Evolutionary theory suggests that phenotypic stasis is explained by natural selection or by constraints imposed by mutation and recombination of standing genetic variation. We performed experimental evolution from standing genetic variation with the nematode Caenorhabditis elegans, measuring locomotion behavior in outcrossing populations for 240 generations. We find that in our constant environment locomotion shows no directional divergence, due to both stabilizing and disruptive selection on specific...
Mon Sep 23, 2019 03:00
In many animals, mate choice is important for the maintenance of reproductive isolation between species. Traits important for mate choice and behavioural isolation are predicted to be under strong stabilising selection within species, however such traits can also exhibit variation at the population level driven by neutral and adaptive evolutionary processes. Here, we describe patterns of divergence among androconial and genital chemical profiles at inter- and intra-specific levels in mimetic Heliconius...
Mon Sep 23, 2019 03:00
The elemental composition of organisms relates to a suite of functional traits that change during development in response to environmental conditions. It may be a part of a phenomenon known as developmental programming, which hypothetically creates phenotypes that are better adapted to their environments. However, associations between developmental speed and elemental body composition are not well understood. We compared body mass, elemental body composition, food uptake and fat metabolism of Drosophila...
Mon Sep 23, 2019 03:00
Technology in Cancer Research &Treatment, Volume 18, Issue , January 2019. Objective:Unmethylated cytosine-phosphorothioate-guanine oligodeoxynucleotide, a synthetic oligodeoxynucleotide, has been used as an adjuvant in clinic and in the antitumor activity. However, the antitumor mechanism of cytosine-phosphorothioate-guanine oligodeoxynucleotide against human bladder cancer is unknown. The purpose of this study is to evaluate the cytotoxicity and molecular mechanism of anticancer effect of cytosine-phosphorothioate-guanine...
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