Molecules, Vol. 24, Pages 2742: Aquaphotomics—From Innovative Knowledge to Integrative Platform in Science and Technology Molecules doi: 10.3390/molecules24152742 Authors: Jelena Muncan Roumiana Tsenkova Aquaphotomics is a young scientific discipline based on innovative knowledge of water molecular network, which as an intrinsic part of every aqueous system is being shaped by all of its components and the properties of the environment. With a high capacity for hydrogen bonding, water...
Sun Jul 28, 2019 03:00
Molecules, Vol. 24, Pages 2740: Polysaccharides from Basidiocarps of Cultivating Mushroom Pleurotus ostreatus: Isolation and Structural Characterization Molecules doi: 10.3390/molecules24152740 Authors: Ekaterina Baeva Roman Bleha Ekaterina Lavrova Leonid Sushytskyi Jana Čopíková Ivan Jablonsky Pavel Klouček Andriy Synytsya Oyster mushrooms are an interesting source of biologically active glucans and other polysaccharides. This work is devoted to the isolation and...
Sun Jul 28, 2019 03:00
Molecules, Vol. 24, Pages 2741: Melatonin Protects Band 3 Protein in Human Erythrocytes against H2O2-Induced Oxidative Stress Molecules doi: 10.3390/molecules24152741 Authors: Rossana Morabito Alessia Remigante Angela Marino The beneficial effect of Melatonin (Mel), recognized as an anti-inflammatory and antioxidant compound, has been already proven to prevent oxidative stress-induced damage associated to lipid peroxidation. As previous studies modeled the impact of oxidative stress...
Sun Jul 28, 2019 03:00
Molecules, Vol. 24, Pages 2739: Iridium(III) Complexes Targeting Apoptotic Cell Death in Cancer Cells Molecules doi: 10.3390/molecules24152739 Authors: Dik-Lung Ma Chun Wu Ke-Jia Wu Chung-Hang Leung Targeting apoptosis is a principal strategy in the design of anticancer drugs. In recent years, non-platinum-based scaffolds have been exploited as viable candidates for the exploitation of anticancer agents with potentially lower toxicity than the widely used cisplatin analogues....
Sun Jul 28, 2019 03:00
Molecules, Vol. 24, Pages 2738: Hardware Realization of the Pattern Recognition with an Artificial Neuromorphic Device Exhibiting a Short-Term Memory Molecules doi: 10.3390/molecules24152738 Authors: Dawid Przyczyna Maria Lis Kacper Pilarczyk Konrad Szaciłowski Materials exhibiting memory or those capable of implementing certain learning schemes are the basic building blocks used in hardware realizations of the neuromorphic computing. One of the common goals within this paradigm...
Sun Jul 28, 2019 03:00
Molecules, Vol. 24, Pages 2737: Allelochemicals and Signaling Chemicals in Plants Molecules doi: 10.3390/molecules24152737 Authors: Chui-Hua Kong Tran Dang Xuan Tran Dang Khanh Hoang-Dung Tran Nguyen Thanh Trung Plants abound with active ingredients. Among these natural constituents, allelochemicals and signaling chemicals that are released into the environments play important roles in regulating the interactions between plants and other organisms. Allelochemicals participate...
Sat Jul 27, 2019 03:00
Molecules, Vol. 24, Pages 2736: Four New ent-Kaurane Diterpene Glycosides from Isodon henryi Molecules doi: 10.3390/molecules24152736 Authors: Liu Zhang Wu Chen Li Dai Wang To obtain diterpene glycosides from an aqueous extract of the aerial parts of Isodon henryi and further investigate their cytotoxicities, in this study, a total of seven compounds were isolated, including six ent-kaurane diterpene glycosides (1–6) and one diterpene aglycon (7). Among...
Sat Jul 27, 2019 03:00
Molecules, Vol. 24, Pages 2733: Relationships between Interaction Energy and Electron Density Properties for Homo Halogen Bonds of the [(A)nY–X···X–Z(B)m] Type (X = Cl, Br, I) Molecules doi: 10.3390/molecules24152733 Authors: Maxim L. Kuznetsov Relationships between interaction energy (Eint) and electron density properties at the X···X bond critical point or the d(X···X) distance were established for the large set of structures...
Sat Jul 27, 2019 03:00
Molecules, Vol. 24, Pages 2734: Downscaling of Industrial Turbo-Distillation to Laboratory Turbo-Clevenger for Extraction of Essential Oils. Application of Concepts of Green Analytical Chemistry Molecules doi: 10.3390/molecules24152734 Authors: Sandrine Périno Zoubida Chemat-Djenni Emmanuel Petitcolas Christian Giniès Farid Chemat In the effort of innovation towards green analytical chemistry concepts and considering the six principles of green extraction, the industrial...
Sat Jul 27, 2019 03:00
Molecules, Vol. 24, Pages 2735: Site Selective and Efficient Spin Labeling of Proteins with a Maleimide-Functionalized Trityl Radical for Pulsed Dipolar EPR Spectroscopy Molecules doi: 10.3390/molecules24152735 Authors: J. Jacques Jassoy Caspar A. Heubach Tobias Hett Frédéric Bernhard Florian R. Haege Gregor Hagelueken Olav Schiemann Pulsed dipolar electron paramagnetic resonance spectroscopy (PDS) in combination with site-directed spin labeling (SDSL) of proteins and...
Sat Jul 27, 2019 03:00
Molecules, Vol. 24, Pages 2732: Prediction of Transformation Products of Monensin by Electrochemistry Compared to Microsomal Assay and Hydrolysis Molecules doi: 10.3390/molecules24152732 Authors: Lisa Kotthoff Jan Lisec Tanja Schwerdtle Matthias Koch The knowledge of transformation pathways and identification of transformation products (TPs) of veterinary drugs is important for animal health, food, and environmental matters. The active agent Monensin (MON) belongs to the ionophore...
Sat Jul 27, 2019 03:00
Molecules, Vol. 24, Pages 2731: Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage Molecules doi: 10.3390/molecules24152731 Authors: Khadijah Edueng Denny Mahlin Johan Gråsjö Olivia Nylander Manish Thakrani Christel A.S. Bergström This study explores the effect of physical aging and/or crystallization on the supersaturation potential and crystallization kinetics of amorphous active pharmaceutical ingredients (APIs). Spray-dried,...
Sat Jul 27, 2019 03:00
Molecules, Vol. 24, Pages 2730: A Rapid Chemiluminescence Assay for Measurement of Folate in Small Volumes of Breast Milk Molecules doi: 10.3390/molecules24152730 Authors: Laurence Guignard Chiara Nembrini Julie Moulin Karine Meisser Irma Silva-Zolezzi Jürgen Kratzsch Mandy Vogel Wieland Kiess Erik Eckhardt Early life exposure to folate has long lasting effects on development and health. Newborns obtain part of their folate from maternal milk. Studies on health...
Sat Jul 27, 2019 03:00
Molecules, Vol. 24, Pages 2729: Centrifugation Conditions in the L-PRP Preparation Affect Soluble Factors Release and Mesenchymal Stem Cell Proliferation in Fibrin Nanofibers Molecules doi: 10.3390/molecules24152729 Authors: Melo Luzo Lana Santana Leukocyte and platelet-rich plasma (L-PRP) is an autologous product that when activated forms fibrin nanofibers, which are useful in regenerative medicine. As an important part of the preparation of L-PRP, the centrifugation parameters...
Sat Jul 27, 2019 03:00
Molecules, Vol. 24, Pages 2727: Erianin Inhibits Proliferation and Induces Apoptosis of HaCaT Cells via ROS-Mediated JNK/c-Jun and AKT/mTOR Signaling Pathways Molecules doi: 10.3390/molecules24152727 Authors: Mo Shetti Wei Psoriasis is a recurrent skin disease described as keratinocyte hyperproliferation and aberrant differentiation. Erianin, a bibenzyl compound extracted from Dendrobium chrysotoxum, has displayed antitumor and anti-angiogenesis effects. However, the effects...
Fri Jul 26, 2019 03:00
Molecules, Vol. 24, Pages 2726: Diterpenoid Lactones with Anti-Inflammatory Effects from the Aerial Parts of Andrographis paniculata Molecules doi: 10.3390/molecules24152726 Authors: Lin Gan Yuanru Zheng Lijuan Deng Pinghua Sun Jiaxi Ye Xiduan Wei Feifei Liu Linzhong Yu Wencai Ye Chunlin Fan Junshan Liu Wenqing Zhang Andrographis paniculata (AP) has been widely used in China for centuries to treat various diseases, and especially to treat inflammation....
Fri Jul 26, 2019 03:00
Molecules, Vol. 24, Pages 2728: Characterization of a Cis-Prenyltransferase from Lilium longiflorum Anther Molecules doi: 10.3390/molecules24152728 Authors: Jyun-Yu Yao Kuo-Hsun Teng Ming-Che Liu Co-Shine Wang Po-Huang Liang A group of prenyltransferases catalyze chain elongation of farnesyl diphosphate (FPP) to designated lengths via consecutive condensation reactions with specific numbers of isopentenyl diphosphate (IPP). cis-Prenyltransferases, which catalyze cis-double...
Fri Jul 26, 2019 03:00
Molecules, Vol. 24, Pages 2725: Kinetic Processes in Amorphous Materials Revealed by Thermal Analysis: Application to Glassy Selenium Molecules doi: 10.3390/molecules24152725 Authors: Málek Svoboda It is expected that viscous flow is affecting the kinetic processes in a supercooled liquid, such as the structural relaxation and the crystallization kinetics. These processes significantly influence the behavior of glass being prepared by quenching. In this paper, the activation energy...
Fri Jul 26, 2019 03:00
Molecules, Vol. 24, Pages 2724: Discovery of (5-Phenylfuran-2-yl)methanamine Derivatives as New Human Sirtuin 2 Inhibitors Molecules doi: 10.3390/molecules24152724 Authors: Lijiao Wang Chao Li Wei Chen Chen Song Xing Zhang Fan Yang Chen Wang Yuanyuan Zhang Shan Qian Zhouyu Wang Lingling Yang Human sirtuin 2 (SIRT2), a member of the sirtuin family, has been considered as a promising drug target in cancer, neurodegenerative diseases, type II diabetes, and...
Fri Jul 26, 2019 03:00
Molecules, Vol. 24, Pages 2723: Synthesis of Flavone Derivatives via N-Amination and Evaluation of Their Anticancer Activities Molecules doi: 10.3390/molecules24152723 Authors: Ni Zhang Jin Yang Ke Li Jun Luo Su Yang Jun-Rong Song Chao Chen Wei-Dong Pan Seventeen new flavone derivatives substituted at the 4′-OH position were designed, synthesized and evaluated for their anticancer and antibacterial activities. Among them, compounds 3, 4, 6f, 6e, 6b, 6c...
Fri Jul 26, 2019 03:00
Molecules, Vol. 24, Pages 2721: Catalysis of Organic Pollutants Abatement Based on Pt-Decorated Ag@Cu2O Heterostructures Molecules doi: 10.3390/molecules24152721 Authors: Xiaolong Zhang Bingbing Han Yaxin Wang Yang Liu Lei Chen Yongjun Zhang Pt-decorated Ag@Cu2O heterostructures were successfully synthesized using a simple and convenient method. The Pt nanoparticle density on the Ag@Cu2O can be controlled by changing the concentration of the Pt precursor. The synthesized...
Fri Jul 26, 2019 03:00
Molecules, Vol. 24, Pages 2718: Optimizing Ultrasound-Assisted Deep Eutectic Solvent Extraction of Bioactive Compounds from Chinese Wild Rice Molecules doi: 10.3390/molecules24152718 Authors: Jia Zeng Yuqing Dou Ning Yan Na Li Huaibao Zhang Jia-Neng Tan In this study, deep eutectic solvents (DESs) were used for the ultrasound-assisted extraction (UAE) of valuable bioactive compounds from Chinese wild rice (Zizania spp.). To this end, 7 different choline chloride (CC)-based...
Fri Jul 26, 2019 03:00
Molecules, Vol. 24, Pages 2720: The High Efficiency of Anionic Dye Removal Using Ce-Al13/Pillared Clay from Darbandikhan Natural Clay Molecules doi: 10.3390/molecules24152720 Authors: Bakhtyar K. Aziz Dler M. Salh Stephan Kaufhold Pieter Bertier Natural clay from Darbandikhan (DC) was evaluated in its natural form, after acid activation (ADC), and after pillaring (PILDC) as a potential adsorbent for the adsorption of methyl orange (MO) as a model anionic dye adsorbate. The effect...
Fri Jul 26, 2019 03:00
Molecules, Vol. 24, Pages 2722: A Derivate of Benzimidazole-Isoquinolinone Induces SKP2 Transcriptional Inhibition to Exert Anti-Tumor Activity in Glioblastoma Cells Molecules doi: 10.3390/molecules24152722 Authors: He-ying Chen Liu-jun He Shi-qiang Li Ya-jun Zhang Jiu-hong Huang Hong-xia Qin Juan-li Wang Qian-yin Li Dong-lin Yang We have previously shown that compound-7g inhibits colorectal cancer cell proliferation and survival by inducing cell cycle arrest...
Fri Jul 26, 2019 03:00
Molecules, Vol. 24, Pages 2719: Design, Synthesis and Biological Evaluation of 1-Phenyl-2-(phenylamino) Ethanone Derivatives as Novel MCR-1 Inhibitors Molecules doi: 10.3390/molecules24152719 Authors: Xiu-juan Lan Hai-tao Yan Feng Lin Shi Hou Chen-chen Li Guang-shu Wang Wei Sun Jun-hai Xiao Song Li Polymyxins are considered to be the last-line antibiotics that are used to treat infections caused by multidrug-resistant (MDR) gram-negative bacteria; however, the...
Fri Jul 26, 2019 03:00
Molecules, Vol. 24, Pages 2716: Applicability Domain of Active Learning in Chemical Probe Identification: Convergence in Learning from Non-Specific Compounds and Decision Rule Clarification Molecules doi: 10.3390/molecules24152716 Authors: Ahsan Habib Polash Takumi Nakano Shunichi Takeda J.B. Brown Efficient identification of chemical probes for the manipulation and understanding of biological systems demands specificity for target proteins. Computational means to optimize candidate...
Fri Jul 26, 2019 03:00
Molecules, Vol. 24, Pages 2715: Enhanced Nanoencapsulation of Sepiapterin within PEG-PCL Nanoparticles by Complexation with Triacetyl-Beta Cyclodextrin Molecules doi: 10.3390/molecules24152715 Authors: Nataliya Kuplennik Alejandro Sosnik In this work, we aimed to improve the encapsulation efficiency of sepiapterin (SP), the natural precursor of the essential cofactor tetrahydrobiopterin (BH4) that displays mild water-solubility and a short biological half-life, within methoxy-poly(ethylene-glycol)-poly(epsilon-caprolactone)(mPEG-PCL)...
Fri Jul 26, 2019 03:00
Molecules, Vol. 24, Pages 2717: Facile Synthesis of 3-(Azol-1-yl)-1-adamantanecarboxylic Acids—New Bifunctional Angle-Shaped Building Blocks for Coordination Polymers Molecules doi: 10.3390/molecules24152717 Authors: Dmitry Pavlov Taisiya Sukhikh Evgeny Filatov Andrei Potapov For the first time, orthogonally substituted azole-carboxylate adamantane ligands were synthesized and used for preparation of coordination polymers. The angle-shaped ligands were prepared by the reaction...
Fri Jul 26, 2019 03:00
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