Authors: Emilie Dama, Oumou Camara, Dramane Kaba, Mathurin Koffi, Mamadou Camara, Charlie Compaoré, Hamidou Ilboudo, Fabrice Courtin, Jacques Kaboré, Emmanuel Kouassi N’Gouan, Philippe Büscher, Veerle Lejon, Bruno Bucheton and Vincent Jamonneau.Parasite Vol. 26 , page 68Published online: 22/11/2019 Keywords: Human African Trypanosomiasis ; Trypanosoma brucei gambiense ; Elimination ; Diagnosis ; Transmission ; Immune trypanolysis.
Fri Nov 22, 2019 02:00
Authors: Amira Chaabane, Olivier Verneau and Louis Du Preez.Parasite Vol. 26 , page 67Published online: 20/11/2019 Keywords: Indopolystoma ; Polystoma ; Asia ; Neobatrachia ; Rhacophoridae.
Wed Nov 20, 2019 02:00
Authors: František Moravec and Jean-Lou Justine.Parasite Vol. 26 , page 66Published online: 20/11/2019 Keywords: Nematoda ; Helminth parasite ; Camallanoidea ; Aulopiformes ; Carcharhiniformes ; Perciformes ; Pleuronectiformes ; Serpentes ; South Pacific.
Wed Nov 20, 2019 02:00
Authors: Cintli Martínez-Ortiz-de-Montellano, Juan Felipe de Jesús Torres-Acosta, Isabelle Fourquaux, Carlos Alfredo Sandoval-Castro and Hervé Hoste.Parasite Vol. 26 , page 65Published online: 18/11/2019 Keywords: Ultrastructural changes ; Haemonchus contortus ; Polyphenol-rich plants ; Goats.
Mon Nov 18, 2019 02:00
Abstract Background Numerous studies have demonstrated that the pigmentation of iris and around the eyelid is a common side effect of latanoprost, a prostaglandin F2alpha analogue used in the treatment of glaucoma. Hence, we decided to study the effectiveness of topical latanoprost on vitiligo patches around the eyelid. Methods In this randomized, double blind, clinical trial study, 31 patients with vitiligo vulgaris and focal vitiligo involving the eyelids were evaluated. Patients were...
Sat Nov 23, 2019 17:53
Abstract Objective Systemic inflammatory responses in cancer patients are important factors for nutrition and prognosis. This study evaluates the association between tooth loss, occlusal status, prognostic nutritional index (PNI). Methods 93 patients with gastric cancer were included. These parameters were investigated: stage, body mass index (BMI), total lymphocyte count, C‐reactive protein (CRP), PNI, albumin (ALB). Patients were divided into three groups by Eichner classification (Group...
Sat Nov 23, 2019 20:18
Abstract Objectives To investigate the molecular pathogenesis of implant‐associated peripheral giant cell granuloma (IA‐PGCG). Methods A convenience sample of 15 IA‐PGCG cases was selected. Hotspot mutations of KRAS, FGFR1, and TRPV4 genes, previously reported in conventional giant cell lesions of the jaws, were investigated by Sanger sequencing. As these mutations could activate MAPK/ERK pathway, the expression of phospho‐ERK1/2 was also evaluated by immunohistochemistry. Results...
Sat Nov 23, 2019 15:24
Abstract Objectives We performed a randomized clinical study evaluating the stability of implants with different surfaces (alkali‐modified or sandblasted) via resonance frequency analysis (RFA). Materials and Methods Fourteen patients who were bilaterally edentulous in terms of their mandibular molars were enrolled. Implants with alkali‐modified (bioactive) and sandblasted surfaces were randomly placed in either hemi‐arch; the 50 implants used were identical in terms of diameter and length....
Fri Nov 22, 2019 20:29
Objective Piezosurgery, used in different otolaryngology procedures, was a breakthrough in surgery. We systematically reviewed the differences in outcomes after lateral nasal osteotomy with peizosurgery and conventional osteotome and quantified the differences through a meta‐analysis. Methods Medline, Embase, and Cochrane library databases were selected to search for randomized clinical trials (RCTs) published before January 2019 that detailed differences between piezosurgery and conventional...
Fri Nov 22, 2019 19:18
Objectives To determine independent risk factors for 30‐day readmission, prolonged length of stay (PLOS), and discharge to a rehabilitation facility for those with malignant otitis externa. Methods Retrospective cohort study of patients hospitalized with malignant otitis externa (International Classification of Diseases, 9th edition, code 380.14) in the Nationwide Readmissions Database (2013–2014). Overall and disease‐specific complication and mortality data were analyzed using chi‐squared...
Fri Nov 22, 2019 18:48
For the first time, empirical evidence allowed to construct the frequency distribution of an index related to the degree of genetic relatedness between the parents of about 0.5 million humans living in the UK. The results show that a large proportion of the population is not the product of parents choosing a mate randomly. Assortative mating leading to offspring, that occurs between genetic related individuals, is very common. High degrees of genetic relatedness, i.e. extreme inbreeding, is rare....
Sat Nov 23, 2019 02:00
The evolutionary forces shaping life history trait divergence within species are largely unknown. Killifish (oviparous Cyprinodontiformes) evolved an annual life cycle as an exceptional adaptation to life in arid savannah environments characterized by seasonal water availability. The turquoise killifish (Nothobranchius furzeri) is the shortest-lived vertebrate known to science and displays differences in lifespan among wild populations, representing an ideal natural experiment in the evolution and...
Sat Nov 23, 2019 02:00
In standard models of molecular evolution, DNA sequences evolve through asynchronous substitutions according to Poisson processes with a constant rate (called the molecular clock) or a time-varying rate (relaxed clock). However, DNA sequences can also undergo episodes of fast divergence that will appear as synchronous substitutions affecting several sites simultaneously at the macroevolutionary time scale. Here, we develop a model combining basal, clock-like molecular evolution with episodes of fast...
Sat Nov 23, 2019 02:00
The gastrointestinal tract has evolved in numerous ways to allow animals to optimally assimilate energy from different food sources. The morphology and physiology of the gut is plastic and can be greatly altered by diet in some animals. In this study, we investigate the evolution and plasticity of gastrointestinal tract morphology by comparing laboratory raised cave-adapted and river-adapted forms of the Mexican tetra, Astyanax mexicanus reared under different dietary conditions. In the wild, river-dwelling...
Sat Nov 23, 2019 02:00
For the first time, empirical evidence allowed to construct the frequency distribution an index related to the degree of genetic relatedness between the parents from about 500000 humans living in the UK. The results show that a large proportion of the population is not the product of parents choosing a mate randomly. Assortative mating leading to offspring, that occurs between genetic related individuals, is very common. High degrees of genetic relatedness, i.e. extreme inbreeding, is avoided. The...
Sat Nov 23, 2019 02:00
Local adaptation patterns have been found in many plants and animals, highlighting the genetic heterogeneity of species along their range of distribution. In the next decades, global warming must induce a change in the selective pressures that drive this adaptive variation, forcing a reshuffling of the underlying adaptive allele distributions. For species with low dispersion capacity and long generation time such as trees, the rapidity of the change could imped the migration of beneficial alleles...
Sat Nov 23, 2019 02:00
Abstract Purpose This prospective study aimed (1) to assess the non-small cell lung cancer (NSCLC) evolutive patterns to immunotherapy using FDG-PET and (2) to describe their association with clinical outcome. Design Fifty patients with metastatic NSCLC were included before pembrolizumab or nivolumab initiation. FDG-PET scan was performed at baseline and...
Sat Nov 23, 2019 02:00
Publication date: Available online 22 November 2019Source: Radiotherapy and OncologyAuthor(s): Bum-Sup Jang, Wonsik Han, In Ah KimAbstractIntroductionWe analyzed transcriptional and mutational profile mainly focused on tumor mutation burden (TMB), immune checkpoint crosstalk, and radiosensitivity using scRNA-seq data derived from breast cancer and immune cells.Materials and methodsscRNA-seq transcriptome data were acquired from the GEO database (GSE75688). The radiosensitivity index (RSI) was used...
00:57
Publication date: Available online 22 November 2019Source: Radiotherapy and OncologyAuthor(s): Julia Murray, Clare Griffin, Sarah Gulliford, Isabel Syndikus, John Staffurth, Miguel Panades, Christopher Scrase, Chris Parker, Vincent Khoo, Jamie Dean, Helen Mayles, Philip Mayles, Simon Thomas, Olivia Naismith, Angela Baker, Helen Mossop, Clare Cruickshank, Emma Hall, David Dearnaley, on behalf of CHHiP InvestigatorsAbstractBackground and purposeImage-guided radiotherapy (IGRT) improves treatment set-up...
00:57
Publication date: Available online 22 November 2019Source: Radiotherapy and OncologyAuthor(s): Rebecca Bütof, Steffen Löck, Maher Soliman, Robert Haase, Rosalind Perrin, Christian Richter, Steffen Appold, Mechthild Krause, Michael BaumannAbstractBackground and purposeEarly radiation-induced esophageal toxicity (RIET) is one of the major side effects in patients with non-small cell lung cancer (NSCLC) and can be a reason for treatment interruptions. As the age of patients with NSCLC and corresponding...
00:57
Publication date: Available online 22 November 2019Source: Radiotherapy and OncologyAuthor(s): Evelyn E.C. de Jong, Matthias Guckenberger, Nicolaus Andratschke, Karin Dieckmann, Mischa S. Hoogeman, Maaike Milder, Ditte Sloth Møller, Tine Bisballe Nyeng, Stephanie Tanadini-Lang, Eric Lartigau, Thomas Lacornerie, Suresh Senan, Wilko Verbakel, Dirk Verellen, Geert De Kerf, Coen HurkmansAbstractBackground and purposeIn 2017 the ACROP guideline on SBRT for peripherally located early stage NSCLC was published....
00:57
Publication date: Available online 22 November 2019Source: Radiotherapy and OncologyAuthor(s): Judi N.A. van Diessen, Matthew La Fontaine, Michel M. van den Heuvel, Erik van Werkhoven, Iris Walraven, Wouter V. Vogel, José S.A. Belderbos, Jan-Jakob SonkeAbstractBackground and purposeTo investigate associations of early post-treatment 18Fluorodeoxyglucose-positron-emission-tomography (FDG-PET)-scans with local (LF), regional (RF), distant failure (DF) and overall survival (OS) in locally advanced non-small...
00:57
Abstract Neutropenia is one of cancer disease and treatment complications. Suboptimal management of neutropenia may interfere with cancer treatment and result in patient death. This study aimed to evaluate the nurses’ knowledge of neutropenia and their practice for infection prevention in cancer patients in hospitals of Kerman, in southeast Iran. This study had a descriptive-analytical cross-sectional design. 203 nurses working in oncology, bone marrow transplantation, and medical...
Sat Nov 23, 2019 02:00
The aim of the study was to assess the accuracy of commercially available software in estimating anterior tooth root inclination from digital impressions of the crowns of the teeth.
Fri Nov 22, 2019 02:00
Kagami–Ogata syndrome is also known as paternal uniparental disomy 14 and related disorders and is caused by abnormal genomic imprinting in the long arm of the chromosome 14q32.2 region. Its clinical manifesta...
Fri Nov 22, 2019 02:00
The discovery that thoracic horns in dung beetles emerge from the same gene network as wings could revise how biologists understand 'innovation' in nature.
Thu Nov 21, 2019 21:14
Evolution can promote novelty by keeping gene expression in check.
Thu Nov 21, 2019 19:17
Researchers have sequenced the genome of a unique microscopic worm found one mile underground and called the 'Devil Worm' for its ability to survive in harsh, subsurface conditions.
Thu Nov 21, 2019 14:54
Here we present a screening method for membrane-bound pyrophosphatase (from Thermotoga maritima) inhibitors based on the molybdenum blue reaction in a 96 well plate format.
Sat Nov 23, 2019 22:00
Here, we present a protocol to show how to perform two types of cognitive assessment tools derived from the paper-pencil version of the Trail Making Test.
Sat Nov 23, 2019 21:00
This article provides a step-by-step guide to investigate protein subcellular localization dynamics and to monitor morphological changes using high-resolution fluorescence microscopy in Bacillus subtilis and Staphylococcus aureus.
Sat Nov 23, 2019 21:00
We analyzed joint kinematics from four-dimensional computed tomography data. The sequential 3D-3D registration method semiautomatically provides the kinematics of the moving bone with respect to the subject bone from four-dimensional computed tomography data.
Sat Nov 23, 2019 20:00
We performed functional MRI using a novel MRI-compatible hand-induced robotic device to evaluate its utility for monitoring hand motor function in individuals recovering from neurological deficits.
Sat Nov 23, 2019 19:00
Publication date: Available online 22 November 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Koryun Hakobyan, Yuri PoghosyanAbstractKrokodil is a cheap and effective home-made substitute for heroin. It is widely used over the territory of the former USSR (Russia, Ukraine, Armenia and others).Krokodil drug-related midface ON often occurs as a complication of maxillary ON.Treatment of Krokodil drug-related ON of the midface is challenging. It is difficult to determine the ON zone preoperatively...
Sat Nov 23, 2019 22:06
Publication date: Available online 23 November 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Seyit Mehmet Ceylan, İlyas Dişikırık, Mahmut Alper Kanmaz, Altan Yıldırım, Efe SezginAbstractObjectiveThis study aimed to investigate the efficacy of hot posterior nasal packing and hot saline irrigation in bleeding control after adenoidectomy.MethodsA total of 130 patients scheduled for adenoidectomy were included in the study, and randomized into two groups at the beginning...
Sat Nov 23, 2019 21:40
The chemical nanospace confinement effect on the physicochemical properties of host‐guest systems is of pivotal interest to enzyme‐mimicking study. Herein we demonstrate a nanocage coupling effect from a redox Ru(II)‐Pd(II) metal‐organic cage (MOC‐16) for efficient photochemical H 2 production by virtue of redox‐guest modulation of the photo‐induced electron transfer (PET) process. Through coupling with photoredox cycle of MOC‐16, tetrathiafulvalene (TTF) guests act as electron relay mediator to...
Sat Nov 23, 2019 11:28
The first asymmetric Pd(II)‐catalyzed aminofluorination of unactivated alkenes using chiral quinoline‐oxazolines (Quox) as ligand has been developed, which provides an easy access to a wide array of enantiomerically enriched β‐fluoropiperidines in good yields with excellent enantioselectivities. Notably, Et4NF·3HF as a readily accessible nucleophilic fluoride source was found to play an essential role in the enantioselective control, and CsOCF3 also acts an key additive to improve the excellent ee...
Fri Nov 22, 2019 16:59
Informal sector workers are exposed to occupational hazards which could escalate their healthcare expenditures. Thus, enrollment in a health protection scheme among informal sector workers is useful for reduci...
Thu Nov 21, 2019 02:00
Food-borne pathogens are a major cause of illnesses, death and expenses. Their occurrence in meat and other food is considered a global health problem. The burden of food-borne disease is increasing due to ant...
Thu Nov 21, 2019 02:00
Coronary artery disease contributes to noncommunicable disease deaths worldwide. In order to make preventive methods more accurate, we need to know more about the development and progress of this pathology, in...
Thu Nov 21, 2019 02:00
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