IJMS, Vol. 20, Pages 4443: Evans Blue Reduces Neuropathic Pain Behavior by Inhibiting Spinal ATP Release International Journal of Molecular Sciences doi: 10.3390/ijms20184443 Authors: Yin Hong Phạm Shin Gwon Kwon Shin Shin Lee Lee Kim Upon peripheral nerve injury, vesicular ATP is released from damaged primary afferent neurons. This extracellular ATP subsequently activates purinergic receptors of the spinal cord, which play a critical role in...
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4442: Genetic Dissection of Seed Storability and Validation of Candidate Gene Associated with Antioxidant Capability in Rice (Oryza sativa L.) International Journal of Molecular Sciences doi: 10.3390/ijms20184442 Authors: Yuan Fan Xia Ding Tian Sun He Yu Seed storability, defined as the ability to remain alive during storage, is an important agronomic and physiological characteristic, but the underlying genetic mechanism remains largely...
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4444: Nonalcoholic Fatty Liver Disease (NAFLD), But not Its Susceptibility Gene Variants, Influences the Decrease of Kidney Function in Overweight/Obese Children International Journal of Molecular Sciences doi: 10.3390/ijms20184444 Authors: Di Costanzo Pacifico D’Erasmo Polito Martino Perla Iezzi Chiesa Arca : Nonalcoholic fatty liver disease (NAFLD) is associated with an increased risk of kidney disease in adults and children. However,...
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4440: The Insulin/IGF System in Mammalian Sexual Development and Reproduction International Journal of Molecular Sciences doi: 10.3390/ijms20184440 Authors: Neirijnck Papaioannou Nef Persistent research over the past few decades has clearly established that the insulin-like family of growth factors, which is composed of insulin and insulin-like growth factors 1 (IGF1) and 2 (IGF2), plays essential roles in sexual development and reproduction of both males...
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4439: Mitochondrial Peptide Humanin Protects Silver Nanoparticles-Induced Neurotoxicity in Human Neuroblastoma Cancer Cells (SH-SY5Y) International Journal of Molecular Sciences doi: 10.3390/ijms20184439 Authors: Gurunathan Jeyaraj Kang Kim The extensive usage of silver nanoparticles (AgNPs) as medical products such as antimicrobial and anticancer agents has raised concerns about their harmful effects on human beings. AgNPs can potentially induce oxidative...
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4441: Biophysical Insight on the Membrane Insertion of an Arginine-Rich Cell-Penetrating Peptide International Journal of Molecular Sciences doi: 10.3390/ijms20184441 Authors: Marie-Lise Jobin Lydie Vamparys Romain Deniau Axelle Grélard Cameron D. Mackereth Patrick F.J. Fuchs Isabel D. Alves Cell-penetrating peptides (CPPs) are short peptides that can translocate and transport cargoes into the intracellular milieu by crossing biological membranes....
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4437: OsWRKY5 Promotes Rice Leaf Senescence via Senescence-Associated NAC and Abscisic Acid Biosynthesis Pathway International Journal of Molecular Sciences doi: 10.3390/ijms20184437 Authors: Kim Kang Kim An Paek he onset of leaf senescence is triggered by external cues and internal factors such as phytohormones and signaling pathways involving transcription factors (TFs). Abscisic acid (ABA) strongly induces senescence and endogenous ABA levels...
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4438: Phenotypic Plasticity of Fibroblasts during Mammary Carcinoma Development
IJMS, Vol. 20, Pages 4438: Phenotypic Plasticity of Fibroblasts during Mammary Carcinoma Development International Journal of Molecular Sciences doi: 10.3390/ijms20184438 Authors: Elwakeel Brüggemann Fink Schulz Schmid Savai Brüne Zarnack Weigert : Cancer-associated fibroblasts (CAFs) in the tumor microenvironment contribute to all stages of tumorigenesis and are usually considered to be tumor-promoting cells. CAFs show a remarkable degree of heterogeneity,...
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4435: Overexpression of WAX INDUCER1/SHINE1 Gene Enhances Wax Accumulation under Osmotic Stress and Oil Synthesis in Brassica napus International Journal of Molecular Sciences doi: 10.3390/ijms20184435 Authors: Ning Liu Jie Chen Tiehu Wang Qing Li Pengpeng Cui Chengxi Jia Yueyun Hong WAX INDUCER1/SHINE1 (WIN1) belongs to the AP2/EREBP transcription factor family and plays an important role in wax and cutin accumulation in plants. Here we show that...
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4436: Different Synergy in Amyloids and Biologically Active Forms of Proteins International Journal of Molecular Sciences doi: 10.3390/ijms20184436 Authors: Piotr Fabian Katarzyna Stapor Mateusz Banach Magdalena Ptak-Kaczor Leszek Konieczny Irena Roterman Protein structure is the result of the high synergy of all amino acids present in the protein. This synergy is the result of an overall strategy for adapting a specific protein structure. It is a...
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4434: In Search for the Membrane Regulators of Archaea International Journal of Molecular Sciences doi: 10.3390/ijms20184434 Authors: Marta Salvador-Castell Maxime Tourte Philippe M. Oger Membrane regulators such as sterols and hopanoids play a major role in the physiological and physicochemical adaptation of the different plasmic membranes in Eukarya and Bacteria. They are key to the functionalization and the spatialization of the membrane, and therefore indispensable...
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4432: The Role of Lysosomes in a Broad Disease-Modifying Approach Evaluated across Transgenic Mouse Models of Alzheimer’s Disease and Parkinson’s Disease and Models of Mild Cognitive Impairment International Journal of Molecular Sciences doi: 10.3390/ijms20184432 Authors: Jeannie Hwang Candice M. Estick Uzoma S. Ikonne David Butler Morgan C. Pait Lyndsie H. Elliott Sarah Ruiz Kaitlan Smith Katherine M. Rentschler Cary Mundell Michael F. Almeida...
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4430: TRPM6 N-Terminal CaM- and S100A1-Binding Domains International Journal of Molecular Sciences doi: 10.3390/ijms20184430 Authors: Monika Zouharova Petr Herman Kateřina Hofbauerová Jiri Vondrasek Kristyna Bousova Transient receptor potential (TRPs) channels are crucial downstream targets of calcium signalling cascades. They can be modulated either by calcium itself and/or by calcium-binding proteins (CBPs). Intracellular messengers usually interact...
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4431: Involvement of Novel Adipokines, Chemerin, Visfatin, Resistin and Apelin in Reproductive Functions in Normal and Pathological Conditions in Humans and Animal Models International Journal of Molecular Sciences doi: 10.3390/ijms20184431 Authors: Anthony Estienne Alice Bongrani Maxime Reverchon Christelle Ramé Pierre-Henri Ducluzeau Pascal Froment Joëlle Dupont It is well known that adipokines are endocrine factors that are mainly secreted by...
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4429: IBR5 Regulates Leaf Serrations Development via Modulation of the Expression of PIN1 International Journal of Molecular Sciences doi: 10.3390/ijms20184429 Authors: Xiuzhen Kong Guoqiang Huang Yali Xiong Chunyan Zhao Jun Wang Xiaoyun Song Jitender Giri Kaijing Zuo Biodiversity in plant shape is mainly attributable to the diversity of leaf shape, which is largely determined by the transient morphogenetic activity of the leaf margin that creates...
Mon Sep 09, 2019 03:00
IJMS, Vol. 20, Pages 4428: A DAO1-Mediated Circuit Controls Auxin and Jasmonate Crosstalk Robustness during Adventitious Root Initiation in Arabidopsis International Journal of Molecular Sciences doi: 10.3390/ijms20184428 Authors: Abdellah Lakehal Asma Dob Ondřej Novák Catherine Bellini Adventitious rooting is a post-embryonic developmental program governed by a multitude of endogenous and environmental cues. Auxin, along with other phytohormones, integrates and translates these...
Mon Sep 09, 2019 03:00
JCM, Vol. 8, Pages 1423: Assessment of Global Longitudinal and Circumferential Strain Using Computed Tomography Feature Tracking: Intra-Individual Comparison with CMR Feature Tracking and Myocardial Tagging in Patients with Severe Aortic Stenosis Journal of Clinical Medicine doi: 10.3390/jcm8091423 Authors: Emilija Miskinyte Paulius Bucius Jennifer Erley Seyedeh Mahsa Zamani Radu Tanacli Christian Stehning Christopher Schneeweis Tomas Lapinskas Burkert Pieske Volkmar...
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JCM, Vol. 8, Pages 1422: The Evolution of the Role of External Ventricular Drainage in Traumatic Brain Injury Journal of Clinical Medicine doi: 10.3390/jcm8091422 Authors: Charlene Y. C. Chau Claudia L. Craven Andres M. Rubiano Hadie Adams Selma Tülü Marek Czosnyka Franco Servadei Ari Ercole Peter J. Hutchinson Angelos G. Kolias External ventricular drains (EVDs) are commonly used in neurosurgery in different conditions but frequently in the management of traumatic...
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JCM, Vol. 8, Pages 1420: Drosophila melanogaster Mutated in its GBA1b Ortholog Recapitulates Neuronopathic Gaucher Disease Journal of Clinical Medicine doi: 10.3390/jcm8091420 Authors: Cabasso Paul Dorot Maor Krivoruk Pasmanik-Chor Mirzaian Ferraz Aerts Horowitz Gaucher disease (GD) results from mutations in the GBA1 gene, which encodes lysosomal glucocerebrosidase (GCase). The large number of mutations known to date in the gene lead to a heterogeneous...
Mon Sep 09, 2019 03:00
JCM, Vol. 8, Pages 1421: The Effect of Preservation Temperature on Liver, Kidney, and Pancreas Tissue ATP in Animal and Preclinical Human Models Journal of Clinical Medicine doi: 10.3390/jcm8091421 Authors: Bellini Yiu Nozdrin Papalois The recent advances in machine perfusion (MP) technology involve settings ranging between hypothermic, subnormothermic, and normothermic temperatures. Tissue level adenosine triphosphate (ATP) is a long-established marker of viability and...
Mon Sep 09, 2019 03:00
JCM, Vol. 8, Pages 1419: Deep Learning-Based Stroke Volume Estimation Outperforms Conventional Arterial Contour Method in Patients with Hemodynamic Instability Journal of Clinical Medicine doi: 10.3390/jcm8091419 Authors: Young-Jin Moon Hyun S. Moon Dong-Sub Kim Jae-Man Kim Joon-Kyu Lee Woo-Hyun Shim Sung-Hoon Kim Gyu-Sam Hwang Jae-Soon Choi Although the stroke volume (SV) estimation by arterial blood pressure has been widely used in clinical practice, its accuracy...
Mon Sep 09, 2019 03:00
JCM, Vol. 8, Pages 1418: MRI-Tracking of Dental Pulp Stem Cells In Vitro and In Vivo Using Dextran-Coated Superparamagnetic Iron Oxide Nanoparticles Journal of Clinical Medicine doi: 10.3390/jcm8091418 Authors: Shahrokh Zare Davood Mehrabani Reza Jalli Mahdi Saeedi Moghadam Navid Manafi Golshid Mehrabani Iman Jamhiri Samad Ahadian The aim of this study was to track dental pulp stem cells (DPSCs) labeled with dextran-coated superparamagnetic iron oxide nanoparticles...
Mon Sep 09, 2019 03:00
JoF, Vol. 5, Pages 85: Sweet Relief: Determining the Antimicrobial Activity of Medical Grade Honey Against Vaginal Isolates of Candida albicans Journal of Fungi doi: 10.3390/jof5030085 Authors: Renée Hermanns Niels A.J. Cremers John P. Leeming Esther T. van der Werf Recurrent vulvovaginal candidiasis (RVVC) is predicted to increase to almost 158 million cases annually by 2030. Extensive self-diagnosis and easily accessible over-the-counter (OTC) fungistatic drugs contribute...
Mon Sep 09, 2019 03:00
Life, Vol. 9, Pages 72: Characterizing Interstellar Medium, Planetary Surface and Deep Environments by Spectroscopic Techniques Using Unique Simulation Chambers at Centro de Astrobiologia (CAB) Life doi: 10.3390/life9030072 Authors: Eva Mateo-Marti Olga Prieto-Ballesteros Guillermo Muñoz Caro Cristobal González-Díaz Victoria Muñoz-Iglesias Santos Gálvez-Martínez At present, the study of diverse habitable environments of astrobiological interest has become a major challenge....
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Medicina, Vol. 55, Pages 580: Combined Pulmonary Fibrosis and Emphysema: Pulmonary Function Testing and a Pathophysiology Perspective Medicina doi: 10.3390/medicina55090580 Authors: Diana E. Amariei Neal Dodia Janaki Deepak Stella E. Hines Jeffrey R. Galvin Sergei P. Atamas Nevins W. Todd Combined pulmonary fibrosis and emphysema (CPFE) has been increasingly recognized over the past 10–15 years as a clinical entity characterized by rather severe imaging and...
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Medicina, Vol. 55, Pages 579: Hepatoprotective and Renoprotective Properties of Lovastatin-Loaded Ginger and Garlic Oil Nanoemulsomes: Insights into Serum Biological Parameters Medicina doi: 10.3390/medicina55090579 Authors: Faran Asghar Khalid Khan Asif Khalid Gohar Hussain Background and Objectives: Dyslipidemia is gaining much attention among healthcare professionals because of its high association with the malfunctioning of a number of normal physiological...
Mon Sep 09, 2019 03:00
Medicina, Vol. 55, Pages 578: The Skin in Celiac Disease Patients: The Other Side of the Coin Medicina doi: 10.3390/medicina55090578 Authors: Ludovico Abenavoli Stefano Dastoli Luigi Bennardo Luigi Boccuto Maria Passante Martina Silvestri Ilaria Proietti Concetta Potenza Francesco Luzza Steven Paul Nisticò Celiac disease (CD) is an autoimmune enteropathy that primarily affects the small intestine and is characterized by atrophy of intestinal villi. The manifestations...
Mon Sep 09, 2019 03:00
Medicines, Vol. 6, Pages 94: Functional Foods and Bioactive Compounds: A Review of Its Possible Role on Weight Management and Obesity’s Metabolic Consequences Medicines doi: 10.3390/medicines6030094 Authors: Melina Konstantinidi Antonios E. Koutelidakis Background: Weight management and obesity prevention is a basic aim of health organizations in order to decrease the prevalence of various metabolic disorders. The aim of the present review article was the evaluation of the possible...
Mon Sep 09, 2019 03:00
Microorganisms, Vol. 7, Pages 336: The Intestine of Drosophila melanogaster: An Emerging Versatile Model System to Study Intestinal Epithelial Homeostasis and Host-Microbial Interactions in Humans Microorganisms doi: 10.3390/microorganisms7090336 Authors: Florence Capo Alexa Wilson Francesca Di Cara In all metazoans, the intestinal tract is an essential organ to integrate nutritional signaling, hormonal cues and immunometabolic networks. The dysregulation of intestinal epithelium...
Mon Sep 09, 2019 03:00
Microorganisms, Vol. 7, Pages 334: Influenza A Virus Detected in Native Bivalves in Waterfowl Habitat of the Delmarva Peninsula, USA Microorganisms doi: 10.3390/microorganisms7090334 Authors: Christine L. Densmore Deborah D. Iwanowicz Shawn M. McLaughlin Christopher A. Ottinger Jason E. Spires Luke R. Iwanowicz We evaluated the prevalence of influenza A virus (IAV) in different species of bivalves inhabiting natural water bodies in waterfowl habitat along the Delmarva...
Mon Sep 09, 2019 03:00
Microorganisms, Vol. 7, Pages 335: A Glimpse into Genetic Diversity and Symbiont Interaction Patterns in Lichen Communities from Areas with Different Disturbance Histories in Białowieża Forest, Poland Microorganisms doi: 10.3390/microorganisms7090335 Authors: Garima Singh Martin Kukwa Francesco Dal Grande Anna Łubek Jürgen Otte Imke Schmitt Anthropogenic disturbances can have strong impacts on lichen communities, as well as on individual species of lichenized fungi. Traditionally,...
Mon Sep 09, 2019 03:00
Molbank, Vol. 2019, Article M1079: 2-(3,4-Dimethoxyphenyl)-N-(4-methoxyphenyl)-1-propyl-1H-benzo[d]imidazole-5-carboxamide Molbank doi: 10.3390/M1079 Authors: Prakash Bhaskar Vasantha Kumar Suresha Kumara Tholappanavara Hanumanthappa Sowmya Haliwana Banakara Vijaykumar 2-(3,4-Dimethoxyphenyl)-N-(4-methoxyphenyl)-1-propyl-1H-benzo[d]imidazole-5-carboxamide was synthesized by the ‘one-pot’ reductive cyclization of N-(4-methoxyphenyl)-3-nitro-4-(propylamino)benzamide...
Mon Sep 09, 2019 03:00
Molecules, Vol. 24, Pages 3292: Antimicrobial Carvacrol Incorporated in Flaxseed Gum-Sodium Alginate Active Films to Improve the Quality Attributes of Chinese Sea bass (Lateolabrax maculatus) during Cold Storage Molecules doi: 10.3390/molecules24183292 Authors: Shiyuan Fang Qianqian Zhou Yan Hu Feng Liu Jun Mei Jing Xie The objective of this research was to explore the antimicrobial activity and mechanism of carvacrol against Vibrio Parahemolyticus, Shewanella putrefaciens,...
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Molecules, Vol. 24, Pages 3287: Site Selective Antibody-Oligonucleotide Conjugation via Microbial Transglutaminase Molecules doi: 10.3390/molecules24183287 Authors: Ian J. Huggins Carlos A. Medina Aaron D. Springer Arjen van den Berg Satish Jadhav Xianshu Cui Steven F. Dowdy Nucleic Acid Therapeutics (NATs), including siRNAs and AntiSense Oligonucleotides (ASOs), have great potential to drug the undruggable genome. Targeting siRNAs and ASOs to specific cell types of...
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Molecules, Vol. 24, Pages 3290: Palladium Supported on Porous Chitosan–Graphene Oxide Aerogels as Highly Efficient Catalysts for Hydrogen Generation from Formate Molecules doi: 10.3390/molecules24183290 Authors: Aicha Anouar Nadia Katir Abdelkrim El Kadib Ana Primo Hermenegildo García Adsorption of Pd(NH3)42+ in preformed chitosan–graphene oxide (CS-GO) beads and their subsequent reduction with NaBH4 afford well-dispersed, high dispersion (~21%) of uniformly sized...
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Molecules, Vol. 24, Pages 3291: Hyaluronic Acid–Decorated Liposomes as Innovative Targeted Delivery System for Lung Fibrotic Cells Molecules doi: 10.3390/molecules24183291 Authors: Laura Pandolfi Vanessa Frangipane Claudia Bocca Alessandro Marengo Erika Tarro Genta Sara Bozzini Monica Morosini Maura D’Amato Simone Vitulo Manuela Monti Giuditta Comolli Maria Teresa Scupoli Elias Fattal Silvia Arpicco Federica Meloni Collagen Tissue Disease–associated...
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Molecules, Vol. 24, Pages 3288: Enlargement of a Modular System—Synthesis and Characterization of an s-Triazine-Based Carboxylic Acid Ester Bearing a Galactopyranosyl Moiety and an Enormous Boron Load Molecules doi: 10.3390/molecules24183288 Authors: Martin Kellert Peter Lönnecke Bernd Riedl Johannes Koebberling Evamarie Hey-Hawkins The amount of boron accumulated in tumor tissue plays an important role regarding the success of the boron neutron capture therapy (BNCT). In...
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Molecules, Vol. 24, Pages 3289: Combined Analysis of Primary Metabolites and Phenolic Compounds to Authenticate Commercial Monovarietal Peach Purees and Pear Juices Molecules doi: 10.3390/molecules24183289 Authors: Antoni Delpino-Rius Jordi Eras Ferran Gatius Mercè Balcells Ramon Canela-Garayoa Here we authenticated single-varietal peach purees and pear juices on the basis of primary metabolite and phenolic compound analysis by Proton Nuclear Magnetic Resonance (1H-NMR) and...
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Molecules, Vol. 24, Pages 3285: Synthesis of Pluri-Functional Amine Hardeners from Bio-Based Aromatic Aldehydes for Epoxy Amine Thermosets Molecules doi: 10.3390/molecules24183285 Authors: Mora Tayouo Boutevin David Caillol Most of the current amine hardeners are petro-sourced and only a few studies have focused on the research of bio-based substitutes. Hence, in an eco-friendly context, our team proposed the design of bio-based amine monomers with aromatic structures....
Mon Sep 09, 2019 03:00
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