Related Articles[Analysis of related factors affecting evolution of recent small subcortical infarcts with cerebral small vessel disease]. Zhonghua Yi Xue Za Zhi. 2019 Nov 19;99(43):3420-3423 Authors: Wang MM, Zhang SS, Liu H, Li YF, Zhao XH Abstract Objective: To explore related factors affecting evolution of recent small subcortical infarct (RSSI) with small-artery occlusion. Methods: A total of 96 RSSI patients with RSSI were admitted from Shanghai...
Sat Nov 23, 2019 13:15
Related Articles[Value of CT in the differential diagnosis of Pseudomonas aeruginosa sinusitis and fungal ball in paranasal sinus caused by Aspergilus flavus]. Zhonghua Yi Xue Za Zhi. 2019 Nov 19;99(43):3417-3419 Authors: Chen XL, Xian JF, Lu XX Abstract Objective: To evaluate the value of CT in the differential diagnosis of Pseudomonas aeruginosa sinusitis and fungal ball in paranasal sinus caused by Aspergilus flavus. Methods: In this retrospective...
Sat Nov 23, 2019 13:15
Related Articles[Application value of motor unit number index in patients with amyotrophic lateral sclerosis]. Zhonghua Yi Xue Za Zhi. 2019 Nov 19;99(43):3413-3416 Authors: Zhang S, Liu XX, Fan DS Abstract Objective: To investigate the application value of motor unit number index (MUNIX) for diagnosis and assessment progress in patients with amyotrophic lateral sclerosis (ALS). Method: Sixty healthy controls and 60 ALS patients in the clinic were enrolled...
Sat Nov 23, 2019 13:15
Related Articles[Incidence and risk factors of ulnar nerve dysfunction after open reduction and internal fixation of humeral intercondylar fractures]. Zhonghua Yi Xue Za Zhi. 2019 Nov 19;99(43):3408-3412 Authors: Liu G, Chen C, Li T, Zha YJ, Gong MQ, Jiang XY Abstract Objective: To investigate the incidence and related risk factors of ulnar nerve dysfunction after open reduction and internal fixation of humeral intercondylar fractures. Methods: A total...
Sat Nov 23, 2019 13:15
Related Articles[Stent placement for filter-related chronic occlusion of the inferior vena cava]. Zhonghua Yi Xue Za Zhi. 2019 Nov 19;99(43):3403-3407 Authors: Zhao BX, He X, Gu JP, Lou WS, Chen L, Gong MF Abstract Objective: To assess the technical success rate, stent patency, clinical efficacy and complications of stent placement for filter-related chronic occlusion of the inferior vena cava. Methods: A retrospective analysis was carried out for 12...
Sat Nov 23, 2019 13:15
Related Articles[New ideas and progress in spinal surgery]. Zhonghua Yi Xue Za Zhi. 2019 Nov 19;99(43):3389-3392 Authors: Gao YZ PMID: 31752466 [PubMed - in process]
Sat Nov 23, 2019 13:15
Related Articles[Development of focused area in orthopedic trauma]. Zhonghua Yi Xue Za Zhi. 2019 Nov 19;99(43):3385-3388 Authors: Wu XB PMID: 31752465 [PubMed - in process]
Sat Nov 23, 2019 13:15
Related Articles[Status and thinking of trauma rescue and treatment system in China]. Zhonghua Yi Xue Za Zhi. 2019 Nov 19;99(43):3382-3384 Authors: Jiang BG PMID: 31752464 [PubMed - in process]
Sat Nov 23, 2019 13:15
Related Articles[Current development and prospect of joint surgery in China]. Zhonghua Yi Xue Za Zhi. 2019 Nov 19;99(43):3378-3381 Authors: Zhang XL, Wang KZ PMID: 31752463 [PubMed - in process]
Sat Nov 23, 2019 13:15
Related Articles[Sequence data analysis andvariant interpretation of next generation sequencing for genetic diseases: problems and challenges]. Zhonghua Yi Xue Za Zhi. 2019 Nov 19;99(43):3372-3377 Authors: Zhang K, Shen YP, Li JM PMID: 31752462 [PubMed - in process]
Sat Nov 23, 2019 13:15
Related Articles[Several hot issues in the detection of plasma EGFR mutations in advanced non-small-cell lung cancer patients]. Zhonghua Yi Xue Za Zhi. 2019 Nov 19;99(43):3364-3371 Authors: Chen YZ, Xu GB, Guan SN, Jia SQ, Kang XZ, Zhao J, Wang GH, Ji JF PMID: 31752461 [PubMed - in process]
Sat Nov 23, 2019 13:15
Related Articles[Pay close attention to standardized application of high-through sequencing in clinic]. Zhonghua Yi Xue Za Zhi. 2019 Nov 19;99(43):3361-3363 Authors: Zhang R, Li JM, Wang QT PMID: 31752460 [PubMed - in process]
Sat Nov 23, 2019 13:15
Related ArticlesInjection laryngoplasty in infants with unilateral vocal cord paralysis: A survey of ASPO members. Int J Pediatr Otorhinolaryngol. 2019 Sep 06;128:109671 Authors: Jang M, Gregory S, Jabbour J, Robey TC, Sulman C, Chun R Abstract INTRODUCTION: Unilateral vocal cord paralysis (UVCP) in infants may be managed medically or surgically, with the latter including injection laryngoplasty (IL). However, there is limited information regarding injection...
Sat Nov 23, 2019 15:15
Related ArticlesDevelopment of auditory perception in preschool children. Int J Pediatr Otorhinolaryngol. 2019 Nov 12;129:109777 Authors: Vilela N, Sanches SGG, Carvallo RMM Abstract OBJECTIVE: The aim of this study was to determine whether the auditory skills presented by five-year-old children can predict their performance in auditory processing (AP) tests at seven years old. DESIGN: Thirty-five children were evaluated for AP at two different...
Sat Nov 23, 2019 15:15
Related ArticlesGeneral anesthesia risk across pediatric surgical specialties: Low in otolaryngology. Int J Pediatr Otorhinolaryngol. 2019 Nov 15;129:109780 Authors: Kolb CM, Tinley-Strong D, Rangarajan R, Uejima T, Shah UK Abstract PURPOSE: To determine the relevance of the Food and Drug Administration (FDA) warning regarding general anesthesia (GA) in children under 3 years of age for procedures lasting longer than 3 h, by surgical specialty and for...
Sat Nov 23, 2019 15:15
Related ArticlesEndoscopic approach to the round window through posterior tympanotomy for cochlear implantation in children: A study on feasibility. Int J Pediatr Otorhinolaryngol. 2019 Nov 15;129:109781 Authors: Nassif N, Redaelli de Zinis LO Abstract OBJECTIVE: To demonstrate the feasibility of rigid endoscopy through posterior tympanotomy, which provides both a view of the round window and direction of the scala tympani in children. METHODS:...
Sat Nov 23, 2019 15:15
Related ArticlesChildhood nontuberculous mycobacterial lymphadenitis-observation alone is a good alternative to surgery. Int J Pediatr Otorhinolaryngol. 2019 Nov 12;129:109778 Authors: Lyly A, Kontturi A, Salo E, Nieminen T, Nokso-Koivisto J Abstract OBJECTIVE: Cervicofacial lymphadenitis caused by nontuberculous mycobacteria (NTM) is commonly treated with surgery or antimicrobial therapy. The aim of this study was to analyze the utility of our new blood-based...
Sat Nov 23, 2019 15:15
Related ArticlesTetramethylpyrazine reduces epileptogenesis progression in electrical kindling models by modulating hippocampal excitatory neurotransmission. ACS Chem Neurosci. 2019 Nov 22;: Authors: Jin Y, Cai S, Jiang Y, Zhong K, Wen C, Ruan Y, Chew LA, Khanna R, Xu Z, Yu J Abstract Antiepileptic drugs (AEDs) are the primary agents prescribed for clinical management of limbic epilepsy. However, high incidence of pharmacoresistance and a limited armory...
Sat Nov 23, 2019 15:04
Related ArticlesOral health status of children with epilepsy in Hong Kong. J Investig Clin Dent. 2019 Nov;10(4):e12479 Authors: Yeung PM, Wong VCN, McGrath CP, Yiu CKY, Lee GHM Abstract AIM: This study assessed and compared the oral health status, dental trauma experience and oral health habits of children with and without epilepsy. METHODS: Thirty-five children with epilepsy aged 3-18 years old were recruited from the pediatric neurology clinics...
Sat Nov 23, 2019 15:04
Related ArticlesLong-term safety and efficacy of lacosamide and controlled-release carbamazepine monotherapy in patients with newly diagnosed epilepsy. Epilepsia. 2019 Nov 21;: Authors: Ben-Menachem E, Grebe HP, Terada K, Jensen L, Li T, De Backer M, Steiniger-Brach B, Gasalla T, Brock M, Biton V Abstract OBJECTIVE: A large-scale, double-blind trial (SP0993; NCT01243177) demonstrated that lacosamide was noninferior to controlled-release carbamazepine...
Sat Nov 23, 2019 13:13
Related ArticlesPrescription Benzodiazepine Use in Privately Insured U.S. Children and Adolescents. Am J Prev Med. 2019 Dec;57(6):775-785 Authors: Bushnell GA, Crystal S, Olfson M Abstract INTRODUCTION: Benzodiazepines are commonly prescribed in the U.S. but entail safety concerns, including dependency. In pediatrics, many indications lack trial data. Authors aimed to describe youth initiating prescription benzodiazepine treatment, identify potential...
Sat Nov 23, 2019 13:13
Related ArticlesEpilepsy and aging. Handb Clin Neurol. 2019;167:455-475 Authors: Kotloski RJ, Dowding J, Hermann BP, Sutula TP Abstract The intersection of epilepsy and aging has broad, significant implications. Substantial increases in seizures occur both in the elderly population, who are at a higher risk of developing new-onset epilepsy, and in those with chronic epilepsy who become aged. There are notable gaps in our understanding of aging and epilepsy...
Sat Nov 23, 2019 13:13
Related ArticlesComparison of zebrafish and mice knockouts for Megalencephalic Leukoencephalopathy proteins indicates that GlialCAM/MLC1 forms a functional unit. Orphanet J Rare Dis. 2019 Nov 21;14(1):268 Authors: Pérez-Rius C, Folgueira M, Elorza-Vidal X, Alia A, Hoegg-Beiler MB, Eeza MNH, Díaz ML, Nunes V, Barrallo-Gimeno A, Estévez R Abstract BACKGROUND: Megalencephalic Leukoencephalopathy with subcortical Cysts (MLC) is a rare type of leukodystrophy...
Sat Nov 23, 2019 13:13
Related ArticlesCarbamazepine Enhances Adipogenesis by Inhibiting Wnt/β-catenin Expression. Cells. 2019 Nov 18;8(11): Authors: Im DU, Kim SC, Chau GC, Um SH Abstract Carbamazepine is a drug that is widely used in the treatment of epilepsy and bipolar disorder. The prevalence of obesity in patients treated with carbamazepine has been frequently reported. However, whether carbamazepine affects adipogenesis, one of the critical steps in the development...
Sat Nov 23, 2019 13:13
Related ArticlesPI3K/mTOR Pathway Inhibition: Opportunities in Oncology and Rare Genetic Diseases. Int J Mol Sci. 2019 Nov 18;20(22): Authors: Hillmann P, Fabbro D Abstract The phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) signaling pathway has been implicated as a cancer target. Big pharma players and small companies have been developing small molecule inhibitors of PI3K and/or mTOR since the 1990s. Although four inhibitors...
Sat Nov 23, 2019 13:13
Related ArticlesPractical aspects of childhood epilepsy. BMJ. 2019 Nov 11;367:l6096 Authors: Petropoulos MC, Bonaiuto K, Currier J, Pal DK PMID: 31712327 [PubMed - indexed for MEDLINE]
Sat Nov 23, 2019 13:13
Related ArticlesWould ivermectin for malaria control be beneficial in onchocerciasis-endemic regions? Infect Dis Poverty. 2019 Aug 23;8(1):77 Authors: Siewe Fodjo JN, Kugler M, Hotterbeekx A, Hendy A, Van Geertruyden JP, Colebunders R Abstract BACKGROUND: There is accumulating evidence supporting the use of ivermectin as a malaria control tool. Recent findings from the repeat ivermectin mass drug administrations for control of malaria trial demonstrated...
Sat Nov 23, 2019 13:13
Related ArticlesThe Projected Care Trajectory for Persons with Epilepsy. Nurs Clin North Am. 2019 09;54(3):425-435 Authors: Miller WR Abstract Epilepsy is a complex neurologic disease that requires both medical management and self-management. People with epilepsy and their families complete many transitions throughout the health care system in managing this disease. This article reviews key transitions for people with epilepsy and discusses strategies...
Sat Nov 23, 2019 13:13
Related ArticlesBone microstructure and metabolism changes under the combined intervention of ketogenic diet with intermittent fasting: an in vivo study of rats. Exp Anim. 2019 Aug 14;68(3):371-380 Authors: Xu X, Ding J, Wu X, Huang Z, Kong G, Liu Q, Yang Z, Huang Z, Zhu Q Abstract Ketogenic diet (KD) has been used in epilepsy for decades, but previous studies found it may cause severe bone loss. Every-other-day ketogenic diet (EODKD), the combination...
Sat Nov 23, 2019 13:13
Related ArticlesPrognostic value of risk stratification using blood parameters for nivolumab in Japanese patients with metastatic renal-cell carcinoma. Jpn J Clin Oncol. 2019 Nov 22;: Authors: Yamamoto Y, Matsuyama H, Matsumoto H, Sakano S, Fuji N, Oba K, Yamamoto M, Kamiryo Y, Hiragino T, Nagao K, Takai K, Aoki A Abstract BACKGROUND: Nivolumab is a standard treatment for previously treated advanced renal-cell carcinoma. However, nivolumab is effective...
Sat Nov 23, 2019 15:15
Publication date: Available online 22 November 2019Source: Magnetic Resonance ImagingAuthor(s): Kellsie Shan, Yunsuo DuanAbstractThe Design accuracy of MRI system with dual-tuned four-ring birdcage coils remains challenging due to inter-coil interference that tends to deteriorate signal-to-noise ratio and thus image quality. In this study, we develop an accurate and efficient FEM modeling strategy by optimizing model geometries, meshing density, and boundary conditions in accord with the correlated...
Sat Nov 23, 2019 13:11
Abstract Introduction We investigated multi-domain baseline neurocognition of primary brain tumor patients prior to radiotherapy (RT), including clinical predictors of function and association between pre-RT and post-RT impairment on a prospective trial. Methods A multi-domain neuropsychological battery (memory, executive functioning, language, attention,...
Sat Nov 23, 2019 02:00
AbstractTaste signals food quality and reflects energy status and associated processes. Occidental High- and Low-Saccharin Consuming Rats (HiS, LoS) have been selectively bred for nearly sixty generations on intake of 0.1% saccharin in a 23-h two-bottle test, as a tool for studying individual differences in taste and its correlates in the domains of feeding, defensive, and social behavior. The saccharin phenotype itself has not been well characterized until now. The present series of parametric studies...
Sat Nov 23, 2019 02:00
Related ArticlesBrigatinib in Crizotinib-Refractory ALK+ Non-Small Cell Lung Cancer: 2-Year Follow-up on Systemic and Intracranial Outcomes in the Phase 2 ALTA Trial. J Thorac Oncol. 2019 Nov 19;: Authors: Huber RM, Hansen KH, Paz-Ares Rodríguez L, West HL, Reckamp KL, Leighl NB, Tiseo M, Smit EF, Kim DW, Gettinger SN, Hochmair MJ, Kim SW, Langer CJ, Ahn MJ, Kim ES, Kerstein D, Groen HJM, Camidge DR Abstract INTRODUCTION: We report updated data from...
Sat Nov 23, 2019 15:04
Related Articles5-fluorouracil and other fluoropyrimidines in colorectal cancer: Past, present and future. Pharmacol Ther. 2019 Nov 19;:107447 Authors: Vodenkova S, Buchler T, Cervena K, Veskrnova V, Vodicka P, Vymetalkova V Abstract 5-Fluorouracil (5-FU) is an essential component of systemic chemotherapy for colorectal cancer (CRC) in the palliative and adjuvant settings. Over the past four decades, several modulation strategies including the implementation...
Sat Nov 23, 2019 15:04
Related ArticlesIdentifying and Treating Refractory ITP: Difficulty in Diagnosis and Role of Combination Treatment. Blood. 2019 Nov 22;: Authors: Miltiadous O, Hou M, Bussel JB Abstract Immune Thrombocytopenia (ITP) is the commonest acquired thrombocytopenia after chemotherapy-induced thrombocytopenia. Existing guidelines describe the management and treatment of most patients who overall do well, even if they present with chronic disease, and are usually...
Sat Nov 23, 2019 15:04
Related ArticlesChemical Proteomics and Phenotypic Profiling Identifies the Aryl Hydrocarbon Receptor as a Molecular Target of the Utrophin Modulator Ezutromid. Angew Chem Int Ed Engl. 2019 Nov 22;: Authors: Wilkinson IVL, Perkins KJ, Dugdale H, Moir L, Vuorinen A, Chatzopoulou M, Squire SE, Monecke S, Lomow A, Geese M, Charles PD, Burch P, Tinsley JM, Wynne GM, Davies SG, Wilson FX, Rastinejad F, Mohammed S, Davies KE, Russell AJ Abstract Duchenne muscular...
Sat Nov 23, 2019 15:04
Related ArticlesA Retrospective Look at Anti-EGFR Agents in Pancreatic Cancer Therapy. Curr Drug Metab. 2019 Nov 21;: Authors: Verma HK, Kampalli PK, Lakkakula S, Chalikonda G, Lakkakula BVKS, Pattnaik S Abstract BACKGROUND: The introduction of Monoclonal Antibodies (mAbs) and small molecule Tyrosine Kinase Inhibitors (TKIs) that target the Epidermal Growth Factor Receptor (EGFR), mark a huge step forward in the Pancreatic Cancer (PC) therapy. However,...
Sat Nov 23, 2019 15:04
Related ArticlesIntrigue: Phase III study of ripretinib versus sunitinib in advanced gastrointestinal stromal tumor after imatinib. Future Oncol. 2019 Nov 22;: Authors: Nemunaitis J, Bauer S, Blay JY, Choucair K, Gelderblom H, George S, Schöffski P, Mehren MV, Zalcberg J, Achour H, Ruiz-Soto R, Heinrich MC Abstract Ripretinib (DCC-2618) is a novel, type II tyrosine switch control inhibitor designed to broadly inhibit activating and drug-resistant mutations...
Sat Nov 23, 2019 15:04
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