IJMS, Vol. 20, Pages 3554: Sphingolipid-Transporting Proteins as Cancer Therapeutic Targets International Journal of Molecular Sciences doi: 10.3390/ijms20143554 Authors: Doaa Samaha Housam H. Hamdo Max Wilde Kevin Prause Christoph Arenz The understanding of the role of sphingolipid metabolism in cancer has tremendously increased in the past ten years. Many tumors are characterized by imbalances in sphingolipid metabolism. In many cases, disorders of sphingolipid metabolism...
Sat Jul 20, 2019 03:00
IJMS, Vol. 20, Pages 3557: RcAP1, a Homolog of APETALA1, is Associated with Flower Bud Differentiation and Floral Organ Morphogenesis in Rosa chinensis International Journal of Molecular Sciences doi: 10.3390/ijms20143557 Authors: Yu Han Aoying Tang Jiayao Yu Tangren Cheng Jia Wang Weiru Yang Huitang Pan Qixiang Zhang Rosa chinensis is one of the most popular flower plants worldwide. The recurrent flowering trait greatly enhances the ornamental value of roses, and...
Sat Jul 20, 2019 03:00
IJMS, Vol. 20, Pages 3555: Role of Tricellular Tight Junction Protein Lipolysis-Stimulated Lipoprotein Receptor (LSR) in Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms20143555 Authors: Takayuki Kohno Takumi Konno Takashi Kojima Maintaining a robust epithelial barrier requires the accumulation of tight junction proteins, LSR/angulin-1 and tricellulin, at the tricellular contacts. Alterations in the localization of these proteins temporarily cause epithelial...
Sat Jul 20, 2019 03:00
Water, Vol. 11, Pages 1505: Assessing the Self-Purification Capacity of Surface Waters in Lake Baikal Watershed Water doi: 10.3390/w11071505 Authors: Mikhail Yu. Semenov Yuri M. Semenov Anton V. Silaev Larisa A. Begunova The removal of trace metals (TM), dissolved organic carbon (DOC), mineral nitrogen (Nmin.), and polycyclic aromatic hydrocarbons (PAHs) from the water of Lake Baikal and its tributaries was evaluated. The contaminant removal rate (CRR) and the contaminant removal...
Sat Jul 20, 2019 03:00
JCM, Vol. 8, Pages 1064: Clinical Trajectories and Causes of Death in Septic Patients with a Low APACHE II Score Journal of Clinical Medicine doi: 10.3390/jcm8071064 Authors: Chun-Ta Huang Sheng-Yuan Ruan Yi-Ju Tsai Shih-Chi Ku Chong-Jen Yu Clinical course and mortality in septic patients with low disease severity remain poorly understood and is worth further investigation. We enrolled septic patients admitted to intensive care units (ICUs) between 2010 and 2014 with Acute...
Sat Jul 20, 2019 03:00
JCM, Vol. 8, Pages 1066: Etelcalcetide in Patients on Hemodialysis with Severe Secondary Hyperparathyroidism. Multicenter Study in “Real Life” Journal of Clinical Medicine doi: 10.3390/jcm8071066 Authors: Domenico Russo Rocco Tripepi Fabio Malberti Biagio Di Iorio Bernadette Scognamiglio Luca Di Lullo Immacolata Gaia Paduano Giovanni Luigi Tripepi Vincenzo Antonio Panuccio Etelcalcetide is a new calcimimetic indicated for the treatment of secondary hyperparathyroidism...
Sat Jul 20, 2019 03:00
JCM, Vol. 8, Pages 1067: The Role of a “Treat-to-Target” Approach in the Long-Term Renal Outcomes of Patients with Gout Journal of Clinical Medicine doi: 10.3390/jcm8071067 Authors: Woo-Joong Kim Jung Soo Song Sang Tae Choi Background: Although gout is accompanied by the substantial burden of kidney disease, there are limited data to assess renal function as a therapeutic target. This study evaluated the importance of implementing a “treat-to-target” approach...
Sat Jul 20, 2019 03:00
JCM, Vol. 8, Pages 1065: Nutritional Risk Screening and Assessment Journal of Clinical Medicine doi: 10.3390/jcm8071065 Authors: Emilie Reber Filomena Gomes Maria F. Vasiloglou Philipp Schuetz Zeno Stanga Malnutrition is an independent risk factor that negatively influences patients’ clinical outcomes, quality of life, body function, and autonomy. Early identification of patients at risk of malnutrition or who are malnourished is crucial in order to start a timely...
Sat Jul 20, 2019 03:00
JCM, Vol. 8, Pages 1068: Cost–Utility of Mindfulness-Based Stress Reduction for Fibromyalgia versus a Multicomponent Intervention and Usual Care: A 12-Month Randomized Controlled Trial (EUDAIMON Study) Journal of Clinical Medicine doi: 10.3390/jcm8071068 Authors: Adrián Pérez-Aranda Francesco D’Amico Albert Feliu-Soler Lance M. McCracken María T. Peñarrubia-María Laura Andrés-Rodríguez Natalia Angarita-Osorio Martin Knapp Javier García-Campayo Juan V. Luciano ...
Sat Jul 20, 2019 03:00
Toxins, Vol. 11, Pages 425: The Dual α-Amidation System in Scorpion Venom Glands Toxins doi: 10.3390/toxins11070425 Authors: Gustavo Delgado-Prudencio Lourival D. Possani Baltazar Becerril Ernesto Ortiz Many peptides in scorpion venoms are amidated at their C-termini. This post-translational modification is paramount for the correct biological function of ion channel toxins and antimicrobial peptides, among others. The discovery of canonical amidation sequences in transcriptome-derived...
Sat Jul 20, 2019 03:00
Toxins, Vol. 11, Pages 426: Comparative Analysis of Listeria monocytogenes Plasmids and Expression Levels of Plasmid-Encoded Genes during Growth under Salt and Acid Stress Conditions Toxins doi: 10.3390/toxins11070426 Authors: Patricia Hingston Thomas Brenner Lisbeth Truelstrup Hansen Siyun Wang Listeria monocytogenes strains are known to harbour plasmids that confer resistance to sanitizers, heavy metals, and antibiotics; however, very little research has been conducted into...
Sat Jul 20, 2019 03:00
Nutrients, Vol. 11, Pages 1661: Acute Caffeine and Coconut Oil Intake, Isolated or Combined, Does Not Improve Running Times of Recreational Runners: A Randomized, Placebo-Controlled and Crossover Study Nutrients doi: 10.3390/nu11071661 Authors: Gabrielle de Lima Borba Julianne Soares de Freitas Batista Ludmilla Marques Queiroz Novais Myrnzzia Beatriz Silva João Batista da Silva Júnior Paulo Gentil Ana Clara Baretto Marini Bruna Melo Giglio Gustavo Duarte Pimentel ...
Sat Jul 20, 2019 03:00
Nutrients, Vol. 11, Pages 1664: Lipotoxicity in Kidney, Heart, and Skeletal Muscle Dysfunction Nutrients doi: 10.3390/nu11071664 Authors: Hiroshi Nishi Takaaki Higashihara Reiko Inagi Dyslipidemia is a common nutritional and metabolic disorder in patients with chronic kidney disease. Accumulating evidence supports the hypothesis that prolonged metabolic imbalance of lipids leads to ectopic fat distribution in the peripheral organs (lipotoxicity), including the kidney, heart, and...
Sat Jul 20, 2019 03:00
Nutrients, Vol. 11, Pages 1662: A Dietary Intervention with Reduction of Starch and Sucrose Leads to Reduced Gastrointestinal and Extra-Intestinal Symptoms in IBS Patients Nutrients doi: 10.3390/nu11071662 Authors: Clara Nilholm Bodil Roth Bodil Ohlsson Patients with irritable bowel syndrome (IBS) exhibit low-grade inflammation and increased gut permeability. Dietary sugar has been shown to contribute to low-grade inflammation and increased gut permeability, and to correlate with...
Sat Jul 20, 2019 03:00
Nutrients, Vol. 11, Pages 1663: Predicting and Testing Bioavailability of Magnesium Supplements Nutrients doi: 10.3390/nu11071663 Authors: Laura Blancquaert Chris Vervaet Wim Derave Despite the presumption of the beneficial effects of magnesium supplementation, little is known about the pharmacokinetics of different magnesium formulations. We aimed to investigate the value of two in vitro approaches to predict bioavailability of magnesium and to validate this in subsequent in vivo...
Sat Jul 20, 2019 03:00
Nutrients, Vol. 11, Pages 1660: Biological Effect of Soy Isoflavones in the Prevention of Civilization Diseases Nutrients doi: 10.3390/nu11071660 Authors: Marzena Pabich Małgorzata Materska Scientific advancements in recent years have shed new light on the relationship between diet and human health. Nutrients play an important role in the prevention of many civilization diseases, such as osteoporosis, type II diabetes, hypercholesterolemia, and cardiovascular diseases. The biological...
Sat Jul 20, 2019 03:00
Nutrients, Vol. 11, Pages 1665: Lupin Peptide T9 (GQEQSHQDEGVIVR) Modulates the Mutant PCSK9D374Y Pathway: in vitro Characterization of its Dual Hypocholesterolemic Behavior Nutrients doi: 10.3390/nu11071665 Authors: Carmen Lammi Carlotta Bollati Davide Lecca Maria Pia Abbracchio Anna Arnoldi GQEQSHQDEGVIVR (T9) is a peptide originated by the tryptic digestion of lupin β-conglutin that is absorbed in human intestinal Caco-2 cells. A previous study has shown that...
Sat Jul 20, 2019 03:00
Diagnostics, Vol. 9, Pages 80: Pathological Mechanisms Underlying Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Diagnostics doi: 10.3390/diagnostics9030080 Authors: Daniel Missailidis Sarah J. Annesley Paul R. Fisher The underlying molecular basis of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is not well understood. Characterized by chronic, unexplained fatigue, a disabling payback following exertion (“post-exertional malaise”), and variably...
Sat Jul 20, 2019 03:00
Viruses, Vol. 11, Pages 666: Reverse Genetics of RNA Viruses: ISA-Based Approach to Control Viral Population Diversity without Modifying Virus Phenotype Viruses doi: 10.3390/v11070666 Authors: Jean-Sélim Driouich Gregory Moureau Xavier de Lamballerie Antoine Nougairède Reverse genetic systems are essential for the study of RNA viruses. Infectious clones remain the most widely used systems to manipulate viral genomes. Recently, a new PCR-based method called ISA (infectious subgenomic...
Sat Jul 20, 2019 03:00
IJMS, Vol. 20, Pages 3553: Purification, Characterization of Two Polysaccharides from Pinelliae Rhizoma Praeparatum Cum Alumine and Their Anti-Inflammatory Effects on Mucus Secretion of Airway Epithelium International Journal of Molecular Sciences doi: 10.3390/ijms20143553 Authors: Meibian Hu Yujie Liu Li Wang Jiaolong Wang Lin Li Chunjie Wu Pinelliae Rhizoma Praeparatum cum Alumine (PRPCA) is an important traditional processed herbal medicine mainly used for treating...
Sat Jul 20, 2019 03:00
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