Antibiotics, Vol. 8, Pages 141: Epidemiological Characteristics of Staphylococcus Aureus in Raw Goat Milk in Shaanxi Province, China Antibiotics doi: 10.3390/antibiotics8030141 Authors: Weidong Qian Lanfang Shen Xinchen Li Ting Wang Miao Liu Wenjing Wang Yuting Fu Qiao Zeng Goat milk has been frequently implicated in staphylococcal food poisoning. The potential risk of raw goat milk contaminated by Staphylococcus aureus (S. aureus) in Shaanxi province of China is...
Sun Sep 08, 2019 03:00
Antibodies, Vol. 8, Pages 46: Optimization of an Antibody Light Chain Framework Enhances Expression, Biophysical Properties and Pharmacokinetics Antibodies doi: 10.3390/antib8030046 Authors: Patrice Douillard Michael Freissmuth Gerhard Antoine Michael Thiele Daniel Fleischanderl Peter Matthiessen Dirk Voelkel Randolf J. Kerschbaumer Friedrich Scheiflinger Nicolas Sabarth Efficacy, safety, and manufacturability of therapeutic antibodies are influenced by their...
Fri Sep 06, 2019 03:00
Antioxidants, Vol. 8, Pages 381: Antioxidant Effects of Apocynum venetum Tea Extracts on d-Galactose-Induced Aging Model in Mice Antioxidants doi: 10.3390/antiox8090381 Authors: Chong Li Fang Tan Jianjun Yang Yue Yang Yuting Gou Shuting Li Xin Zhao As a traditional Chinese medicinal drink, Apocynum venetum, a local tea from Xinjiang, China, is favored for its rich flavor and biological functionality. This study looked at aging mice induced by d-galactose to determine...
Sun Sep 08, 2019 03:00
Antioxidants, Vol. 8, Pages 380: Recovery of Polyphenols from Brewer’s Spent Grains Antioxidants doi: 10.3390/antiox8090380 Authors: Rares I. Birsan Peter Wilde Keith W. Waldron Dilip K. Rai The recovery of antioxidant polyphenols from light, dark and mix brewer’s spent grain (BSG) using conventional maceration, microwave and ultrasound assisted extraction was investigated. Total polyphenols were measured in the crude (60% acetone), liquor extracts (saponified with...
Sat Sep 07, 2019 03:00
Antioxidants, Vol. 8, Pages 379: Can Plant Phenolic Compounds Protect the Skin from Airborne Particulate Matter? Antioxidants doi: 10.3390/antiox8090379 Authors: Yong Chool Boo The skin is directly exposed to the polluted atmospheric environment, and skin diseases, such as atopic dermatitis and acne vulgaris, can be induced or exacerbated by airborne particulate matter (PM). PM can also promote premature skin aging with its accompanying functional and morphological changes. PM-induced...
Fri Sep 06, 2019 03:00
Antioxidants, Vol. 8, Pages 378: Analysis of Oxidative Stress-Related Markers in Crohn’s Disease Patients at Surgery and Correlations with Clinical Findings Antioxidants doi: 10.3390/antiox8090378 Authors: Cristina Luceri Elisabetta Bigagli Sara Agostiniani Francesco Giudici Daniela Zambonin Stefano Scaringi Ferdinando Ficari Maura Lodovici Cecilia Malentacchi Crohn’ disease (CD) patients are at high risk of postoperative recurrence and new tools for...
Fri Sep 06, 2019 03:00
Atmosphere, Vol. 10, Pages 529: Recent Trends in Maintenance Costs for Façades Due to Air Pollution in the Oslo Quadrature, Norway Atmosphere doi: 10.3390/atmos10090529 Authors: Grøntoft This study assesses changes since 1980 in the maintenance cost of the façades of the historical 17th to 19th century buildings of the Oslo Quadrature, Norway, due to atmospheric chemical wear, including the influence of air pollution. Bottom up estimations by exposure–response...
Sun Sep 08, 2019 03:00
Atmosphere, Vol. 10, Pages 528: Seasonal Forecasting of the Onset of the Rainy Season in West Africa
Atmosphere, Vol. 10, Pages 528: Seasonal Forecasting of the Onset of the Rainy Season in West Africa Atmosphere doi: 10.3390/atmos10090528 Authors: Manuel Rauch Jan Bliefernicht Patrick Laux Seyni Salack Moussa Waongo Harald Kunstmann Seasonal forecasts for monsoonal rainfall characteristics like the onset of the rainy seasons (ORS) are crucial for national weather services in semi-arid regions to better support decision-making in rain-fed agriculture. In this study an...
Sun Sep 08, 2019 03:00
Atmosphere, Vol. 10, Pages 527: The Role of Background Wind and Moisture in the Atmospheric Response to Oceanic Eddies During Winter in the Kuroshio Extension Region Atmosphere doi: 10.3390/atmos10090527 Authors: Yinglai Jia Longjing Chen Qinyu Liu Xiaohui Yang Yifei Wu The role of background wind and moisture in the atmospheric response to oceanic eddies during winter in the Kuroshio Extension (KE) region is examined by numerical experiments (EXPs) using the Weather Research...
Sat Sep 07, 2019 03:00
Atmosphere, Vol. 10, Pages 526: GIS Application for Determining Geographical Factors on Intensity of Erosion in Serbian River Basins. Case Study: The River Basin of Likodra Atmosphere doi: 10.3390/atmos10090526 Authors: Branko Ristanović Marija Cimbaljević Đurđa Miljković Miloš Ostojić Renata Fekete Inadequate management of water resources may generate various potential geohazard risks. To resolve potential risks, significant anthropogenic factors need to be engaged, such...
Fri Sep 06, 2019 03:00
Atmosphere, Vol. 10, Pages 525: Reduction of Bioaerosols Emitted from a Swine Confinement Building by a Percolating Biofilter During a 10-Month Period Atmosphere doi: 10.3390/atmos10090525 Authors: Jonathan Vyskocil Valérie Létourneau Matthieu Girard Ariane Lévesque Caroline Duchaine The release of pathogens into the air from swine confinement buildings are mitigated through preventative measures, such as outgoing air filtration, to reduce the risk of spread to nearby barns...
Fri Sep 06, 2019 03:00
Atmosphere, Vol. 10, Pages 524: Olfactory Characterization of Typical Odorous Pollutants Part I: Relationship Between the Hedonic Tone and Odor Concentration Atmosphere doi: 10.3390/atmos10090524 Authors: Jiayin Li Kehua Zou Weifang Li Gen Wang Weihua Yang The hedonic tone is a suitable evaluation index which can truly reflect the psychological impact of an odor. To find out the relationship between the odor concentration (OC) and hedonic tone (H), dimethyl disulfide, limonene...
Fri Sep 06, 2019 03:00
Beverages, Vol. 5, Pages 57: Modelling Changes in Volatile Compounds in British Columbian Varietal Wines that Were Bottle Aged for Up to 120 Months Beverages doi: 10.3390/beverages5030057 Authors: Bejaei Cliff Madilao vanVuuren This research quantified 46 volatile compounds in vintage wines (1998–2005) from British Columbia (BC), which had been bottle-aged for up to 120 months. Wines were analyzed up to five times, between December 2003 and October 2008. Compounds...
Fri Sep 06, 2019 03:00
Bioengineering, Vol. 6, Pages 80: Comparison of Dry Versus Wet Milling to Improve Bioethanol or Methane Recovery from Solid Anaerobic Digestate Bioengineering doi: 10.3390/bioengineering6030080 Authors: Monlau Sambusiti barakat Biogas plants for waste treatment valorization are presently experiencing rapid development, especially in the agricultural sector, where large amounts of digestate are being generated. In this study, we investigated the effect of vibro-ball milling (VBM)...
Fri Sep 06, 2019 03:00
Bioengineering, Vol. 6, Pages 79: Extracellular Vesicles: From Biology to Biomedical Applications Bioengineering doi: 10.3390/bioengineering6030079 Authors: Esther Serrano-Pertierra Maria Carmen Blanco-López Legend says that Philippides ran to Athens to announce the victory against the Persians in the Battle of Marathon [...]
Fri Sep 06, 2019 03:00
Biomimetics, Vol. 4, Pages 63: Design of a Bio-Inspired Anti-Erosion Structure for a Water Hydraulic Valve Core: An Experimental Study Biomimetics doi: 10.3390/biomimetics4030063 Authors: Haihang Wang He Xu Yonghui Zhang Siqing Chen Zitong Zhao Junlong Chen Animals and plants have numerous active protections for adapting to the complex and severe living environments, providing endless inspiration for extending the service life of materials and machines. Conch, a marine...
Fri Sep 06, 2019 03:00
Biomolecules, Vol. 9, Pages 461: Improved Cordycepin Production by Cordyceps militaris KYL05 Using Casein Hydrolysate in Submerged Conditions Biomolecules doi: 10.3390/biom9090461 Authors: Soo Kweon Lee Ju Hun Lee Hyeong Ryeol Kim Youngsang Chun Ja Hyun Lee Hah Young Yoo Chulhwan Park Seung Wook Kim Cordycepin, a beneficial bioactive product specifically found in Cordyceps, has received attention in various bioindustrial applications such as in pharmaceuticals, functional...
Sat Sep 07, 2019 03:00
Biomolecules, Vol. 9, Pages 458: Chitosan Beads Incorporated with Essential Oil of Thymus capitatus: Stability Studies on Red Tilapia Fillets Biomolecules doi: 10.3390/biom9090458 Authors: Mayra Alejandra Valencia Junca Cesar Valencia Edwin Flórez López Johannes Delgado-Ospina Paula A. Zapata Moisés Solano Carlos David Grande Tovar Red Tilapia is one of the most consumed but perishable fish in the world. As a result, it requires preservation methods for safe consumption...
Sat Sep 07, 2019 03:00
Biomolecules, Vol. 9, Pages 459: Isolation and Quantification of Sphingosine and Sphinganine from Rat Serum Revealed Gender Differences Biomolecules doi: 10.3390/biom9090459 Authors: Graham Brogden Diab M. Husein Pablo Steinberg Hassan Y. Naim Sphingolipids are an important group of lipids that play crucial roles in living cells, facilitating cell recognition, signal transduction and endocytosis. The concentration of sphingosine and some of its derivatives like sphinganine may...
Sat Sep 07, 2019 03:00
Biomolecules, Vol. 9, Pages 457: Small, Smaller, Smallest: Minimal Structural Requirements for a Fully Functional Box C/D Modification Guide RNA Biomolecules doi: 10.3390/biom9090457 Authors: Svetlana Deryusheva Joseph G. Gall Site-specific 2’-O-ribose methylation is an abundant post-transcriptional modification mediated by small non-coding nuclear RNAs known as box C/D modification guide RNAs. The minimal structural requirements for these guide RNAs to function in higher...
Sat Sep 07, 2019 03:00
Biomolecules, Vol. 9, Pages 456: Comparison of PD-L1 Expression Status between Pure-Solid Versus Part-Solid Lung Adenocarcinomas Biomolecules doi: 10.3390/biom9090456 Authors: Kenichi Suda Masaki Shimoji Shigeki Shimizu Katsuaki Sato Masato Chiba Kenji Tomizawa Toshiki Takemoto Junichi Soh Tetsuya Mitsudomi Although lung adenocarcinomas (LADs) with ground-glass opacity (GGO; part-solid tumors) have been shown to differ from those without GGO (pure-solid tumors)...
Sat Sep 07, 2019 03:00
Biomolecules, Vol. 9, Pages 460: Inhibition of Rho GTPases in Invertebrate Growth Cones Induces a Switch in Responsiveness to Retinoic Acid Biomolecules doi: 10.3390/biom9090460 Authors: Alysha Johnson Tamara I. N. Nasser Gaynor E. Spencer During development, growth cones are essential for axon pathfinding by sensing numerous guidance cues in their environment. Retinoic acid, the metabolite of vitamin A, is important for neurite outgrowth during vertebrate development, but may...
Sat Sep 07, 2019 03:00
Biomolecules, Vol. 9, Pages 455: Heteroplasmic Variants of Mitochondrial DNA in Atherosclerotic Lesions of Human Aortic Intima Biomolecules doi: 10.3390/biom9090455 Authors: Sobenin Zhelankin Khasanova Sinyov Medvedeva Sagaidak Makeev Kolmychkova Smirnova Sukhorukov Postnov Grechko Orekhov Mitochondrial dysfunction and oxidative stress are likely involved in atherogenesis. Since the mitochondrial genome variation can alter functional activity...
Fri Sep 06, 2019 03:00
Biomolecules, Vol. 9, Pages 454: Discovery of the Liver Hyaluronan Receptor for Endocytosis (HARE) and Its Progressive Emergence as the Multi-Ligand Scavenger Receptor Stabilin-2 Biomolecules doi: 10.3390/biom9090454 Authors: Weigel Since the discovery of a novel liver hyaluronan (HA) clearance receptor in 1981 by Laurent, Fraser and coworkers, 22 different ligands cleared by the renamed receptor (the Hyaluronan Receptor for Endocytosis (HARE); Stabilin-2 (Stab2)) were discovered over...
Fri Sep 06, 2019 03:00
Brain Sciences, Vol. 9, Pages 227: Infant Understanding of Different Forms of Social Exclusion Brain Sciences doi: 10.3390/brainsci9090227 Authors: Claire Nicole Prendergast In a series of eye-tracking studies, we investigated preverbal infants’ understanding of social exclusion by analyzing their gaze behaviors as they were familiarized with animations depicting social acceptance and explicit or implicit social exclusion. In addition, we implemented preferential reaching and...
Sat Sep 07, 2019 03:00
Brain Sciences, Vol. 9, Pages 226: On Variation in Mindfulness Training: A Multimodal Study of Brief Open Monitoring Meditation on Error Monitoring Brain Sciences doi: 10.3390/brainsci9090226 Authors: Lin Eckerle Peng Moser A nascent line of research aimed at elucidating the neurocognitive mechanisms of mindfulness has consistently identified a relationship between mindfulness and error monitoring. However, the exact nature of this relationship is unclear, with studies reporting...
Fri Sep 06, 2019 03:00
Cancers, Vol. 11, Pages 1333: Radiation Tolerance in Tardigrades: Current Knowledge and Potential Applications in Medicine Cancers doi: 10.3390/cancers11091333 Authors: K. Ingemar Jönsson Tardigrades represent a phylum of very small aquatic animals in which many species have evolved adaptations to survive under extreme environmental conditions, such as desiccation and freezing. Studies on several species have documented that tardigrades also belong to the most radiation-tolerant animals...
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Cancers, Vol. 11, Pages 1330: Transport-Mediated Oxaliplatin Resistance Associated with Endogenous Overexpression of MRP2 in Caco-2 and PANC-1 Cells Cancers doi: 10.3390/cancers11091330 Authors: Riya Biswas Piyush Bugde Ji He Fabrice Merien Jun Lu Dong-Xu Liu Khine Myint Johnson Liu Mark McKeage Yan Li Our recent publications showed that multidrug resistance protein 2 (MRP2, encoded by the ABCC2 gene) conferred oxaliplatin resistance in human liver cancer HepG2...
Sun Sep 08, 2019 03:00
Cancers, Vol. 11, Pages 1331: Elimination of SOX2/OCT4-Associated Prostate Cancer Stem Cells Blocks Tumor Development and Enhances Therapeutic Response Cancers doi: 10.3390/cancers11091331 Authors: Prasanna Kumar Vaddi Mark A. Stamnes Huojun Cao Songhai Chen SOX2 and OCT4 are key regulators of embryonic stem cell pluripotency. They are overexpressed in prostate cancers and have been associated with cancer stem cell (CSC) properties. However, reliable tools for detecting and...
Sun Sep 08, 2019 03:00
Cancers, Vol. 11, Pages 1332: Bone Metastases in Neuroendocrine Neoplasms: From Pathogenesis to Clinical Management Cancers doi: 10.3390/cancers11091332 Authors: Barbara Altieri Carla Di Dato Chiara Martini Concetta Sciammarella Antonella Di Sarno Annamaria Colao Antongiulio Faggiano on behalf of NIKE Group on behalf of NIKE Group Bone represents a common site of metastases for several solid tumors. However, the ability of neuroendocrine neoplasms (NENs) to localize...
Sun Sep 08, 2019 03:00
Cancers, Vol. 11, Pages 1329: Morpho-Molecular Assessment Indicates New Prognostic Aspects and Personalized Therapeutic Options in Sinonasal Melanoma Cancers doi: 10.3390/cancers11091329 Authors: Sandra N. Freiberger Grégoire B. Morand Patrick Turko Ulrich Wager Reinhard Dummer Martin Hüllner David Holzmann Niels J. Rupp Mitchell P. Levesque Sinonasal melanoma is a rare subtype of melanoma and little is known about its molecular fingerprint. Systemic treatment...
Sat Sep 07, 2019 03:00
Cancers, Vol. 11, Pages 1327: Selective Inhibition of Histone Deacetylases 1/2/6 in Combination with Gemcitabine: A Promising Combination for Pancreatic Cancer Therapy Cancers doi: 10.3390/cancers11091327 Authors: Richard S. Laschanzky Lisa E. Humphrey Jihyun Ma Lynette M. Smith Thomas J. Enke Surendra K. Shukla Aneesha Dasgupta Pankaj K. Singh Gillian M. Howell Michael G. Brattain Quan P. Ly Adrian R. Black Jennifer D. Black Pancreatic ductal adenocarcinoma...
Sat Sep 07, 2019 03:00
Cancers, Vol. 11, Pages 1328: Anthracyclines Suppress Both NADPH Oxidase- Dependent and -Independent NETosis in Human Neutrophils Cancers doi: 10.3390/cancers11091328 Authors: Meraj A. Khan Adam D’Ovidio Harvard Tran Nades Palaniyar Neutrophil extracellular traps (NETs) are cytotoxic DNA-protein complexes that play positive and negative roles in combating infection, inflammation, organ damage, autoimmunity, sepsis and cancer. However, NETosis regulatory effects of most of the...
Sat Sep 07, 2019 03:00
Cancers, Vol. 11, Pages 1326: Survival Benefits of Chemotherapy for Patients with Advanced Pancreatic Cancer in A Clinical Real-World Cohort Cancers doi: 10.3390/cancers11091326 Authors: Maximilian Kordes Jingru Yu Oscar Malgerud Maria Gustafsson Liljefors J. -Matthias Löhr Clinical outcomes of chemotherapy for patients with advanced pancreatic adenocarcinoma in a real-world setting might differ from outcomes in randomized clinical trials (RCTs). Here we show in a single-institution...
Sat Sep 07, 2019 03:00
Cancers, Vol. 11, Pages 1325: Panoptic View of Prognostic Models for Personalized Breast Cancer Management Cancers doi: 10.3390/cancers11091325 Authors: Geetanjali Saini Karuna Mittal Padmashree Rida Emiel A. M. Janssen Keerthi Gogineni Ritu Aneja The efforts to personalize treatment for patients with breast cancer have led to a focus on the deeper characterization of genotypic and phenotypic heterogeneity among breast cancers. Traditional pathology utilizes microscopy...
Sat Sep 07, 2019 03:00
Cancers, Vol. 11, Pages 1323: Clinical Significance of ABCB1 in Acute Myeloid Leukemia: A Comprehensive Study Cancers doi: 10.3390/cancers11091323 Authors: Boyer Gonzales Barthélémy Marceau-Renaut Peyrouze Guihard Lepelley Plesa Nibourel Delattre Wetterwald Pottier Plantier Botton Dombret Berthon Preudhomme Roumier Cheok ABCB1 is a member of the ATP binding cassette transporter family and high ABCB1 activity is...
Fri Sep 06, 2019 03:00
Cancers, Vol. 11, Pages 1322: A Tunable Nanoplatform of Nanogold Functionalised with Angiogenin Peptides for Anti-Angiogenic Therapy of Brain Tumours Cancers doi: 10.3390/cancers11091322 Authors: Naletova Cucci D’Angeli Anfuso Magrì La Mendola Lupo Satriano Angiogenin (ANG), an endogenous protein that plays a key role in cell growth and survival, has been scrutinised here as promising nanomedicine tool for the modulation of pro-/anti-angiogenic processes...
Fri Sep 06, 2019 03:00
Cancers, Vol. 11, Pages 1320: Everything in Moderation: Lessons Learned by Exploiting Moderate Replication Stress in Cancer Cancers doi: 10.3390/cancers11091320 Authors: Nazareth Jones Gabrielli The poor selectivity of standard cytotoxic chemotherapy regimens causes severe side-effects in patients and reduces the quality of life during treatment. Targeting cancer-specific vulnerabilities can improve response rates, increase overall survival and limit toxic side effects in patients....
Fri Sep 06, 2019 03:00
Cancers, Vol. 11, Pages 1324: Radiotherapy-Induced Changes in the Systemic Immune and Inflammation Parameters of Head and Neck Cancer Patients Cancers doi: 10.3390/cancers11091324 Authors: Balázs Kis Badie Bogdándi Candéias Garcia Dominczyk Frey Gaipl Jurányi Kocsis Rutten Sáfrány Widlak Lumniczky Though radiotherapy is a local therapy, it has systemic effects mainly influencing immune and inflammation processes. This has important...
Fri Sep 06, 2019 03:00
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