JCM, Vol. 8, Pages 1896: Comprehensive Genomic Review of TCGA Head and Neck Squamous Cell Carcinomas (HNSCC) Journal of Clinical Medicine doi: 10.3390/jcm8111896 Authors: Mario Pérez Sayáns Cintia Micaela Chamorro Petronacci Alejandro Ismael Lorenzo Pouso Elena Padín Iruegas Andrés Blanco Carrión José Manuel Suárez Peñaranda Abel García García The aim of this present study was to comprehensively describe somatic DNA alterations and transcriptional alterations in the...
JCM, Vol. 8, Pages 1894: BoOne HeEalth ManageEment in Patients with Early Breast Cancer: A Retrospective Italian Osteoncology Center “Real-Life” Experience (BOHEME Study) Journal of Clinical Medicine doi: 10.3390/jcm8111894 Authors: Recine Bongiovanni Foca Mercatali Fausti Calpona Riva Vita Liverani Spadazzi Miserocchi Di Menna Gurrieri Cocchi Vespignani Ibrahim Debonis Background: We assessed the real-life clinical impact...
JCM, Vol. 8, Pages 1895: Molecular Scavengers, Oxidative Stress and Cardiovascular Disease Journal of Clinical Medicine doi: 10.3390/jcm8111895 Authors: Alessandro Di Minno Mariano Stornaiuolo Ettore Novellino Cardiovascular disease (CVD) is the number one cause of deaths worldwide, with yearly deaths due to atherothrombosis—i [...]
JCM, Vol. 8, Pages 1893: Associations between Plasma Biomarkers and Cognition in Patients with Alzheimer’s Disease and Amnestic Mild Cognitive Impairment: A Cross-Sectional and Longitudinal Study Journal of Clinical Medicine doi: 10.3390/jcm8111893 Authors: Tsai Liang Lee Su Lin Chu Tsai Lin Lin Yang Brain degeneration in patients with Alzheimer’s disease (AD) results from the accumulation of pathological amyloid- (Aβ) plaques and...
JCM, Vol. 8, Pages 1892: Insulin Resistance Associated Disorders Pivoting Long-Term Hepatitis B Surface Antigen Decline During Entecavir Therapy Journal of Clinical Medicine doi: 10.3390/jcm8111892 Authors: Lin Liu Hsu Lin Chiu Chiu Cheng Chen Chang Wu Insulin resistance associated disorders (IRAD), including prediabetes, type 2 diabetes mellitus (T2DM), and fatty liver are significant risk factors of liver-related death in chronic hepatitis B (CHB)....
JCM, Vol. 8, Pages 1890: An Intriguing Involvement of Mitochondria in Cystic Fibrosis Journal of Clinical Medicine doi: 10.3390/jcm8111890 Authors: Favia de Bari Bobba Atlante Cystic fibrosis (CF) occurs when the cystic fibrosis transmembrane conductance regulator (CFTR) protein is not synthetized and folded correctly. The CFTR protein helps to maintain the balance of salt and water on many body surfaces, such as the lung surface. When the protein is not working correctly,...
JCM, Vol. 8, Pages 1889: Recent Trends in Bacteriology of Adult Patients with Chronic Rhinosinusitis
JCM, Vol. 8, Pages 1889: Recent Trends in Bacteriology of Adult Patients with Chronic Rhinosinusitis Journal of Clinical Medicine doi: 10.3390/jcm8111889 Authors: Doyeon Kim Abdullah M. Assiri Ji Heui Kim This study aimed to identify trends in bacteria isolated from Korean adults with chronic rhinosinusitis (CRS). Enrolled were CRS patients who underwent sinus bacterial culture during endoscopic sinus surgery between 2007–2008, 2011–2012, and 2017–2018...
JCM, Vol. 8, Pages 1891: Complications in Total Joint Arthroplasties Journal of Clinical Medicine doi: 10.3390/jcm8111891 Authors: Enrique Gómez-Barrena Eduardo García-Rey Total joint arthroplasties (TJA) are today considered highly successful operations [...]
JCM, Vol. 8, Pages 1888: The Reciprocal Association between Problem Gambling and Mental Health Symptoms/Substance Use: Cross-Lagged Path Modelling of Longitudinal Cohort Data Journal of Clinical Medicine doi: 10.3390/jcm8111888 Authors: Nicki A. Dowling Carla A. Butera Stephanie S. Merkouris George J. Youssef Simone N. Rodda Alun C. Jackson To date, studies have highlighted cross-sectional and unidirectional prospective relationships between problem gambling and mental...
JCM, Vol. 8, Pages 1887: Neurocircuitry of Reward and Addiction: Potential Impact of Dopamine–Glutamate Co-release as Future Target in Substance Use Disorder Journal of Clinical Medicine doi: 10.3390/jcm8111887 Authors: Zisis Bimpisidis Åsa Wallén-Mackenzie Dopamine–glutamate co-release is a unique property of midbrain neurons primarily located in the ventral tegmental area (VTA). Dopamine neurons of the VTA are important for behavioral regulation in response to rewarding...
JCM, Vol. 8, Pages 1886: Myorelaxant Effect of Transdermal Cannabidiol Application in Patients with TMD: A Randomized, Double-Blind Trial Journal of Clinical Medicine doi: 10.3390/jcm8111886 Authors: Aleksandra Nitecka-Buchta Anna Nowak-Wachol Kacper Wachol Karolina Walczyńska-Dragon Paweł Olczyk Olgierd Batoryna Wojciech Kempa Stefan Baron (1) Background: The healing properties of cannabidiol (CBD) have been known for centuries. In this study, we aimed to evaluate...
JCM, Vol. 8, Pages 1885: Re: A Meta-Analysis of the Clinical Use of Curcumin for Irritable Bowel Syndrome Journal of Clinical Medicine doi: 10.3390/jcm8111885 Authors: Laura Appleton Andrew S. Day We read with interest the article by Ng et al [...]
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JoF, Vol. 5, Pages 103: Thermogenic Characterization and Antifungal Susceptibility of Candida auris by Microcalorimetry Journal of Fungi doi: 10.3390/jof5040103 Authors: Mariagrazia Di Luca Anna Koliszak Svetlana Karbysheva Anuradha Chowdhary Jacques F. Meis Andrej Trampuz Candida auris has emerged globally as a multidrug-resistant fungal pathogen. Isolates of C. auris are reported to be misidentified as Candida haemulonii. The aim of the study was to compare the heat...
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Medical Sciences, Vol. 7, Pages 103: Lead Exposure and Cardiovascular Disease among Young and Middle-Aged Adults Medical Sciences doi: 10.3390/medsci7110103 Authors: Emmanuel Obeng-Gyasi Lead and its effects on cardiovascular-related markers were explored in this cross-sectional study of young adults (18–44 years) and middle-aged adults (45–65 years) from the United States using the National Health and Nutrition Examination Survey (NHANES), 2009–2016. Degrees...
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Membranes, Vol. 9, Pages 146: Impact of Membrane Pore Size on the Clarification Performance of Grape Marc Extract by Microfiltration Membranes doi: 10.3390/membranes9110146 Authors: Mora Pérez Quezada Herrera Cassano Ruby-Figueroa The influence of membrane pore size on the permeate flux, fouling mechanism, and rejection of soluble and suspended solids, as well as of phenolics and anthocyanins, in the clarification of grape marc extract by microfiltration (MF) was...
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Metabolites, Vol. 9, Pages 268: Study of the Differentially Expressed Genes in the Pomacea canaliculata Transcriptome after Treatment with Pedunsaponin A Metabolites doi: 10.3390/metabo9110268 Authors: Chunping Yang Tianxing Lv Yangyang Zhang Bin Wang Xiaomin Zhao Min Zhang Guoshu Gong Xiaoli Chang Guizhou Yue Xiaoyan Qiu Liya Luo Huabao Chen Transcriptomes, genomes, and proteomes have played important roles in the search for drug targets. To determine...
Metabolites, Vol. 9, Pages 267: Intrauterine Growth Restriction: New Insight from the Metabolomic Approach Metabolites doi: 10.3390/metabo9110267 Authors: Elena Priante Giovanna Verlato Giuseppe Giordano Matteo Stocchero Silvia Visentin Veronica Mardegan Eugenio Baraldi Recognizing intrauterine growth restriction (IUGR) is a matter of great concern because this condition can significantly affect the newborn’s short- and long-term health. Ever since the first...
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Microorganisms, Vol. 7, Pages 534: Determining the Virulence Properties of Escherichia coli ST131 Containing Bacteriocin-Encoding Plasmids Using Short- and Long-Read Sequencing and Comparing Them with Those of Other E. coli Lineages Microorganisms doi: 10.3390/microorganisms7110534 Authors: da Cruz Campos Cavallo L. Andrade van Dijl Couto Zrimec Lo Ten Foe P. Rosa V. Damasco Friedrich Chlebowicz-Flissikowska Rossen Escherichia coli ST131...
Microorganisms, Vol. 7, Pages 535: Uncovering Bifidobacteria via Targeted Sequencing of the Mammalian Gut Microbiota Microorganisms doi: 10.3390/microorganisms7110535 Authors: Gabriele Andrea Lugli Sabrina Duranti Christian Milani Leonardo Mancabelli Francesca Turroni Douwe van Sinderen Marco Ventura Bifidobacteria are among the most prevalent gut commensals in mammals, playing crucial functional roles that start from their early colonization of the infant gastrointestinal...
Microorganisms, Vol. 7, Pages 533: Replenishment of Hepatitis B Virus cccDNA Pool Is Restricted by Baseline Expression of Host Restriction Factors In Vitro Microorganisms doi: 10.3390/microorganisms7110533 Authors: Sergey Brezgin Anastasiia Kostyusheva Ekaterina Bayurova Ilya Gordeychuk Maria Isaguliants Irina Goptar Anastasiia Nikiforova Valery Smirnov Elena Volchkova Dieter Glebe Dmitry Kostyushev Vladimir Chulanov Background: Covalently closed circular...
Microorganisms, Vol. 7, Pages 532: Screening of Various Metabolites in Six Barley Varieties Grown under Natural Climatic Conditions (2016–2018) Microorganisms doi: 10.3390/microorganisms7110532 Authors: Kristina Habschied Rudolf Krska Michael Sulyok Bojan Šarkanj Vinko Krstanović Alojzije Lalić Gordana Šimić Krešimir Mastanjević Climatic changes influence considerably the distribution and occurrence of different secondary metabolites in cereals. The aim of this investigation...
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Molecules, Vol. 24, Pages 4023: Mercury Determination in Natural Zeolites by Thermal Decomposition Atomic Absorption Spectrometry: Method Validation in Compliance with Requirements for Use as Dietary Supplements Molecules doi: 10.3390/molecules24224023 Authors: Senila Cadar Senila Hoaghia Miu Natural zeolites are hydrated aluminosilicate minerals that, due to their remarkable physical-chemical properties of being molecular sieves and cation exchangers, have applications...
Molecules, Vol. 24, Pages 4021: Chemical Composition and Antimicrobial Activity of Artemisia herba-alba and Origanum majorana Essential Oils from Morocco Molecules doi: 10.3390/molecules24224021 Authors: Amor Caputo La Storia De Feo Mauriello Fechtali Essential oils (EOs) are one of the most important groups of plant metabolites responsible for their biological activities. This study was carried out to study the chemical composition and the antimicrobial effects...
Molecules, Vol. 24, Pages 4020: Structure–Activity Relationship Study of Acyclic Terpenes in Blood Glucose Levels: Potential α-Glucosidase and Sodium Glucose Cotransporter (SGLT-1) Inhibitors Molecules doi: 10.3390/molecules24224020 Authors: Miguel Valdes Fernando Calzada Jessica Mendieta-Wejebe Twelve terpenoids were evaluated in the treatment of type 2 diabetes mellitus: seven monoterpenes (geranyl acetate (1), geranic acid (2), citral (3), geraniol (4), methyl geranate (5),...
Molecules, Vol. 24, Pages 4022: Development of an Oriental Medicine Discrimination Method through Analysis of Steroidal Saponins in Dioscorea nipponica Makino and Their Anti-Osteosarcoma Effects Molecules doi: 10.3390/molecules24224022 Authors: Joo Tae Hwang Ki-Sun Park Jin Ah Ryuk Hye Jin Kim Byoung Seob Ko To prevent confusing Dioscorea nipponica (DN), an Oriental medicine, with Dioscorea quinquelobata (DQ) and Dioscorea septemloba (DS), a simple and accurate quantitative...
Molecules, Vol. 24, Pages 4018: The Synthesis and Utility of Metal-Nitrosophenolato Compounds—Highlighting the Baudisch Reaction Molecules doi: 10.3390/molecules24224018 Authors: Nicholls Barber Baxendale The syntheses of the title compounds demonstrate a privileged introduction of a nitroso (and a hydroxyl via the Baudisch reaction) group to an aromatic ring. These complexes first appeared in the literature as early as 1939, and a range of applications has subsequently been...
Molecules, Vol. 24, Pages 4016: Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK) Molecules doi: 10.3390/molecules24224016 Authors: Christopher R. M. Asquith James M. Bennett Lianyong Su Tuomo Laitinen Jonathan M. Elkins Julie E. Pickett Carrow I. Wells Zengbiao Li Timothy M. Willson William J. Zuercher SGC-GAK-1 (1) is a potent, selective, cell-active chemical probe for cyclin G-associated kinase (GAK). However, 1 was...
Molecules, Vol. 24, Pages 4017: Correction: Tienaho, J., et al. Metabolic Profiling of Water-Soluble Compounds from the Extracts of Dark Septate Endophytic Fungi (DSE) Isolated from Scots Pine (Pinus sylvestris L.) Seedlings Using UPLC–Orbitrap–MS. Molecules 2019, 24, 2330 Molecules doi: 10.3390/molecules24224017 Authors: Tienaho Karonen Muilu–Mäkelä Wähälä Denegri Franzén Karp Santala Sarjala The authors wish to make the following corrections to this...
Molecules, Vol. 24, Pages 4019: Brief Story on Prostaglandins, Inhibitors of their Synthesis, Hematopoiesis, and Acute Radiation Syndrome Molecules doi: 10.3390/molecules24224019 Authors: Hofer Hoferová Falk Prostaglandins and inhibitors of their synthesis (cyclooxygenase (COX) inhibitors, non-steroidal anti-inflammatory drugs) were shown to play a significant role in the regulation of hematopoiesis. Partly due to their hematopoiesis-modulating effects, both prostaglandins and...
Molecules, Vol. 24, Pages 4015: Five New Meroterpenoids from the Fruiting Bodies of the Basidiomycete Clitocybe clavipes with Cytotoxic Activity Molecules doi: 10.3390/molecules24224015 Authors: Zhaocui Xudong Hanqiao Xinyi Guoxu Leiling Five new meroterpenoids, clavipols A–B (1–2) with a 12-membered ether ring and clavilactones G–I (3–5) having a 10-membered carbocycle connected to a hydroquinone and an α,β-epoxy/unsaturated...
Molecules, Vol. 24, Pages 4013: The Synthesis and Properties of Liquid Crystalline Polyurethanes, Chemically Modified by Polyhedral Oligomericsilsesquioxanes Molecules doi: 10.3390/molecules24224013 Authors: Artur Bukowczan Edyta Hebda Maciej Czajkowski Krzysztof Pielichowski In this work, we report for the first time on the influence of polyhedral oligomericsilsesquioxanes (POSS) on the structure and properties of liquid crystalline polyurethane (LCPU). LCPU/POSS hybrids were...
Molecules, Vol. 24, Pages 4014: Novel Isoxazolidine and γ-Lactam Analogues of Homonucleosides Molecules doi: 10.3390/molecules24224014 Authors: Dorota G. Piotrowska Iwona E. Głowacka Dominique Schols Robert Snoeck Graciela Andrei Joanna Gotkowska Homonucleoside analogues cis-16 and trans-17 having a (5-methoxycarbonyl)isoxazolidine framework were synthesized via the 1,3-dipolar cycloaddition of nucleobase-derived nitrones with methyl acrylate. Hydrogenolysis of the isoxazolidines...
Molecules, Vol. 24, Pages 4012: Deep Eutectic Solvents for Pretreatment, Extraction, and Catalysis of Biomass and Food Waste Molecules doi: 10.3390/molecules24224012 Authors: Payam Kalhor Khashayar Ghandi Valorization of lignocellulosic biomass and food residues to obtain valuable chemicals is essential to the establishment of a sustainable and biobased economy in the modern world. The latest and greenest generation of ionic liquids (ILs) are deep eutectic solvents (DESs) and natural...
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Nanomaterials, Vol. 9, Pages 1574: MOF-Derived Co3O4 Polyhedrons as Efficient Polysulfides Barrier on Polyimide Separators for High Temperature Lithium–sulfur Batteries Nanomaterials doi: 10.3390/nano9111574 Authors: Zhou Li Fang Zhao Wang Zhang Zhou The incorporation of highly polarized inorganic compounds in functional separators is expected to alleviate the high temperature safety- and performance-related issues for promising lithium–sulfur batteries....
Nanomaterials, Vol. 9, Pages 1575: Tumor Targeting by Monoclonal Antibody Functionalized Magnetic Nanoparticles Nanomaterials doi: 10.3390/nano9111575 Authors: Oltolina Colangelo Miletto Clemente Miola Verné Prat Follenzi Tumor-targeted drug-loaded nanocarriers represent innovative and attractive tools for cancer therapy. Several magnetic nanoparticles (MNPs) were analyzed as potential tumor-targeted drug-loaded nanocarriers after functionalization with anti-Met...
Nanomaterials, Vol. 9, Pages 1572: Hyaluronate Functionalized Multi-Wall Carbon Nanotubes Filled with Carboplatin as a Novel Drug Nanocarrier against Murine Lung Cancer Cells Nanomaterials doi: 10.3390/nano9111572 Authors: Daniel Salas-Treviño Odila Saucedo-Cárdenas María de Jesús Loera-Arias Humberto Rodríguez-Rocha Aracely García-García Roberto Montes-de-Oca-Luna Edgar I. Piña-Mendoza Flavio F. Contreras-Torres Gerardo García-Rivas Adolfo Soto-Domínguez Carbon...
Nanomaterials, Vol. 9, Pages 1571: Facile Fabrication of Flower-Like BiOI/BiOCOOH p–n Heterojunctions for Highly Efficient Visible-Light-Driven Photocatalytic Removal of Harmful Antibiotics Nanomaterials doi: 10.3390/nano9111571 Authors: Shijie Li Bing Xue Chunchun Wang Wei Jiang Shiwei Hu Yanping Liu Hengwei Wang Jianshe Liu Novel heterojunction photocatalysts with remarkable photocatalytic capabilities and durability for degrading recalcitrant contaminants are...
Nanomaterials, Vol. 9, Pages 1573: Label-Free MicroRNA Optical Biosensors Nanomaterials doi: 10.3390/nano9111573 Authors: Meimei Lai Gymama Slaughter MicroRNAs (miRNAs) play crucial roles in regulating gene expression. Many studies show that miRNAs have been linked to almost all kinds of disease. In addition, miRNAs are well preserved in a variety of specimens, thereby making them ideal biomarkers for biosensing applications when compared to traditional protein biomarkers. Conventional...
Nanomaterials, Vol. 9, Pages 1570: Calcium Phosphate Nanoparticles for Therapeutic Applications in Bone Regeneration Nanomaterials doi: 10.3390/nano9111570 Authors: Tanya J. Levingstone Simona Herbaj Nicholas J. Dunne Bone injuries and diseases constitute a burden both socially and economically, as the consequences of a lack of effective treatments affect both the patients’ quality of life and the costs on the health systems. This impended need has led the research community’s...
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Nutrients, Vol. 11, Pages 2690: Gut Microbiota and Obesity: A Role for Probiotics Nutrients doi: 10.3390/nu11112690 Authors: Ludovico Abenavoli Emidio Scarpellini Carmela Colica Luigi Boccuto Bahare Salehi Javad Sharifi-Rad Vincenzo Aiello Barbara Romano Antonino De Lorenzo Angelo A. Izzo Raffaele Capasso Nowadays, obesity is one of the most prevalent human health problems. Research from the last 30 years has clarified the role of the imbalance between energy...
Nutrients, Vol. 11, Pages 2689: The Utility of Thirst as a Measure of Hydration Status Following Exercise-Induced Dehydration Nutrients doi: 10.3390/nu11112689 Authors: William M. Adams Lesley W. Vandermark Luke N. Belval Douglas J. Casa The purpose of this study was to examine the perception of thirst as a marker of hydration status following prolonged exercise in the heat. Twelve men (mean ± SD; age, 23 ± 4 y; body mass, 81.4 ± 9.9 kg; height,...
Nutrients, Vol. 11, Pages 2688: Vegetarian Diets and Medical Expenditure in Taiwan—A Matched Cohort Study Nutrients doi: 10.3390/nu11112688 Authors: Chin-Lon Lin Jen-Hung Wang Chia-Chen Chang Tina H.T. Chiu Ming-Nan Lin Vegetarian diets and lifestyle have been shown to reduce the risk of many chronic non-communicable diseases, which now accounts for the major global burden of diseases. We aimed to determine the contribution of vegetarian diets and lifestyle to the actual...
Nutrients, Vol. 11, Pages 2687: Associations between 100% Orange Juice Consumption and Dietary, Lifestyle and Anthropometric Characteristics in a Cross-Sectional Study of U.S. Children and Adolescents Nutrients doi: 10.3390/nu11112687 Authors: Junichi R. Sakaki Melissa M. Melough Jing Li Rulla M. Tamimi Jorge E. Chavarro Ming-Hui Chen Ock K. Chun Concerns about orange juice’s sugar content have spurred discussions regarding its potential contributions to childhood...
Nutrients, Vol. 11, Pages 2683: Relationship of Excess Weight with Clinical Activity and Dietary Intake Deficiencies in Systemic Lupus Erythematosus Patients Nutrients doi: 10.3390/nu11112683 Authors: Mónica R. Meza-Meza Barbara Vizmanos-Lamotte José Francisco Muñoz-Valle Isela Parra-Rojas Marta Garaulet Bertha Campos-López Margarita Montoya-Buelna Sergio Cerpa-Cruz Erika Martínez-López Edith Oregon-Romero Ulises De la Cruz-Mosso Obesity and nutrients intake...
Nutrients, Vol. 11, Pages 2686: Associations of Circadian Eating Pattern and Diet Quality with Substantial Postpartum Weight Retention Nutrients doi: 10.3390/nu11112686 Authors: See Ling Loy Yin Bun Cheung Marjorelee T. Colega Airu Chia Chad Yixian Han Keith M. Godfrey Yap-Seng Chong Lynette Pei-Chi Shek Kok Hian Tan Ngee Lek Jerry Kok Yen Chan Mary Foong-Fong Chong Fabian Yap Besides food quantity and quality, food timing and frequency may contribute...
Nutrients, Vol. 11, Pages 2684: Challenges and Pitfalls in Human Milk Oligosaccharide Analysis Nutrients doi: 10.3390/nu11112684 Authors: Sander S. van Leeuwen Human milk oligosaccharides have been recognized as an important, functional biomolecule in mothers’ milk. Moreover, these oligosaccharides have been recognized as the third most abundant component of human milk, ranging from 10–15 g/L in mature milk and up to and over 20 g/L reported in colostrum. Initially,...
Nutrients, Vol. 11, Pages 2685: Flavonoid-Rich Mixed Berries Maintain and Improve Cognitive Function Over a 6 h Period in Young Healthy Adults Nutrients doi: 10.3390/nu11112685 Authors: Adrian R. Whyte Nancy Cheng Laurie T. Butler Daniel J. Lamport Claire M. Williams Research with young adults has previously indicated flavonoid-rich berry interventions facilitate improved executive function (EF) and positive affect 20 min–2 h post-dosing. There has been little consideration...
Nutrients, Vol. 11, Pages 2682: A Critical Appraisal of Strategies to Optimize Vitamin D Status in Germany, a Population with a Western Diet Nutrients doi: 10.3390/nu11112682 Authors: Roman Saternus Thomas Vogt Jörg Reichrath During the last decade, our scientific knowledge of the pleiotropic biological effects of vitamin D metabolites and their relevance to human health has expanded widely. Beyond the well-known key role of vitamin D in calcium homeostasis and bone health, it...
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Pathogens, Vol. 8, Pages 224: Evolution of H5-Type Avian Influenza A Virus Towards Mammalian Tropism in Egypt, 2014 to 2015 Pathogens doi: 10.3390/pathogens8040224 Authors: Sara Hussein Mahmoud Ahmed Mostafa Rabeh El-Shesheny Mohamed Zakaraia Seddik Galal Khalafalla Mahmoud Shehata Ahmed Kandeil Stephan Pleschka Ghazi Kayali Richard Webby Veljko Veljkovic Mohamed Ahmed Ali Highly pathogenic avian influenza viruses (HPAIV) of the H5-subtype have circulated...
Pathogens, Vol. 8, Pages 223: Renal Injury in DENV-4 Fatal Cases: Viremia, Immune Response and Cytokine Profile Pathogens doi: 10.3390/pathogens8040223 Authors: Priscila Conrado Guerra Nunes Lilimar da Silveira Rioja Janice Mery Chicarino de Oliveira Coelho Natália Gedeão Salomão Kíssila Rabelo Carollina Ceia José Francisco das Chagas de Carvalho Rodrigues Elzinandes Leal de Azeredo Carlos Alberto Basílio-de-Oliveira Rodrigo Basílio-de-Oliveira Rita Maria Ribeiro...
Pathogens, Vol. 8, Pages 222: Virulence and Pathogenicity Properties of Aggregatibacter actinomycetemcomitans Pathogens doi: 10.3390/pathogens8040222 Authors: Belibasakis Maula Bao Lindholm Bostanci Oscarsson Ihalin Johansson Aggregatibacter actinomycetemcomitans is a periodontal pathogen colonizing the oral cavity of a large proportion of the human population. It is equipped with several potent virulence factors that can cause cell death and induce or evade...
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Pharmaceutics, Vol. 11, Pages 581: Doxorubicin-Loaded Delta Inulin Conjugates for Controlled and Targeted Drug Delivery: Development, Characterization, and In Vitro Evaluation Pharmaceutics doi: 10.3390/pharmaceutics11110581 Authors: Lixin Wang Yunmei Song Ankit Parikh Paul Joyce Rosa Chung Liang Liu Franklin Afinjuomo John D. Hayball Nikolai Petrovsky Thomas G. Barclay Sanjay Garg Delta inulin, also known as microparticulate inulin (MPI), was modified by...
Pharmaceutics, Vol. 11, Pages 582: Folate Receptor-Targeting and Reactive Oxygen Species-Responsive Liposomal Formulation of Methotrexate for Treatment of Rheumatoid Arthritis Pharmaceutics doi: 10.3390/pharmaceutics11110582 Authors: Chen Amerigos J.C. Su Guissi Xiao Zong Ping Multifunctional nanomedicines with active targeting and stimuli-responsive drug release function utilizing pathophysiological features of the disease are regarded as an effective strategy...
Pharmaceutics, Vol. 11, Pages 580: Production and Application of Multicistronic Constructs for Various Human Disease Therapies Pharmaceutics doi: 10.3390/pharmaceutics11110580 Authors: Alisa A. Shaimardanova Kristina V. Kitaeva Ilmira I. Abdrakhmanova Vladislav M. Chernov Catrin S. Rutland Albert A. Rizvanov Daria S. Chulpanova Valeriya V. Solovyeva The development of multicistronic vectors has opened up new opportunities to address the fundamental issues of molecular...
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Plants, Vol. 8, Pages 478: Interaction of Carbohydrate Coated Cerium-Oxide Nanoparticles with Wheat and Pea: Stress Induction Potential and Effect on Development Plants doi: 10.3390/plants8110478 Authors: Ivana Milenković Aleksandra Mitrović Manuel Algarra Juan M. Lázaro-Martínez Enrique Rodríguez-Castellón Vuk Maksimović Slađana Z. Spasić Vladimir P. Beškoski Ksenija Radotić : Reports about the influence of cerium-oxide nanoparticles (nCeO2) on plants are contradictory...
Plants, Vol. 8, Pages 479: Plant Taxonomic Diversity Better Explains Soil Fungal and Bacterial Diversity than Functional Diversity in Restored Forest Ecosystems Plants doi: 10.3390/plants8110479 Authors: Hanif Guo Moniruzzaman He Yu Rao Liu Tan Shen Plant attributes have direct and indirect effects on soil microbes via plant inputs and plant-mediated soil changes. However, whether plant taxonomic and functional diversities can explain the soil microbial...
Plants, Vol. 8, Pages 476: Chloroplast Genome Sequence of Artemisia scoparia: Comparative Analyses and Screening of Mutational Hotspots Plants doi: 10.3390/plants8110476 Authors: Shabina Iram Muhammad Qasim Hayat Muhammad Tahir Alvina Gul Abdullah Ibrar Ahmed Artemisia L. is among the most diverse and medicinally important genera of the plant family Asteraceae. Discrepancies arise in the taxonomic classification of Artemisia due to the occurrence of multiple polyploidy...
Plants, Vol. 8, Pages 477: Predictive Binding Affinity of Plant-Derived Natural Products Towards the Protein Kinase G Enzyme of Mycobacterium tuberculosis (MtPknG) Plants doi: 10.3390/plants8110477 Authors: Qasaymeh Rotondo Oosthuizen Lall Seidel Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a growing public health concern worldwide, especially with the emerging challenge of drug resistance to the current drugs. Efforts to discover and develop novel, more...
Plants, Vol. 8, Pages 475: Two SNP Mutations Turned off Seed Shattering in Rice Plants doi: 10.3390/plants8110475 Authors: Yu Zhang Jiawu Zhou Ying Yang Walid Hassan Elgamal Peng Xu Jing Li Yasser Z. El-Refaee Suding Hao Dayun Tao Seed shattering is an important agronomic trait in rice domestication. In this study, using a near-isogenic line (NIL-hs1) from Oryza barthii, we found a hybrid seed shattering phenomenon between the NIL-hs1 and its recurrent parent,...
Plants, Vol. 8, Pages 474: Comparative Proteomics Reveals Cold Acclimation Machinery Through Enhanced Carbohydrate and Amino Acid Metabolism in Wucai (Brassica Campestris L.) Plants doi: 10.3390/plants8110474 Authors: Lingyun Yuan Shilei Xie Libing Nie Yushan Zheng Jie Wang Ju Huang Mengru Zhao Shidong Zhu Jinfeng Hou Guohu Chen Chenggang Wang Limited information is available on the cold acclimation of non-heading Chinese cabbage (NHCC) under low temperatures....
Plants, Vol. 8, Pages 473: Identification and Expression Analysis of Gretchen Hagen 3 (GH3) in Kiwifruit (Actinidia chinensis) During Postharvest Process Plants doi: 10.3390/plants8110473 Authors: Zengyu Gan Liuying Fei Nan Shan Yongqi Fu Jinyin Chen In plants, the Gretchen GH3 (GH3) protein is involved in free auxin (IAA) and amino acid conjugation, thus controlling auxin homeostasis. To date, many GH3 gene families have been identified from different plant species. However,...
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Religions, Vol. 10, Pages 616: Contempt and Labour: An Exploration through Muslim Barbers of South Asia Religions doi: 10.3390/rel10110616 Authors: Amir This article explores historical shifts in the ways the Muslim barbers of South Asia are viewed and the intertwined ways they are conceptualised. Tracing various concepts, such as caste identity, and their multiple links to contempt, labour and Islamic ethical discourses and practices, this article demonstrates shifting meanings of...
Religions, Vol. 10, Pages 615: Disney’s Reel Doubling of Violent Desire in J. J. Abrams’ Mimetic The Force Awakens Religions doi: 10.3390/rel10110615 Authors: John C. McDowell Abrams’ spectacularly distended infantilising manipulation of the saga embeds a form of cognitive resonance with a state of perpetual war and a politically thanatising mythos fitted out as a politically containing moment within what cultural commentators are referring to as “post-9/11 American...
Religions, Vol. 10, Pages 614: Yah’s Exemplary Soldiers: African Hebrew Israelites in the Israel Defense Forces Religions doi: 10.3390/rel10110614 Authors: Andrew Esensten This article considers the process of identity formation among soldiers in the Israel Defense Forces (IDF) who were born into the African Hebrew Israelites of Jerusalem (AHIJ), more commonly known as the Black Hebrews. The AHIJ are a sect of African Americans who began settling in Israel in 1969 and who identify as...
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Safety, Vol. 5, Pages 80: Safety Issues in the Seismic Design of Secondary Frameless Glass Structures Safety doi: 10.3390/safety5040080 Authors: Bedon Amadio Noé Glass is largely used in buildings, in the form of an innovative and versatile material. Both for novel and existing constructions, secondary glass systems are frequently realized to interact with primary components of different materials. In most cases, the structural challenge deriving from the intrinsic brittleness...
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Smart Cities, Vol. 2, Pages 496-511: A Methodology to Model Integrated Smart City System from the Information Perspective Smart Cities doi: 10.3390/smartcities2040030 Authors: Jules Muvuna Tuleen Boutaleb Keith J Baker Slobodan B Mickovski Rapid urban population growth challenges cities and sustainable urban development. Despite the effort deployed with conventional urban design, the current solutions are unable to significantly respond to existing challenges. The concept of...
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Toxins, Vol. 11, Pages 646: A Novel Niosome-Encapsulated Essential Oil Formulation to Prevent Aspergillus flavus Growth and Aflatoxin Contamination of Maize Grains During Storage Toxins doi: 10.3390/toxins11110646 Authors: García-Díaz Patiño Vázquez Gil-Serna Aflatoxin (AF) contamination of maize is a major concern for food safety. The use of chemical fungicides is controversial, and it is necessary to develop new effective methods to control Aspergillus flavus growth and,...
Toxins, Vol. 11, Pages 647: FGF23 and Phosphate–Cardiovascular Toxins in CKD Toxins doi: 10.3390/toxins11110647 Authors: Vogt Leifheit-Nestler Elevated levels of fibroblast growth factor 23 (FGF23) and phosphate are highly associated with increased cardiovascular disease and mortality in patients suffering from chronic kidney disease (CKD). As the kidney function declines, serum phosphate levels rise and subsequently induce the secretion of the phosphaturic hormone FGF23. In early...
Toxins, Vol. 11, Pages 645: Toxin Production in Soybean (Glycine max L.) Plants with Charcoal Rot Disease and by Macrophomina phaseolina, the Fungus that Causes the Disease Toxins doi: 10.3390/toxins11110645 Authors: Hamed K. Abbas Nacer Bellaloui Cesare Accinelli James R. Smith W. Thomas Shier Charcoal rot disease, caused by the fungus Macrophomina phaseolina, results in major economic losses in soybean production in southern USA. M. phaseolina has been proposed to use the...
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Vaccines, Vol. 7, Pages 177: Parenterally Administered P24-VP8* Nanoparticle Vaccine Conferred Strong Protection against Rotavirus Diarrhea and Virus Shedding in Gnotobiotic Pigs Vaccines doi: 10.3390/vaccines7040177 Authors: Ramesh Mao Lei Twitchell Shiraz Jiang Tan Yuan Current live rotavirus vaccines are costly with increased risk of intussusception due to vaccine replication in the gut of vaccinated children. New vaccines with improved safety and cost-effectiveness...
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Viruses, Vol. 11, Pages 1034: Prevalences of Pospiviroid Contamination in Large Seed Lots of Tomato and Capsicum, and Related Seed Testing Considerations Viruses doi: 10.3390/v11111034 Authors: David Dall Lindsay Penrose Andrew Daly Fiona Constable Mark Gibbs Analyses of pospiviroids in commercial seed lots of tomato and capsicum, determined by testing of 12,000 to 40,000 seeds per lot, have enabled the development of empirically-derived distribution curves for the observed...
Viruses, Vol. 11, Pages 1033: Meta-Transcriptomic Comparison of the RNA Viromes of the Mosquito Vectors Culex pipiens and Culex torrentium in Northern Europe Viruses doi: 10.3390/v11111033 Authors: Pettersson Shi Eden Holmes Hesson Mosquitoes harbor an extensive diversity of ‘insect-specific’ RNA viruses in addition to those important to human and animal health. However, because most studies of the mosquito virome have been conducted at lower latitudes,...
Viruses, Vol. 11, Pages 1032: The Effect of Sample Bias and Experimental Artefacts on the Statistical Phylogenetic Analysis of Picornaviruses Viruses doi: 10.3390/v11111032 Authors: Yulia Vakulenko Andrei Deviatkin Alexander Lukashev Statistical phylogenetic methods are a powerful tool for inferring the evolutionary history of viruses through time and space. The selection of mathematical models and analysis parameters has a major impact on the outcome, and has been relatively well-described...
Viruses, Vol. 11, Pages 1031: Isolation and Characterization of Clinical RSV Isolates in Belgium during the Winters of 2016–2018 Viruses doi: 10.3390/v11111031 Authors: Winke Van der Gucht Kim Stobbelaar Matthias Govaerts Thomas Mangodt Cyril Barbezange Annelies Leemans Benedicte De Winter Steven Van Gucht Guy Caljon Louis Maes Jozef De Dooy Philippe Jorens Annemieke Smet Paul Cos Stijn Verhulst Peter L. Delputte Respiratory Syncytial Virus...
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Water, Vol. 11, Pages 2323: Numerical Investigation of Techno-Economic Multiobjective Optimization of Geothermal Water Reservoir Development: A Case Study of China Water doi: 10.3390/w11112323 Authors: Zhang Wang Song Xie Fan Sun Du Renewable geothermal utilization is a significant approach for residential heating with two principal modes, direct geothermal district heating systems (DGDHSs) and indirect geothermal district heating systems (IGDHSs). The key principle...
Water, Vol. 11, Pages 2321: Integrated Modelling for Groundwater Contamination from Polluted Streams Using New Protection Process Techniques Water doi: 10.3390/w11112321 Authors: Abd-Elaty Zelenakova Straface Vranayová Abu-hashim Evaluating water quality indicators is a crucial issue in integrated water resource management, since potable water is an essential resource for the world's health and sustainable development. The current study was developed using a coupled...
Water, Vol. 11, Pages 2322: Advances in Deriving the Exact Distribution of Maximum Annual Daily Precipitation Water doi: 10.3390/w11112322 Authors: De Michele Maximum annual daily precipitation does not attain asymptotic conditions. Consequently, the results of classical extreme value theory do not apply to this variable. This issue has raised concerns about the frequent use of asymptotic distributions to model the maximum annual daily precipitation and, at the same time, has rekindled...
Water, Vol. 11, Pages 2320: Measuring Surface Velocity of Water Flow by Dense Optical Flow Method Water doi: 10.3390/w11112320 Authors: Wu Zhao Gan Ma Recent advances in video processing technology have provided a new approach to measuring the surface velocity of water flow (SVWF). However, most of the previous researches using video processing technology depended on tracers for target tracing, requiring spraying tracers in the measurement process. These methods are not...
Water, Vol. 11, Pages 2318: Improving Water Management Education across the Latin America and Caribbean Region Water doi: 10.3390/w11112318 Authors: Steve W. Lyon Peter Goethals Petra Schneider Luis Dominguez-Granda Henrietta Hampel Norris Lam Indira Nolivos Frido Reinstorf Raymundo C. Rodríguez Tejeda Raúl F. Vázquez Long Ho Education can help secure inclusive and resilient development around water resources. However, it is difficult to provide the latest...
Water, Vol. 11, Pages 2319: Gully Erosion Susceptibility Mapping Using Multivariate Adaptive Regression Splines—Replications and Sample Size Scenarios Water doi: 10.3390/w11112319 Authors: Javidan Kavian Pourghasemi Conoscenti Jafarian Soil erosion is a serious problem affecting numerous countries, especially, gully erosion. In the current research, GIS techniques and MARS (Multivariate Adaptive Regression Splines) algorithm were considered to evaluate gully erosion...
Water, Vol. 11, Pages 2316: Contamination Profiles of Perfluoroalkyl Substances (PFAS) in Groundwater in the Alluvial–Pluvial Plain of Hutuo River, China Water doi: 10.3390/w11112316 Authors: Yan Liu Xue Li Xing Wang Xiaocui Qiao Shuran Hao Jingrang Lu Xiaodi Duan Dionysios D. Dionysiou Binghui Zheng Over the past decade, concerns about perfluoroalkyl substances (PFAS) have increased rapidly among the scientific community due to their global distribution and persistence...
Water, Vol. 11, Pages 2317: Experimental Investigation of Flow Characteristics in Porous Media at Low Reynolds Numbers (Re→0) under Different Constant Hydraulic Heads Water doi: 10.3390/w11112317 Authors: Lili Wang Yunliang Li Guizhang Zhao Nanxiang Chen Yuanzhi Xu Understanding natural flows in porous media with low Reynolds number (Re) has significant implications for both science and engineering. However, knowledge and experimental gaps remain regarding such natural flows....
Water, Vol. 11, Pages 2315: Revisiting Telemetry in Pakistan’s Indus Basin Irrigation System Water doi: 10.3390/w11112315 Authors: Muhammad Tousif Bhatti Arif A. Anwar Muhammad Azeem Ali Shah The Indus Basin Irrigation System (IBIS) lacks a system for measuring canal inflows, storages, and outflows that is trusted by all parties, transparent, and accessible. An earlier attempt for telemetering flows in the IBIS did not deliver. There is now renewed interest in revisiting telemetry...
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