Publication date: January–February 2021Source: American Journal of Otolaryngology, Volume 42, Issue 1Author(s): Samuel F. Weinreb, Krzysztof Piersiala, Alexander T. Hillel, Lee M. Akst, Simon R. Best
Fri Oct 09, 2020 16:07
Publication date: Available online 8 October 2020Source: Auris Nasus LarynxAuthor(s): Ippei Kishimoto, Hiroe Ohnishi, Kohei Yamahara, Takayuki Nakagawa, Masaru Yamashita, Koichi Omori, Norio Yamamoto
Fri Oct 09, 2020 20:34
Nasal septal schwannoma is a rare tumor. It causes complaints such as nasal congestion, nosebleeds, and headaches. There are many diseases such as nasal polyps, antrochoanal polyp, chronic rhinosinusitis, concha bullosa, inverted papilloma, and retention cyst with schwannoma diagnosis. The diagnosis is made histopathologically, and the treatment is surgery. In this case report, we presented a male patient with septal schwannoma who had nasal obstruction for a year and reviewed the last 20 years of...
Sat Oct 10, 2020 10:20
Introduction. Although rare, cholesteatoma can develop as a late complication of cochlear implantation. The electrode array may then be exposed in the external auditory canal surrounded by cholesteatoma debris. Case Report. The cochlear implant of a child was inadvertently explanted by a clinician during a routine aural toilet procedure. The child had previously reported recurrent ear infections, pain, and unexplained implant function degradation. Reimplantation was carried out 2 days later with...
Fri Oct 09, 2020 16:20
Condition: Esophageal CancerIntervention: Behavioral: PrehabilitationSponsor: McGill University Health Centre/Research Institute of the McGill University Health CentreRecruiting
Fri Oct 09, 2020 16:06
Study to Evaluate the Efficacy, Safety and Pharmacokinetics of CT041 Autologous CAR T-cell Injection
Conditions: Gastric Adenocarcinoma; Pancreatic Cancer; Gastroesophageal Junction AdenocarcinomaIntervention: Drug: CT041 autologous CAR T-cell injectionSponsors: Carsgen Therapeutics, Ltd.; Beijing Cancer Hospital; Fudan UniversityNot yet recruiting
Fri Oct 09, 2020 16:06
Abstract Purpose To investigate the efficacy and safety of bencycloquidium bromide nasal spray (BCQB) in patients with persistent allergic rhinitis (PAR). Methods We enrolled 720 patients from 15 hospitals across China and randomly assigned them into BCQB group or placebo group (90 μg per nostril qid) to receive a 4-week treatment. Visual analog...
Sat Oct 10, 2020 06:59
Sat Oct 10, 2020 06:59
Abstract Purpose MALAT1 is recognized as an oncogenic lncRNA in various malignancies. Here, the authors aim to explore the association of MALAT1 expression and prognostic implication in tongue squamous cell carcinoma (SCC). Methods The tongue tissues of 128 tongue SCC cases satisfying strict follow-up criteria and 28 normal cases were subjected...
Sat Oct 10, 2020 06:59
Abstract Purpose A fluorescence-based technique for the detection of parathyroid glands (PGs) intraoperatively was previously reported. The technique was based on the phenomenon in which PGs emit autofluorescence when exposed to near-infrared light and we undertook an evaluation to consider the pathological accuracy of the method. Methods The...
Sat Oct 10, 2020 06:59
Abstract Purpose Enhanced management of the pre-term patient has resulted in improved survival rates in increasingly premature patients. Although prematurity predisposes to congenital airway pathology, there is also increased risk of endotracheal intubation, and therefore acquired subglottic pathology. We sought to evaluate airway pathology in children outside the neonatal period with a history of prematurity to explore the relationship...
Sat Oct 10, 2020 06:59
Abstract Background To repair a blow-out fracture, the endonasal approach is indicated when the center of the fracture occurs in the orbital floor medial to the infraorbital nerve, or when the orbital tissue is herniated inwards; additionally, the combined endonasal and transmaxillary approach is indicated for fractures of the anterior and lateral parts of the orbital floor. ...
Sat Oct 10, 2020 06:59
Abstract Objective This study aimed to compare patients who had chronic otitis media with and without cholesteatoma in terms of the quality of life related to health. Methods The Turkish version of the Chronic Otitis Media Questionnaire-12 (COMQ-12) was completed by totally 100 healthy subjects and 100 patients who had chronic otitis media (COM)....
Sat Oct 10, 2020 06:59
Abstract Objectives/hypothesis This study was designed to evaluate the graft healing effect of topical application of platelet-rich plasma (PRP) for laryngotracheal reconstruction (LTR) in a rabbit model. Study design It is a prospective randomized control animal study. Materials...
Sat Oct 10, 2020 06:59
Abstract Objectives In the past literature agreed on treating oral carcinomas, using an “en-bloc” resection (EBR) but recently minimally invasive transoral surgery has spread as the preferable treatment for selected cases. This latter technique, which is performed with a discontinuous resection (DR), allows for a satisfactory postoperative quality of life (QoL) maintaining good survival rates. ...
Sat Oct 10, 2020 06:59
Abstract Purpose To review the current management of arytenoid subluxation/dislocation (AS/AD) focusing on diagnostic, therapeutic, and prognostic controversies. Methods The international literature of the last 20 years has been considered. After the application of inclusion criteria, 20 studies were selected (471 AS/AD cases in total). ...
Sat Oct 10, 2020 06:59
Abstract Purpose To introduce modified submental platysmal adipomyofascial flap as a new and viable hairless locoregional option for reconstruction of small- to mid-sized defects after ablative surgery in oral/oropharyngeal cancer patients keeping in mind the present pandemic situation. Methods An observational retrospective study was conducted using modified...
Fri Oct 09, 2020 03:00
Abstract Purpose To examine the concordance between cervical vestibular-evoked myogenic potential (cVEMP) tuning property test results and MRI findings of endolymphatic hydrops (EH). Methods Fourteen subjects (age 24–76 years) that had been diagnosed with unilateral definite Meniere’s disease (MD) (N = 8) or unilateral probable MD (N = 6) were enrolled. All...
Fri Oct 09, 2020 03:00
Abstract Purpose The decline of sensory systems during aging has been widely investigated and several papers have correlated the visual, hearing and vestibular systems and the consequences of their functional degeneration. Hearing loss and presbyvestibulopathy have been found to be positively correlated as is with the risk-to-fall. Material and methods ...
Fri Oct 09, 2020 03:00
Abstract The molecular nature of the hair cycle clock (HCC), i.e. the intrinsic oscillator system that drives hair follicle (HF) cycling, remains incompletely understood; therefore, all relevant key players need to be identified. Here, we present evidence that implicates myelin protein zero‐ like 3 (MPZL3), a multifunctional nuclear‐encoded mitochondrial protein known to be involved in epidermal differentiation, in HCC regulation. By analysing global Mpzl3 knockout (‐/‐) mice, we show that in the...
Sun Oct 11, 2020 22:20
Abstract The pathogenesis of cutaneous T‐cell lymphomas is not clear. In recent years the genetic changes in CTCL were explored. The detected mutations showed a great deal of heterogeneity between individual patients. The studies documented various copy number variations (CNV) and single nucleotide variations (SNV) in multiple genes involved in multiple signaling pathways. Recurrently mutated signaling pathways include JAK‐STAT, MAPK, T cell receptor, TNF receptor and NFκB signaling. In the period...
Thu Oct 08, 2020 20:54
Abstract The anatomy of the hair follicle and the dynamics of its barrier provide a special space for interactions between macromolecules and the underlying tissue. Translocation across the hair follicle epithelium and immune recognition have been confirmed for proteins, nucleic acids, engineered particles, virus particles and others. Tissue responses can be modulated by pro‐inflammatory stimuli as demonstrated in penetration and transcutaneous immunization studies. Even under physiological conditions,...
Thu Oct 08, 2020 19:15
Abstract Background The rehabilitation process following cochlear implant (CI) surgery is carried out in a multimodal therapy according to German national guidelines and includes technical and medical aftercare. In times of the corona pandemic surgery and rehabilitation appointments were cancelled or delayed leading to a more difficult access to auditory rehabilitation. Newly implemented hygiene modalities due to the SARS-CoV‑2 pandemic...
Fri Oct 09, 2020 03:00
The evaluation of tinnitus and auditory brainstem response in benign paroxysmal positional vertigo accompanied by tinnitus. Eur Arch Otorhinolaryngol. 2020 Oct 10;: Authors: Kocabaş E, Kutluhan A, Müjdeci B Abstract PURPOSE: The aim of this study is to investigate auditory brainstem response (ABR) in patients with benign paroxysmal positional vertigo (BPPV) accompanied by tinnitus and to suggest possible interpretative hypotheses. ...
Sun Oct 11, 2020 13:49
Modified submental platysmal adipomyofascial flap: is it a reliable alternate reconstructive option for small- to mid-sized defects especially in male patients with oral/oropharyngeal cancer? Eur Arch Otorhinolaryngol. 2020 Oct 09;: Authors: Singh A, Chopra A, Chaudhary S, Venkatasubramaniyan M, Joshi K, Agarwal M Abstract PURPOSE: To introduce modified submental platysmal adipomyofascial flap as a new and viable hairless locoregional option...
Sun Oct 11, 2020 13:49
Association of cervical vestibular-evoked myogenic potential tuning property test results with MRI findings of endolymphatic hydrops in Meniere's disease. Eur Arch Otorhinolaryngol. 2020 Oct 09;: Authors: Murofushi T, Tsubota M, Kanai Y, Endo H, Ushio M Abstract PURPOSE: To examine the concordance between cervical vestibular-evoked myogenic potential (cVEMP) tuning property test results and MRI findings of endolymphatic hydrops (EH). ...
Sun Oct 11, 2020 13:49
Can hearing amplification improve presbyvestibulopathy and/or the risk-to-fall ? Eur Arch Otorhinolaryngol. 2020 Oct 09;: Authors: Ernst A, Basta D, Mittmann P, Seidl RO Abstract PURPOSE: The decline of sensory systems during aging has been widely investigated and several papers have correlated the visual, hearing and vestibular systems and the consequences of their functional degeneration. Hearing loss and presbyvestibulopathy have been found...
Sat Oct 10, 2020 14:08
To identify an age at which initiation of whole nut into the pediatric diet could be considered safe, by evaluating the age distribution of children undergoing bronchoscopy with removal of nut or seed material...
Fri Oct 09, 2020 03:00
When endolaryngeal approaches are inadequate and when there is significant injury to the larynx, transcervical approaches are necessary. This is most often necessary for Schaefer-Fuhrman Class II -IV. Assessment and treatment always begin with evaluation and management of the airway followed by operative endoscopy to determine the extent of injury and guide surgical repair. Treatment includes open reduction and fixation of cartilaginous fractures but when there is significant endolaryngeal injury,...
Fri Oct 09, 2020 03:00
Airway burn injury continues to be a significant cause of morbidity and mortality in the burn patient population. It is essential to identify patients with potential airway obstruction and to avoid potential complications of airway manipulation in those with less severe injury. In this review, the initial evaluation and management of airway burn injuries will be discussed including indications for observation versus intubation versus tracheotomy. Additionally, the long term sequelae of upper airway...
Fri Oct 09, 2020 03:00
There are enough firearms in the United States that every man, woman and child can have one and still 67 million would be left over. Penetrating trauma from firearms has increased recently with easier availability of military grade weapons to civilians and an increased incidence of terrorism. Understanding of wound ballistics has a definite role in the betterment of neck trauma management. This article discusses the mechanisms of penetrating neck trauma with special emphasis on penetrating projectile...
Fri Oct 09, 2020 03:00
Burns of the face and neck are devastating injuries with significant psychological and functional morbidity. A detailed understanding of the severity of head and neck burns is key to effective acute management of these injuries and prevention of long-term complications. This article focuses on acute management of burns of the face and skin both in the inpatient setting and managing the sequelae of facial burns including hypertrophic scarring, contractures, and functional issues such as microstomia...
Fri Oct 09, 2020 03:00
: Our objective was to use a series of cases from the wars in Iraq and Afghanistan to highlight challenges in treating in head and neck trauma in a resource constrained environment either in a deployed military or humanitarian settings.
Fri Oct 09, 2020 03:00
Pharyngoesophageal injury has high morbidity and mortality despite advances in diagnostics and surgical therapy. It is essential to rapidly identify patients injury to avoid severe sequelae. In this review, the common etiologies of penetrating esophageal injury will be reviewed as well as the initial evaluation and diagnostic techniques. Management of pharyngoesophageal injuries will be discussed including indications for observation, endoscopic management or open surgical repair.
Fri Oct 09, 2020 03:00
Benjamin Franklin said “by failing to prepare you are preparing to fail“. There is no substitute for knowledge about trauma, however, we may not always have all the tools we need to succeed, especially in trauma situations because we do not have time to get ready. Trauma is not a scheduled event and comprehensive knowledge of trauma is not readily available, especially in civilian centers. During my training in a major city hospital and a Veterans Administration hospital, we frequently were without...
Fri Oct 09, 2020 03:00
This article addresses specific issues related to otologic trauma. It includes a summary of key general considerations, and a review of the main symptoms and pathology that may arise following otologic trauma. It focuses on tympanic membrane perforation with a discussion of management and operative techniques of the varied presentations of this disorder.
Fri Oct 09, 2020 03:00
Craniofacial trauma accounts for a large number of medical encounters in the United States and is associated with significant morbidity and mortality. The role of imaging, particularly computed tomography (CT) and CT angiography (CTA) can significantly enhance the evaluation of patients with craniofacial trauma, assisting with appropriate management and surgical planning. Radiologic studies additionally provide information about soft tissue and vascular trauma which cannot always be excluded by physical...
Thu Oct 08, 2020 03:00
Laryngotracheal and pharyngoesophageal injuries are a relatively rare component of head and neck trauma; however, if not managed correctly, the consequences of these injuries can be life threatening. The early management of these injuries involves bedside endoscopic evaluation, often followed by formal endoscopy in the operating room. While many of these patients may require open surgical procedures, some of these injuries, and especially the long-term complications they cause, can be managed endoscopically.
Thu Oct 08, 2020 03:00
Publication date: Available online 10 October 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): P. Reynard, M. Montero, A. Alhamwi, A. Neagu, E. Veuillet, H. Thai-Van
Sat Oct 10, 2020 16:24
Publication date: Available online 9 October 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): S. Bonnafous, R. Hermann, S. Zaouche, S. Tringali, M. Fieux
Sat Oct 10, 2020 16:24
Publication date: Available online 8 October 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): H.J. Jung, J.Y. Lee, Y.-S. Choi, H.G. Choi, J.H. Wee
Fri Oct 09, 2020 16:19
Publication date: December 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 139Author(s): Varun Bora, Anthony Olive, Eric Chiou, Priya Raj, Deepak Mehta
Sun Oct 11, 2020 22:43
Publication date: December 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 139Author(s): Jonathan A. Harounian, Garrett Ni, Michele M. Carr
Sun Oct 11, 2020 22:43
Publication date: December 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 139Author(s): Johannes Voelker, Christine Voelker, Jonas Engert, Philipp Schendzielorz, Rudolf Hagen, Kristen Rak
Sun Oct 11, 2020 22:43
Publication date: December 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 139Author(s): Prahasit Thirkateh, Sarah M. Walner, David L. Walner
Sat Oct 10, 2020 14:36
Publication date: December 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 139Author(s): Christina Darwish, Timothy Shim, Andrew D. Sparks, Yeshwant Chillakuru, David Strum, Daniel A. Benito, Ashkan Monfared
Sat Oct 10, 2020 14:36
Publication date: December 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 139Author(s): Carlos Henrique Santos Ferreira, Ricardo Reis Dinardi, Cássio da Cunha Ibiapina, Cláudia Ribeiro de Andrade
Fri Oct 09, 2020 14:13
Publication date: December 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 139Author(s): Weining Yang, Daniel Milad, Nikolaus E. Wolter, Evan J. Propst, Yvonne Chan
Fri Oct 09, 2020 14:13
Peri‐procedural Anticoagulation in Patients with Head and Neck Versus Extremity Venous Malformations
Objective (1) Review a multidisciplinary vascular anomalies center's practice regarding periprocedural anticoagulation for venous malformations (VM) and the associated risk of thromboembolic and disseminated intravascular coagulation (DIC) events. (2) Compare the risk of thromboembolic events and DIC post‐procedure between head and neck (H&N) and extremity VM patients. Methods An Institutional Review Board (IRB)‐approved, retrospective chart review was performed on 120 VM patients. A thromboembolic...
Sat Oct 10, 2020 14:49
Objective To evaluate the effectiveness of neuromodulating agents for the management of atypical facial pain and primary facial neuralgias. Methods We searched MEDLINE, Embase, CINAHL, and ClinicalTrials.gov databases for original research articles that examine the effectiveness and adverse reactions of pharmacologic therapy for the treatment of trigeminal neuralgia and atypical facial pain. Studies that included surgical interventions for atypical facial pain or facial pain secondary to other...
Sat Oct 10, 2020 14:47
Objective A paucity of data exists regarding surgical outcomes for patients undergoing total laryngectomy for a dysfunctional larynx. Herein, we present the largest study evaluating the method of closure on postoperative fistula rate and swallowing ability. Method We performed a retrospective review of patients undergoing total laryngectomy for a dysfunctional larynx after primary radiation or chemoradiation therapy for laryngeal carcinoma from 1998 to 2020. Demographic information, operative...
Sat Oct 10, 2020 14:41
Objectives/Hypothesis Create a competency‐based assessment tool for pediatric esophagoscopy with foreign body removal. Study Design Blinded modified Delphi consensus process. Setting Tertiary care center. Methods A list of 25 potential items was sent via the Research Electronic Data Capture database to 66 expert surgeons who perform pediatric esophagoscopy. In the first round, items were rated as “keep” or “remove” and comments were incorporated. In the second round, experts rated...
Fri Oct 09, 2020 14:59
Introduction: Iodine is an essential micronutrient and its deficiency can severely impact children’s development. In 2012, the Thyroid Study Group of the Portuguese Society of Endocrinology, Diabetes and Metabolism discovered that the median urinary iodine concentration (mUIC) level in schoolchildren of São Miguel was far too low at 70.9 μg/L. In response, the government implemented a salt iodization program to help normalize levels. This investigation evaluated the efficacy of such an approach....
Fri Oct 09, 2020 13:01
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