Κυριακή 1 Σεπτεμβρίου 2019


Relationships between the clinical phenotypes and genetic variants associated with the immunological mechanism in childhood idiopathic nephrotic syndrome: protocol for a prospective observational single-centre cohort study.
Related ArticlesRelationships between the clinical phenotypes and genetic variants associated with the immunological mechanism in childhood idiopathic nephrotic syndrome: protocol for a prospective observational single-centre cohort study. BMJ Open. 2019 Aug 28;9(8):e028717 Authors: Chan H, Lee H, Yang X, Wang J, Yang X, Gan C, Xiao H, Li Q, Jiao J, Wu D, Zhang G, Wang M, Yang H, Li Q Abstract INTRODUCTION: Idiopathic nephrotic syndrome (INS) is the...
pubmed: "bmj open"[jour]
Sat Aug 31, 2019 14:27
The Uppsala-Stockholm Assisted Reproductive Techniques (UppStART) study.
Related ArticlesThe Uppsala-Stockholm Assisted Reproductive Techniques (UppStART) study. BMJ Open. 2019 Aug 28;9(8):e028866 Authors: Iliadou AN, Öberg AS, Pege J, Rodriguez-Wallberg KA, Olofsson JI, Holte J, Wramsby H, Wramsby M, Cnattingius S, Cesta CE Abstract PURPOSE: The Uppsala-Stockholm Assisted Reproductive Techniques (UppStART) study is a prospectively recruited sample of couples undergoing assisted reproduction in Stockholm and Uppsala county...
pubmed: "bmj open"[jour]
Sat Aug 31, 2019 14:27
Complex intervention in augmentative and alternative communication (AAC) care in Germany: a study protocol of an evaluation study with a controlled mixed-methods design.
Related ArticlesComplex intervention in augmentative and alternative communication (AAC) care in Germany: a study protocol of an evaluation study with a controlled mixed-methods design. BMJ Open. 2019 Aug 28;9(8):e029469 Authors: Zinkevich A, Uthoff SAK, Boenisch J, Sachse SK, Bernasconi T, Ansmann L Abstract INTRODUCTION: The current practice of service delivery in Germany for people with complex communication needs (CCN) who are in need of augmentative...
pubmed: "bmj open"[jour]
Sat Aug 31, 2019 14:27
Using electronic health record data to establish a chronic kidney disease surveillance system in China: protocol for the China Kidney Disease Network (CK-NET)-Yinzhou Study.
Related ArticlesUsing electronic health record data to establish a chronic kidney disease surveillance system in China: protocol for the China Kidney Disease Network (CK-NET)-Yinzhou Study. BMJ Open. 2019 Aug 28;9(8):e030102 Authors: Wang J, Bao B, Shen P, Kong G, Yang Y, Sun X, Ding G, Gao B, Yang C, Zhao M, Lin H, Zhang L Abstract INTRODUCTION: Chronic kidney disease (CKD) is an important public health problem worldwide. However, there are few active...
pubmed: "bmj open"[jour]
Sat Aug 31, 2019 14:27
Longitudinal study of use and cost of subacromial decompression surgery: the need for effective evaluation of surgical procedures to prevent overtreatment and wasted resources.
Related ArticlesLongitudinal study of use and cost of subacromial decompression surgery: the need for effective evaluation of surgical procedures to prevent overtreatment and wasted resources. BMJ Open. 2019 Aug 28;9(8):e030229 Authors: Jones T, Carr AJ, Beard D, Linton MJ, Rooshenas L, Donovan J, Hollingworth W Abstract OBJECTIVES: To illustrate the need for better evaluation of surgical procedures, we investigated the use and cost of subacromial decompression...
pubmed: "bmj open"[jour]
Sat Aug 31, 2019 14:27
Modern contraceptive use among sexually active women aged 15-19 years in North-Western Tanzania: results from the Adolescent 360 (A360) baseline survey.
Related ArticlesModern contraceptive use among sexually active women aged 15-19 years in North-Western Tanzania: results from the Adolescent 360 (A360) baseline survey. BMJ Open. 2019 Aug 28;9(8):e030485 Authors: Nsanya MK, Atchison CJ, Bottomley C, Doyle AM, Kapiga SH Abstract OBJECTIVES: To describe differences in modern contraceptive use among adolescent women aged 15-19 years according to their marital status and to determine factors associated with...
pubmed: "bmj open"[jour]
Sat Aug 31, 2019 14:27
Evaluation of policies for free maternal healthcare in low/middle-income countries: a scoping review protocol.
Related ArticlesEvaluation of policies for free maternal healthcare in low/middle-income countries: a scoping review protocol. BMJ Open. 2019 Aug 28;9(8):e031557 Authors: Seki RP, Hendrie D, Daire J Abstract INTRODUCTION: Improving maternal health remains a health priority at the global and national levels. As part of the global strategy, many low/middle-income countries (LMICs) have implemented free primary healthcare policies for different service...
pubmed: "bmj open"[jour]
Sat Aug 31, 2019 14:27
Semistructured interviews regarding patients' perceptions of Choosing Wisely and shared decision-making: an Australian study.
Related ArticlesSemistructured interviews regarding patients' perceptions of Choosing Wisely and shared decision-making: an Australian study. BMJ Open. 2019 Aug 28;9(8):e031831 Authors: Allen J, King R, Goergen SK, Melder A, Neeman N, Hadley A, Hutchinson AM Abstract OBJECTIVES: This study aimed to examine how patients perceive shared decision-making regarding CT scan referral and use of the five Choosing Wisely questions with their general practitioner...
pubmed: "bmj open"[jour]
Sat Aug 31, 2019 14:27
Correction: Strategies occupational therapists employ to facilitate work-related transitions for persons with hand injuries: a study protocol for a scoping review.
Related ArticlesCorrection: Strategies occupational therapists employ to facilitate work-related transitions for persons with hand injuries: a study protocol for a scoping review. BMJ Open. 2019 Aug 28;9(8):e027402corr1 Authors: PMID: 31467058 [PubMed - in process]
pubmed: "bmj open"[jour]
Sat Aug 31, 2019 14:27
"BMJ Open"[jour]; +17 new citations
17 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "BMJ Open"[jour] These pubmed results were generated on 2019/09/01PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: "bmj open"[jour]
Sun Sep 01, 2019 13:30
"BMJ Open"[jour]; +17 new citations
17 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "BMJ Open"[jour] These pubmed results were generated on 2019/09/01PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: "bmj open"[jour]
Sun Sep 01, 2019 15:25
medical science; +2683 new citations
2683 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/08/30PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Medical Science
Fri Aug 30, 2019 14:20
medical science; +2683 new citations
2683 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/08/30PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Medical Science
Fri Aug 30, 2019 16:20
medical science; +2596 new citations
2596 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/08/31PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Medical Science
Sat Aug 31, 2019 14:10
medical science; +2596 new citations
2596 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/08/31PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Medical Science
Sat Aug 31, 2019 16:09
medical science; +721 new citations
721 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/09/01PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Medical Science
Sun Sep 01, 2019 14:04
medical science; +721 new citations
721 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/09/01PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Medical Science
Sun Sep 01, 2019 16:02
הזמנה לערב עיון
במלאת עשרים שנה לפטירתו של פרופ' שלמה מורג ז"ל נקיים ערב עיון לזכרו ביום ראשון ט"ו באלול, 15 בספטמבר, בשעה 17:00 בבית האקדמיה מספר המקומות מוגבל – נשמח לראותכם. טופס לרישום מוקדם [contact-form-7] ניתן לאשר השתתפות גם בדוא"ל חוזר ivrit@hebrew-academy.org.il או בטלפון 02-6493555 The post הזמנה לערב עיון appeared first on האקדמיה ללשון העברית.
האקדמיה ללשון העברית
Sun Sep 01, 2019 12:04
קבקב וכפכף
המילה המקורית מן השתיים היא המילה קַבְקַב. מקורה במילה הערבית قَبْقَاب (קַבְּקַאבּ), המשמשת במשמעות נעל עץ, כנראה בשל קול הנקישות שמשמיעה נעל זו בעת ההליכה בה.[1] בעברית של ראשית המאה העשרים אימצו את המילה הערבית אגב סיגולה לעברית – בבי"תין רפות – באותה המשמעות: וראיתי את חמוקי שוקיה ואת רגליה העגולות בהתנענען על קבקבים של עץ. (הצבי, 28 במרץ 1912) פתאם נרתעה, כאִלו עמדו רגליה על עברי פי־פחת, נשמט קבקבהּ מעל רגלה והתגלגל בדפיקה על המדרגות. (יצחק שמי, אב ובנותיו, 1923) הוא [הרב המקובל והקדוש רחמים...
האקדמיה ללשון העברית
Sun Sep 01, 2019 14:18
הרצאה בליל המדענים
השנה אנחנו משתתפים לראשונה באירועי ליל המדענים, שבו פותחת האוניברסיטה העברית בירושלים את שעריה לקהל הרחב וחושפת לפניו את אוצרות הידע שלה. י"ט באלול, 19 בספטמבר, בשעה 22:00 חדר אובלי, בניין בית ברטר למדע (קמפוס גבעת רם, ירושלים) הרצאתה של רונית גדיש, המזכירה המדעית של האקדמיה ללשון העברית: "מתחיית העברית לעברית החיה – בין פעולות יחידים לפעילות ממסדית" תחיית העברית בארץ ישראל בסוף המאה ה־19 ותחילת המאה ה־20 אינה רק תוצאה של פעילות ממוסדת של ועד הלשון ושל המורים אלא גם פעולתם של יחידים. נספר את סיפוריהן...
האקדמיה ללשון העברית
Sun Sep 01, 2019 13:31
RSEQ Awards 2019 / RSEQ Binational Awards 2019 / And also in the News
Angewandte Chemie International Edition
Thu Aug 29, 2019 12:44
Interfacial Enhancement by r‐Al2O3 of Electrochemical Oxidative Dehydrogenation of Ethane to Ethylene in Solid Oxide Electrolysis Cells
Oxidative dehydrogenation of ethane (ODE) is limited by the facile deep oxidation and potential safety hazard. Herein, electrochemical ODE reaction is incorporated into the anode of a solid oxide electrolysis cell, utilizing the oxygen species generated at anode to catalytically convert ethane, which can avoid deep oxidation and reaction unsafety. By infiltrating g‐Al 2 O 3 onto the surface of La 0.6 Sr 0.4 Co 0.2 Fe 0.8 O 3‐ δ ‐Sm 0.2 Ce 0.8 O 2‐ δ (LSCF‐SDC) anode, the ethylene...
Angewandte Chemie International Edition
Thu Aug 29, 2019 17:40
Two birds with one stone: a polymer solution to prevent nanoclustering and improve the selectivity of metal nanoparticles for electrocatalytic CO2 reduction
The stability of metal nanocatalysts for electrocatalytic CO2 reduction is of key importance for any practical application. We report the use of two polymeric N‐heretocyclic carbenes (NHC) (polydentate and monodentate) to stabilize metal nanocatalysts (Au and Pd) for efficient CO2 electroreduction. Compared with other conventional ligands including thiols and amines, metal‐carbene bonds that are stable under reductive potentials prevent the nanoclustering of nanoparticles. In particular, Au nanocatalysts...
Angewandte Chemie International Edition
Thu Aug 29, 2019 17:41
Enantioselective Rhodium‐Catalyzed Addition of Arylboroxines to N‐Unprotected Ketimines: Efficient Synthesis of Cipargamin
Highly enantioselective rhodium‐catalyzed addition of arylboroxines to N‐unprotected ketimines are realized for the first time by employing chiral BIBOP‐type ligands with the Rh loading as low as 1 mol %. A range of chiral α‐trifluoromethyl‐α,α‐diaryl α‐tertiary amines or 3‐amino‐3‐aryloxindoles were formed in excellent ee’s and yields with the employment of WingPhos or PFBO‐BIBOP as the ligand. The method has enabled an efficient enantioselective synthesis of cipargamin.
Angewandte Chemie International Edition
Thu Aug 29, 2019 17:42
Combined Photoredox/Enzymatic C–H Benzylic Hydroxylations Rick C. Betoria, Catherine M. Maya, Karl A. Scheidt*a
Chemical transformations that install heteroatoms into C–H bonds are of significant interest because they streamline the construction of value‐added small molecules. Direct C−H oxyfunctionalization, or the one step conversion of a C–H bond to a C–O bond, could be a highly enabling transformation due to the prevalence of the resulting enantioenriched alcohols in pharmaceuticals and natural products,. Here we report a single‐flask photoredox/enzymatic process for direct C–H hydroxylation that proceeds...
Angewandte Chemie International Edition
Thu Aug 29, 2019 20:00
Generation and Applications of the Hydroxide Trihydrate Anion, [OH(OH2)3]−, Stabilized by a Weakly Coordinating Cation
The hydroxide trihydrate anion was generated for the first time and structurally characterized thanks to the use of a weakly coordinating phosphazenium counterion. As B. Hoge et al. describe in their Communication (DOI: https://doi.org/10.1002/anie.20190858910.1002/anie.201908589), the space‐filling phosphazenium cation represents an impregnable castle wall in protecting and stabilizing this rare anion. Under vacuum the salt decomposes like a fragile aqueous “hydroxide soap bubble”.
Angewandte Chemie International Edition
Thu Aug 29, 2019 20:04
Van der Waals Heterostructured MOF‐on‐MOF Thin Films: Cascading Functionality to Realize Advanced Chemiresistive Sensing
Heterostructured metal–organic framework (MOF)‐on‐MOF thin films combined with van‐der‐Waals forces offer functionality beyond that of a single MOF layer. In their Communication (DOI: https://doi.org/10.1002/anie.20190777210.1002/anie.201907772), G. Xu et al. present a device that combines molecular sieving and chemiresistive sensing MOF layers. The MOF‐on‐MOF thin film demonstrates the highest response to benzene among reported recoverable chemiresistive sensing materials active at room temperature....
Angewandte Chemie International Edition
Thu Aug 29, 2019 20:04
Direct Observation of Oxygen Vacancy Self‐Healing on TiO2 Photocatalysts for Solar Water Splitting
Oxygen vacancy (Vo) self‐healing on TiO2 photocatalysts in water splitting reaction has been studied by the combination of synchronous illumination X‐ray photoelectron spectroscopy with density functional theory calculation. Abstract Oxygen vacancy (Vo) on transition metal oxides plays a crucial role in determining their chemical/physical properties. Conversely, the capability to directly detect the changing process of oxygen vacancies (Vos) will be important to realize their full potentials...
Angewandte Chemie International Edition
Thu Aug 29, 2019 20:04
Phosphite‐Catalyzed C−H Allylation of Azaarenes via an Enantioselective [2,3]‐Aza‐Wittig Rearrangement
Powered by rearomatization: The adduct of a nucleophilic chiral phosphite with an azaarene N‐allyl salt undergoes a stereoselective base‐mediated aza‐Wittig rearrangement. This method efficiently generates tertiary and quaternary chiral centers in isoquinoline, quinoline, and pyridine systems along with an alkene handle for further functionalization. Abstract A phosphite‐mediated [2,3]‐aza‐Wittig rearrangement has been developed for the regio‐ and enantioselective allylic alkylation of six‐membered...
Angewandte Chemie International Edition
Thu Aug 29, 2019 20:04
Boosting Electrochemical Reduction of CO2 at a Low Overpotential by Amorphous Ag‐Bi‐S‐O Decorated Bi0 Nanocrystals
Low‐overpotential selective eCO2RR: A formate efficiency of 94.3 % at a low overpotential of 450 mV was achieved by an amorphous Ag‐Bi‐S‐O decorated Bi0 nanocatalyst derived from bimetal‐S‐O composite Ag0.95BiS0.75O3.1. The performance arises from the role of S in accelerating the dissociation of H2O and the higher local pH resulted from the existence of Ag. Abstract Bimetal‐S‐O composites have been rarely researched in electrochemical reduction of CO2. Now, an amorphous Ag‐Bi‐S‐O decorated...
Angewandte Chemie International Edition
Thu Aug 29, 2019 20:05
Titanium‐Mediated Synthesis of Spirocyclic NH‐Azetidines from Oxime Ethers
In exchange: The TiIV‐mediated synthesis of spirocyclic NH‐azetidines from oxime ethers and either an alkyl Grignard reagent or terminal olefin ligand exchange coupling partner is described. This transformation proceeds in moderate yield to furnish previously unreported and structurally diverse NH‐azetidines in a single step. Abstract The TiIV‐mediated synthesis of spirocyclic NH‐azetidines from oxime ethers using either an alkyl Grignard reagent or terminal olefin ligand exchange coupling...
Angewandte Chemie International Edition
Thu Aug 29, 2019 22:00
De Novo Designed Highly Efficient Photosensitizer as a Universal Scaffold for Activatable Photosensitizer with Completely Inhibited Photosensitivity
Activatable photosensitizers (aPSs) sensitive to specific stimuli hold enormous potential to effectively target multiple disease biomarkers and are therefore highly desirable for specific photodynamic therapy (PDT). Herein, we present a versatile design, based on the principle of hindering the initial photoexcitation step of the process of photosensitization, to access aPSs that are activated and fully recovered from completely inhibited state in the presence of specific biomarker. A de novo designed...
Angewandte Chemie International Edition
Fri Aug 30, 2019 12:10
Crystalline Cooperativity of Donor and Acceptor Segments in Double‐Cable Conjugated Polymers toward Efficient Single‐Component Organic Solar Cells
This work highlights that the crystalline cooperativity of donor and acceptor segment in double‐cable conjugated polymers plays an important role in the nanophase separation and photovoltaic performance in single‐component organic solar cells (SCOSCs). The work started from designing two double‐cable conjugated polymers with the same conjugated backbone and perylene bisimide (PBI) side units, in which PBIs were positioned symmetrically and perpendicularly (P1) and asymmetrically and slantingly (P2)...
Angewandte Chemie International Edition
Fri Aug 30, 2019 12:41
An Ultrastable Metal Azolate Framework with Binding Pockets for Optimal Carbon Dioxide Capture
In the evolution of metal−organic frameworks (MOFs) for carbon capture, a lasting challenge is to strike a balance between high uptake capacity/selectivity and low energy cost for regeneration. Meanwhile, these man‐made materials have to survive from practical demands such as stability under harsh conditions and feasibility of scale‐up synthesis. Reported here is a new MOF, Zn(imPim) (aka. MAF‐stu‐1), with an imidazole derivative ligand, featuring binding pockets that can accommodate CO 2 molecules...
Angewandte Chemie International Edition
Fri Aug 30, 2019 13:50
Sodium‐ and Potassium‐Hydrate Melts Containing Asymmetric Imide Anions for High‐Voltage Aqueous Batteries
For the first time, room‐temperature hydrate melts for Na and K systems were discovered by exploring optimized eutectic systems of Na and K salts with asymmetric imide anions, leading to a significant expansion of potential window, which will open new frontiers in aqueous electrolytes for high‐voltage and safe batteries. Abstract Aqueous Na‐ or K‐ion batteries could virtually eliminate the safety and cost concerns raised from Li‐ion batteries, but their widespread applications have generally...
Angewandte Chemie International Edition
Fri Aug 30, 2019 13:59
A Dual Killing Strategy: Photocatalytic Generation of Singlet Oxygen with Concomitant PtIV Prodrug Activation
Two paths to cell death: A ruthenium‐based mitochondrial‐targeting photosensitiser that enables the rapid catalytic conversion of PtIV prodrugs into their active PtII counterparts and drives the generation of singlet oxygen was designed. This duality drives two orthogonal cancer‐cell killing mechanisms with temporal and spatial control. Abstract A ruthenium‐based mitochondrial‐targeting photosensitiser that undergoes efficient cell uptake, enables the rapid catalytic conversion of PtIV prodrugs...
Angewandte Chemie International Edition
Fri Aug 30, 2019 14:09
2D Titania–Carbon Superlattices Vertically Encapsulated in 3D Hollow Carbon Nanospheres Embedded with 0D TiO2 Quantum Dots for Exceptional Sodium‐Ion Storage
Well‐ordered 2D superlattices of monolayer titania and carbon vertically encapsulated in hollow carbon nanospheres are embedded with TiO2 quantum dots, forming a 0D‐2D‐3D multi‐dimensional architecture. Benefiting from the intriguing merits of 2D superlattices and the synergistic effects of each building blocks, the multi‐dimensional architecture shows highly efficient Na+ storage performance. Abstract Two‐dimensional (2D) superlattices offer promising technological opportunities in tuning...
Angewandte Chemie International Edition
Fri Aug 30, 2019 14:09
Antiadhesive Nanosomes Facilitate Targeting of the Lysosomal GlcNAc Salvage Pathway through Derailed Cancer Endocytosis
Target practice: Antiadhesive nanosomes displaying covalent glycosidase inhibitors showed that the lysosomal exo‐glycohydrolases responsible for the GlcNAc salvage pathway in cancer cells are promising targets for the development of anticancer therapeutic nanomedicine. In this approach apoptotic cell death is induced through lysosomal membrane permeabilization. Abstract Activated endocytosis of extracellular macromolecules and their intracellular trafficking to lysosomes is an essential metabolic...
Angewandte Chemie International Edition
Fri Aug 30, 2019 14:11
Tetravinylallene
Allene spell is vinyl‐ly over! Syntheses of the fundamental hydrocarbon tetravinylallene (TVA) and substituted analogs are reported for the first time. The unprecedented power of TVAs in rapid complexity‐building chemistry is demonstrated, with controlled pericyclic sequences granting access to diverse multi‐cyclic structures in short order. Abstract The first chemical synthesis of tetravinylallene (3,5‐divinylhepta‐1,3,4,6‐tetraene) is reported. The final, key step of the synthesis involves...
Angewandte Chemie International Edition
Fri Aug 30, 2019 14:11

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