Abstract Objectives To identify predictorsofacceptable hearing at five‐weeks, six‐ and 12 months in children with bilateral Otitis Media with Effusion (OME). Design and setting Secondary analysis of OSTRICH data, conducted in hospital Ear, Nose and Throat (ENT) and paediatric audiology andaudiovestibular medicine departments across Wales and England. Participants The OSTRICH study included 389 children aged two to eight years with bilateral hearing loss attributable toOME for at least...
Sun Oct 04, 2020 11:11
Publication date: December 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 139Author(s): Shradha Sharma, Mat Daniel
Sun Oct 04, 2020 18:40
Publication date: December 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 139Author(s): Tonya Lee, Sharon Wulfovich, Ellen Kettler, Javan Nation
Sun Oct 04, 2020 18:40
Publication date: December 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 139Author(s): Avinash Shekhar Jaiswal, Rakesh Kumar, Alok Thakar, Rajeev Kumar, Hitesh Verma, Ashu Seith Bhalla, Arvind Kumar Kairo, Aanchal Kakkar, Suresh Chandra Sharma, Pirabu Sakthivel
Sun Oct 04, 2020 18:40
Publication date: December 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 139Author(s): Carlos Fabián Martínez- Cruz, Mayra Norma Ramírez-Vargas, Patricia García-Alonso Themann
Sun Oct 04, 2020 18:40
Publication date: Available online 3 October 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Arvind Chandrakantan, Deepak Mehta, Adam C. Adler
Sun Oct 04, 2020 18:40
Publication date: Available online 3 October 2020Source: Auris Nasus LarynxAuthor(s): Daisuke Nishikawa, Yoshiro Wada, Tomoyuki Shiozaki, Masayuki Shugyo, Taeko Ito, Ichiro Ota, Tadashi Kitahara
Sun Oct 04, 2020 18:04
Platelet-rich fibrin: an autologous biomaterial for healing assistance of pharyngeal repair in total laryngectomy. Eur Arch Otorhinolaryngol. 2020 Oct 03;: Authors: Eid AM, Ebada HA, El-Fattah AMA, Tawfik A Abstract OBJECTIVES: The aim of this study was to evaluate the potential role of platelet-rich fibrin (PRF) application on the pharyngeal repair on decreasing the incidence of pharyngocutaneous fistula (PCF) after total laryngectomy. ...
Sun Oct 04, 2020 15:36
Cancer stem cell markers in adenocarcinoma of the salivary glands - reliable prognostic markers? Eur Arch Otorhinolaryngol. 2020 Oct 03;: Authors: Spiegel JL, Jakob M, Kruizenga M, Freytag S, Bertlich M, Canis M, Ihler F, Haubner F, Kitz J, Weiss BG Abstract PURPOSE: Adenocarcinoma of the salivary glands is of low incidence and a broad range of histopathological subtypes. Cancer stem cell markers (CSC) might serve as novel prognostic parameters....
Sun Oct 04, 2020 15:36
Abstract BackgroundEsophageal benign to borderline tumors are rare entities, and their optimal treatment strategy remains controversial. Surgical robotic enucleation is an option to ptimize their management.MethodsWe prospectively collected data on 7 consecutives esophageal benign to borderline tumors operated robotically over a 4‐years period. Patient baseline characteristics, perioperative outcomes and medium‐term follow‐ups were reviewed and analyzed retrospectively.ResultsTwo patients underwent...
Sat Oct 03, 2020 12:50
Abstract The primary aim of this study was to conduct a systematic review and meta‐analysis to compare complications between outpatient vs inpatient parotidectomy. A systematic review was performed to identify patients undergoing either outpatient or inpatient partodiectomy, in accordance with Preferred Reporting Items for Systematic Reviews and Meta‐Analysis guidelines, using PUBMED, SCOPUS, CINAHL, and the Cochrane library. Risk of bias was assessed using the Newcastle‐Ottawa Scale. Postoperative...
Sat Oct 03, 2020 22:35
Abstract Background Head and neck squamous cell carcinoma (HNSCC) is one of the few malignant tumors that respond well to immunotherapy. We aimed to investigate the immune‐related genes and immune cell infiltration of HNSCC and construct a predictive model for its prognosis. Methods We calculated the stromal/immune scores of patients with HNSCC from The Cancer Genome Atlas using the Estimation of STromal and Immune cells in MAlignant Tumor tissues using Expression data algorithm and investigated...
Sat Oct 03, 2020 22:30
Abstract Recently, increasing attention has been paid to senescence‐associated secretory phenotype (SASP), a phenomenon that senescent cells secrete molecules such as inflammatory cytokines and matrix metalloproteinases (MMPs), due to its noxious effects on the surrounding tissue. Senescent cells in the blood and liver are known to be properly depleted by macrophages. In the dermis, accumulation of senescent cells has been reported and is thought to be involved with skin aging. In this study, to...
Sat Oct 03, 2020 16:59
Abstract Accumulating evidence has highlighted the essential roles of cytokines in itch processing. Although IL‐23 and Th17 cytokines are elevated in inflammatory skin disorders, their role in itch is unknown. Here we investigated the role of IL‐23 and IL‐17A in itch response using an in vitro calcium imaging of mouse dorsal root ganglion (DRG) neurons and an in vivo behavior test. Calcium imaging studies revealed that a few DRG neurons (~5%) responded to either IL‐23 or IL‐17A. Pre‐treatment cells...
Sat Oct 03, 2020 16:49
Abstract Purpose The aim of our study is to evaluate the incidence and characteristics of otolaryngology symptoms in COVID 19 patients. Methods 116 patients with positive PCR test results for COVID-19 and followed up by otolaryngologists at a tertiary referral center/COVID-19 pandemic hospital were questioned in terms of otolaryngology symptoms associated...
Sat Oct 03, 2020 03:00
Objectives/Hypothesis The aims of this study were to evaluate the diagnostic test features of bedside ultrasonography in pediatric patients with nasal trauma and to investigate whether it is a preferable alternative method to conventional radiography (CR). Study Design Cross‐sectional prospective study. Methods This prospective study was conducted from March 1, 2019, through November 1, 2019. Thirty‐one patients under the age of 18 years who had nasal trauma were consecutively included....
Sat Oct 03, 2020 14:32
Objectives/Hypothesis To identify the incidence and nature of positive findings on imaging studies ordered for evaluation of unilateral vocal fold paralysis (UVFP) of unknown etiology, to analyze these findings based on laterality, and to examine the use of the expanded‐field computed tomography (CT) neck protocol in this evaluation. Study Design Retrospective review. Methods A total of 145 patients from 2000 to 2018 with UVFP of unknown etiology were studied. Data on imaging studies...
Sat Oct 03, 2020 14:31
Implantation of a vagus nerve stimulator (VNS) can be an effective treatment for medically refractory seizures. Laryngeal side effects from a VNS can include hoarseness, cough, and shortness of breath. This report highlights a 5‐year‐old female who presented with stridor in the setting of acquired laryngomalacia, global developmental delay, and a VNS device. The case demonstrates that a VNS can exacerbate the symptoms of acquired laryngomalacia and that close monitoring of laryngeal side effects...
Sat Oct 03, 2020 14:16
Objectives/Hypothesis To determine the utility of preoperative penetration‐aspiration scale (PAS) scores and clinical findings on modified barium swallow (MBS) in predicting advancement of diet after interarytenoid injection augmentation (IAIA). Study Design Retrospective review. Methods In this retrospective cohort study, 372 consecutive patients who underwent IAIA for pharyngeal dysphagia between 2009 and 2019 were initially identified. Patients were excluded from the study if they...
Sat Oct 03, 2020 14:16
Objectives Laryngeal amyloidosis (LA) is a rare disease characterized by extracellular protein deposition within the larynx. Treatment is difficult due to the frequently submucosal and multifocal nature of disease. The mainstay of treatment is surgical resection; however, recurrence rates are high. Recently, use of radiotherapy (RT), either alone or postoperatively, for LA has been adapted from the management of extramedullary plasmacytoma and has been shown to provide local disease control. Here,...
Sat Oct 03, 2020 14:05
Objectives To highlight the feasibility and evaluate the outcomes of the transorbital endoscopic approach (TOEA) in the management of frontal sinus cerebrospinal fluid (CSF) leaks. Study design Retrospective case series. Methods The database of patients with frontal sinus CSF leaks managed with TOEA from January 2017 through December 2019 at our institution was reviewed. Two videos of clinical case examples are presented. Results Sixteen patients (10 males, 6 females, mean age...
Sat Oct 03, 2020 13:58
ABSTRACT Objectives To determine the prevalence and associated risk factors of voice disorders in healthcare workers of high‐risk hospital care units during the COVID‐19 pandemic. Study design Cross‐sectional study. Methods Questionnaire survey to healthcare personnel of COVID‐19 high‐risk hospital units was conducted, regarding demographic data, clinical activity, the pattern of usage of personal protective equipment, medical and vocal history, vocal symptoms and Spanish validated...
Fri Oct 02, 2020 20:24
UT Physicians Audiology and UT Physicians Otorhinolaryngology, the outpatient clinics of the Department of Otorhinolaryngology-Head and Neck Surgery at McGovern...
Sat Oct 03, 2020 20:27
Abstract Purpose The aim of this study was to determine whether preoperative depressive symptoms influence health-related quality of life (HRQOL) after middle ear surgery in patients with chronic otitis media (COM). Methods This prospective clinical case study was conducted at a tertiary referral center. All 102 patients who had undergone middle ear surgery...
Sat Oct 03, 2020 03:00
Abstract To evaluate the pattern of sensorineural hearing loss (SNHL) in patients attending ENT OPD in a military setup as well as to compare the incidence of hearing loss in Military Personnel with civilian population. This observational cross sectional comparative study was conducted over a period of April 2018 to July 2019. A total of 300 patients with hearing loss (HL) were included. Demographic characteristics along with laterality of sensorineural hearing impairment were...
Sat Oct 03, 2020 03:00
Publication date: Available online 2 October 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): R. Jankowski, P. Gallet, D.-T. Nguyen, C. Rumeau
Sat Oct 03, 2020 19:06
Publication date: December 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 139Author(s): Joshua A. Stramiello, Amir Mohammadzadeh, Justin Ryan, Matthew T. Brigger
Sat Oct 03, 2020 16:35
Objective: Evaluate a new autologous mushroom-shaped cortical bone partial ossicular replacement prosthesis (MPORP) for cost-effective and sustainable hearing results. Study Design: Prospective study. Setting: Tertiary care center. Patients: Forty-two patients suffering from chronic otitis media with intact superstructure of the stapes and partially or completely eroded incus. Interventions: Group-1 (n = 24) underwent only tympanoplasty with MPORP; group-2 (n = 18) underwent...
Wed Sep 30, 2020 03:00
Abstract Objectives The aim of this study was to evaluate the potential role of platelet-rich fibrin (PRF) application on the pharyngeal repair on decreasing the incidence of pharyngocutaneous fistula (PCF) after total laryngectomy. Methods This randomized controlled clinical trial was conducted on 67 patients with advanced laryngeal carcinoma who underwent...
Sat Oct 03, 2020 03:00
Abstract Objectives Voice rehabilitation after laryngectomy is by tracheo esophageal puncture (TEP) and prosthesis insertion. Secondary TEP is very difficult due to neck fibrosis. Puncture under local anaesthesia with endoscopy guidance is a feasible option. Methods Retrospective review of all laryngectomy patients from March 2009 till March 2019 was...
Sat Oct 03, 2020 03:00
Objective: Evaluate a new autologous mushroom-shaped cortical bone partial ossicular replacement prosthesis (MPORP) for cost-effective and sustainable hearing results. Study Design: Prospective study. Setting: Tertiary care center. Patients: Forty-two patients suffering from chronic otitis media with intact superstructure of the stapes and partially or completely eroded incus. Interventions: Group-1 (n = 24) underwent only tympanoplasty with MPORP; group-2...
Wed Sep 30, 2020 03:00
Abstract Fibrovascular polyps are rare benign epithelial neoplasia of the cervical esophagus. Usually they are large and frequently require a thoracotomy/thoracoscopy. This is a case report of an elderly lady with a large Fibrovascular polyp who had anemia and weight loss due to dysphagia, managed by rendezvous technique.
Sat Oct 03, 2020 03:00
Abstract Background To investigate medication adherence (MA) to Levothyroxine in differentiated thyroid cancer survivors and analyze the related factors for nonadherence. Methods The Medication Adherence Report Scale (MARS), Hospital Anxiety and Depression Scale (HAD), Brief Illness Perception Questionnaire (B‐IPQ), and Beliefs about Medicines Questionnaire (BMQ) were used to assess MA. Results Nonadherence was reported in 77 of 197 patients (39.1%). Socioeconomic status and education...
Fri Oct 02, 2020 21:48
Abstract The tumor immune microenvironment of oral tongue squamous cell carcinoma may be accountable for differences in clinical behavior, particularly between different age groups. We performed RNA expression profiling and evaluated tumor infiltrating lymphocytes (TILs) and their T-cell subsets in order to assess the functional status of oral tongue squamous cell carcinoma tumor microenvironment and detect potentially clinically useful associations. Archival surgical pathology...
Sat Oct 03, 2020 03:00
Abstract Purpose Adenocarcinoma of the salivary glands is of low incidence and a broad range of histopathological subtypes. Cancer stem cell markers (CSC) might serve as novel prognostic parameters. To date, only a few studies examined the expression of CSC in adenocarcinoma of the salivary glands with diverging results. To further investigate the reliability in terms of prognostic value, a histopathological analysis of CSCs on a cohort...
Sat Oct 03, 2020 03:00
ABSTRACT Hair follicles cyclically regenerate throughout adult mammalian life, owing to a resident population of epithelial hair follicle stem cells. Stem cell (SC) activity drives bouts of follicle growth, which are periodically interrupted by follicle regression and rest. These phases and the transitions between them are tightly spatiotemporally coordinated by signaling crosstalk between stem/progenitor cells and the various cell types of the microenvironment, or niche. The dermal papilla (DP)...
Fri Oct 02, 2020 15:59
Publication date: Available online 1 October 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): R. Baudouin, F. Simon
Fri Oct 02, 2020 18:45
Publication date: Available online 1 October 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): L. Le Carboulec, J. De Mestier, M. Boucenna, J.-B. Lecanu
Fri Oct 02, 2020 18:45
Publication date: Available online 1 October 2020Source: Acta Otorrinolaringológica EspañolaAuthor(s): J Alexander Sistiaga Suárez, Fernando López Álvarez, Eduardo Ferrandis Perepérez, Pablo Parente Arias, Pedro Díaz de Cerio Canduela, en representación de la comisión de cabeza y cuello y base de cráneo de la SEORL-CCC
Fri Oct 02, 2020 16:59
Condition: UltrasoundIntervention: Sponsor: Chinese PLA General HospitalNot yet recruiting
Fri Oct 02, 2020 16:26
Topical lignocaine anaesthesia for oropharyngeal sampling for COVID-19. Eur Arch Otorhinolaryngol. 2020 Oct 01;: Authors: Kanodia A, Srigyan D, Sikka K, Choudhary A, Choudekar A, Mittal S, Bhopale SA, Dar L, Thakar A Abstract OBJECTIVES: To ascertain if topical lignocaine application in oropharynx prior to swab sampling to test for COVID-19 improves a patient's comfort and to assess its effect on the swab sample taken to conduct the RT-PCR....
Fri Oct 02, 2020 16:08
Endoscopic stapes surgery outcomes and complication rates: a systematic review. Eur Arch Otorhinolaryngol. 2020 Oct 01;: Authors: Bartel R, Sanz JJ, Clemente I, Simonetti G, Viscacillas G, Palomino L, Asarta I, Lao X Abstract OBJECTIVE: These days, the gold standard procedure for otosclerosis treatment is stapes surgery. The endoscopic approach of the procedure is gaining popularity as endoscopic ear surgery develops across the globe. The main...
Fri Oct 02, 2020 16:08
Prevalence of the prelacrimal recess in maxillary sinus and its medial bony wall dimensions. Eur Arch Otorhinolaryngol. 2020 Oct 01;: Authors: Chen Z, Wang Q, Wang P Abstract OBJECTIVE: To investigate the occurrence rate of the prelacrimal recess (PLR) and its medial bony wall dimensions based on the radiological analysis to help surgeons enhance the understanding of anatomic structures for the endoscopic prelacrimal recess approach. ...
Fri Oct 02, 2020 16:08
Topographic anatomy of the ınternal branch of the superior laryngeal nerve. Eur Arch Otorhinolaryngol. 2020 Oct 01;: Authors: Güven EM, Karacan K, Güven M, Elden H, Özçelik Korkmaz M Abstract PURPOSE: The aim of this study was to investigate the surgical and topographical anatomy of the internal branch of the superior laryngeal nerve (ibSLN) in laryngectomy patients. METHODS: Patients aged 36-90 years old who underwent a total laryngectomy...
Fri Oct 02, 2020 16:08
Multi-parametric arterial spin labeling and diffusion-weighted imaging in differentiation of metastatic from reactive lymph nodes in head and neck squamous cell carcinoma. Eur Arch Otorhinolaryngol. 2020 Sep 30;: Authors: Razek AAKA, Helmy E Abstract PURPOSE: To assess arterial spin labeling (ASL) and diffusion-weighted imaging (DWI) in the differentiation of metastatic from reactive lymph nodes (LNs) in head and neck squamous cell carcinoma...
Fri Oct 02, 2020 16:08
Post-COVID-19 paradoxical vocal fold movement disorder. Eur Arch Otorhinolaryngol. 2020 Sep 30;: Authors: Lechien JR, Circiu MP, Crevier-Buchman L, Hans S PMID: 33000300 [PubMed - as supplied by publisher]
Fri Oct 02, 2020 16:08
Radiation-induced toxicities and outcomes after radiotherapy are independent of patient age in elderly salivary gland cancer patients: results from a matched-pair analysis of a rare disease. Eur Arch Otorhinolaryngol. 2020 Sep 30;: Authors: Rühle A, Rothhaar S, Haehl E, Kalckreuth T, Sprave T, Stoian R, Zamboglou C, Gkika E, Knopf A, Grosu AL, Nicolay NH Abstract PURPOSE: This study analyzed survival and toxicity after (chemo)radiotherapy for...
Fri Oct 02, 2020 16:08
Objectives Squamous cell carcinoma of nasal vestibule and pyramid is rare, thus classification, treatment protocol, and indications for elective neck treatment are still controversial. Nasal reconstruction is challenging, as well, and prosthesis is still used. Study Design Retrospective cohort study. Methods Retrospective review of patients surgically treated from 2010 to 2018 in a single Institution. Advanced tumors were further treated with adjuvant irradiation. Reconstruction strategy...
Fri Oct 02, 2020 15:17
Introduction Chronic rhinosinusitis (CRS) is associated with a significant decrease in general health‐related quality of life (QOL). The EuroQol 5‐dimensional questionnaire measures general health‐related quality of life through a health utility value (EQ‐5D HUV)—based on five domains reflecting mobility, self‐care, activities of daily life, pain/discomfort, and anxiety/depression—and an unbiased visual analog scale (EQ‐5D VAS). We sought to identify characteristics of CRS patients with a high EQ‐5D...
Fri Oct 02, 2020 15:04
Objective To explore the relationship between tumor size and facial nerve outcomes following vestibular schwannoma (VS) resection. Study Design Single institutional retrospective chart review of all adult patients with untreated sporadic VS who underwent surgical resection from 2008 to 2018 with preoperative magnetic resonance imaging (MRI) and 1 year of follow‐up. The primary outcome measure was facial nerve outcome as assessed by the House‐Brackmann facial nerve grading system. Results...
Fri Oct 02, 2020 14:59
Stridor can be a very alarming symptom in children, as it is typically caused by turbulent airflow through a partially obstructed airway, due to an organic cause. An abnormal respiratory sound can induce the suspicion of a life‐threatening clinical condition and requires an immediate diagnostic assessment. The aim of this article is to describe a very peculiar case of loud expiratory stridor, with an abrupt onset and no other associated symptoms, occurring in an 11‐year‐old girl. The stridor sounds...
Fri Oct 02, 2020 14:56
Objectives There is debate among otolaryngologists and other practitioners about whether upper lip tie contributes to difficulty with breastfeeding and whether upper lip tie and ankyloglossia are linked. Our objectives were to evaluate the anatomy of the upper lip (maxillary) frenulum, to determine if the visual anatomy of the upper lip has an effect on breastfeeding, and to determine whether the occurrence of lip tie and tongue tie are correlated. Methods A prospective cohort study of 100...
Fri Oct 02, 2020 14:51
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