Esraa El-Kholy, Lobna KhaledIndian Journal of Nuclear Medicine 2019 34(4):271-277 Purpose: The aim of this study was to evaluate the accuracy of dual-time point in differentiating benign from malignant local recurrent lesions in pancreatic cancer. Patients and Methods: Thirty-four patients with pancreatic cancer (22 males and 12 females, mean age: 58.3 ± 10.3) who presented with soft-tissue lesions at the operative bed. Early whole-body positron emission tomography/computed tomography (PET/CT)...
Mon Sep 23, 2019 00:00
Nitin Gupta, Ritu Verma, Ethel Shangne BelhoIndian Journal of Nuclear Medicine 2019 34(4):349-350 Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare clinical entity involving musculoskeletal and dermatologic systems. Its main features are prominent inflammatory cutaneous and articular manifestations. Anterior chest wall pain, more commonly at sternoclavicular and sternocostal joints, along with palmoplantar pustulosis and acne can point to this uncommon syndrome....
Mon Sep 23, 2019 00:00
Abbas Yousefi-Koma, Yaser Shiravand, Mohsen QutbiIndian Journal of Nuclear Medicine 2019 34(4):326-328 A 65-year-old patient with acute lymphoblastic leukemia presented for an 18fluoro-2-deoxy-d-glucose positron emission tomography computed tomography (18FDG PET) after several courses of chemotherapy for metastatic evaluation. Unexpectedly, on 18FDG PET scan, no discernible uptake was observed in the visceral organs, but instead, the skeleton/bone marrow showed homogenously intense metabolic...
Mon Sep 23, 2019 00:00
Journal of Adolescent and Young Adult Oncology, Ahead of Print.
Mon Sep 23, 2019 10:00
Journal of Adolescent and Young Adult Oncology, Ahead of Print.
Mon Sep 23, 2019 10:00
Abstract Purpose To describe the procedures and investigate the hearing outcomes and complications after revision surgery for patients with otosclerosis in Sweden and compare these with previously published reports and to investigate factors that may predict the outcomes of revision surgery. Methods A total of 254 patients from the Swedish Quality...
Mon Sep 23, 2019 03:00
Abstract Purpose Warthin tumour (WT) is the second most common benign tumour of the parotid gland. The aim of this study was to assess the value of the FNAB in the diagnosis and treatment decision in patients with WT. Materials and methods We performed a retrospective study of patients treated for parotid gland mass between 2006 and 2016. Patients...
06:24
Abstract Purpose We aimed to determine the position and size of the sphenoid sinus (SS) in our study and compare the results of the measurements relative to age, gender, and the presence of pituitary adenoma using multidetector computerized tomography (MDCT). Methods We retrospectively evaluated the paranasal sinus computerized tomography (CT)...
06:24
Abstract Introduction The tissues of the laryngeal region only rarely harbor primary cartilaginous lesions, and squamous cell carcinoma remains the most frequently encountered malignant tumor in this area. Materials and Methods We reviewed the salient histological features of cartilaginous laryngeal lesions to provide differential diagnostics...
06:24
Abstract Objective To evaluate the effect of a wireless Bluetooth device (WBD) in word and sentence recognition in patients with bone conduction devices (BCDs) while using mobile phones. Methods We performed a prospective study evaluating speech and sentence recognition in both quiet and noised conditions. A total of nine patients, audiologically...
06:24
Abstract Purpose Virtual reality (VR) training of mastoidectomy is effective in surgical training—particularly if organized as distributed practice. However, centralization of practice facilities is a barrier to implementation of distributed simulation training. Decentralized training could be a potential solution. Here, we aim to assess the feasibility, use, and barriers to decentralized VR mastoidectomy training using a freeware,...
06:24
Abstract Purpose To present the utility of a smartphone-enabled otoscope as a teaching adjunct in pre-clinical otoscopy training. Methods 60 pre-clinical medical students were randomized into either a control group using a conventional otoscope or an experimental group using a smartphone-enabled otoscope. Participants in each group were trained...
06:24
Abstract Purpose To determine the minimum lymph node yield (LNY) in patients with laryngeal squamous cell carcinoma (LSCCs). Methods This retrospective study was performed in a tertiary care hospital setting and included 42 LSCC patients aged 39–81 years (females, n = 2; males, n = 40) who underwent a total or partial laryngectomy and elective...
06:24
Abstract Purpose The objective of this study was to investigate the prognostic role of three inflammatory markers: the neutrophil to lymphocyte ratio (NLR), the lymphocyte to monocyte ratio (LMR), and the platelet to lymphocyte ratio (PLR) as prognostic indicators in squamous cell carcinoma of the head and neck (HNSCC). Methods Patients with...
06:24
Abstract Purpose Eating-related problems are among the most frequent issues in olfactory impairment, causing a noticeable loss of quality of life for some of the affected persons. To what extent olfactory dysfunction impacts on the sensory perception of food is less explored. The aim of the present study was to examine the impact of olfactory dysfunction on the perception of food aromas, as well as the perception of the “basic tastes”...
06:24
Abstract Objective The purpose of this study was to investigate and summarize the characteristics of spontaneous cerebrospinal fluid rhinorrhea cases and the efficacy of transnasal endoscopic repair of spontaneous cerebrospinal fluid rhinorrhea with the assistance of computer-assisted navigation system. Methods This is a retrospective study...
06:24
Abstract Purpose Nowadays, the use of otoendoscopy is becoming increasingly popular in ear surgery. Data on endoscopic tympanoplasty are quite current but not yet sufficient. This study aims to present the anatomical and functional results of endoscopic butterfly inlay myringoplasty in large perforations. Methods The graft success rates and...
06:24
Abstract Purpose The purpose of this study was to examine the malpractice litigations pertaining to otorhinolaryngology in Japan. Methods A retrospective review was undertaken of cases tried in the Japanese civil court system during the 26-year period from 1990 to 2015 as identified in a computerized legal database. Data including patient demographics,...
06:24
Abstract Background The discomfort and complications have always been problems for nasal packing materials. This study provided a new nasal packing material called high expansion degradable cotton (HEDC). Methods Nasal endoscopic surgery was used to establish a dog model of nasal bleeding, and wound surfaces were filled with Merocel, Nasopore...
06:24
Abstract Objective Dysphagia after uncomplicated thyroidectomy is commonly reported and it includes a broad spectrum of swallowing complaints. Though various causes have been hypothesized, it remains not completely understood. Methods A systematic review was performed to identify studies concerning dysphagia post uncomplicated thyroid surgery....
06:24
Thyroid, Ahead of Print.
Mon Sep 23, 2019 10:00
Abstract Defects in DNA damage repair caused by mutations in BRCA1/2, ATM or other genes have been shown to play an important role in the development and progression of prostate cancer. The influence of such mutations on anti-tumor immunity in prostate cancer, however, is largely unknown. To better understand the correlation between BRCA1/2 mutations and the immune phenotype in prostate cancer, we characterized the immune infiltrate of eight BRCA2-mutated tumors in comparison with...
Mon Sep 23, 2019 03:00
Abstract Pancreatic cancer has been termed a ‘recalcitrant cancer’ due to its relative resistance to chemotherapy and immunotherapy. This resistance is thought to be due in part to the dense fibrotic tumor microenvironment and lack of tumor infiltrating CD8 + T cells. The gastrointestinal peptide, gastrin, has been shown to stimulate growth of pancreatic cancer by both a paracrine and autocrine mechanism. Interruption of gastrin at the CCK receptor may reduce tumor-associated fibrosis...
03:00
Cancers, Vol. 11, Pages 1418: Estrogen Receptors in Epithelial-Mesenchymal Transition of Prostate Cancer Cancers doi: 10.3390/cancers11101418 Authors: Di Zazzo Galasso Giovannelli Di Donato Bilancio Perillo Sinisi Migliaccio Castoria Prostate cancer (PC) remains a widespread malignancy in men. Since the androgen/androgen receptor (AR) axis is associated with the pathogenesis of prostate cancer, suppression of AR-dependent signaling by androgen deprivation...
Mon Sep 23, 2019 03:00
Cancers, Vol. 11, Pages 1417: Quality of Response in Acute Myeloid Leukemia: The Role of Minimal Residual Disease Cancers doi: 10.3390/cancers11101417 Authors: Maurillo Bassan Cascavilla Ciceri : In the acute myeloid leukemia (AML) setting, research has extensively investigated the existence and relevance of molecular biomarkers, in order to better tailor therapy with newly developed agents and hence improve outcomes and/or save the patient from poorly effective therapies....
Mon Sep 23, 2019 03:00
Cancers, Vol. 11, Pages 1419: Tumour Microenvironment and Immune Evasion in EGFR Addicted NSCLC: Hurdles and Possibilities Cancers doi: 10.3390/cancers11101419 Authors: Antonio Santaniello Fabiana Napolitano Alberto Servetto Pietro De Placido Nicola Silvestris Cataldo Bianco Luigi Formisano Roberto Bianco In the last few years, the treatment strategy in Non-Small Cell Lung Cancer (NSCLC) patients has been heavily modified by the introduction of the immune-checkpoint...
03:00
Future Oncology, Ahead of Print.
Mon Sep 23, 2019 13:51
Abstract We agree there was substantial heterogeneity in the design of the past abdominal aortic aneurysm (AAA) drug trials, particularly those testing antibiotics. While Yu et al. have focused on I2, it should be noted that this describes the dispersion of effect sizes and does not completely describe the heterogeneity between studies. The included antibiotic trials had many methodological variations, such as different sample sizes, durations of antibiotic administration and follow‐up protocols,...
Mon Sep 23, 2019 19:42
Sampling across tree space is one of the major challenges in Bayesian phylogenetic inference using Markov chain Monte Carlo (MCMC) algorithms. Standard MCMC tree moves consider small random perturbations of the topology, and select from candidate trees at random or based on the distance between the old and new topologies. MCMC algorithms using such moves tend to get trapped in tree space, making them slow in finding the globally most probable trees (known as 'convergence') and in estimating the correct...
Mon Sep 23, 2019 03:00
The resolution offered by genomic data sets coupled with recently developed spatially informed analyses are allowing researchers to quantify population structure at increasingly fine temporal and spatial scales. However, uncertainties regarding data set size and quality thresholds and the time scale at which barriers to gene flow become detectable have limited both empirical research and conservation measures. Here, we used restriction site associated DNA sequencing to generate a large SNP data set...
Mon Sep 23, 2019 03:00
The colour of firefly bioluminescence is primarily determined by the structure of the enzyme luciferase. To date, firefly luciferase genes have been isolated from over 30 extant species producing light ranging in colour from deep-green to orange-yellow. We have reconstructed ancestral firefly luciferase genes and characterised the enzymatic properties of the recombinant proteins in order to predict ancestral firefly light emission. Results showed that the synthetic luciferase for the last common...
Mon Sep 23, 2019 03:00
The current influenza A antigenic evolution paradigm suggesting that antigenic evolution is highly constrained, with successful new viruses being near optimal at maximizing their antigenic distance from past strains. This begs the question of whether influenza antigenic evolution is fundamentally predictable, or if it takes place on a much higher dimensional antigenic space with multiple possible trajectories. We tackle this issue by building a genotype to phenotype map validated on historical hemagglutination...
Mon Sep 23, 2019 03:00
The allocation of resources to the production of one sex or another has been observed in a large variety of animals. Its theoretical basis allows accurate predictions of offspring sex ratios in many species, but the mechanisms by which sex allocation is controlled are poorly understood. Using previously published data we investigated if alternative splicing, combined with differential expression, were involved with sex allocation in the parasitoid wasp, Nasonia vitripennis. We found that sex allocation...
Mon Sep 23, 2019 03:00
The origin of eukaryotes is one of evolution's most important transitions, yet it is still poorly understood. Evidence for how it occurred should be preserved in eukaryotic genomes. Based on phylogenetic trees from ribosomal RNA and ribosomal proteins, eukaryotes are typically depicted as branching together with or within archaea. This ribosomal affiliation is widely interpreted as evidence for an archaeal origin of eukaryotes. However, the extent to which the archaeal ancestry of genes for the cytosolic...
Mon Sep 23, 2019 03:00
The origins of multicellular physiology are tied to evolution of gene expression. Genes can shift expression as organisms evolve, but how ancestral expression influences altered descendant expression is not well understood. To examine this, we amalgamated 1,903 RNA-seq datasets from 182 research projects, including 6 organs in 21 vertebrate species. Quality control eliminated project-specific biases, and expression shifts were reconstructed using gene-family-wise phylogenetic Ornstein-Uhlenbeck models....
Mon Sep 23, 2019 03:00
The repeatability of adaptive radiation is expected to be scale dependent, with determinism decreasing as greater spatial separation among ''replicates'' leads to their increased genetic and ecological independence. Threespine stickleback (Gasterosteus aculeatus) provide an opportunity to test whether this expectation holds for the early stages of adaptive radiation -their diversification in freshwater ecosystems has been replicated many times. To better understand the repeatability of that adaptive...
Mon Sep 23, 2019 03:00
Evolutionary theory suggests that phenotypic stasis is explained by natural selection or by constraints imposed by mutation and recombination of standing genetic variation. We performed experimental evolution from standing genetic variation with the nematode Caenorhabditis elegans, measuring locomotion behavior in outcrossing populations for 240 generations. We find that in our constant environment locomotion shows no directional divergence, due to both stabilizing and disruptive selection on specific...
Mon Sep 23, 2019 03:00
In many animals, mate choice is important for the maintenance of reproductive isolation between species. Traits important for mate choice and behavioural isolation are predicted to be under strong stabilising selection within species, however such traits can also exhibit variation at the population level driven by neutral and adaptive evolutionary processes. Here, we describe patterns of divergence among androconial and genital chemical profiles at inter- and intra-specific levels in mimetic Heliconius...
Mon Sep 23, 2019 03:00
The elemental composition of organisms relates to a suite of functional traits that change during development in response to environmental conditions. It may be a part of a phenomenon known as developmental programming, which hypothetically creates phenotypes that are better adapted to their environments. However, associations between developmental speed and elemental body composition are not well understood. We compared body mass, elemental body composition, food uptake and fat metabolism of Drosophila...
Mon Sep 23, 2019 03:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου