Tue Sep 03, 2019 03:00
Mucosal Immunology, Published online: 03 September 2019; doi:10.1038/s41385-019-0200-2Intestinal proteomic analysis of a novel non-human primate model of experimental colitis reveals signatures of mitochondrial and metabolic dysfunction
Tue Sep 03, 2019 03:00
Mucosal Immunology, Published online: 03 September 2019; doi:10.1038/s41385-019-0198-5Small heat shock protein CRYAB inhibits intestinal mucosal inflammatory responses and protects barrier integrity through suppressing IKKβ activity
Tue Sep 03, 2019 03:00
Publication date: Available online 2 September 2019Source: Revue des Maladies RespiratoiresAuthor(s):
Tue Sep 03, 2019 17:05
Abstract Background Guidelines recommend nephron sparing surgery where possible for patients with T1 renal tumours. The trends of nephron sparing surgery outside the USA are limited, particularly since the introduction of robotic‐assisted partial nephrectomy (RAPN). The aim of this study was to describe contemporary surgical management patterns of renal tumours in Australia according to Medicare claims data. Methods Claims data according to the Medicare Benefits Schedule on surgical management...
Mon Sep 02, 2019 21:46
In the largest Australian series of robotic‐assisted radical cystectomy, initial short‐term experience shows technical improvements along a learning curve and favourable perioperative and survival outcomes compared to open and robotic radical cystectomy series. Abstract Background This study aimed to describe perioperative, oncological and learning curve outcomes for robotic‐assisted radical cystectomy (RARC) across the first 100 cases performed by an Australian high‐volume, fellowship‐trained...
Mon Sep 02, 2019 21:46
Mon Sep 02, 2019 21:48
A patent measurement technique has been designed to assess femoral rotation deformation. The aim of this study was to investigate and assess its possibility and reliability. Abstract Background A novel measurement technique has been designed to assess femoral rotation deformation. The purpose of this study was to evaluate smartphone‐aided measurement, including measurement software, intra‐observer differences and the occurrence frequency of the unacceptable outliers. Methods Five positions...
Mon Sep 02, 2019 21:48
Background: The rat orthotopic lung transplant model is not widely used yet because of the complexity of the procedure, in particular, venous anastomosis. Here, we performed a rat orthotopic lung transplantation using either the suture (ST) or cuff (CT) method for vein anastomosis. Objectives: To compare the vein ST and CT techniques in terms of operative time, success, recipient survival, and early histological outcomes was the objective of this study. Methods: A total of 24 left lung transplants...
Tue Sep 03, 2019 16:50
Background: Short-term kidney graft dysfunction is correlated with complications and it is associated with a decreased long-term survival; therefore, a scoring system to predict short-term renal transplant outcomes is warranted. Aim: The aim of this study is to quantify the impression of the organ procurement surgeon in correlation with the following kidney transplant outcomes: immediate graft function (IGF), delayed graft function (DGF), and primary nonfunction (PNF). Results are compared to factors...
Tue Sep 03, 2019 16:51
New England Journal of Medicine, Ahead of Print.
Tue Sep 03, 2019 05:40
Publication date: Available online 2 September 2019Source: Revista Española de Medicina Nuclear e Imagen MolecularAuthor(s): E. Noriega-Álvarez, L. Domínguez Gadea, M.P. Orduña Diez, V. Peiró Valgañón, S. Sanz Viedma, R. García JiménezResumenLas enfermedades inflamatorias e infecciosas osteoarticulares pueden tener graves consecuencias para el paciente si no se diagnostican a tiempo. En las últimas décadas, diferentes modalidades de la Medicina Nuclear han permitido estudiar la fisiopatología de...
Tue Sep 03, 2019 19:09
Last week, Sonavex, a Baltimore-based medical device company, announced receipt of a $3M Phase IIB Small Business Innovation Research (SBIR) grant for prospective clinical studies and ongoing research and development of its EchoMark and EchoSure devices. This grant funding from the National Institutes of Health (NIH) will specifically allow Sonavex to validate its technology’s application to arteriovenous (AV) fistula maturation and viability for patients with end-stage renal disease (ESRD)....
Tue Sep 03, 2019 16:49
The blood-brain barrier is nearly impenetrable to most drugs and contrast agents, making it difficult to diagnose and treat diseases afflicting the brain. Researchers at the Max Planck Institute for Polymer Research have now developed a way of using nanodiamonds coated with a biopolymer to penetrate through the blood-brain barrier and deliver therapies, as well as create the possibility for a novel form of brain imaging. Nanodiamonds, being nothing but carbon, are quite biocompatible, but...
Tue Sep 03, 2019 18:42
Viruses are so small that to be able to detect them using light you need instruments that work on the nanoscale. Sensors so perfect are very hard to make, as most manufacturing processes disrupt nanoscale structures. Now, a team at Purdue University has developed a way to combine 3D plasmonic nanoarrays, special light manipulation devices, with peelable films that can be applied to just about anything. They were then able to successfully combine the new stickers with conventional imaging systems...
Tue Sep 03, 2019 19:39
Most readers of this journal would recognise that occupational health (OH) research is valuable. The Society of Occupational Medicine (SOM), a UK-based organisation for healthcare professionals working in or with an interest in OH, recently released a report where the objective was to assess the value of OH research.1 To do this, they undertook a scoping review of economic evaluations of OH interventions (one aspect of OH research) and conducted a series of nine interviews with academic experts,...
Tue Sep 03, 2019 19:00
In May 2019, WHO has stated that burn-out should be considered as a disease in the new version of the International Classification of Diseases (ICD-11). This information was widely disseminated in the news media. However, a few hours later, the international organisation stepped back. All this confusion brings us to that question: what exactly is burn-out? Moreover, should it be considered a disease or not?Freudenberger defined burn-out as ‘a state of fatigue or frustration brought about devotion...
Tue Sep 03, 2019 19:00
Abstract The Fairfield Foundation is using new technology to record and recreate archaeology at Fairfield Plantation. Using drone-based photogrammetry, Autodesk 3-D modeling software, and a MakerBot 3-D printer, the organization is developing three-dimensional models of every stratigraphic layer excavated, then printing replicas of each layer that connect seamlessly. This interactive model of the site is ideal for teaching students and the public about archaeology while engaging...
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Nature Communications, Published online: 03 September 2019; doi:10.1038/s41467-019-11894-3Pituitary POMC secreting cells achieve high hormone expression levels after birth but the mechanism for this regulation is unclear. Here, the authors show that this process is driven cell autonomously by the differentiation factor Tpit that activates the bZIP transcription factors Creb3l2 and XBP1 to enhance translation and secretory capacities.
Tue Sep 03, 2019 03:00
Nature Communications, Published online: 03 September 2019; doi:10.1038/s41467-019-11964-6Materials exhibiting a Berry curvature (BC) show potential for optoelectronics, but, finite BC dipoles have so far only been shown in small-gap materials. Here in semiconducting tin telluride monolayers a ferroelectrically driven BC dipole is shown to be used to control charge and spin photocurrents.
Tue Sep 03, 2019 03:00
Nature Communications, Published online: 03 September 2019; doi:10.1038/s41467-019-11771-zHere, Llewellyn and colleagues present evidence of meiotic sex in Trypanosoma cruzi, the causative agent of Chagas disease. These findings have implications for the epidemiology of the disease in endemic regions and challenge existing ideas that the parasites are strictly clonal.
Tue Sep 03, 2019 03:00
Nature Communications, Published online: 03 September 2019; doi:10.1038/s41467-019-11851-0The nature of the signals that propagate through feedforward networks is not well understood. Here, the authors combine microfabrication, multilayer cortical cultures, and optogenetic stimulation to show that NMDA-mediated synaptic current generates a sustained phase of activity that propagates firing rate signals.
Tue Sep 03, 2019 03:00
Nature Communications, Published online: 03 September 2019; doi:10.1038/s41467-019-11822-5Linear controllability theories have stimulated research on control of complex networks. Here the authors investigate the concordance between linear and nonlinear approaches in ranking the importance of nodes in nonlinear networks, and conclude that linear controllability may not be applicable.
Tue Sep 03, 2019 03:00
Nature Communications, Published online: 03 September 2019; doi:10.1038/s41467-019-11938-8Gamma oscillations have been proposed to underlie many cognitive and memory processes, but it has proven difficult to directly test this by manipulating them. Here, in rats, the authors show that manipulation of gamma oscillations in the amygdala affects memory consolidation.
Tue Sep 03, 2019 03:00
Nature Communications, Published online: 03 September 2019; doi:10.1038/s41467-019-12106-8Author Correction: Fcmr regulates mononuclear phagocyte control of anti-tumor immunity
Tue Sep 03, 2019 03:00
Nature Communications, Published online: 03 September 2019; doi:10.1038/s41467-019-11927-xPublisher Correction: Gallium arsenide solar cells grown at rates exceeding 300 µm h−1 by hydride vapor phase epitaxy
Tue Sep 03, 2019 03:00
Tue Sep 03, 2019 03:00
Nature Communications, Published online: 03 September 2019; doi:10.1038/s41467-019-11691-yFemales tend to perform poorer than males on math and science tests, but better on verbal reading tests. Here, by analysing performance during a cognitive test, the authors provide evidence that females are better able to sustain their performance during a test across all of these topics.
Tue Sep 03, 2019 03:00
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