IJERPH, Vol. 16, Pages 2594: Risk, Transformation and Adaptation: Ideas for Reframing Approaches to Disaster Risk Reduction International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16142594 Authors: Douglas Paton Petra Buergelt Recognition of projected increases in exposure to large-scale hazard events over the coming decades has identified a need to develop how disaster risk reduction and recovery are conceptualized and enacted. This paper discusses some...
Sat Jul 20, 2019 03:00
Cancers, Vol. 11, Pages 1026: Spatiotemporal pH Heterogeneity as a Promoter of Cancer Progression and Therapeutic Resistance Cancers doi: 10.3390/cancers11071026 Authors: David E. Korenchan Robert R. Flavell Dysregulation of pH in solid tumors is a hallmark of cancer. In recent years, the role of altered pH heterogeneity in space, between benign and aggressive tissues, between individual cancer cells, and between subcellular compartments, has been steadily elucidated. Changes in temporal...
Sat Jul 20, 2019 03:00
Robotics, Vol. 8, Pages 59: Fault Diagnosis for UAV Blades Using Artificial Neural Network Robotics doi: 10.3390/robotics8030059 Authors: Gino Iannace Giuseppe Ciaburro Amelia Trematerra In recent years, unmanned aerial vehicles (UAVs) have been used in several fields including, for example, archaeology, cargo transport, conservation, healthcare, filmmaking, hobbies and recreational use. UAVs are aircraft characterized by the absence of a human pilot on board. The extensive use...
Sat Jul 20, 2019 03:00
Biomolecules, Vol. 9, Pages 293: Genome-Wide Identification and Expression Profiling of CBL-CIPK Gene Family in Pineapple (Ananas comosus) and the Role of AcCBL1 in Abiotic and Biotic Stress Response Biomolecules doi: 10.3390/biom9070293 Authors: Aslam Fakher Jakada Zhao Cao Cheng Qin Ca2+ serves as a ubiquitous second messenger regulating several aspects of plant growth and development. A group of unique calcium sensor proteins, calcineurin B-like (CBL), interact...
Sat Jul 20, 2019 03:00
Fermentation, Vol. 5, Pages 66: Mannoprotein Content and Volatile Molecule Profiles of Trebbiano Wines Obtained by Saccharomyces cerevisiae and Saccharomyces bayanus Strains Fermentation doi: 10.3390/fermentation5030066 Authors: Braschi Ricci Grazia Versari Patrignani Lanciotti : The production of volatile compounds has become one of the major technological features for yeast selection. In fact, although the aromatic profile of the wine is the sum of varietal-, pre-,...
Sat Jul 20, 2019 03:00
Metabolites, Vol. 9, Pages 148: Intracellular Staphylococcus aureus Elicits the Production of Host Very Long-Chain Saturated Fatty Acids with Antimicrobial Activity Metabolites doi: 10.3390/metabo9070148 Authors: Natalia Bravo-Santano James K. Ellis Yolanda Calle Hector C. Keun Volker Behrends Michal Letek As a facultative intracellular pathogen, Staphylococcus aureus is able to invade and proliferate within many types of mammalian cells. Intracellular bacterial replication...
Sat Jul 20, 2019 03:00
Water, Vol. 11, Pages 1507: Low-End Probabilistic Sea-Level Projections Water doi: 10.3390/w11071507 Authors: Gonéri Le Cozannet Rémi Thiéblemont Jeremy Rohmer Déborah Idier Jean-Charles Manceau Robin Quique In the area of sea-level rise, recent research has focused on assessing either likely or high end future sea levels, but less attention has been given to “low-end” sea-level projections, exploring best-case potential sea-level changes and providing...
Sat Jul 20, 2019 03:00
Water, Vol. 11, Pages 1506: Identifying a Suitable Model for Low-Flow Simulation in Watersheds of South-Central Chile: A Study Based on a Sensitivity Analysis Water doi: 10.3390/w11071506 Authors: Víctor Parra Jose Luis Arumí Enrique Muñoz Choosing a model that suitably represents the characteristics of a watershed to simulate low flows is crucial, especially in watersheds whose main source of baseflow generation depends on groundwater storage and release. The goal of this investigation...
Sat Jul 20, 2019 03:00
Viruses, Vol. 11, Pages 667: A Protocol for Extraction of Infective Viromes Suitable for Metagenomics Sequencing from Low Volume Fecal Samples Viruses doi: 10.3390/v11070667 Authors: Ling Deng Ronalds Silins Josué L. Castro-Mejía Witold Kot Leon Jessen Jonathan Thorsen Shiraz Shah Jakob Stokholm Hans Bisgaard Sylvain Moineau Dennis Sandris Nielsen The human gut microbiome (GM) plays an important role in human health and diseases. However, while substantial...
Sat Jul 20, 2019 03:00
Viruses, Vol. 11, Pages 668: Transport Via Macropinocytic Vesicles is Crucial for Productive Infection with Bombyx Mori Nucleopolyhedrovirus Viruses doi: 10.3390/v11070668 Authors: Jinshan Huang Chenya Li Xudong Tang Lin Liu Wenbin Nan Xingjia Shen Bifang Hao Bombyx mori nucleopolyhedrovirus (BmNPV) is a serious viral pathogen in the sericulture industry and enters host cells via macropinocytic endocytosis; however, the current understanding of the BmNPV entry mechanism...
Sat Jul 20, 2019 03:00
Molecules, Vol. 24, Pages 2641: Analysis of Proteins Associated with Quality Deterioration of Grouper Fillets Based on TMT Quantitative Proteomics during Refrigerated Storage Molecules doi: 10.3390/molecules24142641 Authors: Zhang Xie A TMT (Tandem Mass Tag)-based strategy was applied to elucidate proteins that change in proteomes of grouper fillets during refrigerated storage. In addition, quality analyses on pH, centrifugal loss, color (L *, a *, b *) and texture (hardness, chewiness,...
Sat Jul 20, 2019 03:00
Pharmacy, Vol. 7, Pages 99: Applying Contemporary Management Principles to Implementing and Evaluating Value-Added Pharmacist Services Pharmacy doi: 10.3390/pharmacy7030099 Authors: Shane P. Desselle Leticia R. Moczygemba Antoinette B. Coe Karl Hess David P. Zgarrick Value-added pharmacy services encompass traditional and emerging services provided by pharmacists to individual and entire populations of persons increasingly under the auspices of a public health mandate. The...
Sat Jul 20, 2019 03:00
Antibiotics, Vol. 8, Pages 99: Antifungal Agents Based on Chitosan Oligomers, ε-polylysine and Streptomyces spp. Secondary Metabolites against Three Botryosphaeriaceae Species Antibiotics doi: 10.3390/antibiotics8030099 Authors: Laura Buzón-Durán Jesús Martín-Gil Eduardo Pérez-Lebeña David Ruano-Rosa José L. Revuelta José Casanova-Gascón M. Carmen Ramos-Sánchez Pablo Martín-Ramos Grapevine trunk diseases (GTDs) are a major threat to the wine and grape industry. The...
Sat Jul 20, 2019 03:00
Microorganisms, Vol. 7, Pages 206: Engineering Synthetic Microbial Communities through a Selective Biofilm Cultivation Device for the Production of Fermented Beverages Microorganisms doi: 10.3390/microorganisms7070206 Authors: Sokny Ly F. Bajoul Kakahi Hasika Mith Chanvorleak Phat Barbara Fifani Tierry Kenne Marie-Laure Fauconnier Frank Delvigne Production of Cambodian rice wine involves complex microbial consortia. Indeed, previous studies focused on traditional...
Sat Jul 20, 2019 03:00
Cancers, Vol. 11, Pages 1016: LdrB Toxin with In Vitro and In Vivo Antitumor Activity as a Potential Tool for Cancer Gene Therapy Cancers doi: 10.3390/cancers11071016 Authors: Yaiza Jiménez-Martínez Carmen Griñán-Lisón Hoda Khaldy Ana Martín Alba Cambrils Andrea Ibáñez Grau Gema Jiménez Juan A. Marchal Houria Boulaiz Due to the high prevalence of cancer in recent years, it is necessary to develop new and more effective therapies that produce fewer side effects....
Sat Jul 20, 2019 03:00
Cancers, Vol. 11, Pages 1024: Liver Cancer Cell Lines Treated with Doxorubicin under Normoxia and Hypoxia: Cell Viability and Oncologic Protein Profile Cancers doi: 10.3390/cancers11071024 Authors: Ilse R. Dubbelboer Natasa Pavlovic Femke Heindryckx Erik Sjögren Hans Lennernäs Hepatocellular carcinoma is often treated with a combination of doxorubicin and embolization, exposing it to high concentrations and hypoxia. Separation of the possible synergistic effect of this combination...
Sat Jul 20, 2019 03:00
Cancers, Vol. 11, Pages 1017: The Molecular Hallmarks of the Serrated Pathway in Colorectal Cancer Cancers doi: 10.3390/cancers11071017 Authors: Fatima Domenica Elisa De Palma Valeria D’Argenio Jonathan Pol Guido Kroemer Maria Chiara Maiuri Francesco Salvatore Colorectal cancer (CRC) is a leading cause of cancer death worldwide. It includes different subtypes that differ in their clinical and prognostic features. In the past decade, in addition to the conventional adenoma-carcinoma...
Sat Jul 20, 2019 03:00
Cancers, Vol. 11, Pages 1023: ANGPT2 and NOS3 Polymorphisms and Clinical Outcome in Advanced Hepatocellular Carcinoma Patients Receiving Sorafenib Cancers doi: 10.3390/cancers11071023 Authors: Giorgia Marisi Elisabetta Petracci Francesco Raimondi Luca Faloppi Francesco Giuseppe Foschi Gianfranco Lauletta Massimo Iavarone Matteo Canale Martina Valgiusti Luca Maria Neri Paola Ulivi Giulia Orsi Giulia Rovesti Ranka Vukotic Fabio Conti Alessandro Cucchetti...
Sat Jul 20, 2019 03:00
Cancers, Vol. 11, Pages 1022: Platelets as Key Factors in Hepatocellular Carcinoma Cancers doi: 10.3390/cancers11071022 Authors: Natasa Pavlovic Bhavna Rani Pär Gerwins Femke Heindryckx Hepatocellular carcinoma (HCC) is a primary liver cancer that usually develops in the setting of chronic inflammation and liver damage. The hepatic microenvironment plays a crucial role in the disease development, as players such as hepatic stellate cells, resident liver macrophages (Kupffer...
Sat Jul 20, 2019 03:00
Cancers, Vol. 11, Pages 1025: Palbociclib Promotes Dephosphorylation of NPM/B23 at Threonine 199 and Inhibits Endometrial Cancer Cell Growth Cancers doi: 10.3390/cancers11071025 Authors: Chiao-Yun Lin Li-Yu Lee Tzu-Hao Wang Cheng-Lung Hsu Chia-Lung Tsai Angel Chao Chyong-Huey Lai Endometrial cancer incidence rates are growing, especially in countries with rapid socioeconomic transitions. Despite recent advances in chemotherapy, hormone therapy, and targeted therapy,...
Sat Jul 20, 2019 03:00
Nutrients, Vol. 11, Pages 1666: Association of Diet Quality and Vegetable Variety with the Risk of Cognitive Decline in Chinese Older Adults Nutrients doi: 10.3390/nu11071666 Authors: Yi-Chun Chou Meei-Shyuan Lee Jeng-Min Chiou Ta-Fu Chen Yen-Ching Chen Jen-Hau Chen Diet quality plays an important role in dementia prevention. It remains unclear how the joint effect of vegetable variety and diet quality affects cognition. This study aimed to explore the association of diet...
Sat Jul 20, 2019 03:00
Brain Sciences, Vol. 9, Pages 173: Neural Circuit and Clinical Insights from Intraoperative Recordings During Deep Brain Stimulation Surgery Brain Sciences doi: 10.3390/brainsci9070173 Authors: Anand Tekriwal Neema Moin Afshar Juan Santiago-Moreno Fiene Marie Kuijper Drew S. Kern Casey H. Halpern Gidon Felsen John A. Thompson Observations using invasive neural recordings from patient populations undergoing neurosurgical interventions have led to critical breakthroughs...
Sat Jul 20, 2019 03:00
Brain Sciences, Vol. 9, Pages 174: Common and Distinct Functional Brain Networks for Intuitive and Deliberate Decision Making Brain Sciences doi: 10.3390/brainsci9070174 Authors: Burak Erdeniz John Done Reinforcement learning studies in rodents and primates demonstrate that goal-directed and habitual choice behaviors are mediated through different fronto-striatal systems, but the evidence is less clear in humans. In this study, functional magnetic resonance imaging (fMRI) data were...
Sat Jul 20, 2019 03:00
Nanomaterials, Vol. 9, Pages 1038: Ethynylation of Formaldehyde over Binary Cu-Based Catalysts: Study on Synergistic Effect between Cu+ Species and Acid/Base Sites Nanomaterials doi: 10.3390/nano9071038 Authors: Zhipeng Wang Lijun Ban Pingfan Meng Haitao Li Yongxiang Zhao Most studies on the Cu-based catalysts in the ethynylation of formaldehyde are merely focused on the tuning of electronic configuration and dispersion of the Cu+ species. So far, little attention has been...
Sat Jul 20, 2019 03:00
IJMS, Vol. 20, Pages 3561: The Atherogenic Role of Circulating Modified Lipids in Atherosclerosis International Journal of Molecular Sciences doi: 10.3390/ijms20143561 Authors: Summerhill Grechko Yet Sobenin Orekhov Lipid accumulation in the arterial wall is a crucial event in the development of atherosclerotic lesions. Circulating low-density lipoprotein (LDL) is the major source of lipids that accumulate in the atherosclerotic plaques. It was discovered that not all...
Sat Jul 20, 2019 03:00
IJMS, Vol. 20, Pages 3560: Unique Phase Transition of Exogenous Fusion Elastin-like Polypeptides in the Solution Containing Polyethylene Glycol International Journal of Molecular Sciences doi: 10.3390/ijms20143560 Authors: Zhongqi Ge Ziyang Xiong Dandan Zhang Xialan Li Guangya Zhang Elastin-Like polypeptides (ELPs), as well-known temperature-controlled bio-macromolecules, are widely used. However, little is known about the interactions between ELPs and macromolecules, which...
Sat Jul 20, 2019 03:00
IJMS, Vol. 20, Pages 3558: Can We Still Trust Docking Results? An Extension of the Applicability of DockBench on PDBbind Database International Journal of Molecular Sciences doi: 10.3390/ijms20143558 Authors: Giovanni Bolcato Alberto Cuzzolin Maicol Bissaro Stefano Moro Mattia Sturlese The number of entries in the Protein Data Bank (PDB) has doubled in the last decade, and it has increased tenfold in the last twenty years. The availability of an ever-growing number of structures...
Sat Jul 20, 2019 03:00
IJMS, Vol. 20, Pages 3559: Autophagy: New Insights into Mechanisms of Action and Resistance of Treatment in Acute Promyelocytic leukemia International Journal of Molecular Sciences doi: 10.3390/ijms20143559 Authors: Mohammad Amin Moosavi Mojgan Djavaheri-Mergny Autophagy is one of the main cellular catabolic pathways controlling a variety of physiological processes, including those involved in self-renewal, differentiation and death. While acute promyelocytic leukemia (APL) cells...
Sat Jul 20, 2019 03:00
IJMS, Vol. 20, Pages 3552: Cardiac Insulin Resistance in Heart Failure: The Role of Mitochondrial Dynamics International Journal of Molecular Sciences doi: 10.3390/ijms20143552 Authors: Masao Saotome Takenori Ikoma Prottoy Hasan Yuichiro Maekawa Heart failure (HF) frequently coexists with conditions associated with glucose insufficiency, such as insulin resistance and type 2 diabetes mellitus (T2DM), and patients with T2DM have a significantly high incidence of HF. These two...
Sat Jul 20, 2019 03:00
Cells, Vol. 8, Pages 755: S100-EPISPOT: A New Tool to Detect Viable Circulating Melanoma Cells Cells doi: 10.3390/cells8070755 Authors: Laure Cayrefourcq Aurélie De Roeck Caroline Garcia Pierre-Emmanuel Stoebner Fanny Fichel Françoise Garima Françoise Perriard Jean-Pierre Daures Laurent Meunier Catherine Alix-Panabières Metastatic melanoma is one of the most aggressive and drug-resistant cancers with very poor overall survival. Circulating melanoma cells (CMCs)...
Sat Jul 20, 2019 03:00
Cells, Vol. 8, Pages 756: Myeloid Dendritic Cells Are Enriched in Lymph Node Tissue of Early Rheumatoid Arthritis Patients but not in At Risk Individuals Cells doi: 10.3390/cells8070756 Authors: T.H. Ramwadhdoebe M.I. Ramos K.I. Maijer K.P. van Lienden M. Maas D.M. Gerlag P.P. Tak M.C. Lebre L.G.M. van Baarsen Lymph nodes (LNs) are highly organized structures where specific immune responses are initiated by dendritic cells (DCs). We investigated the frequency...
Sat Jul 20, 2019 03:00
Cells, Vol. 8, Pages 757: The IL4I1 Enzyme: A New Player in the Immunosuppressive Tumor Microenvironment Cells doi: 10.3390/cells8070757 Authors: Valérie Molinier-Frenkel Armelle Prévost-Blondel Flavia Castellano The high metabolic needs of T lymphocytes in response to activation make them particularly vulnerable to modifications of their biochemical milieu. Immunosuppressive enzymes produced in the tumor microenvironment modify nutrient availability by catabolizing essential or...
Sat Jul 20, 2019 03:00
Pharmaceutics, Vol. 11, Pages 354: Effect of Ticagrelor, a Cytochrome P450 3A4 Inhibitor, on the Pharmacokinetics of Tadalafil in Rats Pharmaceutics doi: 10.3390/pharmaceutics11070354 Authors: Young-Guk Na Jin-Ju Byeon Hyun Wook Huh Min-Ki Kim Young G. Shin Hong-Ki Lee Cheong-Weon Cho Tadalafil is a cytochrome P450 (CYP) 3A4 substrate. Because there are few data on drug-drug interactions, it is advisable to take sufficient consideration when co-administering tadalafil...
Sat Jul 20, 2019 03:00
Molecules, Vol. 24, Pages 2640: The Neuroprotective Effects of Astaxanthin: Therapeutic Targets and Clinical Perspective Molecules doi: 10.3390/molecules24142640 Authors: Fakhri Aneva Farzaei Sobarzo-Sánchez As the leading causes of human disability and mortality, neurological diseases affect millions of people worldwide and are on the rise. Although the general roles of several signaling pathways in the pathogenesis of neurodegenerative disorders have so far been identified,...
Sat Jul 20, 2019 03:00
IJERPH, Vol. 16, Pages 2593: The Life Expectancy Gap between Registered Disabled and Non-Disabled People in Korea from 2004 to 2017 International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16142593 Authors: Jinwook Bahk Hee-Yeon Kang Young-Ho Khang This study aimed to estimate and compare life expectancy at birth among people with and without officially registered disabilities in Korea between 2004 and 2017. We used the National Health Information Database...
Sat Jul 20, 2019 03:00
Antioxidants, Vol. 8, Pages 233: Hydroxytyrosyl Oleate: Improved Extraction Procedure from Olive Oil and By-Products, and In Vitro Antioxidant and Skin Regenerative Properties Antioxidants doi: 10.3390/antiox8070233 Authors: Cinzia Benincasa Chiara La Torre Pierluigi Plastina Alessia Fazio Enzo Perri Maria Cristina Caroleo Luca Gallelli Roberto Cannataro Erika Cione Recently, we identified hydroxytyrosyl oleate (HtyOle) in the by-products of olive oil, pomace...
Sat Jul 20, 2019 03:00
Antioxidants, Vol. 8, Pages 232: Characterization of an Antioxidant and Antimicrobial Extract from Cool Climate, White Grape Marc Antioxidants doi: 10.3390/antiox8070232 Authors: Kenneth J. Olejar Arianna Ricci Simon Swift Zoran Zujovic Keith C. Gordon Bruno Fedrizzi Andrea Versari Paul A. Kilmartin Valorization of agricultural waste has become increasingly important. Wastes generated by wineries are high in phenolic compounds with antioxidant and antibacterial properties,...
Sat Jul 20, 2019 03:00
Antioxidants, Vol. 8, Pages 234: Monitoring of Chlorogenic Acid and Antioxidant Capacity of Solanum melongena L. (Eggplant) under Different Heat and Storage Treatments Antioxidants doi: 10.3390/antiox8070234 Authors: Petra Šilarová Lila Boulekbache-Makhlouf Federica Pellati Lenka Česlová Solanum melongena L., also known as eggplant, is a widely consumed vegetable and it is well-known for its beneficial antioxidant properties, due to phenolic compounds. In this work, the influence...
Sat Jul 20, 2019 03:00
IJMS, Vol. 20, Pages 3556: Elucidation of the Molecular Mechanism Underlying Lippia citriodora(Lim.)-Induced Relaxation and Anti-Depression International Journal of Molecular Sciences doi: 10.3390/ijms20143556 Authors: Mouad Sabti Kazunori Sasaki Chemseddoha Gadhi Hiroko Isoda Lippia citriodora ethanolic extract (VEE) and verbascoside (Vs), a phenypropanoid glycoside, have been demonstrated to exert relaxant and anxiolytic properties. However, the molecular mechanisms behind...
Sat Jul 20, 2019 03:00
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