IJMS, Vol. 20, Pages 5984: Molecular Imaging of Diabetic Foot Infections: New Tools for Old Questions International Journal of Molecular Sciences doi: 10.3390/ijms20235984 Authors: Camilo A. Ruiz-Bedoya Oren Gordon Filipa Mota Sudhanshu Abhishek Elizabeth W. Tucker Alvaro A. Ordonez Sanjay K. Jain Diabetic foot infections (DFIs) are a common, complex, and costly medical problem with increasing prevalence. Diagnosing DFIs is a clinical challenge due to the poor specificity...
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IJMS, Vol. 20, Pages 5986: Treatment of Metastatic or High-Risk Solid Cancer Patients by Targeting the Immune System and/or Tumor Burden: Six Cases Reports International Journal of Molecular Sciences doi: 10.3390/ijms20235986 Authors: Andrea Nicolini Paola Ferrari Riccardo Morganti Angelo Carpi This article summarizes the histories of six patients with different solid tumors treated with a new strategy based on tumor burden reduction and immune evasion as potential targets....
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IJMS, Vol. 20, Pages 5982: Parasympathetic Effect Induces Cell Cycle Activation in Upper Limbs of Paraplegic Patients with Spinal Cord Injury International Journal of Molecular Sciences doi: 10.3390/ijms20235982 Authors: Ahreum Baek Ji Cheol Shin Min-Young Lee Sung Hoon Kim Jiyong Kim Sung-Rae Cho The present study aimed to investigate gene expression changes related to cell cycle activation in patients with spinal cord injury (SCI) and to further evaluate the difference...
Wed Nov 27, 2019 02:00
IJMS, Vol. 20, Pages 5980: Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability International Journal of Molecular Sciences doi: 10.3390/ijms20235980 Authors: Raineri Fasoli Campagnari Gotte Menegazzi Melanoma is a lethal tumor because of its severe metastatic potential, and serine/threonine-protein kinase B-raf inhibitors (BRAFi) are used in patients harboring BRAF-mutation....
Wed Nov 27, 2019 02:00
IJMS, Vol. 20, Pages 5981: Circulating CRP Levels Are Associated with Epicardial and Visceral Fat Depots in Women with Metabolic Syndrome Criteria International Journal of Molecular Sciences doi: 10.3390/ijms20235981 Authors: Federico Carbone Maria Stefania Lattanzio Silvia Minetti Anna Maria Ansaldo Daniele Ferrara Emilio Molina-Molina Anna Belfiore Edoardo Elia Stefania Pugliese Vincenzo Ostilio Palmieri Fabrizio Montecucco Piero Portincasa Sexual dimorphism...
Wed Nov 27, 2019 02:00
IJMS, Vol. 20, Pages 5978: BIOPEP-UWM Database of Bioactive Peptides: Current Opportunities International Journal of Molecular Sciences doi: 10.3390/ijms20235978 Authors: Minkiewicz Iwaniak Darewicz The BIOPEP-UWM™ database of bioactive peptides (formerly BIOPEP) has recently become a popular tool in the research on bioactive peptides, especially on these derived from foods and being constituents of diets that prevent development of chronic diseases. The database is...
Wed Nov 27, 2019 02:00
IJMS, Vol. 20, Pages 5979: Zinc Binding to Tau Influences Aggregation Kinetics and Oligomer Distribution International Journal of Molecular Sciences doi: 10.3390/ijms20235979 Authors: Moreira Cristóvão Torres Carapeto Rodrigues Landrieu Cordeiro Gomes Metal ions are well known modulators of protein aggregation and are key players in Alzheimer’s Disease, being found to be associated to pathologic protein deposits in diseased brains. Therefore, understanding...
Wed Nov 27, 2019 02:00
IJMS, Vol. 20, Pages 5977: The Role of SINE-VNTR-Alu (SVA) Retrotransposons in Shaping the Human Genome International Journal of Molecular Sciences doi: 10.3390/ijms20235977 Authors: Olympia Gianfrancesco Bethany Geary Abigail L. Savage Kimberley J. Billingsley Vivien J. Bubb John P. Quinn Retrotransposons can alter the regulation of genes both transcriptionally and post-transcriptionally, through mechanisms such as binding transcription factors and alternative splicing...
Wed Nov 27, 2019 02:00
IJMS, Vol. 20, Pages 5976: Connexins-Based Hemichannels/Channels and Their Relationship with Inflammation, Seizures and Epilepsy International Journal of Molecular Sciences doi: 10.3390/ijms20235976 Authors: Laura Medina-Ceja Juan C. Salazar-Sánchez Jorge Ortega-Ibarra Alberto Morales-Villagrán Connexins (Cxs) are a family of 21 protein isoforms, eleven of which are expressed in the central nervous system, and they are found in neurons and glia. Cxs form hemichannels (connexons)...
Wed Nov 27, 2019 02:00
IJMS, Vol. 20, Pages 5974: Genome-Wide Identification and Analysis of the NPR1-Like Gene Family in Bread Wheat and Its Relatives International Journal of Molecular Sciences doi: 10.3390/ijms20235974 Authors: Xian Liu Zhiguo Liu Xinhui Niu Qian Xu Long Yang NONEXPRESSOR OF PATHOGENESIS-RELATED GENES 1 (NPR1), and its paralogues NPR3 and NPR4, are bona fide salicylic acid (SA) receptors and play critical regulatory roles in plant immunity. However, comprehensive identification...
Wed Nov 27, 2019 02:00
IJMS, Vol. 20, Pages 5975: Plasma Levels of snoRNAs are Associated with Platelet Activation in Patients with Peripheral Artery Disease International Journal of Molecular Sciences doi: 10.3390/ijms20235975 Authors: Anne Yaël Nossent Neda Ektefaie Johann Wojta Beate Eichelberger Christoph Kopp Simon Panzer Thomas Gremmel In addition to supervised walking therapy, antithrombotic therapy and the management of risk factors, the treatment of peripheral artery disease (PAD)...
Wed Nov 27, 2019 02:00
IJMS, Vol. 20, Pages 5972: Tight Junctions in Cell Proliferation International Journal of Molecular Sciences doi: 10.3390/ijms20235972 Authors: Mónica Díaz-Coránguez Xuwen Liu David A. Antonetti Tight junction (TJ) proteins form a continuous intercellular network creating a barrier with selective regulation of water, ion, and solutes across endothelial, epithelial, and glial tissues. TJ proteins include the claudin family that confers barrier properties, members of the MARVEL family...
Wed Nov 27, 2019 02:00
IJMS, Vol. 20, Pages 5971: Computer-Assisted Design of Environmentally Friendly and Light-Stable Fluorescent Dyes for Textile Applications International Journal of Molecular Sciences doi: 10.3390/ijms20235971 Authors: Songsong Tang Guoqiang Chen Gang Sun Five potentially environmentally friendly and light-stable hemicyanine dyes were designed based on integrated consideration of photo, environmental, and computational chemistry as well as textile applications. Two of them were...
Wed Nov 27, 2019 02:00
IJMS, Vol. 20, Pages 5970: Transcriptomic Insights into Innate Immunity Responding to Red Rot Disease in Red Alga Pyropia yezoensis International Journal of Molecular Sciences doi: 10.3390/ijms20235970 Authors: Lei Tang Liping Qiu Cong Liu Guoying Du Zhaolan Mo Xianghai Tang Yunxiang Mao Pyropia yezoensis, one of the most economically important marine algae, suffers from the biotic stress of the oomycete necrotrophic pathogen Pythium porphyrae. However, little is known...
Wed Nov 27, 2019 02:00
IJMS, Vol. 20, Pages 5973: Experimental Measurement and Modeling of Hg(II) Removal from Aqueous Solutions Using Eucalyptus globulus Bark: Effect of pH, Salinity and Biosorbent Dosage International Journal of Molecular Sciences doi: 10.3390/ijms20235973 Authors: Elaine Fabre Carlos Vale Eduarda Pereira Carlos M. Silva Different experimental conditions were tested in order to optimize the Hg(II) removal by Eucalyptus globulus bark. Response surface methodology was applied to extract...
Wed Nov 27, 2019 02:00
JCM, Vol. 8, Pages 2076: Basic Human Body Dimensions Relate to Alcohol Dependence and Predict Hospital Readmission Journal of Clinical Medicine doi: 10.3390/jcm8122076 Authors: Lenz Köllner Mühle Weinland Kornhuber Alcohol dependence is a severe mental illness and there is a need for more effective preventive and therapeutic strategies. Translational research suggests that intrauterine sex hormone exposure modulates the risk and course of alcohol dependence during adulthood....
Wed Nov 27, 2019 02:00
JCM, Vol. 8, Pages 2075: Biomarkers of Vascular Injury and Type 2 Diabetes: A Prospective Study, Systematic Review and Meta-Analysis Journal of Clinical Medicine doi: 10.3390/jcm8122075 Authors: Laura Pletsch-Borba Cora Watzinger Renée Turzanski Fortner Verena Katzke Lukas Schwingshackl Solomon A. Sowah Anika Hüsing Theron Johnson Marie-Luise Groß Sandra González Maldonado Michael Hoffmeister Peter Bugert Rudolf Kaaks Mirja Grafetstätter Tilman Kühn...
Wed Nov 27, 2019 02:00
JCM, Vol. 8, Pages 2074: Association of Maternal Weight and Gestational Weight Gain with Maternal and Neonate Outcomes: A Prospective Cohort Study Journal of Clinical Medicine doi: 10.3390/jcm8122074 Authors: Damien Bouvier Jean-Claude Forest Emilie Dion-Buteau Nathalie Bernard Emmanuel Bujold Bruno Pereira Yves Giguère We investigated the association of outcomes with pre-pregnancy body mass index (ppBMI), Institute of Medicine (IOM) recommendations about gestational...
Wed Nov 27, 2019 02:00
JFB, Vol. 10, Pages 54: Phosphoserine Functionalized Cements Preserve Metastable Phases, and Reprecipitate Octacalcium Phosphate, Hydroxyapatite, Dicalcium Phosphate, and Amorphous Calcium Phosphate, during Degradation, In Vitro Journal of Functional Biomaterials doi: 10.3390/jfb10040054 Authors: Joseph Lazraq Bystrom Michael Pujari-Palmer Phosphoserine modified cements (PMC) exhibit unique properties, including strong adhesion to tissues and biomaterials. While TTCP-PMCs remodel...
Wed Nov 27, 2019 02:00
Medical Sciences, Vol. 7, Pages 107: Naturally Occurring and Experimentally Induced Rhesus Macaque Models for Polycystic Ovary Syndrome: Translational Gateways to Clinical Application Medical Sciences doi: 10.3390/medsci7120107 Authors: Abbott Rogers Dumesic Levine Indian rhesus macaque nonhuman primate models for polycystic ovary syndrome (PCOS) implicate both female hyperandrogenism and developmental molecular origins as core components of PCOS etiopathogenesis. Establishing...
Wed Nov 27, 2019 02:00
Medical Sciences, Vol. 7, Pages 106: Narcolepsy in Children and Adults: A Guide to Improved Recognition, Diagnosis and Management Medical Sciences doi: 10.3390/medsci7120106 Authors: Morse Narcolepsy is a rare condition that affects children and adults, and commonly has an onset in childhood. Time to appropriate diagnosis frequently is at least a decade. Unrecognized or misdiagnosed symptoms of narcolepsy contribute to increased morbidity, disability and socioeconomic liability in these...
Wed Nov 27, 2019 02:00
Medicina, Vol. 55, Pages 760: Comparison of Laryngoscopic Views betweenC-MAC™ and Conventional Laryngoscopy in Patients with Multiple Preoperative Prognostic Criteria of Difficult Intubation. An Observational Cross-Sectional Study Medicina doi: 10.3390/medicina55120760 Authors: Amaniti Papakonstantinou Gkinas Dalakakis Papapostolou Nikopoulou Tsatali Zarogoulidis Sapalidis Kosmidis Koulouris Giannakidis Romanidis Oikonomou Michalopoulos...
Wed Nov 27, 2019 02:00
Membranes, Vol. 9, Pages 159: Membrane Adsorber for the Fast Purification of a Monoclonal Antibody Using Protein A Chromatography Membranes doi: 10.3390/membranes9120159 Authors: Chantal Brämer Lisa Tünnermann Alina Gonzalez Salcedo Oscar-Werner Reif Dörte Solle Thomas Scheper Sascha Beutel Monoclonal antibodies are conquering the biopharmaceutical market because they can be used to treat a variety of diseases. Therefore, it is very important to establish robust and...
Wed Nov 27, 2019 02:00
Metabolites, Vol. 9, Pages 292: Ammonium Fluoride as Suitable Additive for HILIC-Based LC-HRMS Metabolomics Metabolites doi: 10.3390/metabo9120292 Authors: Luca Narduzzi Anne-Lise Royer Emmanuelle Bichon Yann Guitton Corinne Buisson Bruno Le Bizec Gaud Dervilly-Pinel Hydrophilic Interaction Liquid Chromatography (HILIC) chromatography is widely applied in metabolomics as a complementary strategy to reverse phase chromatography. Nevertheless, it still faces several issues...
Wed Nov 27, 2019 02:00
Metabolites, Vol. 9, Pages 291: Mucosal Metabolomic Profiling and Pathway Analysis Reveal the Metabolic Signature of Ulcerative Colitis Metabolites doi: 10.3390/metabo9120291 Authors: Joseph Diab Terkel Hansen Rasmus Goll Hans Stenlund Einar Jensen Thomas Moritz Jon Florholmen Guro Forsdahl The onset of ulcerative colitis (UC) is characterized by a dysregulated mucosal immune response triggered by several genetic and environmental factors in the context of host–microbe...
Wed Nov 27, 2019 02:00
Microorganisms, Vol. 7, Pages 621: Phytoplankton and Bacterial Community Structure in Two Chinese Lakes of Different Trophic StatusMicroorganisms doi: 10.3390/microorganisms7120621Authors: Feng Jia Wang Han Dong Huo Li LiuPhytoplankton are the primary producers at the basis of aquatic food webs, and bacteria play an important role in energy flow and biochemical cycling in aquatic ecosystems. In this study, both the bacterial and phytoplankton communities were examined in the oligotrophic Lake Basomtso...
Wed Nov 27, 2019 02:00
Microorganisms, Vol. 7, Pages 620: Time Integrated Flux Analysis: Exploiting the Concentration Measurements Directly for Cost-Effective Metabolic Network Flux AnalysisMicroorganisms doi: 10.3390/microorganisms7120620Authors: Portela Richelle Dumas von StoschBackground: Flux analyses, such as Metabolic Flux Analysis (MFA), Flux Balance Analysis (FBA), Flux Variability Analysis (FVA) or similar methods, can provide insights into the cellular metabolism, especially in combination with experimental data....
Wed Nov 27, 2019 02:00
Molecules, Vol. 24, Pages 4344: Dual Insecticidal Effects of Adenanthera pavonina Kunitz-Type Inhibitor on Plodia interpunctella is Mediated by Digestive Enzymes Inhibition and Chitin-Binding Properties Molecules doi: 10.3390/molecules24234344 Authors: Caio Fernando Ramalho de Oliveira Taylla Michelle de Oliveira Flores Marlon Henrique Cardoso Karen Garcia Nogueira Oshiro Raphael Russi Anderson Felipe Jácome de França Elizeu Antunes dos Santos Octávio Luiz Franco Adeliana...
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Molecules, Vol. 24, Pages 4343: Synthesis of Bis-Glyoxylamide Peptidomimetics Derived from Bis-N-acetylisatins Linked at C5 by a Methylene or Oxygen Bridge Molecules doi: 10.3390/molecules24234343 Authors: Suryanti Zhang Aldilla Bhadbhade Kumar Black The bis-glyoxylamide peptidomimetics have been synthesized from bis-N-acetylisatins linked at C5 by ring-opening with alcohols, amines, and amino acid methyl ester hydrochlorides. X-ray images of single crystals of bis-glyoxylamide...
Wed Nov 27, 2019 02:00
Molecules, Vol. 24, Pages 4342: Plant-Mediated Enantioselective Transformation of Indan-1-one and Indan-1-ol. Part 2 Molecules doi: 10.3390/molecules24234342 Authors: Mączka Wińska Grabarczyk Galek The main purpose of this publication was to obtain the S-enantiomer of indan-1-ol with high enantiomeric excess and satisfactory yield. In our research, we used carrot callus cultures (Daucus carota L.), whereby the enzymatic system reduced indan-1-one and oxidized indan-1-ol....
Wed Nov 27, 2019 02:00
Molecules, Vol. 24, Pages 4341: Grape Berry Flavonoid Responses to High Bunch Temperatures Post Véraison: Effect of Intensity and Duration of Exposure Molecules doi: 10.3390/molecules24234341 Authors: Julia C. Gouot Jason P. Smith Bruno P. Holzapfel Celia Barril Climate models predict an increase in the frequency and duration of heatwaves with an increase in intensity already strongly evident worldwide. The aim of this work was to evaluate the effect of two heatwave-related...
Wed Nov 27, 2019 02:00
Molecules, Vol. 24, Pages 4340: Synthesis and Comparative Structure–Activity Study of Carbohydrate-Based Phenolic Compounds as α-Glucosidase Inhibitors and Antioxidants Molecules doi: 10.3390/molecules24234340 Authors: Shota Machida Saki Mukai Rina Kono Megumi Funato Hiroaki Saito Taketo Uchiyama Twenty-one natural and unnatural phenolic compounds containing a carbohydrate moiety were synthesized and their structure–activity relationship (SAR) was evaluated for...
Wed Nov 27, 2019 02:00
Molecules, Vol. 24, Pages 4339: Green Chemistry Extractions of Carotenoids from Daucus carota L.—Supercritical Carbon Dioxide and Enzyme-Assisted Methods Molecules doi: 10.3390/molecules24234339 Authors: Natalia Miękus Aamir Iqbal Krystian Marszałek Czesław Puchalski Artur Świergiel Multiple reviews have been published on various aspects of carotenoid extraction. Nevertheless, none of them focused on the discussion of recent green chemistry extraction protocols, especially...
Wed Nov 27, 2019 02:00
Molecules, Vol. 24, Pages 4338: PpNAC187 Enhances Lignin Synthesis in ‘Whangkeumbae’ Pear (Pyrus pyrifolia) ‘Hard-End’ Fruit Molecules doi: 10.3390/molecules24234338 Authors: Mingtong Li Chenxia Cheng Xinfu Zhang Suping Zhou Caihong Wang Chunhui Ma Shaolan Yang A disorder in pears that is known as ‘hard-end’ fruit affects the appearance, edible quality, and market value of pear fruit. RNA-Seq was carried out on the calyx end of ‘Whangkeumbae’...
Wed Nov 27, 2019 02:00
Molecules, Vol. 24, Pages 4337: Correlation Between the Water Solubility and Secondary Structure of Tilapia-Soybean Protein Co-Precipitates Molecules doi: 10.3390/molecules24234337 Authors: Li Tan Pengzhi Hong Ping Yang Chunxia Zhou Dinghao Xiao Tanjun Zhong The secondary structure of a protein has been identified to be a crucial indicator that governs its water solubility. Tilapia protein isolate (TPI), soybean protein isolate (SPI), and tilapia-soybean protein co-precipitates...
Wed Nov 27, 2019 02:00
Molecules, Vol. 24, Pages 4332: New Insight on the Study of the Kinetic of Biobased Polyurethanes Synthesis Based on Oleo-Chemistry Molecules doi: 10.3390/molecules24234332 Authors: Julien Peyrton Clémence Chambaretaud Luc Avérous Nowadays, polyols are basic chemicals for the synthesis of a large range of polymers, such as polyurethane foams (PUF), which are produced with several other compounds, such as polyisocyanates. During the last decades, the oleo-chemistry has developed...
Wed Nov 27, 2019 02:00
Molecules, Vol. 24, Pages 4335: A Switch between Antioxidant and Prooxidant Properties of the Phenolic Compounds Myricetin, Morin, 3′,4′-Dihydroxyflavone, Taxifolin and 4-Hydroxy-Coumarin in the Presence of Copper(II) Ions: A Spectroscopic, Absorption Titration and DNA Damage Study Molecules doi: 10.3390/molecules24234335 Authors: Klaudia Jomová Lenka Hudecova Peter Lauro Miriama Simunkova Saleh H. Alwasel Ibrahim M. Alhazza Marian Valko The beneficial effects of polyphenols,...
Wed Nov 27, 2019 02:00
Molecules, Vol. 24, Pages 4336: Effects of Different Colored LEDs on the Enhancement of Biologically Active Ingredients in Callus Cultures of Gynura procumbens (Lour.) Merr. Molecules doi: 10.3390/molecules24234336 Authors: Thang Tung Lian Se-Yeoun Cha Myat Myat Moe Yong Ju Kim Keuk Soo Bang Conventional fluorescent lamps that are used in tissue culture are costly light sources, exhibiting excessive wavelength emission-bandwidth that must be replaced by alternative, less...
Wed Nov 27, 2019 02:00
Nanomaterials, Vol. 9, Pages 1696: Bismuth-Doped Nanohydroxyapatite Coatings on Titanium Implants for Improved Radiopacity and Antimicrobial Activity Nanomaterials doi: 10.3390/nano9121696 Authors: Ciobanu Harja This study aims to present the possibility to obtain bismuth-doped nanohydroxyapatite coatings on the surface of the titanium implants by using a solution-derived process according to an established biomimetic methodology. The bioactivity of the titanium surface was increased...
Wed Nov 27, 2019 02:00
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