and the relationship with clinicopathological features and prognosis were...
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Involvement of the TGF-β1 pathway in caveolin-1-associated regulation of head and neck tumor cell metastasis.: Related ArticlesInvolvement of the TGF-β1 pathway in caveolin-1-associated regulation of head and neck tumor cell metastasis.Oncol Lett. 2020 Feb;19(2):1298-1304Authors: Sun J, Lu Y, Yu C, Xu T, Nie G, Miao B, Zhang XAbstract Head and neck squamous cell carcinoma (HNSCC) is the sixth most frequent malignancy with a 5-year survival rate of 54%. Therefore, disease management improvement...
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Primary Ewing's sarcoma of the petroclival bone: A case report and literature review.: Related ArticlesPrimary Ewing's sarcoma of the petroclival bone: A case report and literature review.Surg Neurol Int. 2020;11:6Authors: Schartz D, Divakar P, Tafe L, Paydarfar JAbstract Background: Primary Ewing's sarcoma (ES) is typically seen within the long bones, vertebrae, or pelvis. Uncommonly, it can be found within the cranium among the rarest locations for primary ES are the skull base, in particular,...
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Stress, Burnout, and Associated Risk Factors in Medical Students.: Related ArticlesStress, Burnout, and Associated Risk Factors in Medical Students.Cureus. 2020 Jan 12;12(1):e6633Authors: Shadid A, Shadid AM, Shadid A, Almutairi FE, Almotairi KE, Aldarwish T, Alzamil O, Alkholaiwi F, Khan SUAbstract Objectives To determine the prevalence of and the risk factors associated with burnout and stress for medical students in Saudi Arabia. Methods A cross-sectional, survey-based study was distributed...
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Identifying patterns of failure and secondary primary malignancies in HPV-related oropharyngeal squamous cell carcinomas.: Related ArticlesIdentifying patterns of failure and secondary primary malignancies in HPV-related oropharyngeal squamous cell carcinomas.Future Oncol. 2020 Jan 22;:Authors: Holstead R, Rasul R, Golden A, Kamdar D, Ghaly M, Teckie S, Frank D, Fantasia J, Seetharamu NAbstract Aim: To compare patterns and rates of recurrence in patients with oropharyngeal squamous cell carcinoma...
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Adenoid cystic carcinoma of head and neck. A 5-year retrospective study: Experience in a single third-level reference center.: Related ArticlesAdenoid cystic carcinoma of head and neck. A 5-year retrospective study: Experience in a single third-level reference center.Cir Cir. 2020;88(1):34-40Authors: Gamboa-Hoil SI, Silva-Godínez JC, Abrego-Vásquez JAAbstract Introduction: Adenoid cystic carcinoma (ACC) is a rare tumor, with an annual incidence of 3-4.5 cases/million. Materials and...
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Sino-Nasal Outcome Test-22: Cross-cultural Adaptation, and Validation in Russian Speaking Patients.: Related ArticlesSino-Nasal Outcome Test-22: Cross-cultural Adaptation, and Validation in Russian Speaking Patients.Clin Otolaryngol. 2020 Jan 22;:Authors: Eisenbach N, Matot S, Nemet A, Marshak T, Ronen OAbstract BACKGROUND: Chronic rhinosinusitis (CRS) is a relatively common disease which significantly affects the patient's quality of life (QoL). Sino-Nasal Outcome Test-22 (SNOT-22) is a...
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Correlation of chemotherapy costs with quality of life in nasopharyngeal cancer patients.: Related ArticlesCorrelation of chemotherapy costs with quality of life in nasopharyngeal cancer patients.J Basic Clin Physiol Pharmacol. 2020 Jan 23;:Authors: Romdhoni AC, Aulia R, Utaminingtyas RP, Suharjono , Alderman CPAbstract Background Nasopharyngeal cancer (NPC) is the most common neck/head cancer occurring in Indonesia and is the fourth most malignant after breast cancer, cervical cancer, and...
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Immunohistochemical analysis of cancer-associated fibroblasts and podoplanin in head and neck cancer.: Related ArticlesImmunohistochemical analysis of cancer-associated fibroblasts and podoplanin in head and neck cancer.Med Oral Patol Oral Cir Bucal. 2020 Jan 22;:Authors: Ramos-Vega V, Venegas Rojas B, Donoso Torres WAbstract BACKGROUND: To immunohistochemically evaluate the association between the presence of cancer-associated fibroblasts (CAFs) and the tumour expression of podoplanin (PDPN)...
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Artificial Neural Networks allow Response Prediction in Squamous Cell Carcinoma of the Scalp Treated with Radiotherapy.: Related ArticlesArtificial Neural Networks allow Response Prediction in Squamous Cell Carcinoma of the Scalp Treated with Radiotherapy.J Eur Acad Dermatol Venereol. 2020 Jan 22;:Authors: Damiani G, Grossi E, Berti E, Conic RR, Radhakrishna U, Pacifico A, Bragazzi NL, Piccinno R, Linder DAbstract BACKGROUND: Epithelial neoplasms of the scalp account for approximately 2%...
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Side effects and complications of injection laryngoplasty for treatment of congenital type 1 laryngeal clefts.: Related ArticlesSide effects and complications of injection laryngoplasty for treatment of congenital type 1 laryngeal clefts.Int J Pediatr Otorhinolaryngol. 2020 Jan 16;131:109886Authors: Ramazani F, Isaac A, Johannsen W, El-Hakim HAbstract INTRODUCTION: Injection laryngoplasty (IL) is a brief, minimally invasive procedure involving injection of agents to augment the interarytenoid...
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Gene variability in matrix metalloproteinases in patients with recurrent aphthous stomatitis: AbstractBackgroundThe development of recurrent aphthous stomatitis (RAS), inflammatory disease of oral mucosa, is influenced by both environmental and genetic factors. The aim of this study was to investigate polymorphisms located in seven genes coding different types of matrix metalloproteinases (MMPs) ‐ collagenases (MMP1, MMP8, MMP13), gelatinases (MMP2, MMP9), stromelysin (MMP3), and membrane type metalloproteinase...
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Efficacy of Scaffold‐Mediated Localized Chemotherapy in Cancer: A systematic review of current research: AbstractObjectiveTo assess the efficacy of scaffold‐mediated localized chemotherapy in cancer.MethodsDatabases including PubMed, Cochrane Library, and SCOPUS were searched for articles reporting the use of scaffold‐mediated localized drug delivery in cancer. Essential data including scaffold fabrication material and methods, drug dosage and release duration and its effect on the cancer cells were...
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Hyperkeratotic Skin Adverse Events Induced by Anticancer Treatments: A Comprehensive Review: AbstractHyperkeratotic skin adverse events are a group of toxic effects, characterized by the disruption of epidermal homeostasis and interaction with keratinocyte proliferation/differentiation or keratinocyte survival, and frequently reported with systemic anticancer treatments. These types of reactions include hand–foot skin reaction or palmoplantar keratoderma, induced psoriasis, keratosis pilaris-like...
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Epidemiology and clinical outcomes of hospitalizations for acute respiratory or febrile illness and laboratory-confirmed influenza among pregnant women during six influenza seasons, 2010-2016: AbstractBackgroundPregnant women are at increased risk of seasonal influenza hospitalizations, but data about the epidemiology of severe influenza among pregnant women remain largely limited to pandemics.MethodsTo describe the epidemiology of hospitalizations for acute respiratory infection or febrile illness...
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Screening Strategies for a Sustainable Endpoint for Gambiense Sleeping Sickness: AbstractBackgroundGambiense human African trypanosomiasis ([gHAT] sleeping sickness) is a vector-borne disease that is typically fatal without treatment. Intensified, mainly medical-based, interventions in endemic areas have reduced the occurrence of gHAT to historically low levels. However, persistent regions, primarily in the Democratic Republic of Congo (DRC), remain a challenge to achieving the World Health Organization's...
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Trained immunity confers broad-spectrum protection against bacterial infections: AbstractBackgroundThe innate immune system recalls a challenge to adapt to a secondary challenge, a phenomenon called trained immunity. Training involves cellular metabolic, epigenetic and functional reprogramming, but how broadly trained immunity protects from infections is unknown. For the first time, we addressed whether trained immunity provides protection in a large panel of preclinical models of infections.MethodsMice...
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A class II-restricted CD8ɣ13 T cell clone protects during Chlamydia muridarum genital tract infection: AbstractThe T cell response to chlamydia genital tract infections in humans and mice is unusual because the majority of antigen-specific CD8 T cells are not class I-restricted, referred to as "unrestricted" or "atypical". We previously reported that a subset of unrestricted murine chlamydia-specific CD8 T cells had a cytokine polarization pattern that included IFN-ɣ and IL-13. Here we investigated...
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Population-level human secretor status is associated with genogroup 2 type 4 norovirus predominance: AbstractBackgroundNoroviruses are a leading cause of acute gastroenteritis. Genogroup 2 type 4 (GII.4) has been the dominant norovirus genotype worldwide since its emergence in the mid-1990s. Individuals with a functional fucosyltransferase-2 gene, known as secretors, have increased susceptibility to GII.4 noroviruses. We hypothesized that this individual-level trait may drive GII.4 norovirus predominance...
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Large-scale screening and identification of novel pathogenic Staphylococcus aureus genes using a silkworm infection model: AbstractThe regulatory network of virulence factors produced by the opportunistic pathogen Staphylococcus aureus is unclear, and the functions of many uncharacterized genes in its genome remain to be elucidated. In this study, we screened 380 genes whose function was unassigned utilizing gene-disrupted transposon mutants of the community-acquired methicillin-resistant S. aureus...
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Oncostatin-M is a prognostic biomarker and inflammatory mediator for sepsis: AbstractBackgroundOncostatin-M (OSM) is a pleiotropic cytokine of the IL-6 family. The role of OSM in sepsis remains unknown.MethodsSerum OSM level was determined and analyzed in septic patients on day of intensive care unit (ICU) admission. Furthermore, the effects of OSM on polymicrobial sepsis induced by cecal ligation and puncture (CLP) were assessed.ResultsOn day of ICU admission, septic patients had significantly higher...
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Humoral and Mucosal Immune Responses to Human Norovirus in the Elderly: AbstractBACKGROUNDMost information on mucosal and systemic immune response to norovirus infection is derived from human challenge studies, birth cohort studies, or vaccine trials in healthy adults. However, few data are available on immune responses to norovirus in the elderly.MATERIALSTo study the mucosal and systemic immune response against norovirus, 43 long-term care facilities (LTCFs) were enrolled prospectively in 2010-2014....
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Drug resistance assessment following administration of RSV fusion inhibitor presatovir to participants experimentally infected with respiratory syncytial virus: AbstractBackgroundPresatovir is an oral respiratory syncytial virus (RSV) fusion inhibitor targeting RSV F protein. In a double-blind, placebo-controlled study in healthy adults experimentally infected with RSV (Memphis-37b), presatovir significantly reduced viral load and clinical disease severity in a dose-dependent manner.MethodsViral...
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Role for maternal asthma in severe human metapneumovirus lung disease susceptibility in children: AbstractBackgroundSeverity of human metapneumovirus (hMPV) lower respiratory illness (LRTI) is considered similar to that observed for respiratory syncytial virus (RSV). However, differences in severity between both pathogens have been noted, suggesting degree of illness may vary in different populations. Moreover, a potential association between hMPV and asthma also suggests that hMPV may preferentially...
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In vitro CO 2 9.3-μm short-pulsed laser caries prevention—effects of a newly developed laser irradiation pattern: AbstractCaries prevention with different lasers has been investigated in laboratory studies and clinical pilot trials. Objective of this in vitro study was to assess whether 9.3-μm microsecond short-pulsed CO2 laser irradiation enhances enamel caries resistance without melting, with and without additional fluoride application. Seven groups of enamel, totaling 105 human enamel samples,...
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Light emitting diode (LED) based fluorescence microscopy for tuberculosis detection: a review: AbstractSince time immemorial, tuberculosis (TB) has intimidated the human race owing to its severity. Its socio-economic burden has led to it being a major cause of concern. It is one of the world's major causes of death from a single agent. Since most of the middle- and low-income countries are burdened with TB, sputum smear examination using conventional light microscopy is often the only resort for...
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Photoactivated resveratrol controls intradermal infection by Staphylococcus aureus in mice: a pilot study: AbstractStaphylococcus aureus is one of the main causative agent of infections acquired in both community and hospital environment. In this context, photodynamic therapy (PDT) consists in using a photosensitizer that, activated by light, evokes the formation of reactive oxygen species (ROS), which lead to the death of microorganisms due to oxidative damage; it is useful tool since this action,...
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Blue light therapy to treat candida vaginitis with comparisons of three wavelengths: an in vitro study: AbstractAnti-fungal blue light (ABL) therapies have been widely studied to treat various microbial infections in the literature. The blue light with wavelengths ranging from 400 to 470 nm has been reported to be effective to inhibit various kinds of bacteria and fungi. The existing studies usually report the viability rates of the pathogens under the irradiation of the blue light with different...
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A comparative study of the efficacy of fractional neodymium-doped yttrium aluminum garnet (Nd:YAG) laser therapy alone and in combination with erbium:YAG laser therapy: tracing and objective measurement of melanin index in macular amyloidosis: AbstractMacular amyloidosis (MA) is a common form of primary localized cutaneous amyloidosis, characterized by the eruption of brown pigments of the skin with a rippled pattern. MA can be of cosmetic concern for patients, and its treatment is challenging. In...
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Transurethral endoscopic enucleation of the prostate using a diode laser versus bipolar plasmakinetic for benign prostatic obstruction: a meta-analysis: AbstractTo evaluate the clinical efficacy and safety of diode laser enucleation of the prostate (DiLEP) versus bipolar plasma kinetic enucleation of the prostate (PKEP) in the management of benign prostatic hyperplasia (BPH). A systematic literature search was undertaken using PubMed, Embase, Web of Science, Cochrane Library, and CKNI databases to...
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Efficacy and safety of ND:YAG 1064 nm lasers for photoepilation: a systematic review: AbstractUsing light sources in phototherapy has presented promising results regarding several types of facial and body skin affections for centuries. The neodymium-doped yttrium aluminum garnet (ND:YAG) 1064 nm laser has become a standard treatment in dermatology for dermatological disturbances related to the pilous follicle and the structures surrounding it. Despite the reports of its clinical benefits, few scientific...
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Evaluation of the effect of optic zone diameter selection on high-order aberrations in photorefractive keratectomy excimer laser treatment: AbstractTo evaluate the postoperative higher-order aberration (HOA) differences and visual quality outcomes of wavefront-optimised photorefractive keratectomy (PRK) surgery in 6.5-mm and 7.0-mm optic zones. The study included 136 eyes of 68 patients who underwent wavefront-optimised PRK surgery for myopia or myopia with astigmatism. Q values, third-order coma...
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In vitro evaluation of the hemostatic effect of method involving the combined use of Hydrofit ® and Spongel ®: AbstractObjectiveWe developed an effective hemostatic method using Hydrofit® and a hemostatic gelatin sponge (Spongel®). We evaluated the hemostatic effect in comparison to the conventional silicone sheet method.MethodsA simulated circuit was created using the pump of a Nipro ventricular assist system and a prosthetic graft. A hole was made in the graft by a needle and three hemostatic methods...
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Aortobronchial fistula: AbstractAortobronchial fistulas (ABFs) are rare but fatal if left untreated. Hemoptysis is the most common symptom of the patients. ABFs may occur after any thoracic aortic lesions or maneuveurs for these lesions. The treatment of ABF can be surgical or thoracic endovascular aortic repair. Thoracic endovascular aortic repair can be a safe and less invasive procedure for the treatment of ABFs. However, ABFs might occur in much shorter time after thoracic endovascular aortic...
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Emergency thromboembolectomy for impending paradoxical embolism through a patent foramen ovale owing to venous thromboembolism in a severely obese patient: AbstractA severely obese patient with dyspnea and weighing 197 kg presented to us. He experienced an impending paradoxical embolism in the left ventricle caused by a deep vein thrombosis passing through a patent foramen ovale, as well as an acute massive pulmonary thromboembolism. Emergency thromboembolectomy from the right atrium and the bilateral...
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Emergency surgery for hemothorax due to a ruptured pulmonary arteriovenous malformation: AbstractPulmonary arteriovenous malformation (PAVM) is a potential cause of hemothorax. The risk of PAVM rupture is reported to be higher during pregnancy for several reasons, including increased body fluid and a change in hormonal conditions. A 34-year-old pregnant woman suddenly felt right chest pain and dyspnea in the 28th week of gestation. Chest X-ray and computed tomography showed massive right pleural...
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Ivor Lewis vs Mckeown esophagectomy: analysis of operative outcomes from the ACS NSQIP database: AbstractObjectivesIvor Lewis and McKeown esophagectomy are common techniques to treat esophageal cancer. In this study, we aim to compare these two approaches.MethodWe used the American College of Surgeons National Surgical Quality Improvement Project database (2005–2017) to compare both techniques using bivariate analysis after propensity matching.ResultsWe identified 6136 patients with esophagectomy...
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Low-level laser therapy prevents muscle oxidative stress in rats subjected to high-intensity resistance exercise in a dose-dependent manner: AbstractHigh-intensity resistance exercise (RE) increases oxidative stress leading to deleterious effects on muscle performance and recovery. The aim of this study was to assess the effect of applying low-level laser therapy (LLLT) prior to a RE session on muscle oxidative stress and to determine the possible influence of the dosimetric parameters. Female Wistar...
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"Comparative study between the efficacy of fractional CO2 laser, Q-switched Nd:YAG laser (1064 nm), and both types in treatment of keratosis pilaris": AbstractThe aim of this study was to assess and compare the efficacy of fractional CO2 laser, Q-switched Nd:YAG laser (1064 nm), and their combined use in treatment of keratosis pilaris. The study included twenty female patients. For each patient, three areas were randomly assigned to treatment by either fractional CO2 laser (area A) or Q-switched...
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Clinical outcomes of micropulse transscleral cyclophotocoagulation in refractory glaucoma—18 months follow-up: AbstractThe aim of this study is to evaluate the clinical outcomes of micropulse transscleral cyclophotocoagulation (mTSCPC) in cases of refractory glaucoma. Patients with refractory glaucoma were selected to undergo mTSCPC, using the MP3 handpiece from Iridex Laser Systems. Follow-up examinations occurred on a regular basis for 18 months after the procedure. One hundred eyes of 97 patients...
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Laser-induced fluorescence diagnosis of stomach tumor: AbstractThe purpose of this study is to demonstrate the capabilities of laser spectral and video fluorescence diagnosis used for stomach tumors using 5-ALA photosensitizer. The spectroscopic method is presented with an example of a characteristic fluorescence spectrum from stomach with 5-ALA and quantitative statistics. The laser excitation wavelength was 632.8 nm. The analysis of the video system is presented with clinical statistics. The penetration...
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Effects of consumption of contaminated feed with 2,4-dichlorophenoxyacetic acid (2,4-D) on the rat tibia: analysis by Raman spectroscopy and mechanical properties: AbstractStudies reported the harmful effects of 2,4-D on body tissues, provoking changes in the anatomy and physiology of the kidneys, liver, and testicles. Thus, the objective was to evaluate if there were alterations in the bone quality of the tibia of rats submitted to feed consumption that were exposed to three different 2,4-D doses....
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Comparison of the effectiveness of fractional 1550-nm erbium fiber laser and 0.05% tretinoin cream in the treatment of acanthosis nigricans: a prospective, randomized, controlled trial: AbstractAcanthosis nigricans is a common dermatological problem. There are currently limited clinical trials to determine the efficacy and safety of laser treatments. To compare the efficacy of fractional 1550-nm erbium fiber laser versus 0.05% tretinoin cream for the treatment of acanthosis nigricans at neck, a randomized,...
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Effect of photobiomodulation therapy as an adjunct to scaling and root planing in a rat model of ligature-induced periodontitis: a histological and radiographic study: AbstractThis study aimed to histologically and radiographically evaluate the effectiveness of low-intensity laser irradiation of different wavelengths (660 or 808 nm) as an adjunct to scaling and root planing in the treatment of experimental periodontitis in rats. Periodontitis was induced by placing a ligature around the mandibular...
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Efficacy and safety of the picosecond 755-nm alexandrite laser for treatment of dermal pigmentation in Asians—a retrospective study: AbstractQ-Switched laser devices have been a standard treatment modality for dermal pigmentary disorders since the 1990s. However, the adverse events are sometimes intolerable even if the efficacy has been well accepted. These adverse events stop the patient from continuing the treatment and cause other cosmetic issues. Since 2012, the first picosecond laser for cosmetic...
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Efficacy of CO lasers in preventing dental caries in partially erupted first permanent molars: a randomized 18-month clinical trial: AbstractThe aim of this controlled randomized double-blinded clinical trial was to evaluate the use of a CO2 laser with or without topical application of acidulated fluorides in the prevention of dental caries in partially erupted first permanent molars. We selected 61 healthy children at high risk of caries, all between 6 and 8 (7.1 ± 0.8) years of age and with 4 partially...
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Photobiomodulation as an adjunctive therapy for alveolar socket preservation: a preliminary study in humans: AbstractBone remodeling results in loss of alveolar bone height and thickness. Photobiomodulation (PBM) based on photochemical stimulation by low-intensity lasers emerges as an adjunctive therapy for alveolar socket preservation. Our study aimed to evaluate the effects of PBM therapy on alveolar bone repair. Twenty healthy patients in need of bilateral extraction of lower molars were enrolled...
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Photobiomodulation of red and green lights in the repair process of third-degree skin burns: AbstractThe aim of this study was to evaluate the photobiomodulation of red and green lights in the repair process of third-degree skin burns in rats through clinicopathological and immunohistochemical parameters. Sixty male Wistar rats were divided into three groups: control (CTRL) (n = 20), red LED (RED) (n = 20), and green LED (GREEN) (n = 20), with subgroups (n = 5) for each time of euthanasia (7, 14,...
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Effect of 650-nm low-level laser irradiation on c-Jun, c-Fos, ICAM-1, and CCL2 expression in experimental periodontitis: AbstractThis study was designed to investigate the effect of 650-nm low-level laser irradiation (LLLI) as an adjunctive treatment of experimental periodontitis. To investigate possible LLLI-mediated anti-inflammatory effects, we utilized an experimental periodontitis (EP) rat model and analyzed c-Jun, c-Fos, ICAM-1, and CCL2 gene expressions on PB leukocytes and in the gingival...
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Complementary low-level laser therapy for breast cancer-related lymphedema: a pilot, double-blind, randomized, placebo-controlled study: AbstractThis pilot, double-blind, randomized, placebo-controlled study is aimed at evaluating the effectiveness of low-level laser therapy (LLLT) as a complementary treatment to complete decongestive therapy (CDT) treating lymphedema among breast cancer patients for 12 months post-intervention. Study population was breast cancer patients who were diagnosed and referred...
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Swept-source optical coherence tomographic observation on prevalence and variations of cemento-enamel junction morphology: AbstractTo investigate the prevalence of different patterns of cemento-enamel junction (CEJ) morphology under swept-source optical coherence tomography (SS-OCT). One hundred extracted human teeth were used consisting of incisors, premolars, and molars. Each sample was observed for every 500 μm circumferentially along CEJ and OCT images of the pattern were noted. Microscopic observations...
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The impact of photobiomodulation of major salivary glands on caries risk: AbstractDental caries is a complex multifactorial chronic infectious disease guided by several risk or protective factors. Saliva has an important role in caries and the remineralization process. Caries risk assessment is defined as the probability of new caries lesion development or the existing lesion progression in a given time period. Caries diagnostics and risk factor assessment are followed by targeted elimination of...
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Circulating adiposity‐related microRNAs as predictors of the response to a low‐fat diet in subjects with obesity: AbstractRecent studies have revealed the critical role of several microRNAs (miRNAs) in energy homeostasis and metabolic processes and suggest that circulating miRNAs can be used as early predictors of weight loss in the design of precision nutrition. Thus, the aim of this study was to investigate circulating adiposity‐related miRNAs as biomarkers of the response to two specific weight...
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Vitamin B6 inhibits macrophage activation to prevent lipopolysaccharide‐induced acute pneumonia in mice: AbstractMacrophage activation participates in the pathogenesis of pulmonary inflammation. As a coenzyme, vitamin B6 (VitB6) is mainly involved in the metabolism of amino acids, nucleic acids, glycogen and lipids. We have previously reported that activation of AMP‐activated protein kinase (AMPK) produces anti‐inflammatory effects both in vitro and in vivo. Whether VitB6 via AMPK activation prevents...
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Airway epithelial ITGB4 deficiency in early life mediates pulmonary spontaneous inflammation and enhanced allergic immune response: AbstractLung immune responses to respiratory pathogens and allergens are initiated in early life which will further influence the later onset of asthma. The airway epithelia form the first mechanical physical barrier to allergic stimuli and environmental pollutants, which is also the key regulator in the initiation and development of lung immune response. However, the...
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Contralateral occlusion test: The effect of external ear canal occlusion on predicting conductive hearing loss: Publication date: Available online 31 December 2019Source: Acta Otorrinolaringológica EspañolaAuthor(s): Luis Roque Reis, Luís Castelhano, Filipe Correia, Pedro EscadaAbstractIntroduction and objectivesThe contralateral occlusion test (COT) has the potential to allow the quantitative evaluation of unilateral conductive hearing loss. The purpose of this study was to determine the accuracy...
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Valoración de la capacidad pronóstica de la afectación ganglionar de los pacientes con carcinoma de orofaringe en función del estatus HPV: Publication date: Available online 7 January 2020Source: Acta Otorrinolaringológica EspañolaAuthor(s): Jose-Miguel Costa, Anna Sumarroca, Camilo Rodríguez, Alfons Gutiérrez, Jacinto García, Montserrat López, Miquel Quer, Xavier LeónResumenAntecedentes y objetivoDiferentes estudios realizados en poblaciones con una elevada incidencia de infección por HPV han encontrado...
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Perfil clínico y resultados obtenidos en los pacientes tratados mediante implante auditivo del tronco del encéfalo: Publication date: Available online 11 January 2020Source: Acta Otorrinolaringológica EspañolaAuthor(s): Carlos Prieto-Matos, Octavio Garaycochea, Diego Calavia, Manuel Alegre, Bartolomé Bejarano, Alicia Huarte, Ricardo Díez-Valle, José Luis Zubieta, Manuel ManriqueResumenIntroducciónLos implantes cocleares han paliado algunas hipoacusias, pero las relacionadas con alteraciones del nervio...
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Middle Ear Muscle Reflex and Word Recognition in "Normal-Hearing" Adults: Evidence for Cochlear Synaptopathy?: Objectives: Permanent threshold elevation after noise exposure, ototoxic drugs, or aging is caused by loss of sensory cells; however, animal studies show that hair cell loss is often preceded by degeneration of synapses between sensory cells and auditory nerve fibers. The silencing of these neurons, especially those with high thresholds and low spontaneous rates, degrades auditory processing...
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Use of Commercial Virtual Reality Technology to Assess Verticality Perception in Static and Dynamic Visual Backgrounds: Objectives: The Subjective Visual Vertical (SVV) test and the closely related Rod and Disk Test (RDT) are measures of perceived verticality measured in static and dynamic visual backgrounds. However, the equipment used for these tests is variable across clinics and is often too expensive or too primitive to be appropriate for widespread use. Commercial virtual reality technology,...
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Improving Clinical Outcomes in Cochlear Implantation Using Glucocorticoid Therapy: A Review: Cochlear implant surgery is a successful procedure for auditory rehabilitation of patients with severe to profound hearing loss. However, cochlear implantation may lead to damage to the inner ear, which decreases residual hearing and alters vestibular function. It is now of increasing interest to preserve residual hearing during this surgery because this is related to better speech, music perception, and...
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Children With Normal Hearing Are Efficient Users of Fundamental Frequency and Vocal Tract Length Cues for Voice Discrimination: Background: The ability to discriminate between talkers assists listeners in understanding speech in a multitalker environment. This ability has been shown to be influenced by sensory processing of vocal acoustic cues, such as fundamental frequency (F0) and formant frequencies that reflect the listener's vocal tract length (VTL), and by cognitive processes, such as attention...
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Psychometric Properties of Cognitive-Motor Dual-Task Studies With the Aim of Developing a Test Protocol for Persons With Vestibular Disorders: A Systematic Review: Objectives: Patients suffering from vestibular disorders (VD) often present with impairments in cognitive domains such as visuospatial ability, memory, executive function, attention, and processing speed. These symptoms can be attributed to extensive vestibular projections throughout the cerebral cortex and subcortex on the one hand, and...
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Prediction Model for Audiological Outcomes in Patients With GJB2 Mutations: Objectives: Recessive mutations in GJB2 are the most common genetic cause of sensorineural hearing impairment (SNHI) in humans. SNHI related to GJB2 mutations demonstrates a wide variation in audiological features, and there has been no reliable prediction model for hearing outcomes until now. The objectives of this study were to clarify the predominant factors determining hearing outcome and to establish a predictive model...
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Amplitude Modulated Noise for Tinnitus Suppression in Tonal and Noise-Like Tinnitus: Background: The phenomenon of short-term tinnitus suppression by different forms of acoustic stimulation is referred to as residual inhibition (RI). RI can be triggered in the majority of tinnitus cases and was found to be depending on the used intensity, length or types of sounds. Past research already stressed the impact of noise stimulation as well as the superiority of amplitude modulated (AM) pure tones at the...
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Correlation between High-Resolution Computed Tomography Scan Findings and Histological Findings in Human Vestibular End Organs and Surgical Implications: Background: Histological study of vestibular end organs has been challenging due to the difficulty in preserving their structures for histological analysis and due to their complex geometry. Recently, radiology advances have allowed to deepen the study of the membranous labyrinth. Summary: A review and analysis of surgical implications related to...
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The Superiority of the Otolith System: Background: The peripheral vestibular end organ is considered to consist of semi-circular canals (SCC) for detection of angular accelerations and the otoliths for detection of linear accelerations. However, otoliths being phylogenetically the oldest part of the vestibular sensory organs are involved in detection of all motions. Summary: This study elaborates on this property of the otolith organ, as this concept can be of importance for the currently designed...
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Phonak Launches Super-Power Hearing Aid Naída™ Marvel: Phonak today launched Naída Marvel (M), a fully connected, multifunctional super-power hearing aid with universal Bluetooth® connectivity for people with severe-to-profound hearing loss. The integrated Marvel 2.0 technology, including RogerDirect, gives wearers the flexibility to stream the Roger signal directly into both ears, resulting in almost 10 times better-than-normal hearing in noisy situations and over a distance.1 These connectivity...
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Inhibition of miR-217 Protects Against Myocardial Ischemia–Reperfusion Injury Through Inactivating NF-κB and MAPK Pathways: AbstractPurposeRecent studies have demonstrated that miRNAs play a vital role in regulating myocardial ischemia/reperfusion injury (MIRI). MiR-217 has been proven to be implicated in cardiac diseases such as chronic heart failure and cardiac myxoma. However, the role of miR-217 in MIRI is not clear.MethodsA mouse MIRI model was established and the myocardial infarct size was...
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Correlation Between Doppler Derived Carotid Artery Corrected Flow Time and Pressure Transducer Derived Radial Artery Corrected Flow Time: A Prospective Observational Study: AbstractPurposeCarotid artery corrected flow time (cFT) derived from Doppler USG is a known predictor of volume responsiveness. However, it can't be obtained continuously, and is operator dependent. In this prospective study, correlation between Doppler derived carotid artery cFT and pressure transducer derived radial artery cFT...
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Fluorescent Nanoclusters for Imaging of Cells/Stem Cells.: Related ArticlesFluorescent Nanoclusters for Imaging of Cells/Stem Cells.Methods Mol Biol. 2019 Dec 24;:Authors: Molaabasi F, Hajipour-Verdom B, Alipour M, Naghib SMAbstract Imaging of cancer cells and cancer stem cells (CSCs) plays an important role in studying cell biology and tracking cancer development and metastasis. There is a wide interest in targeting cancer cells using fluorescent nanoclusters (NCs) capped in protein due...
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Tracking and Imaging of Transplanted Stem Cells in Animals.: Related ArticlesTracking and Imaging of Transplanted Stem Cells in Animals.Methods Mol Biol. 2019 Dec 24;:Authors: Chikate TR, Tang LAbstract The shortage of organ donors has contributed to the rapid development of cell-based therapy in which stem cells are transplanted and administered to repair or regenerate damaged tissues or organs. The common sources of stem cells are embryonic, mesenchymal, stromal, and induced pluripotent...
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Two Case Reports of Integrated Management of Antibiotic-Resistant Urinary Tract Infection.: Related ArticlesTwo Case Reports of Integrated Management of Antibiotic-Resistant Urinary Tract Infection.Homeopathy. 2020 Jan 20;:Authors: Chand KS, Kapoor PAbstract BACKGROUND: Urinary tract infections (UTIs) are frequent in women. Cystitis after intercourse (post-coital cystitis) accounts for 60% of recurrent cases. Most physicians treat recurrent UTIs (R-UTIs) with multiple courses of antibiotics....
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Efficacy of Homeopathy in Addition to a Multidisciplinary Intervention for Overweight or Obesity in Mexican Adolescents: Study Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial.: Related ArticlesEfficacy of Homeopathy in Addition to a Multidisciplinary Intervention for Overweight or Obesity in Mexican Adolescents: Study Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial.Homeopathy. 2020 Jan 20;:Authors: Macías-Cortés E, Arellano-Álvarez S, Vega-Monroy S, Vera-Pérez...
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Comprehensive Functional Echocardiographic Assessment of Transposition of the Great Arteries: From Fetus to Newborn: AbstractTo improve the understanding of the pathophysiology of transposition of the great arteries with intact ventricular septum (TGA/IVS) and the cardiac remodeling occurring from fetal to neonatal life, we performed a morphometric and functional echocardiographic assessment in fetuses and newborns. This was a prospective case–control study performed in a tertiary referral center,...
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Impact of Clinician Engagement on Implementation of the Pediatric Echocardiography Appropriate Use Criteria: AbstractWe sought to determine whether awareness of the pediatric appropriate use criteria (AUC) affected transthoracic echocardiogram (TTE) ordering by cardiologists; evaluate for differences in classification of an encounter's AUC clinical scenario by investigator chart review compared with clinicians at the time of the encounter; and assess TTE yield by appropriateness rating. AUC clinical...
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Modified Single Repair Technique for Complete Atrioventricular Septal Defect: A Propensity Score Matching Analysis: AbstractThere were controversies about the priority of modified single patch (MSP) technique compared with two-patch (TP) technique for patients with complete atrioventricular septal defect (CAVSD). From 2002 to 2013, patients who diagnosed as balanced CAVSD in our institution were retrospectively included. Patients with unbalanced ventricles or associated anomalies were excluded. The...
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Non-invasive Risk Stratification in Pediatric Ventricular Pre-excitation: AbstractChildren with ventricular pre-excitation are at risk for sudden death. This retrospective pediatric study identified patients > 8 years of age who had undergone electrophysiology study (EPS). Our primary objective was to determine the performance characteristics of non-invasive risk stratification. Subjects were separated into two groups. Group 1 was asymptomatic or had non-specific symptoms (palpitations, chest...
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Recurrence of Cholesteatoma - A Retrospective Study Including 1,006 Patients for More than 33 Years.: Related ArticlesRecurrence of Cholesteatoma - A Retrospective Study Including 1,006 Patients for More than 33 Years.Int Arch Otorhinolaryngol. 2020 Jan;24(1):e18-e23Authors: Møller PR, Pedersen CN, Grosfjeld LR, Faber CE, Djurhuus BDAbstract Introduction Cholesteatomas are benign tumors consisting of skin, and growing inside a retraction pocket in the tympanic membrane. Cholesteatomas...
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THYROID ACROPACHY: A RARE MANIFESTATION OF GRAVES DISEASE IN JOINTS.: Related ArticlesTHYROID ACROPACHY: A RARE MANIFESTATION OF GRAVES DISEASE IN JOINTS.AACE Clin Case Rep. 2019 Nov-Dec;5(6):e369-e371Authors: Perini N, Santos RB, Romaldini JH, Villagelin DAbstractObjective: The objective of this report was to describe a patient with Graves acropachy, a rare manifestation of Graves disease (GD) that is clinically defined by skin tightness, digital clubbing, small-joint pain, and soft tissue edema...
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