Klinefelter syndrome and germ cell tumors: review of the literature. Int J Pediatr Endocrinol. 2020;2020:18 Authors: Bonouvrie K, van der Werff Ten Bosch J, van den Akker M Abstract Objective: The most common presentation of Klinefelter syndrome (KS) is infertility and features of hypogonadism. Currently no consensus exists on the risk of malignancy in this syndrome. Several case reports show an incidence of extragonadal germ cells tumors (eGCT)...
Clinical characteristics and outcome of primary hepatic neuroendocrine tumors after comprehensive therapy. World J Gastrointest Oncol. 2020 Sep 15;12(9):1031-1043 Authors: Wang HH, Liu ZC, Zhang G, Li LH, Li L, Meng QB, Wang PJ, Shen DQ, Dang XW Abstract BACKGROUND: Primary hepatic neuroendocrine tumors (PHNETs), a group of neuroendocrine neoplasms, are extremely rare. There are only few case reports about PHNETs in the literature. The lack...
Yttrium-90 selective internal radiotherapy as bridge to curative hepatectomy for recurrent malignant solid pseudopapillary neoplasm of pancreas: case report and review of literature. J Surg Case Rep. 2020 Sep;2020(9):rjaa325 Authors: Dyas AR, Johnson DT, Rubin E, Schulick RD, Kumar Sharma P Abstract Recurrent malignant solid pseudopapillary neoplasms of the pancreas (SPNP) are rare tumors with unpredictable clinical and histopathological features....
Emergency surgery for gastrointestinal cancer: A nationwide study in Japan based on the National Clinical Database. Ann Gastroenterol Surg. 2020 Sep;4(5):549-561 Authors: Hoshino N, Endo H, Hida K, Ichihara N, Takahashi Y, Hasegawa H, Kimura T, Kitagawa Y, Kakeji Y, Miyata H, Nakayama T, Sakai Y Abstract Background: Emergency gastrointestinal surgery, although rare, is known for its high mortality and morbidity. However, the risks of emergency...
Simultaneous triple cancer of the esophagus, pancreas and rectum treated with multimodal strategies: a case report. Surg Case Rep. 2020 Oct 02;6(1):259 Authors: Imamura H, Hirose H, Endo S, Hashimoto Y, Takeda M, Kidogami S, Mokutani Y, Kishimoto T, Yoshioka S, Tamura S, Sasaki Y Abstract BACKGROUND: Due to the development of diagnostic imaging technology, we have increased chance of detecting multiple primary cancers. However, simultaneous...
Comprehensive genomic profiling for patients with chemotherapy-naïve advanced cancer. Cancer Sci. 2020 Oct 02;: Authors: Kondo T, Matsubara J, Pham Nguyen Q, Fukuyama K, Nomura M, Funakoshi T, Doi K, Sakamori Y, Yoshioka M, Yokoyama A, Tamaoki M, Kou T, Hirohashi K, Yamada A, Yamamoto Y, Minamiguchi S, Nishigaki M, Yamada T, Kanai M, Matsumoto S, Muto M Abstract Comprehensive genomic profiling (CGP) testing by next-generation sequencing has...
Publication date: Available online 2 October 2020Source: Human PathologyAuthor(s): Snjezana Dogan, Denise Frosina, Jerica A. Geronimo, Enmily Hernandez, Abhinita Mohanty, Tejus Bale, Jaclyn F. Hechtman, Maria E. Arcila, Meera R. Hameed, Achim A. Jungbluth
'COVID-19 Lockdown: A protective measure or exacerbator of health inequalities? A comparison between the United Kingdom and India.' A commentary on "The socio-economic implications of the coronavirus and COVID-19 pandemic: A review". Int J Surg. 2020 Sep 29;: Authors: Sardar S, Abdul-Khaliq I, Ingar A, Amaidia H, Mansour N PMID: 33007438 [PubMed - as supplied by publisher]
1O_LITraditionally, we expect that self-incompatibility alleles (S-alleles), which prevent self-fertilization, should benefit from negative-frequency dependent selection and rise to high frequency when introduced to a new population through gene flow. However, the most taxonomically widespread form of self-incompatibility, the ribonuclease-based system ancestral to the core eudicots, functions through nonself-recognition, which drastically alters the process of S-allele diversification. C_LIO_LIWe...
Abstract Objectives This study evaluated demographic patterns related to prenatal cannabinoid urine drug screening (UDS) over a 5-year period during which recreational marijuana was legalized and became accessible in Washington State. Methods Using electronic health record data, we performed a retrospective analysis for deliveries occurring over a...
27 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/10/03PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Odor perception depends on airflow, odor solubility and intranasal application site. Rhinology. 2020 Oct 02;: Authors: Chen B, Pfister A, Nahrath P, Hummel T Abstract To the Editor: Odorants are sensed by olfactory receptor neurons in the olfac- tory epithelium. Odor molecules pass through the nasal cavity and dissolve in the mucus of the olfactory epithelium which is located on the superior portion of the cavity. There they bind to olfactory...
The Olfactory Cleft Endoscopy Scale: a multi-institutional validation study in chronic rhinosinusitis. Rhinology. 2020 Oct 02;: Authors: Schlosser RJ, Smith TL, Mace JC, Alt JA, Beswick DM, Mattos JL, Ramakrishnan V, Massey C, Soler ZM Abstract BACKGROUND: Olfactory dysfunction (OD) associated with chronic rhinosinusitis (CRS) remains quite challenging. Instruments to precisely assess olfactory cleft anatomy and their association with olfaction...
Locally advanced nasal pyramid squamous cell carcinoma: our 15 years' experience in a series of 35 total rhinectomies. Rhinology. 2020 Oct 02;: Authors: Bouaoud J, Benmoussa N, Hennocq Q, Hennocq JF, Breuskin I, Gorphe P, Casiraghi O, Classe M, Blanchard P, Janot F, Kolb F, Leymarie N, Temam S, Moya-Plana A Abstract Locally advanced nasal pyramid squamous cell carcinoma (LA-NPSCC) are rare malignancies. Their specific outcomes are unclear....
The development of apalutamide for the treatment of prostate cancer. Expert Opin Drug Discov. 2020 Oct 02;: Authors: Isaacsson Velho P, Tofani Sant' Anna P, Pereira da Silva RF, Dal Ponte Ferreira R, Venero FC Abstract INTRODUCTION: Prostate cancer invariably progresses, despite androgen deprivation therapy, the backbone of its treatment. This progression is mainly related to androgen receptor (AR)-related mechanisms of resistance, and, several...
Recent Advances in Drug Discovery for Diabetic Kidney Disease. Expert Opin Drug Discov. 2020 Oct 01;: Authors: Danta CC, Boa AN, Bhandari S, Sathyapalan T, Xu SZ Abstract INTRODUCTION: Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease (ESRD), and 40% of patients with diabetes develop DKD. Although some pathophysiological mechanisms and drug targets of DKD have been described, the effectiveness or clinical usefulness...
Targeting the GLI Family of Transcription Factors for the Development of Anti-Cancer Drugs. Expert Opin Drug Discov. 2020 Oct 02;: Authors: Dusek C, Hadden MK Abstract INTRODUCTION: GLI1 is a transcription factor that has been identified as a downstream effector for multiple tumorigenic signaling pathways. These include the Hedgehog, RAS-RAF-MEK-ERK, and PI3K-AKT-mTOR pathways, which have all been separately validated as individual anti-cancer...
Approaches to Mitigate the Risk of Serious Adverse Reactions in Covalent Drug Design. Expert Opin Drug Discov. 2020 Oct 02;: Authors: Baillie TA Abstract INTRODUCTION: Covalent inhibition of target proteins using high affinity ligands bearing weakly electrophilic warheads is being adopted increasingly as design strategy in the discovery of novel therapeutics, and several covalent drugs have now received regulatory approval for indications in...
PET/CT in thyroid cancer - the importance of BRAF mutations. Nucl Med Rev Cent East Eur. 2020;23(2):97-102 Authors: Cuccurullo V, Di Stasio GD, Cascini GL Abstract Thyroid cancer (TC) represents less than 1% of all newly diagnosed malignancies. In some selected cases, with a high clinical suspicion for disease but negative I-131 scan, positron emission tomography/computed tomography (PET) with F-18-Fluorodeoxyglucose (FDG) could be helpful...
Related Articles Unusual Mimicker of the Carotid Body Tumor: Synovial Sarcoma of the Carotid Space. J Craniofac Surg. 2020 Jun;31(4):e397-e398 Authors: Gozgec E, Ogul H Abstract Synovial cell sarcomas are malignant tumors originating from pluripotent mesenchymal stem cells, unlike its name. It is a common tumor in the periarticular area, accounting for 8% of all soft tissue sarcomas. Head and neck are among the rarest areas of this tumor. Synovial...
Perinatal atypical teratoid/rhabdoid tumor involving the deep ear structures and complicated by arterial infarction. Radiol Case Rep. 2020 Nov;15(11):2433-2439 Authors: Alharbi OA, Almushayqih MH, Alqahtani A, Alsuhaibani MS Abstract Atypical teratoid/rhabdoid tumor is a malignant pediatric brain tumor. Unusual invasive behavior of the dura and bony involvement of the deep ear structures and rapid progression in size complicated by arterial...
Migration of Broken Dental Needle Through the Internal Jugular Vein in the Parapharyngeal Space. Mil Med. 2020 Oct 02;: Authors: Teixeira JC, Adidharma L, Coppit GL, Cardoni W Abstract Accidental broken dental needles during dental blocks have become a rare occurrence but still occur. Although the treatment for such occurrence is controversial, an increasing body of literature demonstrates that migration of such needles is possible. In this...
Striae gravidarum and different modalities of therapy: a review and update. J Dermatolog Treat. 2020 Oct 02;:1-9 Authors: Yu Y, Wu H, Yin H, Lu Q Abstract The term striae gravidarum (SG) refers to a kind of striae distensae (SD) that develops particularly during pregnancy. According to the level of maturity of the lesions, SG is divided into striae rubra (SR) and striae alba (SA). The pathogenesis remains unclear; recent studies have implicated...
Acoustic shock: an update review. J Laryngol Otol. 2020 Oct 02;:1-6 Authors: Parker WAE, Parker VL, Parker G, Parker AJ Abstract BACKGROUND: This paper discusses the concept of acoustic shock based on a literature review and the results of our own research into cases seen in both clinical and medicolegal practice. With the demise of traditional 'metal bashing' and 'smoke stack' heavy industries, there has been a decline in the incidence of...
Publication date: Available online 2 October 2020Source: Annals of Anatomy - Anatomischer AnzeigerAuthor(s): Esther Mingorance, Raquel Mayordomo, Ana María Pérez-Pico, Francisco Tirado, Yolanda Macías, Yolanda Gañán
Atopic dermatitis (AD) is associated with chronic skin inflammation of barrier disruption. Affected patients have high rates of allergic sensitization and skin colonization with Staphylococcus aureus. This study sought to identify AD endotypes based on allergen sensitization, S. aureus reactivity, and inflammatory signature. The study included 76 adults with moderate to severe AD and 39 healthy controls. All underwent serologic assessment of total IgE and allergen-specific antibodies to a wide range...
Abstract Objectives To investigate differential item functioning across the Spanish and English versions of the Orofacial Esthetic Scale (OES). Methods OES data were collected from a consecutive sample of a total of 622 adult dental patients (311 English‐ and 311 Spanish‐speaking adults) from HealthPartners dental clinics in Minnesota. We inspected boundary characteristic curves (BCCs) based on item response theory (IRT) in English and Spanish‐speakers to examine differential item functioning...
Publication date: Available online 2 October 2020Source: Seminars in Ultrasound, CT and MRIAuthor(s): Antonio Pinto
[PARP inhibitors in breast cancer: Current clinical development and perspectives]. Bull Cancer. 2020 Sep 28;: Authors: Robbe J, Moretta J, Vicier C, Sabatier R, Noguès C, Gonçalves A Abstract The association of a germline mutation in the BRCA1/2 genes in breast cancer leads to a higher genomic instability and, thus, a potential higher sensitivity to poly(ADP-ribose) polymerase (PARP) inhibitors. In this review, we will summarize the different...
Publication date: Available online 2 October 2020Source: Radiotherapy and OncologyAuthor(s): Ernst S. Kooreman, Petra J. van Houdt, Rick Keesman, Floris J. Pos, Vivian W.J. van Pelt, Marlies E. Nowee, Andreas Wetscherek, Rob H.N. Tijssen, Marielle E.P. Philippens, Daniela Thorwarth, Jihong Wang, Amita Shukla-Dave, William A. Hall, Eric S. Paulson, Uulke A. van der Heide
Purpose: To report local disease control and all-cause mortality in patients with extraocular extension (EOE) of uveal melanoma undergoing enucleation followed by observation or external beam radiotherapy (EBRT). Methods: Charts of patients enucleated between January 1, 1997 and December 31, 2019, with histopathological evidence of EOE of uveal melanoma were reviewed. Results: The cohort comprised 51 patients with a mean age of 67 ± 15 years, 22 (43%) of whom underwent adjuvant postenucleation...
Purpose: To report the etiology, management, and possible risk factors for diplopia after canalicular bypass surgery. Methods: A multicenter retrospective, noncomparative case series of patients who developed diplopia following canalicular bypass surgery were assessed. Results: Twenty-four cases of diplopia were identified across 12 institutions. Tubes were inserted as a primary procedure with external dacryocystorhinostomy (DCR) (1; 4%) or without DCR (10; 42%) or as a secondary procedure...
Purpose: To compare the accuracy and positive predictive values of the air bubble test (ABT) and endoscopic Jones I test for assessment of anatomical and functional success after diode laser transcanalicular dacryocystorhinostomy (T-DCR). Methods: This cross-sectional study included 60 eyes of 56 patients who underwent T-DCR by a single surgical team from January 2016 to December 2018. All the 56 patients (60 eyes) underwent lacrimal syringing, endoscopic Jones I test, and ABT. Anatomical...
Purpose: Information regarding risk of metastasis and disease-related death (DD) from conjunctival squamous cell carcinoma (SCC) is relatively scarce. We explored prognostic factors for orbital exenteration, local recurrence, nodal metastasis, and DD in patients with conjunctival SCC. Design: Retrospective cross-sectional study. Methods: All consecutive patients with conjunctival SCC treated by the senior author at MD Anderson Cancer Center during1999–2018 were included. Survival curves...
Oncocytoma is a rare benign neoplasm with few cases reported to involve the orbit. When affecting the orbit, oncocytomas have very slow growth and often evade early diagnosis. The diagnostic evaluation of these orbital tumors is not fully understood. The authors present a case of a benign oncocytoma arising in the lacrimal gland associated with significant vascularity and intraoperative bleeding. The authors provide immunohistochemical analysis of this rare orbital tumor and insights in surgical...
HER2-positive breast cancer that resists therapeutic drugs and ionizing radiation releases sphingomyelin-based molecules to circulating blood serum. Mol Clin Oncol. 2020 Dec;13(6):70 Authors: Monzen S, Tatara Y, Mariya Y, Chiba M, Wojcik A, Lundholm L Abstract Breast cancer is the second most common cancer in the world based on incidence, reaching more than 2 million new cases in 2018, while continuing to increase. Invasive ductal carcinoma...
Related Articles Increased calcium channel in the lamina propria of aging rat. Aging (Albany NY). 2019 10 31;11(20):8810-8824 Authors: Kim JM, Heo HS, Shin SC, Kwon HK, Lee JC, Sung ES, Kim HS, Park GC, Lee BJ Abstract The alterations of the extracellular matrix (ECM) in lamina propria of the vocal folds are important changes that are associated with decreased vibrations and increased stiffness in aging vocal fold. The aim of this study was...
Related Articles Role of TFF3 as an adjunct in the diagnosis of Barrett's esophagus using a minimally invasive esophageal sampling device-The CytospongeTM. Diagn Cytopathol. 2020 Mar;48(3):253-264 Authors: Paterson AL, Gehrung M, Fitzgerald RC, O'Donovan M Abstract The incidence of esophageal carcinoma continues to increase whilst its prognosis remains poor. The most dramatic reduction in mortality is likely to follow early diagnosis of the...
Related Articles Effect of seasonal variance on intestinal epithelial barriers and the associated innate immune response of the small intestine of the Chinese soft-shelled turtles. Fish Shellfish Immunol. 2020 Feb;97:173-181 Authors: Shi Y, Vistro WA, Bai X, Wu R, Chen C, Huang Y, Fazlani SA, Tarique I, Yang P, Chen Q Abstract It is conceivable that pathological conditions can cause intestinal barrier disruption and innate immune dysfunction....
Authors' reply to: Comment on the article by Dr. S. Yetiser: A new variant of posterior canal-benign paroxysmal positional vertigo-canalolithiasis. Auris Nasus Larynx. 2020 Sep 28;: Authors: Shigeno K PMID: 33004254 [PubMed - as supplied by publisher]
Transoral Laser Microsurgery (TLM) for Glottic Cancer: Prospective Assessment of a New Pathology Workup Protocol. Front Surg. 2020;7:56 Authors: Meulemans J, Hauben E, Peeperkorn S, Nuyts S, Delaere P, Vander Poorten V Abstract Background/Purpose: The value of margin status after TLM for glottic cancer is debatable, due to difficulties in specimen orientation and margin analysis. Purpose of this study was the prospective evaluation of feasibility...
A Rare Cause of Extremely Loud Expiratory Stridor in a 11-Year-Old Patient. Laryngoscope. 2020 Oct 02;: Authors: Cantarella G, Ciabatta AC Abstract Stridor can be a very alarming symptom in children, as it is typically caused by turbulent airflow through a partially obstructed airway, due to an organic cause. An abnormal respiratory sound can induce the suspicion of a life-threatening clinical condition and requires an immediate diagnostic...
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Phoebe C.I. Ng, Judy Y.W. Chan, Ross K.K. Leung, J. Li, Z. Ren, Anthony W.H. Chan, Y. Xu, S.S. Lee, R. Wang, Xia Ji, Jun Zheng, Denise P.C. Chan, W.W. Yew, Simon M.Y. Lee
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Mei Guo, Chengzhong You, Wenqi Dong, Biao Luo, Yuheng Wu, Yanuo Chen, Jianping Li, Meng Pan, Miao Li, Fengshu Zhao, Jun Dou
Surgical treatment of double parathyroid adenomas in primary hyperparathyroidism: A clinical case. Int J Surg Case Rep. 2020 Sep 03;: Authors: Ilyicheva EA, Bersenev GA Abstract INTRODUCTION: The frequency of occurrence of double parathyroid adenomas in patients with primary hyperparathyroidism is from 2 to 11% of cases. Nowadays, double adenomas remain a difficult diagnostic and therapeutic task. PRESENTATION OF CASE: A 64-year-old...
Primary spindle cell sarcoma of the heart treated with carbon-ion radiotherapy: Case report. Int J Surg Case Rep. 2020 Sep 25;76:1-4 Authors: Shibasaki I, Toyoda S, Takei Y, Chida M, Fukuda H Abstract INTRODUCTION: Primary cardiac sarcoma is a rare malignant cardiac neoplasm with a poor prognosis. No evidence-based guidelines exist regarding surgical treatment management, although some case reports have been published. We report the outcome...
Dynamic CTA-Derived Perfusion Maps Predict Final Infarct Volume: The Simple Perfusion Reconstruction Algorithm. AJNR Am J Neuroradiol. 2020 Oct 01;: Authors: McDougall CC, Chan L, Sachan S, Guo J, Sah RG, Menon BK, Demchuk AM, Hill MD, Forkert ND, d'Esterre CD, Barber PA Abstract BACKGROUND AND PURPOSE: Infarct core volume measurement using CTP (CT perfusion) is a mainstay paradigm for stroke treatment decision-making. Yet, there are several...
Abstract Objective To identify the prevalence of alcohol and tobacco drug use among pregnant women and investigate their perceptions regarding advice from health professionals during prenatal care. Method We used a sequential explanatory mixed-methods design for this cross-sectional study; the study period was January 2017 to December 2018. Multistage...
Vitamin A is involved in maintenance of gut mucosal integrity and normal immune function. However, it is unclear whether these functions of vitamin A have any beneficial effects in patients undergoing hematopo...
To describe the calcium concentration of tap and bottled waters from Argentina and to estimate the contribution of drinking water to calcium recommendations.
Colorectal cancer (CRC) is the third most common cancer across the world that multiple risk factors together contribute to CRC development. There is a limited research report on impact of nutritional risk fact...
MicroRNA-204-5p mediates sevoflurane-induced cytotoxicity in HT22 cells by targeting brain-derived neurotrophic factor. Histol Histopathol. 2020 Oct 02;:18266 Authors: Liu H, Wang J, Yan R, Jin S, Wan Z, Cheng J, Li N, Chen L, Yue C Abstract BACKGROUND: Sevoflurane is widely used as an inhalational anesthetic in clinical practice. However, sevoflurane can cause cytotoxicity and induce learning capacity decline in patients. A previous publication...
Once in the Door, Grit May Matter More: An Evaluation of Grit in Medical Students. Mil Med. 2020 Oct 02;: Authors: Ursua F, Altholz J, Durning S, Torre D, Dong T Abstract INTRODUCTION: Health professions educators seek understanding of the process of learner performance and achievement. Grit, defined as passion and perseverance for long-term goals, has been implicated in this process. Research suggests that effort counts twice in achievement:...
Triage Decisions in the Context of COVID-19: Old Burden, New Challenge-The Structured Approach for Intensive Care Unit Triage (SAINT) Protocol. Mil Med. 2020 Oct 02;: Authors: Jänig C, Forklage R, Gurney JM, Groth R, Wirth C, van de Krol H, Schmidbauer W, Güsgen C Abstract INTRODUCTION: The medical treatment facilities (MTF) represent the equivalent of the healthcare system in the home countries, but they face the limitations of an outpost...
A Response to "A Comparison of Improvised and Commercially Available Point-of-Wounding Tourniquets in Simulated Traumatic Amputation with Catastrophic Hemorrhage". Mil Med. 2020 Oct 02;: Authors: Carius BM, Dodge PM, Fisher AD PMID: 33005929 [PubMed - as supplied by publisher]
Health Behaviors Among Service Members Injured on Deployment: A Study From the Wounded Warrior Recovery Project. Mil Med. 2020 Oct 02;: Authors: McCabe CT, Watrous JR, Galarneau MR Abstract INTRODUCTION: Service members (SMs) who are injured on deployment are at risk for myriad long-term health problems that may be ancillary to their physical injury, including high rates of depression and posttraumatic stress disorder, and poor health behaviors...
Toward a "Dashboard" Indicator of Retention in U.S. Navy Personnel. Mil Med. 2020 Oct 02;: Authors: Taylor MK, Hernández LM, Clinton-Sherrod AM Abstract INTRODUCTION: Retention is a top priority for the U.S. Navy. However, our understanding of factors influencing retention of Navy personnel is limited. Current research implies that poor mental health, low appraisals of unit cohesion, low leadership satisfaction, and low social support may adversely...
E-Cigarette Use and Perceptions Among Veterans Receiving Outpatient Treatment in Veterans Affairs Substance Use and Mental Health Clinics. Mil Med. 2020 Oct 02;: Authors: Dixit D, Herbst E, Das S Abstract INTRODUCTION: Individuals with substance use disorders and/or mental health (MH) conditions have higher rates of cigarette smoking than the general population. Electronic nicotine delivery systems (ENDS) while gaining popularity pose health...
Obstacles to an Effective Low-Titer O Walking Blood Bank: A Deployed Unit's Experience. Mil Med. 2020 Oct 02;: Authors: Gaspary MJ, Kyle AI, Lawson SM, Birkla J, Bolton ED, Bergeron KP, Tiller MM Abstract INTRODUCTION: We present the experience of our U.S. Navy Role 2's deployment to the U.S. Central Command area of responsibility in support of Operation Inherent Resolve and serving a multinational, joint-service military base. We detail our...
"Road Rash" and Dizziness: A Case of Hemodynamically Significant Topical Clonidine Toxicity. Mil Med. 2020 Oct 02;: Authors: Downs JW, Cumpston KL Abstract Clonidine is a central alpha-2 agonist well known to produce a syndrome of bradycardia and hypotension in overdose. However, few examples of overt clinical clonidine toxicity secondary to cutaneous absorption have been reported. We report a case of unintentional systemic clonidine toxicity...
Red Cell Distribution Width, Unlike Neutrophil Lymphocyte Ratio Is Unable to Accurately Gauge Enhanced Systemic Inflammation Associated With Panoramic Imaged Carotid Plaque. Mil Med. 2020 Oct 02;: Authors: Chang TI, Wu X, Boström KI, Tran HA, Friedlander AH Abstract INTRODUCTION: We have previously shown that panoramic X-rays (PXs) demonstrating calcified carotid artery atheromas (CCAA) are associated with increased systemic inflammation demonstrating...
Post-awakening Cortisol in Explosive Ordnance Disposal Technicians: A Replication Study in a Novel Population. Mil Med. 2020 Oct 02;: Authors: Hernández LM, Padilla GA, Koehn BW, Taylor MK Abstract INTRODUCTION: Amassing evidence suggests that post-awakening salivary cortisol rhythms (changes in cortisol throughout the day) may indicate health status. We previously established summary parameters for salivary cortisol in U.S. Navy Sea, Air,...
Migration of Broken Dental Needle Through the Internal Jugular Vein in the Parapharyngeal Space. Mil Med. 2020 Oct 02;: Authors: Teixeira JC, Adidharma L, Coppit GL, Cardoni W Abstract Accidental broken dental needles during dental blocks have become a rare occurrence but still occur. Although the treatment for such occurrence is controversial, an increasing body of literature demonstrates that migration of such needles is possible. In this...
Feasibility of a Clinical Decision Support Tool to Manage Resistant Hypertension: Team-HTN, a Single-arm Pilot Study. Mil Med. 2020 Oct 03;: Authors: Siaki LA, Lin V, Marshall R, Highley R Abstract INTRODUCTION: Based on defining criteria, hypertension (HTN) affects 31% to 46% of the adult U.S. population and almost 20% of service members. Resistant HTN (rHTN) consumes significant resources, carries substantial morbidity and mortality risk...
The Impact of a Virtual Radiology Medical Student Rotation: Maintaining Engagement During COVID-19 Mitigation. Mil Med. 2020 Oct 03;: Authors: Adams CC, Shih R, Peterson PG, Lee MH, Heltzel DA, Lattin GE Abstract INTRODUCTION: The purpose of this study is to introduce a virtual radiology rotation curriculum that is being used to safely maintain medical student and intern education and engagement with the Department of Radiology at Walter Reed...
Creation and Operation of a Task Force Hospital by Armed Forces in the Epicenter of Coronavirus Disease 2019. Mil Med. 2020 Oct 03;: Authors: Go S, Jeong CY, Shin BS, Ahn J, Oh IM, Park C, Kim K, Seo JW, Oh HS PMID: 33007061 [PubMed - as supplied by publisher]
Corrigendum to: Augmented Reality Forward Damage Control Procedures for Non-Surgeons: A Feasibility Demonstration. Mil Med. 2020 Oct 03;: Authors: PMID: 33007062 [PubMed - as supplied by publisher]
E-Cigarette or Vaping Product Use-Associated Lung Injury (EVALI) in an Active Duty Service Member. Mil Med. 2020 Oct 03;: Authors: Colesar MT, McCollum DJ Abstract E-cigarette or vaping product use-associated lung injury (EVALI) is a developing serious pulmonary disease associated with the increasing use of vaping products in both civilian and active duty populations. This case study describes an active duty trainee using unbranded vaping products...
Oral Health Status Among Adults With and Without Prior Active Duty Service in the U.S. Armed Forces, NHANES 2011-2014. Mil Med. 2020 Oct 03;: Authors: Schindler DK, Lopez Mitnik GV, Soliván-Ortiz AM, Irwin SP, Boroumand S, Dye BA Abstract INTRODUCTION: Many veterans qualify for health benefits but generally not dental care. This study examines differences in oral health status between veterans and nonveterans in the U.S. to determine how various...
An Assessment of Pre-deployment Training for Army Nurses and Medics. Mil Med. 2020 Oct 03;: Authors: Suresh MR, Valdez-Delgado KK, Staudt AM, Trevino JD, Mann-Salinas EA, VanFosson CA Abstract INTRODUCTION: Although military nurses and medics have important roles in caring for combat casualties, no standardized pre-deployment training curriculum exists for those in the Army. A large-scale, survey-based evaluation of pre-deployment training...
Post-mTBI Pain Interference in a U.S. Military Population: A Chronic Effects of Neurotrauma Consortium Study. Mil Med. 2020 Oct 03;: Authors: Khokhar BR, Lindberg MA, Walker WC Abstract INTRODUCTION: Chronic pain is a significant problem for service members and veterans with mild traumatic brain injury (mTBI). While the root cause of pain is not clearly understood, comorbidities may contribute to how their pain disrupts their functional status,...
The Medical Relief in Place for United States Forces: Considerations, Risks, and Interoperability. Mil Med. 2020 Oct 03;: Authors: Curtin JM, Marle A, Lock C, McLeroy RD, Martinez LJ, Wilson RL PMID: 33007068 [PubMed - as supplied by publisher]
A Survey of Energy Drink Consumption and Associated Adverse Effects in Air Force Personnel. Mil Med. 2020 Oct 03;: Authors: Milazzo NA, Cao DX, Diwaker G, Thornton JA, Shah SA Abstract INTRODUCTION: Energy drinks are an increasingly utilized beverage and are gaining popularity in recent years. The U.S. Air Force (USAF) represents a unique population where energy drink consumption may be higher than the general population. To better understand...
Incidental Finding of Tuberculosis During Evaluation for Delayed Wound Healing. Mil Med. 2020 Oct 03;: Authors: Kunciw SE, de la Cruz EC Abstract Cutaneous tuberculosis (TB) is an uncommon form of extrapulmonary TB that can be difficult to diagnose. The following case is about a 14-year-old female who was experiencing delayed wound healing after an incision and drainage of a chest wall abscess. A computed tomography scan of her chest obtained...
Prolonged Field Care Research Approach and Its Relevance to Civilian Medicine. Mil Med. 2020 Oct 03;: Authors: Cohen AB, Davis M, Herman SEM Abstract In early March 2020, Johns Hopkins University Applied Physics Lab hosted an Association of Military Surgeons of the United States regional conference to address medical demands of the future battlefield for which prolonged field care is expected. Arising from this conference, we propose here an...
Penetrating Neck Injuries Treated at a U.S. Role 3 Medical Treatment Facility in Afghanistan During Operation Resolute Support. Mil Med. 2020 Oct 03;: Authors: Breeze J, Gensheimer WG, DuBose JJ Abstract INTRODUCTION: Military trauma registries can identify broad epidemiological trends from neck wounds but cannot reliably demonstrate temporal casualty from clinical interventions or differentiate penetrating neck injuries (PNI) from those that...
Smoking and Physical Activity Patterns of U.S. Military Veterans With Chronic Obstructive Pulmonary Disease: An Analysis of 2017 Behavioral Risk Factor Surveillance System. Mil Med. 2020 Oct 03;: Authors: Greiner B, Ottwell R, Corcoran A, Hartwell M Abstract INTRODUCTION: The prevalence of chronic obstructive pulmonary disease (COPD) in U.S. military veterans is higher than that of non-veterans. Smoking and physical activity behaviors of veterans...
Background: The optimal age for cleft palate repair continues to be debated, with little discussion of surgical risk related to operative timing. This study of 3088 cleft palate patients analyzed the impact of surgical timing on perioperative and 30-day post-operative outcomes. Methods: Primary cleft palate repairs were identified in the National Surgical Quality Improvement (NSQIP) database from 2012-2015. Data were combed for total post-operative complications, rates of readmission...
Background: Clinical characteristics and timing associated with nonsurgical recovery of upper extremity function in acute flaccid myelitis (AFM) are unknown. Methods: A single institution retrospective case series was analyzed to describe clinical features of AFM diagnosed between October 2013 and December 2016. Patients were consecutively sampled children with a diagnosis of AFM who were referred to a hand surgeon. Patient factors and initial severity of paralysis were compared with...
Objective: To describe our patient selection, surgical technique, and results with the alar rotation flap for surgical defects of the nasal ala. Materials and Methods: We performed a retrospective analysis of all alar rotation flaps performed between June 2006 and February 2019. Three hundred ninety-four patients were identified and follow-up encounters were reviewed to assess for complications and need for revisionary procedures. Results: The alar rotation flap was performed...
BACKGROUND: Post-mastectomy breast reconstruction techniques differentially influence patient-reported physical and psychosocial well-being. Objective measures of shoulder biomechanics, which are uniquely influenced by reconstruction technique, may provide insight into the influence of reconstruction technique on patient-reported outcomes. METHODS: Robot-assisted measures of shoulder strength and stiffness, and patient-reported outcomes surveys (PROMIS-UE, SPADI, QuickDASH, SF12-PCS,...
No abstract available
Plastic and Reconstructive Surgery (PRS) has an illustrious history of innovation. The advancement, if not the survival of the specialty, depends on the continual development and improvement of procedures, practices, and technologies. It follows that the safe adoption of innovation into clinical practice is also paramount. Traditionally, adoption has relied on the diffusion of new knowledge, which is a consistent, but slow and passive process. The emerging field of dissemination and implementation...
Introduction: Traditionally, lymphovenous anastomosis (LVA) is not routinely performed in the patients with advanced stage lymphedema due to difficulty with identifying functioning lymphatics. This study presents the use of Duplex ultrasound and MR lymphangiogram to identify functional lymphatics and clinical outcome of LVA in advanced stage lower extremity lymphedema patients. Materials and Methods: This is a retrospective study of 42 patients (50 lower limbs) with advanced lymphedema...
Background: Cleft surgeons try to construct a philtral ridge during primary repair of a cleft lip, but rarely document the results. We used three-dimensional photogrammetry to measure projection of philtral ridges after closure of the common forms of unilateral labial cleft. Methods: This is a retrospective study of patients with unilateral complete, incomplete (moderate and severe), and microform cleft lip repaired by one surgeon from 2000 to 2013. Cleft type determined the technique...
Toxicological impact of sodium benzoate on inflammatory cytokines, oxidative stress and biochemical markers in male Wistar rats. Drug Chem Toxicol. 2020 Oct 01;:1-10 Authors: Khan IS, Dar KB, Ganie SA, Ali MN Abstract Sodium benzoate is a widely used food and pharmaceutical preservative due to its antibacterial and antifungal activity. In the present study effect of different concentrations of sodium benzoate on hepatic antioxidants, inflammatory...
Vocal Fold Collision Speed in vivo: The Effect of Loudness. J Voice. 2020 Sep 28;: Authors: DeJonckere PH, Lebacq J Abstract Mechanical impact stress on the vocal fold surface, particularly when excessive, has been postulated to cause the so-called phonotraumatic tissue lesions, such as nodules and polyps. The collision stress between the vocal folds depends on the vocal fold velocity at the time of impact. Hence this vocal fold collision speed...
Authors: Beatriz do Vale, Ana Patrícia Lopes, Maria da Conceição Fontes, Mário Silvestre, Luís Cardoso and Ana Cláudia Coelho.Parasite Vol. 27 , page 52Published online: 29/09/2020 Keywords: Companion animals ; Europe ; Systematic review ; Thelazia callipaeda ; Thelaziosis ; Wildlife.
291 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/10/03PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Publication date: Available online 3 October 2020Source: American Journal of Infection ControlAuthor(s): Shelly Miller, Debanjan Mukherjee, Joseph Wilson, Nicholas Clements, Cedric Steiner
Evidence around careers show that many surgeons are inspired early in their career, often based on their undergraduate experience. In this context we reviewed the location of the first degrees of Oral and Maxillofacial Surgery (OMFS) consultants and specialty trainees to look for any patterns or trends. It has been shown that there is variation across medical schools when core surgical trainee recruitment is analysed. No previous paper has undertaken a similar analysis of medical and dental schools...
Recent studies have indicated that the use of recombinant human bone morphogenetic protein-2 (rhBMP-2) is a viable adjunctive to alveolar cleft reconstruction owing to its osteoinductive capacity. This study aimed to evaluate the efficacy of rhBMP-2 in the treatment of alveolar cleft with autologous bone graft by precise volumetric analysis. Twenty-six patients (ages 8 to 14) with unilateral alveolar clefts were enrolled in this comparative study. Patients were divided into two groups: the iliac...
Abstract In this study, K. oxytoca KMS004 (ΔadhE Δpta-ackA) was further reengineered by the deletion of frdABCD and pflB genes to divert carbon flux through D-(−)-lactate production. During fermentation of high glucose concentration, the resulted strain named K. oxytoca KIS004 showed poor in growth and glucose consumption due to its insufficient capacity to generate acetyl-CoA for biosynthesis. Evolutionary adaptation was thus employed with the strain...
Publication date: Available online 2 October 2020Source: Academic RadiologyAuthor(s): JunziShi, Catherine S Giess, Tyler Martin, Karen A Lemaire, Patrick J Curley, Camden Bay, William W Mayo-Smith, Giles W Boland, Ramin Khorasani
Abstract Background Expanded myeloid-derived suppressor cells (MDSCs) correlate with disseminated metastases and poor prognosis in various human cancers. However, the role of MDSCs in gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) is still unknown. We investigated the distribution of MDSCs and their clinical significance in patients with GEP-NENs. Methods ...
Publication date: Available online 2 October 2020Source: Hearing ResearchAuthor(s): M.J. van Gendt, M. Siebrecht, J.J. Briaire, S.M. Bohte, J.H.M. Frijns
Publication date: Available online 2 October 2020Source: Hearing ResearchAuthor(s): Florian Langner, Colette M. McKay, Andreas Büchner, Waldo Nogueira
Abstract Objective Cytochrome b5-reductase (CYB5R) and cytochrome P450 reductase (CYPOR) are important for cell metabolism; however, their role in thyroid hormonogenesis and carcinogenesis has not been elucidated yet. The activity of CYB5R correlates with the metastasis in breast cancer, but there are no similar studies for CYB5R and CYPOR for thyroid tumors. The aim of this study was to elucidate the activity of CYB5R and CYPOR changes...
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