Abstract Background Temporomandibular disorders (TMD) include pain and dysfunction in masticatory muscles and temporomandibular joints (TMJs). Applied relaxation (AR) is a coping skill that may be applicable for treatment of TMD. Objectives The aim of this randomized, controlled study was to evaluate the effectiveness of AR as compared to stabilization splint (SS), for treatment of TMD during 12‐month follow‐up. Methods The data was derived from 96 university students seeking treatment...
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Related ArticlesOperative start time may impact the quality of mesorectal excision in minimally invasive rectal surgery: retrospective analysis of 137 patients. G Chir. 2019 May-Jun;40(3):163-169 Authors: Valverde A, Akkari I, Sezeur A, Goasguen N, Cahais J, Oberlin O, Flejou JF, Lupinacci RM Abstract INTRODUCTION: Timing of major elective operations is a potentially important outcome variable. This study examined the impact of operative start time (OST)...
Related ArticlesRoutinary use of fibrin sealants to prevent prolonged air leak in thoracic surgery: our experience. G Chir. 2019 May-Jun;40(3):170-173 Authors: Porrello C, Iadicola D, Grutta EM, Palazzolo M, Vaglica A, Gagliardo C, Giangregorio F, Gulotta E, Lo Faso F, Gullo R, Carini F, Tomasello G, Cocorullo G Abstract INTRODUCTION: Prolonged air leak (PAL) is one of the most common postoperative complications after lung surgery. It is associated with...
Related ArticlesIONM and thyroidectomy in benign thyroid disease. Analysis of adverse events. G Chir. 2019 May-Jun;40(3):174-181 Authors: Del Rio P, Cozzani F, Puteo N, Loderer T, Rossini M, Bonati E Abstract OBJECTIVES: The aim of this study is to identify statistically significant differences in the onset of postoperative complications in patients undergoing thyroid surgery for benign pathology, following the systematic introduction of intraoperative...
Related ArticlesOutpatient management of proctologic disease. Which techniques for local anesthesia? The experience of a single center. G Chir. 2019 May-Jun;40(3):182-187 Authors: Falco N, Tutino R, Fontana T, Gullo R, Licari L, Raspanti C, De Marco P, Colli F, Venturelli P, Salamone G, Cocorullo G Abstract INTRODUCTION: Since 1899 outpatient management of surgical patients had been increasing, becoming the best option when possible. In 1988 was described...
Related ArticlesA rare case of life-threatening extra-peritoneal bleeding a. G Chir. 2019 May-Jun;40(3):188-192 Authors: Popivanov G, Vasilev V, Cirocchi R, Kjossev K, Tabakov M, Penkov M, Mutafchiyski V Abstract INTRODUCTION: Although inguinal hernia repair is a routine procedure and frequently performed as one-day surgery, we should be particularly aware of the possible complications, which could be life-threatening if not recognized in due course....
Related ArticlesMirizzi syndrome: a challenging diagnosis. Case report. G Chir. 2019 May-Jun;40(3):193-198 Authors: Hassan R, Solinas L, Notarangelo M, Sagnotta A, Giubilo C, Battaglia B, Di Cosimo C, Mancini S Abstract Mirizzi Syndrome (MS) is an uncommon complication of chronic gallstone disease defined as a common bile duct (CBD) obstruction secondary to gallstone impaction in the cystic duct or gallbladder neck. MS is still a challenging clinical...
Related ArticlesStruma ovarii complicating pregnancy. Case report and literature review. G Chir. 2019 May-Jun;40(3):199-207 Authors: Pepe F, Valenti O, Insalaco G, Zigarelli MMG, Pepe L, Piana M Abstract A 19-year-old woman at 12th week of pregnancy was referred to our hospital with severe acute abdominal pain, nausea and vomiting. Patient's abdomen was untreatable. Routine examinations, except neutrophilic leukocytosis, were normal. Ultrasound imaging...
Related ArticlesResection of a giant mediastinal leiomyosarcoma. G Chir. 2019 May-Jun;40(3):208-212 Authors: Porrello C, Gullo R, Gagliardo CM, Vaglica A, Palazzolo M, Giangregorio F, Iadicola D, Gulotta E, Mannino V, Lo Faso F, Tomasello G, Carini F, Cocorullo G Abstract Primary leiomyosarcomas of the lung are tumors. We report a case of 49-year old female with history of cough, breathless at rest, right sided chest pain. Chest CT showed a huge (16...
Related ArticlesPseudomixoma peritonei associated with appendiceal cistoadenoma rupture: case report. G Chir. 2019 May-Jun;40(3):213-216 Authors: Solinas L, Sagnotta A, Chessa A, Fiorini A, Battaglia B, Di Cosimo C, Notarangelo MG, Hassan R, Leone L, Mancini S Abstract Appendiceal mucocele represents specimen finding in 0.2-0.3% out of appendectomies. The rupture or perforation in peritoneal cavity might cause pseudomixoma peritonei (PMP), with multiple...
Related ArticlesA rare case of renal tumor in children: clear cell sarcoma. G Chir. 2019 May-Jun;40(3):217-224 Authors: Brillantino C, Rossi E, Minelli R, Irace D, Castelli L, Zeccolini R, Bignardi E, Tufano A Abstract Clear cell sarcoma of the kidney is an uncommon renal neopla sm of childhood. It represents about 4% of childhood malignant neoplasms and is generally more common in children under 5 years of age. In the present article, we describe the...
Related ArticlesSecond jejunal loop adenocarcinoma associated with celiac disease: the first case report. G Chir. 2019 May-Jun;40(3):225-229 Authors: Ursi P, Tarallo M, Crocetti D, Cavallaro G, Fiori E, D'Andrea V, De Toma G Abstract INTRODUCTION: Jejunal adenocarcinoma is a very rare disease but the frequency of this rare carcinoma is higher in celiac patients. We report the first case report of a second jejunal loop adenocarcinoma associated with celiac...
Related ArticlesIntestinal perforation secondary to blunt abdominal trauma in pre-existing inguinal hernia. G Chir. 2019 May-Jun;40(3):230-233 Authors: Cartanese C, Guastadisegno C, Magli M, Franco F, Frattini P, Buonfantino M Abstract Inguinal hernias are very common in men. We report a rare case of intestinal perforation following blunt abdominal trauma in a 80-year-old man with pre-existing inguinal hernia. A careful and serial physical examination,...
Related ArticlesUnusual presentation of metastatic thyroid cancer without a primary: role of diagnostic imaging in a daily clinical setting. G Chir. 2019 May-Jun;40(3):234-237 Authors: Izzo L, Pugliese F, Di Poce I, Valabrega S, Di Cello P, Gabriele R, Messineo D, Izzo S, Izzo P Abstract Papillary thyroid carcinoma (PTC) is the most common mali gnancy of the thyroid gland. In 21-90% of the patients occult lymph node metastases may occur. The case reported...
Related ArticlesA very rare cause of retroperitoneal bleeding in young patients: do not forget the occurrence of a ruptured left gastroepiploic artery aneurysm! G Chir. 2019 May-Jun;40(3):238-242 Authors: Sinagra E, Buscaglia F, Giganti A, Bono V, Di Grusa D, Sciumè C Abstract Visceral artery aneurysms represent a very rare condition. The affected patients usually present as emergency secondary to the sudden rupture of the aneurysm or as an incidental...
Related ArticlesAn atypical sternoclavicular septic arthritis that was treated conservatively. G Chir. 2019 May-Jun;40(3):243-247 Authors: Yeak RDK, Hussin P, Yap YY, Nizlan NM Abstract Sternoclavicular joint infection is rare. While it is usually treated surgically, we wish to report a case of non-operative treatment of such infection caused by an atypical organism. A 51-year-old woman, known case of diabetes mellitus, hypertension, dyslipidaemia and...
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Abstract Background There is evidence that physical exercise training (PET) conducted at the workplace is effective in improving physical fitness and thus health. However, there is no current systematic review available that provides high-level evidence regarding the effects of PET on physical fitness in the workforce. Objectives To quantify sex-, age-, and...
Abstract Background Increases in maximal oxygen uptake (VO2max) are strongly associated with improved cardiovascular health. Objective The aim was to perform a systematic review and meta-analysis to determine whether VO2max responses to endurance training (ET), the most effective intervention to improve VO2max, are influenced by sex. ...
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Abstract This study aimed to compare the surface topographies and nanoscale profiles of intact and used WaveOne, WaveOne Gold, Reciproc, and Reciproc blue nickel–titanium (NiTi) instruments. Sixteen NiTi instruments were evaluated; four from each one of WaveOne (25/0.08), WaveOne Gold (25/0.07), Reciproc (25/0.08), and Reciproc blue (25/0.08) files. Each instrument was used to prepare four curved canals. A three-dimensional nanoscale surface profiler was used to assess instrument...
Abstract This study assessed the antibacterial activity of BioRoot RCS in comparison with that of the Totalfill BC and AH Plus sealers against Enterococcus faecalis biofilms in dentinal tubules using confocal laser-scanning microscopy. Sixty-six root dentin halves were prepared and sterilized. Three sections were used to ensure sterilization. The remaining were inoculated with E. faecalis. Three specimens were examined to verify the viability of biofilms. The sixty specimens...
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Abstract Differentiation potential of stem cells into various lineages makes these cells as promising sources to treat multiple diseases. In this regard, the use of different strategies and protocols to increase differentiation capacity is highly demanded. Low-level laser therapy, a relatively noninvasive technique, has the capacity to accelerate the healing of numerous injuries and a portion of restorative capacity could be correlated with the stem cell activation and differentiation....
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Abstract Upsurge in the instances of antibiotic-resistant uropathogenic Escherichia .coli (UPECs) strains has repositioned the attention of researchers towards a century old antimicrobial approach popularly known as phage therapy. Rise of extended spectrum beta lactamase (ESBL) and biofilm producing strains has added another step of hurdle in treatment of uropathogens with conventional antibiotics, thus providing a further impetus for search for exploring new therapeutic measures....
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Abstract Purpose of Review HIV treatment simplification is typically indicated for virologically suppressed patients with no baseline resistance-associated mutations (RAMs) or prior virologic failure (VF) to the simplification regimen. Simplification can occur to minimize pill burden, toxicities, drug-drug interactions, or costs. As most studies for treatment simplification excluded patients with baseline RAMs or prior VF, this review...
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Related ArticlesOne-week, but not 12-hours, cast immobilization alters promotor DNA methylation patterns in the nNOS gene in mouse skeletal muscle. J Physiol. 2019 Sep 06;: Authors: Tomiga Y, Ito A, Sudo M, Ando S, Eshima H, Sakai K, Nakashima S, Uehara Y, Tanaka H, Soejima H, Higaki Y Abstract KEY POINTS: DNA methylation may play an important role in regulating gene expression in skeletal muscle to adapt to physical activity and inactivity. Neuronal...
Related ArticlesmitoRACE: evaluating mitochondrial function in vivo and in single cells with subcellular resolution using multiphoton NADH autofluorescence. J Physiol. 2019 Sep 06;: Authors: Willingham TB, Zhang Y, Andreoni A, Knutson JR, Lee DY, Glancy B Abstract KEY POINTS: We developed a novel metabolic imaging approach that provides direct measures of the rate of mitochondrial energy conversion with single-cell and subcellular resolution by evaluating...
Related ArticlesFrom atoms to physiology: What it takes to really understand inflammasomes. J Physiol. 2019 Sep 06;: Authors: Schmidt FI Abstract Rapid inflammatory responses to cytosolic threats are mediated by inflammasomes - large macromolecular signalling complexes that control the activation of the pro-inflammatory cytokines IL-1β and IL-18, as well as cell death by pyroptosis. Different inflammasome sensors are activated by diverse direct and indirect...
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Related ArticlesRisk Factors for Obstructive Sleep Apnea Syndrome in Children: State of the Art. Int J Environ Res Public Health. 2019 Sep 04;16(18): Authors: Gulotta G, Iannella G, Vicini C, Polimeni A, Greco A, de Vincentiis M, Visconti IC, Meccariello G, Cammaroto G, De Vito A, Gobbi R, Bellini C, Firinu E, Pace A, Colizza A, Pelucchi S, Magliulo G Abstract The obstructive sleep apnea syndrome (OSAS) represents only part of a large group of pathologies...
Related ArticlesThe Most Effective Amount of Forward Movement for Oral Appliances for Obstructive Sleep Apnea: A Systematic Review. Int J Environ Res Public Health. 2019 Sep 04;16(18): Authors: Sakamoto Y, Furuhashi A, Komori E, Ishiyama H, Hasebe D, Sato K, Yuasa H Abstract This systematic review clarifies the amount of effective protrusion in mandibular advancement devices of oral appliances required for obstructive sleep apnea (OSA). The systematic...
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Related ArticlesSystematic review of the use of pentoxifylline and tocopherol for the treatment of medication-related osteonecrosis of the jaw. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Aug 14;: Authors: Heifetz-Li JJ, Abdelsamie S, Campbell CB, Roth S, Fielding AF, Mulligan JP Abstract OBJECTIVE: Medication-related osteonecrosis of the jaw (MRONJ) is a pathologic process resulting in progressive destruction of the jaws. There are no established...
Related ArticlesAssociation between salivary secretary function and laryngopharyngeal reflux: a prospective study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Aug 13;: Authors: Kim JW, Kim HJ, Park KI, Kim YM, Choi JS Abstract OBJECTIVES: This study aimed to demonstrate the prevalence and risk factors of laryngopharyngeal reflux (LPR) in patients with xerostomia and to investigate the association between salivary function and LPR. STUDY...
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Related ArticlesSensory Prediction Errors Are Less Modulated by Global Context in Autism Spectrum Disorder. Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 08;3(8):667-674 Authors: Goris J, Braem S, Nijhof AD, Rigoni D, Deschrijver E, Van de Cruys S, Wiersema JR, Brass M Abstract BACKGROUND: Recent predictive coding accounts of autism spectrum disorder (ASD) suggest that a key deficit in ASD concerns the inflexibility in modulating local prediction...
Related ArticlesNeurite architecture of the planum temporale predicts neurophysiological processing of auditory speech. Sci Adv. 2018 07;4(7):eaar6830 Authors: Ocklenburg S, Friedrich P, Fraenz C, Schlüter C, Beste C, Güntürkün O, Genç E Abstract The left hemispheric advantage in speech perception is reflected in faster neurophysiological processing. On the basis of postmortem data, it has been suggested that asymmetries in the organization of the intrinsic...
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Related ArticlesNeuromodulatory effects of pudendal nerve stimulation on bladder hypersensitivity are present in opioid-pretreated rats. Reg Anesth Pain Med. 2019 Sep 04;: Authors: Ness TJ, McNaught J, Clodfelder-Miller B, Nelson DE, Su X Abstract BACKGROUND AND OBJECTIVES: Bilateral electrical pudendal nerve stimulation (bPNS) reduces bladder hypersensitivity in rat models and anecdotally reduces pain in humans with pelvic pain of urologic origin. Concomitant...
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Related ArticlesMyocardin regulates mitochondrial calcium homeostasis and prevents permeability transition. Cell Death Differ. 2018 11;25(10):1732-1748 Authors: Mughal W, Martens M, Field J, Chapman D, Huang J, Rattan S, Hai Y, Cheung KG, Kereliuk S, West AR, Cole LK, Hatch GM, Diehl-Jones W, Keijzer R, Dolinsky VW, Dixon IM, Parmacek MS, Gordon JW Abstract Myocardin is a transcriptional co-activator required for cardiovascular development, but also...
Related ArticlesSGLT6 - A pharmacological target for the treatment of obesity? Adipocyte. 2018;7(4):277-284 Authors: Baader-Pagler T, Eckhardt M, Himmelsbach F, Sauer A, Stierstorfer BE, Hamilton BS Abstract Despite increased knowledge of nutrient intake regulation and energy homeostasis, treatment options for obesity remain limited. Food reward consists of two branches: gustatory and post-ingestive nutritive information. Drosophila lacking dSLC5A11...
Related ArticlesOptogenetic sensors in the zebrafish heart: a novel in vivo electrophysiological tool to study cardiac arrhythmogenesis. Theranostics. 2018;8(17):4750-4764 Authors: van Opbergen CJM, Koopman CD, Kok BJM, Knöpfel T, Renninger SL, Orger MB, Vos MA, van Veen TAB, Bakkers J, de Boer TP Abstract Cardiac arrhythmias are among the most challenging human disorders to diagnose and treat due to their complex underlying pathophysiology. Suitable...
Neulasta Regimen for the Hematopoietic Acute Radiation Syndrome: Effects Beyond Neutrophil Recovery.
Related ArticlesNeulasta Regimen for the Hematopoietic Acute Radiation Syndrome: Effects Beyond Neutrophil Recovery. Int J Radiat Oncol Biol Phys. 2019 03 15;103(4):935-944 Authors: Legesse B, Kaur A, Kenchegowda D, Hritzo B, Culp WE, Moroni M Abstract PURPOSE: Understanding the physiopathology underlying the acute radiation syndrome (ARS) and the mechanism of action of drugs known to ameliorate ARS is expected to help identify novel countermeasure...
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Abstract Objectives Food insecurity (FI) has serious academic, social, and physical health consequences for children. A recent clinical recommendation suggests FI screening during child well visits. While FI screening research has considered clinician feedback, little is known about caregivers’ experience of disclosing FI to health care providers. Our paper explores caregivers’ barriers and facilitators to FI disclosure. ...
Abstract Objectives Parents of young children have unique informational needs and it has been demonstrated that information-seeking behaviors influence health outcomes. Due to social media’s popularity, understanding parents’ use of social media may assist in disseminating accurate parenting information and in developing targeted interventions. Thus, we aimed to identify and describe the existing literature of parental use of social...
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