JCM, Vol. 8, Pages 2041: Prognostic Value of MiR-21: An Updated Meta-Analysis in Head and Neck Squamous Cell Carcinoma (HNSCC) Journal of Clinical Medicine doi: 10.3390/jcm8122041 Authors: Irimie-Aghiorghiesei Pop-Bica Pintea Braicu Cojocneanu Zimța Gulei Slabý Berindan-Neagoe Head and neck squamous cell carcinoma (HNSCC) is a group of malignancies with serious impact on patient quality of life due to a reduced rate of response to chemotherapy or radiation...
Thu Nov 21, 2019 02:00
JCM, Vol. 8, Pages 2043: Influence of the Sense of Coherence, the Doctor–Patient Relationship, Optimism and Non-Haematological Adverse Reactions on Health-Related Quality of Life in Patients with Breast Cancer Journal of Clinical Medicine doi: 10.3390/jcm8122043 Authors: Prieto-Callejero Rivera Andrés-Villas Gómez-Salgado Breast cancer is the most common malignant tumour in women around the world. The objective of this study was to quantify the number of non-haematological...
Thu Nov 21, 2019 02:00
JCM, Vol. 8, Pages 2039: Low Dose Low-Molecular-Weight Heparin for Thrombosis Prophylaxis: Systematic Review with Meta-Analysis and Trial Sequential Analysis Journal of Clinical Medicine doi: 10.3390/jcm8122039 Authors: Eck Bult Wetterslev Gans Meijer van der Horst Keus International guidelines recommend low-molecular-weight heparin (LMWH) as first-line pharmacological option for the prevention of venous thromboembolism (VTE) in many patient categories. Guidance...
Thu Nov 21, 2019 02:00
JCM, Vol. 8, Pages 2035: Anti-ApoA-1 IgGs in Familial Hypercholesterolemia Display Paradoxical Associations with Lipid Profile and Promote Foam Cell Formation Journal of Clinical Medicine doi: 10.3390/jcm8122035 Authors: Pagano Magenta D’Agostino Martino Barillà Satta Frias Ronca Mach Gencer Favari Vuilleumier Aims: Anti-Apolipoprotein A-1 autoantibodies (anti-ApoA-1 IgG) promote atherogenesis via innate immune receptors, and may impair cellular...
Thu Nov 21, 2019 02:00
JCM, Vol. 8, Pages 2038: Interstitial Lung Disease in Rheumatoid Arthritis Remains a Challenge for Clinicians Journal of Clinical Medicine doi: 10.3390/jcm8122038 Authors: Bendstrup Møller Kronborg-White Prior Hyldgaard Interstitial lung disease (ILD) is a serious complication of rheumatoid arthritis (RA) contributing to significantly increased morbidity and mortality. Other respiratory complications, such as chronic obstructive pulmonary disease and bronchiectasis,...
Thu Nov 21, 2019 02:00
JCM, Vol. 8, Pages 2037: Electrochemical Disinfection of Experimentally Infected Teeth by Boron-Doped Diamond Electrode Treatment Journal of Clinical Medicine doi: 10.3390/jcm8122037 Authors: Böhm Koch Rosiwal Burkovski Karl Grobecker-Karl Disinfection and prevention of re-infection are the decisive treatment steps in endodontic therapy. In this study, boron-doped diamond (BDD) electrodes have been fabricated and used for disinfecting the root canals of extracted...
Thu Nov 21, 2019 02:00
JCM, Vol. 8, Pages 2036: Tissue Sodium Content and Arterial Hypertension in Obese Adolescents Journal of Clinical Medicine doi: 10.3390/jcm8122036 Authors: Roth Markó Birukov Hennemuth Kühnen Jones Ghorbani Linz Müller Wiegand Berger Kuehne Kelm Early-onset obesity is known to culminate in type 2 diabetes, arterial hypertension and subsequent cardiovascular disease. The role of sodium (Na+) homeostasis in this process is incompletely understood,...
Thu Nov 21, 2019 02:00
JCM, Vol. 8, Pages 2033: Pathophysiological Implication of Fetuin-A Glycoprotein in the Development of Metabolic Disorders: A Concise Review Journal of Clinical Medicine doi: 10.3390/jcm8122033 Authors: Bourebaba Marycz : Alpha 2-Heremans-Schmid glycoprotein, also known as fetuin-A (Fet-A), is a multifunctional plasma glycoprotein that has been identified in both animal and human beings. The protein is a hepatokine predominantly synthesized in the liver, which is considered as an...
Thu Nov 21, 2019 02:00
JCM, Vol. 8, Pages 2034: Comparison of Renal Function Estimation Formulae for Dosing Direct Oral Anticoagulants in Patients with Atrial Fibrillation Journal of Clinical Medicine doi: 10.3390/jcm8122034 Authors: Lee Choi Kim Boo Kim Choi Choi Kim Lee Roh Shim Kim Kim The Cockcroft-Gault (CG) formula is recommended to guide clinicians in the choice of the appropriate dosage for direct oral anticoagulants (DOACs). However, the performance...
Thu Nov 21, 2019 02:00
JCM, Vol. 8, Pages 2032: Volume-Controlled Versus Dual-Controlled Ventilation during Robot-Assisted Laparoscopic Prostatectomy with Steep Trendelenburg Position: A Randomized-Controlled Trial Journal of Clinical Medicine doi: 10.3390/jcm8122032 Authors: Park Park Choi Eum Kim Dual-controlled ventilation (DCV) combines the advantages of volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV). Carbon dioxide (CO2) pneumoperitoneum and steep Trendelenburg...
Thu Nov 21, 2019 02:00
Life, Vol. 9, Pages 86: Survivability of Anhydrobiotic Cyanobacteria in Salty Ice: Implications for the Habitability of Icy Worlds Life doi: 10.3390/life9040086 Authors: Barbara Cosciotti Amedeo Balbi Alessandra Ceccarelli Claudia Fagliarone Elisabetta Mattei Sebastian Emanuel Lauro Federico Di Paolo Elena Pettinelli Daniela Billi Two anhydrobiotic strains of the cyanobacterium Chroococcidiopsis, namely CCMEE 029 and CCMEE 171, isolated from the Negev Desert in...
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Medicina, Vol. 55, Pages 754: Role of BRAF in Hepatocellular Carcinoma: A Rationale for Future Targeted Cancer Therapies Medicina doi: 10.3390/medicina55120754 Authors: Gnoni Licchetta Memeo Argentiero Solimando Longo Delcuratolo Brunetti The few therapeutic strategies for advance hepatocellular carcinoma (HCC) on poor knowledge of its biology. For several years, sorafenib, a tyrosine kinase inhibitors (TKI) inhibitor, has been the approved treatment option,...
Thu Nov 21, 2019 02:00
Metabolites, Vol. 9, Pages 285: Experimental Design and Sample Preparation in Forest Tree Metabolomics Metabolites doi: 10.3390/metabo9120285 Authors: Ana M. Rodrigues Ana I. Ribeiro-Barros Carla António Appropriate experimental design and sample preparation are key steps in metabolomics experiments, highly influencing the biological interpretation of the results. The sample preparation workflow for plant metabolomics studies includes several steps before metabolite extraction...
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Metabolites, Vol. 9, Pages 284: Serum Steroid Profiling by Liquid Chromatography–Tandem Mass Spectrometry for the Rapid Confirmation and Early Treatment of Congenital Adrenal Hyperplasia: A Neonatal Case Report Metabolites doi: 10.3390/metabo9120284 Authors: Cicalini Tumini Guidone Pieragostino Zucchelli Franchi Lisi Lelli Chiesa Stuppia Laurenzi Rossi Congenital adrenal hyperplasia (CAH) describes a group of autosomal recessive disorders of steroid...
Thu Nov 21, 2019 02:00
Microorganisms, Vol. 7, Pages 598: Environmental Filtering Drives the Assembly of Habitat Generalists and Specialists in the Coastal Sand Microbial Communities of Southern ChinaMicroorganisms doi: 10.3390/microorganisms7120598Authors: Hu Wang Cao Rashid Li YuCoastal sands harbor diverse microbial assemblages that play a critical role in the biogeochemical cycling of beach ecosystems. However, little is known about the relative importance of the different ecological processes underlying the assembly...
Thu Nov 21, 2019 02:00
Microorganisms, Vol. 7, Pages 597: Gut Anaerobes Capable of Chicken Caecum ColonisationMicroorganisms doi: 10.3390/microorganisms7120597Authors: Kubasova Kollarcikova Crhanova Karasova Cejkova Sebkova Matiasovicova Faldynova Sisak Babak Pokorna Cizek RychlikChicks in commercial production are highly sensitive to enteric infections and their resistance can be increased by administration of complex adult microbiota. However, it is not known which adult microbiota members are capable of colonising the...
Thu Nov 21, 2019 02:00
Microorganisms, Vol. 7, Pages 599: Bifidobacterial Distribution Across Italian Cheeses Produced from Raw MilkMicroorganisms doi: 10.3390/microorganisms7120599Authors: Milani Alessandri Mancabelli Lugli Longhi Anzalone Viappiani Duranti Turroni Ossiprandi van Sinderen VenturaCheese microbiota is of high industrial relevance due to its crucial role in defining the organoleptic features of the final product. Nevertheless, the composition of and possible microbe–microbe interactions between...
Thu Nov 21, 2019 02:00
Microorganisms, Vol. 7, Pages 596: Dietary Saccharomyces cerevisiae boulardii CNCM I-1079 Positively Affects Performance and Intestinal Ecosystem in Broilers during a Campylobacter jejuni InfectionMicroorganisms doi: 10.3390/microorganisms7120596Authors: Massacci Lovito Tofani Tentellini Genovese De Leo Papa Magistrali Manuali Trabalza-Marinucci Moscati ForteIn poultry production, probiotics have shown promise to limit campylobacteriosis at the farm level, the most commonly reported zoonosis in Europe....
Thu Nov 21, 2019 02:00
Microorganisms, Vol. 7, Pages 595: Dynamic Succession of Microbiota during Ensiling of Whole Plant Corn Following Inoculation with Lactobacillus buchneri and Lactobacillus hilgardii Alone or in CombinationMicroorganisms doi: 10.3390/microorganisms7120595Authors: Drouin Tremblay Chaucheyras-DurandLactic acid bacteria (LAB) used as silage additives have been shown to improve several fermentation parameters, including aerobic stability. Inoculation with a combination of Lactobacillus buchneri NCIMB40788...
Thu Nov 21, 2019 02:00
Microorganisms, Vol. 7, Pages 594: Serine Protease Autotransporters of the Enterobacteriaceae (SPATEs): Out and About and Chopping It UpMicroorganisms doi: 10.3390/microorganisms7120594Authors: Pokharel Habouria Bessaiah DozoisAutotransporters are secreted proteins with multiple functions produced by a variety of Gram-negative bacteria. In Enterobacteriaceae, a subgroup of these autotransporters are the SPATEs (serine protease autotransporters of Enterobacteriaceae). SPATEs play a crucial role in...
Thu Nov 21, 2019 02:00
Microorganisms, Vol. 7, Pages 593: MALDI-TOF Mass Spectrometry and Specific Biomarkers: Potential New Key for Swift Identification of Antimicrobial Resistance in Foodborne Pathogens.Microorganisms doi: 10.3390/microorganisms7120593Authors: Feucherolles Cauchie PennyMatrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) is today the reference method for direct identification of microorganisms in diagnostic laboratories, as it is notably time- and cost-efficient....
Thu Nov 21, 2019 02:00
Molbank, Vol. 2019, Article M1094: Paenidigyamycin G: 1-Acetyl-2,4-dimethyl-3-phenethyl-1H-imidazol-3-ium Molbank doi: 10.3390/M1094 Authors: Gilbert Mawuli Tetevi Samuel Kwain Thomas Mensah Anil Sazak Camas Mustafa Camas Aboagye Kwarteng Dofuor Faustus Akankperiwen Azerigyik Emmanuel Oluwabusola Hai Deng Marcel Jaspars Kwaku Kyeremeh The Ghanaian Paenibacillus sp. DE2SH (GenBank Accession Number: MH091697) is a prolific producer of potent antiparasitic...
Thu Nov 21, 2019 02:00
Molecules, Vol. 24, Pages 4251: Curdlan (Alcaligenes faecalis) (1→3)-β-d-Glucan Oligosaccharides Drive M1 Phenotype Polarization in Murine Bone Marrow-Derived Macrophages via Activation of MAPKs and NF-κB Pathways Molecules doi: 10.3390/molecules24234251 Authors: Jun Liu Jiqing Tang Xiuting Li Qiaojuan Yan Junwen Ma Zhengqiang Jiang Functional oligosaccharides, particularly curdlan (1→3)-β-d-glucan oligosaccharides (GOS), play important roles in modulating...
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Molecules, Vol. 24, Pages 4250: IR Studies of the Cu Ions in Cu-Faujasites Molecules doi: 10.3390/molecules24234250 Authors: Łukasz Kuterasiński Jerzy Podobiński Dorota Rutkowska-Zbik Jerzy Datka The properties of Cu ions in dealuminated faujasite-type zeolites (Si/Al = 31) containing 1, 2, and 5 wt.% of Cu were investigated by IR spectroscopy with CO and NO as probe molecules. Cu was introduced by impregnation into zeolites in both protonic (HFAU) and sodium (NaFAU) forms of...
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Molecules, Vol. 24, Pages 4252: Synthesis and Characterization of Unsymmetrical Double-Decker Siloxane (Basket Cage) Molecules doi: 10.3390/molecules24234252 Authors: Rungthip Kunthom Nobuhiro Takeda Masafumi Unno The one-pot synthesis of an unsymmetrical double-decker siloxane with a novel structure via the reaction of double-decker tetrasodiumsilanolate with 1 equiv. of dichlorotetraphenyldisiloxane in the presence of an acid is reported herein for the first time. The target...
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Molecules, Vol. 24, Pages 4249: Improving the Light-Induced Spin Transition Efficiency in Ni(II)-Based Macrocyclic-Ligand Complexes Molecules doi: 10.3390/molecules24234249 Authors: Alex-Adrian Farcaș Attila Bende The structural stability and photoabsorption properties of Ni(II)-based metal-organic complexes with octahedral coordination having different planar ligand ring structures were investigated employing density functional theory (DFT) and its time-dependent extension (TD-DFT)...
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Molecules, Vol. 24, Pages 4247: Graphene Oxide: A Smart (Starting) Material for Natural Methylxanthines Adsorption and Detection Molecules doi: 10.3390/molecules24234247 Authors: Rita Petrucci Isabella Chiarotto Leonardo Mattiello Daniele Passeri Marco Rossi Giuseppe Zollo and Marta Feroci Natural methylxanthines, caffeine, theophylline and theobromine, are widespread biologically active alkaloids in human nutrition, found mainly in beverages (coffee, tea, cocoa, energy...
Thu Nov 21, 2019 02:00
Molecules, Vol. 24, Pages 4246: Phytofabrication of Nanoparticles as Novel Drugs for Anticancer Applications Molecules doi: 10.3390/molecules24234246 Authors: Qi-Yao Wei Kai-Ming He Jin-Ling Chen Yan-Ming Xu Andy T. Y. Lau Cancer is one of the foremost causes of death globally and also the major stumbling block of increasing life expectancy. Although the primary treatment of surgical resection, chemotherapy, and radiotherapy have greatly reduced the mortality of cancer, the...
Thu Nov 21, 2019 02:00
Molecules, Vol. 24, Pages 4245: Formation of Prenylated Chalcone Xanthohumol Cocrystals: Single Crystal X-Ray Diffraction, Vibrational Spectroscopic Study Coupled with Multivariate Analysis Molecules doi: 10.3390/molecules24234245 Authors: Budziak Arczewska Kamiński Four novel xanthohumol (XN) cocrystals with pharmaceutically acceptable coformers, such as nicotinamide (NIC), glutarimide (GA), acetamide (AC), and caffeine (CF) in the 1:1 stoichiometry were obtained by the slow...
Thu Nov 21, 2019 02:00
Molecules, Vol. 24, Pages 4248: Mechanical Respond and Failure Mode of Large Size Honeycomb Sandwiched Composites under In-Plane Shear Load Molecules doi: 10.3390/molecules24234248 Authors: Wang Wang Liu Zhang Wan Zhang The present work focuses on the in-plane shear respond and failure mode of large size honeycomb sandwich composites which consist of plain weave carbon fabric laminate skins and aramid paper core. A special size specimen based on a typical element...
Thu Nov 21, 2019 02:00
Molecules, Vol. 24, Pages 4243: Nanostructured and Photochromic Material for Environmental Detection of Metal Ions Molecules doi: 10.3390/molecules24234243 Authors: Machado Alexis De Sousa Compared to conventional spectroscopy or chromatography analysis, chemical sensing based on colorimetric changes offers an alternative to monitor potential metal hazards in aqueous environment through rapid and low-cost colorimetric changes which can be easily interpreted. In this work poly(ethylene...
Thu Nov 21, 2019 02:00
Molecules, Vol. 24, Pages 4244: Volatiles of Black Pepper Fruits (Piper nigrum L.) Molecules doi: 10.3390/molecules24234244 Authors: Dosoky Satyal Barata da Silva Setzer Black pepper (Piper nigrum) is historically one of the most important spices and herbal medicines, and is now cultivated in tropical regions worldwide. The essential oil of black pepper fruits has shown a myriad of biological activities and is a commercially important commodity. In this work, five black...
Thu Nov 21, 2019 02:00
Molecules, Vol. 24, Pages 4241: UHPLC-ESI-MS/MS Quantitative Analyses of Multicomponent Hu Gan Tablets Molecules doi: 10.3390/molecules24234241 Authors: Jun Liang Xin-Dong Guo Fang Han Nowadays, the analysis of the multi-components in Chinese patent medicine prescriptions is being paid more attention. Therefore, in this study for the first time, a simple, rapid ultrahigh performance liquid chromatography–electrospray ionization tandem mass spectrometry (UHPLC-ESI-MS/MS)...
Thu Nov 21, 2019 02:00
Molecules, Vol. 24, Pages 4240: Changes in Arsenic and Copper Bioavailability and Oxytetracycline Degradation during the Composting Process Molecules doi: 10.3390/molecules24234240 Authors: Ebrahim Shehata Yuanwang Liu Yao Feng Dengmiao Cheng Zhaojun Li This research focuses on the effects of the composting process on oxytetracycline antibiotic degradation and the bioavailability of arsenic and copper. A compost experiment was conducted using cow and pig manure contaminated...
Thu Nov 21, 2019 02:00
Molecules, Vol. 24, Pages 4242: Food-Grade Nanoemulsions: Preparation, Stability and Application in Encapsulation of Bioactive Compounds Molecules doi: 10.3390/molecules24234242 Authors: Liu Huang Chen Lin Wang Nanoemulsions have attracted significant attention in food fields and can increase the functionality of the bioactive compounds contained within them. In this paper, the preparation methods, including low-energy and high-energy methods, were first reviewed. Second,...
Thu Nov 21, 2019 02:00
Molecules, Vol. 24, Pages 4239: Experimental Cannabinoid 2 Receptor Activation by Phyto-Derived and Synthetic Cannabinoid Ligands in LPS-Induced Interstitial Cystitis in Mice Molecules doi: 10.3390/molecules24234239 Authors: Geraint Berger Nipun Arora Ian Burkovskiy Yanfang Xia Anu Chinnadurai Robert Westhofen Georg Hagn Ashley Cox Melanie Kelly Juan Zhou Christian Lehmann Interstitial cystitis (IC) is a chronic bladder disorder with unclear etiology. The...
Thu Nov 21, 2019 02:00
Molecules, Vol. 24, Pages 4238: The Genus Nerine Herb. (Amaryllidaceae): Ethnobotany, Phytochemistry, and Biological Activity Molecules doi: 10.3390/molecules24234238 Authors: Cahlíková Vaněčková Šafratová Breiterová Blunden Hulcová Opletal Nerine Herbert, family Amaryllidaceae, is a genus of about 30 species that are native to South Africa, Botswana, Lesotho, Namibia, and Swatini (formerly known as Swaziland). Species of Nerine are autumn-flowering, perennial,...
Thu Nov 21, 2019 02:00
Molecules, Vol. 24, Pages 4237: Impact of Citral and Phloretin, Alone and in Combination, on Major Virulence Traits of Streptococcus pyogenes Molecules doi: 10.3390/molecules24234237 Authors: Mohd Adil Mohd Hassan Baig H.P. Vasantha Rupasinghe Streptococcus pyogenes is well documented as a multi-virulent and exclusively human pathogen. The LuxS-based signaling in these bacteria has a crucial role in causing several infections through pathways that are pathogenic. This study evaluated...
Thu Nov 21, 2019 02:00
Molecules, Vol. 24, Pages 4236: Design and Synthesis of New 6-Nitro and 6-Amino-3,3a,4,5-Tetrahydro-2H-Benzo[g]indazole Derivatives: Antiproliferative and Antibacterial Activity Molecules doi: 10.3390/molecules24234236 Authors: Cuartas Crespo Priego Persoons Daelemans Camarasa Insuasty Pérez-Pérez New substituted benzo[g]indazoles functionalized with a 6-nitro and 6-amino groups have been synthesized by the reaction of benzylidene tetralones with hydrazine...
Thu Nov 21, 2019 02:00
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