Cells, Vol. 8, Pages 751: HLA-DQA1 and HLA-DQB1 Alleles, Conferring Susceptibility to Celiac Disease and Type 1 Diabetes, are More Expressed Than Non-Predisposing Alleles and are Coordinately Regulated Cells doi: 10.3390/cells8070751 Authors: Farina Picascia Pisapia Barba Vitale Franzese Mozzillo Gianfrani Del Pozzo G HLA DQA1*05 and DQB1*02 alleles encoding the DQ2.5 molecule and HLA DQA1*03 and DQB1*03 alleles encoding DQ8 molecules are strongly associated...
Cells, Vol. 8, Pages 750: Autoantibodies Specific to ERα are Involved in Tamoxifen Resistance in Hormone Receptor Positive Breast Cancer Cells doi: 10.3390/cells8070750 Authors: Angela Maselli Stefania Parlato Rossella Puglisi Carla Raggi Massimo Spada Daniele Macchia Giada Pontecorvi Elisabetta Iessi Maria Teresa Pagano Francesca Cirulli Lucia Gabriele Alessandra Carè Patrizia Vici Laura Pizzuti Maddalena Barba Paola Matarrese Marina Pierdominici...
Cells, Vol. 8, Pages 753: Annexin A1 Contained in Extracellular Vesicles Promotes the Activation of Keratinocytes by Mesoglycan Effects: An Autocrine Loop Through FPRs Cells doi: 10.3390/cells8070753 Authors: Pessolano Belvedere Bizzarro Franco Marco Petrella Porta Tosco Parente Perretti Petrella We have recently demonstrated that mesoglycan, a fibrinolytic compound, may be a promising pro-healing drug for skin wound repair. We showed that mesoglycan...
Pharmaceutics, Vol. 11, Pages 352: Inhaled Antibiotics for Mycobacterial Lung Disease Pharmaceutics doi: 10.3390/pharmaceutics11070352 Authors: Banaschewski Hofmann Mycobacterial lung diseases are an increasing global health concern. Tuberculosis and nontuberculous mycobacteria differ in disease severity, epidemiology, and treatment strategies, but there are also a number of similarities. Pathophysiology and disease progression appear to be relatively similar between these two clinical...
Viruses, Vol. 11, Pages 664: The Needs for Developing Experiments on Reservoirs in Hantavirus Research: Accomplishments, Challenges and Promises for the Future Viruses doi: 10.3390/v11070664 Authors: Madrières Castel Murri Vulin Marianneau Charbonnel Due to their large geographic distribution and potential high mortality rates in human infections, hantaviruses constitute a worldwide threat to public health. As such, they have been the subject of a large array of...
Biomolecules, Vol. 9, Pages 291: Alginate Gel Reinforcement with Chitin Nanowhiskers Modulates Rheological Properties and Drug Release Profile Biomolecules doi: 10.3390/biom9070291 Authors: Valentina A. Petrova Vladimir Y. Elokhovskiy Sergei V. Raik Daria N. Poshina Dmitry P. Romanov Yury A. Skorik Hydrogels are promising materials for various applications, including drug delivery, tissue engineering, and wastewater treatment. In this work, we designed an alginate (ALG)...
Environments, Vol. 6, Pages 84: Potential Impacts to Wetlands and Water Bodies Due to Mineral Exploration, Pebble Copper-Gold Prospect, Southwest Alaska Environments doi: 10.3390/environments6070084 Authors: Zamzow Chambers There is little information in the literature about the impacts of mineral exploration drilling on natural waters. A copper-gold-molybdenum mining deposit in Alaska was heavily explored until 2012 and partially reclaimed; however, full reclamation of drill sites...
IJERPH, Vol. 16, Pages 2588: Detection of Hepatitis A Virus and Other Enteric Viruses in Shellfish Collected in the Gulf of Naples, Italy International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16142588 Authors: Fusco Anastasio Kingsley Amoroso Pepe Fratamico Cioffi Rossi Rosa Boccia To assess the quality of shellfish harvest areas, bivalve mollusk samples from three coastal areas of the Campania region in Southwest Italy...
Atmosphere, Vol. 10, Pages 417: Virus-Like Particle Production in Atmospheric Eubacteria Isolates Atmosphere doi: 10.3390/atmos10070417 Authors: Teigell-Perez Gonzalez-Martin Valladares Smith Griffin Culturable eubacterial isolates were collected at various altitudes in Earth’s atmosphere, including ~1.5 m above ground in Tallahassee, FL, USA; ~10.0 m above sea level over the mid-Atlantic ridge (~15° N); ~ 20 km above ground over the continental United...
Atmosphere, Vol. 10, Pages 416: No Significant Shift of Warming Trend over the Last Two Decades on the Mid-South of Tibetan Plateau Atmosphere doi: 10.3390/atmos10070416 Authors: Li Zhang Qi Wang Liu Ding Climate warming on the Tibetan Plateau has been regarded as an important driving force of regional environmental change. Although several studies have analyzed the shift of warming trends on this plateau within the context of a recent global warming “hiatus”...
Foods, Vol. 8, Pages 269: Prevalence and toxicity characterization of Bacillus cereus in food products from Poland Foods doi: 10.3390/foods8070269 Authors: Berthold-Pluta Pluta Garbowska Stefańska The prevalence of Bacillus cereus in a total of 585 samples of food products (herbs and spices, breakfast cereals, pasta, rice, infant formulas, pasteurized milk, fresh acid and acid/rennet cheeses, mold cheeses and ripening rennet cheeses) marketed in Poland was investigated....
Foods, Vol. 8, Pages 270: Factors Predicting the Intention of Eating an Insect-Based Product Foods doi: 10.3390/foods8070270 Authors: Simone Mancini Giovanni Sogari Davide Menozzi Roberta Nuvoloni Beatrice Torracca Roberta Moruzzo Gisella Paci This study provides a framework of the factors predicting the intention of eating an insect-based product. As part of the study, a seminar was carried out to explore how the provision of information about ecological, health, and...
Risks, Vol. 7, Pages 82: Loss Reserving Models: Granular and Machine Learning Forms Risks doi: 10.3390/risks7030082 Authors: Taylor The purpose of this paper is to survey recent developments in granular models and machine learning models for loss reserving, and to compare the two families with a view to assessment of their potential for future development. This is best understood against the context of the evolution of these models from their predecessors, and the early sections recount...
Molecules, Vol. 24, Pages 2635: Chiral Recognition of Carboxylate Anions by (R)-BINOL-Based Macrocyclic Receptors Molecules doi: 10.3390/molecules24142635 Authors: Tyszka-Gumkowska Pikus Jurczak Three (R)-BINOL-based macrocyclic receptors obtained via double-amidation reaction were used for chiral recognition of four anions derived from α-hydroxy and α-amino acids. The structural factors of hosts and guests that affect chiral recognition processes were also...
Molecules, Vol. 24, Pages 2634: Alkene Difunctionalization Using Hypervalent Iodine Reagents: Progress and Developments in the Past Ten Years Molecules doi: 10.3390/molecules24142634 Authors: Lee Choi Hong Hypervalent iodine reagents are of considerable relevance in organic chemistry as they can provide a complementary reaction strategy to the use of traditional transition metal chemistry. Over the past two decades, there have been an increasing number of applications including...
Molecules, Vol. 24, Pages 2636: Multicomponent Synthesis of Polyphenols and their in vitro Evaluation as Potential β-Amyloid Aggregation Inhibitors Molecules doi: 10.3390/molecules24142636 Authors: Galante Banfi Baruzzo Basso D’Arrigo Lunaccio Moni Riva Lambruschini While plant polyphenols possess a variety of biological properties, exploration of chemical diversity around them is still problematic. Here, an example of application of the Ugi multicomponent...
IJMS, Vol. 20, Pages 3548: Plasticity of High-Density Neutrophils in Multiple Myeloma is Associated with Increased Autophagy via STAT3 International Journal of Molecular Sciences doi: 10.3390/ijms20143548 Authors: Puglisi Parrinello Giallongo Cambria Camiolo Bellofiore Conticello Fabro Leotta Markovic Sapienza Barbato Scalese Tibullo Brundo Palumbo * Romano In both monoclonal gammopathy of uncertain significance (MGUS)...
IJMS, Vol. 20, Pages 3549: Promoting Beneficial and Inhibiting Undesirable Biofilm Formation with Mangrove Extracts International Journal of Molecular Sciences doi: 10.3390/ijms20143549 Authors: Glasenapp Cattò Villa Saracchi Cappitelli Papenbrock The extracts of two mangrove species, Bruguiera cylindrica and Laguncularia racemosa, have been analyzed at sub-lethal concentrations for their potential to modulate biofilm cycles (i.e., adhesion, maturation, and detachment)...
Water, Vol. 11, Pages 1500: Data-Driven Approach for Leak Localization in Water Distribution Networks Using Pressure Sensors and Spatial Interpolation Water doi: 10.3390/w11071500 Authors: Adrià Soldevila Joaquim Blesa Rosa M. Fernandez-Canti Sebastian Tornil-Sin Vicenç Puig This paper presents a new data-driven method for leak localization in water distribution networks. The proposed method relies on the use of available pressure measurements in some selected internal network...
Water, Vol. 11, Pages 1501: Pluvial Flooding in Utrecht: On Its Way to a Flood-Proof City Water doi: 10.3390/w11071501 Authors: Brockhoff Koop Snel Downpours are increasing in frequency and severity due to climate change. Cities are particularly susceptible to flooding from downpours because of their large share of impervious surfaces. Minimising pluvial flood risk requires all involved stakeholders to collaborate and overcome various barriers. Although an increase in citizen...
Nutrients, Vol. 11, Pages 1657: Differential Stimulation of Post-Exercise Myofibrillar Protein Synthesis in Humans Following Isonitrogenous, Isocaloric Pre-Exercise Feeding Nutrients doi: 10.3390/nu11071657 Authors: Robert W. Davies Joseph J. Bass Brian P. Carson Catherine Norton Marta Kozior Miryam Amigo-Benavent Daniel J. Wilkinson Matthew S. Brook Philip J. Atherton Kenneth Smith Philip M. Jakeman The aim of this study was to test the effects of two disparate...
Medicina, Vol. 55, Pages 390: Affective Temperaments and Clinical Course of Bipolar Disorder: An Exploratory Study of Differences among Patients with and without a History of Violent Suicide Attempts Medicina doi: 10.3390/medicina55070390 Authors: Fico Caivano Zinno Carfagno Steardo Sampogna Luciano Fiorillo Background and Objectives: Suicide is the leading cause of death in patients with Bipolar Disorder (BD). In particular, the high mortality rate is due...
Medicina, Vol. 55, Pages 389: A New ABCA3 Gene Mutation c.3445G>A (p.Asp1149Asn) as a Causative Agent of Newborn Lethal Respiratory Distress Syndrome Medicina doi: 10.3390/medicina55070389 Authors: Mitsiakos Tsakalidis Karagianni Gialamprinou Chatziioannidis Papoulidis Tsanakas Soubasi Mutations in adenosine triphosphate-binding cassette transporter A3 (ABCA3) (OMIM: 601615) gene constitute the most frequent genetic cause of severe neonatal respiratory...
IJMS, Vol. 20, Pages 3547: Transcriptome Analysis Did Not Show Endogenous Stem Cell Characteristics in Murine Lgr5+ Retinal Cells International Journal of Molecular Sciences doi: 10.3390/ijms20143547 Authors: Carolyn Trepp Ana Maria Quintela Pousa Volker Enzmann Lgr5, an intestinal adult stem cell marker, was recently also found in neuronal tissues. We investigated whether retinal Lgr5+ cells express properties of neural stem cells (NSC) and/or of differentiated interneurons during...
IJERPH, Vol. 16, Pages 2587: Contributions of Indoor and Outdoor Sources to Ozone in Residential Buildings in Nanjing International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16142587 Authors: Yu Huang Zhe Yang Zhi Gao Ozone has become one of the most serious air pollutants in China in recent years. Since people spend most of their time indoors, the ozone in the indoor environment could be a major factor affecting the occupants’ health. The...
Toxins, Vol. 11, Pages 423: Ciguatera-Causing Dinoflagellate Gambierdiscus spp. (Dinophyceae) in a Subtropical Region of North Atlantic Ocean (Canary Islands): Morphological Characterization and Biogeography Toxins doi: 10.3390/toxins11070423 Authors: Isabel Bravo Francisco Rodriguez Isabel Ramilo Pilar Rial Santiago Fraga Dinoflagellates belonging to the genus Gambierdiscus produce ciguatoxins (CTXs), which are metabolized in fish to more toxic forms and subsequently cause...
JCM, Vol. 8, Pages 1063: Best Evidence Rehabilitation for Chronic Pain Part 3: Low Back Pain Journal of Clinical Medicine doi: 10.3390/jcm8071063 Authors: Malfliet Ickmans Huysmans Coppieters Willaert Bogaert Rheel Bilterys Wilgen Nijs Chronic Low Back Pain (CLBP) is a major and highly prevalent health problem. Given the high number of papers available, clinicians might be overwhelmed by the evidence on CLBP management. Taking into account the scale...
Cancers, Vol. 11, Pages 1013: WNT Signaling in Neuroblastoma Cancers doi: 10.3390/cancers11071013 Authors: Juergen Becker Joerg Wilting The term WNT (wingless-type MMTV integration site family) signaling comprises a complex molecular pathway consisting of ligands, receptors, coreceptors, signal transducers and transcriptional modulators with crucial functions during embryonic development, including all aspects of proliferation, morphogenesis and differentiation. Its involvement in...
Molbank, Vol. 2019, Article M1074: 4-[(3,5-Dimethyl-1H-pyrazol-1-yl)methyl]-4-methyl-2-phenyl-4,5-dihydrooxazole Molbank doi: 10.3390/M1074 Authors: Hajib Alami Faraj Aouine The compound, 4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-4-methyl-2-phenyl-4,5-dihydrooxazole 2 was prepared in high yield, through nucleophilic substitution reaction of the O-tosyl oxazoline derivative 1, by heating in dimethyl sulfoxide (DMSO) and in presence of KOH as base. The structure of the synthesized...
JFMK, Vol. 4, Pages 45: Correlations between Malocclusion and Postural Anomalies in Children with Mixed Dentition Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk4030045 Authors: Sambataro Bocchieri Cervino Bruna Cicciù Innorta Torrisi Cicciù The aim of this study was to investigate the possible relationship between malocclusion and body posture anomalies. The original sample involved 127 children (45 males and 82 females) with mixed dentition....
JoF, Vol. 5, Pages 66: The Burden of Serious Fungal Infections in Kyrgyzstan Journal of Fungi doi: 10.3390/jof5030066 Authors: Turdumambetova Osmanov Denning : Kyrgyzstan in Central Asia has a population of 6 million people who have high mortality rates for chronic lung diseases. The mountainous geography, widespread use of biomass fuels for cooking and indoor heating, and high rates of smoking are the major contributing factors. We have estimated the number of serious fungal...
Cells, Vol. 8, Pages 748: Golgi Fragmentation in Neurodegenerative Diseases: Is There a Common Cause? Cells doi: 10.3390/cells8070748 Authors: José Ángel Martínez-Menárguez Mónica Tomás Narcisa Martínez-Martínez Emma Martínez-Alonso In most mammalian cells, the Golgi complex forms a continuous ribbon. In neurodegenerative diseases, the Golgi ribbon of a specific group of neurons is typically broken into isolated elements, a very early event which happens before clinical and...
Cells, Vol. 8, Pages 749: Dicarbonyl Stress at the Crossroads of Healthy and Unhealthy Aging Cells doi: 10.3390/cells8070749 Authors: Cecilia Nigro Alessia Leone Francesca Fiory Immacolata Prevenzano Antonella Nicolò Paola Mirra Francesco Beguinot Claudia Miele Dicarbonyl stress occurs when dicarbonyl metabolites (i.e., methylglyoxal, glyoxal and 3-deoxyglucosone) accumulate as a consequence of their increased production and/or decreased detoxification. This toxic...
Heritage, Vol. 2, Pages 2028-2038: X-Ray Computed Tomography In Situ: An Opportunity for Museums and Restoration Laboratories Heritage doi: 10.3390/heritage2030122 Authors: Fauzia Albertin Matteo Bettuzzi Rosa Brancaccio Maria Pia Morigi Franco Casali X-ray Computed Tomography (X-ray CT) is a sophisticated non-destructive imaging technique to investigate structures and materials of complex objects, and its application can answer many conservation and restoration questions....
Antioxidants, Vol. 8, Pages 231: Bioassay Directed Isolation, Biological Evaluation and in Silico Studies of New Isolates from Pteris cretica L. Antioxidants doi: 10.3390/antiox8070231 Authors: Saleem Mehmood Mehar Khan Khan Ashraf Ali Abdullah Froeyen Mirza Ahmad Members of genus Pteris have their established role in the traditional herbal medicine system. In the pursuit to identify its biologically active constituents, the specie Pteris cretica...
Nutrients, Vol. 11, Pages 1656: Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1/KDM1A Nutrients doi: 10.3390/nu11071656 Authors: Elisabet Cuyàs Juan Gumuzio Jesús Lozano-Sánchez David Carreras Sara Verdura Laura Llorach-Parés Melchor Sanchez-Martinez Elisabet Selga Guillermo J. Pérez Fabiana S. Scornik Ramon Brugada Joaquim Bosch-Barrera Antonio Segura-Carretero Ángel G. Martin José Antonio Encinar Javier A....
IJMS, Vol. 20, Pages 3546: Alteration of the Total Cellular Glycome during Late Differentiation of Chondrocytes International Journal of Molecular Sciences doi: 10.3390/ijms20143546 Authors: Kentaro Homan Hisatoshi Hanamatsu Jun-ichi Furukawa Kazue Okada Ikuko Yokota Tomohiro Onodera Norimasa Iwasaki In normal articular cartilage, chondrocytes do not readily proliferate or terminally differentiate, and exhibit a low level of metabolism. Hypertrophy-like changes of chondrocytes...
IJMS, Vol. 20, Pages 3545: Genomic Organization of Repetitive DNA Elements and Extensive Karyotype Diversity of Silurid Catfishes (Teleostei: Siluriformes): A Comparative Cytogenetic Approach International Journal of Molecular Sciences doi: 10.3390/ijms20143545 Authors: Sukhonthip Ditcharoen Luiz Antonio Carlos Bertollo Petr Ráb Eva Hnátková Wagner Franco Molina Thomas Liehr Alongklod Tanomtong Costas Triantaphyllidis Catherine Ozouf-Costaz Sampan Tongnunui Puan...
IJMS, Vol. 20, Pages 3543: Sex-Dimorphic Behavioral Alterations and Altered Neurogenesis in U12 Intron Splicing-Defective Zrsr1 Mutant Mice International Journal of Molecular Sciences doi: 10.3390/ijms20143543 Authors: Francisco Alén Isabel Gómez-Redondo Patricia Rivera Juan Suárez Priscila Ramos-Ibeas Eva Pericuesta Raul Fernández-González Serafín Perez-Cerezales Keiko Horiuchi Laura Orio Fernando Rodriguez de Fonseca Alfonso Gutiérrez-Adán Mutant mice...
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