Antibiotics, Vol. 8, Pages 162: Natural Product Type III Secretion System Inhibitors Antibiotics doi: 10.3390/antibiotics8040162 Authors: Heather A. Pendergrass Aaron E. May Many known inhibitors of the bacterial type III secretion system (T3SS), a virulence factor used by pathogenic bacteria to infect host cells, are natural products. These compounds, produced by bacteria, fungi, and plants, may have developed as prophylactic treatments for potential attack by bacterial pathogens...
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Antibiotics, Vol. 8, Pages 161: HBD3 Induces PD-L1 Expression on Head and Neck Squamous Cell Carcinoma Cell Lines Antibiotics doi: 10.3390/antibiotics8040161 Authors: Maria Paula Gomez Hernandez Amber M. Bates Emily E. Starman Emily A. Lanzel Carissa Comnick Xian Jin Xie Kim A. Brogden Human β-defensin 3 (HBD3) is an antimicrobial peptide up-regulated in the oral tissues of individuals with head and neck squamous cell carcinomas (HNSCC) and oral squamous cell carcinomas...
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Antibodies, Vol. 8, Pages 48: Distinguishing Between Monomeric scFv and Diabody in Solution Using Light and Small Angle X-ray Scattering Antibodies doi: 10.3390/antib8040048 Authors: Frank Lüdel Sandra Bufe Willem M. Bleymüller Hugo de de Jonge Luisa Iamele Hartmut H. Niemann Thomas Hellweg Depending on the linker length between the V H and the V L domain, single-chain Fv (scFv) antibody fragments form monomers, dimers (diabodies) or higher oligomers....
Mon Sep 23, 2019 03:00
Antioxidants, Vol. 8, Pages 425: Ultrasound-Assisted Extraction of Total Flavonoids from Pteris cretica L.: Process Optimization, HPLC Analysis, and Evaluation of Antioxidant Activity Antioxidants doi: 10.3390/antiox8100425 Authors: Mengyang Hou Wenzhong Hu Aosheng Wang Zhilong Xiu Yusheng Shi Kexin Hao Xingsheng Sun Duo Cao Ruishan Lu Jiao Sun In the present work, the ultrasonic-assisted extraction (UAE) of total flavonoids (TF) from Pteris cretica L. was...
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Atmosphere, Vol. 10, Pages 574: Heavy Rainfall Events in Southern China Associated with Tropical Cyclones in the Bay of Bengal: A Case Study Atmosphere doi: 10.3390/atmos10100574 Authors: Junpeng Yuan Jiao Lü Dian Feng Mengni Mao Tao Feng Juyue Yin Ling Zuo We use a case study to show that a continuous heavy rainfall process in southern China was closely related to tropical cyclone activity in the Bay of Bengal. The continuous heavy rainfall that occurred in southern...
Mon Sep 23, 2019 03:00
Atmosphere, Vol. 10, Pages 573: Trace Metal Content and Health Risk Assessment of PM10 in an Urban Environment of León, Mexico Atmosphere doi: 10.3390/atmos10100573 Authors: Julia Griselda Cerón Bretón Rosa María Cerón Bretón Alberto Antonio Espinosa Guzman Claudio Guarnaccia Stephanie Martínez Morales Reyna del Carmen Lara Severino Marcela Rangel Marrón Guadalupe Hernández López Simón Eduardo Carranco Lozada Jonathan D.W. Kahl Ildefonso Esteban Pech Pech Evangelina...
Mon Sep 23, 2019 03:00
Biology, Vol. 8, Pages 70: Extraction, Storage Duration, and Storage Temperature Affect the Activity of Ascorbate Peroxidase, Glutathione Reductase, and Superoxide Dismutase in Rice Tissue Biology doi: 10.3390/biology8040070 Authors: Julia Hartmann Folkard Asch In experimental plant science, research often faces large numbers of tissue samples resulting from sequential harvests of a larger number of genotypes and treatments combinations. Analyses of biological processes such as enzyme...
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Biomolecules, Vol. 9, Pages 524: The Prevalence, Antibiotic Resistance and Biofilm Formation of Staphylococcus aureus in Bulk Ready-To-Eat Foods Biomolecules doi: 10.3390/biom9100524 Authors: Lin Sun Yao Cai Ren Chi The prevalence of Staphylococcus aureus in 2160 bulk ready-to-eat foods from the Sichuan province of China during 2013–2016 was investigated. The antibiotic resistance and the associated genes, as well as biofilm formation capacity of the S....
Mon Sep 23, 2019 03:00
Biomolecules, Vol. 9, Pages 523: Combination of Transcriptomic, Proteomic, and Metabolomic Analysis Reveals the Ripening Mechanism of Banana Pulp Biomolecules doi: 10.3390/biom9100523 Authors: Li Yun Wu Qu Duan Jiang The banana is one of the most important fruits in the world. Bananas undergo a rapid ripening process after harvest, resulting in a short shelf. In this study, the mechanism underlying pulp ripening of harvested bananas was investigated using integrated...
Mon Sep 23, 2019 03:00
Biomolecules, Vol. 9, Pages 522: New Insights into Structural and Functional Roles of Indole-3-acetic acid (IAA): Changes in DNA Topology and Gene Expression in Bacteria Biomolecules doi: 10.3390/biom9100522 Authors: Defez Valenti Andreozzi Romano Ciaramella Pesaresi Forlani Bianco : Indole-3-acetic acid (IAA) is a major plant hormone that affects many cellular processes in plants, bacteria, yeast, and human cells through still unknown mechanisms. In this...
Mon Sep 23, 2019 03:00
Cancers, Vol. 11, Pages 1417: Quality of Response in Acute Myeloid Leukemia: The Role of Minimal Residual Disease Cancers doi: 10.3390/cancers11101417 Authors: Maurillo Bassan Cascavilla Ciceri : In the acute myeloid leukemia (AML) setting, research has extensively investigated the existence and relevance of molecular biomarkers, in order to better tailor therapy with newly developed agents and hence improve outcomes and/or save the patient from poorly effective therapies....
Mon Sep 23, 2019 03:00
Cancers, Vol. 11, Pages 1418: Estrogen Receptors in Epithelial-Mesenchymal Transition of Prostate Cancer Cancers doi: 10.3390/cancers11101418 Authors: Di Zazzo Galasso Giovannelli Di Donato Bilancio Perillo Sinisi Migliaccio Castoria Prostate cancer (PC) remains a widespread malignancy in men. Since the androgen/androgen receptor (AR) axis is associated with the pathogenesis of prostate cancer, suppression of AR-dependent signaling by androgen deprivation...
Mon Sep 23, 2019 03:00
Cells, Vol. 8, Pages 1131: Inflammasome-Mediated Inflammation in Liver Ischemia-Reperfusion Injury Cells doi: 10.3390/cells8101131 Authors: Mónica B. Jiménez-Castro María Eugenia Cornide-Petronio Jordi Gracia-Sancho Carmen Peralta Ischemia-reperfusion injury is an important cause of liver damage occurring during surgical procedures including hepatic resection and liver transplantation, and represents the main underlying cause of graft dysfunction and liver failure post-transplantation....
Mon Sep 23, 2019 03:00
Cells, Vol. 8, Pages 1132: Roles of Resveratrol in Improving the Quality of Postovulatory Aging Oocytes In Vitro Cells doi: 10.3390/cells8101132 Authors: Yan-Li Sun Shou-Bin Tang Wei Shen Shen Yin Qing-Yuan Sun After ovulation, mammalian oocytes will undergo a time-dependent process of aging if they are not fertilized. This postovulatory aging (POA) seriously affects the oocyte quality and then impairs the subsequent fertilization and early embryo development, which should...
Mon Sep 23, 2019 03:00
Cells, Vol. 8, Pages 1130: The Interactivity between TGFβ and BMP Signaling in Organogenesis, Fibrosis, and Cancer Cells doi: 10.3390/cells8101130 Authors: Francesco Dituri Carla Cossu Serena Mancarella Gianluigi Giannelli The Transforming Growth Factor beta (TGFβ) and Bone Morphogenic Protein (BMP) pathways intersect at multiple signaling hubs and cooperatively or counteractively participate to bring about cellular processes which are critical not only for tissue morphogenesis...
Mon Sep 23, 2019 03:00
Diagnostics, Vol. 9, Pages 126: Association Between VEGF Expression and Diffusion Weighted Imaging in Several Tumors—A Systematic Review and Meta-Analysis Diagnostics doi: 10.3390/diagnostics9040126 Authors: Hans-Jonas Meyer Andreas Wienke Alexey Surov To date, only a few studies have investigated relationships between Diffusion-weighted imaging (DWI) and Vascular endothelial growth factor (VEGF) expression in tumors. The reported results are contradictory. The aim of the present...
Mon Sep 23, 2019 03:00
Foods, Vol. 8, Pages 434: Overview of Foodborne Disease Outbreaks in Brazil from 2000 to 2018 Foods doi: 10.3390/foods8100434 Authors: Jéssica A. F. F. Finger Wilma S. G. V. Baroni Daniele F. Maffei Deborah H. M. Bastos Uelinton M. Pinto This study aimed to assess the foodborne diseases (FBD) outbreaks reported in Brazil between 2000 and 2018, based on data from the Brazilian Ministry of Health (official data) and from scientific literature. According to official data, 13,163...
Mon Sep 23, 2019 03:00
Humanities, Vol. 8, Pages 154: The Rhetoric of Krishna versus the Counter-Rhetoric of Vyas: The Place of Commiseration in the Mahabharat Humanities doi: 10.3390/h8040154 Authors: Bhushan Aryal In the context of the mixed perception among scholars whether the Mahabharat is a pacifist or a militant text, this paper analyzes the rhetorical project of the epic to examine its position on violence. Highlighting the existence of two main arguments in the Mahabharat, this paper argues that the...
Mon Sep 23, 2019 03:00
IJERPH, Vol. 16, Pages 3563: A Qualitative Study Examining Parental Involvement in Youth Sports over a One-Year Intervention Program International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16193563 Authors: Ausra Lisinskiene Marc Lochbaum The purpose of this 12-month intervention program was to examine parent–child relationship changes within the sports context. A qualitative interpretative phenomenological analysis was used for the study design....
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IJERPH, Vol. 16, Pages 3561: Quality of Life and Associated Factors among Primary Care Asian Patients with Type 2 Diabetes Mellitus International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16193561 Authors: Hardesh Dhillon Rusli Bin Nordin Amutha Ramadas Diabetes complications, medication adherence, and psychosocial well-being have been associated with quality of life (QOL) among several Western and Asian populations with diabetes, however, there is...
Mon Sep 23, 2019 03:00
IJERPH, Vol. 16, Pages 3560: Drama Therapy Counseling as Mental Health Care of College Students International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16193560 Authors: Wen-Lung Chang Yu-Shiuan Liu Cheng-Fu Yang (1) Background: This study aims to apply drama therapy to a counseling group to address the mental health problems of college students in Taiwan due to the increasingly serious psychological problems that have happened in recent times. Based...
Mon Sep 23, 2019 03:00
IJERPH, Vol. 16, Pages 3559: Geochemical Evidence of Metal-Driven Anaerobic Oxidation of Methane in the Shenhu Area, the South China Sea International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16193559 Authors: Rui Xie Daidai Wu Jie Liu Tiantian Sun Lihua Liu Nengyou Wu Anaerobic oxidation of methane (AOM) is a common biochemical process in the ocean and it plays an important role in global climate change, elemental circulation, and atmospheric...
Mon Sep 23, 2019 03:00
IJERPH, Vol. 16, Pages 3558: Associations between Specialist Tactical Response Police Unit Selection Success and Urban Rush, along with 2.4 km and 10 km Loaded Carriage Events International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16193558 Authors: Rhiannon Thomas Ben Schram Shane Irving Jeremy Robinson Robin Orr Officers serving in specialist tactical response police teams are highly trained personnel who are required to carry heavy loads and...
Mon Sep 23, 2019 03:00
IJMS, Vol. 20, Pages 4726: Proteomics of PTI and Two ETI Immune Reactions in Potato Leaves International Journal of Molecular Sciences doi: 10.3390/ijms20194726 Authors: Svante Resjö Muhammad Awais Zahid Dharani Dhar Burra Marit Lenman Fredrik Levander Erik Andreasson Plants have a variety of ways to defend themselves against pathogens. A commonly used model of the plant immune system is divided into a general response triggered by pathogen-associated molecular patterns...
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IJMS, Vol. 20, Pages 4725: Comparative Proteomics of Salt-Tolerant and Salt-Sensitive Maize Inbred Lines to Reveal the Molecular Mechanism of Salt Tolerance International Journal of Molecular Sciences doi: 10.3390/ijms20194725 Authors: Fenqi Chen Peng Fang Yunling Peng Wenjing Zeng Xiaoqiang Zhao Yongfu Ding Zelong Zhuang Qiaohong Gao Bin Ren Salt stress is one of the key abiotic stresses that causes great loss of yield and serious decrease in quality in maize...
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IJMS, Vol. 20, Pages 4724: A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer’s Disease International Journal of Molecular Sciences doi: 10.3390/ijms20194724 Authors: Gustavo Provensi Fabrizio Carta Alessio Nocentini Claudiu T. Supuran Fiorella Casamenti M. Beatrice Passani Silvia Fossati The increase in the incidence of neurodegenerative diseases, in particular Alzheimer’s Disease (AD), is a consequence of the world′s...
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IJMS, Vol. 20, Pages 4723: DNA Copy Number Variations as Markers of Mutagenic Impact International Journal of Molecular Sciences doi: 10.3390/ijms20194723 Authors: Galina Hovhannisyan Tigran Harutyunyan Rouben Aroutiounian Thomas Liehr DNA copy number variation (CNV) occurs due to deletion or duplication of DNA segments resulting in a different number of copies of a specific DNA-stretch on homologous chromosomes. Implications of CNVs in evolution and development of different...
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IJMS, Vol. 20, Pages 4722: Overexpression of BpCUC2 Influences Leaf Shape and Internode Development in Betula pendula International Journal of Molecular Sciences doi: 10.3390/ijms20194722 Authors: Liu Xu Han Wang Liu Chen Chen Bian Jiang The CUP-SHAPED COTYLEDON 2 (CUC2) gene, which is negatively regulated by microRNA164 (miR164), has been specifically linked to the regulation of leaf margin serration and the maintenance of phyllotaxy in model plants....
Mon Sep 23, 2019 03:00
IJMS, Vol. 20, Pages 4720: Ovarian Follicle Depletion Induced by Chemotherapy and the Investigational Stages of Potential Fertility-Protective Treatments—A Review International Journal of Molecular Sciences doi: 10.3390/ijms20194720 Authors: Xia Hao Amandine Anastácio Kui Liu Kenny A. Rodriguez-Wallberg Ovarian follicle pool depletion, infertility, and premature menopause are all known sequelae of cancer treatment that negatively impact the quality of life of young cancer survivors....
Mon Sep 23, 2019 03:00
IJMS, Vol. 20, Pages 4721: Investigation of Phospholipase Cγ1 Interaction with SLP76 Using Molecular Modeling Methods for Identifying Novel Inhibitors International Journal of Molecular Sciences doi: 10.3390/ijms20194721 Authors: Tripathi Vetrivel Téletchéa Jean Legembre Laurent The enzyme phospholipase C gamma 1 (PLCγ1) has been identified as a potential drug target of interest for various pathological conditions such as immune disorders, systemic lupus...
Mon Sep 23, 2019 03:00
IJMS, Vol. 20, Pages 4718: Advances Towards How Meiotic Recombination Is Initiated: A Comparative View and Perspectives for Plant Meiosis Research International Journal of Molecular Sciences doi: 10.3390/ijms20194718 Authors: Ju-Li Jing Ting Zhang Ya-Zhong Wang Yan He Meiosis is an essential cell-division process for ensuring genetic diversity across generations. Meiotic recombination ensures the accuracy of genetic interchange between homolous chromosomes and segregation of...
Mon Sep 23, 2019 03:00
IJMS, Vol. 20, Pages 4719: Latest Advances in Targeting the Tumor Microenvironment for Tumor Suppression International Journal of Molecular Sciences doi: 10.3390/ijms20194719 Authors: Chloé Laplagne Marcin Domagala Augustin Le Naour Christophe Quemerais Dimitri Hamel Jean-Jacques Fournié Bettina Couderc Corinne Bousquet Audrey Ferrand Mary Poupot The tumor bulk is composed of a highly heterogeneous population of cancer cells, as well as a large variety of resident...
Mon Sep 23, 2019 03:00
IJMS, Vol. 20, Pages 4717: Effects of Extract of Arrabidaea chica Verlot on an Experimental Model of Osteoarthritis International Journal of Molecular Sciences doi: 10.3390/ijms20194717 Authors: Cleydlenne Costa Vasconcelos Alberto Jorge Oliveira Lopes Emerson Lucas Frazão Sousa Darleno Sousa Camelo Fernando César Vilhena Moreira Lima Cláudia Quintino da Rocha Gyl Eanes Barros Silva João Batista Santos Garcia Maria do Socorro de Sousa Cartágenes The aim of this...
Mon Sep 23, 2019 03:00
IJMS, Vol. 20, Pages 4715: Rice Bran Phenolic Compounds Regulate Genes Associated with Antioxidant and Anti-Inflammatory Activity in Human Umbilical Vein Endothelial Cells with Induced Oxidative Stress International Journal of Molecular Sciences doi: 10.3390/ijms20194715 Authors: Nancy Saji Nidhish Francis Christopher L. Blanchard Lachlan J. Schwarz Abishek B. Santhakumar Oxidative stress, inflammation and endothelial dysfunction are associated with the development of cardiovascular...
Mon Sep 23, 2019 03:00
IJMS, Vol. 20, Pages 4714: MicroRNAs in Cardiac Hypertrophy International Journal of Molecular Sciences doi: 10.3390/ijms20194714 Authors: Nadine Wehbe Suzanne Awani Nasser Gianfranco Pintus Adnan Badran Ali H. Eid Elias Baydoun Like other organs, the heart undergoes normal adaptive remodeling, such as cardiac hypertrophy, with age. This remodeling, however, is intensified under stress and pathological conditions. Cardiac remodeling could be beneficial for a short period...
Mon Sep 23, 2019 03:00
IJMS, Vol. 20, Pages 4716: Metabolic and Vascular Effect of the Mediterranean Diet International Journal of Molecular Sciences doi: 10.3390/ijms20194716 Authors: Antonino Tuttolomondo Irene Simonetta Mario Daidone Alba Mogavero Antonella Ortello Antonio Pinto Several studies indicated how dietary patterns that were obtained from nutritional cluster analysis can predict disease risk or mortality. Low-grade chronic inflammation represents a background pathogenetic mechanism...
Mon Sep 23, 2019 03:00
IJMS, Vol. 20, Pages 4712: Drug-Induced Hypertension Caused by Multikinase Inhibitors (Sorafenib, Sunitinib, Lenvatinib and Axitinib) in Renal Cell Carcinoma Treatment International Journal of Molecular Sciences doi: 10.3390/ijms20194712 Authors: Nanna Bæk Møller Cecilie Budolfsen Daniela Grimm Marcus Krüger Manfred Infanger Markus Wehland Nils E. Magnusson This paper reviews current treatments for renal cell carcinoma/cancer (RCC) with the multikinase inhibitors (MKIs)...
Mon Sep 23, 2019 03:00
IJMS, Vol. 20, Pages 4713: Regulation of Heat Shock Factor Pathways by γ-aminobutyric Acid (GABA) Associated with Thermotolerance of Creeping Bentgrass International Journal of Molecular Sciences doi: 10.3390/ijms20194713 Authors: Ting Liu Zhaoqiao Liu Zhou Li Yan Peng Xinquan Zhang Xiao Ma Linkai Huang Wei Liu Gang Nie Liwen He Activation and enhancement of heat shock factor (HSF) pathways are important adaptive responses to heat stress in plants. The γ-aminobutyric...
Mon Sep 23, 2019 03:00
IJMS, Vol. 20, Pages 4711: Cytogenetics and Cytogenomics Evaluation in Cancer International Journal of Molecular Sciences doi: 10.3390/ijms20194711 Authors: Ilda Patrícia Ribeiro Joana Barbosa Melo Isabel Marques Carreira The availability of cytogenetics and cytogenomics technologies improved the detection and identification of tumor molecular signatures as well as the understanding of cancer initiation and progression. The use of large-scale and high-throughput cytogenomics technologies...
Mon Sep 23, 2019 03:00
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