Abstract Background Familial adenomatous polyposis (FAP) is an Autosomal dominant inherited disorder and a rare form of colorectal cancer (CRC) that is characterized by the development of hundreds to thousands of adenomas in the rectum and colon. Mostly, cancers develop after the advent of the polyps. It appears in both sexes evenly, and the occurrence of the disease is in the second decade of life. Mitochondrial genome mutations have...
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Abstract Evidence-based treatment for youth with problematic sexual behavior (PSB) has the potential for a broad range of costs and benefits, raising the importance of querying its public health impact. This qualitative study examined the impact of treatment for youth with PSB through content analysis of interviews (N = 57) with service agency administrators, treatment providers, and professional stakeholders in communities where recent implementation of interventions for youth...
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Abstract The purpose of this paper is to describe how Chinese national adolescent mental health policy is translated into local plans and practice by means of the theoretical perspective of the policy triangle. Document analysis of national, provincial and local policy documents and semi-structured interviews with local policy actors were performed. National policies were implemented by a top-down process. The ministries were strong policy-makers on the national level, while the...
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Abstract Background The number of long-term survivors after allogeneic hematopoietic stem cell transplantation (HSCT) has increased recently. Esophageal squamous cell carcinoma occurs at a particularly high incidence as a secondary cancer after HSCT. However, standard treatment for these patients has not been established yet. The objectives of this study were to investigate outcomes of esophagectomy for esophageal carcinoma developed in...
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Microorganisms, Vol. 7, Pages 383: Food Preservatives Induce Proteobacteria Dysbiosis in Human-Microbiota Associated Nod2-Deficient Mice Microorganisms doi: 10.3390/microorganisms7100383 Authors: Hrncirova Machova Trckova Krejsek Hrncir : The worldwide incidence of many immune-mediated and metabolic diseases, initially affecting only the wealthy Western countries, is increasing rapidly. Many of these diseases are associated with the compositional and functional alterations...
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Microorganisms, Vol. 7, Pages 382: Metagenomic Insights and Genomic Analysis of Phosphogypsum and Its Associated Plant Endophytic Microbiomes Reveals Valuable Actors for Waste Bioremediation Microorganisms doi: 10.3390/microorganisms7100382 Authors: Ben Mefteh Bouket Daoud Luptakova Alenezi Gharsallah Belbahri The phosphogypsum (PG) endogenous bacterial community and endophytic bacterial communities of four plants growing in phosphogypsum-contaminated sites,...
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Microorganisms, Vol. 7, Pages 381: Microfluidic-Based Approaches for Foodborne Pathogen Detection Microorganisms doi: 10.3390/microorganisms7100381 Authors: Xihong Zhao Mei Li Yao Liu Food safety is of obvious importance, but there are frequent problems caused by foodborne pathogens that threaten the safety and health of human beings worldwide. Although the most classic method for detecting bacteria is the plate counting method, it takes almost three to seven days to get the bacterial...
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Microorganisms, Vol. 7, Pages 380: The Ecology of Subaerial Biofilms in Dry and Inhospitable Terrestrial Environments Microorganisms doi: 10.3390/microorganisms7100380 Authors: Federica Villa Francesca Cappitelli The ecological relationship between minerals and microorganisms arguably represents one of the most important associations in dry terrestrial environments, since it strongly influences major biochemical cycles and regulates the productivity and stability of the Earth’s...
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Biomolecules, Vol. 9, Pages 523: Combination of Transcriptomic, Proteomic, and Metabolomic Analysis Reveals the Ripening Mechanism of Banana Pulp Biomolecules doi: 10.3390/biom9100523 Authors: Li Yun Wu Qu Duan Jiang The banana is one of the most important fruits in the world. Bananas undergo a rapid ripening process after harvest, resulting in a short shelf. In this study, the mechanism underlying pulp ripening of harvested bananas was investigated using integrated...
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Biomolecules, Vol. 9, Pages 524: The Prevalence, Antibiotic Resistance and Biofilm Formation of Staphylococcus aureus in Bulk Ready-To-Eat Foods Biomolecules doi: 10.3390/biom9100524 Authors: Lin Sun Yao Cai Ren Chi The prevalence of Staphylococcus aureus in 2160 bulk ready-to-eat foods from the Sichuan province of China during 2013–2016 was investigated. The antibiotic resistance and the associated genes, as well as biofilm formation capacity of the S....
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Biomolecules, Vol. 9, Pages 522: New Insights into Structural and Functional Roles of Indole-3-acetic acid (IAA): Changes in DNA Topology and Gene Expression in Bacteria Biomolecules doi: 10.3390/biom9100522 Authors: Defez Valenti Andreozzi Romano Ciaramella Pesaresi Forlani Bianco : Indole-3-acetic acid (IAA) is a major plant hormone that affects many cellular processes in plants, bacteria, yeast, and human cells through still unknown mechanisms. In this...
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Biomolecules, Vol. 9, Pages 521: Antifungal Agents in Agriculture: Friends and Foes of Public Health
Biomolecules, Vol. 9, Pages 521: Antifungal Agents in Agriculture: Friends and Foes of Public Health Biomolecules doi: 10.3390/biom9100521 Authors: Veronica Soares Brauer Caroline Patini Rezende Andre Moreira Pessoni Renato Graciano De Paula Kanchugarakoppal S. Rangappa Siddaiah Chandra Nayaka Vijai Kumar Gupta Fausto Almeida Fungal diseases have been underestimated worldwide but constitute a substantial threat to several plant and animal species as well as to public...
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Nature Neuroscience, Published online: 23 September 2019; doi:10.1038/s41593-019-0496-ySun and Jin et al. report that a population of neurons in the subiculum form a pathway for visual information to reach the hippocampus and impact place-specific activity. Activation of these neurons promotes the formation of object-location memories.
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Nature Neuroscience, Published online: 23 September 2019; doi:10.1038/s41593-019-0487-zBy developing layer-specific functional MRI techniques for a high-order cognitive brain area, Finn et al. dissociate activity in superficial and deeper cortical layers during different periods of a working memory task in human dorsolateral prefrontal cortex.
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Nature Neuroscience, Published online: 23 September 2019; doi:10.1038/s41593-019-0486-0Microglia and astrocytes propagate neurodegeneration by releasing fragmented and dysfunctional mitochondria into the neuronal milieu. Inhibiting pathological fragmentation of glial mitochondria blunts neuroinflammation and increases neuroprotection.
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Nature Neuroscience, Published online: 23 September 2019; doi:10.1038/s41593-019-0489-xIn leukocyte transcriptomes from toddlers with ASD, Gazestani et al. find a perturbed gene network that is involved in fetal brain development and lies downstream of ASD risk genes, and whose dysregulation level correlates with ASD symptom severity.
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Abstract In the last years, there has been a significant increase in the number of cesarean deliveries and, with it, of the number of complications following the procedure. They can be divided into early and late ones. We will illustrate herein the most common complications following cesarean section to help radiologists to recognize them. To familiarize with these various pathologic conditions is crucial to alert referring clinicians for a prompt and appropriate maternal and...
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Abstract Objective To develop and assess the value and limitations of an image quality scoring criteria (IQSC) for pediatric CT exams. Methods IQSC was developed for subjective assessment of image quality using the scoring scale from 0 to 4, with 0 indicating desired anatomy or features not seen, 3 for adequate image quality, and 4 depicting...
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Abstract Background This study aimed to prospectively investigate patients’ satisfaction with briefings before computed tomography (CT) examinations, determine feasibility, and identify factors influencing patient satisfaction independent of patient and physician characteristics. Methods One hundred sixty patients received information by a radiologist...
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Abstract Background Diagnostic radiology residency programs pursuits as main objectives of the development of diagnostic capabilities and written communication skills to answer clinicians’ questions of referring clinicians. There has been also an increasing focus on competencies, rather than just education inputs. Then, to show ongoing professional development is necessary for a system to assess and document...
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Abstract The present survey describes the state-of-the-art techniques for dynamic cardiac magnetic resonance image reconstruction. Additionally, clinical relevance, main challenges, and future trends of this image modality are outlined. Thus, this paper aims to provide a general vision about cine MRI as the standard procedure in functional evaluation of the heart, focusing on technical methodologies.
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Abstract The presence of endoleaks remains one of the main drawbacks of endovascular repair of abdominal aortic aneurysms leading to the increase of the size of the aneurysmal sac and in most of the cases to repeated interventions. A variety of devices and percutaneous techniques have been developed so far to prevent and treat this phenomenon, including sealing of the aneurysmal sac, endovascular embolisation, and direct sac puncture. The aim of this review is to analyse the...
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Abstract Background Data used for training of deep learning networks usually needs large amounts of accurate labels. These labels are usually extracted from reports using natural language processing or by time-consuming manual review. The aim of this study was therefore to develop and evaluate a workflow for using data from structured reports as labels to be used in a deep learning application. ...
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Abstract Nowadays, hadrontherapy is increasingly used for the treatment of various tumors, in particular of those resistant to conventional radiotherapy. Proton and carbon ions are characterized by physical and biological features that allow a high radiation dose to tumors, minimizing irradiation to adjacent normal tissues. For this reason, radioresistant tumors and tumors located near highly radiosensitive critical organs, such as skull base tumors, represent the best target...
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Abstract Bibliometric analyses may indicate the most active journals, authors, countries, institutions and specialties by evaluating the most cited articles in a given research field. To the authors’ knowledge, there is no bibliometric analysis regarding neurocritical care research. Thus, the aim of this study is to analyze and to provide a scope of the current scientific production in this area. The 100 most cited articles in the neurocritical care research were retrieved from...
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Abstract Background/Objective Prognostication is a routine part of the delivery of neurocritical care for most patients with acute neurocritical illnesses. Numerous prognostic models exist for many different conditions. However, there are concerns about significant gaps in knowledge regarding optimal methods of prognostication. Methods As part...
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Abstract Background/Objective Children supported by extracorporeal membrane oxygenation (ECMO) are at risk of catastrophic neurologic injury and brain death. Timely determination of brain death is important for minimizing psychological distress for families, resource allocation, and organ donation. Reports of successful determination of brain death in pediatric patients supported by ECMO are limited. The determination of brain death...
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Abstract Introduction The primary goal of treatment in spinal metastasis is typically to extend patients’ lifespan as much as possible, and optimally to relieve the symptoms and so improve quality of life. It is crucial to avoid over- or under-treatment, according to each patient’s individual situation. Thus, this study aimed to identify significant prognostic factors for patients living with metastatic spine disease, and create a new...
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Abstract Background Radiation therapy (RT) remains a mainstay for the treatment of lower grade gliomas. Radiation neurotoxicity is a serious complication, carrying high morbidity in the absence of tumor progression. The incidence remains poorly categorized and known risk factors identified are related to the radiation modality. We hypothesized that patients with oligodendroglioma have a higher risk of radiation necrosis (RN) as compared...
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Zusammenfassung Die systematische mediastinale, hiläre und interlobäre Lymphknotendissektion (SLD) wird in der S3-Leitlinie zur Behandlung des operablen Lungenkarzinoms gefordert. Der Lymphknotenbefall gilt als einer der entscheidenden Prognosefaktoren. Die Art der Lymphknotenresektion ist immer wieder Gegenstand kontroverser Diskussionen. Sie ist für das Staging, die Prognose, das Überleben und die Rezidivrate wesentlich. Sie sollte standardisiert als Kompartimentdissektion, d. h....
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Abstract Background Telemedicine services are promoting more access to healthcare. Portugal was an early adopter of telemedicine to overcome both its geological barriers and the shortage of healthcare professionals. The Pediatric Cardiology Service (PCS) at Coimbra University Hospital Centre (CHUC) has been using telemedicine to increase access and coverage since 1998. Their Pediatric Telecardiology Service has been daily connecting...
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The original version of the article unfortunately contained a typo in the fourth author name. The author name was incorrectly listed as Rochelle Tixeria. The correct name should be Rochelle Tixeira. The original article has been corrected.
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