Publication date: Available online 31 August 2019Source: Academic RadiologyAuthor(s): Marta E. Heilbrun, Brad Poss, Luca Boi, Yoshimi Anzai, Nan Hu, Robert S. KaplanRationale and ObjectivesTo quantify the costs and work of diagnostic radiology (DR) residents using the radiology key performance indicator turn-around time (TAT) as the outcome measure.Materials and MethodsIn an Institutional Review Board-approved study, the annual cost of a DR resident was determined using salary, benefits, and a cost...
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Publication date: Available online 31 August 2019Source: Clinical ImagingAuthor(s): Julie Sogani, Bibb Allen, Keith Dreyer, Geraldine McGintyAbstractThe rapid development of artificial intelligence (AI) has led to its widespread use in multiple industries, including healthcare. AI has the potential to be a transformative technology that will significantly impact patient care. Particularly, AI has a promising role in radiology, in which computers are indispensable and new technological advances are...
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Abstract Purpose The role of 68Ga-PSMA PET/CT in the staging of prostate cancer is well known. PSMA is also overexpressed in the neovasculature of other tumours including renal cell carcinoma (RCC), suggesting there may be a role for the use of 68Ga-PSMA PET/CT. Thus far, there has been limited literature documenting the use of 68Ga-PSMA PET/CT in the investigation and management decisions of RCC. ...
Abstract Purpose Enlarged perivascular spaces in the centrum semiovale (CSO-EPVS) have been linked to cerebral amyloid angiopathy (CAA). To get insight into the underlying mechanisms of this association, we investigated the relationship between amyloid-β deposition assessed by 18F-florbetapir PET and CSO-EPVS in patients with acute intracerebral hemorrhage (ICH). ...
Abstract Background Recently, semiquantitative time-intensity curve (TIC) analysis based on DCE-MRI and apparent diffusion coefficient (ADC) value-based diffusion-weighted imaging (DWI) were used to improve the diagnostic efficiency when diagnosing parotid tumors (PTs). However, quantitative DCE-MRI biomarkers have not been emphasized previously. Purpose ...
Abstract Purpose Reported outcomes of patients with intra-hepatic cholangiocarcinoma (IH-CCA) treated with radioembolization are highly variable, which indicates differences in included patients’ characteristics and/or procedure-related variables. This study aimed to identify patient- and treatment-related variables predictive for radioembolization outcome. Methods...
Abstract Purpose An imaging-based stratification tool is needed to identify melanoma patients who will benefit from anti Programmed Death-1 antibody (anti-PD1). We aimed at identifying biomarkers for survival and response evaluated in lymphoid tissue metabolism in spleen and bone marrow before initiation of therapy. Methods This retrospective...
Abstract Purpose To evaluate the prognostic value of volumetric parameters calculated from 68Ga-1,4,7,10-tetraazacyclododecane-1, 4, 7, 10-tetraacetic acid (DOTA)-Thr3-octreotate (68Ga-DOTATATE) positron emission tomography/computed tomography (PET/CT) in patients with well-differentiated neuroendocrine tumor (WD-NET). Methods Ninety-two patients...
Abstract The EANM/SNMMI 2019 guidelines for radionuclide imaging of phaeochromocytoma and paraganglioma (PPGL) describe the current experts’ views on molecular imaging in the era of precision medicine, and contain all of the information needed by nuclear physicians for performing, interpreting, and reporting the results of imaging investigations. This editorial, from a clinician’s perspective, describes the first-choice radiopharmaceutical for a particular clinical setting as...
Abstract Purpose Amyloid (Aβ) brain deposition can occur in cognitively normal individuals and is associated with cortical volume abnormalities. Aβ-related volume changes are inconsistent across studies. Since volume is composed of surface area and thickness, the relative contribution of Aβ deposition on each of these metrics remains to be understood in cognitively normal individuals. ...
Abstract Purpose The primary aim of the present study was to evaluate if PET/MR induced management changes versus standard of care imaging (SCI) in treated colorectal cancer patients. The secondary aim was to assess the staging performance of PET/MR and of SCI versus the final oncologic stage. Methods Treated CRC patients who underwent PET/MR...
Abstract Purposes Whether low-calorie sweeteners (LCS), such as sucralose and acesulfame K, can alter glucose metabolism is uncertain, particularly given the inconsistent observations relating to insulin resistance in recent human trials. We hypothesized that these discrepancies are accounted for by the surrogate tools used to evaluate insulin resistance and that PET 18FDG, given its capacity to quantify insulin sensitivity in individual...
Abstract Purpose The purpose of this study was to investigate the effects of ageing, sex and body mass index (BMI) on translocator protein (TSPO) availability in healthy subjects using positron emission tomography (PET) and the radioligand [11C]PBR28. Methods [11C]PBR28 data from 140 healthy volunteers (72 males and 68 females; N = 78 with HAB...
Abstract Purpose So far, there have been very few studies which provide a direct comparison between MRI and PSMA-ligand PET/CT for the detection of recurrent prostate cancer (rPC). This present study therefore aims to provide further clinical data in order to resolve this urgent clinical question, and thereby strengthen clinical recommendations. Methods ...
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Publication date: 15 November 2019Source: NeuroImage, Volume 202Author(s): Samuel Planton, Valérie Chanoine, Julien Sein, Jean-Luc Anton, Bruno Nazarian, Christophe Pallier, Chotiga PattamadilokAbstractThe left ventral occipitotemporal cortex (vOT) is considered the key area of the visuo-orthographic system. However, some studies reported that the area is also involved in speech processing tasks, especially those that require activation of orthographic knowledge. These findings suggest the existence...
Publication date: 15 November 2019Source: NeuroImage, Volume 202Author(s): Lars Riecke, Sophia Snipes, Sander van Bree, Amanda Kaas, Lars HausfeldAbstractViewing a speaker’s lip movements can improve the brain’s ability to ‘track’ the amplitude envelope of the auditory speech signal and facilitate intelligibility. Whether such neurobehavioral benefits can also arise from tactually sensing the speech envelope on the skin is unclear. We hypothesized that tactile speech envelopes can improve neural...
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Abstract Purpose Flow diverter (FD) devices show severe shortening during deployment in dependency of the vessel geometry. Valid information regarding the geometry of the targeted vessel is therefore mandatory for correct device selection, and to avoid complications. But the geometry of diseased tortuous intracranial vessels cannot be measured accurately with standard methods. The goal of this study is to prove the accuracy of a novel...
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Abstract Background Ultrasound (US) has been used in the adult trauma population with reported moderate to high sensitivities, but data are scarce in the pediatric trauma population. Objective The purpose of this study was to specifically examine the sensitivity and specificity of one lung US methodology (single-point anterior exam) in the pediatric trauma...
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Publication date: Available online 31 August 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Qingyang Liu, Junhui Hu, Igor V. Minin, Oleg V. MininAbstractThe manipulation of motile and still single cells with the simultaneous features of selective trapping, 3-D path free transport, position-controllable release and little heat damage has been a significant challenge. We developed an ultrasonic method for capturing motile and still single cells with the aforementioned features in a droplet....
Publication date: Available online 30 August 2019Source: Ultrasound in Medicine & BiologyAuthor(s): David H. Ballard
Publication date: Available online 30 August 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Sarah Cleve, Claude Inserra, Paul PrenticeAbstractThe initial response of microbubbles flowing through a 500-μm polycarbonate capillary to a burst of 200-kHz focused ultrasound, at peak-negative pressure amplitudes from 0.7–1.5 MPa, was investigated with dual-perspective high-speed imaging. Directed jetting through the acoustic focus is demonstrated according to the pressure gradients acting across...
Publication date: October 2019Source: Ultrasound in Medicine & Biology, Volume 45, Issue 10Author(s):
Publication date: October 2019Source: Ultrasound in Medicine & Biology, Volume 45, Issue 10Author(s):
Publication date: October 2019Source: Ultrasound in Medicine & Biology, Volume 45, Issue 10Author(s):
Publication date: October 2019Source: Ultrasound in Medicine & Biology, Volume 45, Issue 10Author(s):
Publication date: Available online 30 August 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Hai-Mei Lun, Shang-Yong Zhu, Qiao Hu, Yao-Li Liu, Li-si WeiAbstractTo investigate the feasibility of ultrasonography in detecting the oropharynx movement during deep breathing and to quantitatively analyze oropharynx airway lumen changes during deep breathing. The motions of oropharynx were monitored, and sonographic measurements of airway lumen were obtained during deep breathing in 448 healthy...
Effect of Ultrasound on the Vasculature and Extravasation of Nanoscale Particles Imaged in Real Time
Publication date: Available online 30 August 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Petros T. Yemane, Andreas K.O. Åslund, Sofie Snipstad, Astrid Bjørkøy, Kristin Grendstad, Sigrid Berg, Yrr Mørch, Sverre H. Torp, Rune Hansen, Catharina de Lange DaviesAbstractUltrasound and microbubbles have been found to improve the delivery of drugs and nanoparticles to tumor tissue. To obtain new knowledge on the influence of vascular parameters on extravasation and to elucidate the effect...
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