Evaluation of virtual surgical planning systems and customized devices in fibula free flap mandibular reconstructionAbstract Purpose The purpose of this study was to evaluate the accuracy of virtual planning using customized surgical devices (VP3D) in fibula free flap mandibular reconstruction. Methods Fourteen patients received VP3D and 16 patients underwent conventional surgery (CS). Virtual planning was compared to- Reducing Artifacts in Intracochlear Pressure Measurements to Study Sound Transmission by Bone Conduction Stimulation in HumansHypothesis: Intracochlear pressure (ICP) measurements during bone conduction (BC) stimulation may be affected by motion of the pressure sensor relative to the cochlear promontory bone, demonstrating the need to cement the sensor firmly to the cochlear bone. Background: ICP is a promising measurement tool for investigating the cochlear drive in BC transmission, but its use is not yet standardized. Previous ICP studies have reported artific
- Early Magnetic Resonance Imaging for Patients With Idiopathic Sudden Sensorineural Hearing Loss in an Emergency SettingObjective: The role of magnetic resonance (MR) imaging in idiopathic sudden sensorineural hearing loss (ISSHL) is controversial due to the inhomogeneity of clinical and MR protocols. The aim of this work is to relate early MR findings obtained immediately after the admission, with the clinical presentation, the audiological findings, and the outcomes of treatment. Study Design: Prospective observational study. Setting: Tertiary refer
- Long-term Implant Usage and Quality-of-Life in Sequential Bilateral Pediatric Cochlear ImplantationObjectives: Our primary objective was to investigate the long-term usage of cochlear implants (CIs) in children who underwent sequential bilateral CI (SeqBCI), and to study factors that impact usage. Our secondary objective was to understand the difference in subjective benefit and educational/employment status, between users and non-users of the second CI (CI2). Study Design: Prospective case series. Setting: Tertiary academic cente
- High Dose of Intratympanic Steroids for Sudden Sensorineural Hearing Loss SalvageObjective: Intratympanic (IT) steroid administration for sudden sensorineural hearing loss is offered as salvage to patients who failed systemic steroid treatment. Our objective was to study the audiometric and clinical outcomes of patients given salvage therapy with high-dose IT steroids instilled via ventilation tube. Study Design: Retrospective case review. Setting: Academic secondary medical center. Patients: One hundred thr
- Assessment of Health Care Utilization for Dizziness in Ambulatory Care Settings in the United StatesObjective: Describe patient and physician characteristics, and physician recommendations for ambulatory care visits for dizziness in the US. Study Design: Cross-sectional analysis of visits for dizziness from the National Ambulatory Medical Care Survey (2013–2015). Setting: Ambulatory care clinics in the US. Patients: 20.6 million weighted adult visits [mean age 58.7 (1.0)] for dizziness, identified using ICD-9-CM codes (386.00–
- An Exploratory Study on the Use of Event-Related Potentials as an Objective Measure of Auditory Processing and Therapy Effect in Patients With Tinnitus: A Transcranial Direct Current Stimulation StudyObjective: Treatment effect in tinnitus research is commonly evaluated by use of self-report questionnaires. As this is a solely subjective assessment method, the need for an objective measurement is paramount to genuinely evaluate the effects of therapeutic interventions. The current study explores the value of event-related potentials (ERPs) in the evaluation of high-definition transcranial direct current stimulation (HD-tDCS) for tinnitus t
- Glucocorticoid for Hearing Preservation After Cochlear Implantation: A Systemic Review and Meta-analysis of Animal StudiesObjectives: To conduct systematic review and meta-analyses of preclinical studies describing the efficacy of glucocorticoids administered via different routes for hearing preservation after cochlear implantation. Data Sources: A literature search was performed in PubMed to identify peer-reviewed articles published before December 31, 2017, with no language restrictions. Search components were “Cochlear implant,” “Glucocorticoids,” and “He
- Neuropathological Findings of Dementia Associated With Subjective Hearing LossObjective: The relationship between hearing loss and cognitive decline is of great importance with growing evidence of hearing loss as an independent modifiable risk factor for dementia. Our goal was to evaluate for differences in dementia neuropathology between subjective normal hearing and hearing loss subjects, as well as subjects who wore hearing aids. Study Design: Retrospective database. Setting: Tertiary academic center. Pat
- Cognitive Performance in Chronic Tinnitus Patients: A Cross-Sectional Study Using the RBANS-HObjective: Many tinnitus patients report cognitive deficits such as concentration and attention difficulties. The aim of this study was to comprehensively assess cognitive functioning in tinnitus patients using a standardized test battery, the repeatable battery for the assessment of neuropsychological status adjusted for hearing impaired individuals (RBANS-H). Study Design: Cross-sectional study. Setting: Tertiary referral center.
- Intraoperative Monitoring of Auditory Function During Lateral Skull Base SurgeryObjective: We present a unique case of a patient with a jugular foramen tumor with serviceable hearing. This study discusses the audiometric results and intraoperative electrocochleographic (ECochG) findings recorded during tumor removal to illustrate the potential utility of this technique in skull base surgery. Patients: A 22-year-old female patient presented with a jugular foramen schwannoma and associated symptoms of right-sided otalg
- Outcomes and Predictive Factors of Electroacoustic Stimulation Rehabilitation in Children With Limited Low-Frequency HearingObjective: To evaluate the clinical feasibility and auditory benefits of hearing rehabilitation using electroacoustic stimulation (EAS) after cochlear implantation (CI) and to identify the predictive factors for successful EAS rehabilitation in children with limited low-frequency hearing. Study Design: Retrospective case review. Setting: Tertiary referral hospital. Patients: Seventeen children (21 ears) under the age of 15 years
- YESTERDAY
- Reducing Artifacts in Intracochlear Pressure Measurements to Study Sound Transmission by Bone Conduction Stimulation in HumansHypothesis: Intracochlear pressure (ICP) measurements during bone conduction (BC) stimulation may be affected by motion of the pressure sensor relative to the cochlear promontory bone, demonstrating the need to cement the sensor firmly to the cochlear bone. Background: ICP is a promising measurement tool for investigating the cochlear drive in BC transmission, but its use is not yet standardized. Previous ICP studies have reported artific
- Early Magnetic Resonance Imaging for Patients With Idiopathic Sudden Sensorineural Hearing Loss in an Emergency SettingObjective: The role of magnetic resonance (MR) imaging in idiopathic sudden sensorineural hearing loss (ISSHL) is controversial due to the inhomogeneity of clinical and MR protocols. The aim of this work is to relate early MR findings obtained immediately after the admission, with the clinical presentation, the audiological findings, and the outcomes of treatment. Study Design: Prospective observational study. Setting: Tertiary refer
- Long-term Implant Usage and Quality-of-Life in Sequential Bilateral Pediatric Cochlear ImplantationObjectives: Our primary objective was to investigate the long-term usage of cochlear implants (CIs) in children who underwent sequential bilateral CI (SeqBCI), and to study factors that impact usage. Our secondary objective was to understand the difference in subjective benefit and educational/employment status, between users and non-users of the second CI (CI2). Study Design: Prospective case series. Setting: Tertiary academic cente
- High Dose of Intratympanic Steroids for Sudden Sensorineural Hearing Loss SalvageObjective: Intratympanic (IT) steroid administration for sudden sensorineural hearing loss is offered as salvage to patients who failed systemic steroid treatment. Our objective was to study the audiometric and clinical outcomes of patients given salvage therapy with high-dose IT steroids instilled via ventilation tube. Study Design: Retrospective case review. Setting: Academic secondary medical center. Patients: One hundred thr
- Assessment of Health Care Utilization for Dizziness in Ambulatory Care Settings in the United StatesObjective: Describe patient and physician characteristics, and physician recommendations for ambulatory care visits for dizziness in the US. Study Design: Cross-sectional analysis of visits for dizziness from the National Ambulatory Medical Care Survey (2013–2015). Setting: Ambulatory care clinics in the US. Patients: 20.6 million weighted adult visits [mean age 58.7 (1.0)] for dizziness, identified using ICD-9-CM codes (386.00–
- An Exploratory Study on the Use of Event-Related Potentials as an Objective Measure of Auditory Processing and Therapy Effect in Patients With Tinnitus: A Transcranial Direct Current Stimulation StudyObjective: Treatment effect in tinnitus research is commonly evaluated by use of self-report questionnaires. As this is a solely subjective assessment method, the need for an objective measurement is paramount to genuinely evaluate the effects of therapeutic interventions. The current study explores the value of event-related potentials (ERPs) in the evaluation of high-definition transcranial direct current stimulation (HD-tDCS) for tinnitus t
- Glucocorticoid for Hearing Preservation After Cochlear Implantation: A Systemic Review and Meta-analysis of Animal StudiesObjectives: To conduct systematic review and meta-analyses of preclinical studies describing the efficacy of glucocorticoids administered via different routes for hearing preservation after cochlear implantation. Data Sources: A literature search was performed in PubMed to identify peer-reviewed articles published before December 31, 2017, with no language restrictions. Search components were “Cochlear implant,” “Glucocorticoids,” and “He
- Neuropathological Findings of Dementia Associated With Subjective Hearing LossObjective: The relationship between hearing loss and cognitive decline is of great importance with growing evidence of hearing loss as an independent modifiable risk factor for dementia. Our goal was to evaluate for differences in dementia neuropathology between subjective normal hearing and hearing loss subjects, as well as subjects who wore hearing aids. Study Design: Retrospective database. Setting: Tertiary academic center. Pat
- Cognitive Performance in Chronic Tinnitus Patients: A Cross-Sectional Study Using the RBANS-HObjective: Many tinnitus patients report cognitive deficits such as concentration and attention difficulties. The aim of this study was to comprehensively assess cognitive functioning in tinnitus patients using a standardized test battery, the repeatable battery for the assessment of neuropsychological status adjusted for hearing impaired individuals (RBANS-H). Study Design: Cross-sectional study. Setting: Tertiary referral center.
- Intraoperative Monitoring of Auditory Function During Lateral Skull Base SurgeryObjective: We present a unique case of a patient with a jugular foramen tumor with serviceable hearing. This study discusses the audiometric results and intraoperative electrocochleographic (ECochG) findings recorded during tumor removal to illustrate the potential utility of this technique in skull base surgery. Patients: A 22-year-old female patient presented with a jugular foramen schwannoma and associated symptoms of right-sided otalg
- Outcomes and Predictive Factors of Electroacoustic Stimulation Rehabilitation in Children With Limited Low-Frequency HearingObjective: To evaluate the clinical feasibility and auditory benefits of hearing rehabilitation using electroacoustic stimulation (EAS) after cochlear implantation (CI) and to identify the predictive factors for successful EAS rehabilitation in children with limited low-frequency hearing. Study Design: Retrospective case review. Setting: Tertiary referral hospital. Patients: Seventeen children (21 ears) under the age of 15 years
- A bibliometric analysis of scientific production in the field of lingual orthodonticsDue to the lack of bibliometric studies in the field of lingual orthodontics in dentistry, the aim of this study was to assess the evolution and current status of activity in this field during the period 1978–...
- Prevalence of presbycusis in an otologically normal populationPublication date: Available online 7 September 2019Source: Acta Otorrinolaringológica EspañolaAuthor(s): Antonio Rodríguez-Valiente, Óscar Álvarez-Montero, Carmen Górriz-Gil, José Ramón García-BerrocalAbstractObjectivePresbycusis or age-related hearing loss is a bilaterally symmetric sensorineural hearing loss associated exclusively with age, excluding any other causes of hearing loss. Presbycusis is very relevant because of its high prevalence,
- The Role of Topical Probiotics on Skin Conditions: A Systematic Review of Animal and Human Studies and Implications for Future TherapiesAbstract There is increasing evidence that the intestinal microbiome plays an important role in modulating systemic inflammation and disease. Oral probiotics can modulate the intestinal microbiome and have demonstrated to be efficacious in treating topical skin conditions, such as atopic dermatitis, acne and rosacea. By proxy, exogenous application to the skin of probiotics should also promote a positive bacterial balance to mitigate or potent
- The relationship of arginophilic proteins of the nuclear organized regions and atopic dermatitis in childrenAbstract Backround The arginophilic proteins of nuclear organized regions (AgNOR), visualised with colloidal silver methods as black dots are known as AgNOR. To date, the relationship between AgNOR and cancer and inflammatory conditions has been investigated. However, there has been no report investigating the relationship between AgNOR and atopic dermatitis. The aim of this study was to investigate the relationship between atopic dermatitis
- Three-year prospective study on olfaction of patients with Parkinson’s diseasePublication date: Available online 8 September 2019Source: Auris Nasus LarynxAuthor(s): Hisami Fujio, Go Inokuchi, Shunsuke Kuroki, Shun Tatehara, Sayaka Katsunuma, Hisamoto Kowa, Ken-ichi NibuAbstractObjectiveWe conducted a 3-year prospective study on olfaction of patients with Parkinson’s disease (PD) in order to examine the severity and frequency of smell disorder in PD using odor identification test, Open Essence (OE) and to verify the
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- The association between video-nystagmography and sensory organization test of computerized dynamic posturography in patients with vestibular symptomsAbstract Objective Vertigo is a complex symptom which imposes diagnostic and treatment challenges. Laboratory evaluation of vertigo includes video-nystagmography (VNG) and computerized dynamic posturography (CDP) for the evaluation of different aspects of this complaint. There are vague indications for each test and potential disagreements between them. The aim of this study is to exam
- The effect of age on ossiculoplasty results: A retrospective evaluation of 60 casesPublication date: Available online 7 September 2019Source: Auris Nasus LarynxAuthor(s): Kadir Özdamar, Alper ŞenAbstractObjectiveThere are only a few studies evaluating ossiculoplasty results in the pediatric age group. Although the effect of different factors on the results of ossiculoplasty is investigated, the effect of age on ossiculoplasty results is not known. In this study, the effect of age on ossiculoplasty results has been in
- Intermediate-grade carcinoma of the parotid and the impact of adjuvant radiationPublication date: Available online 6 September 2019Source: American Journal of OtolaryngologyAuthor(s): Lauren North, Michael Stadler, Becky Massey, Bruce Campbell, Monica Shukla, Musaddiq Awan, Christopher J. Schultz, Aditya Shreenivas, Stuart Wong, Evan Graboyes, Patrick Pipkorn, Joseph ZengaAbstractPurposeTo determine the influence of adjuvant radiotherapy on survival in surgically-managed early stage intermediate-grade mucoepidermoid and aci
- Topical biomaterials to prevent post-tonsillectomy hemorrhageDespite advances in surgical technique, postoperative hemorrhage remains a common cause of mortality and morbidity for patients following tonsillectomy. Application of biomaterials at the time of tonsillectomy...
- Ataxia Telangiectasia MRIMRI brain shows:1. Moderate grade diffuse cerebellar atrophy. No associated Brainstem or cerebral cortical atrophy.2. Multiple punctate low signal intensity foci on GRE in bilateral cerebral white matter.Imaging diagnosis: Ataxia-telangiectasia.Ataxia Telangiectasia A rare multisystem condition with autosomal recessive inheritance, incidence at around 1:40,000-300,000 live births, sometimes classified as a phakomatosis.Characterized by mult
- Flat-based fitting: the evaluation and usefulness of a new strategy-based fitting approach for cochlear implants.Related ArticlesFlat-based fitting: the evaluation and usefulness of a new strategy-based fitting approach for cochlear implants. Eur Arch Otorhinolaryngol. 2019 Sep 05;: Authors: Kurz A, Hagen R, van de Heyning P, Mertens G Abstract PURPOSE: The traditional fitting method for cochlear implants (CI), the single-channel fitting (SCF), is effective but time-consuming. A fitting method that is significa
- Comparison of intubation and tracheotomy in adult patients with acute epiglottitis or supraglottitis.Related ArticlesComparison of intubation and tracheotomy in adult patients with acute epiglottitis or supraglottitis. Eur Arch Otorhinolaryngol. 2019 Sep 05;: Authors: Tapiovaara LK, Aro KLS, Bäck LJJ, Koskinen AIM Abstract PURPOSE: In acute epiglottitis (AE) or acute supraglottitis (AS), the management of the airway is crucial. We hypothesized that tracheotomized patients recover faster than intubat
- Cysts in gyrus rectus of frontal lobeClinical Details : 42 yo female, sometime in May 2019 suffered from an episode of un responsivity associated with no features to suggest a seizure. There was no excessive perspiration. She however regains consciousness spontaneously after about 15 minutes. Thereafter she was well but on the 9th of August abruptly lost consciousness, had abnormal tonic posturing of the limbs, hyper salivation but no tongue bite or incontinence. SHe however
- Injection laryngoplasty in infants with unilateral vocal cord paralysis: a survey of ASPO membersPublication date: Available online 6 September 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Minyoung Jang, Stacie Gregory, Jad Jabbour, Thomas C. Robey, Cecile Sulman, Robert ChunAbstractIntroductionUnilateral vocal cord paralysis (UVCP) in infants may be managed medically or surgically, with the latter including injection laryngoplasty (IL). However, there is limited information.regarding injection laryngoplasty
- Factors associated with employment discontinuation among older and working age survivors of oropharyngeal cancerAbstract Background Oropharyngeal cancer survivors experience difficulty returning to work after treatment. To better understand specific barriers to returning to work, we investigated factors associated with discontinuing employment among older and working‐age survivors. Methods The sample included 675 oropharyngeal cancer survivors (median: 6 years posttreatment) diagnosed from 2000 to 2013 and employed at diagnosis. Relative risk mod
- Office-based vs. operating room-performed laryngopharyngeal surgery: a review of cost differences.Related ArticlesOffice-based vs. operating room-performed laryngopharyngeal surgery: a review of cost differences. Eur Arch Otorhinolaryngol. 2019 Sep 05;: Authors: Schimberg AS, Wellenstein DJ, van den Broek EM, Honings J, van den Hoogen FJA, Marres HAM, Takes RP, van den Broek GB Abstract PURPOSE: Office-based transnasal flexible endoscopic surgery under topical anesthesia has recently been develop
- Orientation of the premaxilla in the origin of septal deviation.Related ArticlesOrientation of the premaxilla in the origin of septal deviation. Eur Arch Otorhinolaryngol. 2019 Sep 05;: Authors: Hyman AJ, Fastenberg JH, Stupak HD Abstract INTRODUCTION: While most people believe the nasal septum to have intrinsic deviation and overgrowth in patients seeking rhinoplasty, an alternative concept is that a mal-oriented premaxilla causes extrinsic septal buckling and e
- The significance of vascular loops in the internal auditory meatus: a true incidental imaging finding?Related ArticlesThe significance of vascular loops in the internal auditory meatus: a true incidental imaging finding? Eur Arch Otorhinolaryngol. 2019 Sep 05;: Authors: Li L, Amiraraghi N, Begbie F, Kontorinis G Abstract PURPOSE: To determine the clinical significance of vascular loops (VL) in the internal auditory meatus (IAM) and cerebellopontine angle (CPA). METHODS: We carried out a retr
- Three-dimensional imaging of vocalizing larynx by ultra-high-resolution computed tomography.Related ArticlesThree-dimensional imaging of vocalizing larynx by ultra-high-resolution computed tomography. Eur Arch Otorhinolaryngol. 2019 Sep 04;: Authors: Miyamoto M, Ohara A, Arai T, Koyanagi M, Watanabe I, Nakagawa H, Yokoyama K, Saito K Abstract PURPOSE: Ultra-high-resolution computed tomography (UHRCT) is an emerging imaging technology that is able to achieve simultaneous 160 slices with supe
- Congenital nasal pyriform aperture stenosis: Diagnosis, management and technical considerationsPublication date: Available online 5 September 2019Source: Acta Otorrinolaringológica EspañolaAuthor(s): Gilberto E. Marrugo Pardo, Juan S. Parra Charris, Andrés E. Parra Charris, Daniel F. Villa ZuluagaAbstractBackgroundCongenital nasal pyriform aperture stenosis (CNPAS) is a rare cause of nasal obstruction in neonates with respiratory distress manifestations. Diagnosis is made with craniofacial computed tomography, prompt and precise treatment
- First Report of Bilateral External Auditory Canal Cochlin Aggregates (“Cochlinomas”) with Multifocal Amyloid-Like Deposits, Associated with Sensorineural Hearing Loss and a Novel Genetic Variant in COCH Encoding CochlinAbstract Pathogenic variants in COCH, encoding cochlin, cause DFNA9 deafness disorder with characteristic histopathologic findings of cochlin deposits in the inner and middle ears. Here, we present the first case of deafness associated with bilateral external auditory canal (EAC) cochlin deposits, previously unreported evidence suggestive of cochlin-derived amyloid formation, and a novel COCH variant. A 54-year-old woman presen
- Development and Evaluation of an Autonomous Camera Control Algorithm on the da Vinci Surgical SystemAbstract Manual control of the camera arm in telerobotic surgical systems requires the surgeon to repeatedly interrupt the flow of the surgery. During surgery, there are instances when one or even both tools can drift out of the field of view. These issues may lead to increased workload and potential errors. We have performed a 20‐participant subject study (including four surgeons) to compare camera control with (a) an autonomous camera algorith
- Community health workers obtain similar results using cell-phone based hearing screening tools compared to otolaryngologists in low resourced settingsPublication date: Available online 5 September 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Justin R. Shinn, M. Geraldine Zuniga, Ian Macharia, Jim Reppart, James L. Netterville, Asitha D.L. JayawardenaAbstractObjectiveTo establish community health workers as reliable hearing screening operators in a technology-based pre-surgical hearing screening program in a low and middle-income country (LMIC).MethodsThis is a
- Dental Hygienists and Dentists as Providers of Oral Mucosa Screening and Brush BiopsiesCondition: Oral CancerIntervention: Diagnostic Test: Brush biopsySponsor: Dalarna County Council, SwedenNot yet recruiting
- Regional Block for Postoperative Free Flap CareCondition: Pain ManagementIntervention: Drug: ropivicaine 0.2%Sponsor: University of Alabama at BirminghamNot yet recruiting
- Study of Safety and Tolerability of Nivolumab Treatment Alone or in Combination With Relatlimab or Ipilimumab in Head and Neck CancerCondition: Head and Neck Squamous Cell Carcinoma (HNSCC)Interventions: Drug: Nivolumab; Drug: Relatlimab; Drug: IpilimumabSponsors: Robert Ferris; Bristol-Myers SquibbNot yet recruiting
- Intra and Extra Oral Inspection of Oral MucosaConditions: Oral Lichen Planus; Oral Leukoplakia; ErythroplakiaIntervention: Other: questionnaire surveySponsor: Dalarna County Council, SwedenNot yet recruiting
- SCIB1 in Melanoma Patients Receiving Pembrolizumab SCIB1-002Condition: Malignant MelanomaInterventions: Biological: SCIB1 administered with a small, hand-held electroporation device (TDS-IM v2.0).; Device: Electroporation device (TDS-IM v 2.0).Sponsor: Scancell LtdRecruiting
- A Study to Evaluate ENERGI-F703 GEL in Venous Leg UlcerCondition: Venous Leg UlcerInterventions: Drug: ENERGI-F703 GEL; Drug: ENERGI-F703 GEL matched vehicleSponsor: Energenesis Biomedical Co., Ltd.Not yet recruiting
- Compensation of Dynamic Electromagnetic Field Distortion Using Simultaneous Localization and Mapping Method with Application in Endobronchial Ultrasound‐Transbronchial Needle Aspiration (EBUS‐TBNA) GuidanceAbstract Background Electromagnetic (EM) based navigation methods without line‐of‐sight restrictions may improve lymph node sampling precision in Transbronchial needle aspiration (TBNA) procedure. However, EM tracking susceptibility to metallic objects severely declines its precision. Method We proposed to track the location of a tool in a dynamic bronchial phantom and compensate field distortion in a real‐time procedure. Extended Kalma
- Surgical outcomes and unique histological features of tonsils after tonsillectomy in adults with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndromePublication date: Available online 5 September 2019Source: Auris Nasus LarynxAuthor(s): Kohei Yamahara, Kana Lee, Yuki Egawa, Noriyuki Nakashima, Satoshi IkegamiAbstractObjectivesData on the adult-onset periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome are scarce. European studies reported that unlike pediatric-onset PFAPA, tonsillectomy is ineffective for adult-onset PFAPA. The aims of this study were (1)
- Feasibility of early activation after cochlear implantationAbstract Objectives The purpose of the study is to investigate feasibility of early activation after cochlear implantation by evaluating long term impedance change and speech perception. Methods We designed a case‐control study including 40 patients who underwent cochlear implantation surgeries. Between July 2015 and December 2016, we prospectively enrolled 20 subjects for early activation (within 24 hours after cochlear implantation).
- Sequence-based prediction of olfactory receptor responsesAbstractComputational prediction of how strongly an olfactory receptor responds to various odors can help in bridging the widening gap between the large number of receptors that have been sequenced and the small number of experiments measuring their responses. Previous efforts in this area have predicted the responses of a receptor to some odors, using the known responses of the same receptor to other odors. Here we present a method to predict th
- Multifocal perineural invasion is a better prognosticator than depth of invasion in oral squamous cell carcinomaAbstract Objectives Prognostic significance of perineural invasion (PNI) in oral squamous cell carcinoma (OSCC) characterized as unifocal and multifocal was compared to depth of invasion (DOI) and extranodal extension (ENE). Materials and Methods Univariable and multivariable analyses of 861 consecutive patients with OSCC undergoing treatment between 1995 and 2018 were performed, with local failure (LF) and disease‐specific mortality (D
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