New Findings The effects of acute mental stress on the mechanisms regulating cerebral blood flow remain unclear. The major novel findings of this study were that: 1) high mental stress and hypercapnia had an interactive effect on mean middle cerebral artery blood velocity; 2) high mental stress altered the regulation of cerebral blood flow; 3) the increased cerebrovascular hypercapnic reactivity was not driven by changes in mean arterial pressure alone; and 4) this increased perfusion with mental...
Thu Aug 29, 2019 11:52
New Findings What is the central question of this study? Does immunosuppression restore the baroreflex control of renal sympathetic nerve activity (RSNA) in an animal model of kidney injury? What is the main finding and its importance? Tacrolimus, a calcineurin inhibitor, restored the high and low‐pressure baroreflex control of RSNA following cisplatin induced renal injury. Abstract Cisplatin administration causes depression of renal haemodynamic and excretory function and is associated...
Thu Aug 29, 2019 15:33
New Findings What is the central question of the study? We have previously shown that sinusoidal galvanic vestibular stimulation (sGVS) induces greater modulation of skin sympathetic nerve activity (SSNA), but not muscle sympathetic nerve activity (MSNA), in participants who report nausea during simulated motion, but the effects on skin blood flow and blood pressure are unknown. What is the main finding and its importance? Nausea was associated with a greater increase in skin blood flow,...
Thu Aug 29, 2019 15:34
Abstract Objectives Mesenchymal stem cell‐based therapy is a reliable treatment for periodontal tissue regeneration, while ideal regeneration rate is still a facing problem. In previous study, we found SFRP2 a promising gene in modulating mesenchymal stem cells potential. We further investigated its role on periodontal tissue regeneration. Methods We created periodontitis model in miniature pigs and locally injected with stem cells from apical papilla (SCAP). The periodontitis models were...
Fri Aug 30, 2019 16:09
Publication date: October 2019Source: Neoplasia, Volume 21, Issue 10Author(s): Marianne Samir Makboul Issac, Einas Yousef, Muhammad Ramzan Tahir, Louis A. GabouryAbstractBreast cancer is a heterogeneous disease comprising the estrogen receptor (ER)–positive luminal subtype which is subdivided into luminal A and luminal B and ER-negative breast cancer which includes the triple-negative subtype. This study has four aims: 1) to examine whether Minichromosome Maintenance (MCM)2, MCM4, and MCM6 can be...
Fri Aug 30, 2019 18:02
Nature, Published online: 30 August 2019; doi:10.1038/d41586-019-02590-9Gaia Donati and Julie Gould discuss some of the career issues faced by physicists today.
Fri Aug 30, 2019 03:00
Nature, Published online: 30 August 2019; doi:10.1038/d41586-019-02584-7A consortium of US universities aims to examine how best to help a vulnerable population that is affected by anxiety and depression.
Fri Aug 30, 2019 03:00
Fri Aug 30, 2019 03:00
Nature, Published online: 28 August 2019; doi:10.1038/d41586-019-02580-xMetal-rich bodies could be hiding beneath the glassy remnants of celestial smash-ups.
Wed Aug 28, 2019 03:00
Nature, Published online: 29 August 2019; doi:10.1038/d41586-019-02569-6More than 600 years’ worth of records from Burgundy reveal the nudge of climate change.
Thu Aug 29, 2019 03:00
Nature, Published online: 30 August 2019; doi:10.1038/d41586-019-02551-2International panel lays out an ambitious vision of exploring the planet through to 2050.
Fri Aug 30, 2019 03:00
Nature, Published online: 30 August 2019; doi:10.1038/d41586-019-02588-3The government has acted following concerns about China's influence on campuses.
Fri Aug 30, 2019 03:00
Nature, Published online: 30 August 2019; doi:10.1038/d41586-019-02574-9Isotopes that caused a radiation spike earlier this month probably came from an exploding nuclear-reactor core — but device’s application is still unknown.
Fri Aug 30, 2019 03:00
Nature, Published online: 30 August 2019; doi:10.1038/d41586-019-02607-3Assembling the right team of mentors can be a daunting task. Plus: half a million genomes confirm there’s no single ‘gay gene’, and advice for compiling Registered Reports.
Fri Aug 30, 2019 03:00
Nature, Published online: 30 August 2019; doi:10.1038/s41586-019-1543-2Constraints on global mean sea level during Pliocene warmth
Fri Aug 30, 2019 03:00
Nature, Published online: 30 August 2019; doi:10.1038/d41586-019-02595-4In the Nature PastCast series, we delve into the archives to tell the stories behind some of Nature’s biggest papers.
Fri Aug 30, 2019 03:00
Heterogeneity of microvascular blood flow leading to tissue hypoxia is a common finding in patients with septic shock. It may be related to suboptimal systemic perfusion pressure and lead to organ failure. Map...
Thu Aug 29, 2019 03:00
Objectives: Diabetes mellitus (DM) is associated with a variety of sensory complications. Very little attention has been given to auditory neuropathic complications in DM. The aim of this study was to determine whether type 1 DM (T1DM) affects neural coding of the rapid temporal fluctuations of sounds, and how any deficits may impact on behavioral performance. Design: Participants were 30 young normal-hearing T1DM patients, and 30 age-, sex-, and audiogram-matched healthy controls. Measurements...
Wed Aug 28, 2019 03:00
Objectives: Cochlear implants (CIs) restore speech perception in quiet but they also eliminate or distort many acoustic cues that are important for music enjoyment. Unfortunately, quantifying music enjoyment by CI users has been difficult because comparisons must rely on their recollection of music before they lost their hearing. Here, we aimed to assess music enjoyment in CI users using a readily interpretable reference based on acoustic hearing. The comparison was done by testing “single-sided...
Wed Aug 28, 2019 03:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b06757
Fri Aug 30, 2019 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b05531
Fri Aug 30, 2019 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b08813
Fri Aug 30, 2019 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b07236
Fri Aug 30, 2019 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b06998
Fri Aug 30, 2019 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b05769
Fri Aug 30, 2019 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b07695
Fri Aug 30, 2019 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b05910
Fri Aug 30, 2019 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b07397
Fri Aug 30, 2019 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b07576
Fri Aug 30, 2019 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b05993
Fri Aug 30, 2019 07:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου