Skin Microbiome Compositional Changes in Atopic Dermatitis Accompany Dead Sea Climatotherapy

Michael Brandwein, Garold Fuks, Avigail Israel, Fareed Sabbah, Emmilia Hodak, Amir Szitenberg, Marco Harari, Droron Steinberg, Zvi Bentwich, Noam Shental, Shiri Meshner

Version of Record online: 10 July 2019

 

Microbiome dysbiosis is a hallmark of atopic dermatitis and has been shown to be change following several different treatment modalities. Dead Sea climatotherapy is a well‐established therapeutic modality for the treatment of atopic dermatitis, yet its effect on the skin microbiome of AD patients has not yet been explored. Brandwein et al. show that Dead Sea climatotherapy induces changes in the skin microbiome, yet surprisingly does not significantly reduce the relative abundance of Staphylococcus aureus. These observations shed light on the unique nature of Dead Sea climatotherapy, and its ability to provide relief for a number of different disease states.