Sexual selection may play a role in the evolution of lamprey pheromones.
Tue Sep 03, 2019 19:39
Researchers offer new insight into the evolution of the suction ability of remora fishes, showcasing a bioinspired suction disk that mimics, and can exceed, the fish's uncanny powers of adhesion.
Tue Sep 03, 2019 23:25
They may not have been seen for the past 50 and 110 years, but an international study into their extinction has provided answers to how the world lost New Zealand's South Island kokako and huia.
02:42
Asthma allergic disease is caused by airway chronic inflammation. Some intracellular signaling pathways, such as MAPK and STAT3-SOCS3, are involved in the control of airway inflammation in asthma. The flavonoid sakuranetin demonstrated an anti-inflammatory effect in different asthma models. Our aim was to clarify how sakuranetin treatment affects MAPK and STAT3-SOCS3 pathways in a murine experimental asthma model. Mice were submitted to an asthma ovalbumin-induction protocol and were treated with...
Tue Sep 03, 2019 11:05
Infection is a common cause of hospitalization and mortality in patients with systemic lupus erythematosus (SLE). How the underlying immune dysfunctions affect the antimicrobial immunity remains largely unknown. In the present study, employing the pulmonary infection model, we determined the antimicrobial defence of lupus-prone mice. After infecting with opportunistic bacterium Haemophilus influenzae (Hi), lupus-prone mice (B6/lpr) exhibited inefficient bacterial elimination and recovered slowly....
Tue Sep 03, 2019 11:05
Atherosclerosis (AS) is a chronic inflammatory disease, and macrophages play a key role in all phases of AS. Recent studies have shown that miR-221 is a biomarker for AS and stroke; however, the role and mechanism of miR-221 in AS are unclear. Herein, we found that miR-221 and NCoR levels were decreased in ox-LDL-treated THP-1-derived macrophages. In contrast, DNMT3b, IL-6, and TNF-α expression levels were increased under these conditions. Upregulation of miR-221 or NCoR could partially inhibit ox-LDL-induced...
Tue Sep 03, 2019 11:05
Hoveniae semen seu fructus (HSF, fruit and seed of Hovenia dulcis Thunb) is an important traditional herbal medicine and food supplement in East Asia for the treatment of liver diseases, alcohol poisoning, obesity, allergy, and cancer. HSF has also been reported to have anti-inflammatory activity, but the cellular mechanism of action is not fully understood. We assessed the anti-inflammatory properties of an HSF ethanol (HSFE) extract and explored its precise mechanism. The ability of HSFE to suppress...
05:05
Abstract Objective Haptoglobin (Hp) is an acute‐phase protein secreted by the liver; its concentration increases rapidly during infection, inflammation, and tumor formation. It has been reported that the level of Hp α alleles is altered in the serum of patients with head and neck squamous cell carcinoma (HNSCC), and the cellular level of Hp is strongly associated with the recurrence rate of HNSCC in patients. In present study, the regulated mechanism of Hp expression was explored. Materials...
Tue Sep 03, 2019 11:28
Abstract Orofacial clefts are facial malformations caused by the improper development of the lips and palate. Many genetic and epigenetic molecules have been involved in the mechanisms of orofacial clefts, one of which are miRNAs. This systematic review aimed to identify miRNAs associated to non‐syndromic orofacial clefts in humans. After applying a series of criteria, four studies were selected for analysis. In total, one hundred miRNAs were observed in the literature, of which 57 were reported...
Tue Sep 03, 2019 20:43
Abstract Objectives To investigate the appearance of visible dentate nucleus (DN) T1-hyperintensity and quantify changes in DN/pons (DN/P) signal intensity (SI) ratio in MS patients after the exclusive administration of macrocyclic GBCAs. Materials and methods One hundred forty-nine patients with confirmed MS were evaluated. Patients received...
03:00
Abstract Duplications in the 22q11.2 region can cause 22q11.2 duplication syndrome and encompass a variety of phenotypes including developmental delays, facial abnormalities, cardiovascular defects, central nervous system delays, and other congenital abnormalities. However, the contribution of these contiguous duplicated regions to the clinical phenotypes has not been fully elucidated. In this study, we identified nine patients carrying different 22q11.2 microduplications detected by chromosomal...
Tue Sep 03, 2019 17:44
Surgical Infections, Ahead of Print.
Fri Aug 30, 2019 10:00
Tissue Engineering Part A, Ahead of Print.
Tue Sep 03, 2019 10:00
Tissue Engineering Part A, Ahead of Print.
Tue Sep 03, 2019 10:00
Tissue Engineering Part A, Ahead of Print.
Tue Sep 03, 2019 10:00
Tissue Engineering Part A, Ahead of Print.
Tue Sep 03, 2019 10:00
Tissue Engineering Part A, Ahead of Print.
Tue Sep 03, 2019 10:00
Tissue Engineering Part A, Ahead of Print.
Tue Sep 03, 2019 10:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου