JCM, Vol. 9, Pages 315: Increased Cancer Incidence Following up to 15 Years after Cardiac Catheterization in Infants under One Year between 1980 and 1998—A Single Center Observational Study Journal of Clinical Medicine doi: 10.3390/jcm9020315 Authors: Stern Seidenbusch Hapfelmeier Meierhofer Naumann Schmid Spix Ewert Objective: To evaluate the incidence of cancer within the first 15 years of life in children who underwent cardiac catheterization under the...
JCM, Vol. 9, Pages 311: Peripheral Blood Mononuclear Cells and Platelets Mitochondrial Dysfunction, Oxidative Stress, and Circulating mtDNA in Cardiovascular Diseases Journal of Clinical Medicine doi: 10.3390/jcm9020311 Authors: Alfatni Riou Charles Meyer Barnig Andres Lejay Talha Geny Cardiovascular diseases (CVDs) are devastating disorders and the leading cause of mortality worldwide. The pathophysiology of cardiovascular diseases is complex and multifactorial...
JCM, Vol. 9, Pages 310: Eph/ephrin Signaling and Biology of Mesenchymal Stromal/Stem Cells Journal of Clinical Medicine doi: 10.3390/jcm9020310 Authors: Alfaro Rodríguez-Sosa Zapata Mesenchymal stromal/stem cells (MSCs) have emerged as important therapeutic agents, owing to their easy isolation and culture, and their remarkable immunomodulatory and anti-inflammatory properties. However, MSCs constitute a heterogeneous cell population which does not express specific cell markers...
JCM, Vol. 9, Pages 307: Changes in the Physical Function and Psychological Distress from Pre-Implant to 1, 6, and 12 Months Post-Implant in Patients Undergoing Implantable Cardioverter Defibrillator Therapy Journal of Clinical Medicine doi: 10.3390/jcm9020307 Authors: Kim Park Choi Kim On Shin Choi Heo Recipients of implantable cardioverter-defibrillator (ICD) therapy in Western countries often experience distressful physical and psychological adjustments....
JCM, Vol. 9, Pages 312: Skin Cutibacterium acnes Mediates Fermentation to Suppress the Calcium Phosphate-Induced Itching: A Butyric Acid Derivative with Potential for Uremic Pruritus Journal of Clinical Medicine doi: 10.3390/jcm9020312 Authors: Keshari Wang Herr Wang Yang Chuang Chen Huang Pruritus and inflammation associated with accumulation of calcium phosphate (CaP) under the skin are common problems among dialysis patients with chronic kidney disease...
JCM, Vol. 9, Pages 308: Primary Hyperparathyroidism in Sickle Cell Disease: An Unknown Complication of the Disease in Adulthood Journal of Clinical Medicine doi: 10.3390/jcm9020308 Authors: Denoix Bomahou Clavier Ribeil Lionnet Bartolucci Courbebaisse Pouchot Arlet Primary hyperparathyroidism (pHPT) is the third most common endocrine disorder and usually affects patients between 60 and 70 years of age. To our knowledge, this condition has never been studied...
JCM, Vol. 9, Pages 306: Changes in Indocyanine Green Lymphography Patterns after Physical Treatment in Secondary Upper Limb Lymphedema Journal of Clinical Medicine doi: 10.3390/jcm9020306 Authors: Medina-Rodríguez de-la-Casa-Almeida González Martín Hermida Anllo Medrano-Sánchez Indocyanine green (ICG) lymphography is used to evaluate the lymphatic function before and after pneumatic compression or post-manual lymphatic drainage. The aim of this study was to ascertain...
JCM, Vol. 9, Pages 309: Predictors of Mental Health Outcomes in Road Traffic Accident Survivors Journal of Clinical Medicine doi: 10.3390/jcm9020309 Authors: Kovacevic Miskulin Degmecic Vcev Leovic Sisljagic Simic Palenkic Vcev Miskulin Mental health outcomes of road traffic accidents (RTAs) are always investigated in assessments of those involved. The aim of this study was to investigate the psychological consequences and associated factors in all...
JCM, Vol. 9, Pages 305: Arginase 2 Deficiency Promotes Neuroinflammation and Pain Behaviors Following Nerve Injury in Mice Journal of Clinical Medicine doi: 10.3390/jcm9020305 Authors: Yin Phạm Shin Shin Kang Lee Lee Kim Kim Hong Kim Microglia, the resident macrophages, act as the first and main form of active immune defense in the central nervous system. Arginase 2 (Arg2) is an enzyme involved in L-arginine metabolism and is expressed in macrophages...
JCM, Vol. 9, Pages 304: Surrogate Markers of Neutrophil Extracellular Trap Formation are Associated with Ischemic Outcomes and Platelet Activation after Peripheral Angioplasty and Stenting Journal of Clinical Medicine doi: 10.3390/jcm9020304 Authors: Demyanets Stojkovic Mauracher Kopp Wojta Thaler Panzer Gremmel Neutrophil extracellular traps (NETs) are supposed to play a central role in atherothrombosis. We measured circulating citrullinated histone H3 (H3Cit)...
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Metabolites, Vol. 10, Pages 43: Current Practice in Untargeted Human Milk Metabolomics Metabolites doi: 10.3390/metabo10020043 Authors: Ten-Doménech Ramos-Garcia Piñeiro-Ramos Gormaz Parra-Llorca Vento Kuligowski Quintás Human milk (HM) is considered the gold standard for infant nutrition. HM contains macro- and micronutrients, as well as a range of bioactive compounds (hormones, growth factors, cell debris, etc.). The analysis of the complex and dynamic...
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MPs, Vol. 3, Pages 11: A Simple and Reliable Protocol for the Preparation and Culturing of Fresh Surgically Resected Human Glioblastoma Tissue Methods and Protocols doi: 10.3390/mps3010011 Authors: Kan Drummond Hunn Williams O’Brien Monif Glioblastoma is a heterogeneous glial cell malignancy with extremely high morbidity and mortality. Current treatment is limited and provide minimal therapeutic efficacy. Previous studies were reliant on cell lines that do not accurately...
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Microorganisms, Vol. 8, Pages 157: Nitrogen Preferences during Alcoholic Fermentation of Different Non-Saccharomyces Yeasts of Oenological Interest Microorganisms doi: 10.3390/microorganisms8020157 Authors: Roca-Mesa Sendra Mas Beltran Torija Non-Saccharomyces yeasts have long been considered spoilage microorganisms. Currently, oenological interest in those species is increasing, mostly due to their positive contribution to wine quality. In this work, the fermentative...
Microorganisms, Vol. 8, Pages 156: A MATE Transporter is Involved in Pathogenicity and IAA Homeostasis in the Hyperplastic Plant Pathogen Pseudomonas savastanoi pv. nerii Microorganisms doi: 10.3390/microorganisms8020156 Authors: Tegli Bini Calamai Cerboneschi Biancalani During the last years, many evidences have been accumulating about the phytohormone indole-3-acetic acid (IAA) as a multifaceted compound in the microbial world, with IAA playing a role as a bacterial...
Microorganisms, Vol. 8, Pages 155: Acknowledgement to Reviewers of Microorganismsin 2019 Microorganisms doi: 10.3390/microorganisms8020155 Authors: Microorganisms Editorial Office The editorial team greatly appreciates the reviewers who have dedicated their considerable time and expertise to the journal’s rigorous editorial process over the past 12 months, regardless of whether the papers are finally published or not [...]
Microorganisms, Vol. 8, Pages 154: Candida albicans Antifungal Resistance and Tolerance in Bloodstream Infections: The Triad Yeast-Host-Antifungal Microorganisms doi: 10.3390/microorganisms8020154 Authors: Costa-de-Oliveira Rodrigues Candida albicans represents the most frequent isolated yeast from bloodstream infections. Despite the remarkable progress in diagnostic and therapeutic approaches, these infections continue to be a critical challenge in intensive care units worldwide....
Microorganisms, Vol. 8, Pages 152: SYN-007, an Orally Administered Beta-Lactamase Enzyme, Protects the Gut Microbiome from Oral Amoxicillin/Clavulanate without Adversely Affecting Antibiotic Systemic Absorption in Dogs Microorganisms doi: 10.3390/microorganisms8020152 Authors: Connelly Fanelli Hasan Colwell Kaleko Beta-lactamases, enzymes produced by bacteria to degrade beta-lactam antibiotics, have been harnessed as therapeutics to protect the gut microbiome from damage...
Microorganisms, Vol. 8, Pages 150: Distribution of Phototrophic Purple Nonsulfur Bacteria in Massive Blooms in Coastal and Wastewater Ditch Environments Microorganisms doi: 10.3390/microorganisms8020150 Authors: Hiraishi Nagao Yonekawa Umekage Kikuchi Eki Hirose The biodiversity of phototrophic purple nonsulfur bacteria (PNSB) in comparison with purple sulfur bacteria (PSB) in colored blooms and microbial mats that developed in coastal mudflats and pools and...
Microorganisms, Vol. 8, Pages 153: Genome Sequencing of Pantoea agglomerans C1 Provides Insights into Molecular and Genetic Mechanisms of Plant Growth-Promotion and Tolerance to Heavy Metals Microorganisms doi: 10.3390/microorganisms8020153 Authors: Luziatelli Ficca Cardarelli Melini Cavalieri Ruzzi Distinctive strains of Pantoea are used as soil inoculants for their ability to promote plant growth. Pantoea agglomerans strain C1, previously isolated from the phyllosphere...
Microorganisms, Vol. 8, Pages 151: Feeding Strategies of Two-Stage Fed-Batch Cultivation Processes for Microbial Lipid Production from Sugarcane Top Hydrolysate and Crude Glycerol by the Oleaginous Red Yeast Rhodosporidiobolus fluvialis Microorganisms doi: 10.3390/microorganisms8020151 Authors: Poontawee Limtong Microbial lipids are able to produce from various raw materials including lignocellulosic biomass by the effective oleaginous microorganisms using different cultivation...
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Molecules, Vol. 25, Pages 479: Synthesis, Anticancer Activity, and Preliminary Pharmacokinetic Evaluation of 4,4-Disubstituted Curcuminoid 2,2-bis(Hydroxymethyl)Propionate Derivatives Molecules doi: 10.3390/molecules25030479 Authors: Lee Hou Yang Lin Chang Lee Kuo Hsieh Compound 1 is a curcumin di-O-2,2-bis(hydroxymethyl)propionate that shows significant in vitro and in vivo inhibitory activity against MDA-MB-231 cells with eight to ten-fold higher potency...
Molecules, Vol. 25, Pages 478: In vivo and in vitro Evaluation of the Protective Effects of Hesperidin in Lipopolysaccharide-Induced Inflammation and Cytotoxicity of Cell Molecules doi: 10.3390/molecules25030478 Authors: Al-Rikabi Al-Shmgani Dewir El-Hendawy (1) Background: Plant flavonoids are efficient in preventing and treating various diseases. This study aimed to evaluate the ability of hesperidin, a flavonoid found in citrus fruits, in inhibiting lipopolysaccharide...
Molecules, Vol. 25, Pages 476: Cytotoxic Action of Artemisinin and Scopoletin on Planktonic Forms and on Biofilms of Candida Species Molecules doi: 10.3390/molecules25030476 Authors: Das Czuni Báló Papp Gazdag Papp Kőszegi We investigated the antifungal activities of purified plant metabolites artemisinin (Ar) and scopoletin (Sc) including inhibition, effects on metabolic activities, viability, and oxidative stress on planktonic forms and on preformed biofilms...
Molecules, Vol. 25, Pages 477: Extraction of Galphimines from Galphimia glauca with Supercritical Carbon Dioxide Molecules doi: 10.3390/molecules25030477 Authors: Sánchez Solis Zamilpa Morales García Ferrer Tortoriello The anti-depressive and anxiolytic effect of galphimine B (isolated from Galphimia glauca) has been demonstrated by researchers. Therefore, it is necessary to explore extraction techniques that produce materials with adequate quality for pharmaceutical...
Molecules, Vol. 25, Pages 474: Environmental Durability Enhancement of Natural Fibres Using Plastination: A Feasibility Investigation on Bamboo Molecules doi: 10.3390/molecules25030474 Authors: Dhir Rashidi Bogyo Ryde Pakpour Milani Natural fibers are gaining wide attention due to their much lower carbon footprint and economic factors compared to synthetic fibers. The moisture affinity of these lignocellulosic fibres, however, is still one of the main challenges...
Molecules, Vol. 25, Pages 470: Pestalotiones A–D: Four New Secondary Metabolites from the Plant Endophytic Fungus Pestalotiopsis Theae Molecules doi: 10.3390/molecules25030470 Authors: Guo Lin Niu Liu Liu Two new xanthone derivatives, pestalotiones A (1) and B (2), one new diphenyl ketone riboside, pestalotione C (7), and one new diphenyl ether, pestalotione D (8), along with five known compounds isosulochrin dehydrate (3), 3,8-dihydroxy-6-methyl-9-oxo-9H-xanthene-1-carboxylate...
Molecules, Vol. 25, Pages 475: OcUGT1-Catalyzing Glycodiversification of Steroids through Glucosylation and Transglucosylation Actions Molecules doi: 10.3390/molecules25030475 Authors: Yan-Li Xu Jian-Qiang Kong Steroidal glycosides are important sources of innovative drugs. The increased diversification of steroidal glycosides will expand the probability of discovering active molecules. It is an efficient approach to diversify steroidal glycosides by using steroidal glycosyltransferases....
Molecules, Vol. 25, Pages 472: Impact of Botrytis cinerea Contamination on the Characteristics and Foamability of Yeast Macromolecules Released during the Alcoholic Fermentation of a Model Grape Juice Molecules doi: 10.3390/molecules25030472 Authors: Marchal Salmon Gonzalez Kemp Vrigneau Williams Doco Botrytis cinerea is a fungal pathogen responsible for the decrease in foamability of sparkling wines. The proteolysis of must proteins originating from botrytized...
Molecules, Vol. 25, Pages 471: Comparison on Reduction of VOCs Emissions from Radiata Pine (Pinus Radiata D. Don) between Sodium Bicarbonate and Ozone Treatments Molecules doi: 10.3390/molecules25030471 Authors: Qin Qi Wang Cheng Li Huang Liu Volatile organic compounds (VOCs) in wood furniture are an important factor that affects indoor air quality. In this study, radiata pine (Pinus radiata D. Don) was treated with sodium bicarbonate and ozone aqueous solution...
Molecules, Vol. 25, Pages 473: NMR Relaxation Measurements on Complex Samples Based on Real-Time Pure Shift Techniques Molecules doi: 10.3390/molecules25030473 Authors: Lin Zhan Li Huang Chen Longitudinal spin-lattice relaxation (T1) and transverse spin-spin relaxation (T2) reveal valuable information for studying molecular dynamics in NMR applications. Accurate relaxation measurements from conventional 1D proton spectra are generally subject to challenges of spectral...
Molecules, Vol. 25, Pages 468: Process Development and Synthesis of Process-Related Impurities of an Efficient Scale-Up Preparation of 5,2′-Dibromo-2,4′,5′-Trihydroxy Diphenylmethanone as a New Acute Pyelonephritis Candidate Drug Molecules doi: 10.3390/molecules25030468 Authors: Feng Cui Li Wu Lei Based on a foregoing gram-scale laboratory process, an efficient scale-up preparation process of 5,2′-dibromo-2,4′,5′-trihydroxydiphenylmethanone...
Molecules, Vol. 25, Pages 469: Local Electronic Structure in AlN Studied by Single-Crystal 27Al and 14N NMR and DFT Calculations Molecules doi: 10.3390/molecules25030469 Authors: Otto E. O. Zeman Igor L. Moudrakovski Carsten Hartmann Sylvio Indris Thomas Bräuniger Both the chemical shift and quadrupole coupling tensors for 14 N and 27 Al in the wurtzite structure of aluminum nitride have been determined to high precision by single-crystal NMR spectroscopy....
Molecules, Vol. 25, Pages 467: Preclinical Pharmacological Activities of Epigallocatechin-3-gallate in Signaling Pathways: An Update on Cancer Molecules doi: 10.3390/molecules25030467 Authors: Sharifi-Rad Pezzani Redaelli Zorzan Imran Ahmed Khalil Salehi Sharopov Cho Sharifi-Rad Epigallocatechin gallate (EGCG) is the main bioactive component of catechins predominantly present in svarious types of teas. EGCG is well known for a wide spectrum of biological...
Molecules, Vol. 25, Pages 465: Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani Molecules doi: 10.3390/molecules25030465 Authors: Cabral Pomel Cojean Amado Loiseau Cristiano A chemically diverse range of novel tetraoxanes was synthesized and evaluated in vitro against intramacrophage amastigote forms of Leishmania donovani. All 15 tested tetraoxanes displayed activity, with IC50 values ranging from 2 to 45 µm. The...
Molecules, Vol. 25, Pages 460: Signalling and Bioactive Metabolites from Streptomyces sp. RK44 Molecules doi: 10.3390/molecules25030460 Authors: Fang Maglangit Wu Ebel Kyeremeh Andersen Annang Pérez-Moreno Reyes Deng Streptomyces remains one of the prolific sources of structural diversity, and a reservoir to mine for novel natural products. Continued screening for new Streptomyces strains in our laboratory led to the isolation of Streptomyces sp....
Molecules, Vol. 25, Pages 462: Triterpenoid Saponin and Lignan Glycosides from the Traditional Medicine Elaeagnus angustifolia Flowers and Their Cytotoxic Activities Molecules doi: 10.3390/molecules25030462 Authors: Han Chen Liu Cui Yuan A new triterpenoid saponin, named terpengustifol A (1), and two new lignan glucosides, phengustifols A and B (2 and 3), were isolated from the flowers of Elaeagnus angustifolia. Their structures were determined by the extensive analysis...
Molecules, Vol. 25, Pages 459: Interaction and Kinetics Study of the Co-Gasification of High-solid Anaerobic Digestate and Lignite Molecules doi: 10.3390/molecules25030459 Authors: Chang Zhang Cao Ma Wang Li Li This study aims at investigating the interaction and kinetics behavior of the co-gasification of digestate and lignite. The co-pyrolysis performances of digestate and lignite blended by dry process were better than that blended by wet process, while the...
Molecules, Vol. 25, Pages 466: Effects of Lycium barbarum L. Polysaccharides on Inflammation and Oxidative Stress Markers in a Pressure Overload-Induced Heart Failure Rat Model Molecules doi: 10.3390/molecules25030466 Authors: Pop Berce Ghibu Scurtu Sorițău Login Kiss Ștefan Fizeșan Silaghi Mocan Crișan Loghin Mogoșan Despite recent advances in disease management and prevention, heart failure (HF) prevalence is still high. Hypertension,...
Molecules, Vol. 25, Pages 461: Volatile Flavor Compounds in Cheese as Affected by Ruminant Diet Molecules doi: 10.3390/molecules25030461 Authors: Ianni Bennato Martino Grotta Martino Extensive research has been conducted concerning the determination and characterization of volatile compounds contributing to aroma and flavor in cheese. Considerable knowledge has been accumulated on the understanding of the mechanisms through which these compounds are formed during ripening,...
Molecules, Vol. 25, Pages 464: Grapevine Green Pruning Residues as a Promising and Sustainable Source of Bioactive Phenolic Compounds Molecules doi: 10.3390/molecules25030464 Authors: Acquadro Appleton Marengo Bicchi Sgorbini Mandrone Gai Peiretti Cagliero Rubiolo Green pruning residues (GPRs) and leaves from 16 red and white Vitis vinifera L. cultivars from Piedmont (Italy) were studied. The investigated samples were extracted by ultrasound-assisted...
Molecules, Vol. 25, Pages 458: Comparison of the Effects of Different Food-Grade Emulsifiers on the Properties and Stability of a Casein-Maltodextrin-Soybean Oil Compound Emulsion Molecules doi: 10.3390/molecules25030458 Authors: Liu Wei Deng Dong Zhang Tang Li Liu Zhang The improvement of food-grade emulsifiers in the properties and stability of complex emulsion has attracted much interest. In this study, the effects of six food-grade emulsifiers with...
Molecules, Vol. 25, Pages 463: Evaluation of a 68Ga-Labeled DOTA-Tetrazine as a PET Alternative to 111In-SPECT Pretargeted Imaging Molecules doi: 10.3390/molecules25030463 Authors: Edem Jørgensen Nørregaard Rossin Yazdani Valliant Robillard Herth Kjaer The bioorthogonal reaction between a tetrazine and strained transcyclooctene (TCO) has garnered success in pretargeted imaging. This reaction was first validated in nuclear imaging using an 111In-labeled...
Molecules, Vol. 25, Pages 457: Neo-Aplysiatoxin A Isolated from Okinawan Cyanobacterium Moorea Producens Molecules doi: 10.3390/molecules25030457 Authors: Kawaguchi Satake Zhang Xiao Fukuoka Uchida Nagai A new aplysiatoxin derivative, neo-aplysiatoxin A (1), along with seven known compounds, neo-debromoaplysiatoxin A (2), dolastatin 3 (3), lyngbic acid (4), malyngamide M (5), hermitamide A (6), (−)-loliolide (7), and (+)-epiloliolide (8), was isolated...
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MTI, Vol. 4, Pages 2: Acknowledgement to Reviewers of MTI in 2019 Multimodal Technologies and Interaction doi: 10.3390/mti4010002 Authors: MTI Editorial Office The editorial team greatly appreciates [...]
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Nanomaterials, Vol. 10, Pages 195: Composite Nanogels Based on Zeolite-Poly(ethylene glycol) Diacrylate for Controlled Drug Delivery Nanomaterials doi: 10.3390/nano10020195 Authors: Spatarelu (Radu) Chiriac Cursaru Iordache Gavrila Cojocaru Botez Trica Sarbu Teodorescu Tofan Perrin Zaharia This study presents the design of novel composites nanogels, based on poly(ethylene glycol) diacrylate and natural zeolite particles, that are able...
Nanomaterials, Vol. 10, Pages 194: Binder-Free Nickel Oxide Lamellar Layer Anchored CoOx Nanoparticles on Nickel Foam for Supercapacitor Electrodes Nanomaterials doi: 10.3390/nano10020194 Authors: Chen Zhong Shen Wang Liu Chen Yang Zhang He To enhance the connection of electroactive materials/current collector and accelerate the transport efficiency of the electrons, a binder-free electrode composed of nickel oxide anchored CoOx nanoparticles on modified...
Nanomaterials, Vol. 10, Pages 190: Immunological and Toxicological Considerations for the Design of Liposomes Nanomaterials doi: 10.3390/nano10020190 Authors: Inglut Sorrin Kuruppu Vig Cicalo Ahmad Huang Liposomes hold great potential as gene and drug delivery vehicles due to their biocompatibility and modular properties, coupled with the major advantage of attenuating the risk of systemic toxicity from the encapsulated therapeutic agent. Decades of research...
Nanomaterials, Vol. 10, Pages 193: Post-Synthetic Derivatization of Graphitic Carbon Nitride with Methanesulfonyl Chloride: Synthesis, Characterization and Photocatalysis Nanomaterials doi: 10.3390/nano10020193 Authors: Praus Smýkalová Foniok Velíšek Cvejn Žádný Storch Bulk graphitic carbon nitride (CN) was synthetized by heating of melamine at 550 °C, and the exfoliated CN (ExCN) was prepared by heating of CN at 500 °C. Sulfur-doped CN was synthesized...
Nanomaterials, Vol. 10, Pages 192: Stability and Dynamic Aggregation of Bare and Stabilized Zero-Valent Iron Nanoparticles under Variable Solution Chemistry Nanomaterials doi: 10.3390/nano10020192 Authors: Ibrahim Awad Al-Farraj Al-Turki Surface modification of nanoscale zero-valent iron (nZVI) using polymer stabilizers (e.g., sodium carboxymethyl cellulose, CMC) is usually used to minimize aggregation, increase stability, and enhance transport of nZVI. We investigated the...
Nanomaterials, Vol. 10, Pages 191: Nonstoichiometric Cu0.6Ni0.4Co2O4 Nanowires as an Anode Material for High Performance Lithium Storage Nanomaterials doi: 10.3390/nano10020191 Authors: Li Jiang Liao Feng Liu Li Transition metal oxide is one of the most promising anode materials for lithium-ion batteries. Generally, the electrochemical property of transition metal oxides can be improved by optimizing their element components and controlling their nano-architecture....
Nanomaterials, Vol. 10, Pages 188: Aromatic Hyperbranched Polyester/RTM6 Epoxy Resin for EXTREME Dynamic Loading Aeronautical Applications Nanomaterials doi: 10.3390/nano10020188 Authors: Zotti Elmahdy Zuppolini Borriello Verleysen Zarrelli The effects of the addition of an aromatic hyperbranched polyester (AHBP) on thermal, mechanical, and fracture toughness properties of a thermosetting resin system were investigated. AHBP filler, synthesized by using a bulk poly-condensation...
Nanomaterials, Vol. 10, Pages 189: LiAl5O8:Fe3+ and LiAl5O8:Fe3+, Nd3+ as a New Luminescent Nanothermometer Operating in 1st Biological Optical Window Nanomaterials doi: 10.3390/nano10020189 Authors: Kniec Tikhomirov Pozniak Ledwa Marciniak New types of contactless luminescence nanothermometers, namely, LiAl5O8:Fe3+ and LiAl5O8:Fe3+, Nd3+ are presented for the first time, revealing the potential for applications in biological systems. The temperature-sensing capability...
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Nutrients, Vol. 12, Pages 301: The Effects of Gelatinized Wheat Starch and High Salt Diet on Gut Microbiota and Metabolic Disorder Nutrients doi: 10.3390/nu12020301 Authors: Moon Ho Do Hye-Bin Lee Eunjung Lee Ho-Young Park Diets high in gelatinized starch and high in gelatinized starch supplemented with salt-induced metabolic disorders and changes in gut microbiota have scarcely been studied. In this study, mice on wheat starch diets (WD) exhibited significantly higher body...
Nutrients, Vol. 12, Pages 299: Health Benefits of Whey or Colostrum Supplementation in Adults ≥35 Years; a Systematic Review Nutrients doi: 10.3390/nu12020299 Authors: Blair Kellow Dordevic Evans Caissutti McCaffrey Food-health claims are an important method of translating nutrition research to consumers. Whey and colostrum are thought to exert health benefits to adults, but it is unclear what measurable, objective health benefits they impart. This review aimed to...
Nutrients, Vol. 12, Pages 298: Effects of Extrinsic Wheat Fiber Supplementation on Fecal Weight; A Randomized Controlled Trial Nutrients doi: 10.3390/nu12020298 Authors: Brandl Lee Dunkel Hofmann Hauner Skurk Higher fiber intake may confer beneficial effects on health. Our objective was to investigate the impact of 10 g extrinsic wheat fiber on fecal bulk. Therefore, we performed two randomized intervention studies in which we provided extrinsic wheat fiber-enriched...
Nutrients, Vol. 12, Pages 297: Expression Patterns of Muscle-Specific miR-133b and miR-206 Correlate with Nutritional Status and Sarcopenia Nutrients doi: 10.3390/nu12020297 Authors: Iannone Montesanto Cione Crocco Caroleo Dato Rose Passarino Sarcopenia and malnutrition are commonly occurring conditions in the elderly that frequently coexist, leading to substantial effects on morbidity/mortality. Evidence established muscle-specific microRNAs (miRNAs) or...
Nutrients, Vol. 12, Pages 300: Wheat Extract Oil (WEO) Attenuates UVB-Induced Photoaging via Collagen Synthesis in Human Keratinocytes and Hairless Mice Nutrients doi: 10.3390/nu12020300 Authors: Son Jung Choi Ryu Lee Davis The efficacy of wheat extract oil (WEO), standardized to glucosylceramides, for protecting against ultraviolet B (UVB)-induced damage of skin barrier function was assessed using the SHK-1 hairless mouse model and two human skin cell lines, namely,...
Nutrients, Vol. 12, Pages 294: The Effect of a Food Addiction Explanation Model for Weight Control and Obesity on Weight Stigma Nutrients doi: 10.3390/nu12020294 Authors: O’Brien Puhl Latner Lynott Reid Vakhitova Hunter Scarf Jeanes Bouguettaya Carter There is increasing scientific and public support for the notion that some foods may be addictive, and that poor weight control and obesity may, for some people, stem from having a food addiction....
Nutrients, Vol. 12, Pages 295: Starch Digestion Enhances Bioaccessibility of Anti-Inflammatory Polyphenols from Borlotti Beans (Phaseolus vulgaris) Nutrients doi: 10.3390/nu12020295 Authors: Perez-Hernandez Nugraheni Benohoud Sun Hernández-Álvarez Morgan Boesch Orfila The consumption of beans has been associated with chronic disease prevention which may be attributed to the polyphenols present in the seed coat and endosperm. However, their bioaccessibility...
Nutrients, Vol. 12, Pages 293: Selected Predictors of the Importance Attached to Salt Content Information on the Food Packaging (a Study among Polish Consumers) Nutrients doi: 10.3390/nu12020293 Authors: Bryła This paper aims to identify selected antecedents of the importance attached to salt content information (ISCI) placed on food labels, on the basis of a representative survey of 1051 Polish consumers. The study was conducted with the use of the CAWI (Computer Assisted Web Interviews)...
Nutrients, Vol. 12, Pages 296: Effect of Maternal Obesity in Mice on IL-6 Levels and Placental Endothelial Cell Homeostasis Nutrients doi: 10.3390/nu12020296 Authors: Kretschmer Schulze-Edinghausen Turnwald Janoschek Bae-Gartz Zentis Handwerk Wohlfarth Schauss Hucklenbruch-Rother Dötsch Appel Obesity during pregnancy is a known health risk for mother and child. Since obesity is associated with increased inflammatory markers, our objectives...
Nutrients, Vol. 12, Pages 291: Low Levels of Vitamin D Promote Memory B Cells in Lupus Nutrients doi: 10.3390/nu12020291 Authors: Yamamoto Nguyen Liu Keller Campbell Zhang Smith Li Jørgensen Background: Vitamin D deficiency is a known risk factor for Systemic Lupus Erythematosus (SLE), yet clinical trials have not demonstrated efficacy and few studies have utilized lupus models to understand the mechanism underlying this relationship. The Act1-/- mouse...
Nutrients, Vol. 12, Pages 292: The Emerging Role of Vitamin C as a Treatment for Sepsis Nutrients doi: 10.3390/nu12020292 Authors: Kashiouris L’Heureux Cable Fisher Leichtle III Sepsis, a life-threatening organ dysfunction due to a dysregulated host response to infection, is a leading cause of morbidity and mortality worldwide. Decades of research have failed to identify any specific therapeutic targets outside of antibiotics, infectious source elimination, and supportive...
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Pathogens, Vol. 9, Pages 76: Estimating the Clinical and Economic Impact of Switching from the 13-Valent Pneumococcal Conjugate Vaccine (PCV13) to the 10-Valent Pneumococcal Conjugate Vaccine (PCV10) in Italy Pathogens doi: 10.3390/pathogens9020076 Authors: Ansaldi Pugh Amicizia Di Virgilio Trucchi Orsi Zollo Icardi Background: Invasive and non-invasive pneumococcal diseases are significant health and economic burdens, especially in children and the elderly....
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Pharmaceuticals, Vol. 13, Pages 20: Structure–Activity Relationships (SARs) of α-Ketothioamides as Inhibitors of Phosphoglycerate Dehydrogenase (PHGDH) Pharmaceuticals doi: 10.3390/ph13020020 Authors: Spillier Ravez Unterlass Corbet Degavre Feron Frédérick For many years now, targeting deregulation within cancer cells’ metabolism has appeared as a promising strategy for the development of more specific and efficient cancer treatments. Recently, numerous...
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Pharmaceutics, Vol. 12, Pages 91: Treating Intracranial Abscesses in Rats with Stereotactic Injection of Biodegradable Vancomycin-Embedded Microparticles Pharmaceutics doi: 10.3390/pharmaceutics12020091 Authors: Tseng Kao Liu Tang Liu Liu Brain abscesses are emergent and life-threating despite advances in modern neurosurgical techniques and antibiotics. The present study explores the efficacy of vancomycin embedded to 50:50 poly(lactic-co-glycolide acid) (PLGA) microparticles...
Pharmaceutics, Vol. 12, Pages 90: Solubility, Antioxidation, and Oral Bioavailability Improvement of Mangiferin Microparticles Prepared Using the Supercritical Antisolvent Method Pharmaceutics doi: 10.3390/pharmaceutics12020090 Authors: Liu Liu Ge Zhong Wang Wu Zhao Zu In view of the poor water solubility and low oral bioavailability of mangiferin (MG), in this study, the supercritical antisolvent (SAS) technology was used to prepare mangiferin microparticles...
Pharmaceutics, Vol. 12, Pages 89: Design of New Polyaspartamide Copolymers for siRNA Delivery in Antiasthmatic Therapy Pharmaceutics doi: 10.3390/pharmaceutics12020089 Authors: Craparo Drago Mauro Giammona Cavallaro Here, a novel protonable copolymer was realized for the production of polyplexes with a siRNA (inhibitor of STAT6 expression in asthma), with the aim of a pulmonary administration. The polycation was synthesized by derivatization of α,β-poly(N-2-hydroxyethyl)d,l-aspartamide...
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Plants, Vol. 9, Pages 142: Phenolic Profile, Toxicity, Enzyme Inhibition, In Silico Studies, and Antioxidant Properties of Cakile maritima Scop. (Brassicaceae) from Southern Portugal Plants doi: 10.3390/plants9020142 Authors: Placines Castañeda-Loaiza João Rodrigues Pereira Stefanucci Mollica Zengin Llorent-Martínez Castilho Custódio Cakile maritima Scop. (sea rocket) is an edible halophyte plant with several ethnomedicinal uses. This work reports...
Plants, Vol. 9, Pages 141: Invasive Mesquite (Prosopis juliflora), an Allergy and Health Challenge Plants doi: 10.3390/plants9020141 Authors: Hussain Shackleton El-Keblawy Del Mar Trigo Pérez González Mesquite (Prosopis juliflora (Sw.) DC), is an medium-sized tree (family Fabaceae, subfamily Mimosoideae), that has been intorcuded around the world. It is a noxious invasive species in Africa, Asia, and the Arabian Peninsula and a source of highly allergenic pollen in....
Plants, Vol. 9, Pages 143: The Phytochemical Composition of Melia volkensii and Its Potential for Insect Pest Management Plants doi: 10.3390/plants9020143 Authors: Jaoko Nji Tizi Taning Backx Mulatya Van den Abeele Magomere Olubayo Mangelinckx Werbrouck Smagghe Due to potential health and environmental risks of synthetic pesticides, coupled with their non-selectivity and pest resistance, there has been increasing demand for safer and biodegradable...
Plants, Vol. 9, Pages 140: Low phytic acid Crops: Observations Based On Four Decades of Research Plants doi: 10.3390/plants9020140 Authors: Raboy The low phytic acid (lpa), or “low-phytate” seed trait can provide numerous potential benefits to the nutritional quality of foods and feeds and to the sustainability of agricultural production. Major benefits include enhanced phosphorus (P) management contributing to enhanced sustainability in non-ruminant (poultry, swine,...
Plants, Vol. 9, Pages 139: Gibberellins and Heterosis in Crops and Trees: An Integrative Review and Preliminary Study with Brassica Plants doi: 10.3390/plants9020139 Authors: Zanewich Rood Heterosis, or hybrid vigor, has contributed substantially to genetic improvements in crops and trees and its physiological basis involves multiple processes. Four associations with the phytohormone gibberellin (GA) indicate its involvement in the regulation of heterosis for shoot growth in maize,...
Plants, Vol. 9, Pages 137: Amaryllidaceae Alkaloids of Different Structural Types from Narcissus L. cv. Professor Einstein and Their Cytotoxic Activity Plants doi: 10.3390/plants9020137 Authors: Breiterová Koutová Maříková Havelek Kuneš Majorošová Opletal Hošťálková Jenčo Řezáčová Cahlíková In this detailed phytochemical study of Narcissus cv. Professor Einstein, we isolated 23 previously known Amaryllidaceae alkaloids (1–23) of several...
Plants, Vol. 9, Pages 138: Genetic Variance Estimates for Maize Yield, Grain Moisture, and Stalk Lodging for Doubled-Haploid and Conventional Selfed-Line Hybrids Plants doi: 10.3390/plants9020138 Authors: Mowers Foster An experiment was conducted to compare estimated genetic variance for maize doubled haploid (DH) with conventional twice-selfed (S2)-line hybrids. Starting with a 4-parent population, at least 160 lines were derived using both of these methods and crossed with two...
Plants, Vol. 9, Pages 136: Role of Jasmonic Acid Pathway in Tomato Plant-Pseudomonas syringae Interaction Plants doi: 10.3390/plants9020136 Authors: Scalschi Llorens García-Agustín Vicedo The jasmonic acid pathway has been considered as the backbone of the response against necrotrophic pathogens. However, a hemi-biotrophic pathogen, such as Pseudomonas syringae, has taken advantage of the crosstalk between the different plant hormones in order to manipulate the responses...
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Proteomes, Vol. 8, Pages 2: Acknowledgement to Reviewers of Proteomes in 2019 Proteomes doi: 10.3390/proteomes8010002 Authors: Proteomes Editorial Office The editorial team greatly appreciates the reviewers who have dedicated their considerable time and expertise to the journal’s rigorous editorial process over the past 12 months, regardless of whether the papers are finally published or not [...]
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Religions, Vol. 11, Pages 57: Validation of the Short Forms of the Centrality of Religiosity Scale in Georgia Religions doi: 10.3390/rel11020057 Authors: Ackert Maglakelidze Badurashvili Huber This study presents the validation of the short forms of Centrality of Religiosity Scale (CRS) in Georgia. This country offers a unique Christian orthodox context with a long-lasting religious tradition and strong affiliation to churches. Translated short forms were administered in...
Religions, Vol. 11, Pages 58: Facing the Monsters: Otherness in H. P. Lovecraft’s Cthulhu Mythos and Guillermo del Toro’s Pacific Rim and Hellboy Religions doi: 10.3390/rel11020058 Authors: McConeghy What happens when we imagine the unimaginable? This article compares recent films inspired by H. P. Lovecraft’s Cthulhu Mythos with that author’s original early 20th century pulp horror stories. In Guillermo del Toro’s films Pacific Rim and Hellboy, monsters...
Religions, Vol. 11, Pages 56: Ted Chiang’s Asian American Amusement at Alien Arrival Religions doi: 10.3390/rel11020056 Authors: Esaki In the 2016 movie Arrival, aliens with advanced technology appear on Earth in spaceships reminiscent of the black obelisk in 2001: A Space Odyssey. The film presents this arrival as a serious problem to be solved, with the future of human life and interplanetary relationships in the balance. The short story, “Story of Your Life” by...
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Resources, Vol. 9, Pages 11: Applications of Geophysical Logs to Coal Mining—Some Illustrative Examples Resources doi: 10.3390/resources9020011 Authors: Zhou Guo Geophysical logs can be used not only for qualitative interpretation such as strata correlation but also for geotechnical assessment through quantitative data analysis. In an emerging digital mining age, such a use of geophysical logs helps to establish reliable geological and geotechnical models, which reduces safety and...
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Societies, Vol. 10, Pages 12: Acknowledgement to Reviewers of Societies in 2019 Societies doi: 10.3390/soc10010012 Authors: Societies Editorial Office Rigorous peer-review is the corner-stone of high-quality academic publishing. The editorial teamgreatly appreciates the reviewers who contributed their knowledge and expertise to the journal’seditorial process over the past 12 months. [...]
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Sports, Vol. 8, Pages 13: The Effect of ProHydrolase® on the Amino Acid and Intramuscular Anabolic Signaling Response to Resistance Exercise in Trained Males Sports doi: 10.3390/sports8020013 Authors: Townsend Morimune Jones Beuning Haase Boot Heffington Littlefield Henry Marshall VanDusseldorp Feito Mangine This double-blind study examined effects of a protease enzyme blend (Prohydrolase®) added to whey protein on post-resistance...
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Toxics, Vol. 8, Pages 7: Monosodium Glutamate (MSG)-Induced Male Reproductive Dysfunction: A Mini Review Toxics doi: 10.3390/toxics8010007 Authors: Kayode Rotimi Kayode Olaolu Adeyemi Reproductive dysfunction is often characterized by malfunction of the reproductive tissues, which may lead to disruption of the synergistic rhythm that should bring about a progression of sexual events and the conception of new life. This may therefore result in the sexual dysfunction and...
Toxics, Vol. 8, Pages 6: Dietary Pyrethroid Exposures and Intake Doses for 188 Duplicate-Single Solid Food Items Consumed by North Carolina Adults Toxics doi: 10.3390/toxics8010006 Authors: Morgan Few studies have measured pyrethroid residue concentrations in food items consumed by adults in their daily environments. In a further analysis of study data, the objectives were to determine pyrethroid residue levels in single, solid food items consumed by adults and to estimate dietary pyrethroid...
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Toxins, Vol. 12, Pages 70: Ostreopsis cf. ovata (Dinophyceae) Molecular Phylogeny, Morphology, and Detection of Ovatoxins in Strains and Field Samples from Brazil Toxins doi: 10.3390/toxins12020070 Authors: Nascimento Neves De’Carli Borsato Silva Melo Morais Cockell Fraga Menezes-Salgueiro Mafra Hess Salgueiro : Recurrent blooms of Ostreopsis cf. ovata have been reported in Brazil and the Mediterranean Sea with associated ecological, and...
Toxins, Vol. 12, Pages 69: Modeling of Effective Antimicrobials to Reduce Staphylococcus aureus Virulence Gene Expression Using a Two-Compartment Hollow Fiber Infection Model Toxins doi: 10.3390/toxins12020069 Authors: Shukla Carter Ye Pantrangi Rose Toxins produced by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) contribute to virulence. We developed a statistical approach to determine an optimum sequence of antimicrobials to treat CA-MRSA...
Toxins, Vol. 12, Pages 68: Amplification of Snake Venom Toxicity by Endogenous Signaling Pathways Toxins doi: 10.3390/toxins12020068 Authors: Bickler The active components of snake venoms encompass a complex and variable mixture of proteins that produce a diverse, but largely stereotypical, range of pharmacologic effects and toxicities. Venom protein diversity and host susceptibilities determine the relative contributions of five main pathologies: neuromuscular dysfunction, inflammation,...
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Vaccines, Vol. 8, Pages 39: Humanized Mice in Dengue Research: A Comparison with Other Mouse Models Vaccines doi: 10.3390/vaccines8010039 Authors: Coronel-Ruiz Gutiérrez-Barbosa Medina-Moreno Velandia-Romero Chua Castellanos Zapata Dengue virus (DENV) is an arbovirus of the Flaviviridae family and is an enveloped virion containing a positive sense single-stranded RNA genome. DENV causes dengue fever (DF) which is characterized by an undifferentiated syndrome...
Vaccines, Vol. 8, Pages 38: Being Pregnant during the Kivu Ebola Virus Outbreak in DR Congo: The rVSV-ZEBOV Vaccine and Its Accessibility by Mothers and Infants during Humanitarian Crises and in Conflict Areas Vaccines doi: 10.3390/vaccines8010038 Authors: Schwartz The Ebola virus disease (EVD) outbreak that began in Kivu province of the Democratic Republic of the Congo (DRC) in July 2018 is the second largest in history. It is also the largest and most deadly of the ten Ebola outbreaks...
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Viruses, Vol. 12, Pages 131: TRIM41-Mediated Ubiquitination of Nucleoprotein Limits Vesicular Stomatitis Virus Infection Viruses doi: 10.3390/v12020131 Authors: Patil Xu Wu Song Hao Hua Wang Li Vesicular stomatitis virus (VSV) is a zoonotic, negative-stranded RNA virus of the family Rhabdoviridae. The nucleoprotein (N) of VSV protects the viral genomic RNA and plays an essential role in viral transcription and replication, which makes the nucleoprotein an...
Viruses, Vol. 12, Pages 130: Emerging Viruses without Borders: The Wuhan Coronavirus Viruses doi: 10.3390/v12020130 Authors: Liu Saif The recently emerged coronavirus in Wuhan, China has claimed at least two lives as of January 17 and infected hundreds if not thousands of individuals. The situation has drawn international attention, including from the virology community. We applaud the rapid release to the public of the genome sequence of the new virus by Chinese virologists, but...
Viruses, Vol. 12, Pages 129: Defenses against Virus and Vector: A Phloem-Biological Perspective on RTM- and SLI1-Mediated Resistance to Potyviruses and Aphids Viruses doi: 10.3390/v12020129 Authors: Kloth Kormelink Combining plant resistance against virus and vector presents an attractive approach to reduce virus transmission and virus proliferation in crops. Restricted Tobacco-etch virus Movement (RTM) genes confer resistance to potyviruses by limiting their long-distance transport....
Viruses, Vol. 12, Pages 132: The Potyviruses: An Evolutionary Synthesis Is Emerging Viruses doi: 10.3390/v12020132 Authors: Gibbs Hajizadeh Ohshima Jones In this review, encouraged by the dictum of Theodosius Dobzhansky that “Nothing in biology makes sense except in the light of evolution”, we outline the likely evolutionary pathways that have resulted in the observed similarities and differences of the extant molecules, biology, distribution, etc. of...
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Water, Vol. 12, Pages 323: Measurement and Modelling of Moisture Sorption Isotherm and Heat of Sorption of Fresh Feces Water doi: 10.3390/w12020323 Authors: Remington Bourgault Dorea The drying (or dewatering) of fresh feces and fecal sludge is a productive step in the management of sanitation, waste treatment, and resource recovery services. An improved understanding of fresh feces and fecal sludge drying would contribute to the development and deployment of fecal sludge management...
Water, Vol. 12, Pages 324: Particle Dynamics in Ushuaia Bay (Tierra del Fuego)-Potential Effect on Dissolved Oxygen Depletion Water doi: 10.3390/w12020324 Authors: Melo Martín Kerdel Bourrin Colloca Menniti de Madron This study examines the distribution and seasonal evolution of hydrographic, hydrodynamic, and nepheloid layers in Ushuaia Bay and the submerged glacial valley that connects it to the Beagle Channel. The hydrographic structure is highly seasonal,...
Water, Vol. 12, Pages 322: Hydrochemical Conditions for Aerobic/Anaerobic Biodegradation of Chlorinated Ethenes—A Multi-Site Assessment Water doi: 10.3390/w12020322 Authors: Němeček Marková Špánek Antoš Kozubek Lhotský Černík A stall of cis-1,2-DCE and vinyl chloride (VC) is frequently observed during bioremediation of groundwater chloroethenes via reductive dechlorination. These chloroethenes may be oxidised by aerobic methanotrophs or ethenotrophs co-metabolically...
Water, Vol. 12, Pages 325: Syrian Refugees, Water Scarcity, and Dynamic Policies: How Do the New Refugee Discourses Impact Water Governance Debates in Lebanon and Jordan? Water doi: 10.3390/w12020325 Authors: Hussein Natta Yehya Hamadna Since the Syrian crisis and the so-called “Arab Spring”, new discourses have been created, sparking the discursive water governance debates around water scarcity and hydropolitics. In Lebanon and Jordan—where...
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