Histopathological features of Chilblain-like lesions developing in the setting of the COVID-19 pandemic. Arch Pathol Lab Med. 2020 Oct 09;: Authors: Sohier P, Matar S, Meritet JF, Laurent-Roussel S, Dupin N, Aractingi S Abstract CONTEXT: During the coronavirus disease 2019 pandemic, several studies have described a distinctive cutaneous manifestation with a clinical picture resembling chilblains or chilblain lupus in young patients. ...
Sat Oct 10, 2020 14:17
Neuraxial and regional anesthesia in surgical patients with osteogenesis imperfecta: a narrative review of literature. Reg Anesth Pain Med. 2020 Oct 09;: Authors: Beethe AR, Bohannon NA, Ogun OA, Wallace MJ, Esposito PW, Lockhart TJ, Hamlin RJ, Williams JR, Goeller JK Abstract BACKGROUND AND OBJECTIVES: Regional and neuraxial anesthesia techniques have become instrumental in the perioperative period yet have not been well described in...
Sun Oct 11, 2020 15:36
Chronic pain and psychedelics: proceeding with caution. Reg Anesth Pain Med. 2020 Oct 08;: Authors: Mukhdomi T, Mukhdomi J PMID: 33033160 [PubMed - as supplied by publisher]
Sat Oct 10, 2020 15:26
Response to Mukhdomi and Mukhdomi's letter to the editor. Reg Anesth Pain Med. 2020 Oct 08;: Authors: Castellanos JP, Woolley C, Bruno KA, Zeidan F, Halberstadt A, Furnish T PMID: 33033159 [PubMed - as supplied by publisher]
Sat Oct 10, 2020 15:26
The world needs our science: broadening the research pipeline in anesthesiology. Reg Anesth Pain Med. 2020 Oct 07;: Authors: Adams MCB, Memtsoudis SG Abstract Anesthesiologists are innovative and adaptable problem solvers. Despite these talents, our field is still working to consistently develop and support the translation of innovation and creativity into productive scientists. This article is focused on opening the discussion on identifying...
Fri Oct 09, 2020 15:39
Alar Base Augmentation Using Vomerine Bone Graft in Patients With Cleft Lip Nasal Deformity. Ann Plast Surg. 2020 Nov;85(5):511-515 Authors: Elfeki B, Elhussiny Khater AM, Bahaa El-Din AM, Shouman OO, Baek RM, Kim BK Abstract BACKGROUND: Although many trials have been made to augment the unilateral alar base depression, the ultimate aesthetic satisfaction has proven difficult to achieve. In our study, we present a novel submucosal dissection...
Sat Oct 10, 2020 15:08
Opposite-Running Double Abdominal Flap on Single Pivot Point (Udaipur Flap) for Circumferential Coverage of Wrist and Hand. Ann Plast Surg. 2020 Nov;85(5):495-501 Authors: Petkar K Abstract Complete or near circumferential defects over wrist and hand are difficult situations. They need flaps so long that available adjacent, distant or free flaps often seem inadequate. Hence, this innovative solution was designed. Twin axial flaps were elevated...
Sat Oct 10, 2020 15:08
[Let us also take into account the TRALI-associated cell transplant risks]. Bull Cancer. 2020 Oct 06;: Authors: Lafarge X PMID: 33036743 [PubMed - as supplied by publisher]
Sun Oct 11, 2020 15:03
[Nomadism of patients treated by radiotherapy in Île-de-France: Does our health system have as much money to waste?] Bull Cancer. 2020 Oct 06;: Authors: Paix A, Popotte H, Lévy C, Perez A, Bouillet T, Zelek L, Duchemann B Abstract PURPOSE: Human, material, and financial resources being limited, the organization of the care system must allow an efficient allocation of resources. The management of cancers leads to specific and repetitive care...
Sun Oct 11, 2020 15:03
[Non endometroid endometrial cancer guidelines evaluation: A multicentric retrospective study]. Bull Cancer. 2020 Oct 06;: Authors: Scattarelli A, Poteau A, Aziz M, Lae M, Courville P, Arnaud M, Marpeau L, Resch B Abstract INTRODUCTION: Non endometrioid endometrial cancer are infrequent and have poor prognosis. The aim of the study was to evaluate non endometrioid endometrial cancer managment by evaluating endometrial cancer guidelines application....
Sun Oct 11, 2020 15:03
[Attachment and caregivers' life course facing cancer]. Bull Cancer. 2020 Oct 06;: Authors: Bonnet M, Vadam F, Belot RA, Quibel C, Pozet A, Nerich V Abstract INTRODUCTION: Since the last cancer plan 2014-2019, the assessment of the impact of the disease on caregivers became essential. The quality of caregiving represents an important part of the patient's quality of life. The main objective was to describe the evolution of caregiver's attachment...
Sun Oct 11, 2020 15:03
[Musculoskeletal tumour surgery for adolescent and young-adult population: Collaboration between adult and pediatric surgeons is necessary]. Bull Cancer. 2020 Oct 06;: Authors: Gouin F, Laurence V, Hamel A, Mascard E Abstract Orthopaedic surgery I has a key role on the medical pathway of adolescent and young-adult (AYA) patients with musculo-skeletal tumor from diagnosis, tumor resection, musculo-skeletal immediate or delayed reconstruction,...
Sun Oct 11, 2020 15:03
Literature meta-analysis about the efficacy of re-challenge with PD-1 and PD-L1 inhibitors in cancer patients. Bull Cancer. 2020 Oct 05;: Authors: Gobbini E, Charles J, Toffart AC, Leccia MT, Moro-Sibilot D, Levra MG Abstract INTRODUCTION: Immune checkpoint inhibitor (ICPis) re-challenge could be an attractive therapeutic option considering its good safety profile. However, little data is available regarding anti-PD-1/anti-PD-L1 retreatment....
Sat Oct 10, 2020 14:57
Practice Variation in Regional Anesthesia Utilization by Current and Former U.S. Military Anesthesiology Residents. Mil Med. 2020 Oct 10;: Authors: Jaffe E, Patzkowski MS, Hodgson JA, Foerschler DL, Gonzalez SC, Giordano NA, Scott-Richardson MP, Highland KB Abstract INTRODUCTION: Per Joint Trauma System guidelines, military anesthesiologists are expected to be ready to lead an Acute Pain Service with regional anesthesia in combat casualty care....
Sun Oct 11, 2020 13:40
Turkish Armed Forces Combat Medic Course: Predictors of Trainee Success. Mil Med. 2020 Oct 10;: Authors: Yıldırım M, Çetin M PMID: 33038248 [PubMed - as supplied by publisher]
Sun Oct 11, 2020 13:40
Case Series of Arterial Gas Embolism Incidents in U.S. Navy Pressurized Submarine Escape Training From 2018 to 2019. Mil Med. 2020 Oct 10;: Authors: Edgar M, Franco MA, Dainer HM Abstract The goal of Pressurized Submarine Escape Training (PSET) is to prepare future submariners for the physical and mental challenges of escaping a disabled submarine and promote proper handling of the Beaufort Ltd Mk 11 Submarine Escape and Immersion Equipment...
Sun Oct 11, 2020 13:40
Melon with a Twist: A Case of Nicotine Overdose After Ingestion and Aspiration of Vape Liquid. Mil Med. 2020 Oct 10;: Authors: Jude J, Hiller H, Miller J Abstract We present the case of an active duty 21-year-old male with severe hypoxic respiratory failure after accidentally ingesting, and subsequently aspirating, vaping liquid while intoxicated. Because of the increasing prevalence of vaping devices, this case highlights a unique risk of...
Sun Oct 11, 2020 13:40
Authors' Reply to the Response to Our Article ("A Comparison of Improvised and Commercially Available Point-of-Wounding Tourniquets in Simulated Traumatic Amputation with Catastrophic Haemorrhage"). Mil Med. 2020 Oct 10;: Authors: Hay-David AGC, Herron JBT, Thurgood A, Whittle C, Mahmood A, Bodger O, Hodgetts TJ, Pallister I PMID: 33038237 [PubMed - as supplied by publisher]
Sun Oct 11, 2020 13:40
Subannular ventilation tubes in the pediatric population: Clinical outcomes of over 1000 insertions.
Related Articles Subannular ventilation tubes in the pediatric population: Clinical outcomes of over 1000 insertions. Int J Pediatr Otorhinolaryngol. 2020 Apr;131:109859 Authors: Yang N, Beaudoin PL, Nguyen M, Maillé H, Maniakas A, Saliba I Abstract OBJECTIVES: Long-term transtympanic tube insertions for chronic middle ear disease are associated with high rates of complications. The objective of this study was to examine the clinical outcomes...
Sat Oct 10, 2020 17:44
Is it possible to estimate volume of bone defects formed on dry sheep mandibles more practically by secondarily reconstructing section thickness of cone beam computed tomography images? Dentomaxillofac Radiol. 2020 Oct 09;:20200400 Authors: Koç A, Kaya S Abstract OBJECTIVES: The purpose of this study was to evaluate the effect of section thickness on volume estimations of bone defects scanned using cone beam computed tomography (CBCT)....
Sat Oct 10, 2020 18:36
Are long-term influenza vaccines possible and how do we discover them? Expert Opin Drug Discov. 2020 Oct 08;:1-4 Authors: Kim JK, Kang SM, Compans RW, Wang BZ PMID: 33030353 [PubMed - as supplied by publisher]
Fri Oct 09, 2020 15:58
Quality of cochlear implant rehabilitation under COVID-19 conditions. HNO. 2020 Oct 09;: Authors: Aschendorff A, Arndt S, Kröger S, Wesarg T, Ketterer MC, Kirchem P, Pixner S, Hassepaß F, Beck R Abstract BACKGROUND: The rehabilitation process following cochlear implant (CI) surgery is carried out in a multimodal therapy according to German national guidelines and includes technical and medical aftercare. In times of the corona pandemic...
Sat Oct 10, 2020 13:42
Out-of-season increase of puerperal fever with group A Streptococcus infection: a case-control study, Netherlands, July to August 2018. Euro Surveill. 2020 Oct;25(40): Authors: van den Boogaard J, Hahné SJ, Te Wierik MJ, Knol MJ, Balasegaram S, de Gier B Abstract We observed an increase in notifications of puerperal group A Streptococcus (GAS) infections in July and August 2018 throughout the Netherlands without evidence for common sources....
Sat Oct 10, 2020 16:30
Job vacancy at Eurosurveillance. Euro Surveill. 2020 Oct;25(40): Authors: Eurosurveillance editorial team PMID: 33034282 [PubMed - in process]
Sat Oct 10, 2020 16:30
Epidemiological parameters of COVID-19 and its implication for infectivity among patients in China, 1 January to 11 February 2020. Euro Surveill. 2020 Oct;25(40): Authors: Lu QB, Zhang Y, Liu MJ, Zhang HY, Jalali N, Zhang AR, Li JC, Zhao H, Song QQ, Zhao TS, Zhao J, Liu HY, Du J, Teng AY, Zhou ZW, Zhou SX, Che TL, Wang T, Yang T, Guan XG, Peng XF, Wang YN, Zhang YY, Lv SM, Liu BC, Shi WQ, Zhang XA, Duan XG, Liu W, Yang Y, Fang LQ Abstract BackgroundThe...
Sat Oct 10, 2020 16:30
Detection of West Nile virus in a common whitethroat (Curruca communis) and Culex mosquitoes in the Netherlands, 2020. Euro Surveill. 2020 Oct;25(40): Authors: Sikkema RS, Schrama M, van den Berg T, Morren J, Munger E, Krol L, van der Beek JG, Blom R, Chestakova I, van der Linden A, Boter M, van Mastrigt T, Molenkamp R, Koenraadt CJ, van der Brand JM, Oude Munnink BB, Koopmans MP, van der Jeugd H Abstract On 22 August, a common whitethroat...
Sat Oct 10, 2020 16:30
Job vacancies at the European Centre for Disease Prevention and Control (ECDC). Euro Surveill. 2020 Oct;25(40): Authors: Eurosurveillance editorial team PMID: 33034279 [PubMed - in process]
Sat Oct 10, 2020 16:30
Authors' correction for Euro Surveill. 2020;25(39). Euro Surveill. 2020 Oct;25(40): Authors: Eurosurveillance editorial team PMID: 33034278 [PubMed - in process]
Sat Oct 10, 2020 16:30
Pediatric nasal dermoid- a decade's experience from a South Indian tertiary care centre. Int J Pediatr Otorhinolaryngol. 2020 Oct 01;139:110418 Authors: Naina P, Jonathan GE, Prabhakar M, Irodi A, Syed KA, John M, Varghese AM Abstract INTRODUCTION: Nasal dermoid sinus cyst (NDSC) are uncommon congenital lesions in children. OBJECTIVE: To review the clinical and radiological presentation and study the surgical outcomes of this uncommon...
Sat Oct 10, 2020 14:04
Radiological evidence to changes in the olfactory bulb volume depending on body mass index in the childhood. Int J Pediatr Otorhinolaryngol. 2020 Oct 05;139:110415 Authors: Karaoglan M, Colakoglu Er H Abstract OBJECTIVE: Energy balance is preserved through the exchange between body weight and adipose tissue across the multi-faceted complex network that is composed of the sensorial, metabolic, and neuro-endocrine circuits. The olfactory control...
Sat Oct 10, 2020 14:04
Pediatric obstructive sleep apnea revisited: Perioperative considerations for the pediatric Anesthesiologist. Int J Pediatr Otorhinolaryngol. 2020 Oct 03;139:110420 Authors: Chandrakantan A, Mehta D, Adler AC Abstract Pediatric obstructive sleep apnea presents in up to 7% of children and represents a constellation from nasal turbulence to cessation in gas exchange. There are numerous end organ sequelae including neurocognitive morbidity associated...
Sat Oct 10, 2020 14:04
Effect of delivery mode on neonate auditory brainstem responses to air- and bone-conducted stimuli. Int J Pediatr Otorhinolaryngol. 2020 Oct 04;139:110423 Authors: Stuart A Abstract OBJECTIVES: The object of this study was to examine if caesarean section delivered neonates have different middle ear function relative to neonates with vaginal delivery. METHODS: Auditory brainstem responses (ABRs) were examined in caesarean section delivered...
Sat Oct 10, 2020 14:04
Anthropometry: A clue for Otorhinolaryngology surgical indications in children. Int J Pediatr Otorhinolaryngol. 2020 Oct 03;139:110421 Authors: Sousa FA, Castro AD, Machado AS, Pinto AN, Coutinho MB, Sousa CAE Abstract BACKGROUND: There are reports in literature concerning the relation between some maternal and neonatal factors and future risk of disease, including atopy, recurrent infections and obstructive sleep disturbances, three common...
Sat Oct 10, 2020 14:04
Cross-cultural adaptation of the sinus and nasal quality of life survey (SN-5) to Spanish. Int J Pediatr Otorhinolaryngol. 2020 Oct 03;139:110425 Authors: Calvo-Henríquez C, Valencia-Blanco B, Boronat-Catalá B, Maza-Solano J, Díaz-Anadón Á, Kahn S, Moure-Gonzalez JD, Faraldo-García A, Martinez-Capoccioni G Abstract OBJECTIVE: There is a high prevalence for rhinitis with an increasing trend. However, there is a lack of specific quality of life...
Fri Oct 09, 2020 14:32
Effects of familial Mediterranean fever on the middle ear. Int J Pediatr Otorhinolaryngol. 2020 Sep 30;139:110417 Authors: Cetin AC, Acari C, Evin H, Omer Ikiz A, Kirkim G, Unsal E Abstract OBJECTIVE: To evaluate middle and inner ear function and hearing status of children with familial Mediterranean fever (FMF). METHODS: We assigned 56 patients with FMF to the study group and 52 healthy volunteers to the control group. The mean age...
Fri Oct 09, 2020 14:32
Randomized CLINICAL TRIAL comparing side to end VS end to end techniques for colorectal anastomosis.
Randomized CLINICAL TRIAL comparing side to end VS end to end techniques for colorectal anastomosis. Int J Surg. 2020 Oct 07;: Authors: Planellas P, Farrés R, Cornejo L, Rodríguez-Hermosa JI, Pigem A, Timoteo A, Ortega N, Codina-Cazador A Abstract BACKGROUND: Low anterior resection syndrome affects 60% to 90% of patients with anastomoses after colorectal resection. Consensus regarding the best anastomosis is lacking. OBJECTIVE:...
Sun Oct 11, 2020 13:19
An invited commentary on "No alteration of CYP3A4 activity after major hepatectomy in early postoperative period - A prospective before-after study" (Int J Surg 2020; 79;131-135). Int J Surg. 2020 Oct 06;: Authors: Theodoridis C, Lykoudis PM PMID: 33035663 [PubMed - as supplied by publisher]
Sat Oct 10, 2020 13:19
Vestibular Neuritis in Patients among Different Age Groups: Clinical Features and Outcomes. J Am Acad Audiol. 2020 Oct 09;: Authors: Yan T, Zong F, Han X, Wang X, Li Q, Qiao R, Zhang H Abstract BACKGROUND: Patients with vestibular neuritis (VN) displayed differential prognosis despite of the same treatment. Thus, identifying unique characteristics in different populations and creating individually customized treatments are necessary....
Sun Oct 11, 2020 03:58
The Effect of Hearing Loss on Localization of Amplitude-Panned and Physical Sources. J Am Acad Audiol. 2020 Oct 08;: Authors: Ellis GM, Souza PE Abstract BACKGROUND: Clinics are increasingly turning toward using virtual environments to demonstrate and validate hearing aid fittings in "realistic" listening situations before the patient leaves the clinic. One of the most cost-effective and straightforward ways to create such an environment...
Sat Oct 10, 2020 03:59
Hybrid optogenetic and electrical stimulation for greater spatial resolution and temporal fidelity of cochlear activation. J Neural Eng. 2020 Oct 09;: Authors: Thompson A, Wise AK, Hart W, Needham K, Fallon JB, Gunewardene N, Stoddart PR, Richardson RT Abstract OBJECTIVE: Compared to electrical stimulation, optogenetic stimulation has the potential to improve the spatial precision of neural activation in neuroprostheses, but it requires intense...
Sat Oct 10, 2020 14:29
Supervised machine learning tools: a tutorial for clinicians. J Neural Eng. 2020 Oct 09;: Authors: Lo Vercio L, Amador K, Bannister JJ, Crites S, Gutierrez A, MacDonald ME, Moore J, Mouches P, Rajasheka D, Schimert S, Subbanna N, Tuladhar A, Wang N, Wilms M, Winder A, Forkert ND Abstract In an increasingly data-driven world, artificial intelligence is expected to be a key tool for converting big data into tangible benefits and the healthcare...
Sat Oct 10, 2020 14:29
Network structure of cascading neural systems predicts stimulus propagation and recovery. J Neural Eng. 2020 Oct 09;: Authors: Ju H, Kim JZ, Beggs JM, Bassett DS Abstract Many neural systems display spontaneous, spatiotemporal patterns of neural activity that are crucial for information processing. While these cascading patterns presumably arise from the underlying network of synaptic connections between neurons, the precise contribution of...
Sat Oct 10, 2020 14:29
Vascularised composite allotransplantation in solid organ transplant recipients: A systematic review. J Plast Reconstr Aesthet Surg. 2020 Aug 26;: Authors: Honeyman C, Stark HL, Fries CA, Gorantla VS, Davis MR, Giele H Abstract INTRODUCTION: A solid organ transplant (SOT) recipient, already taking immunosuppression, may represent the ideal candidate for vascularised composite allograft transplantation (VCA). However, concerns have been raised...
Sun Oct 11, 2020 16:14
Anatomical location of the primary tumour and its relationship to regional lymph node metastasis in cutaneous head and neck melanoma: Is selective neck dissection appropriate? J Plast Reconstr Aesthet Surg. 2020 Sep 28;: Authors: Opel S, Jamshidi S, Butler D, Matteucci P, Stanley PRW, Dunne J, Saleh D PMID: 33036925 [PubMed - as supplied by publisher]
Sun Oct 11, 2020 16:14
Contemporary evidence of art's relevance to the modern plastic surgeon. J Plast Reconstr Aesthet Surg. 2020 Sep 28;: Authors: Kearns C PMID: 33032961 [PubMed - as supplied by publisher]
Sat Oct 10, 2020 16:09
Response to: "A survey of current burns knowledge in UK undergraduate medical students". J Plast Reconstr Aesthet Surg. 2020 Sep 28;: Authors: Iqbal S, Raja U, Alam A PMID: 33028490 [PubMed - as supplied by publisher]
Fri Oct 09, 2020 16:21
Erratum: Using a Virtual Reality Walking Simulator to Investigate Pedestrian Behavior. J Vis Exp. 2020 Oct 08;(164): Authors: Abstract An erratum was issued for: Using a Virtual Reality Walking Simulator to Investigate Pedestrian Behavior. An affiliation was updated. The first affiliation was updated from: Department of Sports Science, Kunsan National University to: Department of Sport and Exercise Sciences, Kunsan National University....
Fri Oct 09, 2020 15:04
Reconstructive Options During Nonfunctional Laryngectomy. Laryngoscope. 2020 Oct 10;: Authors: Escalante D, Vincent AG, Wang W, Shokri T, Ducic Y Abstract OBJECTIVE: A paucity of data exists regarding surgical outcomes for patients undergoing total laryngectomy for a dysfunctional larynx. Herein, we present the largest study evaluating the method of closure on postoperative fistula rate and swallowing ability. METHOD: We performed...
Sun Oct 11, 2020 15:31
Machine learning-based FDG PET-CT radiomics for outcome prediction in larynx and hypopharynx squamous cell carcinoma. Clin Radiol. 2020 Oct 06;: Authors: Zhong J, Frood R, Brown P, Nelstrop H, Prestwich R, McDermott G, Currie S, Vaidyanathan S, Scarsbrook AF Abstract AIM: To determine whether machine learning-based radiomic feature analysis of baseline integrated 2-[18F]-fluoro-2-deoxy-d-glucose (FDG) positron-emission tomography (PET) computed...
Sun Oct 11, 2020 15:31
Nonepithelial Tumors of the Larynx: Single-Institution 13-Year Review with Radiologic-Pathologic Correlation. Radiographics. 2020 Oct 09;:190210 Authors: Ong AC, Huh EH, Moreland AJ, Rooper LM, Aygun N, Akst LM, Best SR, Khan MA Abstract Nonepithelial tumors of the larynx are rare and represent a minority of all laryngeal neoplasms. Imaging has an important role in the diagnosis, treatment planning, and surveillance of these entities. However,...
Sat Oct 10, 2020 15:35
Preliminary Simulation Study of Carotid Artery and Pharyngeal Constrictor Muscle Sparing-Radiotherapy in Glottic Carcinoma. Technol Cancer Res Treat. 2020 Jan-Dec;19:1533033820956989 Authors: Ozdemir Y, Acibuci I, Selek U, Topkan E Abstract BACKGROUND: This preliminary simulation study aimed to compare the dosimetric outcomes of carotid arteries (CAs) and pharyngeal constrictor muscle (PCM) in patients with T1N0M0 glottic carcinoma undergoing...
Sat Oct 10, 2020 15:35
Innervation of Human Soft Palate Muscles. Anat Rec (Hoboken). 2020 Oct 09;: Authors: Mu L, Chen J, Li J, Fowkes M, Benson B, Nyirend T, Sobotka S, Christopherson M, Sanders I Abstract Our objective was to determine the branching and distribution of the motor nerves supplying the human soft palate muscles. Six adult specimens of the soft palate in continuity with the pharynx, larynx and tongue were processed with Sihler's stain, a technique...
Sat Oct 10, 2020 15:35
What do Sopranos and Singing Teachers Think About Upper High Range Notes? J Voice. 2020 Oct 05;: Authors: Fernandes DE, Andrada E Silva MA Abstract BACKGROUND: Despite being widely used by professional sopranos, the emission of upper high range notes is still a subject of considerable controversy both to those who use them and those who study them. OBJECTIVE: To compare the opinion of sopranos and singing teachers on the emission of...
Sat Oct 10, 2020 15:35
Voice-Related Quality of Life, Anxiety, and Depression in Female Teachers: Finger Kazoo Intensive Short-Term Vocal Therapy. J Voice. 2020 Oct 05;: Authors: Christmann MK, Scapini F, Lima JPM, Gonçalves BFDT, Bastilha GR, Cielo CA Abstract BACKGROUND: Among professional voice users, teachers are subject to higher risks of developing occupational dysphonia due to their abusive use of the voice, usually under unfavorable conditions. OBJECTIVES:...
Sat Oct 10, 2020 15:35
Related Articles Physiological Compensation for Advanced Bolus Location at Swallow Onset: A Retrospective Analysis in Healthy Seniors. J Speech Lang Hear Res. 2019 12 18;62(12):4351-4355 Authors: Herzberg EG, Brates D, Molfenter SM Abstract Purpose Previous work has established that advanced bolus location at swallow onset (BLSO) alone is not correlated with an increased swallowing safety risk in healthy seniors. The primary goal of this retrospective...
Sat Oct 10, 2020 15:35
Related Articles Ovine Vocal Fold Tissue Fatigue Response to Accumulated, Large-Amplitude Vibration Exposure at Phonatory Frequencies. J Speech Lang Hear Res. 2019 12 18;62(12):4291-4299 Authors: Chan RW Abstract Purpose The contribution of tissue mechanical response to vocal fatigue is poorly understood. This study investigated the fatigue response of vocal fold tissues to large-amplitude vibration exposure at phonatory frequencies, using...
Sat Oct 10, 2020 15:35
Related Articles Multicenter prospective study on the use and outcome of rehabilitation after total laryngectomy in Germany. Head Neck. 2019 04;41(4):1070-1079 Authors: Singer S, Vogel HJ, Guntinas-Lichius O, Erdmann-Reusch B, Fuchs M, Taylor K, Meyer A, Keszte J Abstract BACKGROUND: The purpose of this study was to assess the use and outcome of rehabilitation after total laryngectomy in Germany. METHODS: We enrolled patients who were...
Sat Oct 10, 2020 15:35
Tracheal Agenesis: Vertical Division of the Native Esophagus - A Novel Surgical Approach and Review of the Literature. Ann Otol Rhinol Laryngol. 2020 Oct 08;:3489420962124 Authors: Straughan AJ, Mulcahy CF, Sandler AD, Bauman NM, Steinhorn D, Gitman L Abstract INTRODUCTION: Tracheal agenesis (TA) is rare and usually fatal. Few survivors with concomitant tracheoesophageal fistulae (TEF) who underwent ligation of the distal esophagus with creation...
Fri Oct 09, 2020 15:37
Related Articles Goblet cells promote tolerance induction in the conjunctiva. Mucosal Immunol. 2020 09;13(5):717-718 Authors: Pflugfelder SC, de Paiva CS PMID: 32616838 [PubMed - indexed for MEDLINE]
Fri Oct 09, 2020 15:37
Bilateral "Rescue Strip" Technique for Endoscopic Endonasal Approaches to the Clivus. Oper Neurosurg (Hagerstown). 2020 Oct 09;: Authors: Kim M, Otten M, Overdevest JB, Gudis DA Abstract BACKGROUND: The vascularized nasoseptal flap (NSF) is a pillar of contemporary endoscopic skull base reconstruction. The pedicle for the NSF is supplied by the posterior septal branch of the sphenopalatine artery, which courses along the arch of the choana...
Sat Oct 10, 2020 16:38
An analysis of totally implantable central venous port system infections in an urban tertiary referral center. J Chemother. 2020 Oct 08;:1-10 Authors: Krümpelmann U, Boseila A, Löhnert M, Kaup O, Clarenbach JJ, Görner M Abstract A frequent complication of central venous port systems (CVP) is infection (CVP-I), either local (CVP-LI) or a life-threatening blood stream infection (CVP-BSI). We examined the course of CVP-I including results of an...
Fri Oct 09, 2020 16:36
A new hybrid immunocapture bioassay with improved reproducibility to measure tissue factor-dependent procoagulant activity of microvesicles from body fluids. Thromb Res. 2020 Sep 21;196:414-424 Authors: Franco C, Lacroix R, Vallier L, Judicone C, Bouriche T, Laroumagne S, Astoul P, Dignat-George F, Poncelet P Abstract BACKGROUND: The procoagulant activity of tissue factor-bearing microvesicles (MV-TF) has been associated with the risk of developing...
Sun Oct 11, 2020 13:32
Focal adhesion kinase: Insight into its roles and therapeutic potential in oesophageal cancer. Cancer Lett. 2020 Oct 07;: Authors: Zhang Y, Liu S, Zhou S, Yu D, Gu J, Qin Q, Cheng Y, Sun X Abstract Oesophageal cancer is associated with high morbidity and mortality rates because it is highly invasive and prone to recurrence and metastasis, with a five-year survival rate of <20%. Therefore, there is an urgent need for new methods aimed at...
Sun Oct 11, 2020 13:32
Older adult perspectives on medical decision making and emergency general surgery: "It had to be done." J Pain Symptom Manage. 2020 Oct 07;: Authors: Sokas C, Yeh IM, Coogan K, Bernacki R, Mitchell S, Bader A, Ladin K, Palmer JA, Tulsky JA, Cooper Z Abstract CONTEXT: Optimal surgical care for older adults with life-threatening conditions, with high risk of poor perioperative outcomes and morality in the months after surgery, should incorporate...
Sun Oct 11, 2020 13:32
Prophylaxis of thromboembolism during therapy with asparaginase in adults with acute lymphoblastic leukaemia. Cochrane Database Syst Rev. 2020 Oct 10;10:CD013399 Authors: Rank CU, Lynggaard LS, Als-Nielsen B, Stock W, Toft N, Nielsen OJ, Frandsen TL, Tuckuviene R, Schmiegelow K Abstract BACKGROUND: The risk of venous thromboembolism is increased in adults and enhanced by asparaginase-based chemotherapy, and venous thromboembolism introduces...
Sun Oct 11, 2020 13:32
Clinical impact of hypothalamic-pituitary disorders after conformal radiation therapy for pediatric low-grade glioma or ependymoma. Pediatr Blood Cancer. 2020 Oct 10;:e28723 Authors: van Iersel L, van Santen HM, Potter B, Li Z, Conklin HM, Zhang H, Chemaitilly W, Merchant TE Abstract BACKGROUND: To determine the impact of hypothalamic-pituitary (HP) disorders on health outcomes in children and adolescents who received conformal radiation therapy...
Sun Oct 11, 2020 13:32
The role of psychosocial support in the experiences of people living with advanced cancer: a qualitative exploration of patients' perspectives. Psychooncology. 2020 Oct 10;: Authors: Newton JC, O'Connor M, Saunders C, Moorin R, Ali S, Nowak AK, Halkett GK Abstract BACKGROUND: People living with advanced cancer experience significant distress and reduced quality of life due to their symptom burden and life-limiting prognosis. Limited qualitative...
Sun Oct 11, 2020 13:32
Robotic interval debulking surgery for advanced epithelial ovarian cancer: current challenge or future direction? A systematic review. J Robot Surg. 2020 Oct 09;: Authors: Psomiadou V, Prodromidou A, Fotiou A, Lekka S, Iavazzo C Abstract We evaluated the effectiveness, safety and efficacy of robotic interval debulking surgery (IDS) in advanced epithelial ovarian cancer (EOC) treated with neoadjuvant chemotherapy (NACT). We conducted a systematic...
Sun Oct 11, 2020 13:32
Adjuvant and neoadjuvant therapy for biliary tract cancer: a review of clinical trials. Jpn J Clin Oncol. 2020 Oct 10;: Authors: Nara S, Esaki M, Ban D, Takamoto T, Shimada K, Ioka T, Okusaka T, Ishii H, Furuse J Abstract Cancer originating in the biliary tract can be classified as bile duct cancer (cholangiocarcinoma), gallbladder cancer, or ampullary cancer. Bile duct cancer is further divided to intrahepatic, perihilar and distal bile duct...
Sun Oct 11, 2020 13:32
Feasibility of upfront mobile money transfers for transportation reimbursement to promote retention among patients receiving lymphoma treatment in Malawi. Int Health. 2020 Oct 09;: Authors: Ellis GK, Manda A, Topazian H, Stanley CC, Seguin R, Minnick CE, Tewete B, Mtangwanika A, Chawinga M, Chiyoyola S, Chikasema M, Salima A, Kimani S, Kasonkanji E, Mithi V, Kaimila B, Painschab MS, Gopal S, Westmoreland KD Abstract BACKGROUND: Cancer outcomes...
Sun Oct 11, 2020 13:32
Systemic and respiratory T-cells induced by seasonal H1N1 influenza protect against pandemic H2N2 in ferrets. Commun Biol. 2020 Oct 09;3(1):564 Authors: van de Ven K, de Heij F, van Dijken H, Ferreira JA, de Jonge J Abstract Traditional influenza vaccines primarily induce a narrow antibody response that offers no protection against heterosubtypic infections. Murine studies have shown that T cells can protect against a broad range of influenza...
Sun Oct 11, 2020 13:32
Demystifying the manipulation of host immunity, metabolism, and extraintestinal tumors by the gut microbiome. Signal Transduct Target Ther. 2019 Oct 12;4(1):41 Authors: Zhang Z, Tang H, Chen P, Xie H, Tao Y Abstract The trillions of microorganisms in the gut microbiome have attracted much attention recently owing to their sophisticated and widespread impacts on numerous aspects of host pathophysiology. Remarkable progress in large-scale sequencing...
Sun Oct 11, 2020 13:32
Evolving impact of long-term survival results on metastatic melanoma treatment. J Immunother Cancer. 2020 Oct;8(2): Authors: Michielin O, Atkins MB, Koon HB, Dummer R, Ascierto PA Abstract Melanoma treatment has been revolutionized over the past decade. Long-term results with immuno-oncology (I-O) agents and targeted therapies are providing evidence of durable survival for a substantial number of patients. These results have prompted consideration...
Sun Oct 11, 2020 13:32
Trends in urologic oncology clinical practice and medical education under COVID-19 pandemic: An international survey of senior clinical and academic urologists. Urol Oncol. 2020 Oct 06;: Authors: Rosenzweig B, Bex A, Dotan ZA, Frydenberg M, Klotz L, Lotan Y, Schulman CC, Tsaur I, Ramon J Abstract OBJECTIVE: Ad-hoc guidelines for managing the COVID-19 pandemic are published worldwide. We investigated international applications of such policies...
Sun Oct 11, 2020 13:32
Cerium Oxide Nanoparticles (Nanoceria): Hopes in Soft Tissue Engineering. Molecules. 2020 Oct 06;25(19): Authors: Sadidi H, Hooshmand S, Ahmadabadi A, Javad Hosseini S, Baino F, Vatanpour M, Kargozar S Abstract Several biocompatible materials have been applied for managing soft tissue lesions; cerium oxide nanoparticles (CNPs, or nanoceria) are among the most promising candidates due to their outstanding properties, including antioxidant, anti-inflammatory,...
Sun Oct 11, 2020 13:32
Patient and caregiver agreement on prognosis estimates for older adults with advanced cancer. Cancer. 2020 Oct 09;: Authors: Loh KP, Soto-Perez-de-Celis E, Duberstein PR, Culakova E, Epstein RM, Xu H, Kadambi S, Flannery M, Magnuson A, McHugh C, Trevino KM, Tuch G, Ramsdale E, Yousefi-Nooraie R, Sedenquist M, Liu JJ, Melnyk N, Geer J, Mohile SG Abstract BACKGROUND: Disagreements between patients and caregivers about treatment benefits, care...
Sat Oct 10, 2020 13:55
Were clinical routines for good end-of-life care maintained in hospitals and nursing homes during the first three months of the outbreak of COVID-19? A national register study. J Pain Symptom Manage. 2020 Oct 06;: Authors: Martinsson L, Strang P, Bergström J, Lundström S Abstract CONTEXT: Although the COVID-19 pandemic might affect important clinical routines, few studies have focused on the maintenance of good quality in end-of-life care....
Sat Oct 10, 2020 13:55
Sustainability of a rural volunteer program (Nav-CARE): a case study. Rural Remote Health. 2020 Oct;20(4):6112 Authors: Duggleby W, Pesut B, Warner G, Nekolaichuk C, Hallstrom LK, Elliott B, Swindle J, Ghosh S Abstract INTRODUCTION: Nav-CARE (Navigation: Connecting, Accessing, Resourcing and Engaging) is an evidence-based program that was implemented over 1 year in a rural community in western Canada. Nav-CARE uses volunteers who are trained...
Sat Oct 10, 2020 13:55
[Prognostic significance of invasion in glioblastoma]. Ideggyogy Sz. 2020 Sep 30;73(9-10):317-325 Authors: Szivós L, Virga J, Hortobágyi T, Zahuczky G, Uray I, Jenei A, Bognár L, Árkosy P, Klekner Á Abstract Background and purpose: Glioblastoma is the most common malignant CNS tumor, its surgical removal is hindered by the tumors invasive nature, while current anti-tumor therapies show limited effectiveness - mean overall survival is 16-24...
Sat Oct 10, 2020 13:55
Digitally Quantified CD8+ Cells - The Best Candidate Marker for an Immune Cell Score in NSCLC? Carcinogenesis. 2020 Oct 09;: Authors: Kilvaer TK, Paulsen EE, Andersen S, Rakaee M, Bremnes RM, Busund LR, Donnem T Abstract The TNM classification is well established as a state-of-the-art prognostic and treatment-decision-making tool for NSCLC patients. However, incorporation of biological data may hone the TNM system. This paper focuses on choosing...
Sat Oct 10, 2020 13:55
Assessing Immunotherapy with Functional and Molecular Imaging and Radiomics. Radiographics. 2020 Oct 09;:200070 Authors: García-Figueiras R, Baleato-González S, Luna A, Muñoz-Iglesias J, Oleaga L, Vallejo Casas JA, Martín-Noguerol T, Broncano J, Areses MC, Vilanova JC Abstract Immunotherapy is changing the treatment paradigm for cancer and has introduced new challenges in medical imaging. Because not all patients benefit from immunotherapy,...
Sat Oct 10, 2020 13:55
What is the future of patient reported outcomes in sickle cell disease? Expert Rev Hematol. 2020 Oct 09;: Authors: Singh SA, Bakshi N, Mahajan P, Morris CR Abstract INTRODUCTION: Sickle cell disease (SCD) is a complex, chronic disease caused by abnormal polymerization of hemoglobin, which leads to severe pain episodes, fatigue, and end-organ damage. Patient reported outcomes (PROs) have emerged as a critical tool for measuring SCD disease severity...
Sat Oct 10, 2020 13:55
Pemigatinib, a potent inhibitor of FGFRs for the treatment of cholangiocarcinoma. Future Oncol. 2020 Oct 09;: Authors: Merz V, Zecchetto C, Melisi D Abstract The prognosis of patients affected by cholangiocarcinoma is classically poor. Until recently, chemotherapeutic drugs were the only systemic treatment option available, leading to an overall survival lower than 1 year. In recent decades, different genetic alterations have been identified...
Sat Oct 10, 2020 13:55
Primary caregiver decision-making in hematopoietic cell transplantation and gene therapy for sickle cell disease. Pediatr Blood Cancer. 2020 Oct 08;:e28749 Authors: Sinha CB, Bakshi N, Ross D, Loewenstein G, Krishnamurti L Abstract BACKGROUND: Improved outcomes and the availability of clinical trials of hematopoietic cell transplantation (HCT) from alternate donors and genetically modified autologous hematopoietic progenitor cells have expanded...
Sat Oct 10, 2020 13:55
The impact of proton therapy on cardiotoxicity following radiation treatment. J Thromb Thrombolysis. 2020 Oct 08;: Authors: Frankart AJ, Nagarajan R, Pater L Abstract Cardiac disease following radiation therapy represents a major consideration in the treatment of a variety of malignancies. Damage to the heart can manifest in a variety of pathologies including ischemic cardiac disease, cardiomyopathy, valvular dysfunction, arrhythmias, and pericarditis....
Sat Oct 10, 2020 13:55
Medical affairs post-COVID 19: Are we ready to take the baton? Perspect Clin Res. 2020 Jul-Sep;11(3):124-127 Authors: Rajadhyaksha VD Abstract The spread of coronavirus epidemic has resulted in a change in the work schedule for Medical affairs professionals in the pharmaceutical industry. There has been an increase in virtual scientific interactions and prioritization of scientific communication. In the long term, this is likely to affect the...
Sat Oct 10, 2020 13:55
O-6-methylguanine DNA methyltransferase is a favorable biomarker with proliferation suppressive potential in Breast Cancer. J Cancer. 2020;11(21):6326-6336 Authors: Lin D, Xiao Y, Huang B, Wu X, Chen C, Liang Y, Zeng Abstract Background: The O6-methylguanine-DNA methyltransferase (MGMT) is a highly effective enzyme capable of repairing DNA damage to maintain genomic stability. Until recently, reports on the expression and potential role of...
Sat Oct 10, 2020 13:55
Combined inhibition of SHP2 and MEK is effective in models of NF1-deficient malignant peripheral nerve sheath tumors. Cancer Res. 2020 Oct 08;: Authors: Wang J, Pollard K, Allen AN, Tomar T, Pijnenburg D, Yao Z, Rodriguez FJ, Pratilas CA Abstract Loss of the RAS GTPase-activating protein (RAS-GAP) NF1 drives aberrant activation of RAS/MEK/ERK signaling and other effector pathways in the majority of malignant peripheral nerve sheath tumors (MPNST)....
Sat Oct 10, 2020 13:55
Prevalence and predictors of patients reporting adverse drug reactions to health care providers during oral targeted cancer treatment. J Am Pharm Assoc (2003). 2020 Oct 05;: Authors: Monestime S, Page R, Jordan WM, Aryal S Abstract BACKGROUND: Pharmacovigilance is a critical component to facilitate clinicians' decision-making to alter or discontinue therapy. However, self-administration of oral targeted therapy (OTT) requires fewer clinical...
Sat Oct 10, 2020 13:55
The readability of online Canadian radiotherapy patient educational materials. J Med Imaging Radiat Sci. 2020 Oct 05;: Authors: Al Balushi M, Ghosh S, Debenham B Abstract INTRODUCTION/BACKGROUND: It is not clear if online radiotherapy patient educational materials that are published by the Canadian Cancer Society (CCS) and the various provincial health authorities meet the appropriate readability levels. The aim of this study is to determine...
Sat Oct 10, 2020 13:55
Molecular events in the pathogenesis of vulvar squamous cell carcinoma. Semin Diagn Pathol. 2020 Sep 25;: Authors: Xing D, Fadare O Abstract Vulvar squamous cell carcinomas (VSCC), which constitute over 90% of vulvar malignancies in adults, are classifiable into 2 subgroups that are mostly clinicopathologically distinct, a classification that is fundamentally based whether or not the tumors are HPV-mediated. In this review, we aim to summarize...
Sat Oct 10, 2020 13:55
Cholangiocarcinoma miscoding in hepatobiliary centres. Eur J Surg Oncol. 2020 Oct 01;: Authors: Selvadurai S, Mann K, Mithra S, Bridgewater J, Malik H, Khan SA Abstract INTRODUCTION: Cholangiocarcinoma (CCA) are sub-divided into intrahepatic (iCCA) or extrahepatic (eCCA). eCCA are further subdivided into perihilar (pCCA) and distal (dCCA). Current and previous versions of the WHO International Coding of Disease and Oncology classifications...
Sat Oct 10, 2020 13:55
Beyond Deterministic Models in Drug Discovery and Development. Trends Pharmacol Sci. 2020 Oct 05;: Authors: Irurzun-Arana I, Rackauckas C, McDonald TO, Trocóniz IF Abstract The model-informed drug discovery and development paradigm is now well established among the pharmaceutical industry and regulatory agencies. This success has been mainly due to the ability of pharmacometrics to bring together different modeling strategies, such as population...
Sat Oct 10, 2020 13:55
Experiences of awake surgery in non-tumoural epilepsy in eloquent localizations. Clin Neurol Neurosurg. 2020 Sep 25;199:106251 Authors: Vigren P, Eriksson M, Duffau H, Wretman A, Lindehammar H, Milos P, Richter J, Karlsson T, Gauffin H Abstract BACKGROUND: Whilst modern awake intraoperative mapping has been widely accepted and implemented in the last decades in neuro-oncology, sparse reports have been published on the safety and efficiency...
Fri Oct 09, 2020 14:06
Anticipating the future of the child and family in pediatric palliative care: a qualitative study into the perspectives of parents and healthcare professionals. Eur J Pediatr. 2020 Oct 08;: Authors: Verberne LM, Fahner JC, Sondaal SFV, Schouten-van Meeteren AYN, de Kruiff CC, van Delden JJM, Kars MC Abstract Preparing for future scenarios in pediatric palliative care is perceived as complex and challenging by both families and healthcare professionals....
Fri Oct 09, 2020 14:06
MyPref: pilot study of a novel communication and decision-making tool for adolescents and young adults with advanced cancer. Support Care Cancer. 2020 Oct 08;: Authors: Snaman JM, Helton G, Holder RL, Wittenberg E, Revette A, Tulsky JA, Baker JN, Wolfe J Abstract PURPOSE: Adolescents and young adults (AYAs) with cancer report feeling ill-informed about their cancer treatment options. Tools are needed to inform AYAs about treatment choices and...
Fri Oct 09, 2020 14:06
Producing a Beam Model of the Varian ProBeam Proton Therapy System using TOPAS Monte Carlo Toolkit. Med Phys. 2020 Oct 08;: Authors: Rahman M, Bruza P, Lin Y, Gladstone DJ, Pogue BW, Zhang R Abstract PURPOSE: A Geant4-based TOPAS Monte Carlo toolkit was utilized to model a Varian ProBeam proton therapy system, with the aim of providing an independent computational platform for validating advanced dosimetric methods. MATERIALS AND METHODS:...
Fri Oct 09, 2020 14:06
Poor Psychosocial Well-Being in the First Year-and-a-Half After Losing a Parent to Cancer - A Longitudinal Study Among Young Adults Participating in Support Groups. J Soc Work End Life Palliat Care. 2020 Oct 08;:1-16 Authors: Lundberg T, Forinder U, Olsson M, Fürst CJ, Årestedt K, Alvariza A Abstract The purpose of this study was to investigate variations in psychosocial well-being over time among young adults who participated in a support...
Fri Oct 09, 2020 14:06
Clinical Pharmacokinetics and Pharmacodynamics of the Cyclin-Dependent Kinase 4 and 6 Inhibitors Palbociclib, Ribociclib, and Abemaciclib. Clin Pharmacokinet. 2020 Oct 08;: Authors: Groenland SL, Martínez-Chávez A, van Dongen MGJ, Beijnen JH, Schinkel AH, Huitema ADR, Steeghs N Abstract Palbociclib, ribociclib, and abemaciclib are inhibitors of the cyclin-dependent kinases 4 and 6 approved for the treatment of locally advanced or metastatic...
Fri Oct 09, 2020 14:06
Targeted Therapies in the Management of Well-Differentiated Digestive and Lung Neuroendocrine Neoplasms. Curr Treat Options Oncol. 2020 Oct 07;21(12):96 Authors: Vijayvergia N, Dasari A Abstract OPINION STATEMENT: Ongoing advances in our understanding of neuroendocrine tumor (NET) biology, genetics, and immunology, will continue to expand the availability of targeted therapies, thus improving the outcomes of patients. Well-differentiated neuroendocrine...
Fri Oct 09, 2020 14:06
Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer. BMC Cancer. 2020 Oct 07;20(1):970 Authors: Hoover AA, Hufnagel DH, Harris W, Bullock K, Glass EB, Liu E, Barham W, Crispens MA, Khabele D, Giorgio TD, Wilson AJ, Yull FE Abstract BACKGROUND: New treatment options for ovarian cancer are urgently required. Tumor-associated macrophages (TAMs)...
Fri Oct 09, 2020 14:06
Exploratory analysis of the platelet-to-lymphocyte ratio prognostic value in the adjuvant renal cell cancer setting. Future Oncol. 2020 Oct 08;: Authors: Patel A, Ravaud A, Motzer RJ, Pantuck AJ, Staehler M, Escudier B, Martini JF, Lechuga M, Lin X, George DJ Abstract Aim: To examine the prognostic value of the platelet-to-lymphocyte ratio (PLR) in the adjuvant renal cell carcinoma setting. Materials & methods: Patients received adjuvant...
Fri Oct 09, 2020 14:06
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