Single-Dose Neoadjuvant AKT Pathway Inhibitor Reduces Growth of Hepatocellular Carcinoma after Laser Thermal Ablation in Small-Animal Model   Single-dose neoadjuvant inhibition of phosphoinositide 3-kinase, mammalian target of rapamycin, and protein kinase B signaling in combination with thermal ablation may represent a candidate therapeutic strategy to prevent local recurrence of hepatocellular carcinoma after ablation.      Danielle E. Jondal, Scott M. Thompson...David A. Woodrum

Editorial: Treatment of Hepatocellular Carcinoma:Time for a Paradigm Shift? Sarah B. White