IJMS, Vol. 20, Pages 5900: Diagnostic Cytokines and Comparative Analysis Secreted from Exfoliated Deciduous Teeth, Dental Pulp, and Bone Marrow Derived Mesenchymal Stem Cells for Functional Cell-Based Therapy International Journal of Molecular Sciences doi: 10.3390/ijms20235900 Authors: Yoichi Yamada Sayaka Nakamura-Yamada Eri Umemura-Kubota Shunsuke Baba The aim of the study was to clarify the distinctive features of stem cells for effective cell-based therapy strategies in...
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IJMS, Vol. 20, Pages 5899: Remote Ischemic Preconditioning and Diazoxide Protect from Hepatic Ischemic Reperfusion Injury by Inhibiting HMGB1-Induced TLR4/MyD88/NF-κB Signaling International Journal of Molecular Sciences doi: 10.3390/ijms20235899 Authors: Won Uk Koh Jiye Kim Jooyoung Lee Gi-Won Song Gyu Sam Hwang Eunyoung Tak Jun-Gol Song Remote ischemic preconditioning (RIPC) is known to have a protective effect against hepatic ischemia-reperfusion (IR) injury in animal...
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IJMS, Vol. 20, Pages 5896: Caspase-8 Regulates Endoplasmic Reticulum Stress-Induced Necroptosis Independent of the Apoptosis Pathway in Auditory Cells International Journal of Molecular Sciences doi: 10.3390/ijms20235896 Authors: Kishino Hayashi Maeda Jike Hidai Nomura Oshima The aim of this study is to elucidate the detailed mechanism of endoplasmic reticulum (ER) stress-induced auditory cell death based on the function of the initiator caspases and molecular...
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IJMS, Vol. 20, Pages 5897: Advances in Sphingolipidoses: CRISPR-Cas9 Editing as an Option for Modelling and Therapy International Journal of Molecular Sciences doi: 10.3390/ijms20235897 Authors: Renato Santos Olga Amaral Sphingolipidoses are inherited genetic diseases characterized by the accumulation of glycosphingolipids. Sphingolipidoses (SP), which usually involve the loss of sphingolipid hydrolase function, are of lysosomal origin, and represent an important group of rare diseases...
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IJMS, Vol. 20, Pages 5898: Glucose Transport and Transporters in the Endomembranes International Journal of Molecular Sciences doi: 10.3390/ijms20235898 Authors: Beáta Lizák András Szarka Yejin Kim Kyu-sung Choi Csilla E. Németh Paola Marcolongo Angelo Benedetti Gábor Bánhegyi Éva Margittai Glucose is a basic nutrient in most of the creatures; its transport through biological membranes is an absolute requirement of life. This role is fulfilled by glucose transporters,...
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IJMS, Vol. 20, Pages 5901: Sphingolipids in Obesity and Correlated Co-Morbidities: The Contribution of Gender, Age and Environment International Journal of Molecular Sciences doi: 10.3390/ijms20235901 Authors: Torretta Barbacini Al-Daghri Gelfi This paper reviews our present knowledge on the contribution of ceramide (Cer), sphingomyelin (SM), dihydroceramide (DhCer) and sphingosine-1-phosphate (S1P) in obesity and related co-morbidities. Specifically, in this paper, we address...
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IJMS, Vol. 20, Pages 5891: Combined Effect of Cadmium and Lead on Durum Wheat International Journal of Molecular Sciences doi: 10.3390/ijms20235891 Authors: Alessio Aprile Erika Sabella Enrico Francia Justyna Milc Domenico Ronga Nicola Pecchioni Erika Ferrari Andrea Luvisi Marzia Vergine Luigi De Bellis Cadmium (Cd) and lead (Pb) are two toxic heavy metals (HMs) whose presence in soil is generally low. However, industrial and agricultural activities in recent...
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IJMS, Vol. 20, Pages 5894: Promising Therapeutic Efficacy of GC1118, an Anti-EGFR Antibody, against KRAS Mutation-Driven Colorectal Cancer Patient-Derived Xenografts International Journal of Molecular Sciences doi: 10.3390/ijms20235894 Authors: Hye Won Lee Eunju Son Kyoungmin Lee Yeri Lee Yejin Kim Jae-Chul Lee Yangmi Lim Minkyu Hur Donggeon Kim Do-Hyun Nam Epidermal growth factor receptor (EGFR)-targeted monoclonal antibodies, including cetuximab and panitumumab,...
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IJMS, Vol. 20, Pages 5892: Analysis of Pollen Allergens in Lily by Transcriptome and Proteome Data International Journal of Molecular Sciences doi: 10.3390/ijms20235892 Authors: Feng Wu Wang Zhang Teng The lily (Lilium spp.) anther contains a lot of pollen. It is not known if lily pollen contains allergens, and therefore screening pollen allergy-related proteins and genes is necessary. The pollen development period of lily ‘Siberia’ was determined...
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IJMS, Vol. 20, Pages 5893: An Integrated Analysis of the Rice Transcriptome and Metabolome Reveals Root Growth Regulation Mechanisms in Response to Nitrogen Availability International Journal of Molecular Sciences doi: 10.3390/ijms20235893 Authors: Wei Xin Lina Zhang Wenzhong Zhang Jiping Gao Jun Yi Xiaoxi Zhen Ming Du Yanze Zhao Liqiang Chen Nitrogen is an essential nutrient for plant growth and basic metabolic processes. Root systems play an important role in...
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IJMS, Vol. 20, Pages 5895: The Omega-3 Fatty Acids EPA and DHA, as a Part of a Murine High-Fat Diet, Reduced Lipid Accumulation in Brown and White Adipose Tissues International Journal of Molecular Sciences doi: 10.3390/ijms20235895 Authors: Nikul Soni Alastair B. Ross Nathalie Scheers Intawat Nookaew Britt G. Gabrielsson Ann-Sofie Sandberg Excess energy intake can trigger an uncontrolled inflammatory response, leading to systemic low-grade inflammation and metabolic disturbances...
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IJMS, Vol. 20, Pages 5890: Stability and Fermentability of Green Tea Flavonols in In-Vitro-Simulated Gastrointestinal Digestion and Human Fecal Fermentation International Journal of Molecular Sciences doi: 10.3390/ijms20235890 Authors: Chan-Su Rha Hyunbin Seong Young Sung Jung Davin Jang Jun-Gu Kwak Dae-Ok Kim Nam Soo Han Flavonols, the second most abundant flavonoids in green tea, exist mainly in the form of glycosides. Flavonols are known to have a variety of beneficial...
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IJMS, Vol. 20, Pages 5889: Chitosan as a Wound Dressing Starting Material: Antimicrobial Properties and Mode of Action International Journal of Molecular Sciences doi: 10.3390/ijms20235889 Authors: Matica Aachmann Tøndervik Sletta Ostafe Fighting bacterial resistance is one of the concerns in modern days, as antibiotics remain the main resource of bacterial control. Data shows that for every antibiotic developed, there is a microorganism that becomes resistant to it....
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IJMS, Vol. 20, Pages 5888: Static Solid Relaxation Ordered Spectroscopy: SS-ROSY International Journal of Molecular Sciences doi: 10.3390/ijms20235888 Authors: Gregory S. Boutis Ravinath Kausik A two-dimensional pulse sequence is introduced for correlating nuclear magnetic resonance anisotropic chemical shifts to a relaxation time (e.g., T1) in solids under static conditions. The sequence begins with a preparatory stage for measuring relaxation times, and is followed by a multiple...
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IJMS, Vol. 20, Pages 5887: Identification of a Major QTL (qRRs-10.1) That Confers Resistance to Ralstonia solanacearum in Pepper (Capsicum annuum) Using SLAF-BSA and QTL Mapping International Journal of Molecular Sciences doi: 10.3390/ijms20235887 Authors: Heshan Du Changlong Wen Xiaofen Zhang Xiulan Xu Jingjing Yang Bin Chen Sansheng Geng The soilborne pathogen Ralstonia solanacearum is the causal agent of bacterial wilt (BW), a major disease of pepper (Capsicum annuum)....
Sat Nov 23, 2019 02:00
IJMS, Vol. 20, Pages 5886: ABCC3 Expressed by CD56dim CD16+ NK Cells Predicts Response in Glioblastoma Patients Treated with Combined Chemotherapy and Dendritic Cell Immunotherapy International Journal of Molecular Sciences doi: 10.3390/ijms20235886 Authors: Pellegatta Ianni Pessina Paterra Anghileri Eoli Finocchiaro Recently, we found that temozolomide (TMZ) can upregulate the expression of the multidrug-resistance protein ABCC3 in NK cells from both glioma-bearing...
Sat Nov 23, 2019 02:00
IJMS, Vol. 20, Pages 5885: Current Treatment Strategies and Nanoparticle-Mediated Drug Delivery Systems for Pulmonary Arterial Hypertension International Journal of Molecular Sciences doi: 10.3390/ijms20235885 Authors: Kazufumi Nakamura Satoshi Akagi Kentaro Ejiri Masashi Yoshida Toru Miyoshi Norihisa Toh Koji Nakagawa Yoichi Takaya Hiromi Matsubara Hiroshi Ito There are three critical pathways for the pathogenesis and progression of pulmonary arterial hypertension...
Sat Nov 23, 2019 02:00
IJMS, Vol. 20, Pages 5884: The Biological Bases of Group 2 Pulmonary Hypertension International Journal of Molecular Sciences doi: 10.3390/ijms20235884 Authors: Ana I. Fernández Raquel Yotti Ana González-Mansilla Teresa Mombiela Enrique Gutiérrez-Ibanes Candelas Pérez del Villar Paula Navas-Tejedor Christian Chazo Pablo Martínez-Legazpi Francisco Fernández-Avilés Javier Bermejo Pulmonary hypertension (PH) is a potentially fatal condition with a prevalence...
Sat Nov 23, 2019 02:00
IJMS, Vol. 20, Pages 5882: phyB and HY5 are Involved in the Blue Light-Mediated Alleviation of Dormancy of Arabidopsis Seeds Possibly via the Modulation of Expression of Genes Related to Light, GA, and ABA International Journal of Molecular Sciences doi: 10.3390/ijms20235882 Authors: Marlena Stawska Krystyna Oracz Light is one of the most important environmental factors regulating seed germination. It is known that light inhibits seed germination of some monocotyledonous species and...
Sat Nov 23, 2019 02:00
IJMS, Vol. 20, Pages 5883: Genome-Wide Transcriptome Analysis of Rice Seedlings after Seed Dressing with Paenibacillus yonginensis DCY84T and Silicon International Journal of Molecular Sciences doi: 10.3390/ijms20235883 Authors: Yo-Han Yoo Minjae Kim Anil Kumar Nalini Chandran Woo-Jong Hong Hye Ryun Ahn Gang Taik Lee Sungju Kang Dabin Suh Jin-O Kim Yeon-Ju Kim Ki-Hong Jung Plant-growth-promoting bacteria (PGPB) are beneficial microorganisms that can also...
Sat Nov 23, 2019 02:00
JCM, Vol. 8, Pages 2066: Family and School Contexts as Predictors of Suicidal Behavior among Adolescents: The Role of Depression and Anxiety Journal of Clinical Medicine doi: 10.3390/jcm8122066 Authors: Nicolás Ruiz-Robledillo Rosario Ferrer-Cascales Natalia Albaladejo-Blázquez Miriam Sánchez-SanSegundo Suicide is the highest external cause of death in the majority of developed countries. In adolescents, the prevalence of suicide has increased significantly in recent years,...
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JCM, Vol. 8, Pages 2067: Early retinal flow changes after vitreoretinal surgery in idiopathic epiretinal membrane using swept source optical coherence tomography angiography Journal of Clinical Medicine doi: 10.3390/jcm8122067 Authors: Mastropasqua D’Aloisio Viggiano Borrelli Iafigliola Di Nicola Aharrh-Gnama Di Marzio Toto Mariotti Carpineto (1) Background: The aim of this observational cross-sectional work was to investigate early retinal vascular...
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JCM, Vol. 8, Pages 2065: The Influence of Histologic Inflammation on the Improvement of Liver Stiffness Values Over 1 and 3 Years Journal of Clinical Medicine doi: 10.3390/jcm8122065 Authors: Jeong-Ju Yoo Yeon Seok Seo Young Seok Kim Soung Won Jeong Jae Young Jang Sang Jun Suh Hyung Joon Yim Ki Tae Suk Dong Joon Kim Kwang-Hyub Han Seung Up Kim Bora Lee Sang Gyune Kim Background: Transient elastography is now an indispensable tool for estimating liver...
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JCM, Vol. 8, Pages 2064: Plasma Vitamin C and Cancer Mortality in Kidney Transplant Recipients Journal of Clinical Medicine doi: 10.3390/jcm8122064 Authors: Gacitúa Sotomayor Groothof Eisenga Pol Borst Gans Berger Rodrigo Navis Bakker There is a changing trend in mortality causes in kidney transplant recipients (KTR), with a decline in deaths due to cardiovascular causes along with a relative increase in cancer mortality rates. Vitamin C, a well-known...
Sat Nov 23, 2019 02:00
JCM, Vol. 8, Pages 2063: Safety and Effectiveness of Shoulder Arthroplasties in Spain: A Systematic Review Journal of Clinical Medicine doi: 10.3390/jcm8122063 Authors: Torre Garcia Smith Romero-Tamarit Puigdomenech Muñoz-Ortiz Evans Martín Molina Torrens Pons-Cabrafiga Pallisó Valderas Espallargues The effectiveness and safety of shoulder arthroplasties in the general context of a Spanish patient population remains unclear. The aim...
Sat Nov 23, 2019 02:00
JDB, Vol. 7, Pages 21: Nematode Autotomy Requires Molting and Entails Tissue Healing without Obvious Regeneration Journal of Developmental Biology doi: 10.3390/jdb7040021 Authors: Jonathan Hodgkin Autotomy in C. elegans, which results in the severing of the body into two fragments, has been observed as a response to late larval worm-star formation after exposure to a bacterial surface pathogen. It was found that autotomy can occur in both hermaphroditic and gonochoristic nematode species,...
Sat Nov 23, 2019 02:00
J. Imaging, Vol. 5, Pages 88: Software-Based Three-Dimensional Deconvolution Microscopy of Cytoskeletal Proteins in Cultured Fibroblast Using Open-Source Software and Open Hardware Journal of Imaging doi: 10.3390/jimaging5120088 Authors: Katoh As conventional fluorescence microscopy and confocal laser scanning microscopy generally produce images with blurring at the upper and lower planes along the z-axis due to non-focal plane image information, the observation of biological images...
Sat Nov 23, 2019 02:00
Membranes, Vol. 9, Pages 156: ZnO Microfiltration Membranes for Desalination by a Vacuum Flow-Through Evaporation Method Membranes doi: 10.3390/membranes9120156 Authors: Dangwal Liu Bastatas Echeverria Huang Mao Mcllroy Han Kim ZnO was deposited on macroporous α-alumina membranes via atomic layer deposition (ALD) to improve water flux by increasing their hydrophilicity and reducing mass transfer resistance through membrane pore channels. The...
Sat Nov 23, 2019 02:00
MPs, Vol. 2, Pages 89: Optimized Extraction of Insect Genomic DNA for Long-Read Sequencing Methods and Protocols doi: 10.3390/mps2040089 Authors: Oppert Stoss Monk Smith Long-read sequencing technologies continue to increase the length of reads, and at present can average read lengths of >20 kb up to 60–80 kb. Now the challenge is to extract genomic DNA of sufficient fragment size and quality to support longer read lengths. We developed a successful method...
Sat Nov 23, 2019 02:00
Microorganisms, Vol. 7, Pages 611: Elevation is Associated with Human Skin MicrobiomesMicroorganisms doi: 10.3390/microorganisms7120611Authors: Li Wang Yu Feng Zhou Shao Qu Li Bo Zhou Human skin microbiota plays a crucial role in the defense against pathogens, and is associated with various skin diseases. High elevation is positively correlated with various extreme environmental conditions (i.e., high ultraviolet radiation), which may exert selection pressure on skin microbiota, and therefore influence...
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Molbank, Vol. 2019, Article M1095: Pyridine-Imidazlolium Salts: Oxidatively Cleavage of N-C Bond via Nitration Molbank doi: 10.3390/M1095 Authors: Cucu (Diaconu) Mangalagiu Azaheterocycles derivatives with pyridine-imidazole skeleton are compounds of great value for medicinal chemistry. We report herein the nitration of 1,1’-(pyridine-2,6-diylbis(methylene))bis{3-[2-(4-nitrophenyl)-2-oxoethyl]-1H-imidazol-3-ium} bromide using a typical mixture of nitric and sulphuric acid....
Sat Nov 23, 2019 02:00
Molecules, Vol. 24, Pages 4281: Carbon Nanotubes Having Haeckelite Defects as Potential Drug Carriers. Molecular Dynamics Simulation Molecules doi: 10.3390/molecules24234281 Authors: Camila Torres Ignacio Villarroel Roberto Rozas Leonor Contreras Carbon nanotubes (CNTs) are valuable drug carriers since when properly functionalized they transport drugs and anchor directly to cancerous tumors whose more acidic pH causes the drug release. Herein, we study the so-called zigzag and...
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Molecules, Vol. 24, Pages 4279: Reductive Metabolism of Ellagitannins in the Young Leaves of Castanopsis sieboldii Molecules doi: 10.3390/molecules24234279 Authors: Hatsumi Wakamatsu Sumire Tanaka Yosuke Matsuo Yoshinori Saito Koyo Nishida Takashi Tanaka The leaves of Castanopsis sieboldii (Fagaceae) contain characteristic hexahydroxydiphenoyl (HHDP) esters of 28-O-glucosyl 2α,3β,23,24-tetrahydroxyolean- and urs-12-en-28-oic acids. In this study, uncharacterized...
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Molecules, Vol. 24, Pages 4278: Antiangiogenic Effects of Coumarins against Cancer: From Chemistry to Medicine Molecules doi: 10.3390/molecules24234278 Authors: Mohammad Bagher Majnooni Sajad Fakhri Antonella Smeriglio Domenico Trombetta Courtney R. Croley Piyali Bhattacharyya Eduardo Sobarzo-Sánchez Mohammad Hosein Farzaei Anupam Bishayee Angiogenesis, the process of formation and recruitment of new blood vessels from pre-existing vessels, plays an important...
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Molecules, Vol. 24, Pages 4280: Antimicrobial Activity and Chemical Constitution of the Crude, Phenolic-Rich Extracts of Hibiscus sabdariffa, Brassica oleracea and Beta vulgaris Molecules doi: 10.3390/molecules24234280 Authors: Seham Abdel-Shafi Abdul-Raouf Al-Mohammadi Mahmoud Sitohy Basma Mosa Ahmed Ismaiel Gamal Enan Ali Osman Crude, phenolic-rich extracts (CPREs) were isolated from different sources, such as Hibiscus sabdariffa (H. sabdariffa), Brassica oleracea...
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Molecules, Vol. 24, Pages 4277: Applications of Tea (Camellia sinensis) and its Active Constituents in Cosmetics Molecules doi: 10.3390/molecules24234277 Authors: Koch Zagórska Marzec Kukula-Koch Studies on the cosmetic applications of plant extracts are increasingly appearing in the scientific literature, which is due to the growing popularity of skincare products around the world. In the light of the observed changes, a return to natural treatment and skincare with cosmetics...
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Molecules, Vol. 24, Pages 4276: Prenyleudesmanes and A Hexanorlanostane from the Roots of Lonicera macranthoides Molecules doi: 10.3390/molecules24234276 Authors: Hui Lyu Wenjuan Liu Bai Bai Yu Shan Christian Paetz Xu Feng Yu Chen Three previously undescribed compounds, two prenyleudesmanes (1 and 2), and one hexanorlanostane (3), were isolated from the roots of Lonicera macranthoides. Their structures were established based on 1D and 2D nuclear magnetic resonance (NMR)...
Sat Nov 23, 2019 02:00
Molecules, Vol. 24, Pages 4274: The Halogen-Bond Nature in Noble Gas–Dihalogen Complexes from Scattering Experiments and Ab Initio Calculations Molecules doi: 10.3390/molecules24234274 Authors: Francesca Nunzi Benedetta Di Erasmo Francesco Tarantelli David Cappelletti Fernando Pirani In order to clarify the nature of the halogen bond (XB), we considered the prototype noble gas–dihalogen molecule (Ng–X2) systems, focusing on the nature, range, and strength...
Sat Nov 23, 2019 02:00
Molecules, Vol. 24, Pages 4272: Lipase-Catalyzed Chemoselective Ester Hydrolysis of Biomimetically Coupled Aryls for the Synthesis of Unsymmetric Biphenyl Esters Molecules doi: 10.3390/molecules24234272 Authors: Janna Ehlert Jenny Kronemann Nadine Zumbrägel Matthias Preller Lipases are among the most frequently used biocatalysts in organic synthesis, allowing numerous environmentally friendly and inexpensive chemical transformations. Here, we present a biomimetic strategy based...
Sat Nov 23, 2019 02:00
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