- Cerebral Hyperperfusion Syndrome After Chronic Subdural Hematoma Drainage.Related ArticlesCerebral Hyperperfusion Syndrome After Chronic Subdural Hematoma Drainage. World Neurosurg. 2019 Jun;126:694 Authors: Sharma P, Rege SV PMID: 31546329 [PubMed - in process]
- In Reply to the Letter to the Editor Regarding "Factors Influencing Medical Student Interest in a Career in Neurosurgery".Related ArticlesIn Reply to the Letter to the Editor Regarding "Factors Influencing Medical Student Interest in a Career in Neurosurgery". World Neurosurg. 2019 Jun;126:693 Authors: Burford C, Hanrahan J, Ansaripour A, Smith B, Sysum K, Rajwani K, Huett M, Vergani F, Zebian B PMID: 31546328 [PubMed - in process]
- Letter to the Editor Regarding "Factors Influencing Medical Student Interest in a Career in Neurosurgery".Related ArticlesLetter to the Editor Regarding "Factors Influencing Medical Student Interest in a Career in Neurosurgery". World Neurosurg. 2019 Jun;126:692 Authors: Zheng S, Cheng Y PMID: 31546327 [PubMed - in process]
- In Reply to the Letter to the Editor Regarding "Hypnosis-Aided Awake Surgery for the Management of Intrinsic Brain Tumors versus Standard Awake-Asleep-Awake Protocol: A Preliminary, Promising Experience".Related ArticlesIn Reply to the Letter to the Editor Regarding "Hypnosis-Aided Awake Surgery for the Management of Intrinsic Brain Tumors versus Standard Awake-Asleep-Awake Protocol: A Preliminary, Promising Experience". World Neurosurg. 2019 Jun;126:690-691 Authors: Frati A, Pesce A, Palmieri M, Iasanzaniro M, Familiari P, Angelini A, Salvati M, Rossi I, Raco A PMID: 31546326 [PubMed - in process]
- In Reply to the "Letter to the Editor Regarding Intraneural Ewing Sarcoma of the Fibular Nerve-Case Report, Radiologic Findings and Review of Literature".Related ArticlesIn Reply to the "Letter to the Editor Regarding Intraneural Ewing Sarcoma of the Fibular Nerve-Case Report, Radiologic Findings and Review of Literature". World Neurosurg. 2019 Jun;126:687 Authors: Lavorato A, Titolo P, Vincitorio F, Cofano F, Garbossa D PMID: 31546325 [PubMed - in process]
- Letter to the Editor Regarding "Percutaneous Endoscopic Laminotomy with Flavectomy by Uniportal, Unilateral Approach for the Lumbar Canal or Lateral Recess Stenosis".Related ArticlesLetter to the Editor Regarding "Percutaneous Endoscopic Laminotomy with Flavectomy by Uniportal, Unilateral Approach for the Lumbar Canal or Lateral Recess Stenosis". World Neurosurg. 2019 Jun;126:686 Authors: Jia ZQ, Rong XQ, Diao WB, Zhao LT, Yan M, He XJ PMID: 31546324 [PubMed - in process]
- Letter to the Editor Regarding "A Retrospective Cohort Analysis of Hemorrhagic Arteriovenous Malformations Treated with Combined Endovascular Embolization and Gamma Knife Stereotactic Radiosurgery".Related ArticlesLetter to the Editor Regarding "A Retrospective Cohort Analysis of Hemorrhagic Arteriovenous Malformations Treated with Combined Endovascular Embolization and Gamma Knife Stereotactic Radiosurgery". World Neurosurg. 2019 Jun;126:683-684 Authors: Zhang L, Chen W, Hu Y, Chen J PMID: 31546323 [PubMed - in process]
- Letter to the Editor Regarding "Did Ibn Zuhr (Avenzoar) Postulate Before Vesalius That Liquid Collects in Ventricles in the Hydrocephalus?"Related ArticlesLetter to the Editor Regarding "Did Ibn Zuhr (Avenzoar) Postulate Before Vesalius That Liquid Collects in Ventricles in the Hydrocephalus?" World Neurosurg. 2019 Jun;126:681-682 Authors: Missori P, Paolini S, Peschillo S, Currà A PMID: 31546322 [PubMed - in process]
- Dural Repair Technique in Decompressive Craniotomy: Benefits During Cranioplasty.Related ArticlesDural Repair Technique in Decompressive Craniotomy: Benefits During Cranioplasty. World Neurosurg. 2019 Jun;126:680 Authors: Farias SA, Machado-Filho WS, Amorim RL, Paiva WS PMID: 31546321 [PubMed - in process]
- Coanda Effect-Another Entity in "Vasospasm Mimics" Lists.Related ArticlesCoanda Effect-Another Entity in "Vasospasm Mimics" Lists. World Neurosurg. 2019 Jun;126:679 Authors: Munakomi S PMID: 31546320 [PubMed - in process]
- Artificial Intelligence in Clinical Neurosciences.Related ArticlesArtificial Intelligence in Clinical Neurosciences. World Neurosurg. 2019 Jun;126:611-612 Authors: Oermann EK, Gologorsky Y PMID: 31546319 [PubMed - in process]
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pubmed: frontiers in neurosc...
- Impact of Temporomandibular Joint Complaints on Tinnitus-Related Distress.Related ArticlesImpact of Temporomandibular Joint Complaints on Tinnitus-Related Distress. Front Neurosci. 2019;13:879 Authors: Edvall NK, Gunan E, Genitsaridi E, Lazar A, Mehraei G, Billing M, Tullberg M, Bulla J, Whitton J, Canlon B, Hall DA, Cederroth CR Abstract There is increasing evidence of associations between the presence of temporomandibular joint (TMJ) disorders and tinnitus. It has been r
Molecular Carcinogenesis
- Primary tumor‐secreted VEGF induces vascular hyperpermeability in premetastatic lung via the occludin phosphorylation/ubiquitination pathwayAbstract Primary tumor can induce the formation of premetastatic niche. The hyperpermeability of the vessels in the premetastatic niche is the first step in the development of metastasis. However, the cellular and molecular mechanisms of vascular hyperpermeability remain to be elucidated. In this study, 4T1 breast cells were injected into the breasts of mice to establish a tumor model. Our results showed that primary tumors induced hyperpermeabi
- CpG Oligodeoxynucleotide Promotes Apoptosis of Human Bladder Cancer T24 Cells Via Inhibition of the Antiapoptotic Factors.Related ArticlesCpG Oligodeoxynucleotide Promotes Apoptosis of Human Bladder Cancer T24 Cells Via Inhibition of the Antiapoptotic Factors. Technol Cancer Res Treat. 2019 Jan 01;18:1533033819873636 Authors: Luo Y, Dong Y, Liang S, Yuan L, Men H, Zhang S, Tian S, Fu X, Dong B, Meng M Abstract OBJECTIVE: Unmethylated cytosine-phosphorothioate-guanine oligodeoxynucleotide, a synthetic oligodeoxynucleotid
- The Mycotoxin Deoxynivalenol Significantly Alters the Function and Metabolism of Bovine Kidney Epithelial Cells In Vitro.Related ArticlesThe Mycotoxin Deoxynivalenol Significantly Alters the Function and Metabolism of Bovine Kidney Epithelial Cells In Vitro. Toxins (Basel). 2019 Sep 20;11(10): Authors: Bailey JR, Breton J, Panic G, Cogan TA, Bailey M, Swann JR, Lee MRF Abstract Bovine mycotoxicosis is a disorder caused by the ingestion of fungal toxins. It is associated with chronic signs, such as reduced growth rate a
- HtrA4 Protease Promotes Chemotherapeutic-Dependent Cancer Cell Death.Related ArticlesHtrA4 Protease Promotes Chemotherapeutic-Dependent Cancer Cell Death. Cells. 2019 Sep 20;8(10): Authors: Wenta T, Rychlowski M, Jarzab M, Lipinska B Abstract The HtrA4 human protease is crucial in placentation and embryo implantation, and its altered level is connected with pre-eclampsia. The meta-analyses of microarray assays revealed that the HtrA4 level is changed in brain tumors a
- Proteomic Analysis of miR-195 and miR-497 Replacement Reveals Potential Candidates that Increase Sensitivity to Oxaliplatin in MSI/P53wt Colorectal Cancer Cells.Related ArticlesProteomic Analysis of miR-195 and miR-497 Replacement Reveals Potential Candidates that Increase Sensitivity to Oxaliplatin in MSI/P53wt Colorectal Cancer Cells. Cells. 2019 Sep 19;8(9): Authors: Poel D, Boyd LNC, Beekhof R, Schelfhorst T, Pham TV, Piersma SR, Knol JC, Jimenez CR, Verheul HMW, Buffart TE Abstract Most patients with advanced colorectal cancer (CRC) eventually develop r
- Corilagin in Cancer: A Critical Evaluation of Anticancer Activities and Molecular Mechanisms.Related ArticlesCorilagin in Cancer: A Critical Evaluation of Anticancer Activities and Molecular Mechanisms. Molecules. 2019 Sep 19;24(18): Authors: Gupta A, Singh AK, Kumar R, Ganguly R, Rana HK, Pandey PK, Sethi G, Bishayee A, Pandey AK Abstract Corilagin (β-1-O-galloyl-3,6-(R)-hexahydroxydiphenoyl-d-glucose), an ellagitannin, is one of the major bioactive compounds present in various plants. Ella
- A survey of Canadian breast health professionals’ recommendations for high-risk benign breast diseaseA survey of Canadian breast health professionals’ recommendations for high-risk benign breast disease Can J Surg. 2019 Oct 01;62(5):358-360 Authors: Kappel C, Seely J, Watters J, Arnaout A, Cordeiro E Abstract Summary: The management of high-risk benign breast disease (BBD) is changing because of improvements in radiological and pathological analysis. We sought to determine the current practice recom
- Low-dose-rate brachytherapy for prostate cancer: A 15-year experience in Japan.Low-dose-rate brachytherapy for prostate cancer: A 15-year experience in Japan. Int J Urol. 2019 Sep 24;: Authors: Tanaka N, Asakawa I, Hasegawa M, Fujimoto K Abstract The history of prostate brachytherapy has passed one century. In 1983, modern low-dose-rate prostate brachytherapy using a transrectal ultrasound-guided procedure was introduced. In the early 1990s, low-dose-rate brachytherapy was intr
- The BRCA2 mutation status shapes the immune phenotype of prostate cancer.Related ArticlesThe BRCA2 mutation status shapes the immune phenotype of prostate cancer. Cancer Immunol Immunother. 2019 Sep 23;: Authors: Jenzer M, Keß P, Nientiedt C, Endris V, Kippenberger M, Leichsenring J, Stögbauer F, Haimes J, Mishkin S, Kudlow B, Kaczorowski A, Zschäbitz S, Volckmar AL, Sültmann H, Jäger D, Duensing A, Schirmacher P, Hohenfellner M, Grüllich C, Stenzinger A, Duensing S Abstract
- Cognitive and brain structural changes in long-term oligodendroglial tumor survivors.Related ArticlesCognitive and brain structural changes in long-term oligodendroglial tumor survivors. Neuro Oncol. 2019 Aug 09;: Authors: Cayuela N, Jaramillo-Jiménez E, Càmara E, Majós C, Vidal N, Lucas A, Gil-Gil M, Graus F, Bruna J, Simó M Abstract BACKGROUND: We identify cognitive impairment and MRI structural brain changes in long-term oligodendroglial tumor survivors treated with radiation ther
- Crizotinib inhibition of ROS1-positive tumours in advanced non-small-cell lung cancer: a Canadian perspective.Related ArticlesCrizotinib inhibition of ROS1-positive tumours in advanced non-small-cell lung cancer: a Canadian perspective. Curr Oncol. 2019 Aug;26(4):e551-e557 Authors: Bebb DG, Agulnik J, Albadine R, Banerji S, Bigras G, Butts C, Couture C, Cutz JC, Desmeules P, Ionescu DN, Leighl NB, Melosky B, Morzycki W, Rashid-Kolvear F, Lab C, Sekhon HS, Smith AC, Stockley TL, Torlakovic E, Xu Z, Tsao MS Abstract
- An evaluation of the safety of continuing trastuzumab despite overt left ventricular dysfunction.Related ArticlesAn evaluation of the safety of continuing trastuzumab despite overt left ventricular dysfunction. Curr Oncol. 2019 Aug;26(4):240-246 Authors: Barron CC, Alhussein MM, Kaur U, Cosman TL, Tyagi NK, Brown M, Mukherjee SD, Ellis PM, Dhesy-Thind S, Leong DP Abstract Background: The major limitation in the use of trastuzumab therapy is cardiotoxicity. We evaluated the safety of a strategy o
- Mutation profiling of cancer drivers in Brazilian colorectal cancer.Related ArticlesMutation profiling of cancer drivers in Brazilian colorectal cancer. Sci Rep. 2019 Sep 23;9(1):13687 Authors: Dos Santos W, Sobanski T, de Carvalho AC, Evangelista AF, Matsushita M, Berardinelli GN, de Oliveira MA, Reis RM, Guimarães DP Abstract The molecular basis of colorectal cancer (CRC) can guide patient prognosis and therapy. In Brazil, knowledge on the CRC mutation landscape is
- Breast cancer.Related ArticlesBreast cancer. Nat Rev Dis Primers. 2019 Sep 23;5(1):66 Authors: Harbeck N, Penault-Llorca F, Cortes J, Gnant M, Houssami N, Poortmans P, Ruddy K, Tsang J, Cardoso F Abstract Breast cancer is the most frequent malignancy in women worldwide and is curable in ~70-80% of patients with early-stage, non-metastatic disease. Advanced breast cancer with distant organ metastases is considered
- Ovarian Follicle Depletion Induced by Chemotherapy and the Investigational Stages of Potential Fertility-Protective Treatments-A Review.Related ArticlesOvarian Follicle Depletion Induced by Chemotherapy and the Investigational Stages of Potential Fertility-Protective Treatments-A Review. Int J Mol Sci. 2019 Sep 23;20(19): Authors: Hao X, Anastácio A, Liu K, Rodriguez-Wallberg KA Abstract Ovarian follicle pool depletion, infertility, and premature menopause are all known sequelae of cancer treatment that negatively impact the quality
- Cancer Genetic Counseling-Current Practice and Future Challenges.Related ArticlesCancer Genetic Counseling-Current Practice and Future Challenges. Cold Spring Harb Perspect Med. 2019 Sep 23;: Authors: Schienda J, Stopfer J Abstract Cancer genetic counseling practice is rapidly evolving, with services being provided in increasingly novel ways. Pretest counseling for cancer patients may be abbreviated from traditional models to cover the elements of informed consent
- Brain Metastasis Organotropism.Related ArticlesBrain Metastasis Organotropism. Cold Spring Harb Perspect Med. 2019 Sep 23;: Authors: Yuzhalin AE, Yu D Abstract Brain metastases are associated with poor prognosis irrespective of the primary tumor they originate from. Current treatments for brain metastases are palliative, and patients with symptomatic brain metastasis have a one-year survival of <20%. Lung cancer, breast cancer, an
- Current Treatment Options for Metastatic Hormone-Sensitive Prostate Cancer.Related ArticlesCurrent Treatment Options for Metastatic Hormone-Sensitive Prostate Cancer. Cancers (Basel). 2019 Sep 12;11(9): Authors: Cattrini C, Castro E, Lozano R, Zanardi E, Rubagotti A, Boccardo F, Olmos D Abstract The possible treatments options for metastatic hormone-sensitive prostate cancer (mHSPC) have dramatically increased during the last years. The old backbone, which androgen-deprivat
- Perspective: Cellular and Molecular Profiling Technologies in Personalized Oncology.Related ArticlesPerspective: Cellular and Molecular Profiling Technologies in Personalized Oncology. J Pers Med. 2019 Sep 12;9(3): Authors: Cruz A, Peng WK Abstract Cancer is a leading cause of death worldwide and therefore one of the most important public health concerns. In this contribution, we discuss recent key enabling technological innovations (and their challenges), including biomarker-based
- Prognostic and Predictive Implications of PTEN in Breast Cancer: Unfulfilled Promises but Intriguing Perspectives.Related ArticlesPrognostic and Predictive Implications of PTEN in Breast Cancer: Unfulfilled Promises but Intriguing Perspectives. Cancers (Basel). 2019 Sep 19;11(9): Authors: Carbognin L, Miglietta F, Paris I, Dieci MV Abstract The characterization of tumor biology and consequently the identification of prognostic and predictive biomarkers represent key issues for the translational research in breas
- Matched Whole-Genome Sequencing (WGS) and Whole-Exome Sequencing (WES) of Tumor Tissue with Circulating Tumor DNA (ctDNA) Analysis: Complementary Modalities in Clinical Practice.Related ArticlesMatched Whole-Genome Sequencing (WGS) and Whole-Exome Sequencing (WES) of Tumor Tissue with Circulating Tumor DNA (ctDNA) Analysis: Complementary Modalities in Clinical Practice. Cancers (Basel). 2019 Sep 19;11(9): Authors: Imperial R, Nazer M, Ahmed Z, Kam AE, Pluard TJ, Bahaj W, Levy M, Kuzel TM, Hayden DM, Pappas SG, Subramanian J, Masood A Abstract Tumor heterogeneity, especially
- Long Non-Coding RNAs as Molecular Signatures for Canine B-Cell Lymphoma Characterization.Related ArticlesLong Non-Coding RNAs as Molecular Signatures for Canine B-Cell Lymphoma Characterization. Noncoding RNA. 2019 Sep 19;5(3): Authors: Cascione L, Giudice L, Ferraresso S, Marconato L, Giannuzzi D, Napoli S, Bertoni F, Giugno R, Aresu L Abstract BACKGROUND: Diffuse large B-cell lymphoma (DLBCL), marginal zone lymphoma (MZL) and follicular lymphoma (FL) are the most common B-cell lymphoma
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