[Cycloferon efficacy in treatment of upper respiratory tract infections: systematic review and meta-analysis].
[Article in Russian; Abstract available in Russian from the publisher]
Mazina NK1, Mazin PV1, Khafisianova RK2.
Author information
1
Kirov state medical university, Kirov, Russia, 610998.
2
Kazan state medical university, Kazan, Russia, 420012.
Abstract
Medical scientific sources about randomized clinical trials of Cycloferon were studied as a single plot of 531 articles. AIM was to get the generalized cycloferon efficacy's assessment in comparison with basic therapies curing the otorhinolaryngologic diseases. Groups heterogeneity and responding parameters' variability were estimated also. Comparison groups were symmetric enough to annihilate end-point variabilities, so the results' interpretations were clear enough and vector of clinical effects was detectable. Comparison groups were integrated to increase statistical power of metaanalysis. In result, cycloferon additional administration in treatment of otorhinolaryngologic diseases added 25% to absolute and relative usefulness of medical intervention. Also cycloferon increased 3,5 times the chances of recovery and absence of recurrent exacerbation.

KEYWORDS:
chance ratio; cycloferon; end-points; heterogeneity analysis; meta-analysis; otorhinolaryngologic diseases; sensitivity analysis

PMID: 31486434 DOI: 10.17116/otorino20198403182
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Select item 31486433
2.
Vestn Otorinolaringol. 2019;84(3):74-81. doi: 10.17116/otorino20198403174.
[Opportunistic fungal infections of ent organs. Part 2].
[Article in Russian; Abstract available in Russian from the publisher]
Bezshapochnyy SB1, Zachepylo SV1, Polianskaya VP1, Bobrova NA1, Fedorchenko VI1.
Author information
1
Higher State Educational Establishment of Ukraine 'Ukrainian Medical Stomatological Academy', Poltava, Ukraine, 36000.
Abstract
The review of literature summarized information about main fungal pathogens and theirs proportions in infections affecting the ENT areas. Different nosological forms of fungal diseases of upper respiratory tract and ear were considered, and listed the main clinical manifestations. Microbiological diagnosis of mycoses affecting the ENT organs is based on microscopic, mycological, immunological and molecular-genetic studies. The review paid particular attention to the treatment of fungal infections of the areas. It presented the classification of modern antifungal drugs, and described regimens and duration of treatment depending on fungus type, disease severity and other patient's condition. It was noted that success of therapy of fungal infections affecting upper respiratory tract and ear now provided by using of complex antimycotics, immunotropic agents, antihistamines and probiotics. The emergence of resistant strains of micromycetes was observed as the main reason for decreased effectiveness of antifungal agents. Prospective solution of this problem were indicated by way of using of biologically active plant compounds, nanoantiseptics, metal ions, enzymes and photodynamic therapy. The review suggested relevance of increasing rates of fungal morbidity affecting the ENT areas, the necessity of early diagnosis, the search of new antifungal agents and compounds with fungicidal activity and theirs introduction into clinical practice.

KEYWORDS:
antifungal agents; diagnostics; fungal infections of ENT organs; resistant strains

PMID: 31486433 DOI: 10.17116/otorino20198403174
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Select item 31486432
3.
Vestn Otorinolaringol. 2019;84(3):68-73. doi: 10.17116/otorino20198403168.
[Angioneurotic edema. Classification, diagnosis, prophylaxis, treatment tactics].
[Article in Russian; Abstract available in Russian from the publisher]
Kryukov AI1, Kunelskaya NL1, Tsarapkin GY2, Tovmasyan AS2, Lapchenko AA3, Kishinevskii AE2, Gorovaya EV2, Aleksanyan TA2.
Author information
1
Sverzhevsky Clinical Research Institute of Otorhinolaryngology, Moscow, Russia, 117152; Pirogov Russian National Research Medical University, Moscow, Russia, 117997.
2
Sverzhevsky Clinical Research Institute of Otorhinolaryngology, Moscow, Russia, 117152.
3
Pirogov public Moscow city hospital #1, Moscow, Russia, 117049.
Abstract
The article highlights the current understanding of the etiology and various mechanisms of development, patterns of angioneurotic edema. Detailed clinical and laboratory picture of allergic and non-allergic forms of angioedema are presented.

KEYWORDS:
Quincke's edema; angioneurotic edema; bradykinin; complement

PMID: 31486432 DOI: 10.17116/otorino20198403168
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Select item 31486431
4.
Vestn Otorinolaringol. 2019;84(3):65-67. doi: 10.17116/otorino20198403165.
[A rare observation of amyloidosis of the larynx simulating a tumor].
[Article in Russian; Abstract available in Russian from the publisher]
Popadyuk VI1, Novozhilova EN2, Fedotov AP3, Chernolev AI1, Korshunova IA1, Olyshanskaya OV4, Bitsaeva AV1.
Author information
1
Peoples' Friendship University of Russia, Moscow, Russia, 117198.
2
Peoples' Friendship University of Russia, Moscow, Russia, 117198; Moscow City Cancer Hospital #62, Moscow region, Russia, 143423.
3
Moscow City Cancer Hospital #62, Moscow region, Russia, 143423.
4
First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow, Russia, 119991.
Abstract
Presented a clinical case of a rare localization amyloidosis of the larynx, simulating a tumor. Considered the features of diagnosis and treatment of this disease.

KEYWORDS:
amyloidosis; amyloidosis of the larynx

PMID: 31486431 DOI: 10.17116/otorino20198403165
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Select item 31486430
5.
Vestn Otorinolaringol. 2019;84(3):61-64. doi: 10.17116/otorino20198403161.
[Traumatic perilymphatic fistula with the luxation of the stapes into vestibule].
[Article in Russian; Abstract available in Russian from the publisher]
Bannikov SA1, Boiko NV2, Pisarenko EA1, Kolesnikov VN2.
Author information
1
Regional Consultative-Diagnostic Center, Rostov-on-Don, Russia, 344000.
2
ENT department of Rostov State Medical University, Rostov-on-Don, Russia, 344022.
Abstract
A case of perilymphatic fistula with the luxation of the stapes into vestibule was described, which was caused by a direct damage of the eardrum (the patient cleaned the right ear with a cotton swab and received a strong blow to the arm). The moment of injury was characterized by severe pain, a significant hearing loss, the appearance of tympanophonia and vertigo. Clinical examination revealed the eardrum rupture. After perforation healing the hearing did not improve, a high degree of mixed sensorineural hearing loss remained with a bone-air interval of up to 50 dB throughout the tone scale. CT of the temporal bones showed a pneumolabirinth and a change in the malleus position, which made it possible to suggest the presence of a perilymphatic fistula with the luxation of the stapes. The extent of damage was confirmed by surgery. The stapes was removed and the perilymphatic fistula was closed.

KEYWORDS:
perilymphatic fistula; pneumolabirinth

PMID: 31486430 DOI: 10.17116/otorino20198403161
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Select item 31486429
6.
Vestn Otorinolaringol. 2019;84(3):56-60. doi: 10.17116/otorino20198403156.
[Clinical case for removal infralabyrinthine petrous bone cholesteatoma with preservation the facial nerve].
[Article in Russian; Abstract available in Russian from the publisher]
Anikin IA1, Khamgushkeeva NN1, Astashchenko SV1, Bokuchava TA2.
Author information
1
St.-Petersburg Research Institute of Ear, Throat, Nose and Speech, St.-Petersburg, Russia, 190013.
2
Murmansk Regional Clinical Hospital named P.A. Bayandin, Murmansk, Russia, 183035.
Abstract
The article presents the case report of infralabyrinthine petrous bone cholesteatoma. We have analyzed the preoperative examination of the patient for identification method of surgical treatment with preservation the facial nerve and reducing cholesteatoma risk, perioperative findings and the end result of surgical treatment.

KEYWORDS:
chronic otitis media; facial nerve; intraoperative facial nerve monitoring; petrous bone cholesteatoma

PMID: 31486429 DOI: 10.17116/otorino20198403156
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Select item 31486428
7.
Vestn Otorinolaringol. 2019;84(3):51-55. doi: 10.17116/otorino20198403151.
[External nasal valve. Method of reconstruction with its dysfunction].
[Article in Russian; Abstract available in Russian from the publisher]
Gilifanov EA1, Lepeyko BA2, Ardeeva LB1, Ivanets IV3, Tilik TV4, Klemeshova TP5, Prokhorenko AV6, Remizova VG7.
Author information
1
Federal State Budgetary Educational Institution of Higher Education 'Pacific State Medical University' of the Ministry of Healthcare of the Russian Federation, Vladivostok, Russia, 690002.
2
Territory State Budgetary Institution of Healthcare 'Vladivostok Clinical Hospital #1', Vladivostok, Russia, 690078.
3
Mc 'Health', Vladivostok, Russia, 690002.
4
Federal State Budgetary Educational Institution of Higher Education 'Military Medical Academy Im. S.M. Kirov', Russia, 690005.
5
Llc 'Sanmedservice', Bolshoy Kamen, Russia, 692800.
6
State Budgetary Health Care Institution 'Kamchatka Regional Center for Medical Prevention', Petropavlovsk-Kamchatsky, Russia, 683016.
7
Regional State Budgetary Institution of Health 'Nakhodka City Hospital', Nakhodka, Russia, 692921.
Abstract
The aim of this work is to improve the reconstruction techniques the external nasal valve, with its dysfunction caused by vertically located lateral legs of the lower lateral cartilage. There is shown a brief analysis of the anatomy of the external and internal nasal valve, methods of reconstruction with its dysfunction and surgical correction of this. The method of reconstruction of the external nasal valve is proposed, where we have used the isolation and removal of the vertically extending lateral legs lower lateral cartilage and expansion of the valve zone by an auto / allogeneic cartilaginous graft. The advantages and disadvantages of the proposed method are estimated.

KEYWORDS:
dysfunction of the nasal valve; external nasal valve; reconstruction of the external nasal valve

PMID: 31486428 DOI: 10.17116/otorino20198403151
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Select item 31486427
8.
Vestn Otorinolaringol. 2019;84(3):46-50. doi: 10.17116/otorino20198403146.
[Symptomatic approach to diagnosis and treatment of inflammatory diseases of the outer ear].
[Article in Russian; Abstract available in Russian from the publisher]
Pal'chun VT1, Gurov AV1, Yushkina MA1.
Author information
1
The Russian National Research Medical University named after N.I. Pirogov, Moscow, Russia, 117997; Sverzhevsky Research Clinical Institute of Otorhinolaryngology, Moscow, Russia, 117152.
Abstract
The article presents a modern approach to the diagnosis and treatment of inflammatory diseases of the outer ear. The authors consider the main predisposing factors that determine the development of external otitis: traumatic injury, water ingress, use of in-the-ear headphones, occupational hazards and others. The role of various microorganisms, including Pseudomonas aeruginosa, Staphylococcus aureus, bacteria of Enterobacteriaceae family and fungi of genera Aspergillus, Candida, Penicillium, Mucor in the genesis of inflammatory pathology of the outer ear is discussed. For the purpose of effective treatment of external otitis the authors suggest to use a local combined preparation Candibiotic, which contains antibacterial, fungicidal, hormonal and analgesic components that affect the main factors of pathogenesis of the disease.

KEYWORDS:
Candibiotic; external otitis; inflammation; local therapy

PMID: 31486427 DOI: 10.17116/otorino20198403146
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Select item 31486426
9.
Vestn Otorinolaringol. 2019;84(3):41-45. doi: 10.17116/otorino20198403141.
[Clinical and some biochemical features of rhinosinusitis of different etiology].
[Article in Russian; Abstract available in Russian from the publisher]
Ivanov MO1, Maksimenya MV1, Karavaeva TM1, Fefelova EV1, Egorova EV1, Tsybikov NN1.
Author information
1
Chita State Medical Academy, Ministry of Health of the Russian Federation, Chita, Russia, 672000.
Abstract
Identified pathogens, and studied the features of the clinical picture, the level of antioxidant activity, the number of TBA-active products, cytokines, chaperones proteins and antibodies against them in the serum of patients with fungal, viral, bacterial rhinosinusitis (RS) were studied. Most RS of viral nature are caused by rhinoviruses, in turn, the causative agent of bacterial RS, most often acts as a polyflora (S. epidermidis, S. aureus, Pseudomonas aeruginosa). In the group of fungal RS prevailed A. fumigatus. It is noted that a more severe clinical picture in patients bacterial RS; it was manifested by a prolonged course, more pronounced nasal congestion, smell impairment and frequent relapses of the disease. High levels of LPO and a decrease in serum antioxidant activity were established for all studied infectious RS with a maximum imbalance in the LPO-AOP system in fungal forms; shift of the cytokine profile towards pro-inflammatory factors (IL-1b, IL-2, IL-8, IL-6) was registered in bacterial and viral RS and towards the values of anti-inflammatory IL-4 - in fungal RS. The increased amount of chaperone proteins was seen in bacterial RS; high concentration of antibodies against them was noted in fungal and viral RS.

KEYWORDS:
antibodies; chaperone proteins; interleukins; lipid peroxidation; rhinosinusitis

PMID: 31486426 DOI: 10.17116/otorino20198403141
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Select item 31486425
10.
Vestn Otorinolaringol. 2019;84(3):37-40. doi: 10.17116/otorino20198403137.
[Features of the sinusitis course in pregnant women].
[Article in Russian; Abstract available in Russian from the publisher]
Karpishchenko SA1, Ryabova MA1, Shumilova NA1, Georgieva LV2, Nikitin KA3.
Author information
1
Department of Otorhinolaryngology, Pavlov First Saint Petersburg State Medical University, St.-Petersburg, Russia, 197022.
2
Department of Otorhinolaryngology, Pavlov First Saint Petersburg State Medical University, St.-Petersburg, Russia, 197022; Department of early diagnosis of allergic diseases in women of childbearing age of the clinic of the scientific clinical research center, Pavlov First Saint Petersburg State Medical University, St.-Petersburg, Russia, 197022.
3
Department of Otorhinolaryngology, St.-Petersburg, Russia, 197022.
Abstract
The purpose of the work was to study the sinusitis diagnostic and clinical features in pregnant women. The pregnant women group (27 human) with sinusitis from 816 pregnant women with nasal congestion and/or nasal discharge was analyzed. The examination included: taking anamnesis, ENT examining, clinical blood test. The frequency of sinusitis in pregnant women with complaints of nasal congestion and/or nasal discharge is 4.7%. The development of sinusitis was associated with inadequate treatment of chronic rhinitis during pregnancy in a third of cases. The course of sinusitis was characterized by the absence of intoxication and fever, in 78% of cases - by the absence of facial pain. In 74% of cases, the onset of the disease was erased. In pregnant women with sinusitis, in comparison with pregnant women with manifestations of chronic rhinitis, had a significant increase in ESR and a tendency to an increase of neutrophils. CONCLUSION: The development of sinusitis in pregnant women in a third of cases is due to the ineffective treatment of chronic rhinitis, and the erased clinical picture of the disease suggests the need for a thorough assessment of the anamnestic and clinical symptoms of the disease.

KEYWORDS:
pregnancy; rhinitis; sinusitis

PMID: 31486425 DOI: 10.17116/otorino20198403137
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Select item 31486424
11.
Vestn Otorinolaringol. 2019;84(3):32-36. doi: 10.17116/otorino20198403132.
[Combined application of modern endoscopic techniques in the detection of precancerous and malignant lesions of larynx].
[Article in Russian; Abstract available in Russian from the publisher]
Svistushkin VM1, Reshetov IV2, Chuchueva ND1, Saltykov BB3.
Author information
1
Department of ear, nose, throat diseases, Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russia, Moscow, Russia.
2
Department of oncology, plastic and reconstructive surgery and radiology, Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russia, Moscow, Russia.
3
Department of pathological anatomy, Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russia, Moscow, Russia.
Abstract
INTRODUCTION:
Early detection of malignant laryngeal tumors is crucial but still challenging. And 5-year survival rate depends on a stage of revealing. The aim of the study - assessment of the effectiveness of combined application of narrow band imaging and contact endoscopy in visualization of neoangiogenesis.

MATERIAL AND METHODS:
102 patients were included in this study. All the patients were evaluated by means of narrow band imaging and contact endoscopy.

RESULTS:
Combined application of narrow band imaging and contact endoscopy gained a high level of effectiveness: accuracy - 93.9%, sensitivity - 96%, specificity - 93.4%, positive predictive value - 94.3%, negative predictive value - 93.4%.

CONCLUSION:
Combined application of narrow band imaging and contact endoscopy may contribute to early detection of malignant laryngeal tumors.

KEYWORDS:
contact endoscopy; endoscopy; laryngeal cancer; narrow band imaging endoscopy

PMID: 31486424 DOI: 10.17116/otorino20198403132
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Select item 31486423
12.
Vestn Otorinolaringol. 2019;84(3):26-31. doi: 10.17116/otorino20198403126.
[Proinflammatory cytokine content in the saliva of children suffering from chronic tonsillitis].
[Article in Russian; Abstract available in Russian from the publisher]
Boiko NV1, Stagnieva IV1, Kim AS1, Simbirtsev AS2.
Author information
1
ENT Department of Rostov State Medical University, Rostov-on-Don, Russia, 344022.
2
State Research Institute of High Pure Biopreparations, St.-Petersburg, Russia, 197110.
Abstract
INTRODUCTION:
We have examined 92 children aged between 6 and 15, suffering from chronic tonsillitis (CT). Tumor necrosis factor (TNF-α) and interleukin 1β and 6 (IL-1β and IL-6) contents have been defined in saliva. The control set comprised 17 healthy children. Cytokine content was defined with the enzyme multiplied immunoassay sets (Vektor Best Ltd., Russia) by enzyme-linked immunosorbent assay. The statistic analysis and data processing were carried out with statistic analysis programs (version 3.2, R Foundation for Statistical Computing, Vienna, Austria).

RESULTS:
The content of cytokines TNF-α, IL-1, IL-6 in CT children's saliva was high against the healthy children, yet the statistically significant differences were only noted for IL-6. In the CT group the median value of this factor (12.5) was significantly higher than in the control set (6.72) (p=0.01 in Mann-Whitney assessment). IL-6 was chosen as the basic factor for the mathematic model; its combinations in the form of a multi-factor logistic regression were given consideration. From out of the three possible models there was just one that had all the coefficients statistically significantly different from zero (TNF-α - IL-6). It was chosen as the basic diagnostic model for chronic tonsillitis. The created model's sensitivity is 80.4%, while its specificity is 82.4%.

DISCUSSION:
The revealed IL-6 dominance in saliva at CT can be is attributable to permanent antigenic challenge characteristic of the toxic allergic CT since, as previously shown, there are living proliferating microorganisms in the palatal tonsil tissues and their blood- and lymph vessels at CT.

CONCLUSION:
The conducted ROC-analysis has demonstrated high sensitivity and specificity of the mathematical model, which enabled us to recommend determination of IL-6 in the saliva of the children suffering from CT as an additional diagnostic criterion.

KEYWORDS:
children; chronic tonsillitis; content of cytokines in saliva; diagnostics

PMID: 31486423 DOI: 10.17116/otorino20198403126
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Select item 31486422
13.
Vestn Otorinolaringol. 2019;84(3):22-25. doi: 10.17116/otorino20198403122.
[Retention cysts: a new approach to treatment].
[Article in Russian; Abstract available in Russian from the publisher]
Kryukov AI1, Turovsky AB2, Kolbanova IG2, Musayev KM2, Aleksanyan TA2, Luchsheva YV2.
Author information
1
Sverzhevsky Research Clinical Institute of Otorhinolaryngology, Moscow, Russia, 117152; Pirogov Russian National Research Medical University, Moscow, Russia, 117997.
2
Sverzhevsky Research Clinical Institute of Otorhinolaryngology, Moscow, Russia, 117152.
Abstract
In 2017-2018, the authors examined and operated on 35 patients aged 20 to 39 years (19 women, 16 men) with cystic maxillary sinusitis. The study included patients who were diagnosed with retention cyst of the maxillary sinus, located on the lower walls of the maxillary sinus and dealing with no more than 2/3 of the maxillary sinus volume, according to CT of the paranasal sinuses. The operation was performed using the following method: two punctures of the sinus were performed simultaneously in a typical place in the lower nasal passage - using a Kulikovsky needle and using a 2.8 mm trocar. The fiber of the Ho-laser was inserted into the Kulikovsky needle, and an endoscope was inserted into the trocar in parallel with the 0, 30 or 45°. Then, under the control of the endoscope, the fiber was inserted into the cyst and given a series of impulses before its 'explosion'. The parameters Ho:YAG-radiation had the following values: power - 14.4 W, pulse energy - 1.2 Jol, pulse frequency - 12.0 Hz. All patients were discharged from the hospital on the 2nd day. In the long-term period (up to 14 months), according to the endoscopic examination, an objective examination and CT of the paranasal sinuses showed no recurrence of the cyst in any patient, no pathological changes were recorded in the area of the lower nasal passage.

KEYWORDS:
laser surgery of maxillary sinus; maxillary sinus cyst; retention cyst

PMID: 31486422 DOI: 10.17116/otorino20198403122
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Select item 31486421
14.
Vestn Otorinolaringol. 2019;84(3):16-21. doi: 10.17116/otorino20198403116.
[Variants of bone tissue modification in chronic otitis media according to light and electron microscopy].
[Article in Russian; Abstract available in Russian from the publisher]
Dubinets ID1, Korkmazov MY1, Sinitsky AI1, Sychugov GV2, Tyukhay MV3.
Author information
1
Federal State Budgetary Educational Institution of Higher Education 'South Urals State Medical University' of the Ministry of Healthcare of the Russian Federation, Chelyabinsk, Russia, 454092.
2
Laboratory of Electron Microscopy GBUZ CHOPAB, Chelyabinsk, Russia, 454000.
3
South Ural State University, Chelyabinsk, Russia, 454021.
Abstract
PURPOSE:
Analysis of the results of surgical treatment of patients with chronic hepatitis C, depending on the characteristics of structural changes in the bone tissue of the middle ear.

PATIENTS AND METHODS:
Bone tissue of the retrotympanal cavities was obtained when performing various types of reconstructive sanitizing interventions: 123 samples for light microscopy and 35 samples in parallel for electron microscopy.

RESULTS:
The article presents the results of a retrospective analysis of the clinical features and surgical treatment of 177 patients with chronic suppurative otitis media. For histomorphological assessment, pathological processes of structural changes in the bone tissue of the middle ear were studied using acid-free microwave decalcification.

CONCLUSION:
The obtained data allowed to establish options for ultrastructural changes in the bone tissue of varying severity in chronic inflammation depending on the types of structure of the mastoid during the duration of the disease for more than 10 years.

KEYWORDS:
chronic purulent otitis media; light and electron microscopy; reconstructive sanitizing surgery; variants of bone structural changes

PMID: 31486421 DOI: 10.17116/otorino20198403116
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Select item 31486420
15.
Vestn Otorinolaringol. 2019;84(3):12-15. doi: 10.17116/otorino20198403112.
[Improving the methods of diagnosis and treatment of otitis media with effusion].
[Article in Russian; Abstract available in Russian from the publisher]
Vishnyakov VV1, Talalaev VN1, Atlashkin DN1.
Author information
1
Evdokimov Moscow State Medical Stomatological University, Russian Ministry of Health, Moscow, Russia, 127473.
Abstract
The study involved 172 patients with otitis media with effusion. All patients as a method of early diagnosis of otitis media with effusion conducted multislice computer tomography (MSCT). This made it possible to check the effectiveness of conservative treatment and timely perform surgical treatment, including sanitizing intervention on the middle ear with the erased clinical picture of acute mastoiditis, and to avoid complications. With the help of MSCT of the temporal bones with the dynamic observation of patients with high accuracy, you can confirm the full restoration of pneumatization of the middle ear cavities or identify possible recurrences of exudate accumulation. Patients who underwent surgery were randomly divided into 2 groups, depending on the duration of the laser myringotomy: on the 3rd day of hospital treatment (first group) or on the 7th day of hospital treatment (second group). Absence of otorrhea from the tympanic cavity and return of hearing in patients of the first group was significantly in a shorter period (p<0.05). CO2-laser myringotomy for patients with otitis media with effusion without positive dynamic by conservative therapy is most effectively in the early stages of the disease.

KEYWORDS:
CO2-laser; laser myringotomy; otitis media with effusion

PMID: 31486420 DOI: 10.17116/otorino20198403112
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Select item 31486419
16.
Vestn Otorinolaringol. 2019;84(3):5-11. doi: 10.17116/otorino2019840315.
[Prospects of endoscopic otosurgery in children].
[Article in Russian; Abstract available in Russian from the publisher]
Rusetsky YY1, Meitel IY1, Sotnikova LS1, Malyavina US1, Kalugina MS1.
Author information
1
National medical research center for children's health of the Ministry of health of Russia, Moscow, Russia, 119991.
Abstract
Active progress in otosurgery opens up new opportunities for minimally invasive surgeries and significantly improves the results of treatment, but a number of problems remain unsolved, including in children. Despite the general positive trend of using the endoscope in otosurgery, in pediatric practice the data are insufficient and extremely contradictory. Literary sources show that, with certain advantages, the existing techniques of endoscopic tympanoplasty are far from perfect and inferior in effectiveness to classical microscopic techniques, which also necessitates further research in this field.

KEYWORDS:
endoscopic ear surgery; endoscopic otosurgery; endoscopic tympanoplasty; otosurgery in children

PMID: 31486419 DOI: 10.17116/otorino2019840315
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