Does Osteopathic Manipulative Treatment Induce Autonomic Changes in Healthy Participants? A Thermal Imaging Study. Front Neurosci. 2020;14:887 Authors: Cerritelli F, Cardone D, Pirino A, Merla A, Scoppa F Abstract Osteopathic manipulative treatment (OMT) has been demonstrated to be an effective therapy in several clinical conditions and age groups. Despite the clinical effectiveness, lack of robust data in terms of neurobiological, specifically...
Tue Oct 06, 2020 13:49
Contribution of Five Functional Loci of Dopamine Metabolism-Related Genes to Parkinson's Disease and Multiple System Atrophy in a Chinese Population. Front Neurosci. 2020;14:889 Authors: Chen Y, Ou R, Zhang L, Gu X, Yuan X, Wei QQ, Cao B, Zhao B, Wu Y, Shang H Abstract Background: Impaired dopamine metabolism is associated with Parkinson's disease (PD). Considering the overlap in the clinical and pathological characteristics between PD and...
Tue Oct 06, 2020 13:49
Rapid Cortical Plasticity Induced by Active Associative Learning of Novel Words in Human Adults. Front Neurosci. 2020;14:895 Authors: Razorenova AM, Chernyshev BV, Nikolaeva AY, Butorina AV, Prokofyev AO, Tyulenev NB, Stroganova TA Abstract Human speech requires that new words are routinely memorized, yet neurocognitive mechanisms of such acquisition of memory remain highly debatable. Major controversy concerns the question whether cortical...
Tue Oct 06, 2020 13:49
Telmisartan, an Antagonist of Angiotensin II Receptors, Accentuates Voltage-Gated Na+ Currents and Hippocampal Neuronal Excitability. Front Neurosci. 2020;14:902 Authors: Lai MC, Wu SN, Huang CW Abstract Telmisartan (TEL), a non-peptide blocker of the angiotensin II type 1 receptor, is a widely used antihypertensive agent. Nevertheless, its neuronal ionic effects and how they potentially affect neuronal network excitability remain largely unclear....
Tue Oct 06, 2020 13:49
Does Unilateral Hearing Loss Impair Working Memory? An Italian Clinical Study Comparing Patients With and Without Hearing Aids. Front Neurosci. 2020;14:905 Authors: Della Volpe A, Ippolito V, Roccamatisi D, Garofalo S, De Lucia A, Gambacorta V, Longari F, Ricci G, Di Stadio A Abstract Working memory (WM) function can be reduced in patients suffering from unilateral hearing loss (UHL) and can affect their academic performance. We aimed to compare...
Tue Oct 06, 2020 13:49
Mediation of Cardiac Macrophage Activity via Auricular Vagal Nerve Stimulation Ameliorates Cardiac Ischemia/Reperfusion Injury. Front Neurosci. 2020;14:906 Authors: Chung CH, Bretherton B, Zainalabidin S, Deuchars SA, Deuchars J, Mahadi MK Abstract Background: Myocardial infarction (MI) reperfusion therapy causes paradoxical cardiac complications. Following restoration of blood flow to infarcted regions, a multitude of inflammatory cells are...
Tue Oct 06, 2020 13:49
Chronic Timed Sleep Restriction Attenuates LepRb-Mediated Signaling Pathways and Circadian Clock Gene Expression in the Rat Hypothalamus. Front Neurosci. 2020;14:909 Authors: Sun Q, Liu Y, Wei W, Wu D, Lin R, Wen D, Jia L Abstract The sleep duration of adolescents has continued to decline over the past 20 years. Sleep insufficiency is one of the most important risk factors for obesity, but the mechanisms underlying the association are unclear....
Tue Oct 06, 2020 13:49
Potential Pathways for Circadian Dysfunction and Sundowning-Related Behavioral Aggression in Alzheimer's Disease and Related Dementias. Front Neurosci. 2020;14:910 Authors: Todd WD Abstract Patients with Alzheimer's disease (AD) and related dementias are commonly reported to exhibit aggressive behavior and other emotional behavioral disturbances, which create a tremendous caretaker burden. There has been an abundance of work highlighting the...
Tue Oct 06, 2020 13:49
Neuroanatomical Alterations in Patients With Tinnitus Before and After Sound Therapy: A Voxel-Based Morphometry Study. Front Neurosci. 2020;14:911 Authors: Wei X, Lv H, Wang Z, Liu C, Ren P, Zhang P, Chen Q, Liu Y, Zhao P, Gong S, Yang Z, Wang Z Abstract According to previous studies, many neuroanatomical alterations have been detected in patients with tinnitus. However, few studies have reported on the morphological changes observed following...
Tue Oct 06, 2020 13:49
Suppression of spastin Mutant Phenotypes by Pak3 Loss Implicates a Role for Reactive Glia in AD-HSP.
Suppression of spastin Mutant Phenotypes by Pak3 Loss Implicates a Role for Reactive Glia in AD-HSP. Front Neurosci. 2020;14:912 Authors: Ozdowski EF, Wentzell JS, Engert SM, Abbott H, Sherwood NT Abstract Neurodegenerative mechanisms due to mutations in spastin currently center on neuronal defects, primarily in microtubule and endomembrane regulation. Spastin loss in Drosophila larvae compromises neuronal microtubule distribution, alters synaptic...
Tue Oct 06, 2020 13:49
Subthalamic Stimulation Inhibits Bladder Contraction by Modulating the Local Field Potential and Catecholamine Level of the Medial Prefrontal Cortex. Front Neurosci. 2020;14:917 Authors: Yamamoto T, Sakakibara R, Uchiyama T, Kuwabara S Abstract Aims: The patients with Parkinson's disease (PD) present with lower urinary tract symptoms (LUTS), but the efficacy of subthalamic nucleus deep brain stimulation (STN-DBS) on LUTS is unknown. The medial...
Tue Oct 06, 2020 13:49
Lactate-Protected Hypoglycemia (LPH). Front Neurosci. 2020;14:920 Authors: Goodwin ML, Gladden LB, Nijsten MWN Abstract Here, we provide an overview of the concept of a lactate-protected hypoglycemia ("LPH"), originally proposed as lowering glucose while simultaneously increasing lactate concentration as a method by which tumors might be targeted. Central to this hypothesis is that lactate can act as a critical salvage fuel for the central...
Tue Oct 06, 2020 13:49
Upregulation of C Terminus of Hsc70-Interacting Protein Attenuates Apoptosis and Procoagulant Activity and Facilitates Brain Repair After Traumatic Brain Injury. Front Neurosci. 2020;14:925 Authors: Chen H, Jing Y, Xu Z, Yang D, Ju S, Guo Y, Tian H, Xue L Abstract Traumatic brain injury (TBI) could highly induce coagulopathy through breaking the dynamic balance between coagulation and fibrinolysis systems, which may be a major contributor to...
Tue Oct 06, 2020 13:49
The Discovery and Characterization of Targeted Perikaryal-Specific Brain Lesions With Excitotoxins. Front Neurosci. 2020;14:927 Authors: Coyle JT, Schwarcz R Abstract The neurotoxic action of glutamic acid was first described by Lucas and Newhouse, who demonstrated neural degeneration in the inner layers of the neonatal mouse retina after systemic treatment with L-glutamate. Olney extended these findings by showing that neuronal degeneration...
Tue Oct 06, 2020 13:49
Intravenous Administration of Pyroglutamyl Apelin-13 Alleviates Murine Inflammatory Pain via the Kappa Opioid Receptor. Front Neurosci. 2020;14:929 Authors: Lv S, Zhang X, Feng Y, Zhou Y, Cui B, Yang Y, Wang X Abstract Apelin is an endogenous neuropeptide, which has wide distribution in central nervous system and peripheral tissues. Pyroglutamyl apelin-13 [(pyr)apelin-13] is the major apelin isoform in human plasma. However, the role of peripheral...
Tue Oct 06, 2020 13:49
Machine Learning Methods for Fluorescence Lifetime Imaging (FLIM) Based Label-Free Detection of Microglia. Front Neurosci. 2020;14:931 Authors: Sagar MAK, Cheng KP, Ouellette JN, Williams JC, Watters JJ, Eliceiri KW Abstract Automated computational analysis techniques utilizing machine learning have been demonstrated to be able to extract more data from different imaging modalities compared to traditional analysis techniques. One new approach...
Tue Oct 06, 2020 13:49
Dietary Exposure to Excess Saturated Fat During Early Life Alters Hippocampal Gene Expression and Increases Risk for Behavioral Disorders in Adulthood. Front Neurosci. 2020;14:527258 Authors: Page KC, Anday EK Abstract Purpose: Maternal and postnatal diets result in long-term changes in offspring brain and behavior; however, the key mediators of these developmental changes are not well-defined. In this study, we investigated the impact of maternal...
Tue Oct 06, 2020 13:49
Commentary: Effects of ALS-associated TANK binding kinase 1 mutations on protein-protein interactions and kinase activity. Front Neurosci. 2020;14:551006 Authors: Freischmidt A, Brenner D, Ludolph AC, Andersen PM, Weishaupt JH PMID: 33013311 [PubMed]
Tue Oct 06, 2020 13:49
Resting-State Functional Connectivity Patterns Predict Acupuncture Treatment Response in Primary Dysmenorrhea. Front Neurosci. 2020;14:559191 Authors: Yu S, Xie M, Liu S, Guo X, Tian J, Wei W, Zhang Q, Zeng F, Liang F, Yang J Abstract Primary dysmenorrhea (PDM) is a common complaint in women throughout the menstrual years. Acupuncture has been shown to be effective in dysmenorrhea; however, there are large interindividual differences in patients'...
Tue Oct 06, 2020 13:49
miRNA Alterations Elicit Pathways Involved in Memory Decline and Synaptic Function in the Hippocampus of Aged Tg4-42 Mice. Front Neurosci. 2020;14:580524 Authors: Bouter Y, Kacprowski T, Rößler F, Jensen LR, Kuss AW, Bayer TA Abstract The transcriptome of non-coding RNA (ncRNA) species is increasingly focused in Alzheimer's disease (AD) research. NcRNAs comprise, among others, transfer RNAs, long non-coding RNAs and microRNAs (miRs), each with...
Tue Oct 06, 2020 13:49
Superoxide and Non-ionotropic Signaling in Neuronal Excitotoxicity. Front Neurosci. 2020;4:861 Authors: Wang J, Swanson RA Abstract Excitotoxicity is classically attributed to Ca2+ influx through NMDA receptors (NMDAr), leading to production of nitric oxide by neuronal nitric oxide synthase and superoxide by mitochondria, which react to form highly cytotoxic peroxynitrite. More recent observations warrant revision of the classic view and help...
Tue Oct 06, 2020 13:49
Related Articles Estimating disease prevalence from drug utilization data using the Random Forest algorithm. Eur J Public Health. 2019 Aug 01;29(4):615-621 Authors: Slobbe LCJ, Füssenich K, Wong A, Boshuizen HC, Nielen MMJ, Polder JJ, Feenstra TL, van Oers HAM Abstract BACKGROUND: Aggregated claims data on medication are often used as a proxy for the prevalence of diseases, especially chronic diseases. However, linkage between medication and...
Tue Oct 06, 2020 13:55
Related Articles Histone deacetylase inhibitors restore normal hippocampal synaptic plasticity and seizure threshold in a mouse model of Tuberous Sclerosis Complex. Sci Rep. 2019 03 27;9(1):5266 Authors: Basu T, O'Riordan KJ, Schoenike BA, Khan NN, Wallace EP, Rodriguez G, Maganti RK, Roopra A Abstract Abnormal synaptic plasticity has been implicated in several neurological disorders including epilepsy, dementia and Autism Spectrum Disorder...
Tue Oct 06, 2020 13:55
Related Articles Predictive Model for Gastrostomy Placement in Adolescents With Developmental Disabilities and Cerebral Palsy. Nutr Clin Pract. 2020 Feb;35(1):149-156 Authors: Bertoncelli CM, Altamura P, Vieira ER, Bertoncelli D, Latalski M, Berthet S, Solla F Abstract BACKGROUND: Factors associated with gastrostomy placement in adolescents with developmental disabilities (DDs) and cerebral palsy (CP) are poorly investigated. We aimed to develop...
Tue Oct 06, 2020 13:55
Related Articles Further Delineation of Pyridoxine-Responsive Pyridoxine Phosphate Oxidase Deficiency Epilepsy: Report of a New Case and Review of the Literature With Genotype-Phenotype Correlation. J Child Neurol. 2019 12;34(14):937-943 Authors: Lugli L, Bariola MC, Ori L, Lucaccioni L, Berardi A, Ferrari F Abstract In recent years, the clinical spectrum of pyridoxine phosphate oxidase (PNPO) deficiency has broadened. There are a growing number...
Tue Oct 06, 2020 13:55
Related Articles Disparities in Pediatric Epilepsy Remission Are Associated With Race and Ethnicity. J Child Neurol. 2019 12;34(14):928-936 Authors: Gregerson CHY, Bakian AV, Wilkes J, Knighton AJ, Nkoy F, Sweney M, Filloux FM, Bonkowsky JL Abstract OBJECTIVE: The purpose of our study was to assess whether race/ethnicity was associated with seizure remission in pediatric epilepsy. METHODS: This was a retrospective population-based...
Tue Oct 06, 2020 13:55
Related Articles Calcifying pseudoneoplasm of the neuroaxis presenting with refractory seizures: Case report and literature review. J Clin Neurosci. 2020 Aug;78:439-443 Authors: Vallejo FA, Chen SH, Bano G, Gultekin S, Morcos J Abstract Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare benign lesions that can arise anywhere within the central nervous system. The etiology of these lesions remains unknown and diagnosis is made on pathohistological...
Tue Oct 06, 2020 13:55
Development and Validation of CRISPR Activator Systems for Overexpression of CB1 Receptors in Neurons. Front Mol Neurosci. 2020;13:168 Authors: Di Maria V, Moindrot M, Ryde M, Bono A, Quintino L, Ledri M Abstract Gene therapy approaches using viral vectors for the overexpression of target genes have been for several years the focus of gene therapy research against neurological disorders. These approaches deliver robust expression of therapeutic...
Tue Oct 06, 2020 13:55
Interleukin 4 Affects Epilepsy by Regulating Glial Cells: Potential and Possible Mechanism. Front Mol Neurosci. 2020;13:554547 Authors: Chen L, Zhu L, Lu D, Wu Z, Han Y, Xu P, Chang L, Wu Q Abstract Epilepsy is a chronic brain dysfunction induced by an abnormal neuronal discharge that is caused by complicated psychopathologies. Recently, accumulating studies have revealed a close relationship between inflammation and epilepsy. Specifically,...
Tue Oct 06, 2020 13:55
A Novel Kv7.3 Variant in the Voltage-Sensing S4 Segment in a Family With Benign Neonatal Epilepsy: Functional Characterization and in vitro Rescue by β-Hydroxybutyrate. Front Physiol. 2020;11:1040 Authors: Miceli F, Carotenuto L, Barrese V, Soldovieri MV, Heinzen EL, Mandel AM, Lippa N, Bier L, Goldstein DB, Cooper EC, Cilio MR, Taglialatela M, Sands TT Abstract Pathogenic variants in KCNQ2 and KCNQ3, paralogous genes encoding Kv7.2 and Kv7.3...
Tue Oct 06, 2020 13:55
Are Variants Causing Cardiac Arrhythmia Risk Factors in Sudden Unexpected Death in Epilepsy? Front Neurol. 2020;11:925 Authors: Bleakley LE, Soh MS, Bagnall RD, Sadleir LG, Gooley S, Semsarian C, Scheffer IE, Berkovic SF, Reid CA Abstract Sudden unexpected death in epilepsy (SUDEP) is the most common cause of premature mortality in individuals with epilepsy. Acute and adaptive changes in heart rhythm in epilepsy implicate cardiac dysfunction...
Tue Oct 06, 2020 13:55
Astrocyte Glutamate Uptake and Signaling as Novel Targets for Antiepileptogenic Therapy. Front Neurol. 2020;11:1006 Authors: Peterson AR, Binder DK Abstract Astrocytes regulate and respond to extracellular glutamate levels in the central nervous system (CNS) via the Na+-dependent glutamate transporters glutamate transporter-1 (GLT-1) and glutamate aspartate transporter (GLAST) and the metabotropic glutamate receptors (mGluR) 3 and mGluR5. Both...
Tue Oct 06, 2020 13:55
ALG13 participates in epileptogenesis via regulation of GABAA receptors in mouse models. Cell Death Discov. 2020;6:87 Authors: Huo J, Ren S, Gao P, Wan D, Rong S, Li X, Liu S, Xu S, Sun K, Guo B, Wang P, Yu B, Wu J, Wang F, Sun T Abstract ALG13 (asparagine-linked glycosylation 13) plays crucial roles in the process of N-linked glycosylation. Mutations of the ALG13 gene underlie congenital disorders of glycosylation type I (CDG-I), a rare human...
Tue Oct 06, 2020 13:55
Distinguishing Epileptiform Discharges From Normal Electroencephalograms Using Scale-Dependent Lyapunov Exponent. Front Bioeng Biotechnol. 2020;8:1006 Authors: Li Q, Gao J, Huang Q, Wu Y, Xu B Abstract Epileptiform discharges are of fundamental importance in understanding the physiology of epilepsy. To aid in the clinical diagnosis, classification, prognosis, and treatment of epilepsy, it is important to develop automated computer programs...
Tue Oct 06, 2020 13:55
Treatment of psychogenic nonepileptic seizures (PNES) using video telehealth. Epilepsia. 2020 Oct 04;: Authors: LaFrance WC, Ho WLN, Bhatla A, Baird GL, Altalib HH, Godleski L Abstract OBJECTIVE: Previous studies have shown the effectiveness of manual-based treatment for psychogenic nonepileptic seizures (PNES), but access to mental health care still remains a problem, especially for patients living in areas without medical professionals who...
Tue Oct 06, 2020 13:55
Warfarin dose adjustment required after cannabidiol initiation and titration. Am J Health Syst Pharm. 2020 Oct 05;: Authors: Cortopassi J Abstract PURPOSE: A case of a possible interaction between cannabidiol and warfarin is presented along with a brief overview of cytochrome enzymes involved in these drugs' metabolism. SUMMARY: A 46-year-old male taking warfarin for treatment of a deep venous thrombosis was initiated on a Food and...
Tue Oct 06, 2020 13:55
Clinical characteristics of 30 COVID-19 patients with epilepsy: a retrospective study in Wuhan. Int J Infect Dis. 2020 Oct 02;: Authors: Sun M, Ruan X, Li Y, Wang P, Zheng S, Shui G, Li L, Zhang H Abstract OBJECTIVE: This study aims to present clinical characteristics of 30 hospitalized cases with epileptic seizure and coronavirus disease 2019(COVID-19). METHODS: This is a retrospective observational research. Clinical data were extracted...
Tue Oct 06, 2020 13:55
Erratum: Editorial: Serafino Zappacosta and the Ceppellini School: A Pioneer Model for Nurturing Education in Immunology. Front Immunol. 2020;11:600832 Authors: Frontiers Production Office Abstract [This corrects the article DOI: 10.3389/fimmu.2020.01524.]. PMID: 33013941 [PubMed]
Tue Oct 06, 2020 13:57
Pembrolizumab plus axitinib combination and the paradigm change in the treatment of advanced renal cell carcinoma. Future Oncol. 2020 Oct 05;: Authors: Spisarová M, Melichar B, Vitásková D, Študentová H Abstract Sequential administration of single targeted agents has been challenged as the dominant treatment paradigm in patients with metastatic renal cell carcinoma by improved outcomes obtained with combination regimens based on immune checkpoint...
Tue Oct 06, 2020 13:59
More than 30 years ago, while I was in training, the best diagnostician I have ever met said — much to my surprise — that some patients who had uncomplicated appendicitis could be successfully treated nonoperatively. He had drawn that conclusion from his practical experiences in the medical corps,…
Mon Oct 05, 2020 03:00
Clinical Significance of the Interleukin 24 mRNA Level in Head and Neck Squamous Cell Carcinoma and Its Subgroups: An In Silico Investigation. J Oncol. 2020;2020:7042025 Authors: Qiu LL, Zhang XG, Chen G, Dang YW, Huang ZG, Li MX, Liang Y, Huang SN, Tang XZ, Chen XX, Wei HY, Wu HY Abstract IL24 mRNA is known to have an apoptotic effect on cancer cells but not on noncancer cells. However, the expression level of the IL24 mRNA in head and neck...
Tue Oct 06, 2020 14:06
Publication date: Available online 5 October 2020Source: Revue des Maladies RespiratoiresAuthor(s): M. Underner, J. Perriot, G. Peiffer, N. Jaafari
Tue Oct 06, 2020 14:07
Publication date: Available online 5 October 2020Source: Sleep MedicineAuthor(s): Jeonghoon Park, Minju Yeo, Jinsu Kim, Sunghun Kim, Seung-Hwan Lee, Sungok Kwon, Dong-Ick Shin, Sangkil Lee, Seo-Young Lee
Tue Oct 06, 2020 14:08
Anticarcinogenic effect of gold nanoparticles synthesized from Albizia lebbeck on HCT-116 colon cancer cell lines. Artif Cells Nanomed Biotechnol. 2020 Dec;48(1):1206-1213 Authors: Malaikolundhan H, Mookkan G, Krishnamoorthi G, Matheswaran N, Alsawalha M, Veeraraghavan VP, Krishna Mohan S, Di A Abstract Colon cancer is one of the major prevailing types of cancer worldwide. It has been the most important public health difficulty. Thus,...
Tue Oct 06, 2020 14:12
Arabian Primrose leaf extract mediated synthesis of silver nanoparticles: their industrial and biomedical applications. Artif Cells Nanomed Biotechnol. 2020 Dec;48(1):1259-1271 Authors: Nindawat S, Agrawal V Abstract The present study encompasses green synthesis of silver nanoparticles (AgNPs) using aqueous leaf extract of Arabian Primrose within 6 min of reaction at 60 °C, pH 7 and their characterisation using physico-chemical analytical...
Tue Oct 06, 2020 14:12
[Cervical plexus block as an alternative anesthetic approach for type I thyroplasty: a case report].
[Cervical plexus block as an alternative anesthetic approach for type I thyroplasty: a case report]. Rev Bras Anestesiol. 2020 Sep 07;: Authors: Abi Lutfallah A, Jabbour K, Gergess A, Hayeck G, Matar N, Madi-Jebara S Abstract BACKGROUND: The role of type I thyroplasty (TIP) is well established as the treatment for glottal insufficiency due to vocal fold paralysis, but the ideal anesthetic management for this procedure is still largely debated....
Tue Oct 06, 2020 14:14
Role of Inhaled Corticosteroids for Asthma Exacerbation in Children: An Updated Meta-Analysis. J Emerg Trauma Shock. 2020 Apr-Jun;13(2):161-166 Authors: Sawanyawisuth K, Chattakul P, Khamsai S, Boonsawat W, Ladla A, Chotmongkol V, Limpawattana P, Chindaprasirt J, Senthong V, Phitsanuwong C, Sawanyawisuth K Abstract Background: Several studies showed that inhaled corticosteroids (ICS) may be a potential treatment in acute asthma exacerbation...
Tue Oct 06, 2020 14:14
HIF-1α as a Mediator of Insulin Resistance, T2DM, and Its Complications: Potential Links With Obstructive Sleep Apnea. Front Physiol. 2020;11:1035 Authors: Gabryelska A, Karuga FF, Szmyd B, Białasiewicz P Abstract Obstructive sleep apnea syndrome (OSA) is described as an independent risk factor for the onset and progression of type 2 diabetes (T2DM), as well as for insulin resistance (IR). The mechanisms underlying these processes remain unclear....
Tue Oct 06, 2020 14:14
Analysis of Clinical Characteristics and Polysomnography Indicators of Obstructive Sleep Apnea-Hypopnea Syndrome Patients Based on Sleep Perception Types. Front Neurol. 2020;11:988 Authors: Liu Y, Tan H, Yu Y, Zeng Y, Xiao L Abstract Purpose: The aim of this study was to explore the clinical characteristics of different sleep perception types of obstructive sleep apnea-hypopnea syndrome (OSAHS) patients and to analyze the correlation between...
Tue Oct 06, 2020 14:14
Clinical and imaging outcomes after intermediate- or high-risk pulmonary embolus. Pulm Circ. 2020 Jul-Sep;10(3):2045894020952019 Authors: Lachant D, Bach C, Wilson B, Chengazi V, Goldman B, Lachant N, Pietropaoli A, Cameron S, James White R Abstract Long-term outcomes after acute pulmonary embolism vary from complete resolution to chronic thromboembolic pulmonary hypertension (CTEPH). Guidelines after acute pulmonary embolism are generally...
Tue Oct 06, 2020 14:14
Obstructive sleep apnea in obese minipigs. J Transl Sci. 2020 Oct;6(5): Authors: Deng MZ, Abdelfattah MY, Baldwin MC, Weaver EM, Liu ZJ Abstract Objective: Obesity has reached epidemic proportions and is a strong risk factor for obstructive sleep apnea (OSA). However, the underlying mechanisms are poorly understood and current treatment strategies for OSA and obesity have critical limitations. Thus, establishment of an obesity-related large...
Tue Oct 06, 2020 14:14
Are symptoms of obstructive sleep apnoea related to good continuous positive airway pressure compliance? ERJ Open Res. 2020 Jul;6(3): Authors: Kaewkes C, Sawanyawisuth K, Sawunyavisuth B Abstract Obstructive sleep apnoea (OSA) is a common disease that can be treated with continuous positive airway pressure (CPAP). CPAP tolerance may be associated with its compliance. Even though there are several predictors for good CPAP compliance, there are...
Tue Oct 06, 2020 14:14
Suture pattern does not influence outcomes of endoscopic sleeve gastroplasty in obese patients. Endosc Int Open. 2020 Oct;8(10):E1349-E1358 Authors: Espinet-Coll E, Nebreda-Durán J, Galvao-Neto M, Bautista-Altamirano C, Diaz-Galán P, Gómez-Valero JA, Vila-Lolo C, Guirola-Puche MA, Fernández-Huélamo A, Bargalló-Carulla D, Juan-Creix Comamala A Abstract Background and study aims ESG is an effective and safe medium-term procedure for obesity...
Tue Oct 06, 2020 14:14
Associations of Self-reported Obstructive Sleep Apnea with Total and Site-specific Cancer Risk in Older Women: A Prospective Study. Sleep. 2020 Oct 05;: Authors: Huang T, Lin BM, Stampfer MJ, Schernhammer ES, Saxena R, Tworoger SS, Redline S Abstract BACKGROUND: Chronic intermittent hypoxia resulting from obstructive sleep apnea (OSA) may activate multiple carcinogenic pathways and lead to cancer development. METHODS: We prospectively...
Tue Oct 06, 2020 14:14
Severe Obstructive Sleep Apnea Is Associated with Higher Brain Amyloid Burden: A Preliminary PET Imaging Study. J Alzheimers Dis. 2020 Sep 27;: Authors: Jackson ML, Cavuoto M, Schembri R, Doré V, Villemagne VL, Barnes M, O'Donoghue FJ, Rowe CC, Robinson SR Abstract BACKGROUND: Obstructive sleep apnea (OSA) has been linked to an increase risk of dementia. Few studies have cross-sectionally examined whether clinically-confirmed OSA is associated...
Tue Oct 06, 2020 14:14
Associations between Sleep Apnoea and Advanced Brain Ageing in a Large-Scale Population Study. Sleep. 2020 Oct 05;: Authors: Weihs A, Frenzel S, Wittfeld K, Obst A, Stubbe B, Habes M, Szentkirályi A, Berger K, Fietze I, Penzel T, Hosten N, Ewert R, Völzke H, Zacharias HU, Grabe HJ Abstract Advanced brain ageing is commonly regarded as a risk factor for neurodegenerative diseases, e.g. Alzheimer's dementia, and it was suggested that sleep disorders...
Tue Oct 06, 2020 14:14
Obstructive sleep apnea in patients with interstitial lung disease: Prevalence and predictive factors. PLoS One. 2020;15(10):e0239963 Authors: Lee JH, Park CS, Song JW Abstract Interstitial lung diseases (ILDs) are chronic, progressive, parenchymal lung diseases with high morbidity and mortality. In recent studies, the prevalence of obstructive sleep apnea (OSA) in patients with ILD has been reported to be high. However, the prevalence and...
Tue Oct 06, 2020 14:14
Airways therapy of obstructive sleep apnea dramatically improves aberrant levels of soluble cytokines involved in autoimmune disease. Clin Immunol. 2020 Oct 02;:108601 Authors: Phillips BG, Wang Y, Ambati S, Ma P, Meagher RB Abstract Obstructive Sleep Apnea (OSA) damages the health of 35% of adult Americans. Disordered sleep results in increased risk of several autoimmune disorders, but the molecular links to autoimmunity are poorly understood....
Tue Oct 06, 2020 14:14
Publication date: Available online 6 October 2020Source: European Journal of Surgical OncologyAuthor(s): James William Butterworth, Piers R. Boshier, Stella Mavroveli, Jan BB. Van Lanschot, Mitsuru Sasako, John V. Reynolds, George B. Hanna
Tue Oct 06, 2020 14:20
Publication date: Available online 5 October 2020Source: Academic RadiologyAuthor(s): Zuhal Bayramoglu, Eda Canıpek, Rana G Comert, Nilufar Gasimli, Ozge Kaba, Mehpare Sarı Yanartaş, Selda Hançerli Torun, Ayper Somer, Sukru Mehmet Erturk
Tue Oct 06, 2020 14:24
Publication date: Available online 6 October 2020Source: Journal of Neuroscience MethodsAuthor(s): Michael X. Cohen
Tue Oct 06, 2020 14:25
Platelet function testing in patients with post-operative tonsillectomy bleeding may be a useful early identifier of inherited platelet function disorders. J Laryngol Otol. 2020 Oct 05;:1-5 Authors: James TW, Thomson BJ, Naumann DN, Stevenson DS Abstract BACKGROUND: Post-tonsillectomy bleeding is the most frequent complication of tonsillectomy. Inherited platelet function disorders have an estimated prevalence of 1 per cent. Any association...
Tue Oct 06, 2020 14:32
Chronic suppurative otitis media in Zimbabwean school children: a cross-sectional study. J Laryngol Otol. 2020 Oct 05;:1-5 Authors: Pedersen CK, Zimani P, Frendø M, Spindler NJ, Chidziva C, von Buchwald C, Jensen RG Abstract OBJECTIVE: Chronic suppurative otitis media is a major cause of disabling childhood hearing loss, especially in low-income countries. Estimates on its prevalence in sub-Saharan Africa range from the lowest to the highest...
Tue Oct 06, 2020 14:32
Publication date: Available online 5 October 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): K. Ramasamy, J. Saniasiaya, N. Abdul Gani
Tue Oct 06, 2020 14:35
Publication date: Available online 5 October 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): C.A. Righini, H. Gil, C. Colombé
Tue Oct 06, 2020 14:35
Majid A Almadi, Abdulrahman M Aljebreen, Nahla Azzam, Faisal BatwaSaudi Journal of Gastroenterology 2020 26(5):285-286
Fri Sep 18, 2020 00:00
Nahla A Azzam, Abdulrahman Aljebreen, Arwa Almuhareb, Majid A AlmadiSaudi Journal of Gastroenterology 2020 26(5):256-262 Background/Aim: Inflammatory bowel disease (IBD) is a chronic disorder affecting patients' health-related quality of life (HRQoL) which adds to their disability. Little is known about the impact of the COVID-19 pandemic on HRQoL of IBD patients. We aimed to evaluate HRQoL in IBD patient's pre- and post-COVID-19 pandemic using the IBD-disk questionnaire and explore associations...
Fri Sep 18, 2020 00:00
Nahla Azzam, Nora Alotaibi, Majid Almadi, Abdulrahman AljebreenSaudi Journal of Gastroenterology 2020 26(5):279-282
Fri Sep 18, 2020 00:00
The psychological impact of COVID-19 pandemic on physicians in Saudi Arabia: A cross-sectional study
Eman Al Sulais, Mahmoud Mosli, Turki AlAmeelSaudi Journal of Gastroenterology 2020 26(5):249-255 Background/Aim: COVID-19 pandemic exposed physicians to extraordinary stress and made them vulnerable to various types of psychological illnesses. The aim of this study was to evaluate the impact that the COVID-19 pandemic had on the psychological well-being of physicians. Materials and Methods: We performed a cross-sectional, survey-based study, targeting physicians in Saudi Arabia during the COVID-19...
Fri Sep 18, 2020 00:00
Mahmoud Mosli, Mansour Alourfi, Amani Alamoudi, Almoutaz Hashim, Omar Saadah, Eman Al Sulais, Turki AlAmeel, Othman Alharbi, Shakir Bakari, Yaser Meeralam, Seigha Alshobai, Majid Alsahafi, Hani Jawa, Yousif QariSaudi Journal of Gastroenterology 2020 26(5):263-271 Background/Aims: The coronavirus (COVID-19) pandemic has caused significant disruption to patients with chronic illnesses. We explored the emotional state, perception, and concerns of Saudi patients with inflammatory bowel disease (IBD)...
Fri Sep 18, 2020 00:00
Majid A Almadi, Abdulrahman M Aljebreen, Nahla Azzam, Nuha Alammar, Emad S Aljahdli, Fahad I Alsohaibani, Resheed Alkhiari, Abdulaziz O Almasoud, Mohammad S Al Beshir, Suliman Alshankiti, Ahmad W Alharbi, Mohammed Alkhathami, Faisal BatwaSaudi Journal of Gastroenterology 2020 26(5):240-248 With the global pandemic due to coronavirus disease 2019 (COVID-19), there has been a significant strain on healthcare facilities. The infectivity rate, as well as the rate of healthcare workers who have fallen...
Fri Sep 18, 2020 00:00
Ahmad S Almalki, Mohammed Khan, Turki AlAmeelSaudi Journal of Gastroenterology 2020 26(5):283-284
Fri Sep 18, 2020 00:00
Bandar Al-Judaibi, Reem Almaghrabi, Mohammed Alghamdi, Waleed K Al-Hamoudi, Mohammed AlQahtani, Faisal Abaalkhail, Mohammed Shagrani, Faisal M SanaiSaudi Journal of Gastroenterology 2020 26(5):233-239 The World Health Organization (WHO), on March 11th 2020, upgraded the status of the novel coronavirus disease (COVID-19) from epidemic to pandemic. Over two million individuals have been infected with SARS-CoV-2, the virus causing COVID-19, and as of April, 14th 2020, there were over 5000 confirmed...
Fri Sep 18, 2020 00:00
Eric M Yoshida, Trana Hussaini, Majid AlsahafiSaudi Journal of Gastroenterology 2020 26(5):223-225
Fri Sep 18, 2020 00:00
Janice Cheong, Nichoals Bartell, Thoetchai Peeraphatdit, Mahmoud Mosli, Bandar Al-JudaibiSaudi Journal of Gastroenterology 2020 26(5):226-232 The novel coronavirus 2 (SARS-CoV-2) has spread worldwide. While patients typically present with fever and symptoms of a respiratory illness, patients have also presented with gastrointestinal symptoms such as diarrhea, vomiting and abdominal pain. In addition, some patients were reported to have liver injury. In this article, we review gastrointestinal and...
Fri Sep 18, 2020 00:00
Tao Li, Ying Guo, Xianghua Zhuang, Laigang Huang, Xingqian Zhang, Fengtao Wei, Baohua YangSaudi Journal of Gastroenterology 2020 26(5):272-278 Background/Aims: We aimed to evaluate the distribution of abnormal liver-related biomarkers in patients with coronavirus disease (COVID-19) and explore the prognostic value of elevated liver enzymes and abnormal liver synthetic capacity with regards to patient mortality. Patients and Methods: This retrospective observational study included 80 laboratory-confirmed...
Fri Sep 18, 2020 00:00
80 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/10/06PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Oct 06, 2020 13:36
80 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/10/06PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Oct 06, 2020 14:36
New England Journal of Medicine, Ahead of Print.
Mon Oct 05, 2020 06:00
New England Journal of Medicine, Ahead of Print.
Mon Oct 05, 2020 06:00
ROC Analysis Cut-off Points of Hellenic Voice Handicap Index for Neurogenic Voice Disorders Patients: an Exploratory Study. J Voice. 2020 Oct 01;: Authors: Tafiadis D, Helidoni ME, Chronopoulos SK, Kosma EI, Alexandropoulou A, Velegrakis S, Konitsiotis S, Ziavra N Abstract OBJECTIVE: The inclusion of subjective methods for evaluating Voice Disorders is proven an essential factor for diagnosis as these methods include self-reported questionnaires...
Tue Oct 06, 2020 15:00
New methodological approaches to atrial fibrillation drug discovery. Expert Opin Drug Discov. 2020 Oct 05;:1-11 Authors: Wong CK, Tse HF Abstract INTRODUCTION: Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice and rhythm control using pharmacological agents is required in selected patients. Nonetheless, current medication is only modestly efficacious and associated with significant cardiovascular and systemic...
Tue Oct 06, 2020 15:00
Publication date: December 2020Source: Photodiagnosis and Photodynamic Therapy, Volume 32Author(s): Guo-long Zhang, Uma Keyal, Lei Shi, Pei-ru Wang, Ling-lin Zhang, Anil Kumar Bhatta, Yu-hao Wu, Shan Fang, Xiu-li Wang
Tue Oct 06, 2020 15:02
Mutual Antagonism of Hypoxia-Inducible Factor Isoforms in Cardiac, Vascular, and Renal Disorders. JACC Basic Transl Sci. 2020 Sep;5(9):961-968 Authors: Packer M Abstract Hypoxia-inducible factor (HIF)-1α and HIF-2α promote cellular adaptation to acute hypoxia, but during prolonged activation, these isoforms exert mutually antagonistic effects on the redox state and on proinflammatory pathways. Sustained HIF-1α signaling can increase oxidative...
Tue Oct 06, 2020 15:08
Journal of Oral and Maxillofacial Pathology 2020 24(2):407-407
Wed Sep 09, 2020 00:00
Rizwan Hamid, Prenika Sharma, Rayees Ahmad Sheikh, Muzafar BhatJournal of Oral and Maxillofacial Pathology 2020 24(2):332-338 Tuberculosis (TB) is still one of the most life-threatening infectious diseases, resulting in high mortality in adults and is commonly found in developing countries. Lung is primarily affected while extrapulmonary TB is rarely encountered. Oral lesions, although rare, can be seen in both primary and secondary stages of TB. Primary oral TB may present a diagnostic challenge...
Wed Sep 09, 2020 00:00
N Santana, S Mehazabin, K Sangeetha, M KumariJournal of Oral and Maxillofacial Pathology 2020 24(2):405-405 Bone is a dense, semi rigid, porous, calcified connective tissue forming the major portion of the skeleton of most vertebrates. It consists of a dense organic matrix and an inorganic mineral component. Bone remodelling is a complex process by which old bone is continuously replaced by new tissue, which requires interaction between different cell phenotypes and is regulated by a variety...
Wed Sep 09, 2020 00:00
Dinshaw Hormuzdi, Sharad Desai, Sushma Bommanavar, Dipti PatilJournal of Oral and Maxillofacial Pathology 2020 24(2):327-331 Carcinosarcoma, a biphasic malignant mixed tumor, is an extremely rare neoplasm with >1% incidence. This aggressive malignancy is characterized by the presence of two components admixed with each other, i.e., the epithelial component and the mesenchymal component arising from a monoclonal/multiclonal origin or de novo. Most patients usually present between 60 and 65...
Wed Sep 09, 2020 00:00
Ashwini Deshpande, Prashant Gupta, A Vikram Simha Reddy, GV Ramachandra ReddyJournal of Oral and Maxillofacial Pathology 2020 24(2):404-404 Developing countries such as India face an intense situation with communicable diseases such as tuberculosis (TB). It is an inflammatory infectious granulomatous disease commonly affecting the lungs. Extrapulmonary TB presentations have been documented, with the orofacial region also being involved. TB usually presents as an ulcer in the oral cavity with...
Wed Sep 09, 2020 00:00
Sasidhar Singaraju, Shubham Patel, Ashish Sharma, Medhini SingarajuJournal of Oral and Maxillofacial Pathology 2020 24(2):322-326 Lymphomas are solid tumors of the immune system and include 14% of all head and neck malignancies. Non-Hodgkin lymphomas (NHLs) are a heterogeneous group of lymphoproliferative disorders originating in B-, T-, or natural killer T-cells. They have a wide range of histological appearances and clinical features at presentation, which can make diagnosis difficult. A 58-year-old...
Wed Sep 09, 2020 00:00
K Nivethitha, Amitha Ramesh, Avaneendra Talwar, Nina ShenoyJournal of Oral and Maxillofacial Pathology 2020 24(2):403-403 In the modern world, men and women are very much concerned about their esthetic appearance. The gingival perspective of esthetics is more often concerned with the soft tissue envelope surrounding the teeth. Gingival enlargement/overgrowth is numerous in nature and often poses a clinical challenge by altering the function, resulting in poor oral health of an individual. Tacrolimus,...
Wed Sep 09, 2020 00:00
Shikha Saxena, Krishna Sireesha Sundaragiri, Akshay Bhargava, Bharat SankhlaJournal of Oral and Maxillofacial Pathology 2020 24(2):315-321 Nevoid basal-cell carcinoma syndrome (NBCCS) or Gorlin–Goltz syndrome is an autosomal dominant-inherited condition that exhibits high penetrance and variable expressivity; however, this disorder can arise spontaneously. In 1960, Gorlin and Goltz described the syndrome as a condition, comprising the principle triad of multiple basal cell carcinoma, odontogenic...
Wed Sep 09, 2020 00:00
Rennan Luiz Oliveira Dos Santos, Jefferson Rocha Tenorio, Ligia Gonzaga Fernandes, Ana Isabel Moreira Ribeiro, Sabrina Araujo Pinho Costa, Marilia Trierveiler, Celso Augusto Lemos, Norberto Nobou SugayaJournal of Oral and Maxillofacial Pathology 2020 24(2):402-402 Leishmaniasis is a chronic inflammatory disease caused by several species of the parasite Leishmania that is transmitted by insects of the genus Phlebotomus spp. or Lutzomyia spp. This disease can affect skin, mucous membranes and viscera...
Wed Sep 09, 2020 00:00
Daffney Mano Doss, Madhava Nirmal, Veeravarmal , R Saravanan, A VenkateshJournal of Oral and Maxillofacial Pathology 2020 24(2):308-314 Aim: The aim of the present study is to analyze the role of GLUT-1 in detection of early alterations occurring in oral leukoplakia. This study was to evaluate the expression of GLUT-1 in normal oral epithelium, the expression of GLUT-1 levels in the tissue samples of oral leukoplakia and to statistically compare the expression of GLUT-1 in normal epithelium and...
Wed Sep 09, 2020 00:00
Esha SinghJournal of Oral and Maxillofacial Pathology 2020 24(2):401-401 Context: The diagnosis and grading of epithelial dysplasia is based on a combination of architectural and cytological changes. A gradual increase in quantitative DNA aberrations has been found to correlate with increasing degree of dysplasia in oral mucous membranes. Aims: The aim of this study is to assess nuclear parameters in potentially malignant and malignant lesions of the oral cavity and to assess cytomorphometric...
Wed Sep 09, 2020 00:00
J Gowthami, N Gururaj, V Mahalakshmi, R Sathya, TR Sabarinath, Daffney Mano DossJournal of Oral and Maxillofacial Pathology 2020 24(2):293-307 Background: Epithelial neoplasm is an important global health-care problem, with high morbidity and mortality rates. Early diagnosis and appropriate treatment are essential for increased life survival. Prediction of occurrence of malignancy in a disease-free individual by any means will be a great breakthrough for healthy living. Aims and Objectives:...
Wed Sep 09, 2020 00:00
Anand Siddappa Tegginamani, Vanishree Halasagundhi Shivakumar, Thomas George Kallarakkal, Siti Mazlipah Ismail, Mannil Thomas Abraham, Ahmad Termizi Bin ZamzuriJournal of Oral and Maxillofacial Pathology 2020 24(2):400-400 Background: Oral potentially malignant disorders have a risk for malignant transformation but are difficult to reliably identify and predict which patients are at the risk for malignant transformation. OCT4 has been hypothesized to play a key oncogenic driver in a variety of...
Wed Sep 09, 2020 00:00
Hyandavi Balla, Divya Uppala, Sumit Majumdar, Sreekanth Kotina, Sravya Kodati, Madhurya NamanaJournal of Oral and Maxillofacial Pathology 2020 24(2):285-292 Background: The Immunomorphological patterns of Lymph Nodes indirectly assess the host immune response facing a malignant tumor. These patterns also help us predict the susceptibility of the patient to Lymph Node Metastasis. Aims and Objectives: To evaluate the Immunomorphological patterns of Lymph Nodes in Oral Squamous Cell Carcinoma...
Wed Sep 09, 2020 00:00
Bharadwaj Bordoloi, Safia Siddiqui, Rohit Jaiswal, Aanchal Tandon, Amol Jain, Rashmi ChaturvediJournal of Oral and Maxillofacial Pathology 2020 24(2):398-399 Background: Solid tumors such as oral squamous cell carcinoma (OSCC) are composed of malignant epithelial cells and the stroma in which these cells are dispersed. As the tumor progresses, the extracellular matrix undergoes dramatic morphological and architectural changes. Special stains make analysis easy and less erroneous by highlighting...
Wed Sep 09, 2020 00:00
S Meera, R Sarangarajan, K RajkumarJournal of Oral and Maxillofacial Pathology 2020 24(2):279-284 Background: 8-isoprostane is one of the stable oxidative stress marker formed by the lipid peroxidation of arachidonic acid. It is present in detectable quantities in all biological fluids. Elevation of 8-Isoprostane has been reported in various neurological, cardiological disorders, and periodontal diseases. Aim: The present study was conducted to estimate and compare the level of 8-isoprostane...
Wed Sep 09, 2020 00:00
Rohit Balwant Moharil, Shubhangi Khandekar, Alka Dive, Ashish BodhadeJournal of Oral and Maxillofacial Pathology 2020 24(2):397-398 Background: Cyclin D1 is derived from PRAD1 or CCND1 gene located on chromosome 11q13 and it acts as a positive regulator of the cell cycle. In normal cells, cyclin D1 promotes progression through the G1 phase of the cell cycle. Over expression of cyclin D1 may lead to shortening of G1 phase, increased cell proliferation and reduced dependency on growth factors....
Wed Sep 09, 2020 00:00
Vidya Kadashetti, Nanda Patil, Kailas Datkhile, Sujata Kanetakar, KM ShivakumarJournal of Oral and Maxillofacial Pathology 2020 24(2):273-278 Background: Odontogenic keratocyst (OKC) is a benign intraosseous lesions (within the jaw bone) of odontogenic origin that account for about 10% of jaw cysts. They are characterized by an aggressive behavior with a relatively high recurrence rate. Early diagnosis and follow-up of the patient with OKC is important because the possibility of such patient...
Wed Sep 09, 2020 00:00
Raghavendra Havale, Dhanu G Rao, Athira Mohan Latha, Manasa Nagaraj, Namira Mohammad Karobari, Namratha TharayJournal of Oral and Maxillofacial Pathology 2020 24(2):389-394 Background: Age plays an important role in personal identification, treatment planning, forensic dentistry, and legal issues. It is one of the key identification tools for distinguishing one person from another and one population from another. An intraoral radiographic technique for age estimation is an easier approach. The...
Wed Sep 09, 2020 00:00
Sneha Singh, Prem Singh, Ridhima Auplish, Shiv Pankaj Khanna, Karan Verma, Sukhpreet Kaur AulakhJournal of Oral and Maxillofacial Pathology 2020 24(2):266-272 Background: Fine-needle aspiration cytology (FNAC) is a sensitive technique for diagnosing salivary gland pathologies. Milan system of reporting salivary gland cytopathology (MSRSGC) is an evidence-based system of reporting which has been introduced to improve reporting and communication between cytopathologist and clinician by introducing...
Wed Sep 09, 2020 00:00
Rizwan M Sanadi, Revati S DeshmukhJournal of Oral and Maxillofacial Pathology 2020 24(2):374-382 Vitamin C, also known as ascorbic acid, is used as a treatment modality in depigmentation of hyperpigmented spots on the skin and gingiva. This systematic review discusses the studies conducted to assess the effect of Vitamin C on melanin pigmentation. The primary objective was to evaluate the effect of Vitamin C on melanin pigmentation. The secondary objective was to analyze the effect of Vitamin...
Wed Sep 09, 2020 00:00
Anil V Ankola, Vaibhav Kumar, Simran Thakur, Richa Singhal, T Smitha, Roopali SankeshwariJournal of Oral and Maxillofacial Pathology 2020 24(2):258-265 Background and Objectives: The perpetual search is on to find botanical complementary adjuncts to the conventional therapies used that is not only cost-effective but also reduces side effects associated with conventional synthetic drugs that are available in the market. The aim of this study was to assess the in vitro anticancer efficacy of hydroalcoholic...
Wed Sep 09, 2020 00:00
Priya Nimish Deo, Revati DeshmukhJournal of Oral and Maxillofacial Pathology 2020 24(2):361-367 Oral squamous cell carcinoma is one of the most common malignancies and is the leading cause of morbidity and mortality. The known risk factors for oral cancer are tobacco, alcohol consumption and betel quid chewing. Nutritional deficiencies and certain microorganisms are also associated with oral cancer. Oral cavity is a host to numerous microorganisms, majority of which are bacterial communities...
Wed Sep 09, 2020 00:00
Preeti Ingalagi, Vijayalakshmi Kotrashetti, Kishore Bhat, Manohar KugajiJournal of Oral and Maxillofacial Pathology 2020 24(2):251-257 Introduction: Periodontitis is a chronic destructive inflammatory disease of the oral cavity. The main causative agent is presence of biofilm formed due to different micro-organisms. Among different micro- organisms “red complex” bacteria is known to be the main causative agent in progression of periodontitis. Porphyromonas gingivalis out of the red the complex...
Wed Sep 09, 2020 00:00
Jayanth Kumar Vadivel, Devaraj Ezhilarasan, Meera Govindarajan, Elangovan SomasundaramJournal of Oral and Maxillofacial Pathology 2020 24(2):344-351 Lichen planus is a chronic inflammatory condition affecting the skin and mucosa. The etiology is unknown but the pathogenesis appears to be an immune-mediated reaction. The mainstay drugs used in the treatment are immunomodulators. The aim of this paper is to report on the therapeutic effectiveness of the alternate medications used in the management...
Wed Sep 09, 2020 00:00
R Suma Kalyani, Vandana RaghunathJournal of Oral and Maxillofacial Pathology 2020 24(2):245-250 Background: Adiponectin, an adipocytokine, plays an important role in the development of Type 2 Diabetes Mellitus (T2DM) in obese and cardiovascular disease patients, with few studies having observed low plasma concentrations. Persistent low-grade inflammation, an important feature in T2DM and obesity, bears an indirect influence on insulin resistance and insulin secretion and is reflected by increased...
Wed Sep 09, 2020 00:00
T SmithaJournal of Oral and Maxillofacial Pathology 2020 24(2):191-192
Wed Sep 09, 2020 00:00
Reshma Venugopal, Radhika Manoj Bavle, Sudhakara Muniswamappa, Soumya Makarla, Sreelatha S Hosthor, Punith ShettyJournal of Oral and Maxillofacial Pathology 2020 24(2):237-244 Background: The association between potentially premalignant oral epithelial lesions (PPOEL), oral squamous cell carcinoma and its higher incidence in South-East Asian population due to the use of arecanut, pan, slaked lime and tobacco is well known. The study was carried out in urban and rural population of Bengaluru,...
Wed Sep 09, 2020 00:00
DB Nandini, Roopa S Rao, BS Deepak, Praveen B ReddyJournal of Oral and Maxillofacial Pathology 2020 24(2):405-405 Isothicyanates present in cruciferous vegetables are known to exhibit chemoprevention by various mechanisms. Presently, there is growing evidence that a phytochemical compound known as sulforaphane in these green leafy vegetables is found to be effective in preventing and treating various cancers such as prostate cancer, breast cancer, colon cancer, skin, urinary bladder and oral...
Wed Sep 09, 2020 00:00
Kiran B Jadhav, Vandana Shah, Ghansham Parmar, Nirali Chauhan, Naveen Shah, Nidhi GuptaJournal of Oral and Maxillofacial Pathology 2020 24(2):230-236 Background: In case of oral squamous cell carcinoma (OSCC) most patients die within first 2 years due to metastasis. To overcome the limitations and drawbacks of the present available methods of assessment of lymph nodes metastasis, the search for alternative method is needed. Aim: The aim of the study is to evaluate the sensitivity, specificity...
Wed Sep 09, 2020 00:00
Ramakant S Nayak, S Rakendu, Vijayalakshmi S Kotrashetti, Ranganath NayakJournal of Oral and Maxillofacial Pathology 2020 24(2):403-403 First bite syndrome (FBS) is a condition that classically presents as severe pain in the preauricular region, initiated on the first bite of a meal. In most of the cases reported, it is associated with a history of upper neck surgery or tumor of the parotid salivary gland or parapharyngeal space (PPS). Some propose that FBS arises due to damage to the cervical...
Wed Sep 09, 2020 00:00
Sudip InduJournal of Oral and Maxillofacial Pathology 2020 24(2):227-229
Wed Sep 09, 2020 00:00
Secil Cubuk, Sina Uckan, Handan Ozdemir, Zeynep Firdevs Taslica, Didem BacanliJournal of Oral and Maxillofacial Pathology 2020 24(2):400-401 Aims: The aim of this study to investigate the efficiency of propranolol on occurrence and development of 4-nitroquinoline 1-oxide (4NQO)-induced squamous cell carcinogenesis of the tongue in rats. Subjects and Methods: The sample was composed of 27 male Sprague Dawley rats that received 50 ppm 4NQO for 20 weeks in drinking water. Group 1 (n = 9) was...
Wed Sep 09, 2020 00:00
R Heera, R RajeevJournal of Oral and Maxillofacial Pathology 2020 24(2):222-226 The success of Kerala's war against COVID-19 has three factors to thank: strong public health system, clear risk communication and community participation. The state's early preparedness, focused health-care interventions led by the public health system, effective lockdown measures assisted by law enforcement agencies, special economic package well in advance, timely assistance for migrant laborers, decentralized...
Wed Sep 09, 2020 00:00
Ulka Idate, Kishore Bhat, Vijayalakshmi Kotrashetti, Manohar Kugaji, Vijay KumbarJournal of Oral and Maxillofacial Pathology 2020 24(2):397-398 Introduction: Capnocytophaga species are recognized as part of human oral microbiota and implicated as periodontal pathogens associated with various periodontal diseases. The three original Capnocytophaga species - Capnocytophaga ochracea, Capnocytophaga sputigena and Capnocytophaga gingivalis were initially isolated from periodontitis in adults, but...
Wed Sep 09, 2020 00:00
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