Abstract Pancreatic cancer has been termed a ‘recalcitrant cancer’ due to its relative resistance to chemotherapy and immunotherapy. This resistance is thought to be due in part to the dense fibrotic tumor microenvironment and lack of tumor infiltrating CD8 + T cells. The gastrointestinal peptide, gastrin, has been shown to stimulate growth of pancreatic cancer by both a paracrine and autocrine mechanism. Interruption of gastrin at the CCK receptor may reduce tumor-associated fibrosis...
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Abstract Defects in DNA damage repair caused by mutations in BRCA1/2, ATM or other genes have been shown to play an important role in the development and progression of prostate cancer. The influence of such mutations on anti-tumor immunity in prostate cancer, however, is largely unknown. To better understand the correlation between BRCA1/2 mutations and the immune phenotype in prostate cancer, we characterized the immune infiltrate of eight BRCA2-mutated tumors in comparison with...
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Metabolic Syndrome and Related Disorders, Ahead of Print.
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Microbial Drug Resistance, Ahead of Print.
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Microbial Drug Resistance, Ahead of Print.
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Microbial Drug Resistance, Ahead of Print.
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Microbial Drug Resistance, Ahead of Print.
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They ’ve been called the “special forces” of the immune system: invariant natural killer T cells. Although there are relatively few of them in the body, they are more powerful than many other immune cells.In experiments with mice, UCLA researchers have shown they can harness the power of iNKT cells to attack tumor cells and treat cancer.The new method, described in the journal Cell Stem Cell, suppressed the growth of multiple types of human tumors that had been transplanted into the animals. “What’s...
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GYN Oncology of Central New York, Mary J Cunningham, MD and W Douglas Bunn, MD, join Upstate Medical University ’s Department of Obstetrics and Gynecology and become part of the services offered through the Upstate Cancer Center. (Source: SUNY Upstate Medical)
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The results of the 2018 national cancer patient experience survey revealed overall experience is very positive, with patients rating it at an average of 8.8 out of 10. (Source: NHS Networks)
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The fundraiser highlights the fifth anniversary of the Upstate Cancer Center. (Source: SUNY Upstate Medical)
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Vitrakvi® (larotrectinib) receives first tumor-agnostic approval in EUPrecision oncology treatment Vitrakvi® (larotrectinib) approved for the treatment of adults and children with locally advanced or metastatic solid tumors that have a rare genomic alteration called an NTRK gene fusion / Vitrakvi, which was exclusively designed to treat TRK fusion cancer, is the first therapy in the EU with a tumor-agnostic indication / Larotrectinib provides high response rates and durable responses in adults and...
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AUSTIN, TX - An artificial intelligence (AI) algorithm could cut in half the...Read more on AuntMinnie.comRelated Reading: AI shows promise for reducing mammography workload AI enhances radiologist performance for DBT Deep learning enhances breast cancer risk assessment SBI: AI improves DBT's performance in dense tissue AI can reduce mammography screening's workload (Source: AuntMinnie.com Headlines)
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Precision oncology treatment Vitrakvi ® (larotrectinib) approved for the treatment of adults and children with locally advanced or metastatic solid tumors that have a rare genomic alteration called an NTRK gene fusion / Vitrakvi, which was exclusively designed to treat TRK fusion cancer, is the first therapy in the EU with a tumor-agno stic indication / Larotrectinib provides high response rates and durable responses in adults and children with TRK fusion cancer, including primary CNS tumors and...
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Stool DNA test offers a sensitive, noninvasive, at-home option to screen for colorectal cancer, second deadliest cancer in U.S. MADISON, Wis., Sept. 23, 2019 -- (Healthcare Sales & Marketing Network) -- Exact Sciences Corp. (NASDAQ: EXAS) announced tod... Diagnostics, Oncology, FDA Exact Sciences, Cologuard, colorectal cancer, cancer screening (Source: HSMN NewsFeed)
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MONDAY, Sept. 23, 2019 -- Male breast cancer patients have higher mortality after cancer diagnosis than female patients, according to a study published online Sept. 19 in JAMA Oncology. Fei Wang, M.D., Ph.D., from the Vanderbilt University Medical... (Source: Drugs.com - Pharma News)
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MONDAY, Sept. 23, 2019 -- Nonsteroidal anti-inflammatory drugs (NSAIDs) are correlated with better overall survival in patients with head and neck squamous cell carcinoma (HNSCC), and there is a nonsignificant benefit for aspirin use in non-small... (Source: Drugs.com - Pharma News)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
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MONDAY, Sept. 23, 2019 -- For patients with advanced lung cancer, palliative care is associated with increased survival when it is received 31 to 365 days after cancer diagnosis, according to a study published online Sept. 19 in JAMA... (Source: Drugs.com - Pharma News)
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Onions and garlic are key ingredients in sofrito, a condiment that's a staple of Puerto Rican cuisine. They may also be a recipe for reducing the risk of breast cancer. That's according to the findings of a study led by University at Buffalo and University of Puerto Rico researchers. It's the first population-based study to examine the association between onion and garlic consumption and breast cancer in Puerto Rico. (Source: World Pharma News)MedWorm Message: Have you tried our new medical search...
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Final overall survival in breast cancer, immunotherapy in ever-earlier settings, and novel strategies for rare tumor subgroups will be some of the data revealed at Europe's largest oncology meeting.Medscape Medical News (Source: Medscape Medical News Headlines)
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Bryan Marquez, 10, from San Antonio, Texas, started having trouble walking and was limping. He was diagnosed this year with a rare bone cancer known as Ewing sarcoma. (Source: the Mail online | Health)
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Low-dose aspirin may improve survival odds for patients battling head/neck and lung cancer, two new studies suggest. (Source: WebMD Health)
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Patients with advanced colon cancer face a lower risk of developing long-term peripheral sensory neuropathy (PSN) with a three-month rather than a six-month regimen of oxaliplatin-based adjuvant chemotherapy, according to results from the ACHIEVE phase 3 trial.Reuters Health Information (Source: Medscape Medical News Headlines)
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The drugs can attack a range of cancers, rather than those in just one part of the body. (Source: BBC News | Health | UK Edition)
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Four small friends who met in the hospital while getting treated for cancer are back together for a group photo. (Source: WebMD Health)
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PROSTATE cancer symptoms usually don ’t show until the cancer has progressed, which is why recognising signs when they begin to appear is very important. Most symptoms become apparent when a man goes to the toilet. (Source: Daily Express - Health)
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Jemily Brown, 35, from Sandhurst in Surrey, was diagnosed with pseudomyxoma peritonei in September 2017. She had surgery to remove six litres of fluid in October 2017. (Source: the Mail online | Health)
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WARNING: GRAHPIC CONTENT. Rebekah Rupp, 41, from Morrison, Oklahoma, started using the machines in her teens and loved the confidence that having a bronzed glow gave her. (Source: the Mail online | Health)
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Read clinically focused news coverage of key developments from ESMO 2019Medscape Oncology (Source: Medscape Today Headlines)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
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MONDAY, Sept. 23, 2019 -- Low-dose aspirin may improve survival odds for patients battling head/neck and lung cancer, two new studies suggest. The first reviewed data on 460 patients with head and neck squamous cell carcinoma (HNSCC) or early stage... (Source: Drugs.com - Daily MedNews)
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There is little a person can do to prevent it, and there is nothing comparable to mammography or colonoscopy to screen for it when it is most amenable to cure. (Source: NYT Health)
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Biosimilars are safe and effective medications for treating, many illnesses such as arthritis, and cancer. Learn about biosimilars and how they benefit patients. (Source: FDA Center for Drug Evaluation and Research - What's New)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
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It's the fifth recall by Torrent of losartan-containing medicines due to detection of unacceptable levels of a potential carcinogen.News Alerts (Source: Medscape Cardiology Headlines)
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A single fraction of high-dose radiation provides better and more durable pain control than standard radiotherapy in patients with mostly non-spine bone metastases.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
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Benefit not significant for aspirin use in patients with non - small cell lung cancer undergoing SBRT (Source: The Doctors Lounge - Oncology)
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Clinical characteristics, undertreatment correlated with 63.3 percent excess mortality rate for men (Source: The Doctors Lounge - Oncology)
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(Source: Karmanos Cancer Institute)
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The instability of medical knowledge, especially in oncology, often leads to therapeutic decisions that lead to regret down the road, as this case study highlights.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
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