BMP-3 Promotes Matrix Production in Co-cultured Stem Cells and Disc Cells from Low Back Pain Patients

Tissue Engineering Part A, Ahead of Print.

Tissue Engineering Part A - Table of Contents

Thu Oct 31, 2019 09:00

Identification of driver genes regulating immune cell infiltration in cervical cancer by multiple omics integration

Publication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Yanqi Wen, Silin Zhang, Jing Yang, Duanying GuoAbstractCervical cancer (CC) is one of the most common cancers in women. However, copy number alteration (CNA)-driven dysregulated genes and their functions in CC are still rarely investigated. In the present study, we conducted integrative analysis of CNA and gene expression data from The Cancer Genome Atlas (TCGA) cervical cancer to identify dysregulated...

Biomedicine & Pharmacotherapy

Thu Oct 31, 2019 23:26

Pharmacoepidemiology

Publication date: Available online 31 October 2019Source: Clinical TherapeuticsAuthor(s): Richard I. Shader

ScienceDirect Publication: Clinical Therapeutics

Thu Oct 31, 2019 16:06

Protective effects of a neurokinin 1 receptor antagonist on airway epithelial mitochondria dysfunction in asthmatic mice via Nrf2/HO-1 activation

Publication date: December 2019Source: International Immunopharmacology, Volume 77Author(s): Zhijia Wang, Miao Li, Qianlan Zhou, Yunxiao Shang

ScienceDirect Publication: International Immunopharmacology

Thu Oct 31, 2019 14:49

Evaluation of the prognostic role of platelet-lymphocyte ratio in cancer patients treated with immune checkpoint inhibitors: A systematic review and meta-analysis

Publication date: December 2019Source: International Immunopharmacology, Volume 77Author(s): Huilin Xu, Anbing He, Aihua Liu, WenXian Tong, Dedong CaoAbstractObjectiveWhether platelet-lymphocyte ratio (PLR) is a prognostic factor for cancer patients treated with immunotherapy is under debate. In this study, we aimed to evaluate the relationship between PLR and survival of cancer patients treated with immune checkpoint inhibitors (ICIs).MethodsA systematical search was performed in databases including...

ScienceDirect Publication: International Immunopharmacology

Thu Oct 31, 2019 14:49

Ethyl pyruvate enhances spontaneous remyelination by targeting microglia phagocytosis

Publication date: December 2019Source: International Immunopharmacology, Volume 77Author(s): Yan He, Jun An, Jun-Jun Yin, Ruo-Xuan Sui, Qiang Miao, Zhi-Bin Ding, Qing-Xian Han, Qing Wang, Cun-Gen Ma, Bao-Guo XiaoAbstractEthyl pyruvate (EP), a simple derivative of the endogenous energy substrate pyruvate, provides strong anti-inflammatory and anti-oxidative properties. but its role in remyelination has not been explored. In this study, EP efficiently improved the behavioural performance and histological...

ScienceDirect Publication: International Immunopharmacology

Thu Oct 31, 2019 14:49

Tear and serum MMP-9 and serum TIMPs levels in the severe sulfur mustard eye injured exposed patients

Publication date: December 2019Source: International Immunopharmacology, Volume 77Author(s): Hassan Ghasemi, Roya Yaraee, Soghrat Faghihzadeh, Mohammad Ghassemi-Broumand, Mahmoud Mahmoudi, Mahmoud Babaei, Mostafa Naderi, Maliheh Safavi, Zeinab Ghazanfari, Maryam Rastin, Shahrzad Zamani, Nafiseh Tabasi, Elham Faghihzadeh, Reza Gharebaghi, Zuhair Mohammad Hassan, Ensie sadat Mirsharif, Tooba GhazanfariAbstractIntroductionSulfur mustard (SM) intoxication produces local and systemic changes in the human...

ScienceDirect Publication: International Immunopharmacology

Thu Oct 31, 2019 14:49

Ampelopsin attenuates carbon tetrachloride-induced mouse liver fibrosis and hepatic stellate cell activation associated with the SIRT1/TGF-β1/Smad3 and autophagy pathway

Publication date: December 2019Source: International Immunopharmacology, Volume 77Author(s): Jie-Qiong Ma, Yun-Zhi Sun, Qing-Lei Ming, Zhi-Kai Tian, Hui-Xin Yang, Chen-Min LiuAbstractAmpelopsin (Amp), a natural flavonoid found in the vine tea of Ampelopsis grossedentata, exhibited anti-cancer, anti-oxidant, anti-inflammatory, anti-apoptosis and hepatoprotective properties. The current study instigates the protective effect of Amp on carbon tetrachloride (CCl4)-induced hepatic fibrosis and explores...

ScienceDirect Publication: International Immunopharmacology

Thu Oct 31, 2019 14:49

Trichostatin A modulates the macrophage phenotype by enhancing autophagy to reduce inflammation during polymicrobial sepsis

Publication date: Available online 31 October 2019Source: International ImmunopharmacologyAuthor(s): Shu-Nan Cui, Zhao-Yuan Chen, Xiao-Bo Yang, Lin Chen, Yi-Yi Yang, Shang-Wen Pan, Ya-Xin Wang, Ji-Qian Xu, Ting Zhou, Hai-Rong Xiao, Lu Qin, Shi-Ying Yuan, You ShangAbstractSepsis is a syndrome of life-threatening organ dysfunction caused by dysregulated host responses to infection. Macrophage polarization is a key process involved in the pathogenesis of sepsis. Recent evidence has demonstrated that...

ScienceDirect Publication: International Immunopharmacology

Thu Oct 31, 2019 14:49

Lymphocyte count and lymphocyte-to-white blood cells ratio as indicators of survival in specific cancer subtypes

Publication date: Available online 31 October 2019Source: International ImmunopharmacologyAuthor(s): M. Cefalì, A. Efstathopoulou, S. De Dosso, P. Saletti

ScienceDirect Publication: International Immunopharmacology

Thu Oct 31, 2019 14:49