Publication date: Available online 4 November 2019Source: World NeurosurgeryAuthor(s): Salim Şentürk, Ülkün Ünlü Ünsal
Sat Nov 09, 2019 19:19
Publication date: Available online 4 November 2019Source: World NeurosurgeryAuthor(s): Elliot Pressman, David Penn, Nirav Patel
Sat Nov 09, 2019 19:19
Publication date: Available online 4 November 2019Source: World NeurosurgeryAuthor(s): Hoon Kim, Kwang Wook JoAbstractObjectiveThe purpose of this study was to assess the natural course of contrast-induced nephropathy (CIN) and to determine the predictive abilities of preprocedural high-sensitivity C-reactive protein (hs-CRP) and urine neutrophil gelatinase-associated lipocalin (uNGAL) for CIN after neurointervention procedures.MethodsWe prospectively enrolled 176 patients who underwent an elective...
Sat Nov 09, 2019 19:19
Publication date: Available online 4 November 2019Source: World NeurosurgeryAuthor(s): Li Mei, Mu Fengqun, Han Qian, Su Dongpo, Guo Zhenzhong, Chen TongAbstractObjectiveTo explore whether endoscopy surgery (ES) and external ventricular drainage (EVD) combined with intraventricular fibrinolytic (IVF) are superior to EVD-alone in patients with intraventricular hemorrhage (IVH), and to determine which procedure is more suitable in such patients.MethodsWe searched the following databases: PubMed, Medline,...
Sat Nov 09, 2019 19:19
Publication date: Available online 4 November 2019Source: World NeurosurgeryAuthor(s): Sun Geon Yoon, Min Su Kim, Soon Chan Kwon, In Uk Lyo, Hong Bo Sim
Sat Nov 09, 2019 19:19
Publication date: Available online 4 November 2019Source: World NeurosurgeryAuthor(s): Regina Yun, Daniel M. Sciubba, John Lewin, Michael B. Streiff, Elliott R. Haut, Brandyn D. Lau, Kenneth M. Shermock, Peggy S. Kraus, Victor O. Popoola, Stacy Elder DalpoasAbstractBackgroundVenous thromboembolism (VTE) is a cause of considerable morbidity and mortality in hospitalized patients. An evidence-based algorithm was developed and implemented at our institution to guide perioperative VTE prophylaxis management.ObjectiveWe...
Sat Nov 09, 2019 19:19
Publication date: Available online 4 November 2019Source: World NeurosurgeryAuthor(s): Antonio Montalvo Afonso, Juan Vicente Darriba Alles, Ángela Moreno Gutiérrez, Lain Hermes González Quarante, Roberto García Leal, Juan Adan Guzmán de Villoria Lebiedziejewski, PhD Emma Sola VendrellAbstractBackgroundGranular cell astrocytoma (GCA) is a rare and aggressive subtype of astrocytoma histopathologically well-defined in the literature. It is formed by polygonal cells with granular cytoplasm mixed with...
Sat Nov 09, 2019 19:19
Publication date: Available online 4 November 2019Source: World NeurosurgeryAuthor(s): Amos O. Adeleye
Sat Nov 09, 2019 19:19
To compare irradiation dose to the second and third portions of duodenum (Duo2 and Duo3) with a new refined and old delineation method of para-aortic region for patients with locally advanced cervical cancer (...
Fri Nov 08, 2019 02:00
Inspired by the easy cleavability of P–N bonds, a facile protocol has been developed to access 1,2,3‐triphospholanium triflates and triphosphanium triflate salts. [LCRP((PhP)2C2H4)][OTf] (4a,b[OTf]) and [LCiPrP(PPh2)2][OTf] (5b[OTf]) can be prepared from the reaction of imidazoliumyl‐substituted dipyrazolylphosphane triflate salts [LCR–P(pyr)2][OTf] (3a,b[OTf]; a: R = Me, b = iPr; LCR = 1,3‐dialkyl‐4,5‐dimethyl‐imidazol‐2‐yl; pyr = 3,5‐dimethyl‐pyrazol‐1‐yl) with the secondary phosphanes PhP(H)C2H4P(H)Ph)...
Sat Nov 09, 2019 19:08
Thermally activated delayed fluorescence (TADF) polymers are of great interest due to their compatibility with the low‐cost wet methods (spin‐coating, inkjet printing etc.). However, they have received less attention compared with small molecules. Based on a “TADF + Linker” strategy, here we demonstrate the successful construction of conjugated polymers allowing highly efficient delayed fluorescence. In this case, a small molecular TADF block is simply bonded together to form the polymers by a methyl‐substituted...
Sat Nov 09, 2019 19:08
Pinching molecules via chemical strain suggests intuitive consequences, such as compression at the pinched site, and clothespin‐like opening of other parts of the structure. If this opening affects two spin centers, it should result in reduced communication between them. We show that for naphthalene‐bridged biscobaltocenes with competing through‐space and through‐bond pathways, the consequences of pinching are far less intuitive: despite the known dominance of through‐space interactions, the bridge...
Sat Nov 09, 2019 17:27
We have developed an easy method for the double functionalization of graphene oxide (GO) using benzoquinone in mild alkaline conditions. Two functional groups were covalently linked onto GO following two separate steps: the first group was attached by an epoxide ring opening reaction while the second moiety, bearing an amine function, was covalently conjugated through a Michael addition on benzoquinone covalently bound in turn to GO. The double functionalized GO was characterized by different techniques...
Sat Nov 09, 2019 15:10
Three new post‐synthetic modification reactions, namely amidation, esterification, and thioesterification, were demonstrated on a novel highly crystalline two‐dimensional covalent organic framework (COF), COF‐616, bearing pre‐installed carboxyl groups. The strategy can be used to introduce a large variety of functional groups into COFs and the modifications can be carried out under mild reaction conditions, with high yields, and an easy work‐up protocol. As a proof of concept, various sulfur‐ and...
Fri Nov 08, 2019 17:10
Publication date: Available online 9 November 2019Source: NeuroImageAuthor(s): Ramina Adam, Kevin Johnston, Ravi S. Menon, Stefan EverlingAbstractVisual extinction has been characterized by the failure to respond to a visual stimulus in the contralesional hemifield when presented simultaneously with an ipsilesional stimulus (Corbetta and Shulman, 2011). Unilateral damage to the macaque frontoparietal cortex commonly leads to deficits in contralesional target selection that resemble visual extinction....
Sat Nov 09, 2019 19:07
Publication date: Available online 9 November 2019Source: NeuroImageAuthor(s): Neda Kaboodvand, Behzad Iravani, Peter FranssonAbstractAttention deficit hyperactivity disorder (ADHD) is characterized by high distractibility and impaired executive functions. Notably, there is mounting evidence suggesting that ADHD could be regarded as a default mode network (DMN) disorder. In particular, failure in regulating the dynamics of activity and interactions of the DMN and cognitive control networks have been...
Sat Nov 09, 2019 19:07
Publication date: Available online 9 November 2019Source: NeuroImageAuthor(s): Heiko Backes
Sat Nov 09, 2019 19:07
Publication date: Available online 9 November 2019Source: NeuroImageAuthor(s): Stefan M. Spann, Xingfeng Shao, Danny JJ. Wang, Christoph S. Aigner, Matthias Schloegl, Kristian Bredies, Rudolf StollbergerAbstractFor ASL perfusion imaging in clinical settings the current guidelines recommends pseudo-continuous arterial spin labeling with segmented 3D readout. This combination achieves the best signal to noise ratio with reasonable resolution but is prone to motion artifacts due to the segmented readout....
Sat Nov 09, 2019 19:07
Publication date: Available online 9 November 2019Source: NeuroImageAuthor(s): Anne Margarette S. Maallo, Erez Freud, Tina Tong Liu, Christina Patterson, Marlene BehrmannAbstractChildren with unilateral resections of ventral occipito-temporal cortex (VOTC) typically do not evince visual perceptual impairments, even when relatively large swathes of VOTC are resected. In search of possible explanations for this behavioral competence, we evaluated white matter microstructure and connectivity in eight...
Sat Nov 09, 2019 19:07
Publication date: Available online 8 November 2019Source: NeuroImageAuthor(s): Lorena Santamaria, Valdas Noreika, Stanimira Georgieva, Kaili Clackson, Sam Wass, Victoria LeongAbstractEmotional communication between parents and children is crucial during early life, yet little is known about its neural underpinnings. Here, we adopt a dual connectivity approach to assess how positive and negative emotions modulate the interpersonal neural network between infants and their mothers during naturalistic...
Sat Nov 09, 2019 19:07
Publication date: Available online 8 November 2019Source: NeuroImageAuthor(s): William T. Clarke, Olivier Mougin, Ian D. Driver, Catarina Rua, Andrew T. Morgan, Michael Asghar, Stuart Clare, Susan Francis, Richard G. Wise, Christopher T. Rodgers, Adrian Carpenter, Keith Muir, Richard BowtellAbstractIncreasing numbers of 7 T (7 T) magnetic resonance imaging (MRI) scanners are in research and clinical use. 7 T MRI can increase the scanning speed, spatial resolution and contrast-to-noise-ratio of many...
Sat Nov 09, 2019 19:07
Publication date: Available online 8 November 2019Source: NeuroImageAuthor(s): Julian Q. Kosciessa, Thomas H. Grandy, Douglas D. Garrett, Markus Werkle-BergnerAbstractThe average power of rhythmic neural responses as captured by MEG/EEG/LFP recordings is a prevalent index of human brain function. Increasing evidence questions the utility of trial-/group averaged power estimates however, as seemingly sustained activity patterns may be brought about by time-varying transient signals in each single...
Sat Nov 09, 2019 19:07
Publication date: Available online 8 November 2019Source: Acta HistochemicaAuthor(s): A.K. Grzegorzewska, A. Hrabia, K. Kowalik, D. Katarzyńska-Banasik, A. Kozubek, A. SechmanAbstractThis study aimed to examine the mRNA expression, activity, and immunolocalisation of apoptosis/proliferation regulating factors following in vitro exposure of the stroma, white (WFs), and yellowish (YFs) follicles of the chicken ovary to 4-nitrophenol (PNP) or 3-methyl-4-nitrophenol (PNMC). PNMC increased the mRNA expression...
Sat Nov 09, 2019 19:01
Publication date: Available online 9 November 2019Source: Gait & PostureAuthor(s): Eran Gazit, Aron S. Buchman, Robert Dawe, Thomas A. Curran, Anat Mirelman, Nir Giladi, Jeffrey M. HausdorffAbstractBackgroundWalking is a volitional behavior that requires planning and initiation before a step is observed. Following a signal to begin walking, studies of gait initiation in specialized labs have identified three phases that occur during the transition from a standing position via anticipatory postural...
Sat Nov 09, 2019 18:57
Publication date: Available online 8 November 2019Source: Gait & PostureAuthor(s): I Arpan, PC Fino, B Fling, F Horak
Sat Nov 09, 2019 18:57
Publication date: Available online 8 November 2019Source: Gait & PostureAuthor(s): Pouyan Mehryar, Mohammad S. Shourijeh, Tahmineh Rezaeian, Amin R. Khandan, Neil Messenger, Rory O’Connor, Farzam Farahmand, Abbas Dehghani-SanijAbstractBackgroundLower limb amputation is a major public health issue globally, and its prevalence is increasing significantly around the world. Previous studies on lower limb amputees showed analogous complexity implemented by the neurological system which does not depend...
Sat Nov 09, 2019 18:57
Publication date: Available online 9 November 2019Source: Clinical NeurophysiologyAuthor(s): E. Elena Pavlidis, Rhodri O. Lloyd, Vicki Livingstone, John M. O'Toole, Peter M. Filan, Francesco Pisani, Geraldine B. BoylanAbstractObjectiveTo develop a standardised scheme for assessing normal and abnormal electroencephalography (EEG) features of preterm infants. To assess the interobserver agreement of this assessment scheme.MethodsWe created a standardised EEG assessment scheme for 6 different post-menstrual...
Sat Nov 09, 2019 18:55
Publication date: Available online 9 November 2019Source: Clinical NeurophysiologyAuthor(s): Luca Gentile, Daniele Coraci, Costanza Pazzaglia, Filippo Del Tedesco, Carmen Erra, Domenica Le Pera, Luca PaduaAbstractObjectivesTo increase the specificity of motor unit potential (MUPs) detection by using ultrasound guided electromyography (USG-EMG) in patients with muscle plegia due to traumatic nerve lesions.MethodsForty-six patients with recent nerve trauma underwent baseline standard EMG (ST-EMG) evaluation...
Sat Nov 09, 2019 18:55
Publication date: Available online 9 November 2019Source: Clinical NeurophysiologyAuthor(s): Mamede de Carvalho, Michael Swash
Sat Nov 09, 2019 18:55
Publication date: Available online 9 November 2019Source: Clinical NeurophysiologyAuthor(s): Carlo Alberto Tassinari
Sat Nov 09, 2019 18:55
Abstract Next‐generation sequencing has revealed mutations in several bone‐related lesions and was recently used to uncover the genetic basis of giant cell lesions of the jaws (GCLJ). Consistent with their benign nature, GCLJ show a low tumor mutation burden. They also harbor somatic, heterozygous, mutually exclusive mutations in TRPV4, KRAS, or FGFR1. These signature mutations occur only in a subset of lesional cells, suggesting the existence of a ‘landscaping effect’, with mutant cells inducing...
Sat Nov 09, 2019 18:09
Several daily living activities require people to coordinate the motion and the force produced by both arms, using their position sense and sense of effort. However, to date, the interaction in bimanual tasks ...
Fri Nov 08, 2019 02:00
Publication date: Available online 9 November 2019Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Sabine A. Egeler, Anne Huang, Anna R. Johnson, Ahmed Ibrahim, Alexandra Bucknor, Abbas Peymani, Marc A.M. Mureau, Samuel J. LinAbstractIntroductionThe current literature is limited with regards to trends for inpatient head and neck skin cancer reconstruction. Rather, studies have focused primarily on patients treated on an outpatient basis. To gain a better understanding...
Sat Nov 09, 2019 18:39
Publication date: Available online 8 November 2019Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Mustafa Akyurek, Samandar Dowlatshahi, Robert M. QuinlanSummaryBackgroundLatissimus flap with prosthetic breast reconstruction after mastectomy is an established method, particularly in patients who have failed breast conserving therapy. This study presents comparison of prepectoral and subpectoral approach for two-stage prosthetic breast reconstruction with latissimus flap.MethodsA...
Sat Nov 09, 2019 18:39
Publication date: Available online 8 November 2019Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Shinsuke Akita, Yoshihisa Yamaji, Hideki Tokumoto, Haruka Maei, Takafumi Tezuka, Hideyuki Ogata, Kentaro Kosaka, Yoshitaka Kubota, Motone Kuriyama, Nobuyuki MitsukawaAbstractBackgroundIntraoperative retrograde blood flow from the vein to the lymphatic vessels in a lymphaticovenular anastomosis (LVA) for lower extremity lymphedema (LEL) leads to poor results. This study aimed...
Sat Nov 09, 2019 18:39
Publication date: November–December 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 6Author(s): Sergey Novikov, Pavel Krzhivitskii, Sergey Kanaev, Petr Krivorotko, Nikolay Ilin, Julia Melnik, Nadejda PopovaAbstractPurposeTo evaluate the opportunities of single photon emission tomography/computerized tomography (SPECT-CT) for localization of axillary sentinel lymph nodes (ASLNs) and subsequent radiotherapy planning in women with early breast cancer.Material and methodsIndividual...
Sat Nov 09, 2019 18:34
Publication date: November–December 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 6Author(s): Daisuke Kawahara, Shuichi Ozawa, Hisashi Nakano, Katsumaro Kubo, Takehiro Shiinoki, Tomoki Kimura, Yasushi NagataAbstractBackgroundPreviously, the physical dose-enhancement factor (DphysEF) enhancement was introduced. However, the dose enhancement considering the biological effectiveness was not shown.PurposeThe aim of the current study was to evaluate the biological dose-enhancement...
Sat Nov 09, 2019 18:34
Publication date: November 2019Source: Journal of Phonetics, Volume 77Author(s): Daniel J. OlsonAbstractPrevious research on the phonetics and phonology of code-switching has largely focused on word internal phenomenon, such as voice onset time. However, many phonological processes occur across word boundaries, and in the case of code-switching, potentially across language boundaries. This study examines the application of phonological rules across word and language boundaries in cases of code-switching,...
Sat Nov 09, 2019 18:30
Chronic kidney disease–associated pruritus, also known as uremic pruritus, is a common, distressing, and underrecognized condition that affects more than 60% of patients undergoing hemodialysis, with 20 to 40% of patients reporting moderate-to-severe pruritus. Intense and generalized systemic…
Fri Nov 08, 2019 02:00
Publication date: Available online 8 November 2019Source: Hearing ResearchAuthor(s): Liangcai Wan, Michael Lovett, Mark E. Warchol, Jennifer S. StoneAbstractHair cells in the auditory organ of the vertebrate inner ear are the sensory receptors that convert acoustic stimuli into electrical signals that are conveyed along the auditory nerve to the brainstem. Hair cells are highly susceptible to ototoxic drugs, infection, and acoustic trauma, which can cause cellular degeneration. In mammals, hair cells...
Sat Nov 09, 2019 18:24
Publication date: Available online 9 November 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Edina Dizdarevic, Torben Frøstrup Hansen, John Pløen, Lars Henrik Jensen, Jan Lindebjerg, Søren Rafaelsen, Anders Jakobsen, Ane AppeltAbstractBackgroundSurgery is standard treatment for rectal cancer, but neoadjuvant chemoradiotherapy (CRT) may result in clinical complete response (cCR) in select patients, allowing for non-surgical management (NSM). Prospective studies of...
Sat Nov 09, 2019 18:23
Publication date: Available online 8 November 2019Source: Medical HypothesesAuthor(s): Sungu Hwang, Young-Seuk Cho, Nam Lyong KangAbstractThe aim of this study was to determine the body mass index (BMI) for the best fitness and effective exercise. This study analyzed data from the Korean national fitness assessment by the Korea Institute of Sport Science (2017). The fitness tests considered were sit-up, standing long jump (SLJ), 20-m multi-stage shuttle run (20-m MSSR), and 10-m shuttle run (10-m...
Sat Nov 09, 2019 17:32
Publication date: Available online 9 November 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): R. Pribuisiene, A. Pasvenskaite, K. Pribuisis, T. Balsevicius, V. Liutkevicius, V. UlozaAbstractAimTo evaluate dysphonia rate and impact of vocal training in vocally trained (VT) and vocally untrained (VUT) children using the Lithuanian version of Glottal Function Index (GFI-LT) questionnaire.Methods262 children (age range from 6 to 16 years) were included into prospective study....
Sat Nov 09, 2019 17:30
Publication date: Available online 9 November 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Wynne Q. Zhang, Elton M. Lambert, Julina OngkasuwanAbstractIntroductionVocal fold movement impairment (VFMI) is a well-known sequela of cervical and thoracic procedures performed in the vicinity of the recurrent laryngeal nerve. Interpretation of flexible nasolaryngoscopy (FNL) can be difficult in young children due to crying, secretions, and obstructing supraglottic structures....
Sat Nov 09, 2019 17:30
Publication date: Available online 9 November 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Malika Dahmani, Sonia Talbi, Fatima Ammar-Khodja, Sofiane Ouhab, Farid Boudjenah, Merieme Djebbar, Crystel Bonnet, Christine PetitAbstractHereditary distal renal tubular acidosis (dRTA) is a rare disorder characterized by metabolic acidosis due to impaired renal acid excretion. To date, three genes (ATP6V1B1, ATP6V0A4 and SLC4A1) have been reported to be responsible for this...
Sat Nov 09, 2019 17:30
Publication date: Available online 9 November 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Maria Elena Cucuzza, Angela D’Ambra, Roberto Evola, Filippo Greco, Pierluigi SmilariAbstractGrisel’s syndrome (GS) is a non traumatic atlanto-axial rotatory subluxation of C1-C2 joint. A six year old girl, 20 days after an episode of fever, developed a torticollis and a 3/6 heart murmur. The echocardiography showed a Rheumatic Carditis. The Brain and cervical spine Magnetic resonance...
Sat Nov 09, 2019 17:30
Publication date: Available online 8 November 2019Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Ali Furkan Kamanli, Gökçen Çetinel, Mustafa Zahid YıldızAbstractPhotodynamic therapy (PDT) is an emerging treatment modality in various areas such as cancer treatment and disinfection. The photosensitizer and oxygen have crucial roles for effective PDT treatment. The quantitative evaluation of singlet oxygen, which is a gold standard for monitoring effective treatment, remains as an important...
Sat Nov 09, 2019 17:27
Sat Nov 09, 2019 15:43
Summary Purpose The primary objective was to determine the recommended Phase 2 dose (RP2D) of checkpoint kinase 1 inhibitor, prexasertib, in combination with the p38 mitogen-activated protein kinase inhibitor, ralimetinib, which may be safely administered to patients with advanced cancer. Methods This Phase 1, nonrandomized, open-label, dose-escalation study of prexasertib+ralimetinib included patients with advanced and/or metastatic cancer, followed by a planned cohort expansion...
Sat Nov 09, 2019 02:00
Publication date: Available online 8 November 2019Source: Revista de Logopedia, Foniatría y AudiologíaAuthor(s): Elizabeth Mendoza, Donna Jackson-MaldonadoResumenEl objetivo de este trabajo es determinar si las personas sordas usuarias de lengua de señas mexicana (LSM) activan la LSM en la lectura de palabras escritas en español. Se usaron pares de palabras semánticamente relacionadas y semánticamente no relacionadas, divididas a su vez 2 subgrupos, fonológicamente relacionadas y fonológicamente...
Sat Nov 09, 2019 17:09
Summary The PI3K/AKT/mTOR pathway activation plays a central role in glioblastoma multiforme (GBM) development and progression, and in resistance to anti-cancer therapies. Inhibition of the PI3K pathway has been shown to sensitize cultured glioma cells and tumor xenografts to the effects of temozolomide (TMZ) and radiation. Vistusertib is an oral inhibitor of mTORC1/2 complexes. The primary objective of this Canadian Cancer Trials Group phase I study was to determine the recommended...
Sat Nov 09, 2019 02:00
Abstract Objective Tracheo-oesophageal fistula (TOF) is a rare pathology. It can be congenital and concurrent with other congenital anomalies such as oesophageal atresia, laryngeal and tracheal agenesis, or it can be acquired. The purpose of this study was to analyse various management strategies and their outcomes in infants and children with TOF and identify potential areas for standardisation of the fistula repair procedures. ...
Sat Nov 09, 2019 02:00
Abstract Objectives The aim of the present study was to measure nasal mucociliary clearance (NMC) time in the patients with MS and to compare the findings with healthy population. Methods Totally 97 individuals including 47 patients with relapsing–remitting multiple sclerosis and 50 healthy volunteers were enrolled into the study. Saccharin clearance test...
Sat Nov 09, 2019 02:00
Publication date: Available online 9 November 2019Source: Journal of Communication DisordersAuthor(s): Kristian Emil KristoffersenAbstractPurposeIndividuals with 5p deletion syndrome (also known as cri du chat syndrome) have various speech and language problems. The aim of this work was to examine early gestural and lexical development in a boy with this syndrome and to see to what extent his skills in these areas were delayed and/or deviant when compared to typically developing children.MethodThe...
Sat Nov 09, 2019 17:00
New Findings What is the central question of this study? Despite dry mouth being a common problem, factors contributing to altered salivary quality are poorly understood. This study examined relationships between physical properties of saliva, protein composition and metabolite composition using a 1H‐NMR spectroscopy‐driven metabolomics approach. Capsaicin was used as a salivary stimulus. What is the main finding and its importance? We found that salivary citrate, one of the major endogenous...
Fri Nov 08, 2019 20:34
Abstract Purpose The extent to which smoking is associated with thyroid stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) when taking account of clinical variables including alcohol consumption is unclear. We aimed to determine associations of TSH, FT4, and FT3 levels with current smoking. Methods A cross-sectional study was...
Sat Nov 09, 2019 02:00
Abstract Drinks and foods may be thickened to improve swallowing safety for dysphagia patients, but the resultant consistencies are not always palatable. Characterising alternative appetising foods is an important task. The study aims to characterise the in vitro swallowing behaviour of specifically formulated thickened dysphagia fluids containing xanthan gum and/or starch with standard jellies and yoghurt using a validated mechanical model, the “Cambridge Throat”. Observing from...
Sat Nov 09, 2019 02:00
Key points •Exercise in patients with hypertension can be accompanied by an abnormal cardiovascular response that includes attenuated blood flow and an augmented pressor response. •Endothelin‐1, a very potent vasoconstrictor, is a key modulator of blood flow and pressure during in health and has been implicated as a potential cause of the dysfunction in hypertension. •We assessed the role of endothelin‐1, acting through endothelin A (ETA) receptors, in modulating the central and peripheral cardiovascular...
Sat Nov 09, 2019 12:08
Publication date: Available online 8 November 2019Source: Archives of Oral BiologyAuthor(s): Mei Yu, Guiyun Wu, Yiyang Chen, Hongtao Wang, Yongbo Gao, Anxun WangAbstractObjectiveTo provide a prognostic biomarker and a potential therapeutic target for tongue squamous cell carcinoma (TSCC).DesignScreening the prognostic genes of TSCC by bioinformatics, and verifying the correlation between the above genes and the prognosis of TSCC by experiments.ResultsTwenty-four common differentially expressed genes...
Sat Nov 09, 2019 16:25
Abstract This study aimed to determine the temperature increase on the root surface during warm vertical compaction using three different obturation systems. Forty-five human single-rooted premolars were randomly assigned to one of three experimental groups of 15 teeth each for obturation with a System B unit, an Elements Obturation Unit, or a B&L SuperEndo Alpha II unit. All teeth were filled using the continuous wave of condensation technique with a set temperature of 200 °C....
Sat Nov 09, 2019 02:00
Publication date: Available online 9 November 2019Source: Medical Image AnalysisAuthor(s): Mateusz Koziński, Agata Mosinska, Mathieu Salzmann, Pascal FuaAbstractThe difficulty of obtaining annotations to build training databases still slows down the adoption of recent deep learning approaches for biomedical image analysis. In this paper, we show that we can train a Deep Net to perform 3D volumetric delineation given only 2D annotations in Maximum Intensity Projections (MIP) of the training volumes....
Sat Nov 09, 2019 16:07
Publication date: Available online 8 November 2019Source: Medical Image AnalysisAuthor(s): Shi Yin, Qinmu Peng, Hongming Li, Zhengqiang Zhang, Xinge You, Katherine Fischer, Susan L. Furth, Gregory E. Tasian, Yong FanAbstractIt remains challenging to automatically segment kidneys in clinical ultrasound (US) images due to the kidneys’ varied shapes and image intensity distributions, although semi-automatic methods have achieved promising performance. In this study, we propose subsequent boundary distance...
Sat Nov 09, 2019 16:07
Publication date: November 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 5Author(s):
Sat Nov 09, 2019 15:34
Publication date: November 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 5Author(s):
Sat Nov 09, 2019 15:34
Publication date: November 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 5Author(s):
Sat Nov 09, 2019 15:34
Publication date: November 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 5Author(s):
Sat Nov 09, 2019 15:34
Abstract Magnetic resonance spectroscopy (MRS) is a research tool for measuring the concentration of metabolites such as GABA and glutamate in the brain. MEGA‐PRESS has been the preferred pulse sequence for GABA measurements due to low physiological GABA concentrations, hence low signal. To compensate, researchers incorporate long acquisition durations (7–10 min) making functional measurements of this metabolite challenging. Here, the acquisition duration and sample sizes required to detect specific...
Sat Nov 09, 2019 13:19
Abstract The cross‐talk between trigeminal ganglion (TG) neurons and satellite glial cells (SGCs) is crucial for the regulation of inflammatory orofacial pain. Substance P (SP) plays an important role by activating neurokinin (NK)‐I receptors in this cross‐talk. Activation of extracellular signal‐regulated kinase (ERK) 1/2, protein kinase A (PKA) and protein kinase C (PKC) in neurons and SGCs of peripheral ganglions by peripheral inflammation is associated with inflammatory hypersensitivity. This...
Sat Nov 09, 2019 12:25
Abstract Huntington's disease (HD) is an inherited neurodegenerative disease with clinical manifestations that involve motor, cognitive, and psychiatric deficits. Cross‐sectional Magnetic Resonance Imaging (MRI) studies have described the main cortical and subcortical macrostructural atrophy of HD. However, longitudinal studies characterizing progressive atrophy are lacking. This study aimed to describe the cortical and subcortical gray matter atrophy using complementary volumetric and surface‐based...
Sat Nov 09, 2019 11:50
Abstract Zebra finches (Taeniopygia guttata) use their voices for communication. Song structures in the songs of individual males are important for sound recognition in females. The caudomedial mesopallium (CMM) and nidopallium (NCM) are known to be essential higher auditory regions for sound recognition. These two regions have also been discussed with respect to their fundamental functions and song selectivity. To clarify their functions and selectivity, we investigated latencies and spiking patterns,...
Sat Nov 09, 2019 11:44
Publication date: Available online 8 November 2019Source: Journal of Neuroscience MethodsAuthor(s): Elsie Premereur, Thomas Decramer, Walter Coudyzer, Tom Theys, Peter JanssenAbstractBackgroundRecently, large-scale semi-chronic recording systems have been developed, unique in their capability to record simultaneously from multiple individually moveable electrodes. As these recording systems can cover a large area, knowledge of the exact location of each individual electrode is crucial. Currently,...
Sat Nov 09, 2019 15:23
Publication date: Available online 8 November 2019Source: Journal of Neuroscience MethodsAuthor(s): E.B. Tezikov, S.V. Pirozhkov, P.F. Litvitskiy, S.L. KarateevAbstractBackgroundIsolated brain of experimental animals is a useful model to study transport of substances, including drugs, across the blood-brain barrier, mechanisms of convulsive activity, ischemic and reperfusion brain injury. Normal functioning of neurons, especially cortical, in the central nervous system requires adequate supply of...
Sat Nov 09, 2019 15:23
Publication date: Available online 8 November 2019Source: Journal of Neuroscience MethodsAuthor(s): Jacob A. George, Tyler S. Davis, Mark R. Brinton, Gregory A. ClarkAbstractBackgroundMulti-articulate prostheses are capable of performing dexterous hand movements. However, clinically available control strategies fail to provide users with intuitive, independent and proportional control over multiple degrees of freedom (DOFs) in real-time.New MethodWe detail the use of a modified Kalman filter (MKF)...
Sat Nov 09, 2019 15:23
Publication date: Available online 8 November 2019Source: Journal of Neuroscience MethodsAuthor(s): Aaron M. Dingle, Jared P. Ness, Joseph Novello, Jacqueline S. Israel, Ruston Sanchez, Augusto X.T. Millevolte, Sarah Brodnick, Lisa Krugner-Higby, Brett Nemke, Yan Lu, Aaron J. Suminski, Mark D. Markel, Justin C. Williams, Samuel O. PooreAbstractBackgroundChronic stability and high degrees of selectivity are both essential but somewhat juxtaposed components for creating an implantable bi-directional...
Sat Nov 09, 2019 15:23
Publication date: Available online 9 November 2019Source: International Journal of PsychophysiologyAuthor(s): Kristina Eichel, Jutta StahlAbstractMindfulness seems to have an impact on error processing in simple response tasks, as former studies reported both an effect of mindfulness meditation on, as well as relationships to trait mindfulness with behavioral and neural correlates of error processing. However, the results of these studies showed no consistent pattern. To dismantle some of these findings,...
Sat Nov 09, 2019 15:23
Abstract Targeted therapy directed against oncogenic BRAF mutations and immune checkpoint inhibitors have transformed melanoma therapy over the past decade and prominently improved patient outcomes. However, not all patients will respond to targeted therapy or immunotherapy and many relapse after initially responding to treatment. This unmet need presents two major challenges. First, can we elucidate novel oncogenic drivers to provide new therapeutic targets? Second, can we identify patients who...
Sat Nov 09, 2019 13:09
Publication date: Available online 9 November 2019Source: Clinical TherapeuticsAuthor(s): Joy J. Jiang, Michelle Z. Fang, Sarah S. Jackson, Thomas R. O'Brien
Sat Nov 09, 2019 15:15
Publication date: Available online 9 November 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): José Luis Soto-Hernández, Adán Soto-Ramírez, Iván Pérez-Neri, Verónica Angeles Morales, Graciela Cárdenas, Victor Alcocer Barradas
Sat Nov 09, 2019 15:14
Publication date: Available online 8 November 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Charles-André Philip, Catherine Prouvot, Marion Cortet, Christian Bisch, Pierre de Saint-Hilaire, Emmanuelle Maissiat, Cyril Huissoud, Gil DubernardAbstractTridimensional rectosonography (3-D RSG) is a transvaginal ultrasonography procedure combining intrarectal contrast with tridimensional technology. The objectives of this study were to assess the diagnostic performances of 3-D RSG in deep infiltrating...
Sat Nov 09, 2019 15:12
Publication date: Available online 8 November 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Jipeng Yan, Xingchen Yang, Zhenfeng Chen, Honghai LiuAbstractIt is crucial to model skeletal muscles for muscle-centered health care, such as prosthetics. Here we hypothesize that the acoustic non-linearity parameter (B/A) can be utilized to partially represent the contraction state of skeletal muscles. Although previous work commonly measured the B/A value of tissues in vitro, the present study...
Sat Nov 09, 2019 15:12
Publication date: Available online 8 November 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Judy Yan, Melissa Yin, F. Stuart Foster, Christine E.M. DémoréAbstractGas vesicles (GVs) are nanosized structures (45–800 nm) and have been reported to produce non-linear contrast signals, making them an attractive agent for molecular targeting of tumors. One barrier to their use for pre-clinical oncology studies is rapid uptake into the reticuloendothelial system (RES) and consequent rapid decrease...
Sat Nov 09, 2019 15:12
Publication date: Available online 8 November 2019Source: Allergology InternationalAuthor(s): Shunsuke Takahagi, Akiko Kamegashira, Atsushi Fukunaga, Naoko Inomata, Takeshi Nakahara, Koremasa Hayama, Michihiro Hide
Sat Nov 09, 2019 14:52
Publication date: Available online 9 November 2019Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): O. Laccourreye
Sat Nov 09, 2019 14:31
Publication date: Available online 8 November 2019Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): L. Skoloudik, D. Kalfert, T. Valenta, V. Chrobok
Sat Nov 09, 2019 14:31
We describe the first case of hereditary spastic paraplegia (HSP) caused by a novel de novo (p.L337P) variant in ATP1A1. Evidences for the causative role of this variant are provided through functional and homology modelling studies. This finding expands the phenotypic spectrum of the ATP1A1‐related disorders, adds a small piece to the large genetic puzzle of HSP and increases knowledge on the molecular mechanisms underlying inherited axonopathies. ABSTRACT Dominant mutations in ATP1A1, encoding...
Fri Nov 08, 2019 19:29
Publication date: Available online 8 November 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Karina A. Barreiro, Riikka Tulamo, Annukka Jouppila, Anders Albäck, Riitta LassilaObjectivesVascular binding of dual antiplatelet and anticoagulant (APAC) was assessed in surgically created femoral arteriovenous fistula (AVF) and iliac and carotid artery injury in porcine models.MethodsThree models of collagen exposing injury were used: 1) femoral AVF, 2) in vivo iliac and carotid...
Sat Nov 09, 2019 14:14
Publication date: Available online 8 November 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Marek Kuzniar, Gustaf Tegler, Anders Wanhainen, Håkan Ahlström, Kevin Mani, Tomas HansenObjectiveThis study aimed to evaluate the feasibility of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) combined with contrast enhanced magnetic resonance imaging (MRI) to identify inflammation in asymptomatic abdominal aortic aneurysms (AAA).MethodsFDG PET/MRI was performed...
Sat Nov 09, 2019 14:14
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