Τετάρτη 25 Σεπτεμβρίου 2019

Predictive Value of Sentinel Lymph Node Biopsy in Cutaneous Squamous Cell Carcinoma Based on the AJCC-8 and Brigham and Women's Hospital Staging Criteria
BACKGROUND Recommendations on when to perform sentinel lymph node (SLN) biopsy in cutaneous squamous cell carcinoma (cSCC) are lacking despite the tumor's clear predilection for lymphatic spread. OBJECTIVE To analyze the frequency of SLN metastasis in published series of cSCC in the context of the eighth edition of the American joint Committee on Cancer (AJCC-8) and the Brigham and Women's Hospital (BWH) staging criteria. METHODS Systematic review of studies of patients with cSCC who underwent SLN biopsy that described biopsy results. RESULTS In total, 153 patients with 24 positive SLN biopsies (15.7%) were included. Based on the AJCC-8 criteria positivity rates in the T2 and T3 categories were 8.3% (1/12 patients) and 25% (8/32), respectively. Using the BWH system there were, 2/33 in category T2a (6.5%), and 5/17 in category T2b (29.8%). On applying the same criteria to tumors of the trunk and extremities the results were similar. CONCLUSION It would seem reasonable to recommend SLN biopsy for patients with AJCC-8 Stage T3+ disease or BWH Stage T2b/T3 disease. Both the AJCC-8 and the BWH systems would appear to be useful for staging cSCC of the trunk and extremities. Address correspondence and reprint requests to: Antonio Tejera-Vaquerizo, Servicio de Dermatología Instituto Dermatológico GlobalDerm, Calle Feria, 40, CP 14700, Palma del Río (Córdoba), Spain, or e-mail: antoniotejera@aedv.es Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.dermatologicsurgery.org). The authors have indicated no significant interest with commercial supporters. © 2019 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
Cutaneous Metastases in a Patient With Muir–Torre Syndrome
No abstract available
Improvement of Dupuytren Disease After Treatment With a Fractionated CO2 Laser
No abstract available
Intraoral Basal Cell Carcinoma Discovered During Mohs Micrographic Surgery
No abstract available
Reconstruction of a Large Glabellar Defect
No abstract available
Use of a Novel, Noninvasive Imaging System to Characterize Metabolic Changes in Subcutaneous Adipose Tissue After Cryolipolysis
No abstract available
A Physical Argument Against the Use of Small Syringes for Hyaluronic Acid Filler Injections
No abstract available
Epidemiology and Survival of Microcystic Adnexal Carcinoma by Sex in the United States
No abstract available
1550-nm Nonablative Fractional Laser Versus 10,600-nm Ablative Fractional Laser in the Treatment of Surgical and Traumatic Scars: A Comparison Study on Efficacy and Treatment Regimen
BACKGROUND The appearance and symptoms of scars can cause significant distress to patients. OBJECTIVE To assess and compare efficacy of the 1,500-nm nonablative fractional laser (NAFL) and 10,600-nm ablative fractional laser (AFL) in reducing symptoms and improving the appearance of traumatic or surgical scars. MATERIALS AND METHODS Single-center prospective, randomized, blinded, split-scar study was conducted on 100 patients with a scar obtained through trauma or surgery. Three treatments of NAFL or AFL were administered to each half of the scar at 4-week intervals. Scars were self-rated by the patient using the Patient and Observer Scar Assessment Scale and a satisfaction score and objectively evaluated by blinded dermatologists using the Manchester Scar Scale and visual analog scale. RESULTS Blinded observers found no statistically significant difference in scar appearance. Patient rating showed improvement of scar appearance (p < .0001). Pain was worse after treatment with AFL (p = .0492). Overall, there was no statistically significant evidence of one laser being superior or inferior to the other for patient and blinded observer scores (p = .3173 and p = .2513, respectively). CONCLUSION Scar treatment with AFL or NAFL is associated with high patient satisfaction. Objective evaluation of scars did not identify improvement in scar appearance. Address correspondence and reprint requests to: Pooja Chitgopeker, MBChB, Medical Dermatology Associates of Chicago, Chicago, IL 60654, or e-mail: Pooja.chitgopeker@gmail.com ASDS Cutting Edge Research Grant 2015. The authors have indicated no significant interest with commercial supporters. Reviewed and approved by Hawk IRB; approval #201509722. © 2019 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
Perineural Invasion With Thick Sheaths of Basal Cell Carcinoma in a Child After a History of Radiation Exposure
No abstract available

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