The Journal of Prosthetic Dentistry
- A technique for facilitating open-tray implant impressionsPublication date: Available online 24 September 2019Source: The Journal of Prosthetic DentistryAuthor(s): Stefan Wolfart, Burak Yilmaz
- Optimizing donor site analgesia after bone harvest from iliac crestPublication date: Available online 25 September 2019Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): D.R. Grimes, C. Frezzini, E.J. Grimes, J.E. Rowson, I.W. OrmistonAbstractAt Queens Medical Centre, Nottingham, alveolar bone grafts (ABG) for patients with cleft lip and palate (CLP) were performed by two surgeons following the same surgical protocol, but with different postoperative iliac crest donor site analgesia: surge
bioRxiv Subject Collection: Evolutionary Biology
- Ancient genomic regulatory blocks are a major source for gene deserts in vertebrates after whole genome duplications [NEW RESULTS]We investigated how the two rounds of whole genome duplication that occurred at the base of the vertebrate lineage have impacted ancient microsyntenic associations involving developmental regulators (known as genomic regulatory blocks, GRBs). We showed that the majority of GRBs present in the last common ancestor of chordates have been maintained as a single copy in humans. We found evidence that dismantling of the additional GRB copies occurred
- Transposable elements in individual genotypes of Drosophila simulans [NEW RESULTS]Transposable elements are mobile DNA sequences that are able to copy themselves within a host's genome. Within insects they often make up a substantial proportion of the genome. While they are the subject of intense research, often times when copy number is estimated it is estimated only at the population level, or in a limited number of individuals within a population. I was interested in whether or not transposable elements accumulate at differ
- Gene duplications trace mitochondria to the onset of eukaryote complexity [NEW RESULTS]The last eukaryote common ancestor (LECA) lived 1.6 billion years ago. It possessed nuclei, sex, an endomembrane system, mitochondria, and all key traits that make eukaryotic cells more complex than their prokaryotic ancestors. The closest known relatives of the host lineage that acquired the mitochondrion are, however, small obligately symbiotic archaea that lack any semblance of eukaryotic cell complexity. Although the steep evolutionary grade
- Aging, computation, and the evolution of neural regeneration processes [NEW RESULTS]Metazoans are capable of gathering information from their environments and respond in predictable ways. These computational tasks are achieved by means of more or less complex networks of neurons. Task performance must be reliable over an individual's lifetime and must deal robustly with the finite lifespan of cells or with connection failure - rendering aging a relevant feature in this context. How do computations degrade over an organism's life
- Combining α-Hederin with cisplatin increases the apoptosis of gastric cancer in vivo and in vitro via mitochondrial related apoptosis pathwayPublication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Huan Deng, Jingjing Ma, Yinghui Liu, Pengzhan He, Weiguo DongAbstractObjectCisplatin is a type of broad-spectrum anti-carcinogen that has been widely used in anti-gastric cancer therapy. Drug resistance prevails in gastric cancer therapy. α-Hederin has been reported to exert anti-tumour ability by inducing apoptosis in many cancers in vitro and in vivo. A c
- Guhong Injection promotes fracture healing by activating Wnt/beta-catenin signaling pathway <em>in vivo</em> and <em>in vitro</em>Publication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Zhizhen Sun, Hongting Jin, Huifen Zhou, Li Yu, Haitong Wan, Yu HeAbstractGuhong Injection (GHI), composed of aceglutamide and safflower aqueous extract, has been applied to the clinical treatment of orthopedic diseases, but the relevant mechanism by which GHI exerts effects on bone remodeling has not been reported. In the present study, we investigated the
- Comparative study on protective effect of hydrogen rich saline and adipose-derived stem cells on hepatic ischemia-reperfusion and hepatectomy injury in swinePublication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Qianzhen Zhang, Chenxi Piao, Jiayuan Xu, Zhihui Jiao, Yansong Ge, Xiaoning Liu, Yajun Ma, Hongbin WangAbstractAimTo compare and evaluate the hepatoprotective effect of liver parenchyma injection of ADSCs and portal vein injection of HRS in laparoscopic hepatic ischemia reperfusion combined with hepatectomy injury in miniature pigs.MethodsEighteen miniature
- The prognostic landscape of tumor-infiltrating immune cells in cervical cancerPublication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Jingnan Wang, Zhuoman Li, Aiqin Gao, Qing Wen, Yuping SunAbstractTumor-infiltrating immune cells (TICs) are highly relevant to tumor development and are promising prognostic biomarkers. However, the precise assessment of TICs is limited by the deficiencies of traditional measurements, such as the lack of phenotypic markers. Here, we analyzed the composition
PeerJ Computer Science
- The interplay between cognitive tasks and vision for upright posture balance in adolescentsBackground The control of an upright stance in humans is important in medicine, psychology, and physiology. The maintenance of upright stance balance depends not only on sensory information from proprioceptive, vestibular, cutaneous, and visual sources but also on cognitive resources. The present study investigated the effects of cognitive tasks while standing with eyes open on upright stance balance in adolescents. We hypothesiz
- The rediscovery of the rare Vietnamese endemic Eriophorum scabriculme redefines generic limits in the Scirpo-Caricoid Clade (Cyperaceae)For those familiar with boreal bogs and wet tundra, species of Eriophorum (“the cotton grasses”) will undoubtedly represent some of the most striking and memorable taxa they have encountered. This small genus of 20 Holarctic sedge species (Cyperaceae) is remarkable because its inflorescences produce large, brilliantly white to rusty-red cottony masses when its flowers develop a perianth of highly elongated bristles after anthesis. In this study,
- Cellular accumulation and cytotoxic effects of zinc oxide nanoparticles in microalga Haematococcus pluvialisBackground Zinc oxide nanoparticles (ZnO NPs) are widely used in household and cosmetic products which imply an increased releasing of these particles into the environment, especially aquatic ecosystems, resulting in the need of assessing the potential toxic effects of ZnO NPS on the aquatic organisms, particularly on microalgae which form the base for food chain of aquatic biota. The present study has investigated the dose- and time-dependent
- The effects of growth rate and biomechanical loading on bone laminarity within the emu skeletonThe orientation of vascular canals in primary bone may reflect differences in growth rate and/or adaptation to biomechanical loads. Previous studies link specific canal orientations to bone growth rates, but results between different taxa are contradictory. Circumferential vascular canals (forming laminar bone) have been hypothesized to reflect either (or both) rapid growth rate or locomotion-induced torsional loading. Previous work on the hindli
- Cloning of a new HSP70 gene from western flowerthrips, Frankliniella occidentalis, and expression patterns during thermal stressFrankliniella occidentalis (Pergande) is an invasive pest that endangers a wide variety of horticultural and agronomic crops. HSP70 is the most important member of the heat shock protein (HSP) family and plays an important role in insect thermal tolerance. In this study, a new gene encoding HSP70 from F. occidentalis, Fohsp706, was selected from the F. occidentalis transcriptome exposed to thermal stress (40 °C) and cloned by RT-PCR and RACE. Fur
- Bar-HRM: a reliable and fast method for species identification of ginseng (Panax ginseng, Panax notoginseng, Talinum paniculatum and Phytolacca Americana)Background Korean ginseng has long been famous and is one of the most well known forms of ginseng. The root of plants in the genus Panax is commonly recognized as ginseng. Different Panax species of ginseng root have been used as treatments. Although many other herbs are called ginseng, they do not contain the active compounds of ginsenosides. In Thailand, we have Thai ginseng which is of course not one of Panax species. Thai gin
- Effect of reduced pH on physiology and shell integrity of juvenile Haliotis iris (pāua) from New ZealandThe New Zealand pāua or black footed abalone, Haliotis iris, is one of many mollusc species at potential risk from ocean acidification and warming. To investigate possible impacts, juvenile pāua (~24 mm shell length) were grown for 4 months in seawater pH/pCO2 conditions projected for 2100. End of century seawater projections (pHT 7.66/pCO2 ~1,000 μatm) were contrasted with local ambient conditions (pHT 8.00/pCO2 ~400 μatm) at two typical tempera
- Development of a highly sensitive magneto-enzyme lateral flow immunoassay for dengue NS1 detectionBackground Dengue infection represents a global health issue of growing importance. Dengue non-structural protein 1 (NS1) plays a central role in the early detection of the disease. The most common method for NS1 detection is testing by lateral flow immunoassays (LFIAs) with varying sensitivity. In this study, we present a highly sensitive magneto-enzyme LFIA for prompt diagnosis of dengue. Methods We have demonstrated the development
- Soil warming increases soil temperature sensitivity in subtropical Forests of SW ChinaBackground Soil respiration (RS) plays an important role in the concentration of atmospheric CO2 and thus in global climate patterns. Due to the feedback between RS and climate, it is important to investigate RS responses to climate warming. Methods A soil warming experiment was conducted to explore RS responses and temperature sensitivity (Q10) to climate warming in
- Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cellsBackground Synthetic cannabinoids are a commonly used class of recreational drugs that can have significant adverse effects. There have been sporadic reports of co-consumption of illicit drugs with rodenticides such as warfarin and brodifacoum (BFC) over the past 20 years but recently, hundreds of people have been reported to have been poisoned with a mixture of synthetic cannabinoids and BFC. We have sought to establish whether
- Genetic diversity, functional properties and expression analysis of NnSBE genes involved in starch synthesis of lotus (Nelumbo nucifera Gaertn.)Background Starch branching enzyme (SBE) is one of the key enzymes in starch biosynthetic metabolism, determining amylopectin structure. Methods Full length coding sequences (CDS) of SBE genes were cloned using reverse transcription PCR (RT-PCR) technology, and neighbor-joining (NJ) tree was used for phylogenetic analysis. Single nucleotide polymorphisms (SNPs) were
- Identification of genes encoding ALMT and MATE transporters as candidate aluminum tolerance genes from a typical acid soil plant, Psychotria rubra (Rubiaceae)To understand how tropical plants have adapted to acid soils, we analyzed the transcriptome of seedlings of Psychotria rubra, a typical species found on acid soils. Using RNA-seq, we identified 22,798 genes, including several encoding proteins of the Al3+-activated malate transporter (ALMT) and multidrug and toxic compound extrusion (MATE) families. Molecular phylogenetic analysis of ALMTs and MATEs revealed the grouping of those from P. rubra, w
- Human disturbance caused stronger influences on global vegetation change than climate changeGlobal vegetation distribution has been influenced by human disturbance and climate change. The past vegetation changes were studied in numerous studies while few studies had addressed the relative contributions of human disturbance and climate change on vegetation change. To separate the influences of human disturbance and climate change on the vegetation changes, we compared the existing vegetation which indicates the vegetation distribution un
- Cloning expression and immunogenicity analysis of inhibin gene in Ye Mule Aries sheepBackground Ye Mule Aries sheep is one of the most important sheep breeds in Xinjiang, China. This breed is well adapted to harsh environmental conditions and displays strong disease resistance, fast growth, and high cold tolerance. To analyze the clonal expression and immunogenicity of the Ye Mule Aries sheep inhibin gene, total RNA was extracted from sheep ovarian tissue and used as a template to generate a eukaryotic expression
Case Reports in Oncology
- Performance Status Assessment by Using ECOG (Eastern Cooperative Oncology Group) Score for Cancer Patients by Oncology Healthcare ProfessionalsMedical literature does not have clear consensus on inter-rater reliability of PS assessment by different oncology health care professionals (HCPs) although it plays an important role in treatment decision and prognosis for oncology patients. Eastern Cooperative Oncology Group (ECOG) and Karnofsky performance status (KPS) scores are commonly used for this purpose by oncology HCPs around the world. This study was conducted to find variability or s
- Clinical Validation of Quality Improvements Using the Six Sigma Concept: A Case Study for Deep Brain Stimulation in Parkinson’s DiseaseBackground: The Six Sigma concept allows for the evaluation of quality changes after the implementation of new technical equipment or adjustment of perioperative procedures. Exemplarily, we applied this method for quality assessment in deep brain stimulation surgery (DBS) for Parkinson’s disease. Methods: The medical procedure and possible errors were registered. Then, 6 critical-to-quality characteristics regarding clinical outcome, surgical pre
Operative Techniques in Otolaryngology
- Operative management of benign nonepithelial solid laryngeal tumorsMost benign tumors of the larynx are epithelial in origin, with nearly 85% being laryngeal papilloma. Nonepithelial laryngeal tumors are uncommon and more than 50% of these are malignant. Therefore, benign nonepithelial solid tumors of the larynx are quite rare. The management of these tumors varies based on the site of origin, specific pathology, tumor size, and risk for malignant transformation. Most are ultimately treated with complete surgica
- Surgery for adult laryngeal papillomatosisRecurrent laryngeal papillomatosis is a viral (human papillomavirus) disease that causes the growth of epithelial verrucous lesions. Patients with laryngeal papillomatosis undergo multiple surgeries due to the tendency of the lesions to reoccur and cause recurrent voice and breathing problems. The goal of the surgical treatment is to remove the lesions while protecting the delicate layered structure of the vocal folds in order to prevent scarring
- Instrumentation in endoscopic laryngeal surgeryThe development of transoral endoscopic approaches to the larynx have revolutionized the way we evaluate and treat various laryngeal pathologies. Nowadays, there is a large spectrum of laryngoscopes to address the various age groups, clinical needs, laryngeal pathologies, and subsites. The current paper is a review of some of the various laryngeal instruments used today in the evaluation and treatment of laryngeal pathologies, The review will cov
- Endoscopic surgical approach to laryngoceles and saccular cystsLaryngeal saccular disorders are rare lesions presenting as abnormal saccular dilation, either mainly filled with air (laryngoceles) or fluid (saccular cysts). These are further categorized as internal when confined in the endolarynx, external, or combined. In adults, saccular disorders are mostly idiopathic with various reported proportion associated with laryngeal cancer or increased transglottic pressure. Patients may present with voice disord
- Airway management in laryngeal surgeryAirway management and anesthesia for laryngeal surgery poses many challenges. A preoperative endoscopic airway examination and discussion with the otolaryngologist helps in planning the anesthetic management. Although, securing the airway using specialized endotracheal tubes is possible in the majority of cases, the surgeon may occasionally request a ‘tubeless’ field. This can be achieved by ventilating the lungs using jet ventilation or high flo
- Open surgical approach to laryngoceles and saccular cystsSaccular disorders extending beyond the thyrohyoid membrane are classified as external, or combined, based on to their extension beyond the thyrohyoid membrane and the proportion of the external to the internal component. The workup is the same as for internal saccular disorders and airway safety is of utmost importance. The open/transcervical approach is currently the treatment of choice for cases with relatively large external component. Endosc
- Laryngeal imagingThe purpose of this article is to describe key anatomic feature of the larynx and to review contemporary imaging protocols for the evaluation of nonmalignant lesions and pathologies of the larynx. The role of computed tomography (CT), Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) CT in the evaluation of laryngeal pathologies will be addressed. Imaging feature in CT and MRI is discussed in particular conditions, such as c
- IntroductionThe larynx is a highly complex organ involved with breathing, phonation and swallowing. Its unique architecture and intricate mechanics involve numerous cartilages, tendons, muscles, nerves, mucosal folds and joints, packed together in a tight compartment.
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου