Publication date: Available online 31 August 2019Source: Allergology InternationalAuthor(s): Risa Yoshihara, Toshihiko Komai, Yasuo Nagafuchi, Yumi Tsuchida, Hirofumi Shoda, Mariko Tanaka, Tetsuo Ushiku, Keishi Fujio
Publication date: Available online 29 August 2019Source: Allergology InternationalAuthor(s): Tomonobu Ito, Tomoko Kobayashi, Chizu Egusa, Tatsuo Maeda, Namiko Abe, Yukari Okubo, Ryoji Tsuboi, Tomoyuki Niitsuma
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Abstract Nonsteroidal anti‐inflammatory drugs (NSAIDs), the medications most commonly used for treating pain and inflammation, are the main triggers of drug hypersensitivity reactions. The latest classification of NSAIDs‐hypersensitivity by the European Academy of Allergy and Clinical Immunology (EAACI) differentiates between cross‐hypersensitivity reactions (CRs), associated with COX‐1 inhibition, and selective reactions, associated with immunological mechanisms. Three phenotypes fill into the...
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Asthma is recognized as a major public health concern in the world. The aim of this investigation was to evaluate the prevalence of asthma by using the Global Allergy and Asthma Network of Excellence (GA2LEN) que...
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Publication date: Available online 30 August 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Leonard B. Bacharier, Akio Mori, Hirohito Kita
Publication date: Available online 30 August 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Catherine R. Weiler, K. Frank Austen, Cem Akin, Marla S. Barkoff, Jonathan A. Bernstein, Patrizia Bonadonna, Joseph H. Butterfield, Melody Carter, Charity C. Fox, Anne Maitland, Thanai Pongdee, S Shahzad Mustafa, Anupama Ravi, Mary C. Tobin, Harissios Vliagoftis, Lawrence B. SchwartzAbstractOur current recommendations for diagnosing and treating primary MCAS make use of the latest studies...
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The full range of allergic reactions to Total Parenteral Nutrition (TPN) remains unknown. Additionally, beyond individual allergens, there may be other factors contributing to TPN hypersensitivity reactions.
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In the article “Perinatal influences on the development of asthma and atopy in childhood” by Illi S et al (Ann Allergy Asthma Immunol;2014:132-139.e1) a disclosure was inadvertently left out of the article. The following disclosure should have been added: Dr von Mutius is listed as inventor on the following patents: Publication number EP 1411977—Composition containing bacterial antigens used for the prophylaxis and the treatment of allergic diseases; Publication number EP1637147—Stable dust extract...
Alveolar macrophages are the most numerous immune cell in the lung.1 Moreover, macrophages have a significant effect on the pathogenesis of asthma2; however, they have been clinically limited in their usefulness despite their potential role as biomarkers or targets for specifically designed therapeutics. Currently, several biologic therapies target eosinophilic or allergic asthma, but no current therapy specifically targets macrophages despite their ubiquity in the lungs.
When parents first learn that their child has asthma, they often ask whether the child will ever outgrow it. From the time of initial diagnosis, parents are already thinking about prognosis. Another common question is whether the child can still play sports and exercise, which addresses long-term management and daily limitations. However, few parents ask whether we can predict how often their child will experience exacerbations. Although poorly controlled asthma disrupts sleep and activity, exacerbations...
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Abstract Background Helicobacter pylori neutrophil‐activating protein (NAP) is an immune modulator with anti‐Th2 inflammation activity that can be used to prevent IgE‐mediated allergic reactions. Cholera toxin B (CTB) is a mucosal adjuvant that can induce antigen tolerance. Bacillus subtilis spores are an ideal vehicle for the oral delivery of heterologous antigens. Objective We investigated the therapeutic effect of recombinant NAP B. subtilis spores on peanut allergies in a mouse model....
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Publication date: September 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 3Author(s):
Publication date: September 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 3Author(s):
Publication date: September 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 3Author(s): David Stukus
Publication date: September 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 3Author(s): Jonathan S. Tam
Publication date: September 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 3Author(s):
Publication date: September 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 3Author(s):
Publication date: September 2019Source: Annals of Allergy, Asthma & Immunology, Volume 123, Issue 3Author(s):
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