Publication date: Available online 3 October 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Wael Mohamed Mohamed, Wael Khedr, Medhat Elsawy
Publication date: Available online 3 October 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Minkyeong Kim, Ah Reum Kim, Jongkyu Park, Ji Sun Kim, Jong Hyeon Ahn, Woong-Yang Park, Nayoung K.D. Kim, Chung Lee, Nam-Soon Kim, Jin Whan Cho, Jinyoung Youn
Publication date: Available online 3 October 2020Source: World NeurosurgeryAuthor(s): Sam Ng, Nozar Aghakhani, Luc Bauchet
Publication date: Available online 3 October 2020Source: World NeurosurgeryAuthor(s): Megh M. Trivedi, Sarah Worley, Alankrita Raghavan, Paramita Das, Pablo F. Recinos, Gene H. Barnett, Varun R. Kshettry
Publication date: Available online 3 October 2020Source: World NeurosurgeryAuthor(s): Stephanie Toscano Kasabkojian, Alexandre Jack Dwan, Maria Paula Maziero, Antonio de Salles, Alessandra Gorgulho, Eurípedes Constantino Miguel, Edoardo Fillipo de Queiroz Vattimo, Antonio Carlos Lopes
Publication date: Available online 3 October 2020Source: Journal of Neuroscience MethodsAuthor(s): Ana Paula de Castro Araujo, Jalles Dantas de Lucena, Davi Drieskens Carvalho de Castro Sá Barreto, Lívia Rodrigues Neves, Karen Cristina Pugliane, Hindiael Aeraf Belchior, Rochele Castelo-Branco, Flávio Freitas Barbosa
Abstract In latitudinal avian migrants, increasing photoperiods induce fat deposition and body mass increase, and subsequent nighttime migratory restlessness in captive birds, but the underlying mechanisms remain poorly understood. We hypothesized that an enhanced hypothalamic neuronal plasticity was associated with the photostimulated spring migration phenotype. We tested this idea in adult migratory redheaded buntings (Emberiza bruniceps), as compared with resident Indian weaverbirds (Ploceus...
Abstract Neonatal stroke is a leading cause of long‐term disability and currently available rehabilitation treatments are insufficient to promote recovery. Activating neural precursor cells (NPCs) in adult rodents, in combination with rehabilitation, can accelerate functional recovery following stroke. Here, we describe a novel method of constraint‐induced movement therapy (CIMT) in a rodent model of neonatal stroke that leads to improved functional outcomes, and asked whether the recovery was correlated...
Abstract Purpose To develop postoperative surveillance protocols that yield efficient detection rates of tumor recurrence or progression using fewer imaging studies and less cost. Method This is a retrospective cohort study of all pediatric craniopharyngioma patients who have been diagnosed and treated at Boston Children’s Hospital (BCH) between 1990...
Publication date: Available online 2 October 2020Source: Journal of Neuroscience MethodsAuthor(s): Bo Hu, Ying Yu, Wen Wang, Guang-Bin Cui
Publication date: Available online 2 October 2020Source: Journal of Neuroscience MethodsAuthor(s): Daniel Saska, Paul Pichler, Chen Qian, Christopher L. Buckley, Leon Lagnado
Publication date: Available online 2 October 2020Source: Journal of Neuroscience MethodsAuthor(s): Julian Madrid, David H. Benninger
Publication date: Available online 2 October 2020Source: Journal of Neuroscience MethodsAuthor(s): Maryam Afzali, Tomasz Pieciak, Sharlene Newman, Eleftherios Garifallidis, Evren Özarslan, Hu Cheng, Derek K Jones
Abstract Snakes have proven to drive early attentional capture due to their evolutionary importance, as reflected by the early posterior negativity (EPN). The EPN snake effect might be partly driven by the proximity of the animal. In this study, by employing full-body (medium shot) and head-focused (close-up) pictures, we investigated whether the relative nearness (proximity) of the animal on the picture affects the snake EPN effect. We presented thirty participants with medium...
Soft tissue density within the foramen magnum, a predictor for surgical intervention in pediatric patients with Chiari malformation type I. J Neurosurg Pediatr. 2020 Oct 02;:1-5 Authors: Fuell W, Elwy R, Harkey T, Carey M, Albert GW Abstract OBJECTIVE: Chiari malformation type I (CMI) is diagnosed as herniation of the cerebellar tonsils by at least 5 mm below the foramen magnum. However, the degree of tonsillar herniation is a poor predictor...
Endoscope-assisted microsurgical resection of intrinsic brainstem epidermoid: technical note and review of the literature. J Neurosurg Pediatr. 2020 Oct 02;:1-7 Authors: Cohen AR, Stone SSD Abstract Intrinsic epidermoid tumors of the brainstem are rare, histologically benign lesions associated with high surgical morbidity and mortality due to their eloquent location. The authors report a child with progressive severe neurological deterioration...
Endoscopic ultrasonic aspiration of an intraparenchymal hematoma in a newborn. J Neurosurg Pediatr. 2020 Oct 02;:1-6 Authors: LoPresti MA, Goethe EA, Bayley JC, Bertot B, Kan PT, Lam S Abstract Neonatal intracerebral hemorrhage is associated with substantial morbidity and mortality. Treatment is largely conservative, though interventions to evacuate intraventricular and intraparenchymal hematomas (IPHs) have been applied. Endoscopic ultrasonic...
Interactions between programmable shunt valves and magnetically controlled growing rods for scoliosis. J Neurosurg Pediatr. 2020 Oct 02;:1-4 Authors: Larrew T, Alshareef M, Murphy RF, Eskandari R, Kosnik Infinger L Abstract OBJECTIVE: Although the advent of magnetic growing rod technology for scoliosis has provided a means to bypass multiple hardware lengthening operations, it is important to be aware that many of these same patients have a...
Effects of intraoperative liposomal bupivacaine on pain control and opioid use after pediatric Chiari I malformation surgery: an initial experience. J Neurosurg Pediatr. 2020 Oct 02;:1-7 Authors: Lu VM, Daniels DJ, Haile DT, Ahn ES Abstract OBJECTIVE: Pediatric Chiari I malformation decompression is a common neurosurgical procedure. Liposomal bupivacaine (LB) is a novel formulation that can have an impact on postoperative recovery for particular...
Publication date: Available online 2 October 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Woo-Young Jo, Hyongmin Oh, Heewon Kim, Hyun-Kyu Yoon, Hyung-Chul Lee, Won-Sang Cho, Jeong-Eun Kim, Hee-Pyoung Park
Abstract Major depressive disorder (MDD) is one of the most severe global health problems with millions of people affected, however the mechanisms underlying this disorder is still poorly understood. Genome‐wide association studies have highlighted a link between the neutral amino acid transporter SLC6A15 and MDD. Additionally, a number of preclinical studies support the function of this transporter in modulating levels of brain neurotransmitters, stress system regulation and behavioral phenotypes...
Abstract The bed nucleus of the stria terminalis (BNST) is a sexually dimorphic, neuropeptide‐rich node of the extended amygdala that has been implicated in responses to stress, drugs of abuse, and natural rewards. Its function is dysregulated in neuropsychiatric disorders that are characterized by stress‐ or drug‐induced alterations in mood, arousal, motivation, and social behavior. However, compared to the BNST’s role in mood, arousal, and motivation, its role in social behavior has remained relatively...
Abstract Purpose Intracranial pressure (ICP) > 20 mmHg is associated with worse outcomes in children. The gold standard for monitoring ICP is invasive, has complications such as bleeding and infection, and may not be available in resource limited areas. Ultrasound of the optic nerve sheath diameter (ONSD) has been studied as a noninvasive way to evaluate for elevated ICP in adults. Its utility in pediatrics remains unclear. ...
Knowledge of the intrinsic variability of radiomic features is essential to the proper interpretation of changes in these features over time. The primary aim of this study was to assess the test-retest repeatability of radiomic features extracted from 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) images of cervical tumors. The impact of different image pre-processing methods was also explored. Methods: Patients with cervical cancer underwent baseline and repeat FDG PET/CT imaging...
Background: Treatment of advanced metastatic castration resistant prostate cancer (mCRPC) after failure of approved therapy options remains challenging. Prostate-specific membrane antigen (PSMA) targeting β- and α-emitters have been introduced with promising response rates. Here, we present the first clinical data for PSMA targeted α-therapy (TAT) using 225Ac-PSMA-I&T. Methods: 18 patients receiving 225Ac-PSMA-I&T have been included in this retrospective analysis. 15/18 had prior second...
The world’s first total-body PET scanner with an axial field-of-view (AFOV) of 194 cm is now in clinical and research use at our institution. The uEXPLORER PET/CT scanner, developed through a collaboration between the University of California, Davis (UC Davis) and United Imaging Healthcare (UIH), is the first commercially available total-body PET scanner. Here we present a detailed physical characterization of the uEXPLORER PET scanner based on NEMA NU-2-2018 along with a new set of measurements...
The presence of lymph node (LN) metastases is an essential prognostic indicator in patients with head and neck squamous cell carcinoma (HNSCC). This study assessed photoacoustic molecular imaging (PAMI) of the anti-epidermal growth factor receptor (EGFR) antibody (panitumumab) conjugated to a near-infrared fluorescent dye, IRDye800CW (panitumumab-IRDye800CW; pan800) for the identification of occult metastatic LNs in patients with HNSCC (n=7). After in vitro photoacoustic imaging characterization...
The purpose of this study was to evaluate the potential of 16α-[18F]-fluoro-17β-estradiol (18F-FES) PET to predict prognosis in patients with endometrial cancer (EC). Methods: A total of 67 patients with the International Federation of Gynecology and Obstetrics (FIGO) stage I–IV endometrial cancer underwent 18F-FES and 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) before treatment. The mean standardized uptake value (SUV) of the primary tumor was compared...
Benign thyroid disorders, especially hyper and hypothyroidism are the most prevalent endocrine disorders. The most common etiologies of hyperthyroidism are autoimmune hyperthyroidism (Graves’ disease, GD), toxic multinodular goiter (TMNG) and toxic thyroid adenoma (TA). Less common etiologies include destructive thyroiditis (e.g., amiodarone-induced thyroid dysfunction), and factitious hyperthyroidism. GD is caused by autoantibodies against the TSH receptor. TMNG and TA are caused by a somatic activating-gain-of-function...
Abstract Positional plagiocephaly is the most common cause of cranial asymmetry. Deformational brachycephaly denotes a head shape characterized by occipital flattening and increased bilateral width, which can also be caused by external deformation of the moldable infant cranium in positional bilateral posterior plagiocephaly. There are reports of craniosynostosis associated with Chiari I malformation (CIM), possibly caused by decreased posterior fossa volume and related to increased...
Abstract Purpose While there are increasing numbers of studies published regarding Chiari I malformation (CM1) in children, most of these focus on surgical indications, technique, and outcomes. Few studies examine the natural history of CM1 once the decision is made to treat a patient conservatively. In this study, we seek to determine the percentage of pediatric patients who undergo surgery for CM1, both after initial consultation...
Publication date: Available online 2 October 2020Source: NeuroImageAuthor(s): Øystein Sørensen, Andreas M. Brandmaier, Dídac Macià, Klaus Ebmeier, Paolo Ghisletta, Rogier A. Kievit, Athanasia M. Mowinckel, Kristine B. Walhovd, Rene Westerhausen, Anders Fjell
Publication date: Available online 1 October 2020Source: NeuroImageAuthor(s): Verónica Mäki-Marttunen, Thomas Espeseth
Publication date: Available online 1 October 2020Source: NeuroImageAuthor(s): Gangyi Feng, Zhenzhong Gan, Fernando Llanos, Danting Meng, Suiping Wang, Patrick C.M. Wong, Bharath Chandrasekaran
Publication date: Available online 1 October 2020Source: NeuroImageAuthor(s): Miguel Dasilva, Alessandra Camassa, Alvaro Navarro-Guzman, Antonio Pazienti, Lorena Perez-Mendez, Gorka Zamora-Lopez, Maurizio Mattia, Maria V. Sanchez-Vives
Publication date: Available online 2 October 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): María Bárbara Eizaguirre, Natalia Ciufia, María Sol Roman, Carlos Martínez Canyazo, Ricardo Alonso, Berenice Silva, Cecilia Pita, Orlando Garcea, Sandra Vanotti
Publication date: Available online 2 October 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Nicole Lorking, Adrian D Wood, Somsak Tiamkao, Allan B Clark, Kannikar Kongbunkiat, Joao H Bettencourt-Silva, Kittisak Sawanyawisuth, Narongrit Kasemsap, Mamas A. Mamas, Phyo K Myint
Publication date: Available online 2 October 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Shivangi Singh, Raghav Govindarajan
Publication date: Available online 2 October 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Sahin Hanalioglu, Gokhan Bozkurt, Ilkay Isikay, Orkhan Mammadkhanli
Publication date: Available online 1 October 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Heng Cai, Liangyu Chen, Nan Zhang, Wei Tang, Fangyu Yang, Zhiqing Li
Publication date: Available online 1 October 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Ehsan Dowlati, Matthew Shashaty, Austin H. Carroll, Gnel Pivazyan, Jessica Briscoe, Nirali Patel, Shima Shahjouie, Amjad N. Anaizi, Patrick G. Jackson, Mani N. Nair
Publication date: Available online 1 October 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Isil Ezgi Eryilmaz, Sevda Erer, Mehmet Zarifoglu, Unal Egeli, Ece Karakus, Beste Yurdacan, Gulsah Cecener, Berrin Tunca, Beril Colakoglu, Ayse Bora Tokcaer, Esen Saka, Meltem Demirkiran, Cenk Akbostanci, Okan Dogu, Hakan Kaleagasi, Gulay Kenangil, Raif Cakmur, Bulent Elibol
Publication date: Available online 1 October 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Yuki Yasutaka, Shinsuke Fujioka, Takayasu Mishima, Hirotomo Shibaguchi, Yoshio Tsuboi, Hidetoshi Kamimura
Publication date: Available online 1 October 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Kang Min Park, Seongho Park, Dong Ah Lee, Ho-Joon Lee, Sung Eun Kim
Publication date: Available online 1 October 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Maher Saqqur, Abdul Salam, Ali Ayyad, Naveed Akhtar, Musab Ali, Adnan Khan, Yahya Imam, Sujatha Joseph, Salman Al Jerdi, Ashfaq Shuaib
Publication date: December 2020Source: Brain Research Bulletin, Volume 165Author(s): Samuel Rawlings, Ryusuke Takechi, Andrew P. Lavender
Publication date: Available online 1 October 2020Source: Brain Research BulletinAuthor(s): Poonam Goswami, Mohd Amir Afjal, Juheb Akhter, Anuradha Mangla, Jasim Khan, Suhel Parvez, Sheikh Raisuddin
Publication date: January 2021Source: World Neurosurgery, Volume 145Author(s): Magalie Cadieux, Michael Tso, Shandy Fox, W. Bradley Jacobs
Publication date: Available online 2 October 2020Source: World NeurosurgeryAuthor(s): Daisuke Sato, Shotaro Ogawa, So Fujimoto, Takeya Suzuki, Masayuki Ueda, Takahiro Ota
Publication date: Available online 2 October 2020Source: World NeurosurgeryAuthor(s): Mihir Gupta, Varun Sagi, Anudeep Yekula, Eugene Golts, John S. Lane, J. Scott Pannell
Publication date: Available online 2 October 2020Source: World NeurosurgeryAuthor(s): Jose Luis Porras, Rajiv Mallipudi, Daniel Michael Sciubba
Publication date: Available online 2 October 2020Source: World NeurosurgeryAuthor(s): Tarek Y. El Ahmadieh, Nicole M. Bedros, Sonja E. Stutzman, Daniel Nyancho, Aardhra M. Venkatachalam, Matthew MacAllister, Vin Shen Ban, Nader S. Dahdaleh, Venkatesh Aiyagari, Stephen Figueroa, Jon A. White, Hunt Batjer, Carlos A. Bagley, H. DaiWai M. Olson, Salah G. Aoun
Publication date: Available online 1 October 2020Source: Journal of Neuroscience MethodsAuthor(s): Cristian Rodriguez Rivero, Jochen Ditterich
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