Intraperitoneal hemorrhage during pregnancy and parturition: Case reports and literature review We aim to investigate the diagnosis, treatment, and prognosis of intraperitoneal hemorrhage during pregnancy and parturition. Three cases with intraperitoneal hemorrhage during pregnancy and parturition admitted to our hospital from Jan. 2008 to Jan. 2018 were included in this study. One case showed fetal distress. Abdominal ultrasonography and abdominal CT showed pyoperitoneum in 2 cases. Abdominal puncture was performed in 2 patients, and noncoagulant blood was collected. The indications of emergency caesarean section in 3 cases were intraperitoneal hemorrhage. The etiology included rupture of posterior wall of uterus, rupture of blood vessel on uterine surface, and rupture of inflammatory vessel on uterine surface, respectively. The average volume of intraperitoneal bleeding was 2630 ml, and the average transfusion volume was 1530 ml. Caesarean section, and suture hemostasis were performed in 3 cases. The gestational age of delivery were 40+6 weeks, 40+2 weeks, and 25+5 weeks, respectively. There were 1 stillborn fetus and 2 live infants. All the puerperas were cured and discharged. Intraperitoneal hemorrhage in pregnancy is rare and is easily misdiagnosed. The mortality of pregnant women and perinatal infant is high. Therefore, early diagnosis, and timely operation is important. |
Acupoint-tuina therapy promotes lactation in postpartum women with insufficient milk production who underwent caesarean sections Breast milk is recognized and strongly recommended by the World Health Organization (WHO) as the optimal feeding for all babies. Breastfeeding is associated with better nutritional and non-nutritional outcomes when compared to formula feeding, and has proven health benefits to both infants and their mothers. This clinical research is to examine the feasibility and efficacy of Acupoint-Tuina therapy in treating postpartum women who underwent C-sections and suffered from insufficient milk production. The patients in the control group received standard medical care, while the patients in the Tuina group received Tuina therapy during the next 48 hours in addition to standard care, given once daily for 2 days. To evaluate the efficacy of Tuina therapy, patients of both groups were assessed for surface temperature of breasts, volume of breasts, volume of breast milk production, serum PRL level, and uterus recovery at various time points. Tuina therapy significantly increased the milk production when compared to the control group, for as much as 13-fold and 10-fold of that in the control group on the third and fourth postpartum days. In addition, Tuina therapy also significantly increased the full breast enlargement and the serum PRL level change, and decreased the breast surface temperature rise. Last but not the least, Tuina therapy also accelerated the post-surgery recovery of uterus. During the early postpartum days, Tuina therapy increases the milk production and promotes other physiological changes supporting lactation for postpartum women with C-section delivery and insufficient breast milk production. The novel intervention is warranted for further investigation and validation. |
Gastroenteritis during infancy is a novel risk factor for allergic disease Antibiotics during infancy, delivery, and breastfeeding affect the intestinal microbiota in early life and is associated with allergic disease. Gastroenteritis (GE) during infancy also affects intestinal microbiota in early life, however, its relationship to allergic disease has not been investigated. Data of 45,499 males and 49,430 females, from birth to 5 years of age, were collected from a national database in Taiwan. Subjects were categorized into early GE (GE within 0–6 months) and non-early GE group (no GE within 0–6 months). The rates of asthma (AS), allergic rhinitis (AR), and atopic dermatitis (AD) over 5 years were evaluated and compared between the groups. In patients with AS, AR, and AD, the number of clinical visits and drug prescriptions for the allergic disease was also evaluated to assess the effect of early GE on allergic disease. After adjusting for the effect of GE in later life and other factors, the rates of AS [OR (odds ratio) 1.54, 95% confidence interval (CI) 1.48–1.60], AR [OR 1.49, 95% CI 1.45–1.54], and AD [OR 1.40, 95% CI 1.33–1.47] were higher in the early GE group than in the non-early GE group. The magnitude of the increase was higher in females than in males. In those with AS, AR, and AD, the number of clinical visits and drug prescriptions was not different between the early GE and non-early GE groups. In children with early GE, good control of GE in the following years lowered the rate of allergic disease. Early-life GE was associated with increased rates of AS, AR, and AD in later life and this was trend more prominent in females. |
GPR137 is a promising novel bio-marker for the prognosis of bladder cancer patients Objectives: G protein-coupled receptor 137 (GPR137) was reported to be associated with several cancers, but its role in bladder cancer has not been reported. The purpose of this study was to evaluate clinical significance of GPR137 in bladder cancer. Methods: The expressions of GPR137 in pathological tissues and corresponding normal tissues from bladder cancer patients were detected via quantitative real time polymerase chain reaction (qRT-PCR). Western blot was performed to detect GPR137 expression in bladder cancer tissues and adjacent normal tissues. Chi-Squared test analyzed the relationship between GPR137 expression and clinical features of bladder cancer patients. Additionally, Kaplan–Meier method was adopted in estimating overall survival of bladder cancer patients. Prognostic value of GPR137 was evaluated through Cox regression analysis. Results: The expression of GPR137 mRNA and protein in pathological tissues was significantly higher than that in adjacent normal tissues (P < .001). Moreover, similar result was found for bladder cancer patients and healthy controls (P < .001). And GPR137 expression was associated with tumor size (P = .006) and TNM stage (P = .012). The results of Kaplan–Meier analysis suggested that patients with high expression of GPR137 had shorter overall survival time than those with low expression (Log rank test, P = .001). Cox regression analysis indicated that GPR137 could act as an independent biomarker for bladder cancer prognosis (HR = 1.850, 95% CI = 1.272–2.689, P = .001). Conclusion: Abnormal expression of GPR137 is associated with bladder cancer and GPR137 is a potential biomarker for the therapy and prognosis of bladder cancer. |
A CARE-compliant article: ipsilateral progressive idiopathic lipid keratopathy: A case report Rationale: Lipid deposition on the cornea without previous infection, inflammation, vascularization, or trauma is idiopathic lipid keratopathy. In vivo laser confocal microscopy (IVCM) and anterior segment optical coherence tomography (AS-OCT) are 2 noninvasive methods that can help identify the structures and morphological characteristics of the focus. Patient concerns: A 63-year-old woman with ipsilateral corneal lipid deposits developing from a small white spot into a yellow-white superotemporal elliptic shape within a year. AS-OCT showed peripheral deep stromal deposits. IVCM showed hyper-reflective material with typical crystalline-like or needle-like structures in the superotemporal area. Diagnosis: Idiopathic lipid degeneration. Interventions: Topical steroids eye drops 3 times a day for a month and further consultation every 3 months. Outcomes: This patient of idiopathic lipid keratopathy was observed every 3 months and till now we have reviewed this patient twice. Topical steroids eye drops were only used during the first month. No further development was observed about the lesion and the patient's visual acuity remained good. Conclusion: IVCM and AS-OCT can help identify the characteristic crystalline-like or needle-like hyper-reflective material that could help diagnosis of idiopathic lipid degeneration. |
The role of 18F-FDG PET/CT in management of paraneoplastic limbic encephalitis combined with small cell lung cancer: A case report Rationale: Limbic encephalitis is one of the most common paraneoplastic neurological disorders (PND). The role of brain Fluorine-18-fluorodeoxyglucose position emission tomography/computed tomography (CT) in paraneoplastic limbic encephalitis (PLE) and of the whole body 18F-FDG PET/CT in this setting, remains still not well defined. Patient concerns: We report a case of a patient with chronic inflammatory rheumatism, psoriasis and Hashimoto thyroiditis and subsequent appearance of static and dynamic ataxia and episodic memory deficit who was diagnosed as PLE combined with small cell lung cancer (SCLC). Diagnoses: The diagnosis of SCLC was made with EBUS-TBNA of a mediastinal lymph node. Interventions: Whole-body 18F-FDG PET/CT was performed for the initial staging of SCLC, in the planning of radiotherapy treatment, to evaluate therapeutic response and in the follow-up. A dedicated brain scan was included to the same PET session. Whole-body contrast enhanced computed tomography (CT) and contrast enhanced whole-brain MRI were also performed. Outcomes: She was administered neoadjuvant chemioterapy with Cisplatin and Etoposide with concomitant radiotherapy treatment. Whole body 18F-FDG PET/CT showed a complete metabolic response already after 3 cycles of chemioterapy. Brain functional study showed a metabolic pattern characterized by the migration of hypermetabolism in the bilateral hippocampal areas during the therapeutic treatment, which correlated with the persistence of clinical symptoms. Lessons: In the era of personalized medicine and targeted therapy, this case highlights the importance of the 18F-FDG PET/CT study as an accurate tool to identify PLE and to guide the diagnostic work-up of the underlying tumor. Considering that most of these are 18F-FDG avid tumors and that the 18F-FDG PET/CT scan is often added to the diagnostic work-up when screening patients for malignancy, this functional imaging can play a decisive role. |
Fermented milk containing Lactobacillus paracasei and Glycyrrhiza glabra has a beneficial effect in patients with Helicobacter pylori infection: A randomized, double-blind, placebo-controlled study Background: Lactobacillus paracasei and Glycyrrhiza glabra have been reported as having beneficial effects on Helicobacter pylori infection. We aimed to assess the efficacy and safety of fermented milk containing L paracasei HP7 and G glabra in patients with H pylori infection. Methods: This multicenter, prospective, randomized, double-blind, placebo-controlled clinical trial was conducted in 2 hospitals from April to December 2017. Patients with H pylori infection were randomized into either the treatment group (fermented milk with L paracasei HP7 and G glabra) or placebo group (fermented milk only) once daily for 8 weeks. The primary endpoint was the gastric load of H pylori measured by 13C-urea breath test (UBT). Secondary endpoints were histologic and clinical improvement. Results: A total of 142 patients were randomly allocated to the treatment (n = 71) or placebo groups (n = 71). Compared to baseline data, the quantitative value of 13C-UBT at 8 weeks was significantly reduced in the treatment group (from 20.8 ± 13.2% to 16.9 ± 10.8%, P = .035), but not in the placebo group (P = .130). Chronic inflammation improved significantly only in the treatment group (P = .013), whereas the neutrophil activity deteriorated significantly only in the placebo group (P = .003). Moreover, the treatment group had significant improvement in gastrointestinal symptoms (P = .049) and quality of life (P = .029). No serious adverse events were observed. Conclusion: The combination of fermented milk containing L paracasei and G glabra reduced H pylori density and improved histologic inflammation. However, their mechanisms of action should be elucidated in further studies. |
A case report of spontaneous coronary artery dissection complicated by stent fracture Rationale: Spontaneous coronary artery dissection (SCAD) is a rare, complex disease, and nowadays poorly understood. The overall incidence of SCAD ranges from 0.28% to 1.1% in angiographic studies. Therefore, the true incidence of SCAD is most likely underestimated due to asymptomatic or sudden cardiac death before diagnosis. Stent fracture (SF) is a multifactorial issue. Longer vessel remodeled by 2 stents can be more prone to have SF due to higher radial force. Patient concerns: In this paper we report a 48-year-old man with chest pain for 2 years. Diagnoses: Elective coronary angiography revealed a linear dissection in obtuse marginal branch (OM). Interventions: He underwent percutaneous coronary intervention (PCI) with the guidance of intravascular ultrasound (IVUS). Outcomes: Then SF was revealed 9 months later. Lessons: This is the first case report of SF after coronary intervention therapy in SCAD patients. |
Endoscopy and magnetic resonance imaging-based prediction of ypT stage in patients with rectal cancer who received chemoradiotherapy: Results from a prospective study of 110 patients Accurate tumor response determination remains inconclusive after preoperative chemoradiation therapy (CRT) for rectal cancer. This study aimed to investigate whether clinical assessment, such as endoscopy and magnetic resonance imaging (MRI), can accurately predict ypT stage and select candidates for pelvic organ-preserving surgery in rectal cancer after preoperative CRT. A total of 110 patients who underwent preoperative CRT followed by curative resection for rectal cancer were prospectively enrolled. Magnetic resonance tumor regression grade (mrTRG) using T2-MRI, endoscopic evaluation, and combination modality (combination of endoscopy and mrTRG) were used to analyze tumor response after preoperative CRT. Endoscopic findings were categorized as 3 grades and the mrTRG was assessed into 5 grades. Twenty-nine patients (26.4%) had achieved pathologic complete response. When predicting ypT0, endoscopy showed significantly higher area under the curve (AUC 0.818) than did mrTRG (AUC 0.568) and combination modality (AUC 0.768) in differentiating good response from poor response (P < .001). Both endoscopy and combination modality showed significantly higher diagnostic performance in sensitivity (79.31%), positive predictive value (PPV 67.65%), negative predictive value (NPV 92.11%), and accuracy (84.55%) than those of MR tumor response (sensitivity 37.93%, PPV 36.67%, NPV 77.50%, and accuracy 66.36%) for the prediction of ypT0 (P < .001). Combination modality showed significantly higher diagnostic performance in sensitivity (56.92%), NPV (56.92%), and accuracy (67.27%) compared with those of mrTRG. Neither endoscopy, nor mrTRG, nor the combination modality had adequate diagnostic performances to be clinically acceptable in selecting candidates for nonoperative treatment strategies. However, endoscopy may be incorporated in clinical restaging strategy in planning the extent of surgical resection in patients with rectal cancer. |
A preliminary prospective study of patients who underwent vacuum-assisted and mesh-mediated fascial traction techniques for open abdomen management with negative fluid therapy: An observational study It is unclear whether strategies targeting negative fluid balance are associated with facilitated early fascial closure. The present study investigated the effects of fluid removal therapy on early facial closure of open abdomen patients. A prospective study was conducted in patients who underwent open abdomen management with vacuum-assisted and mesh-mediated fascial traction technique. Therapeutic diuresis with torasemide was applied to cause negative fluid balance in the treatment group. The study and follow-up periods were 7 and 180 days, respectively. The observational indices included the intra-abdominal pressure, the number of days to closure, the type of closure, the septic complications, the duration of ventilation support, the duration of initial hospital stay, and the duration of intensive care unit (ICU) stay. A total of 27 patients were divided into the treatment (16 patients) and control (11 patients) groups. The median intra-abdominal pressure (IAP) of the patients of the control and the treatment groups was significantly lower at day 7 compared with the baseline value (P < .0001). IAP was lower in the treatment group compared with that noted in the control group, following day 4 of the fluid removal therapy (P < .05). The percentage weight loss in the treatment group was between 4.80% and 10.88%. The early closure rates were significantly higher in the treatment group compared with those in the control group (75.0% vs 18.2%, P = .0063). Fluid removal therapy combined with vacuum-assisted and mesh-mediated fascial traction provided a high early fascial closure rate for open abdomen patients. |
Observational Study |
Intraperitoneal hemorrhage during pregnancy and parturition: Case reports and literature review
Yalan Xu, Yuxiang Zhou, Junshu Xie, Xiuju Yin, Xiaohong Zhang
Yalan Xu, Yuxiang Zhou, Junshu Xie, Xiuju Yin, Xiaohong Zhang
Acupoint-tuina therapy promotes lactation in postpartum women with insufficient milk production who underwent caesarean sections
Ping Lu, Zhi-qi Ye, Jin Qiu, Xiao-yu Wang, Juan-juan Zheng
Ping Lu, Zhi-qi Ye, Jin Qiu, Xiao-yu Wang, Juan-juan Zheng
Gastroenteritis during infancy is a novel risk factor for allergic disease
Hui-Hsien Pan, Ko-Huang Lue, Hai-Lun Sun, Min-Sho Ku
Hui-Hsien Pan, Ko-Huang Lue, Hai-Lun Sun, Min-Sho Ku
GPR137 is a promising novel bio-marker for the prognosis of bladder cancer patients
Jianlei Lu, Feng Zhong, Beibei Sun, Chao Wang
Jianlei Lu, Feng Zhong, Beibei Sun, Chao Wang
A preliminary prospective study of patients who underwent vacuum-assisted and mesh-mediated fascial traction techniques for open abdomen management with negative fluid therapy: An observational study
Weiliang Tian, Qian Huang, Zheng Yao, Ming Huang, Fan Yang, Yunzhao Zhao, Jieshou Li
Weiliang Tian, Qian Huang, Zheng Yao, Ming Huang, Fan Yang, Yunzhao Zhao, Jieshou Li
Gut microbiota shifts in patients with gastric cancer in perioperative period
Weiren Liang, Yan Yang, Haiyong Wang, Haohao Wang, Xiongfei Yu, Yimin Lu, Shengrong Shen, Lisong Teng
Weiren Liang, Yan Yang, Haiyong Wang, Haohao Wang, Xiongfei Yu, Yimin Lu, Shengrong Shen, Lisong Teng
Safety issues related to the electronic cross-matching of blood in mainland China: A prospective cohort study involving cross-matching of 40,228 blood samples
Yuan-Jie Wang, Jia-Rui Liu, Yong Liu
Yuan-Jie Wang, Jia-Rui Liu, Yong Liu
Endoscopic findings and outcome in caustic ingestion of acidic and alkaline agents in adults: A retrospective analysis
Marcus Hollenbach, Jan Tünnemann, Manuel Florian Struck, Jürgen Feisthammel, Tobias Schlosser, Tiffany Schaumburg, Joachim Mössner, Albrecht Hoffmeister
Marcus Hollenbach, Jan Tünnemann, Manuel Florian Struck, Jürgen Feisthammel, Tobias Schlosser, Tiffany Schaumburg, Joachim Mössner, Albrecht Hoffmeister
The role of grade of injury in non-operative management of blunt hepatic and splenic trauma: Case series from a multicenter experience
Paolo Ruscelli, Alessandro Gemini, Massimiliano Rimini, Sergio Santella, Roberto Candelari, Marzia Rosati, Enrico Paci, Vittorio Marconi, Claudio Renzi, Rita Commissari, Roberto Cirocchi, Alberto Santoro, Vito D’Andrea, Amilcare Parisi
Paolo Ruscelli, Alessandro Gemini, Massimiliano Rimini, Sergio Santella, Roberto Candelari, Marzia Rosati, Enrico Paci, Vittorio Marconi, Claudio Renzi, Rita Commissari, Roberto Cirocchi, Alberto Santoro, Vito D’Andrea, Amilcare Parisi
Mortality risk factors in children with severe influenza virus infection admitted to the pediatric intensive care unit
Tingting Shi, Zhiqiang Nie, Li Huang, Huifeng Fan, Gen Lu, Diyuan Yang, Dongwei Zhang
Tingting Shi, Zhiqiang Nie, Li Huang, Huifeng Fan, Gen Lu, Diyuan Yang, Dongwei Zhang
Clinical outcomes of endoscopic balloon dilatation of intestinal strictures in patients with Crohn's disease
Ophir Winder, Naomi Fliss-Isakov, Gilad Winder, Erez Scapa, Henit Yanai, Sophie Barnes, Roy Dekel, Iris Dotan, Nitsan Maharshak
Ophir Winder, Naomi Fliss-Isakov, Gilad Winder, Erez Scapa, Henit Yanai, Sophie Barnes, Roy Dekel, Iris Dotan, Nitsan Maharshak
Integrase strand-transfer inhibitors for treatment of early HIV infection: A case series
Ramón Teira, Mar Gutierrez, Pepa Galindo, Elisa Martínez, Pepa Muñoz, Belén de la Fuente, Francisco Téllez, Marta Montero
Ramón Teira, Mar Gutierrez, Pepa Galindo, Elisa Martínez, Pepa Muñoz, Belén de la Fuente, Francisco Téllez, Marta Montero
Survey of job burnout and depression in standardized residency training programs in China
Yun Zhang, Xiaotian Chu, Yue Sha, Xuejun Zeng, Ti Shen
Yun Zhang, Xiaotian Chu, Yue Sha, Xuejun Zeng, Ti Shen
Effects of inferior alveolar nerve rupture on bone remodeling of the mandible: A preliminary study
Hongzhou Shen, Shuze Wang, Yin Zhi, Jiawen Si, Jun Shi
Hongzhou Shen, Shuze Wang, Yin Zhi, Jiawen Si, Jun Shi
“A contemporary description of staphylococcus aureus prosthetic valve endocarditis. Differences according to the time elapsed from surgery”
Carmen Sáez, Cristina Sarriá, Isidre Vilacosta, Carmen Olmos, Javier López, Pablo Elpidio García-Granja, Cristina Fernández, Carmen de las Cuevas, Guillermo Reyes, Lourdes Domínguez, Jose Alberto San Román
Carmen Sáez, Cristina Sarriá, Isidre Vilacosta, Carmen Olmos, Javier López, Pablo Elpidio García-Granja, Cristina Fernández, Carmen de las Cuevas, Guillermo Reyes, Lourdes Domínguez, Jose Alberto San Román
The effect of a comprehensive care and rehabilitation program on enhancing pelvic floor muscle functions and preventing postpartum stress urinary incontinence
Xiaowen Qi, Juan Shan, Lei Peng, Cuihong Zhang, Fanglei Xu
Xiaowen Qi, Juan Shan, Lei Peng, Cuihong Zhang, Fanglei Xu
Apatinib as an optional treatment in metastatic colorectal cancer
Aiyi Li, Kong Wang, Aiguo Xu, Gang Wang, Yongchang Miao, Zhichao Sun, Jingyu Zhang
Aiyi Li, Kong Wang, Aiguo Xu, Gang Wang, Yongchang Miao, Zhichao Sun, Jingyu Zhang
Galectin-9 in autoimmune hepatitis: Correlation between serum levels of galectin-9 and M2BPGi in patients with autoimmune hepatitis
Naoki Matsuoka, Hideko Kozuru, Tomohiro Koga, Seigo Abiru, Kazumi Yamasaki, Atsumasa Komori, Yuya Fujita, Junpei Tenmoku, Tomoyuki Asano, Shuzo Sato, Eiji Suzuki, Makiko Furuya, Hiroko Kobayashi, Hiroshi Watanabe, Atsushi Naganuma, Kaname Yoshizawa, Masaaki Shimada, Keisuke Ario, Haruhiro Yamashita, Hiroshi Kohno, Toshihiko Kaneyoshi, Minoru Nakamura, Hiroshi Furukawa, Atsushi Takahashi, Atsushi Kawakami, Hiromasa Ohira, Hiroshi Yatsuhashi, Kiyoshi Migita
Naoki Matsuoka, Hideko Kozuru, Tomohiro Koga, Seigo Abiru, Kazumi Yamasaki, Atsumasa Komori, Yuya Fujita, Junpei Tenmoku, Tomoyuki Asano, Shuzo Sato, Eiji Suzuki, Makiko Furuya, Hiroko Kobayashi, Hiroshi Watanabe, Atsushi Naganuma, Kaname Yoshizawa, Masaaki Shimada, Keisuke Ario, Haruhiro Yamashita, Hiroshi Kohno, Toshihiko Kaneyoshi, Minoru Nakamura, Hiroshi Furukawa, Atsushi Takahashi, Atsushi Kawakami, Hiromasa Ohira, Hiroshi Yatsuhashi, Kiyoshi Migita
Relationships between the femoral neck-preserving ratio and radiologic and clinical outcomes in patients undergoing total-hip arthroplasty with a collum femoris-preserving stem
Zeming Liu, Hongpeng Hu, Sikai Liu, Jia Huo, Mengnan Li, Yongtai Han
Zeming Liu, Hongpeng Hu, Sikai Liu, Jia Huo, Mengnan Li, Yongtai Han
The effect of tracheostomy delay time on outcome of patients with prolonged mechanical ventilation: A STROBE-compliant retrospective cohort study
Hsueh-Ping Tai, David Lin Lee, Chiu-Fan Chen, Yuh-Chin Tony Huang
Hsueh-Ping Tai, David Lin Lee, Chiu-Fan Chen, Yuh-Chin Tony Huang
Overall survival of colorectal cancer by stage at diagnosis: Data from the Martinique Cancer Registry
Clarisse Joachim, Jonathan Macni, Moustapha Drame, Audrey Pomier, Patrick Escarmant, Jacqueline Veronique-Baudin, Vincent Vinh-Hung
Clarisse Joachim, Jonathan Macni, Moustapha Drame, Audrey Pomier, Patrick Escarmant, Jacqueline Veronique-Baudin, Vincent Vinh-Hung
Differentiating pancreatic neuroendocrine tumors from pancreatic ductal adenocarcinomas by the “Duct-Road Sign”: A preliminary magnetic resonance imaging study
Bo Xiao, Zhi-Qiong Jiang, Jin-Xiang Hu, Xiao-Ming Zhang, Hai-Bo Xu
Bo Xiao, Zhi-Qiong Jiang, Jin-Xiang Hu, Xiao-Ming Zhang, Hai-Bo Xu
Clinical application of auricular point sticking in perioperative hemostasis for elderly patients with intertrochanteric fractures of the femur
Chunfang Yin, Jincun Zhang, Zhaojuan Er
Chunfang Yin, Jincun Zhang, Zhaojuan Er
HPV testing on vaginal/cervical nurse-assisted self-samples versus clinician-taken specimens and the HPV prevalence, in Adama Town, Ethiopia
Eshetu Lemma Haile, Simoens Cindy, Benoy Ina, Gurja Belay, Van geertruyden Jean-Pierre, Ransom Sharon, Lebelo Ramokone Lisbeth, Bogers Johannes Paul
Eshetu Lemma Haile, Simoens Cindy, Benoy Ina, Gurja Belay, Van geertruyden Jean-Pierre, Ransom Sharon, Lebelo Ramokone Lisbeth, Bogers Johannes Paul
Association of rs10204525 genotype GG and rs2227982 CC combination in programmed cell death 1 with hepatitis B virus infection risk
Chunhong Huang, Tiantian Ge, Caixia Xia, Wei Zhu, Lichen Xu, Yunyun Wang, Fengtian Wu, Feifei Liu, Min Zheng, Zhi Chen
Chunhong Huang, Tiantian Ge, Caixia Xia, Wei Zhu, Lichen Xu, Yunyun Wang, Fengtian Wu, Feifei Liu, Min Zheng, Zhi Chen
Challenges of transarterial therapy for hepatocellular carcinoma in patients with chronic kidney disease
Wei-Chen Lin, Chen-Wang Chang, Ching-Wei Chang, Tsang-En Wang, Ming-Jen Chen, Horng-Yuan Wang
Wei-Chen Lin, Chen-Wang Chang, Ching-Wei Chang, Tsang-En Wang, Ming-Jen Chen, Horng-Yuan Wang
Effects of Urinary Kallidinogenase on NIHSS score, mRS score, and fasting glucose levels in acute ischemic stroke patients with abnormal glucose metabolism: A prospective cohort study
Lei Chen, Lianxia Geng, Junmin Chen, Yan Yan, Lan Yang, Jing Zhao, Qian Sun, Junna He, Lin Bai, Xiaopeng Wang
Lei Chen, Lianxia Geng, Junmin Chen, Yan Yan, Lan Yang, Jing Zhao, Qian Sun, Junna He, Lin Bai, Xiaopeng Wang
Impact of bedside percutaneous dilational and open surgical tracheostomy on intracranial pressure, pulmonary gas exchange, and hemodynamics in neurocritical care patients
Martin Kieninger, Martin Windorfer, Christoph Eissnert, Nina Zech, Sylvia Bele, Florian Zeman, Elisabeth Bründl, Bernhard Graf, Holger Künzig
Martin Kieninger, Martin Windorfer, Christoph Eissnert, Nina Zech, Sylvia Bele, Florian Zeman, Elisabeth Bründl, Bernhard Graf, Holger Künzig
Are heart doses associated with survival in patients with non-small cell lung cancer who received post-operative thoracic radiotherapy?: A national population-based study
Chia Ching Lee, Gail Wan Ying Chua, Huili Zheng, Yu Yang Soon, Ling Li Foo, Anuradha Thiagarajan, Swee Peng Yap, Tian Rui Siow, Wee Loon Ng, Kevin Lee Min Chua, Connie Yip, Brendan Seng Hup Chia, Yan Yee Ng, Zubin Master, Poh Wee Tan, Yun Inn Tan, Yuh Fun Leong, Joan Faith Evacula Loria, Balamurugan Vellayappan, Wee Yao Koh, Cheng Nang Leong, Jeremy Chee Seong Tey, Ivan Weng Keong Tham, Kam Weng Fong
Chia Ching Lee, Gail Wan Ying Chua, Huili Zheng, Yu Yang Soon, Ling Li Foo, Anuradha Thiagarajan, Swee Peng Yap, Tian Rui Siow, Wee Loon Ng, Kevin Lee Min Chua, Connie Yip, Brendan Seng Hup Chia, Yan Yee Ng, Zubin Master, Poh Wee Tan, Yun Inn Tan, Yuh Fun Leong, Joan Faith Evacula Loria, Balamurugan Vellayappan, Wee Yao Koh, Cheng Nang Leong, Jeremy Chee Seong Tey, Ivan Weng Keong Tham, Kam Weng Fong
“Tube in tube” interlaminar endoscopic decompression for the treatment of lumbar spinal stenosis: Technique notes and preliminary clinical outcomes of case series
Shiqi Cao, Hongpeng Cui, Zhengcao Lu, Kai Zhu, Bensheng Fu, Wen Li, Jianjun Zhang, Yu Ding
Shiqi Cao, Hongpeng Cui, Zhengcao Lu, Kai Zhu, Bensheng Fu, Wen Li, Jianjun Zhang, Yu Ding
Clinical Case Report |
A CARE-compliant article: ipsilateral progressive idiopathic lipid keratopathy: A case report
Yilin Pang, Qin Zhang, Yongzhen Bao
Yilin Pang, Qin Zhang, Yongzhen Bao
The role of 18F-FDG PET/CT in management of paraneoplastic limbic encephalitis combined with small cell lung cancer: A case report
Helga Castagnoli, Carlo Manni, Francesca Marchesani, Gloria Rossi, Sara Fattori, Francesca Capoccetti
Helga Castagnoli, Carlo Manni, Francesca Marchesani, Gloria Rossi, Sara Fattori, Francesca Capoccetti
A case report of spontaneous coronary artery dissection complicated by stent fracture
Hanxiang Gao, Ye Hu, Qi Li, Suyu Yao, Zheng Zhang, Ming Bai
Hanxiang Gao, Ye Hu, Qi Li, Suyu Yao, Zheng Zhang, Ming Bai
Clinical characteristics and management of primary granulocytic sarcoma of the breast: A case report
Heng-yu Wu, Lei Liu, Lei Gu, Yong-hui Luo
Heng-yu Wu, Lei Liu, Lei Gu, Yong-hui Luo
Coexistence of colon adenocarcinoma, diffuse large B-cell lymphoma, and myelodysplastic syndrome: A case report
Wei Wang, Pei Li
Wei Wang, Pei Li
Ultrasound-guided percutaneous microwave ablation of parotid gland adenolymphoma: A case report
Mingyue Jin, Jili Fu, Jianbo Lu, Wanying Xu, Hui Chi, Xue Wang, Zhibin Cong
Mingyue Jin, Jili Fu, Jianbo Lu, Wanying Xu, Hui Chi, Xue Wang, Zhibin Cong
Multifocal head and neck amyloidosis as a diagnostic clue of systemic lupus erythematosus (SLE): A case report
Chih-Hao Chen, Chuan-Hung Sun
Chih-Hao Chen, Chuan-Hung Sun
Ectopic thyroid microfollicular adenoma in the lung: A case report
Wenjun Zhang, Hongsheng Zhang, Qiaoru Hou, Hongjun Hou, Dong Xu, Jie Liu, Lu Shi
Wenjun Zhang, Hongsheng Zhang, Qiaoru Hou, Hongjun Hou, Dong Xu, Jie Liu, Lu Shi
Multiple primary central nervous system lymphoma in the elderly: A case report
Guangyong Chen, Meiling Xu, Xuemei Wang, Yufei Gao, Chengyan He, Meiji Chang, Jinnan Zhang
Guangyong Chen, Meiling Xu, Xuemei Wang, Yufei Gao, Chengyan He, Meiji Chang, Jinnan Zhang
Facial nerve schwannoma mimicking chronic suppurative otitis media: A case report
Yueqiu Gao, Ziguang Shi, Chengkai Wang, Zhengzheng Yu
Yueqiu Gao, Ziguang Shi, Chengkai Wang, Zhengzheng Yu
An unusual case of Behcet disease with posterior scleritis: A case report
Chihiro Yanagida, Yoshihiko Usui, Jun-Ichi Sakai, Hiroshi Goto
Chihiro Yanagida, Yoshihiko Usui, Jun-Ichi Sakai, Hiroshi Goto
Low-dose methotrexate-induced vulvar edema: A case report
Guifeng Jia, Wei Chai, Zhiwei He, Xiaojing Liu, Yan Wen, Lifeng Cui, Fengyan Gong
Guifeng Jia, Wei Chai, Zhiwei He, Xiaojing Liu, Yan Wen, Lifeng Cui, Fengyan Gong
Congenital hepatic fibrosis and coexistent retinal macular degeneration: A case report
Dezhao Li, Junjie Qin, Shijuan Sun, Xu Li
Dezhao Li, Junjie Qin, Shijuan Sun, Xu Li
Lung abscess by Actinomyces odontolyticus and Parvimonas micra co-infection presenting as acute respiratory failure: A case report
Sang Suk Yun, Hyun Seop Cho, Manbong Heo, Jong Hwan Jeong, Hyang Rae Lee, Sunmi Ju, Ju-Young Kim, Jung Wan You, Yu Ji Cho, Yi Yeong Jeong, Ho Cheol Kim, Jong Deog Lee, Seung Jun Lee
Sang Suk Yun, Hyun Seop Cho, Manbong Heo, Jong Hwan Jeong, Hyang Rae Lee, Sunmi Ju, Ju-Young Kim, Jung Wan You, Yu Ji Cho, Yi Yeong Jeong, Ho Cheol Kim, Jong Deog Lee, Seung Jun Lee
Bleeding with negative coagulation screening test as initial presentation of chronic myelogenous leukemia managed by fresh frozen plasma: A case report
Yanzhi Wang, Lina Wang, Yaming Xi, Zijian Li
Yanzhi Wang, Lina Wang, Yaming Xi, Zijian Li
Next-generation sequencing specifies Angiostrongylus eosinophilic meningoencephalitis in infants: Two case reports
Mei Xie, Zhen Zhou, Suhua Guo, Zengqing Li, Hui Zhao, Jiusheng Deng
Mei Xie, Zhen Zhou, Suhua Guo, Zengqing Li, Hui Zhao, Jiusheng Deng
Surgical treatment of giant chordoma in the thoracic spine combining thoracoscopic and posterior spinal surgery: A case report
Shuzhong Liu, Xi Zhou, An Song, Zhen Huo, Siyuan Yao, Yipeng Wang, Yong Liu
Shuzhong Liu, Xi Zhou, An Song, Zhen Huo, Siyuan Yao, Yipeng Wang, Yong Liu
Parvovirus B19 infection presenting with neutropenia and thrombocytopenia: Three case reports
Hyoshim Shin, Sungwoo Park, Gyeong-Won Lee, Eun-Ha Koh, Hyun-Young Kim
Hyoshim Shin, Sungwoo Park, Gyeong-Won Lee, Eun-Ha Koh, Hyun-Young Kim
Down syndrome with primary thyroid diffuse large B-cell lymphoma and Hashimoto thyroiditis: A CARE compliant case report
Luyang Wei, Ning Zhao, Yalun Li, Xiaodan Zheng, Huaxin Zhang, Zhongtao Zhang
Luyang Wei, Ning Zhao, Yalun Li, Xiaodan Zheng, Huaxin Zhang, Zhongtao Zhang
Treatment of syncope in tongue cancer with palliative chemotherapy in the intensive care unit: A case report
Chongkai Fang, Liting Yang, Guangbi Zeng, Ruilin Huang, Wei Fang, Yao Chen, Jieshan Guan, Peng Li, Xuewu Huang, Lizhu Lin
Chongkai Fang, Liting Yang, Guangbi Zeng, Ruilin Huang, Wei Fang, Yao Chen, Jieshan Guan, Peng Li, Xuewu Huang, Lizhu Lin
Adenoid cystic carcinoma of the gastroesophageal junction: A case report
Chun-Hui Shou, Zhi-Jian Li, Wei-Li Yang, Welda E.H. Tjhoi, Zhi-Cheng Zhao, Ji-Ren Yu
Chun-Hui Shou, Zhi-Jian Li, Wei-Li Yang, Welda E.H. Tjhoi, Zhi-Cheng Zhao, Ji-Ren Yu
Fulminant bilateral acute retinal necrosis complicated with secondary herpes simplex type-1 viral encephalitis: A case report
Lingqi Ye, Xiansan Ding, Shanshan Shen, Jing Wang, Jimin Wu, Yanxing Chen
Lingqi Ye, Xiansan Ding, Shanshan Shen, Jing Wang, Jimin Wu, Yanxing Chen
Febrile convulsions during recovery after anesthesia in an infant with history of MMR vaccination: A case report
Hyung Gon Lee, Hong-Beom Bae, Jeong Il Choi, Taehee Pyeon, Sungmin Kim, Joungmin Kim
Hyung Gon Lee, Hong-Beom Bae, Jeong Il Choi, Taehee Pyeon, Sungmin Kim, Joungmin Kim
Clinical Trial/Experimental Study |
Fermented milk containing Lactobacillus paracasei and Glycyrrhiza glabra has a beneficial effect in patients with Helicobacter pylori infection: A randomized, double-blind, placebo-controlled study
Jin Young Yoon, Jae Myung Cha, Seong Soo Hong, Hyung Kyung Kim, Min Seob Kwak, Jung Won Jeon, Hyun Phil Shin
Jin Young Yoon, Jae Myung Cha, Seong Soo Hong, Hyung Kyung Kim, Min Seob Kwak, Jung Won Jeon, Hyun Phil Shin
Effects of dexmedetomidine vs sufentanil during percutaneous tracheostomy for traumatic brain injury patients: A prospective randomized controlled trial
Jian Gao, Limin Wei, Guangjun Xu, Chunguang Ren, Zongwang Zhang, Yanchao Liu
Jian Gao, Limin Wei, Guangjun Xu, Chunguang Ren, Zongwang Zhang, Yanchao Liu
Diagnostic Accuracy Study |
Endoscopy and magnetic resonance imaging-based prediction of ypT stage in patients with rectal cancer who received chemoradiotherapy: Results from a prospective study of 110 patients
Min Soo Cho, HonSoul Kim, Yoon Dae Han, Hyuk Hur, Byung Soh Min, Seung Hyuk Baik, Jae Hee Cheon, Joon Seok Lim, Kang Young Lee, Nam Kyu Kim
Min Soo Cho, HonSoul Kim, Yoon Dae Han, Hyuk Hur, Byung Soh Min, Seung Hyuk Baik, Jae Hee Cheon, Joon Seok Lim, Kang Young Lee, Nam Kyu Kim
Systematic Review and Meta-Analysis |
Vitamin D concentration and risk of Alzheimer disease: A meta-analysis of prospective cohort studies
Kui Yang, Jun Chen, Xiaoguang Li, Yongning Zhou
Kui Yang, Jun Chen, Xiaoguang Li, Yongning Zhou
Bibliometric analysis of oncolytic virus research, 2000 to 2018
Yidi Zou, Yong Luo, Jun Zhang, Ningshao Xia, Guowei Tan, Chenghao Huang
Yidi Zou, Yong Luo, Jun Zhang, Ningshao Xia, Guowei Tan, Chenghao Huang
Prevention, assessment, diagnosis and management of diabetic foot based on clinical practice guidelines: A systematic review
Alberto J. Pérez-Panero, María Ruiz-Muñoz, Antonio I. Cuesta-Vargas, Manuel Gónzalez-Sánchez
Alberto J. Pérez-Panero, María Ruiz-Muñoz, Antonio I. Cuesta-Vargas, Manuel Gónzalez-Sánchez
Association between miRNA polymorphisms and susceptibility to brain tumors: A meta-analysis
Fu’an Gao, Yuntao Zhu
Fu’an Gao, Yuntao Zhu
Robotic arm-assisted vs conventional unicompartmental knee arthroplasty: A meta-analysis of the effects on clinical outcomes
Fengjun Zhang, Hongcai Li, Zhaochen Ba, Chunguang Bo, Kai Li
Fengjun Zhang, Hongcai Li, Zhaochen Ba, Chunguang Bo, Kai Li
Study Protocol Clinical Trial |
Efficacy and safety of oral SOCG in treatment of major depressive disorder: A protocol for a phase II, randomized, double-blind, placebo controlled, parallel-groups, dose finding exploratory study
Ju Yeon Kim, Young Kyung Seo, Ji-Yoon Lee, Weechang Kang, Ik-Seung Chee, Kwang-Yeon Choi, In Chul Jung
Ju Yeon Kim, Young Kyung Seo, Ji-Yoon Lee, Weechang Kang, Ik-Seung Chee, Kwang-Yeon Choi, In Chul Jung
Acupuncture effect on digestion in critically ill postoperative oral and hypopharyngeal cancer patients: A protocol for double-blind randomized control trial
Eyal Ben-Arie, Pei-Yu Kao, Wen-Chao Ho, Yu Chen Lee
Eyal Ben-Arie, Pei-Yu Kao, Wen-Chao Ho, Yu Chen Lee
Multicenter study of lumbar discectomy with Barricaid annular closure device for prevention of lumbar disc reherniation in US patients: A historically controlled post-market study protocol
K. Brandon Strenge, Christian P. DiPaola, Larry E. Miller, Clint P. Hill, Robert G. Whitmore
K. Brandon Strenge, Christian P. DiPaola, Larry E. Miller, Clint P. Hill, Robert G. Whitmore
A study protocol of a single-center investigator-blinded randomized parallel group study to investigate the effect of an acclimatization visit on children's behavior during inhalational sedation in a United Arab Emirates pediatric dentistry postgraduate setting as measured by the levels of salivary Alpha Amylase and Cortisol
Manal Al Halabi, Iyad Hussein, Anas Salami, Rawan Awad, Najla Alderei, Ahtiq Wahab, Mawlood Kowash
Manal Al Halabi, Iyad Hussein, Anas Salami, Rawan Awad, Najla Alderei, Ahtiq Wahab, Mawlood Kowash
Study Protocol Systematic Review |
Efficacy of fasudil for the treatment of aneurysmal subarachnoid hemorrhage: A systematic review protocol of randomized controlled trial
Hao-yan Wang, Guang-fu Song, Hong-wei Yang, Xue-feng Chang, Ren-bo Shen, Fu-yi Yang
Hao-yan Wang, Guang-fu Song, Hong-wei Yang, Xue-feng Chang, Ren-bo Shen, Fu-yi Yang
Efficacy and safety of berberine in the treatment of type 2 diabetes with insulin resistance: Protocol for a systematic review
Yinshan Wang, Aihua Yan, Shanshan Li, Bei Liu, Huimin Li, Yong Yan
Yinshan Wang, Aihua Yan, Shanshan Li, Bei Liu, Huimin Li, Yong Yan
Physical activity and the risk of frailty among community-dwelling healthy older adults: A protocol for systematic review and meta-analysis
Bei Pan, Hongli Li, Yunhua Wang, Min Sun, Hui Cai, Jiancheng Wang
Bei Pan, Hongli Li, Yunhua Wang, Min Sun, Hui Cai, Jiancheng Wang
The effectiveness of exercise on cervical radiculopathy: A protocol for systematic review and meta-analysis
Long Liang, Xin Cui, Minshan Feng, Shuaiqi Zhou, Xunlu Yin, Feng He, Kai Sun, He Yin, Rong Xie, Dian Zhang, You Zhou, Yue Wu, Guihong Tan, Zhengdong Wang, Xingyu Wang, Jianhua Zhang, Liguo Zhu, Jie Yu, Xu Wei
Long Liang, Xin Cui, Minshan Feng, Shuaiqi Zhou, Xunlu Yin, Feng He, Kai Sun, He Yin, Rong Xie, Dian Zhang, You Zhou, Yue Wu, Guihong Tan, Zhengdong Wang, Xingyu Wang, Jianhua Zhang, Liguo Zhu, Jie Yu, Xu Wei
Protocol for systematic reviews of school-based food and nutrition education intervention for adolescent health promotion: Evidence mapping and syntheses
Gidyenne Christine Bandeira Silva de Medeiros, Kesley Pablo Morais de Azevedo, Daniel Ángel Garcia, Victor Hugo de Oliveira Segundo, Ádala Nayana de Sousa Mata, Karla Silveria Dias Pinheiro de Siqueira, Anny Karoliny Pinheiro Fernandes, Raquel Praxedes dos Santos, Débora Danielly Barros de Brito Trindade, Clélia de Oliveira Lyra, Grasiela Piuvezam
Gidyenne Christine Bandeira Silva de Medeiros, Kesley Pablo Morais de Azevedo, Daniel Ángel Garcia, Victor Hugo de Oliveira Segundo, Ádala Nayana de Sousa Mata, Karla Silveria Dias Pinheiro de Siqueira, Anny Karoliny Pinheiro Fernandes, Raquel Praxedes dos Santos, Débora Danielly Barros de Brito Trindade, Clélia de Oliveira Lyra, Grasiela Piuvezam
Chinese Herbal Medicine Versus Placebo for the Treatment Of Chronic Obstructive Pulmonary Disease: A Protocol of Systematic Review and Meta-analysis
Chan Xiong, Yu Li, Yan Zeng, Hua Wei, Guang-tong Zhuang, Lin Li, Li-hong Zhao, Chen-yi Li, Er-qi Qin, Juan-juan Fu
Chan Xiong, Yu Li, Yan Zeng, Hua Wei, Guang-tong Zhuang, Lin Li, Li-hong Zhao, Chen-yi Li, Er-qi Qin, Juan-juan Fu
Efficacy and safety of acupuncture therapy for chronic atrophic gastritis: A meta-analysis and trial sequential analysis protocol
Yuan Li, Yili Zhang, Han Meng, Mengting Liao, Zeqi Su, Mengyin Zhai, Lingling Jiang, Ping Li, Xia Ding
Yuan Li, Yili Zhang, Han Meng, Mengting Liao, Zeqi Su, Mengyin Zhai, Lingling Jiang, Ping Li, Xia Ding
Adjuvant treatment with Xiaoqinglong formula for bronchial asthma: Protocol of systematic review and meta-analysis
Long Wang, Xiuli Zheng, Yi Hui, Baojia Wang, Yu Yang, Xianrong Feng, Tianyao Zhang, Li Ma, Xiaobo Zhang
Long Wang, Xiuli Zheng, Yi Hui, Baojia Wang, Yu Yang, Xianrong Feng, Tianyao Zhang, Li Ma, Xiaobo Zhang
Delta neutrophil index as a predictor of disease severity, surgical outcomes, and mortality rates in gastrointestinal diseases: Rationale for a meta-analysis of diagnostic test accuracy
Jae Ho Choi, Chang Seok Bang, Jae Jun Lee, Gwang Ho Baik
Jae Ho Choi, Chang Seok Bang, Jae Jun Lee, Gwang Ho Baik
Neoadjuvant chemotherapy before radical prostatectomy for locally advanced prostate cancer: Protocol for a systematic review and meta-analysis
Tianhai Lin, Xiong Yang, Lina Gong, Hang Xu, Shi Qiu, Ruichao Yu, Sheng Sun, Liangren Liu, Peng Zhang, Ping Han, Jingqiu Cheng, Lu Yang, Qiang Wei
Tianhai Lin, Xiong Yang, Lina Gong, Hang Xu, Shi Qiu, Ruichao Yu, Sheng Sun, Liangren Liu, Peng Zhang, Ping Han, Jingqiu Cheng, Lu Yang, Qiang Wei
Case Report |
Ultrasound appearance of intravenous leiomyomatosis: A case report
Zhitong Ge, Yahong Wang, Zhenhong Qi, Qing Zhang, Jin Jin, Jianchu Li
Zhitong Ge, Yahong Wang, Zhenhong Qi, Qing Zhang, Jin Jin, Jianchu Li
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